Amino acid dipepetide frequency for Carrot red leaf virus associated RNA

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
15.253AlaAla: 15.253 ± 7.924
1.907AlaCys: 1.907 ± 1.02
1.907AlaAsp: 1.907 ± 0.991
4.766AlaGlu: 4.766 ± 1.629
2.86AlaPhe: 2.86 ± 1.53
2.86AlaGly: 2.86 ± 0.69
1.907AlaHis: 1.907 ± 0.991
3.813AlaIle: 3.813 ± 2.04
10.486AlaLys: 10.486 ± 4.578
5.72AlaLeu: 5.72 ± 1.443
2.86AlaMet: 2.86 ± 2.547
4.766AlaAsn: 4.766 ± 1.629
1.907AlaPro: 1.907 ± 2.494
1.907AlaGln: 1.907 ± 0.991
4.766AlaArg: 4.766 ± 2.55
4.766AlaSer: 4.766 ± 2.06
4.766AlaThr: 4.766 ± 1.013
8.58AlaVal: 8.58 ± 2.782
0.953AlaTrp: 0.953 ± 0.51
1.907AlaTyr: 1.907 ± 0.991
0.0AlaXaa: 0.0 ± 0.0
Cys
2.86CysAla: 2.86 ± 2.803
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.953CysGlu: 0.953 ± 0.51
0.0CysPhe: 0.0 ± 0.0
2.86CysGly: 2.86 ± 0.69
0.953CysHis: 0.953 ± 2.742
3.813CysIle: 3.813 ± 1.981
0.953CysLys: 0.953 ± 0.51
3.813CysLeu: 3.813 ± 2.276
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.953CysGln: 0.953 ± 0.51
0.953CysArg: 0.953 ± 0.51
0.953CysSer: 0.953 ± 0.51
0.953CysThr: 0.953 ± 0.51
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.953CysTyr: 0.953 ± 0.51
0.0CysXaa: 0.0 ± 0.0
Asp
9.533AspAla: 9.533 ± 1.951
1.907AspCys: 1.907 ± 0.991
0.953AspAsp: 0.953 ± 0.51
4.766AspGlu: 4.766 ± 2.332
0.953AspPhe: 0.953 ± 0.51
2.86AspGly: 2.86 ± 2.332
0.0AspHis: 0.0 ± 0.0
0.953AspIle: 0.953 ± 0.51
0.953AspLys: 0.953 ± 0.51
3.813AspLeu: 3.813 ± 0.7
0.953AspMet: 0.953 ± 0.51
0.953AspAsn: 0.953 ± 0.51
1.907AspPro: 1.907 ± 1.02
1.907AspGln: 1.907 ± 1.02
1.907AspArg: 1.907 ± 2.494
2.86AspSer: 2.86 ± 1.53
3.813AspThr: 3.813 ± 2.276
3.813AspVal: 3.813 ± 0.7
0.0AspTrp: 0.0 ± 0.0
0.953AspTyr: 0.953 ± 0.51
0.0AspXaa: 0.0 ± 0.0
Glu
8.58GluAla: 8.58 ± 3.591
0.953GluCys: 0.953 ± 2.742
4.766GluAsp: 4.766 ± 1.629
3.813GluGlu: 3.813 ± 1.981
2.86GluPhe: 2.86 ± 1.53
2.86GluGly: 2.86 ± 1.53
0.953GluHis: 0.953 ± 0.51
3.813GluIle: 3.813 ± 2.406
3.813GluLys: 3.813 ± 2.04
4.766GluLeu: 4.766 ± 1.013
0.0GluMet: 0.0 ± 0.0
1.907GluAsn: 1.907 ± 0.991
1.907GluPro: 1.907 ± 1.02
0.0GluGln: 0.0 ± 0.0
5.72GluArg: 5.72 ± 1.379
2.86GluSer: 2.86 ± 1.53
1.907GluThr: 1.907 ± 1.02
9.533GluVal: 9.533 ± 3.258
1.907GluTrp: 1.907 ± 2.494
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
1.907PheAla: 1.907 ± 1.02
2.86PheCys: 2.86 ± 0.69
1.907PheAsp: 1.907 ± 1.02
0.953PheGlu: 0.953 ± 0.51
0.0PhePhe: 0.0 ± 0.0
2.86PheGly: 2.86 ± 1.53
0.953PheHis: 0.953 ± 0.51
2.86PheIle: 2.86 ± 0.69
0.953PheLys: 0.953 ± 0.51
2.86PheLeu: 2.86 ± 1.53
0.0PheMet: 0.0 ± 0.0
0.0PheAsn: 0.0 ± 0.0
0.953PhePro: 0.953 ± 0.51
0.953PheGln: 0.953 ± 0.51
0.953PheArg: 0.953 ± 0.51
2.86PheSer: 2.86 ± 1.53
3.813PheThr: 3.813 ± 2.04
0.953PheVal: 0.953 ± 0.51
0.0PheTrp: 0.0 ± 0.0
2.86PheTyr: 2.86 ± 1.53
0.0PheXaa: 0.0 ± 0.0
Gly
1.907GlyAla: 1.907 ± 1.02
0.0GlyCys: 0.0 ± 0.0
4.766GlyAsp: 4.766 ± 1.013
2.86GlyGlu: 2.86 ± 0.69
3.813GlyPhe: 3.813 ± 2.04
4.766GlyGly: 4.766 ± 4.801
0.0GlyHis: 0.0 ± 0.0
2.86GlyIle: 2.86 ± 2.332
0.953GlyLys: 0.953 ± 0.51
12.393GlyLeu: 12.393 ± 2.625
0.953GlyMet: 0.953 ± 0.51
2.86GlyAsn: 2.86 ± 2.332
2.86GlyPro: 2.86 ± 1.53
1.907GlyGln: 1.907 ± 0.991
3.813GlyArg: 3.813 ± 2.276
0.953GlySer: 0.953 ± 0.51
4.766GlyThr: 4.766 ± 1.629
4.766GlyVal: 4.766 ± 4.801
1.907GlyTrp: 1.907 ± 1.02
0.953GlyTyr: 0.953 ± 2.742
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.953HisCys: 0.953 ± 2.742
0.953HisAsp: 0.953 ± 2.742
0.953HisGlu: 0.953 ± 0.51
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.953HisIle: 0.953 ± 0.51
1.907HisLys: 1.907 ± 1.02
1.907HisLeu: 1.907 ± 0.991
1.907HisMet: 1.907 ± 0.991
3.813HisAsn: 3.813 ± 1.981
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
1.907HisVal: 1.907 ± 1.02
0.0HisTrp: 0.0 ± 0.0
0.953HisTyr: 0.953 ± 0.51
0.0HisXaa: 0.0 ± 0.0
Ile
1.907IleAla: 1.907 ± 0.991
0.953IleCys: 0.953 ± 0.51
3.813IleAsp: 3.813 ± 0.7
6.673IleGlu: 6.673 ± 1.912
0.953IlePhe: 0.953 ± 0.51
0.953IleGly: 0.953 ± 0.51
1.907IleHis: 1.907 ± 0.991
0.953IleIle: 0.953 ± 0.51
3.813IleLys: 3.813 ± 0.7
1.907IleLeu: 1.907 ± 1.02
1.907IleMet: 1.907 ± 1.02
4.766IleAsn: 4.766 ± 1.629
0.953IlePro: 0.953 ± 0.51
0.953IleGln: 0.953 ± 0.51
6.673IleArg: 6.673 ± 2.606
3.813IleSer: 3.813 ± 1.981
2.86IleThr: 2.86 ± 0.69
4.766IleVal: 4.766 ± 2.06
0.0IleTrp: 0.0 ± 0.0
1.907IleTyr: 1.907 ± 2.494
0.0IleXaa: 0.0 ± 0.0
Lys
3.813LysAla: 3.813 ± 2.276
0.0LysCys: 0.0 ± 0.0
3.813LysAsp: 3.813 ± 2.04
5.72LysGlu: 5.72 ± 1.443
4.766LysPhe: 4.766 ± 1.013
2.86LysGly: 2.86 ± 1.53
0.0LysHis: 0.0 ± 0.0
4.766LysIle: 4.766 ± 1.629
0.953LysLys: 0.953 ± 0.51
6.673LysLeu: 6.673 ± 2.606
0.953LysMet: 0.953 ± 1.15
0.953LysAsn: 0.953 ± 0.51
1.907LysPro: 1.907 ± 2.494
0.0LysGln: 0.0 ± 0.0
4.766LysArg: 4.766 ± 1.013
3.813LysSer: 3.813 ± 0.7
3.813LysThr: 3.813 ± 0.7
3.813LysVal: 3.813 ± 0.7
0.953LysTrp: 0.953 ± 0.51
1.907LysTyr: 1.907 ± 2.494
0.953LysXaa: 0.953 ± 0.51
Leu
8.58LeuAla: 8.58 ± 1.396
0.0LeuCys: 0.0 ± 0.0
2.86LeuAsp: 2.86 ± 1.53
7.626LeuGlu: 7.626 ± 1.401
0.0LeuPhe: 0.0 ± 0.0
7.626LeuGly: 7.626 ± 1.651
0.953LeuHis: 0.953 ± 0.51
6.673LeuIle: 6.673 ± 2.606
3.813LeuLys: 3.813 ± 2.04
2.86LeuLeu: 2.86 ± 0.69
3.813LeuMet: 3.813 ± 0.7
5.72LeuAsn: 5.72 ± 2.706
2.86LeuPro: 2.86 ± 0.69
0.0LeuGln: 0.0 ± 0.0
6.673LeuArg: 6.673 ± 1.293
7.626LeuSer: 7.626 ± 1.651
5.72LeuThr: 5.72 ± 1.443
7.626LeuVal: 7.626 ± 2.297
0.0LeuTrp: 0.0 ± 0.0
3.813LeuTyr: 3.813 ± 0.7
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.953MetCys: 0.953 ± 0.51
0.953MetAsp: 0.953 ± 2.742
3.813MetGlu: 3.813 ± 1.981
0.0MetPhe: 0.0 ± 0.0
3.813MetGly: 3.813 ± 1.981
0.0MetHis: 0.0 ± 0.0
2.86MetIle: 2.86 ± 0.69
0.0MetLys: 0.0 ± 0.0
2.86MetLeu: 2.86 ± 2.332
0.0MetMet: 0.0 ± 0.0
0.953MetAsn: 0.953 ± 0.51
0.0MetPro: 0.0 ± 0.0
0.953MetGln: 0.953 ± 0.51
0.953MetArg: 0.953 ± 0.51
3.813MetSer: 3.813 ± 0.7
1.907MetThr: 1.907 ± 0.991
0.953MetVal: 0.953 ± 0.51
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.813AsnAla: 3.813 ± 1.981
0.0AsnCys: 0.0 ± 0.0
1.907AsnAsp: 1.907 ± 2.494
1.907AsnGlu: 1.907 ± 0.991
0.0AsnPhe: 0.0 ± 0.0
0.953AsnGly: 0.953 ± 0.51
0.0AsnHis: 0.0 ± 0.0
3.813AsnIle: 3.813 ± 0.7
4.766AsnLys: 4.766 ± 1.629
4.766AsnLeu: 4.766 ± 1.013
0.953AsnMet: 0.953 ± 0.51
1.907AsnAsn: 1.907 ± 1.02
3.813AsnPro: 3.813 ± 1.981
0.953AsnGln: 0.953 ± 0.51
4.766AsnArg: 4.766 ± 1.013
2.86AsnSer: 2.86 ± 0.69
1.907AsnThr: 1.907 ± 0.991
0.953AsnVal: 0.953 ± 0.51
2.86AsnTrp: 2.86 ± 0.69
1.907AsnTyr: 1.907 ± 2.494
0.0AsnXaa: 0.0 ± 0.0
Pro
3.813ProAla: 3.813 ± 1.981
0.0ProCys: 0.0 ± 0.0
1.907ProAsp: 1.907 ± 1.02
0.953ProGlu: 0.953 ± 2.742
0.0ProPhe: 0.0 ± 0.0
7.626ProGly: 7.626 ± 1.794
0.953ProHis: 0.953 ± 2.742
3.813ProIle: 3.813 ± 2.04
2.86ProLys: 2.86 ± 2.803
4.766ProLeu: 4.766 ± 2.06
0.953ProMet: 0.953 ± 0.51
1.907ProAsn: 1.907 ± 0.991
0.953ProPro: 0.953 ± 0.51
0.0ProGln: 0.0 ± 0.0
4.766ProArg: 4.766 ± 1.013
4.766ProSer: 4.766 ± 5.113
4.766ProThr: 4.766 ± 1.629
6.673ProVal: 6.673 ± 3.57
0.953ProTrp: 0.953 ± 0.51
2.86ProTyr: 2.86 ± 0.69
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
0.0GlnGlu: 0.0 ± 0.0
1.907GlnPhe: 1.907 ± 0.991
0.0GlnGly: 0.0 ± 0.0
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
0.0GlnLys: 0.0 ± 0.0
2.86GlnLeu: 2.86 ± 1.53
1.907GlnMet: 1.907 ± 0.991
0.0GlnAsn: 0.0 ± 0.0
4.766GlnPro: 4.766 ± 1.629
0.953GlnGln: 0.953 ± 0.51
0.0GlnArg: 0.0 ± 0.0
1.907GlnSer: 1.907 ± 1.02
0.953GlnThr: 0.953 ± 0.51
4.766GlnVal: 4.766 ± 1.013
0.0GlnTrp: 0.0 ± 0.0
1.907GlnTyr: 1.907 ± 0.991
0.0GlnXaa: 0.0 ± 0.0
Arg
7.626ArgAla: 7.626 ± 1.401
1.907ArgCys: 1.907 ± 1.02
0.0ArgAsp: 0.0 ± 0.0
5.72ArgGlu: 5.72 ± 2.972
3.813ArgPhe: 3.813 ± 2.04
4.766ArgGly: 4.766 ± 4.801
2.86ArgHis: 2.86 ± 0.69
3.813ArgIle: 3.813 ± 0.7
3.813ArgLys: 3.813 ± 0.7
5.72ArgLeu: 5.72 ± 2.706
0.953ArgMet: 0.953 ± 1.865
0.953ArgAsn: 0.953 ± 0.51
5.72ArgPro: 5.72 ± 1.379
1.907ArgGln: 1.907 ± 0.991
2.86ArgArg: 2.86 ± 0.69
2.86ArgSer: 2.86 ± 1.53
7.626ArgThr: 7.626 ± 1.401
9.533ArgVal: 9.533 ± 1.951
0.953ArgTrp: 0.953 ± 0.51
1.907ArgTyr: 1.907 ± 1.02
0.0ArgXaa: 0.0 ± 0.0
Ser
2.86SerAla: 2.86 ± 1.53
0.953SerCys: 0.953 ± 2.742
2.86SerAsp: 2.86 ± 1.53
2.86SerGlu: 2.86 ± 1.53
6.673SerPhe: 6.673 ± 3.57
0.953SerGly: 0.953 ± 0.51
1.907SerHis: 1.907 ± 0.991
0.953SerIle: 0.953 ± 0.51
7.626SerLys: 7.626 ± 1.794
2.86SerLeu: 2.86 ± 1.53
0.953SerMet: 0.953 ± 0.51
2.86SerAsn: 2.86 ± 0.69
5.72SerPro: 5.72 ± 2.494
2.86SerGln: 2.86 ± 0.69
6.673SerArg: 6.673 ± 1.293
9.533SerSer: 9.533 ± 3.392
2.86SerThr: 2.86 ± 0.69
2.86SerVal: 2.86 ± 0.69
0.0SerTrp: 0.0 ± 0.0
2.86SerTyr: 2.86 ± 2.803
0.0SerXaa: 0.0 ± 0.0
Thr
2.86ThrAla: 2.86 ± 0.69
2.86ThrCys: 2.86 ± 0.69
4.766ThrAsp: 4.766 ± 1.013
0.0ThrGlu: 0.0 ± 0.0
1.907ThrPhe: 1.907 ± 1.02
4.766ThrGly: 4.766 ± 1.013
0.953ThrHis: 0.953 ± 0.51
2.86ThrIle: 2.86 ± 0.69
1.907ThrLys: 1.907 ± 1.02
3.813ThrLeu: 3.813 ± 1.981
0.0ThrMet: 0.0 ± 0.0
6.673ThrAsn: 6.673 ± 1.912
9.533ThrPro: 9.533 ± 2.277
2.86ThrGln: 2.86 ± 0.69
5.72ThrArg: 5.72 ± 1.443
5.72ThrSer: 5.72 ± 1.443
8.58ThrThr: 8.58 ± 1.396
0.953ThrVal: 0.953 ± 0.51
0.0ThrTrp: 0.0 ± 0.0
0.953ThrTyr: 0.953 ± 0.51
0.0ThrXaa: 0.0 ± 0.0
Val
5.72ValAla: 5.72 ± 1.443
4.766ValCys: 4.766 ± 1.013
4.766ValAsp: 4.766 ± 2.332
5.72ValGlu: 5.72 ± 1.379
0.953ValPhe: 0.953 ± 0.51
4.766ValGly: 4.766 ± 1.013
1.907ValHis: 1.907 ± 1.02
2.86ValIle: 2.86 ± 0.69
2.86ValLys: 2.86 ± 2.332
7.626ValLeu: 7.626 ± 1.401
3.813ValMet: 3.813 ± 1.981
2.86ValAsn: 2.86 ± 0.69
4.766ValPro: 4.766 ± 2.06
1.907ValGln: 1.907 ± 0.991
7.626ValArg: 7.626 ± 3.289
4.766ValSer: 4.766 ± 1.013
4.766ValThr: 4.766 ± 1.013
5.72ValVal: 5.72 ± 1.379
0.953ValTrp: 0.953 ± 0.51
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.953TrpAla: 0.953 ± 0.51
0.0TrpCys: 0.0 ± 0.0
0.953TrpAsp: 0.953 ± 0.51
0.953TrpGlu: 0.953 ± 0.51
0.0TrpPhe: 0.0 ± 0.0
0.953TrpGly: 0.953 ± 2.742
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
2.86TrpLys: 2.86 ± 1.53
1.907TrpLeu: 1.907 ± 0.991
0.0TrpMet: 0.0 ± 0.0
0.953TrpAsn: 0.953 ± 0.51
0.0TrpPro: 0.0 ± 0.0
0.953TrpGln: 0.953 ± 0.51
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
0.953TrpThr: 0.953 ± 0.51
0.0TrpVal: 0.0 ± 0.0
0.953TrpTrp: 0.953 ± 0.51
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
7.626TyrAla: 7.626 ± 1.794
0.0TyrCys: 0.0 ± 0.0
1.907TyrAsp: 1.907 ± 1.02
1.907TyrGlu: 1.907 ± 2.494
0.0TyrPhe: 0.0 ± 0.0
0.0TyrGly: 0.0 ± 0.0
0.0TyrHis: 0.0 ± 0.0
0.0TyrIle: 0.0 ± 0.0
1.907TyrLys: 1.907 ± 1.02
0.953TyrLeu: 0.953 ± 0.51
0.953TyrMet: 0.953 ± 0.51
0.0TyrAsn: 0.0 ± 0.0
4.766TyrPro: 4.766 ± 5.113
0.0TyrGln: 0.0 ± 0.0
5.72TyrArg: 5.72 ± 2.706
0.953TyrSer: 0.953 ± 0.51
0.953TyrThr: 0.953 ± 0.51
0.953TyrVal: 0.953 ± 0.51
0.0TyrTrp: 0.0 ± 0.0
0.953TyrTyr: 0.953 ± 2.742
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.953XaaGly: 0.953 ± 0.51
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1050 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski