Amino acid dipepetide frequency for Agrobacterium vitis (strain S4 / ATCC BAA-846) (Rhizobium vitis (strain S4))

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	14.264AlaAla: 14.264 ± 0.116	1.03AlaCys: 1.03 ± 0.024	6.647AlaAsp: 6.647 ± 0.063	6.694AlaGlu: 6.694 ± 0.069	4.367AlaPhe: 4.367 ± 0.049	9.405AlaGly: 9.405 ± 0.082	2.114AlaHis: 2.114 ± 0.041	6.677AlaIle: 6.677 ± 0.072	4.554AlaLys: 4.554 ± 0.061	12.364AlaLeu: 12.364 ± 0.114	3.469AlaMet: 3.469 ± 0.044	3.167AlaAsn: 3.167 ± 0.047	4.536AlaPro: 4.536 ± 0.064	3.8AlaGln: 3.8 ± 0.051	7.207AlaArg: 7.207 ± 0.081	6.878AlaSer: 6.878 ± 0.077	5.7AlaThr: 5.7 ± 0.07	8.059AlaVal: 8.059 ± 0.073	1.266AlaTrp: 1.266 ± 0.027	2.571AlaTyr: 2.571 ± 0.042	0.0AlaXaa: 0.0 ± 0.0
Cys	0.883CysAla: 0.883 ± 0.023	0.115CysCys: 0.115 ± 0.008	0.515CysAsp: 0.515 ± 0.017	0.451CysGlu: 0.451 ± 0.014	0.328CysPhe: 0.328 ± 0.015	0.877CysGly: 0.877 ± 0.02	0.252CysHis: 0.252 ± 0.012	0.399CysIle: 0.399 ± 0.014	0.229CysLys: 0.229 ± 0.011	0.858CysLeu: 0.858 ± 0.023	0.168CysMet: 0.168 ± 0.01	0.223CysAsn: 0.223 ± 0.012	0.425CysPro: 0.425 ± 0.015	0.26CysGln: 0.26 ± 0.011	0.603CysArg: 0.603 ± 0.019	0.469CysSer: 0.469 ± 0.017	0.384CysThr: 0.384 ± 0.016	0.567CysVal: 0.567 ± 0.021	0.108CysTrp: 0.108 ± 0.008	0.211CysTyr: 0.211 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	6.377AspAla: 6.377 ± 0.069	0.503AspCys: 0.503 ± 0.018	3.081AspAsp: 3.081 ± 0.048	3.336AspGlu: 3.336 ± 0.05	2.365AspPhe: 2.365 ± 0.039	5.073AspGly: 5.073 ± 0.073	1.334AspHis: 1.334 ± 0.029	3.566AspIle: 3.566 ± 0.044	2.098AspLys: 2.098 ± 0.036	6.122AspLeu: 6.122 ± 0.063	1.515AspMet: 1.515 ± 0.028	1.602AspAsn: 1.602 ± 0.036	3.239AspPro: 3.239 ± 0.045	1.911AspGln: 1.911 ± 0.037	4.021AspArg: 4.021 ± 0.058	2.325AspSer: 2.325 ± 0.038	2.737AspThr: 2.737 ± 0.062	4.079AspVal: 4.079 ± 0.054	0.976AspTrp: 0.976 ± 0.026	1.647AspTyr: 1.647 ± 0.033	0.0AspXaa: 0.0 ± 0.0
Glu	6.844GluAla: 6.844 ± 0.072	0.344GluCys: 0.344 ± 0.015	2.938GluAsp: 2.938 ± 0.047	3.114GluGlu: 3.114 ± 0.054	1.823GluPhe: 1.823 ± 0.032	3.84GluGly: 3.84 ± 0.054	1.186GluHis: 1.186 ± 0.029	3.654GluIle: 3.654 ± 0.048	2.749GluLys: 2.749 ± 0.042	4.856GluLeu: 4.856 ± 0.059	1.478GluMet: 1.478 ± 0.028	1.803GluAsn: 1.803 ± 0.029	2.536GluPro: 2.536 ± 0.046	2.33GluGln: 2.33 ± 0.044	4.403GluArg: 4.403 ± 0.057	2.305GluSer: 2.305 ± 0.037	3.721GluThr: 3.721 ± 0.051	3.483GluVal: 3.483 ± 0.05	0.646GluTrp: 0.646 ± 0.017	0.955GluTyr: 0.955 ± 0.026	0.0GluXaa: 0.0 ± 0.0
Phe	4.355PheAla: 4.355 ± 0.051	0.439PheCys: 0.439 ± 0.017	2.754PheAsp: 2.754 ± 0.041	2.207PheGlu: 2.207 ± 0.034	1.533PhePhe: 1.533 ± 0.038	3.61PheGly: 3.61 ± 0.054	0.803PheHis: 0.803 ± 0.023	1.985PheIle: 1.985 ± 0.034	1.276PheLys: 1.276 ± 0.027	3.51PheLeu: 3.51 ± 0.049	0.865PheMet: 0.865 ± 0.023	1.254PheAsn: 1.254 ± 0.026	1.645PhePro: 1.645 ± 0.031	1.215PheGln: 1.215 ± 0.026	2.234PheArg: 2.234 ± 0.034	2.734PheSer: 2.734 ± 0.044	2.108PheThr: 2.108 ± 0.038	2.739PheVal: 2.739 ± 0.04	0.528PheTrp: 0.528 ± 0.019	0.961PheTyr: 0.961 ± 0.022	0.0PheXaa: 0.0 ± 0.0
Gly	7.961GlyAla: 7.961 ± 0.075	0.78GlyCys: 0.78 ± 0.022	4.304GlyAsp: 4.304 ± 0.064	4.589GlyGlu: 4.589 ± 0.052	3.733GlyPhe: 3.733 ± 0.049	6.601GlyGly: 6.601 ± 0.094	1.834GlyHis: 1.834 ± 0.033	4.762GlyIle: 4.762 ± 0.054	3.759GlyLys: 3.759 ± 0.048	8.836GlyLeu: 8.836 ± 0.084	2.345GlyMet: 2.345 ± 0.035	2.402GlyAsn: 2.402 ± 0.044	3.198GlyPro: 3.198 ± 0.044	2.992GlyGln: 2.992 ± 0.049	5.274GlyArg: 5.274 ± 0.071	4.933GlySer: 4.933 ± 0.073	4.427GlyThr: 4.427 ± 0.075	5.609GlyVal: 5.609 ± 0.065	1.192GlyTrp: 1.192 ± 0.03	2.334GlyTyr: 2.334 ± 0.038	0.0GlyXaa: 0.0 ± 0.0
His	2.164HisAla: 2.164 ± 0.037	0.219HisCys: 0.219 ± 0.011	1.299HisAsp: 1.299 ± 0.028	1.041HisGlu: 1.041 ± 0.025	0.92HisPhe: 0.92 ± 0.023	1.893HisGly: 1.893 ± 0.034	0.617HisHis: 0.617 ± 0.021	1.112HisIle: 1.112 ± 0.027	0.58HisLys: 0.58 ± 0.021	2.13HisLeu: 2.13 ± 0.037	0.529HisMet: 0.529 ± 0.018	0.523HisAsn: 0.523 ± 0.016	1.269HisPro: 1.269 ± 0.03	0.727HisGln: 0.727 ± 0.023	1.402HisArg: 1.402 ± 0.031	1.081HisSer: 1.081 ± 0.027	0.845HisThr: 0.845 ± 0.022	1.462HisVal: 1.462 ± 0.029	0.324HisTrp: 0.324 ± 0.014	0.597HisTyr: 0.597 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	7.667IleAla: 7.667 ± 0.065	0.58IleCys: 0.58 ± 0.019	3.908IleAsp: 3.908 ± 0.045	3.642IleGlu: 3.642 ± 0.05	2.017IlePhe: 2.017 ± 0.04	5.407IleGly: 5.407 ± 0.057	0.994IleHis: 0.994 ± 0.022	2.857IleIle: 2.857 ± 0.047	1.824IleLys: 1.824 ± 0.034	4.939IleLeu: 4.939 ± 0.066	1.104IleMet: 1.104 ± 0.029	1.794IleAsn: 1.794 ± 0.032	2.427IlePro: 2.427 ± 0.038	1.391IleGln: 1.391 ± 0.03	3.479IleArg: 3.479 ± 0.046	3.677IleSer: 3.677 ± 0.05	3.101IleThr: 3.101 ± 0.051	4.254IleVal: 4.254 ± 0.055	0.61IleTrp: 0.61 ± 0.019	1.244IleTyr: 1.244 ± 0.028	0.0IleXaa: 0.0 ± 0.0
Lys	5.013LysAla: 5.013 ± 0.072	0.176LysCys: 0.176 ± 0.01	2.107LysAsp: 2.107 ± 0.037	1.748LysGlu: 1.748 ± 0.032	1.061LysPhe: 1.061 ± 0.024	3.043LysGly: 3.043 ± 0.045	0.657LysHis: 0.657 ± 0.022	2.223LysIle: 2.223 ± 0.035	1.531LysLys: 1.531 ± 0.037	3.796LysLeu: 3.796 ± 0.046	0.932LysMet: 0.932 ± 0.022	1.094LysAsn: 1.094 ± 0.026	2.471LysPro: 2.471 ± 0.051	1.339LysGln: 1.339 ± 0.031	2.529LysArg: 2.529 ± 0.042	2.407LysSer: 2.407 ± 0.039	2.603LysThr: 2.603 ± 0.044	2.676LysVal: 2.676 ± 0.047	0.412LysTrp: 0.412 ± 0.016	0.695LysTyr: 0.695 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	12.43LeuAla: 12.43 ± 0.109	0.891LeuCys: 0.891 ± 0.023	6.015LeuAsp: 6.015 ± 0.062	5.24LeuGlu: 5.24 ± 0.059	3.694LeuPhe: 3.694 ± 0.061	7.83LeuGly: 7.83 ± 0.076	1.904LeuHis: 1.904 ± 0.036	5.346LeuIle: 5.346 ± 0.054	4.313LeuLys: 4.313 ± 0.052	9.49LeuLeu: 9.49 ± 0.11	2.474LeuMet: 2.474 ± 0.039	2.833LeuAsn: 2.833 ± 0.035	5.343LeuPro: 5.343 ± 0.068	3.064LeuGln: 3.064 ± 0.05	6.122LeuArg: 6.122 ± 0.063	7.417LeuSer: 7.417 ± 0.066	5.899LeuThr: 5.899 ± 0.061	7.165LeuVal: 7.165 ± 0.072	1.118LeuTrp: 1.118 ± 0.026	2.144LeuTyr: 2.144 ± 0.034	0.0LeuXaa: 0.0 ± 0.0
Met	3.203MetAla: 3.203 ± 0.043	0.144MetCys: 0.144 ± 0.009	1.266MetAsp: 1.266 ± 0.024	1.233MetGlu: 1.233 ± 0.028	0.711MetPhe: 0.711 ± 0.019	1.723MetGly: 1.723 ± 0.038	0.435MetHis: 0.435 ± 0.015	1.58MetIle: 1.58 ± 0.033	1.066MetLys: 1.066 ± 0.025	2.514MetLeu: 2.514 ± 0.039	0.77MetMet: 0.77 ± 0.022	0.853MetAsn: 0.853 ± 0.023	1.529MetPro: 1.529 ± 0.031	0.973MetGln: 0.973 ± 0.025	1.761MetArg: 1.761 ± 0.029	1.772MetSer: 1.772 ± 0.032	2.073MetThr: 2.073 ± 0.036	1.9MetVal: 1.9 ± 0.035	0.187MetTrp: 0.187 ± 0.012	0.305MetTyr: 0.305 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	3.333AsnAla: 3.333 ± 0.041	0.247AsnCys: 0.247 ± 0.012	1.667AsnAsp: 1.667 ± 0.037	1.336AsnGlu: 1.336 ± 0.03	1.167AsnPhe: 1.167 ± 0.025	2.746AsnGly: 2.746 ± 0.045	0.636AsnHis: 0.636 ± 0.02	1.631AsnIle: 1.631 ± 0.032	0.884AsnLys: 0.884 ± 0.024	2.837AsnLeu: 2.837 ± 0.047	0.695AsnMet: 0.695 ± 0.023	0.846AsnAsn: 0.846 ± 0.025	1.943AsnPro: 1.943 ± 0.037	0.948AsnGln: 0.948 ± 0.026	2.017AsnArg: 2.017 ± 0.035	1.653AsnSer: 1.653 ± 0.038	1.451AsnThr: 1.451 ± 0.035	2.032AsnVal: 2.032 ± 0.039	0.484AsnTrp: 0.484 ± 0.018	0.74AsnTyr: 0.74 ± 0.024	0.0AsnXaa: 0.0 ± 0.0
Pro	5.308ProAla: 5.308 ± 0.068	0.315ProCys: 0.315 ± 0.013	3.506ProAsp: 3.506 ± 0.052	3.231ProGlu: 3.231 ± 0.048	2.02ProPhe: 2.02 ± 0.034	4.119ProGly: 4.119 ± 0.058	1.076ProHis: 1.076 ± 0.027	2.366ProIle: 2.366 ± 0.039	1.909ProLys: 1.909 ± 0.033	4.69ProLeu: 4.69 ± 0.055	1.196ProMet: 1.196 ± 0.025	1.321ProAsn: 1.321 ± 0.028	2.225ProPro: 2.225 ± 0.055	1.874ProGln: 1.874 ± 0.038	2.418ProArg: 2.418 ± 0.042	2.938ProSer: 2.938 ± 0.047	2.369ProThr: 2.369 ± 0.039	4.197ProVal: 4.197 ± 0.051	0.603ProTrp: 0.603 ± 0.018	1.232ProTyr: 1.232 ± 0.03	0.0ProXaa: 0.0 ± 0.0
Gln	4.349GlnAla: 4.349 ± 0.058	0.213GlnCys: 0.213 ± 0.01	1.663GlnAsp: 1.663 ± 0.027	1.65GlnGlu: 1.65 ± 0.033	1.187GlnPhe: 1.187 ± 0.027	2.489GlnGly: 2.489 ± 0.043	0.705GlnHis: 0.705 ± 0.022	2.141GlnIle: 2.141 ± 0.036	1.397GlnLys: 1.397 ± 0.028	3.118GlnLeu: 3.118 ± 0.043	1.017GlnMet: 1.017 ± 0.028	1.044GlnAsn: 1.044 ± 0.027	1.902GlnPro: 1.902 ± 0.038	1.557GlnGln: 1.557 ± 0.038	2.365GlnArg: 2.365 ± 0.042	2.253GlnSer: 2.253 ± 0.037	2.078GlnThr: 2.078 ± 0.035	2.31GlnVal: 2.31 ± 0.041	0.443GlnTrp: 0.443 ± 0.018	0.667GlnTyr: 0.667 ± 0.019	0.0GlnXaa: 0.0 ± 0.0
Arg	6.366ArgAla: 6.366 ± 0.073	0.458ArgCys: 0.458 ± 0.018	3.819ArgAsp: 3.819 ± 0.054	3.588ArgGlu: 3.588 ± 0.051	2.879ArgPhe: 2.879 ± 0.043	4.109ArgGly: 4.109 ± 0.056	1.728ArgHis: 1.728 ± 0.029	3.888ArgIle: 3.888 ± 0.044	2.47ArgLys: 2.47 ± 0.04	7.314ArgLeu: 7.314 ± 0.074	1.81ArgMet: 1.81 ± 0.031	1.944ArgAsn: 1.944 ± 0.032	3.085ArgPro: 3.085 ± 0.045	2.914ArgGln: 2.914 ± 0.045	4.761ArgArg: 4.761 ± 0.066	3.739ArgSer: 3.739 ± 0.051	3.022ArgThr: 3.022 ± 0.047	4.049ArgVal: 4.049 ± 0.05	0.856ArgTrp: 0.856 ± 0.025	1.668ArgTyr: 1.668 ± 0.031	0.0ArgXaa: 0.0 ± 0.0
Ser	6.424SerAla: 6.424 ± 0.072	0.465SerCys: 0.465 ± 0.017	3.384SerAsp: 3.384 ± 0.054	3.018SerGlu: 3.018 ± 0.038	2.594SerPhe: 2.594 ± 0.043	5.982SerGly: 5.982 ± 0.068	1.294SerHis: 1.294 ± 0.027	3.383SerIle: 3.383 ± 0.047	2.071SerLys: 2.071 ± 0.038	6.221SerLeu: 6.221 ± 0.071	1.529SerMet: 1.529 ± 0.028	1.78SerAsn: 1.78 ± 0.036	2.9SerPro: 2.9 ± 0.036	2.056SerGln: 2.056 ± 0.037	3.81SerArg: 3.81 ± 0.05	3.868SerSer: 3.868 ± 0.063	3.201SerThr: 3.201 ± 0.052	4.376SerVal: 4.376 ± 0.057	0.808SerTrp: 0.808 ± 0.02	1.534SerTyr: 1.534 ± 0.032	0.0SerXaa: 0.0 ± 0.0
Thr	6.117ThrAla: 6.117 ± 0.074	0.423ThrCys: 0.423 ± 0.015	2.953ThrAsp: 2.953 ± 0.041	2.737ThrGlu: 2.737 ± 0.042	2.07ThrPhe: 2.07 ± 0.037	5.052ThrGly: 5.052 ± 0.068	1.066ThrHis: 1.066 ± 0.023	3.354ThrIle: 3.354 ± 0.052	1.789ThrLys: 1.789 ± 0.034	6.012ThrLeu: 6.012 ± 0.06	1.329ThrMet: 1.329 ± 0.031	1.478ThrAsn: 1.478 ± 0.034	3.081ThrPro: 3.081 ± 0.043	1.615ThrGln: 1.615 ± 0.031	3.077ThrArg: 3.077 ± 0.04	3.334ThrSer: 3.334 ± 0.049	2.98ThrThr: 2.98 ± 0.058	4.753ThrVal: 4.753 ± 0.068	0.66ThrTrp: 0.66 ± 0.02	1.288ThrTyr: 1.288 ± 0.029	0.0ThrXaa: 0.0 ± 0.0
Val	8.144ValAla: 8.144 ± 0.068	0.607ValCys: 0.607 ± 0.018	3.998ValAsp: 3.998 ± 0.051	4.378ValGlu: 4.378 ± 0.05	2.775ValPhe: 2.775 ± 0.043	5.099ValGly: 5.099 ± 0.059	1.3ValHis: 1.3 ± 0.027	4.265ValIle: 4.265 ± 0.056	2.76ValLys: 2.76 ± 0.045	7.213ValLeu: 7.213 ± 0.066	1.916ValMet: 1.916 ± 0.032	2.151ValAsn: 2.151 ± 0.037	3.382ValPro: 3.382 ± 0.049	2.095ValGln: 2.095 ± 0.032	4.264ValArg: 4.264 ± 0.045	4.762ValSer: 4.762 ± 0.053	4.589ValThr: 4.589 ± 0.07	5.482ValVal: 5.482 ± 0.067	0.853ValTrp: 0.853 ± 0.023	1.477ValTyr: 1.477 ± 0.031	0.0ValXaa: 0.0 ± 0.0
Trp	1.13TrpAla: 1.13 ± 0.028	0.126TrpCys: 0.126 ± 0.008	0.586TrpAsp: 0.586 ± 0.019	0.541TrpGlu: 0.541 ± 0.015	0.542TrpPhe: 0.542 ± 0.018	0.805TrpGly: 0.805 ± 0.025	0.292TrpHis: 0.292 ± 0.013	0.647TrpIle: 0.647 ± 0.019	0.522TrpLys: 0.522 ± 0.016	1.533TrpLeu: 1.533 ± 0.035	0.362TrpMet: 0.362 ± 0.012	0.487TrpAsn: 0.487 ± 0.016	0.64TrpPro: 0.64 ± 0.021	0.642TrpGln: 0.642 ± 0.017	1.0TrpArg: 1.0 ± 0.022	0.813TrpSer: 0.813 ± 0.025	0.721TrpThr: 0.721 ± 0.022	0.718TrpVal: 0.718 ± 0.021	0.187TrpTrp: 0.187 ± 0.011	0.328TrpTyr: 0.328 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.435TyrAla: 2.435 ± 0.041	0.25TyrCys: 0.25 ± 0.011	1.497TyrAsp: 1.497 ± 0.03	1.231TyrGlu: 1.231 ± 0.026	0.969TyrPhe: 0.969 ± 0.026	2.163TyrGly: 2.163 ± 0.035	0.51TyrHis: 0.51 ± 0.019	1.077TyrIle: 1.077 ± 0.023	0.731TyrLys: 0.731 ± 0.021	2.379TyrLeu: 2.379 ± 0.039	0.494TyrMet: 0.494 ± 0.016	0.697TyrAsn: 0.697 ± 0.02	1.137TyrPro: 1.137 ± 0.028	0.846TyrGln: 0.846 ± 0.017	1.72TyrArg: 1.72 ± 0.031	1.34TyrSer: 1.34 ± 0.032	1.157TyrThr: 1.157 ± 0.03	1.6TyrVal: 1.6 ± 0.032	0.365TyrTrp: 0.365 ± 0.016	0.652TyrTyr: 0.652 ± 0.021	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5353 proteins (1783039 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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