Amino acid dipepetide frequency for Bacteroides graminisolvens DSM 19988 = JCM 15093

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.778AlaAla: 5.778 ± 0.096	0.962AlaCys: 0.962 ± 0.03	4.37AlaAsp: 4.37 ± 0.073	4.511AlaGlu: 4.511 ± 0.077	3.198AlaPhe: 3.198 ± 0.059	5.161AlaGly: 5.161 ± 0.083	1.278AlaHis: 1.278 ± 0.035	4.73AlaIle: 4.73 ± 0.075	4.309AlaLys: 4.309 ± 0.077	6.755AlaLeu: 6.755 ± 0.093	1.921AlaMet: 1.921 ± 0.046	3.446AlaAsn: 3.446 ± 0.059	2.238AlaPro: 2.238 ± 0.05	2.819AlaGln: 2.819 ± 0.055	3.004AlaArg: 3.004 ± 0.057	4.607AlaSer: 4.607 ± 0.072	3.93AlaThr: 3.93 ± 0.068	4.699AlaVal: 4.699 ± 0.08	0.803AlaTrp: 0.803 ± 0.027	2.967AlaTyr: 2.967 ± 0.05	0.0AlaXaa: 0.0 ± 0.0
Cys	0.728CysAla: 0.728 ± 0.026	0.208CysCys: 0.208 ± 0.015	0.647CysAsp: 0.647 ± 0.025	0.645CysGlu: 0.645 ± 0.027	0.631CysPhe: 0.631 ± 0.026	0.963CysGly: 0.963 ± 0.031	0.257CysHis: 0.257 ± 0.015	0.87CysIle: 0.87 ± 0.03	0.721CysLys: 0.721 ± 0.027	1.023CysLeu: 1.023 ± 0.031	0.338CysMet: 0.338 ± 0.017	0.583CysAsn: 0.583 ± 0.025	0.477CysPro: 0.477 ± 0.025	0.323CysGln: 0.323 ± 0.016	0.549CysArg: 0.549 ± 0.024	0.791CysSer: 0.791 ± 0.023	0.599CysThr: 0.599 ± 0.025	0.725CysVal: 0.725 ± 0.029	0.151CysTrp: 0.151 ± 0.011	0.498CysTyr: 0.498 ± 0.025	0.0CysXaa: 0.0 ± 0.0
Asp	4.02AspAla: 4.02 ± 0.06	0.598AspCys: 0.598 ± 0.026	2.639AspAsp: 2.639 ± 0.059	3.744AspGlu: 3.744 ± 0.061	2.974AspPhe: 2.974 ± 0.051	3.945AspGly: 3.945 ± 0.068	0.857AspHis: 0.857 ± 0.034	3.787AspIle: 3.787 ± 0.06	4.066AspLys: 4.066 ± 0.063	4.583AspLeu: 4.583 ± 0.068	1.548AspMet: 1.548 ± 0.04	2.798AspAsn: 2.798 ± 0.054	1.849AspPro: 1.849 ± 0.043	1.369AspGln: 1.369 ± 0.04	2.172AspArg: 2.172 ± 0.048	3.301AspSer: 3.301 ± 0.058	2.568AspThr: 2.568 ± 0.046	3.746AspVal: 3.746 ± 0.061	0.788AspTrp: 0.788 ± 0.025	2.737AspTyr: 2.737 ± 0.059	0.0AspXaa: 0.0 ± 0.0
Glu	4.692GluAla: 4.692 ± 0.085	0.545GluCys: 0.545 ± 0.024	2.998GluAsp: 2.998 ± 0.062	4.815GluGlu: 4.815 ± 0.093	2.603GluPhe: 2.603 ± 0.054	3.908GluGly: 3.908 ± 0.061	1.182GluHis: 1.182 ± 0.032	4.551GluIle: 4.551 ± 0.083	5.07GluLys: 5.07 ± 0.075	6.321GluLeu: 6.321 ± 0.087	2.026GluMet: 2.026 ± 0.045	3.445GluAsn: 3.445 ± 0.061	1.654GluPro: 1.654 ± 0.041	2.44GluGln: 2.44 ± 0.051	2.931GluArg: 2.931 ± 0.055	3.315GluSer: 3.315 ± 0.056	3.235GluThr: 3.235 ± 0.055	4.35GluVal: 4.35 ± 0.071	0.821GluTrp: 0.821 ± 0.029	2.638GluTyr: 2.638 ± 0.055	0.0GluXaa: 0.0 ± 0.0
Phe	3.118PheAla: 3.118 ± 0.054	0.609PheCys: 0.609 ± 0.023	2.734PheAsp: 2.734 ± 0.051	2.541PheGlu: 2.541 ± 0.051	2.208PhePhe: 2.208 ± 0.059	3.255PheGly: 3.255 ± 0.064	0.821PheHis: 0.821 ± 0.027	3.274PheIle: 3.274 ± 0.07	2.623PheLys: 2.623 ± 0.046	4.058PheLeu: 4.058 ± 0.079	1.341PheMet: 1.341 ± 0.036	2.537PheAsn: 2.537 ± 0.053	1.655PhePro: 1.655 ± 0.039	1.387PheGln: 1.387 ± 0.036	2.017PheArg: 2.017 ± 0.043	3.552PheSer: 3.552 ± 0.067	2.737PheThr: 2.737 ± 0.055	2.971PheVal: 2.971 ± 0.049	0.618PheTrp: 0.618 ± 0.026	1.867PheTyr: 1.867 ± 0.044	0.0PheXaa: 0.0 ± 0.0
Gly	4.44GlyAla: 4.44 ± 0.078	0.852GlyCys: 0.852 ± 0.031	3.456GlyAsp: 3.456 ± 0.058	3.859GlyGlu: 3.859 ± 0.07	3.172GlyPhe: 3.172 ± 0.056	4.844GlyGly: 4.844 ± 0.087	1.239GlyHis: 1.239 ± 0.036	5.216GlyIle: 5.216 ± 0.069	5.137GlyLys: 5.137 ± 0.073	5.864GlyLeu: 5.864 ± 0.075	2.063GlyMet: 2.063 ± 0.045	3.627GlyAsn: 3.627 ± 0.07	1.352GlyPro: 1.352 ± 0.036	2.085GlyGln: 2.085 ± 0.04	2.784GlyArg: 2.784 ± 0.058	4.27GlySer: 4.27 ± 0.07	4.213GlyThr: 4.213 ± 0.068	5.037GlyVal: 5.037 ± 0.082	1.013GlyTrp: 1.013 ± 0.033	3.322GlyTyr: 3.322 ± 0.06	0.0GlyXaa: 0.0 ± 0.0
His	1.242HisAla: 1.242 ± 0.036	0.278HisCys: 0.278 ± 0.017	0.871HisAsp: 0.871 ± 0.031	0.999HisGlu: 0.999 ± 0.033	1.03HisPhe: 1.03 ± 0.03	1.176HisGly: 1.176 ± 0.036	0.477HisHis: 0.477 ± 0.021	1.395HisIle: 1.395 ± 0.043	1.122HisLys: 1.122 ± 0.034	1.771HisLeu: 1.771 ± 0.042	0.36HisMet: 0.36 ± 0.016	0.94HisAsn: 0.94 ± 0.033	0.971HisPro: 0.971 ± 0.028	0.629HisGln: 0.629 ± 0.022	0.819HisArg: 0.819 ± 0.03	1.135HisSer: 1.135 ± 0.033	1.032HisThr: 1.032 ± 0.029	1.069HisVal: 1.069 ± 0.031	0.248HisTrp: 0.248 ± 0.016	0.901HisTyr: 0.901 ± 0.029	0.0HisXaa: 0.0 ± 0.0
Ile	5.202IleAla: 5.202 ± 0.064	0.903IleCys: 0.903 ± 0.029	4.314IleAsp: 4.314 ± 0.071	4.474IleGlu: 4.474 ± 0.068	2.676IlePhe: 2.676 ± 0.052	4.593IleGly: 4.593 ± 0.072	1.304IleHis: 1.304 ± 0.034	4.669IleIle: 4.669 ± 0.08	4.517IleLys: 4.517 ± 0.07	5.843IleLeu: 5.843 ± 0.094	1.489IleMet: 1.489 ± 0.044	3.663IleAsn: 3.663 ± 0.066	3.058IlePro: 3.058 ± 0.049	2.254IleGln: 2.254 ± 0.053	3.266IleArg: 3.266 ± 0.058	4.824IleSer: 4.824 ± 0.073	4.193IleThr: 4.193 ± 0.059	4.31IleVal: 4.31 ± 0.068	0.768IleTrp: 0.768 ± 0.028	2.796IleTyr: 2.796 ± 0.06	0.0IleXaa: 0.0 ± 0.0
Lys	4.923LysAla: 4.923 ± 0.078	0.536LysCys: 0.536 ± 0.02	4.008LysAsp: 4.008 ± 0.064	6.04LysGlu: 6.04 ± 0.078	2.183LysPhe: 2.183 ± 0.041	4.853LysGly: 4.853 ± 0.073	1.244LysHis: 1.244 ± 0.036	4.302LysIle: 4.302 ± 0.07	5.294LysLys: 5.294 ± 0.093	5.842LysLeu: 5.842 ± 0.082	2.156LysMet: 2.156 ± 0.042	3.78LysAsn: 3.78 ± 0.064	2.11LysPro: 2.11 ± 0.043	2.725LysGln: 2.725 ± 0.052	3.07LysArg: 3.07 ± 0.061	3.746LysSer: 3.746 ± 0.06	3.662LysThr: 3.662 ± 0.062	4.356LysVal: 4.356 ± 0.073	0.795LysTrp: 0.795 ± 0.025	3.041LysTyr: 3.041 ± 0.05	0.0LysXaa: 0.0 ± 0.0
Leu	6.528LeuAla: 6.528 ± 0.078	1.241LeuCys: 1.241 ± 0.035	4.278LeuAsp: 4.278 ± 0.065	4.871LeuGlu: 4.871 ± 0.074	4.709LeuPhe: 4.709 ± 0.088	5.472LeuGly: 5.472 ± 0.084	1.72LeuHis: 1.72 ± 0.043	5.981LeuIle: 5.981 ± 0.093	6.752LeuLys: 6.752 ± 0.088	9.006LeuLeu: 9.006 ± 0.124	2.468LeuMet: 2.468 ± 0.042	5.153LeuAsn: 5.153 ± 0.08	4.06LeuPro: 4.06 ± 0.062	3.336LeuGln: 3.336 ± 0.07	4.016LeuArg: 4.016 ± 0.063	6.912LeuSer: 6.912 ± 0.092	5.339LeuThr: 5.339 ± 0.074	5.332LeuVal: 5.332 ± 0.076	1.072LeuTrp: 1.072 ± 0.033	3.619LeuTyr: 3.619 ± 0.061	0.0LeuXaa: 0.0 ± 0.0
Met	2.088MetAla: 2.088 ± 0.047	0.263MetCys: 0.263 ± 0.015	1.45MetAsp: 1.45 ± 0.039	1.748MetGlu: 1.748 ± 0.04	1.027MetPhe: 1.027 ± 0.031	1.868MetGly: 1.868 ± 0.04	0.513MetHis: 0.513 ± 0.024	1.682MetIle: 1.682 ± 0.044	2.471MetLys: 2.471 ± 0.039	2.452MetLeu: 2.452 ± 0.052	0.793MetMet: 0.793 ± 0.029	1.675MetAsn: 1.675 ± 0.043	1.158MetPro: 1.158 ± 0.036	1.09MetGln: 1.09 ± 0.032	1.233MetArg: 1.233 ± 0.035	1.577MetSer: 1.577 ± 0.033	1.427MetThr: 1.427 ± 0.036	1.594MetVal: 1.594 ± 0.038	0.297MetTrp: 0.297 ± 0.015	0.878MetTyr: 0.878 ± 0.031	0.0MetXaa: 0.0 ± 0.0
Asn	3.587AsnAla: 3.587 ± 0.062	0.533AsnCys: 0.533 ± 0.022	2.739AsnAsp: 2.739 ± 0.05	3.315AsnGlu: 3.315 ± 0.059	2.331AsnPhe: 2.331 ± 0.052	4.086AsnGly: 4.086 ± 0.068	1.037AsnHis: 1.037 ± 0.031	3.842AsnIle: 3.842 ± 0.07	3.775AsnLys: 3.775 ± 0.062	4.657AsnLeu: 4.657 ± 0.065	1.421AsnMet: 1.421 ± 0.034	2.969AsnAsn: 2.969 ± 0.068	2.496AsnPro: 2.496 ± 0.052	1.854AsnGln: 1.854 ± 0.039	2.375AsnArg: 2.375 ± 0.052	3.214AsnSer: 3.214 ± 0.062	2.831AsnThr: 2.831 ± 0.058	3.28AsnVal: 3.28 ± 0.062	0.711AsnTrp: 0.711 ± 0.028	2.538AsnTyr: 2.538 ± 0.053	0.0AsnXaa: 0.0 ± 0.0
Pro	2.738ProAla: 2.738 ± 0.059	0.348ProCys: 0.348 ± 0.019	2.402ProAsp: 2.402 ± 0.053	2.906ProGlu: 2.906 ± 0.052	1.786ProPhe: 1.786 ± 0.04	2.406ProGly: 2.406 ± 0.053	0.742ProHis: 0.742 ± 0.026	2.304ProIle: 2.304 ± 0.056	1.864ProLys: 1.864 ± 0.037	3.297ProLeu: 3.297 ± 0.056	0.936ProMet: 0.936 ± 0.037	1.653ProAsn: 1.653 ± 0.043	0.758ProPro: 0.758 ± 0.03	1.518ProGln: 1.518 ± 0.04	1.31ProArg: 1.31 ± 0.036	2.272ProSer: 2.272 ± 0.044	1.86ProThr: 1.86 ± 0.045	2.941ProVal: 2.941 ± 0.056	0.451ProTrp: 0.451 ± 0.022	1.653ProTyr: 1.653 ± 0.04	0.0ProXaa: 0.0 ± 0.0
Gln	2.489GlnAla: 2.489 ± 0.047	0.297GlnCys: 0.297 ± 0.016	1.525GlnAsp: 1.525 ± 0.038	2.292GlnGlu: 2.292 ± 0.05	1.363GlnPhe: 1.363 ± 0.036	1.994GlnGly: 1.994 ± 0.04	0.661GlnHis: 0.661 ± 0.027	2.508GlnIle: 2.508 ± 0.049	2.584GlnLys: 2.584 ± 0.052	3.46GlnLeu: 3.46 ± 0.073	1.051GlnMet: 1.051 ± 0.037	1.842GlnAsn: 1.842 ± 0.05	1.183GlnPro: 1.183 ± 0.033	1.636GlnGln: 1.636 ± 0.047	1.612GlnArg: 1.612 ± 0.038	2.071GlnSer: 2.071 ± 0.046	2.112GlnThr: 2.112 ± 0.042	2.275GlnVal: 2.275 ± 0.053	0.498GlnTrp: 0.498 ± 0.021	1.467GlnTyr: 1.467 ± 0.043	0.0GlnXaa: 0.0 ± 0.0
Arg	2.673ArgAla: 2.673 ± 0.05	0.465ArgCys: 0.465 ± 0.022	2.076ArgAsp: 2.076 ± 0.047	2.685ArgGlu: 2.685 ± 0.048	2.21ArgPhe: 2.21 ± 0.046	2.357ArgGly: 2.357 ± 0.049	0.778ArgHis: 0.778 ± 0.028	3.443ArgIle: 3.443 ± 0.052	3.372ArgLys: 3.372 ± 0.058	4.177ArgLeu: 4.177 ± 0.059	1.523ArgMet: 1.523 ± 0.039	2.415ArgAsn: 2.415 ± 0.05	1.479ArgPro: 1.479 ± 0.048	1.563ArgGln: 1.563 ± 0.04	1.921ArgArg: 1.921 ± 0.047	2.414ArgSer: 2.414 ± 0.048	2.315ArgThr: 2.315 ± 0.05	2.681ArgVal: 2.681 ± 0.05	0.627ArgTrp: 0.627 ± 0.025	2.047ArgTyr: 2.047 ± 0.046	0.0ArgXaa: 0.0 ± 0.0
Ser	4.48SerAla: 4.48 ± 0.07	0.836SerCys: 0.836 ± 0.031	3.254SerAsp: 3.254 ± 0.06	3.709SerGlu: 3.709 ± 0.064	3.572SerPhe: 3.572 ± 0.059	4.65SerGly: 4.65 ± 0.07	1.155SerHis: 1.155 ± 0.034	4.629SerIle: 4.629 ± 0.072	3.876SerLys: 3.876 ± 0.056	6.313SerLeu: 6.313 ± 0.085	1.547SerMet: 1.547 ± 0.037	3.075SerAsn: 3.075 ± 0.066	2.295SerPro: 2.295 ± 0.05	2.005SerGln: 2.005 ± 0.043	2.618SerArg: 2.618 ± 0.053	4.385SerSer: 4.385 ± 0.084	3.382SerThr: 3.382 ± 0.064	4.509SerVal: 4.509 ± 0.067	0.862SerTrp: 0.862 ± 0.03	2.938SerTyr: 2.938 ± 0.062	0.0SerXaa: 0.0 ± 0.0
Thr	4.171ThrAla: 4.171 ± 0.069	0.565ThrCys: 0.565 ± 0.027	3.485ThrAsp: 3.485 ± 0.059	3.245ThrGlu: 3.245 ± 0.062	2.598ThrPhe: 2.598 ± 0.048	4.339ThrGly: 4.339 ± 0.07	0.995ThrHis: 0.995 ± 0.03	3.731ThrIle: 3.731 ± 0.059	2.962ThrLys: 2.962 ± 0.057	5.352ThrLeu: 5.352 ± 0.073	1.148ThrMet: 1.148 ± 0.034	2.803ThrAsn: 2.803 ± 0.056	2.618ThrPro: 2.618 ± 0.048	1.744ThrGln: 1.744 ± 0.04	2.164ThrArg: 2.164 ± 0.044	3.466ThrSer: 3.466 ± 0.055	3.167ThrThr: 3.167 ± 0.062	3.945ThrVal: 3.945 ± 0.065	0.648ThrTrp: 0.648 ± 0.027	2.509ThrTyr: 2.509 ± 0.053	0.0ThrXaa: 0.0 ± 0.0
Val	4.753ValAla: 4.753 ± 0.077	0.987ValCys: 0.987 ± 0.031	3.729ValAsp: 3.729 ± 0.059	4.022ValGlu: 4.022 ± 0.066	2.97ValPhe: 2.97 ± 0.055	4.071ValGly: 4.071 ± 0.06	1.102ValHis: 1.102 ± 0.031	4.683ValIle: 4.683 ± 0.071	4.374ValLys: 4.374 ± 0.071	5.974ValLeu: 5.974 ± 0.074	1.67ValMet: 1.67 ± 0.041	3.612ValAsn: 3.612 ± 0.061	2.589ValPro: 2.589 ± 0.052	2.013ValGln: 2.013 ± 0.042	2.779ValArg: 2.779 ± 0.044	4.599ValSer: 4.599 ± 0.063	3.839ValThr: 3.839 ± 0.067	4.737ValVal: 4.737 ± 0.077	0.725ValTrp: 0.725 ± 0.022	2.7ValTyr: 2.7 ± 0.059	0.0ValXaa: 0.0 ± 0.0
Trp	0.84TrpAla: 0.84 ± 0.028	0.171TrpCys: 0.171 ± 0.014	0.698TrpAsp: 0.698 ± 0.027	0.763TrpGlu: 0.763 ± 0.029	0.57TrpPhe: 0.57 ± 0.024	0.96TrpGly: 0.96 ± 0.035	0.248TrpHis: 0.248 ± 0.017	0.797TrpIle: 0.797 ± 0.03	0.912TrpLys: 0.912 ± 0.032	1.154TrpLeu: 1.154 ± 0.032	0.447TrpMet: 0.447 ± 0.021	0.841TrpAsn: 0.841 ± 0.029	0.321TrpPro: 0.321 ± 0.019	0.51TrpGln: 0.51 ± 0.022	0.534TrpArg: 0.534 ± 0.024	0.755TrpSer: 0.755 ± 0.032	0.642TrpThr: 0.642 ± 0.026	0.776TrpVal: 0.776 ± 0.029	0.227TrpTrp: 0.227 ± 0.015	0.519TrpTyr: 0.519 ± 0.023	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.999TyrAla: 2.999 ± 0.054	0.529TyrCys: 0.529 ± 0.022	2.414TyrAsp: 2.414 ± 0.053	2.354TyrGlu: 2.354 ± 0.05	2.113TyrPhe: 2.113 ± 0.053	2.941TyrGly: 2.941 ± 0.066	0.854TyrHis: 0.854 ± 0.03	2.72TyrIle: 2.72 ± 0.051	2.866TyrLys: 2.866 ± 0.056	3.961TyrLeu: 3.961 ± 0.066	1.037TyrMet: 1.037 ± 0.032	2.733TyrAsn: 2.733 ± 0.062	1.824TyrPro: 1.824 ± 0.041	1.625TyrGln: 1.625 ± 0.042	2.049TyrArg: 2.049 ± 0.041	2.883TyrSer: 2.883 ± 0.067	2.575TyrThr: 2.575 ± 0.048	2.596TyrVal: 2.596 ± 0.048	0.563TyrTrp: 0.563 ± 0.025	2.122TyrTyr: 2.122 ± 0.054	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3344 proteins (1078488 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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