Amino acid dipepetide frequency for Moumouvirus australiensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.218AlaAla: 1.218 ± 0.085
0.957AlaCys: 0.957 ± 0.074
1.956AlaAsp: 1.956 ± 0.125
1.39AlaGlu: 1.39 ± 0.082
1.348AlaPhe: 1.348 ± 0.084
1.546AlaGly: 1.546 ± 0.105
0.534AlaHis: 0.534 ± 0.04
2.779AlaIle: 2.779 ± 0.124
2.248AlaLys: 2.248 ± 0.103
2.566AlaLeu: 2.566 ± 0.122
0.531AlaMet: 0.531 ± 0.043
2.493AlaAsn: 2.493 ± 0.117
0.875AlaPro: 0.875 ± 0.082
1.046AlaGln: 1.046 ± 0.079
1.021AlaArg: 1.021 ± 0.071
2.589AlaSer: 2.589 ± 0.184
1.456AlaThr: 1.456 ± 0.093
1.717AlaVal: 1.717 ± 0.112
0.172AlaTrp: 0.172 ± 0.026
1.272AlaTyr: 1.272 ± 0.069
0.0AlaXaa: 0.0 ± 0.0
Cys
0.658CysAla: 0.658 ± 0.062
0.413CysCys: 0.413 ± 0.049
1.243CysAsp: 1.243 ± 0.07
1.059CysGlu: 1.059 ± 0.071
0.776CysPhe: 0.776 ± 0.056
1.212CysGly: 1.212 ± 0.096
0.487CysHis: 0.487 ± 0.039
2.423CysIle: 2.423 ± 0.215
1.38CysLys: 1.38 ± 0.075
1.507CysLeu: 1.507 ± 0.083
0.347CysMet: 0.347 ± 0.038
1.126CysAsn: 1.126 ± 0.066
0.671CysPro: 0.671 ± 0.062
0.547CysGln: 0.547 ± 0.048
0.633CysArg: 0.633 ± 0.047
0.967CysSer: 0.967 ± 0.077
0.703CysThr: 0.703 ± 0.048
0.938CysVal: 0.938 ± 0.061
0.149CysTrp: 0.149 ± 0.022
0.811CysTyr: 0.811 ± 0.062
0.0CysXaa: 0.0 ± 0.0
Asp
1.542AspAla: 1.542 ± 0.082
0.89AspCys: 0.89 ± 0.07
4.01AspAsp: 4.01 ± 0.137
3.794AspGlu: 3.794 ± 0.132
3.52AspPhe: 3.52 ± 0.1
2.105AspGly: 2.105 ± 0.101
1.1AspHis: 1.1 ± 0.066
7.658AspIle: 7.658 ± 0.19
8.112AspLys: 8.112 ± 0.931
6.036AspLeu: 6.036 ± 0.278
1.208AspMet: 1.208 ± 0.06
5.502AspAsn: 5.502 ± 0.148
2.15AspPro: 2.15 ± 0.1
1.644AspGln: 1.644 ± 0.068
1.456AspArg: 1.456 ± 0.074
3.902AspSer: 3.902 ± 0.121
2.493AspThr: 2.493 ± 0.084
3.107AspVal: 3.107 ± 0.115
0.591AspTrp: 0.591 ± 0.052
3.803AspTyr: 3.803 ± 0.146
0.0AspXaa: 0.0 ± 0.0
Glu
1.549GluAla: 1.549 ± 0.082
1.008GluCys: 1.008 ± 0.063
2.992GluAsp: 2.992 ± 0.118
3.485GluGlu: 3.485 ± 0.166
3.11GluPhe: 3.11 ± 0.114
1.972GluGly: 1.972 ± 0.113
0.875GluHis: 0.875 ± 0.053
6.23GluIle: 6.23 ± 0.184
5.75GluLys: 5.75 ± 0.181
4.897GluLeu: 4.897 ± 0.162
1.123GluMet: 1.123 ± 0.057
6.297GluAsn: 6.297 ± 0.205
1.485GluPro: 1.485 ± 0.159
1.666GluGln: 1.666 ± 0.122
1.584GluArg: 1.584 ± 0.083
3.94GluSer: 3.94 ± 0.133
2.779GluThr: 2.779 ± 0.103
2.21GluVal: 2.21 ± 0.126
0.404GluTrp: 0.404 ± 0.037
3.473GluTyr: 3.473 ± 0.117
0.0GluXaa: 0.0 ± 0.0
Phe
1.262PheAla: 1.262 ± 0.08
0.894PheCys: 0.894 ± 0.056
3.648PheAsp: 3.648 ± 0.113
2.808PheGlu: 2.808 ± 0.105
2.038PhePhe: 2.038 ± 0.093
3.717PheGly: 3.717 ± 0.247
0.766PheHis: 0.766 ± 0.05
4.382PheIle: 4.382 ± 0.143
3.883PheLys: 3.883 ± 0.147
3.698PheLeu: 3.698 ± 0.115
1.005PheMet: 1.005 ± 0.056
5.724PheAsn: 5.724 ± 0.292
1.259PhePro: 1.259 ± 0.065
1.313PheGln: 1.313 ± 0.069
1.402PheArg: 1.402 ± 0.073
3.05PheSer: 3.05 ± 0.101
2.347PheThr: 2.347 ± 0.094
2.204PheVal: 2.204 ± 0.087
0.343PheTrp: 0.343 ± 0.034
2.665PheTyr: 2.665 ± 0.101
0.0PheXaa: 0.0 ± 0.0
Gly
2.496GlyAla: 2.496 ± 0.189
1.803GlyCys: 1.803 ± 0.209
6.322GlyAsp: 6.322 ± 1.368
2.445GlyGlu: 2.445 ± 0.168
2.21GlyPhe: 2.21 ± 0.101
2.767GlyGly: 2.767 ± 0.262
1.418GlyHis: 1.418 ± 0.126
3.886GlyIle: 3.886 ± 0.142
3.549GlyLys: 3.549 ± 0.123
3.393GlyLeu: 3.393 ± 0.125
0.747GlyMet: 0.747 ± 0.11
4.045GlyAsn: 4.045 ± 0.304
1.272GlyPro: 1.272 ± 0.123
1.332GlyGln: 1.332 ± 0.094
1.402GlyArg: 1.402 ± 0.079
3.473GlySer: 3.473 ± 0.288
2.458GlyThr: 2.458 ± 0.149
2.182GlyVal: 2.182 ± 0.095
0.646GlyTrp: 0.646 ± 0.065
2.776GlyTyr: 2.776 ± 0.135
0.0GlyXaa: 0.0 ± 0.0
His
0.623HisAla: 0.623 ± 0.045
0.375HisCys: 0.375 ± 0.036
1.11HisAsp: 1.11 ± 0.065
0.932HisGlu: 0.932 ± 0.054
0.938HisPhe: 0.938 ± 0.053
0.852HisGly: 0.852 ± 0.054
0.528HisHis: 0.528 ± 0.082
1.844HisIle: 1.844 ± 0.092
1.72HisLys: 1.72 ± 0.079
3.415HisLeu: 3.415 ± 0.275
0.337HisMet: 0.337 ± 0.033
1.546HisAsn: 1.546 ± 0.068
0.677HisPro: 0.677 ± 0.044
0.531HisGln: 0.531 ± 0.045
0.623HisArg: 0.623 ± 0.043
0.935HisSer: 0.935 ± 0.055
0.817HisThr: 0.817 ± 0.05
0.817HisVal: 0.817 ± 0.056
0.149HisTrp: 0.149 ± 0.023
0.964HisTyr: 0.964 ± 0.061
0.0HisXaa: 0.0 ± 0.0
Ile
2.541IleAla: 2.541 ± 0.108
1.784IleCys: 1.784 ± 0.085
6.395IleAsp: 6.395 ± 0.175
5.918IleGlu: 5.918 ± 0.172
4.834IlePhe: 4.834 ± 0.143
3.972IleGly: 3.972 ± 0.213
1.975IleHis: 1.975 ± 0.097
10.882IleIle: 10.882 ± 0.264
10.981IleLys: 10.981 ± 0.258
8.287IleLeu: 8.287 ± 0.195
1.816IleMet: 1.816 ± 0.075
10.272IleAsn: 10.272 ± 0.306
5.034IlePro: 5.034 ± 0.304
2.589IleGln: 2.589 ± 0.126
3.056IleArg: 3.056 ± 0.112
6.662IleSer: 6.662 ± 0.17
4.824IleThr: 4.824 ± 0.145
4.481IleVal: 4.481 ± 0.148
0.728IleTrp: 0.728 ± 0.051
5.435IleTyr: 5.435 ± 0.143
0.0IleXaa: 0.0 ± 0.0
Lys
1.698LysAla: 1.698 ± 0.091
1.511LysCys: 1.511 ± 0.091
3.746LysAsp: 3.746 ± 0.122
4.392LysGlu: 4.392 ± 0.158
4.732LysPhe: 4.732 ± 0.164
6.65LysGly: 6.65 ± 1.3
1.555LysHis: 1.555 ± 0.075
10.717LysIle: 10.717 ± 0.276
9.333LysLys: 9.333 ± 0.321
7.661LysLeu: 7.661 ± 0.209
1.8LysMet: 1.8 ± 0.08
10.192LysAsn: 10.192 ± 0.261
2.29LysPro: 2.29 ± 0.12
2.43LysGln: 2.43 ± 0.1
2.258LysArg: 2.258 ± 0.11
5.734LysSer: 5.734 ± 0.186
4.29LysThr: 4.29 ± 0.146
2.709LysVal: 2.709 ± 0.112
0.817LysTrp: 0.817 ± 0.06
8.386LysTyr: 8.386 ± 0.229
0.0LysXaa: 0.0 ± 0.0
Leu
2.814LeuAla: 2.814 ± 0.105
1.158LeuCys: 1.158 ± 0.07
5.75LeuAsp: 5.75 ± 0.153
5.87LeuGlu: 5.87 ± 0.195
3.622LeuPhe: 3.622 ± 0.122
4.029LeuGly: 4.029 ± 0.305
1.444LeuHis: 1.444 ± 0.077
7.54LeuIle: 7.54 ± 0.212
7.581LeuLys: 7.581 ± 0.185
7.413LeuLeu: 7.413 ± 0.24
1.701LeuMet: 1.701 ± 0.099
6.843LeuAsn: 6.843 ± 0.198
2.846LeuPro: 2.846 ± 0.105
2.706LeuGln: 2.706 ± 0.112
2.7LeuArg: 2.7 ± 0.11
6.262LeuSer: 6.262 ± 0.149
4.627LeuThr: 4.627 ± 0.197
4.35LeuVal: 4.35 ± 0.154
0.499LeuTrp: 0.499 ± 0.045
3.746LeuTyr: 3.746 ± 0.118
0.0LeuXaa: 0.0 ± 0.0
Met
0.738MetAla: 0.738 ± 0.051
0.366MetCys: 0.366 ± 0.036
1.307MetAsp: 1.307 ± 0.061
1.18MetGlu: 1.18 ± 0.059
0.805MetPhe: 0.805 ± 0.049
1.059MetGly: 1.059 ± 0.117
0.302MetHis: 0.302 ± 0.03
1.733MetIle: 1.733 ± 0.08
1.415MetLys: 1.415 ± 0.077
1.307MetLeu: 1.307 ± 0.065
0.366MetMet: 0.366 ± 0.036
1.736MetAsn: 1.736 ± 0.123
0.515MetPro: 0.515 ± 0.042
0.499MetGln: 0.499 ± 0.045
0.604MetArg: 0.604 ± 0.048
1.72MetSer: 1.72 ± 0.073
1.056MetThr: 1.056 ± 0.068
0.811MetVal: 0.811 ± 0.054
0.146MetTrp: 0.146 ± 0.022
0.983MetTyr: 0.983 ± 0.06
0.0MetXaa: 0.0 ± 0.0
Asn
2.124AsnAla: 2.124 ± 0.094
1.275AsnCys: 1.275 ± 0.08
5.32AsnAsp: 5.32 ± 0.164
4.713AsnGlu: 4.713 ± 0.202
4.519AsnPhe: 4.519 ± 0.143
4.56AsnGly: 4.56 ± 0.189
1.787AsnHis: 1.787 ± 0.08
12.126AsnIle: 12.126 ± 0.272
8.971AsnLys: 8.971 ± 0.228
7.543AsnLeu: 7.543 ± 0.157
2.137AsnMet: 2.137 ± 0.118
11.311AsnAsn: 11.311 ± 0.365
3.05AsnPro: 3.05 ± 0.131
3.765AsnGln: 3.765 ± 0.26
2.401AsnArg: 2.401 ± 0.104
5.991AsnSer: 5.991 ± 0.196
4.582AsnThr: 4.582 ± 0.152
3.95AsnVal: 3.95 ± 0.134
0.766AsnTrp: 0.766 ± 0.074
5.346AsnTyr: 5.346 ± 0.167
0.0AsnXaa: 0.0 ± 0.0
Pro
0.909ProAla: 0.909 ± 0.081
0.601ProCys: 0.601 ± 0.127
2.379ProAsp: 2.379 ± 0.094
2.226ProGlu: 2.226 ± 0.093
1.402ProPhe: 1.402 ± 0.072
1.536ProGly: 1.536 ± 0.093
0.572ProHis: 0.572 ± 0.041
3.994ProIle: 3.994 ± 0.206
2.887ProLys: 2.887 ± 0.101
2.251ProLeu: 2.251 ± 0.107
0.48ProMet: 0.48 ± 0.048
3.711ProAsn: 3.711 ± 0.218
1.014ProPro: 1.014 ± 0.106
0.951ProGln: 0.951 ± 0.074
0.795ProArg: 0.795 ± 0.066
1.829ProSer: 1.829 ± 0.105
1.768ProThr: 1.768 ± 0.1
1.991ProVal: 1.991 ± 0.167
0.204ProTrp: 0.204 ± 0.029
1.466ProTyr: 1.466 ± 0.088
0.0ProXaa: 0.0 ± 0.0
Gln
0.986GlnAla: 0.986 ± 0.067
0.442GlnCys: 0.442 ± 0.043
1.666GlnAsp: 1.666 ± 0.096
1.644GlnGlu: 1.644 ± 0.079
1.361GlnPhe: 1.361 ± 0.068
0.976GlnGly: 0.976 ± 0.071
0.471GlnHis: 0.471 ± 0.04
3.062GlnIle: 3.062 ± 0.118
2.519GlnLys: 2.519 ± 0.104
2.382GlnLeu: 2.382 ± 0.084
0.646GlnMet: 0.646 ± 0.055
3.132GlnAsn: 3.132 ± 0.122
1.701GlnPro: 1.701 ± 0.196
1.253GlnGln: 1.253 ± 0.158
0.903GlnArg: 0.903 ± 0.07
2.013GlnSer: 2.013 ± 0.101
1.491GlnThr: 1.491 ± 0.081
1.482GlnVal: 1.482 ± 0.094
0.286GlnTrp: 0.286 ± 0.031
1.822GlnTyr: 1.822 ± 0.093
0.0GlnXaa: 0.0 ± 0.0
Arg
1.116ArgAla: 1.116 ± 0.08
0.611ArgCys: 0.611 ± 0.04
1.949ArgAsp: 1.949 ± 0.095
1.816ArgGlu: 1.816 ± 0.099
1.52ArgPhe: 1.52 ± 0.075
1.46ArgGly: 1.46 ± 0.083
0.534ArgHis: 0.534 ± 0.042
2.598ArgIle: 2.598 ± 0.086
2.503ArgLys: 2.503 ± 0.103
2.369ArgLeu: 2.369 ± 0.101
0.557ArgMet: 0.557 ± 0.043
2.62ArgAsn: 2.62 ± 0.119
0.906ArgPro: 0.906 ± 0.069
1.116ArgGln: 1.116 ± 0.075
1.199ArgArg: 1.199 ± 0.078
2.01ArgSer: 2.01 ± 0.167
1.282ArgThr: 1.282 ± 0.074
1.358ArgVal: 1.358 ± 0.072
0.337ArgTrp: 0.337 ± 0.04
1.644ArgTyr: 1.644 ± 0.082
0.0ArgXaa: 0.0 ± 0.0
Ser
2.013SerAla: 2.013 ± 0.134
1.202SerCys: 1.202 ± 0.076
4.713SerAsp: 4.713 ± 0.157
4.395SerGlu: 4.395 ± 0.162
2.709SerPhe: 2.709 ± 0.103
4.334SerGly: 4.334 ± 0.261
1.129SerHis: 1.129 ± 0.054
5.934SerIle: 5.934 ± 0.157
6.392SerLys: 6.392 ± 0.176
4.792SerLeu: 4.792 ± 0.141
1.278SerMet: 1.278 ± 0.082
5.721SerAsn: 5.721 ± 0.158
1.787SerPro: 1.787 ± 0.095
2.264SerGln: 2.264 ± 0.092
2.436SerArg: 2.436 ± 0.177
4.961SerSer: 4.961 ± 0.21
3.31SerThr: 3.31 ± 0.149
3.819SerVal: 3.819 ± 0.206
0.502SerTrp: 0.502 ± 0.035
2.818SerTyr: 2.818 ± 0.093
0.0SerXaa: 0.0 ± 0.0
Thr
1.565ThrAla: 1.565 ± 0.1
0.852ThrCys: 0.852 ± 0.052
2.751ThrAsp: 2.751 ± 0.101
2.63ThrGlu: 2.63 ± 0.094
2.827ThrPhe: 2.827 ± 0.172
2.846ThrGly: 2.846 ± 0.169
2.124ThrHis: 2.124 ± 0.232
4.684ThrIle: 4.684 ± 0.144
4.004ThrLys: 4.004 ± 0.147
3.597ThrLeu: 3.597 ± 0.105
0.722ThrMet: 0.722 ± 0.05
4.382ThrAsn: 4.382 ± 0.14
1.844ThrPro: 1.844 ± 0.109
1.428ThrGln: 1.428 ± 0.087
1.749ThrArg: 1.749 ± 0.086
3.295ThrSer: 3.295 ± 0.11
2.547ThrThr: 2.547 ± 0.141
2.112ThrVal: 2.112 ± 0.093
0.417ThrTrp: 0.417 ± 0.034
2.468ThrTyr: 2.468 ± 0.088
0.0ThrXaa: 0.0 ± 0.0
Val
1.406ValAla: 1.406 ± 0.08
0.757ValCys: 0.757 ± 0.045
2.967ValAsp: 2.967 ± 0.111
2.961ValGlu: 2.961 ± 0.109
2.124ValPhe: 2.124 ± 0.092
2.0ValGly: 2.0 ± 0.133
0.731ValHis: 0.731 ± 0.051
4.048ValIle: 4.048 ± 0.112
4.722ValLys: 4.722 ± 0.186
3.263ValLeu: 3.263 ± 0.108
0.728ValMet: 0.728 ± 0.056
4.039ValAsn: 4.039 ± 0.199
1.714ValPro: 1.714 ± 0.087
1.237ValGln: 1.237 ± 0.071
1.45ValArg: 1.45 ± 0.08
3.158ValSer: 3.158 ± 0.132
3.113ValThr: 3.113 ± 0.205
2.713ValVal: 2.713 ± 0.129
0.347ValTrp: 0.347 ± 0.037
2.312ValTyr: 2.312 ± 0.094
0.0ValXaa: 0.0 ± 0.0
Trp
0.541TrpAla: 0.541 ± 0.066
0.213TrpCys: 0.213 ± 0.028
0.464TrpAsp: 0.464 ± 0.04
0.369TrpGlu: 0.369 ± 0.033
0.423TrpPhe: 0.423 ± 0.041
0.305TrpGly: 0.305 ± 0.039
0.118TrpHis: 0.118 ± 0.021
0.827TrpIle: 0.827 ± 0.058
0.766TrpLys: 0.766 ± 0.06
0.595TrpLeu: 0.595 ± 0.051
0.159TrpMet: 0.159 ± 0.025
0.76TrpAsn: 0.76 ± 0.055
0.143TrpPro: 0.143 ± 0.022
0.181TrpGln: 0.181 ± 0.026
0.245TrpArg: 0.245 ± 0.03
0.518TrpSer: 0.518 ± 0.04
0.436TrpThr: 0.436 ± 0.048
0.372TrpVal: 0.372 ± 0.045
0.35TrpTrp: 0.35 ± 0.081
0.467TrpTyr: 0.467 ± 0.049
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.914TyrAla: 1.914 ± 0.123
0.938TyrCys: 0.938 ± 0.059
3.937TyrAsp: 3.937 ± 0.111
2.802TyrGlu: 2.802 ± 0.099
3.59TyrPhe: 3.59 ± 0.118
2.725TyrGly: 2.725 ± 0.098
1.285TyrHis: 1.285 ± 0.071
5.117TyrIle: 5.117 ± 0.154
4.182TyrLys: 4.182 ± 0.154
6.532TyrLeu: 6.532 ± 0.229
0.957TyrMet: 0.957 ± 0.058
4.786TyrAsn: 4.786 ± 0.145
1.733TyrPro: 1.733 ± 0.078
1.739TyrGln: 1.739 ± 0.075
1.587TyrArg: 1.587 ± 0.084
3.504TyrSer: 3.504 ± 0.135
2.461TyrThr: 2.461 ± 0.101
2.468TyrVal: 2.468 ± 0.097
0.398TyrTrp: 0.398 ± 0.036
3.498TyrTyr: 3.498 ± 0.152
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 882 proteins (314460 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski