Amino acid dipepetide frequency for Human adenovirus 56

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.098AlaAla: 8.098 ± 1.624
0.99AlaCys: 0.99 ± 0.316
2.969AlaAsp: 2.969 ± 0.43
3.689AlaGlu: 3.689 ± 0.649
2.969AlaPhe: 2.969 ± 0.327
5.219AlaGly: 5.219 ± 0.649
1.89AlaHis: 1.89 ± 0.437
2.519AlaIle: 2.519 ± 0.547
2.159AlaLys: 2.159 ± 0.449
7.468AlaLeu: 7.468 ± 1.322
1.35AlaMet: 1.35 ± 0.331
2.429AlaAsn: 2.429 ± 0.545
5.309AlaPro: 5.309 ± 0.746
2.339AlaGln: 2.339 ± 0.415
5.938AlaArg: 5.938 ± 0.896
4.949AlaSer: 4.949 ± 0.663
4.139AlaThr: 4.139 ± 0.669
4.949AlaVal: 4.949 ± 0.654
0.54AlaTrp: 0.54 ± 0.204
2.339AlaTyr: 2.339 ± 0.445
0.0AlaXaa: 0.0 ± 0.0
Cys
0.9CysAla: 0.9 ± 0.293
1.08CysCys: 1.08 ± 0.276
0.99CysAsp: 0.99 ± 0.292
1.08CysGlu: 1.08 ± 0.244
0.54CysPhe: 0.54 ± 0.232
1.71CysGly: 1.71 ± 0.422
0.63CysHis: 0.63 ± 0.234
0.45CysIle: 0.45 ± 0.274
0.81CysLys: 0.81 ± 0.263
1.26CysLeu: 1.26 ± 0.306
0.72CysMet: 0.72 ± 0.284
1.35CysAsn: 1.35 ± 0.444
1.08CysPro: 1.08 ± 0.348
0.45CysGln: 0.45 ± 0.183
1.26CysArg: 1.26 ± 0.413
1.17CysSer: 1.17 ± 0.39
1.17CysThr: 1.17 ± 0.329
1.08CysVal: 1.08 ± 0.339
0.63CysTrp: 0.63 ± 0.27
1.44CysTyr: 1.44 ± 0.346
0.0CysXaa: 0.0 ± 0.0
Asp
3.509AspAla: 3.509 ± 0.511
0.99AspCys: 0.99 ± 0.277
2.429AspAsp: 2.429 ± 0.59
5.489AspGlu: 5.489 ± 0.757
2.159AspPhe: 2.159 ± 0.433
3.509AspGly: 3.509 ± 0.865
1.17AspHis: 1.17 ± 0.345
2.069AspIle: 2.069 ± 0.386
2.069AspLys: 2.069 ± 0.38
5.489AspLeu: 5.489 ± 1.066
1.89AspMet: 1.89 ± 0.386
1.26AspAsn: 1.26 ± 0.338
3.599AspPro: 3.599 ± 0.471
1.17AspGln: 1.17 ± 0.31
3.599AspArg: 3.599 ± 0.724
3.959AspSer: 3.959 ± 0.609
2.789AspThr: 2.789 ± 0.544
3.239AspVal: 3.239 ± 0.381
0.63AspTrp: 0.63 ± 0.197
1.89AspTyr: 1.89 ± 0.409
0.0AspXaa: 0.0 ± 0.0
Glu
3.419GluAla: 3.419 ± 0.582
1.17GluCys: 1.17 ± 0.336
4.589GluAsp: 4.589 ± 1.1
8.638GluGlu: 8.638 ± 1.763
1.71GluPhe: 1.71 ± 0.348
4.049GluGly: 4.049 ± 0.68
1.53GluHis: 1.53 ± 0.405
2.699GluIle: 2.699 ± 0.561
2.609GluLys: 2.609 ± 0.491
6.928GluLeu: 6.928 ± 1.101
1.8GluMet: 1.8 ± 0.41
2.609GluAsn: 2.609 ± 0.553
2.789GluPro: 2.789 ± 0.389
3.419GluGln: 3.419 ± 0.644
4.949GluArg: 4.949 ± 0.735
3.419GluSer: 3.419 ± 0.715
3.779GluThr: 3.779 ± 0.703
3.239GluVal: 3.239 ± 0.49
0.9GluTrp: 0.9 ± 0.358
1.53GluTyr: 1.53 ± 0.43
0.0GluXaa: 0.0 ± 0.0
Phe
2.879PheAla: 2.879 ± 0.553
0.99PheCys: 0.99 ± 0.337
2.339PheAsp: 2.339 ± 0.604
2.069PheGlu: 2.069 ± 0.388
1.89PhePhe: 1.89 ± 0.414
0.99PheGly: 0.99 ± 0.263
1.08PheHis: 1.08 ± 0.341
1.44PheIle: 1.44 ± 0.332
1.53PheLys: 1.53 ± 0.369
3.509PheLeu: 3.509 ± 0.671
1.71PheMet: 1.71 ± 0.324
2.159PheAsn: 2.159 ± 0.462
2.339PhePro: 2.339 ± 0.395
1.71PheGln: 1.71 ± 0.319
2.249PheArg: 2.249 ± 0.512
3.329PheSer: 3.329 ± 0.519
2.249PheThr: 2.249 ± 0.422
2.609PheVal: 2.609 ± 0.364
0.09PheTrp: 0.09 ± 0.107
1.26PheTyr: 1.26 ± 0.409
0.0PheXaa: 0.0 ± 0.0
Gly
4.319GlyAla: 4.319 ± 0.571
1.71GlyCys: 1.71 ± 0.484
2.969GlyAsp: 2.969 ± 0.543
3.869GlyGlu: 3.869 ± 0.558
2.699GlyPhe: 2.699 ± 0.469
5.489GlyGly: 5.489 ± 0.777
1.53GlyHis: 1.53 ± 0.385
2.339GlyIle: 2.339 ± 0.373
2.159GlyLys: 2.159 ± 0.682
6.028GlyLeu: 6.028 ± 0.756
1.26GlyMet: 1.26 ± 0.346
2.699GlyAsn: 2.699 ± 0.801
3.059GlyPro: 3.059 ± 0.482
2.429GlyGln: 2.429 ± 0.61
5.219GlyArg: 5.219 ± 0.583
3.959GlySer: 3.959 ± 0.68
3.869GlyThr: 3.869 ± 0.567
5.219GlyVal: 5.219 ± 0.81
0.81GlyTrp: 0.81 ± 0.233
2.069GlyTyr: 2.069 ± 0.358
0.0GlyXaa: 0.0 ± 0.0
His
2.159HisAla: 2.159 ± 0.489
0.99HisCys: 0.99 ± 0.337
1.26HisAsp: 1.26 ± 0.37
1.35HisGlu: 1.35 ± 0.387
0.72HisPhe: 0.72 ± 0.276
1.89HisGly: 1.89 ± 0.406
0.54HisHis: 0.54 ± 0.183
1.17HisIle: 1.17 ± 0.286
0.72HisLys: 0.72 ± 0.367
2.339HisLeu: 2.339 ± 0.506
0.36HisMet: 0.36 ± 0.201
0.9HisAsn: 0.9 ± 0.291
2.429HisPro: 2.429 ± 0.635
0.81HisGln: 0.81 ± 0.272
2.429HisArg: 2.429 ± 0.447
1.44HisSer: 1.44 ± 0.291
1.35HisThr: 1.35 ± 0.293
1.62HisVal: 1.62 ± 0.35
0.54HisTrp: 0.54 ± 0.229
0.63HisTyr: 0.63 ± 0.224
0.0HisXaa: 0.0 ± 0.0
Ile
3.329IleAla: 3.329 ± 0.49
1.08IleCys: 1.08 ± 0.277
1.53IleAsp: 1.53 ± 0.411
1.53IleGlu: 1.53 ± 0.426
1.62IlePhe: 1.62 ± 0.413
1.8IleGly: 1.8 ± 0.432
0.72IleHis: 0.72 ± 0.319
1.89IleIle: 1.89 ± 0.51
2.519IleLys: 2.519 ± 0.553
4.139IleLeu: 4.139 ± 0.705
1.53IleMet: 1.53 ± 0.347
1.89IleAsn: 1.89 ± 0.454
2.519IlePro: 2.519 ± 0.617
1.35IleGln: 1.35 ± 0.332
1.89IleArg: 1.89 ± 0.431
1.8IleSer: 1.8 ± 0.408
1.979IleThr: 1.979 ± 0.475
2.969IleVal: 2.969 ± 0.486
0.45IleTrp: 0.45 ± 0.165
1.44IleTyr: 1.44 ± 0.314
0.0IleXaa: 0.0 ± 0.0
Lys
2.339LysAla: 2.339 ± 0.511
0.81LysCys: 0.81 ± 0.263
1.979LysAsp: 1.979 ± 0.521
1.979LysGlu: 1.979 ± 0.436
1.979LysPhe: 1.979 ± 0.376
2.609LysGly: 2.609 ± 0.515
0.81LysHis: 0.81 ± 0.214
2.699LysIle: 2.699 ± 0.448
2.789LysLys: 2.789 ± 0.494
3.689LysLeu: 3.689 ± 0.685
1.17LysMet: 1.17 ± 0.361
1.8LysAsn: 1.8 ± 0.302
1.71LysPro: 1.71 ± 0.448
1.53LysGln: 1.53 ± 0.428
3.149LysArg: 3.149 ± 0.65
1.979LysSer: 1.979 ± 0.397
1.53LysThr: 1.53 ± 0.463
2.609LysVal: 2.609 ± 0.557
0.27LysTrp: 0.27 ± 0.165
1.26LysTyr: 1.26 ± 0.401
0.0LysXaa: 0.0 ± 0.0
Leu
6.928LeuAla: 6.928 ± 1.061
1.17LeuCys: 1.17 ± 0.338
4.679LeuAsp: 4.679 ± 0.745
5.669LeuGlu: 5.669 ± 1.089
2.699LeuPhe: 2.699 ± 0.497
5.309LeuGly: 5.309 ± 0.651
3.689LeuHis: 3.689 ± 0.762
2.879LeuIle: 2.879 ± 0.589
4.229LeuLys: 4.229 ± 0.852
9.538LeuLeu: 9.538 ± 0.994
3.509LeuMet: 3.509 ± 0.521
4.049LeuAsn: 4.049 ± 0.622
6.298LeuPro: 6.298 ± 0.88
5.309LeuGln: 5.309 ± 0.552
7.018LeuArg: 7.018 ± 0.664
5.489LeuSer: 5.489 ± 0.602
6.388LeuThr: 6.388 ± 0.772
6.658LeuVal: 6.658 ± 0.932
1.71LeuTrp: 1.71 ± 0.339
2.699LeuTyr: 2.699 ± 0.617
0.0LeuXaa: 0.0 ± 0.0
Met
2.609MetAla: 2.609 ± 0.395
0.81MetCys: 0.81 ± 0.237
1.979MetAsp: 1.979 ± 0.403
1.53MetGlu: 1.53 ± 0.313
0.54MetPhe: 0.54 ± 0.218
1.89MetGly: 1.89 ± 0.355
0.63MetHis: 0.63 ± 0.237
1.17MetIle: 1.17 ± 0.316
0.99MetLys: 0.99 ± 0.286
2.519MetLeu: 2.519 ± 0.412
0.45MetMet: 0.45 ± 0.219
1.44MetAsn: 1.44 ± 0.413
2.159MetPro: 2.159 ± 0.383
1.44MetGln: 1.44 ± 0.361
1.89MetArg: 1.89 ± 0.425
1.71MetSer: 1.71 ± 0.314
1.35MetThr: 1.35 ± 0.322
1.35MetVal: 1.35 ± 0.287
0.36MetTrp: 0.36 ± 0.206
1.17MetTyr: 1.17 ± 0.22
0.0MetXaa: 0.0 ± 0.0
Asn
2.249AsnAla: 2.249 ± 0.516
0.36AsnCys: 0.36 ± 0.142
2.429AsnAsp: 2.429 ± 0.472
2.069AsnGlu: 2.069 ± 0.349
2.429AsnPhe: 2.429 ± 0.491
2.429AsnGly: 2.429 ± 0.524
1.08AsnHis: 1.08 ± 0.381
2.609AsnIle: 2.609 ± 0.539
1.53AsnLys: 1.53 ± 0.364
4.409AsnLeu: 4.409 ± 0.749
1.979AsnMet: 1.979 ± 0.642
1.62AsnAsn: 1.62 ± 0.481
2.609AsnPro: 2.609 ± 0.425
1.62AsnGln: 1.62 ± 0.387
2.429AsnArg: 2.429 ± 0.415
2.429AsnSer: 2.429 ± 0.553
1.8AsnThr: 1.8 ± 0.566
2.609AsnVal: 2.609 ± 0.707
0.99AsnTrp: 0.99 ± 0.334
2.159AsnTyr: 2.159 ± 0.368
0.0AsnXaa: 0.0 ± 0.0
Pro
5.399ProAla: 5.399 ± 0.812
1.08ProCys: 1.08 ± 0.473
3.329ProAsp: 3.329 ± 0.506
4.499ProGlu: 4.499 ± 0.646
3.059ProPhe: 3.059 ± 0.458
4.589ProGly: 4.589 ± 0.568
1.35ProHis: 1.35 ± 0.32
1.71ProIle: 1.71 ± 0.365
2.069ProLys: 2.069 ± 0.484
4.679ProLeu: 4.679 ± 0.684
1.08ProMet: 1.08 ± 0.384
2.789ProAsn: 2.789 ± 0.446
7.378ProPro: 7.378 ± 1.38
2.699ProGln: 2.699 ± 0.538
5.309ProArg: 5.309 ± 0.825
5.848ProSer: 5.848 ± 0.951
3.959ProThr: 3.959 ± 0.706
4.139ProVal: 4.139 ± 0.629
0.54ProTrp: 0.54 ± 0.225
1.62ProTyr: 1.62 ± 0.439
0.0ProXaa: 0.0 ± 0.0
Gln
3.869GlnAla: 3.869 ± 0.619
0.99GlnCys: 0.99 ± 0.232
2.609GlnAsp: 2.609 ± 0.357
3.689GlnGlu: 3.689 ± 0.527
1.26GlnPhe: 1.26 ± 0.322
1.71GlnGly: 1.71 ± 0.322
1.35GlnHis: 1.35 ± 0.264
1.44GlnIle: 1.44 ± 0.305
1.71GlnLys: 1.71 ± 0.482
3.419GlnLeu: 3.419 ± 0.504
0.81GlnMet: 0.81 ± 0.247
1.89GlnAsn: 1.89 ± 0.544
3.689GlnPro: 3.689 ± 0.449
2.879GlnGln: 2.879 ± 0.745
2.789GlnArg: 2.789 ± 0.501
3.149GlnSer: 3.149 ± 0.513
2.699GlnThr: 2.699 ± 0.452
2.069GlnVal: 2.069 ± 0.415
0.27GlnTrp: 0.27 ± 0.169
0.54GlnTyr: 0.54 ± 0.238
0.0GlnXaa: 0.0 ± 0.0
Arg
7.288ArgAla: 7.288 ± 1.106
1.53ArgCys: 1.53 ± 0.292
4.049ArgAsp: 4.049 ± 0.738
3.869ArgGlu: 3.869 ± 0.756
2.339ArgPhe: 2.339 ± 0.426
5.669ArgGly: 5.669 ± 0.636
2.159ArgHis: 2.159 ± 0.505
2.429ArgIle: 2.429 ± 0.315
2.519ArgLys: 2.519 ± 0.446
5.489ArgLeu: 5.489 ± 0.77
1.44ArgMet: 1.44 ± 0.261
3.599ArgAsn: 3.599 ± 0.562
4.859ArgPro: 4.859 ± 0.763
3.149ArgGln: 3.149 ± 0.725
9.538ArgArg: 9.538 ± 1.963
4.139ArgSer: 4.139 ± 0.681
3.239ArgThr: 3.239 ± 0.676
4.679ArgVal: 4.679 ± 0.767
1.35ArgTrp: 1.35 ± 0.215
1.8ArgTyr: 1.8 ± 0.353
0.0ArgXaa: 0.0 ± 0.0
Ser
3.059SerAla: 3.059 ± 0.561
0.9SerCys: 0.9 ± 0.299
3.239SerAsp: 3.239 ± 0.446
3.419SerGlu: 3.419 ± 0.483
2.609SerPhe: 2.609 ± 0.503
5.129SerGly: 5.129 ± 0.822
2.069SerHis: 2.069 ± 0.626
2.249SerIle: 2.249 ± 0.555
1.979SerLys: 1.979 ± 0.466
6.658SerLeu: 6.658 ± 0.685
1.71SerMet: 1.71 ± 0.47
1.62SerAsn: 1.62 ± 0.346
4.049SerPro: 4.049 ± 0.797
3.149SerGln: 3.149 ± 0.581
4.139SerArg: 4.139 ± 0.639
6.748SerSer: 6.748 ± 1.156
4.589SerThr: 4.589 ± 0.729
4.769SerVal: 4.769 ± 0.621
0.81SerTrp: 0.81 ± 0.296
2.519SerTyr: 2.519 ± 0.445
0.0SerXaa: 0.0 ± 0.0
Thr
3.329ThrAla: 3.329 ± 0.562
1.35ThrCys: 1.35 ± 0.369
2.429ThrAsp: 2.429 ± 0.385
3.149ThrGlu: 3.149 ± 0.546
2.699ThrPhe: 2.699 ± 0.413
3.149ThrGly: 3.149 ± 0.587
1.44ThrHis: 1.44 ± 0.344
1.979ThrIle: 1.979 ± 0.365
1.71ThrLys: 1.71 ± 0.489
7.468ThrLeu: 7.468 ± 0.919
1.44ThrMet: 1.44 ± 0.303
2.339ThrAsn: 2.339 ± 0.72
4.859ThrPro: 4.859 ± 0.666
1.979ThrGln: 1.979 ± 0.314
3.419ThrArg: 3.419 ± 0.52
2.699ThrSer: 2.699 ± 0.386
3.239ThrThr: 3.239 ± 0.573
4.769ThrVal: 4.769 ± 0.688
0.99ThrTrp: 0.99 ± 0.329
2.789ThrTyr: 2.789 ± 0.479
0.0ThrXaa: 0.0 ± 0.0
Val
3.959ValAla: 3.959 ± 0.529
0.99ValCys: 0.99 ± 0.358
4.139ValAsp: 4.139 ± 0.592
4.409ValGlu: 4.409 ± 0.732
2.339ValPhe: 2.339 ± 0.405
3.419ValGly: 3.419 ± 0.605
0.9ValHis: 0.9 ± 0.268
2.519ValIle: 2.519 ± 0.571
2.159ValLys: 2.159 ± 0.549
6.028ValLeu: 6.028 ± 0.748
1.8ValMet: 1.8 ± 0.331
3.059ValAsn: 3.059 ± 0.51
4.049ValPro: 4.049 ± 0.533
3.059ValGln: 3.059 ± 0.625
5.219ValArg: 5.219 ± 0.615
4.409ValSer: 4.409 ± 0.588
4.409ValThr: 4.409 ± 0.709
4.949ValVal: 4.949 ± 0.705
0.81ValTrp: 0.81 ± 0.247
2.609ValTyr: 2.609 ± 0.522
0.0ValXaa: 0.0 ± 0.0
Trp
0.63TrpAla: 0.63 ± 0.222
0.18TrpCys: 0.18 ± 0.126
0.9TrpAsp: 0.9 ± 0.275
1.26TrpGlu: 1.26 ± 0.295
0.54TrpPhe: 0.54 ± 0.232
0.99TrpGly: 0.99 ± 0.266
0.0TrpHis: 0.0 ± 0.0
0.45TrpIle: 0.45 ± 0.183
0.63TrpLys: 0.63 ± 0.26
1.17TrpLeu: 1.17 ± 0.334
0.63TrpMet: 0.63 ± 0.315
0.9TrpAsn: 0.9 ± 0.349
0.54TrpPro: 0.54 ± 0.213
0.81TrpGln: 0.81 ± 0.277
0.54TrpArg: 0.54 ± 0.24
1.17TrpSer: 1.17 ± 0.291
0.81TrpThr: 0.81 ± 0.276
0.36TrpVal: 0.36 ± 0.245
0.09TrpTrp: 0.09 ± 0.082
0.63TrpTyr: 0.63 ± 0.312
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.979TyrAla: 1.979 ± 0.431
0.63TyrCys: 0.63 ± 0.28
2.069TyrAsp: 2.069 ± 0.44
2.519TyrGlu: 2.519 ± 0.466
1.62TyrPhe: 1.62 ± 0.462
2.159TyrGly: 2.159 ± 0.346
1.08TyrHis: 1.08 ± 0.314
1.26TyrIle: 1.26 ± 0.301
1.8TyrLys: 1.8 ± 0.547
3.689TyrLeu: 3.689 ± 0.65
1.26TyrMet: 1.26 ± 0.3
1.44TyrAsn: 1.44 ± 0.41
1.8TyrPro: 1.8 ± 0.426
1.53TyrGln: 1.53 ± 0.352
2.159TyrArg: 2.159 ± 0.382
1.62TyrSer: 1.62 ± 0.43
1.89TyrThr: 1.89 ± 0.357
1.44TyrVal: 1.44 ± 0.314
0.45TyrTrp: 0.45 ± 0.196
0.54TyrTyr: 0.54 ± 0.209
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 36 proteins (11115 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski