Amino acid dipepetide frequency for Aliishimia ponticola

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.143AlaAla: 16.143 ± 0.161	1.126AlaCys: 1.126 ± 0.037	7.21AlaAsp: 7.21 ± 0.08	7.975AlaGlu: 7.975 ± 0.094	4.241AlaPhe: 4.241 ± 0.061	10.465AlaGly: 10.465 ± 0.111	2.419AlaHis: 2.419 ± 0.045	5.683AlaIle: 5.683 ± 0.076	3.779AlaLys: 3.779 ± 0.066	13.501AlaLeu: 13.501 ± 0.15	3.782AlaMet: 3.782 ± 0.066	2.607AlaAsn: 2.607 ± 0.045	6.094AlaPro: 6.094 ± 0.09	5.123AlaGln: 5.123 ± 0.073	8.365AlaArg: 8.365 ± 0.101	5.574AlaSer: 5.574 ± 0.071	5.885AlaThr: 5.885 ± 0.087	8.14AlaVal: 8.14 ± 0.088	1.436AlaTrp: 1.436 ± 0.034	2.566AlaTyr: 2.566 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	1.155CysAla: 1.155 ± 0.034	0.129CysCys: 0.129 ± 0.011	0.644CysAsp: 0.644 ± 0.022	0.453CysGlu: 0.453 ± 0.02	0.338CysPhe: 0.338 ± 0.017	0.919CysGly: 0.919 ± 0.027	0.276CysHis: 0.276 ± 0.016	0.431CysIle: 0.431 ± 0.018	0.24CysLys: 0.24 ± 0.015	0.855CysLeu: 0.855 ± 0.028	0.193CysMet: 0.193 ± 0.014	0.228CysAsn: 0.228 ± 0.014	0.518CysPro: 0.518 ± 0.021	0.24CysGln: 0.24 ± 0.014	0.522CysArg: 0.522 ± 0.02	0.452CysSer: 0.452 ± 0.02	0.476CysThr: 0.476 ± 0.022	0.637CysVal: 0.637 ± 0.023	0.108CysTrp: 0.108 ± 0.01	0.241CysTyr: 0.241 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	7.88AspAla: 7.88 ± 0.084	0.518AspCys: 0.518 ± 0.019	3.85AspAsp: 3.85 ± 0.101	3.518AspGlu: 3.518 ± 0.059	2.432AspPhe: 2.432 ± 0.047	5.973AspGly: 5.973 ± 0.088	1.418AspHis: 1.418 ± 0.039	3.416AspIle: 3.416 ± 0.047	1.771AspLys: 1.771 ± 0.047	6.601AspLeu: 6.601 ± 0.08	1.856AspMet: 1.856 ± 0.041	1.41AspAsn: 1.41 ± 0.037	3.748AspPro: 3.748 ± 0.073	1.977AspGln: 1.977 ± 0.047	4.099AspArg: 4.099 ± 0.063	2.401AspSer: 2.401 ± 0.052	3.574AspThr: 3.574 ± 0.084	4.749AspVal: 4.749 ± 0.062	1.151AspTrp: 1.151 ± 0.029	1.622AspTyr: 1.622 ± 0.043	0.0AspXaa: 0.0 ± 0.0
Glu	7.892GluAla: 7.892 ± 0.111	0.364GluCys: 0.364 ± 0.016	3.699GluAsp: 3.699 ± 0.058	3.504GluGlu: 3.504 ± 0.072	1.874GluPhe: 1.874 ± 0.041	4.601GluGly: 4.601 ± 0.067	1.086GluHis: 1.086 ± 0.033	3.684GluIle: 3.684 ± 0.054	2.126GluLys: 2.126 ± 0.039	5.121GluLeu: 5.121 ± 0.076	1.843GluMet: 1.843 ± 0.037	1.846GluAsn: 1.846 ± 0.041	2.449GluPro: 2.449 ± 0.043	1.976GluGln: 1.976 ± 0.048	3.899GluArg: 3.899 ± 0.057	2.114GluSer: 2.114 ± 0.044	3.725GluThr: 3.725 ± 0.058	4.207GluVal: 4.207 ± 0.072	0.729GluTrp: 0.729 ± 0.026	1.16GluTyr: 1.16 ± 0.036	0.0GluXaa: 0.0 ± 0.0
Phe	4.528PheAla: 4.528 ± 0.065	0.468PheCys: 0.468 ± 0.02	3.125PheAsp: 3.125 ± 0.06	2.254PheGlu: 2.254 ± 0.043	1.466PhePhe: 1.466 ± 0.044	3.797PheGly: 3.797 ± 0.052	0.718PheHis: 0.718 ± 0.025	1.655PheIle: 1.655 ± 0.04	0.968PheLys: 0.968 ± 0.027	3.401PheLeu: 3.401 ± 0.056	0.872PheMet: 0.872 ± 0.026	1.098PheAsn: 1.098 ± 0.029	1.535PhePro: 1.535 ± 0.038	1.08PheGln: 1.08 ± 0.033	2.087PheArg: 2.087 ± 0.044	2.205PheSer: 2.205 ± 0.044	2.148PheThr: 2.148 ± 0.049	2.694PheVal: 2.694 ± 0.044	0.576PheTrp: 0.576 ± 0.023	0.937PheTyr: 0.937 ± 0.025	0.0PheXaa: 0.0 ± 0.0
Gly	10.245GlyAla: 10.245 ± 0.104	0.874GlyCys: 0.874 ± 0.027	5.131GlyAsp: 5.131 ± 0.119	4.459GlyGlu: 4.459 ± 0.065	3.781GlyPhe: 3.781 ± 0.061	7.615GlyGly: 7.615 ± 0.147	1.984GlyHis: 1.984 ± 0.048	4.468GlyIle: 4.468 ± 0.061	3.142GlyLys: 3.142 ± 0.066	9.086GlyLeu: 9.086 ± 0.087	2.605GlyMet: 2.605 ± 0.051	2.335GlyAsn: 2.335 ± 0.077	3.735GlyPro: 3.735 ± 0.062	3.265GlyGln: 3.265 ± 0.058	5.467GlyArg: 5.467 ± 0.068	4.171GlySer: 4.171 ± 0.069	5.014GlyThr: 5.014 ± 0.078	6.349GlyVal: 6.349 ± 0.071	1.483GlyTrp: 1.483 ± 0.039	2.363GlyTyr: 2.363 ± 0.048	0.0GlyXaa: 0.0 ± 0.0
His	2.265HisAla: 2.265 ± 0.054	0.236HisCys: 0.236 ± 0.013	1.362HisAsp: 1.362 ± 0.042	1.073HisGlu: 1.073 ± 0.034	0.795HisPhe: 0.795 ± 0.029	1.969HisGly: 1.969 ± 0.041	0.519HisHis: 0.519 ± 0.022	1.024HisIle: 1.024 ± 0.029	0.54HisLys: 0.54 ± 0.022	2.071HisLeu: 2.071 ± 0.047	0.538HisMet: 0.538 ± 0.021	0.473HisAsn: 0.473 ± 0.018	1.376HisPro: 1.376 ± 0.035	0.604HisGln: 0.604 ± 0.024	1.303HisArg: 1.303 ± 0.04	0.973HisSer: 0.973 ± 0.03	0.887HisThr: 0.887 ± 0.027	1.609HisVal: 1.609 ± 0.037	0.345HisTrp: 0.345 ± 0.018	0.542HisTyr: 0.542 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	6.984IleAla: 6.984 ± 0.072	0.642IleCys: 0.642 ± 0.024	3.763IleAsp: 3.763 ± 0.065	3.566IleGlu: 3.566 ± 0.06	1.804IlePhe: 1.804 ± 0.044	4.895IleGly: 4.895 ± 0.075	0.932IleHis: 0.932 ± 0.031	2.231IleIle: 2.231 ± 0.05	1.42IleLys: 1.42 ± 0.037	4.729IleLeu: 4.729 ± 0.072	1.086IleMet: 1.086 ± 0.03	1.362IleAsn: 1.362 ± 0.031	2.301IlePro: 2.301 ± 0.045	1.218IleGln: 1.218 ± 0.036	3.011IleArg: 3.011 ± 0.047	2.97IleSer: 2.97 ± 0.055	3.072IleThr: 3.072 ± 0.069	3.84IleVal: 3.84 ± 0.053	0.782IleTrp: 0.782 ± 0.03	1.163IleTyr: 1.163 ± 0.032	0.0IleXaa: 0.0 ± 0.0
Lys	3.826LysAla: 3.826 ± 0.066	0.191LysCys: 0.191 ± 0.013	1.853LysAsp: 1.853 ± 0.04	1.554LysGlu: 1.554 ± 0.037	0.962LysPhe: 0.962 ± 0.032	2.61LysGly: 2.61 ± 0.05	0.601LysHis: 0.601 ± 0.025	1.635LysIle: 1.635 ± 0.042	1.124LysLys: 1.124 ± 0.032	3.088LysLeu: 3.088 ± 0.047	0.915LysMet: 0.915 ± 0.027	0.771LysAsn: 0.771 ± 0.028	1.83LysPro: 1.83 ± 0.041	0.917LysGln: 0.917 ± 0.03	2.16LysArg: 2.16 ± 0.049	1.844LysSer: 1.844 ± 0.048	2.018LysThr: 2.018 ± 0.044	2.306LysVal: 2.306 ± 0.054	0.377LysTrp: 0.377 ± 0.018	0.65LysTyr: 0.65 ± 0.029	0.0LysXaa: 0.0 ± 0.0
Leu	12.267LeuAla: 12.267 ± 0.131	0.973LeuCys: 0.973 ± 0.031	6.251LeuAsp: 6.251 ± 0.071	5.379LeuGlu: 5.379 ± 0.076	3.521LeuPhe: 3.521 ± 0.063	8.296LeuGly: 8.296 ± 0.092	1.947LeuHis: 1.947 ± 0.044	5.168LeuIle: 5.168 ± 0.074	3.101LeuLys: 3.101 ± 0.061	8.746LeuLeu: 8.746 ± 0.133	2.7LeuMet: 2.7 ± 0.053	2.709LeuAsn: 2.709 ± 0.052	5.54LeuPro: 5.54 ± 0.082	2.832LeuGln: 2.832 ± 0.051	6.918LeuArg: 6.918 ± 0.079	6.654LeuSer: 6.654 ± 0.084	6.117LeuThr: 6.117 ± 0.079	6.618LeuVal: 6.618 ± 0.085	1.301LeuTrp: 1.301 ± 0.04	1.912LeuTyr: 1.912 ± 0.045	0.0LeuXaa: 0.0 ± 0.0
Met	3.32MetAla: 3.32 ± 0.058	0.216MetCys: 0.216 ± 0.014	1.512MetAsp: 1.512 ± 0.034	1.41MetGlu: 1.41 ± 0.036	0.864MetPhe: 0.864 ± 0.027	2.338MetGly: 2.338 ± 0.045	0.474MetHis: 0.474 ± 0.019	1.548MetIle: 1.548 ± 0.039	1.034MetLys: 1.034 ± 0.032	2.606MetLeu: 2.606 ± 0.045	0.803MetMet: 0.803 ± 0.028	0.821MetAsn: 0.821 ± 0.025	1.528MetPro: 1.528 ± 0.034	1.067MetGln: 1.067 ± 0.031	1.975MetArg: 1.975 ± 0.038	1.804MetSer: 1.804 ± 0.041	2.204MetThr: 2.204 ± 0.038	1.877MetVal: 1.877 ± 0.038	0.271MetTrp: 0.271 ± 0.016	0.392MetTyr: 0.392 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.264AsnAla: 3.264 ± 0.05	0.29AsnCys: 0.29 ± 0.016	1.624AsnAsp: 1.624 ± 0.053	1.188AsnGlu: 1.188 ± 0.031	1.005AsnPhe: 1.005 ± 0.029	2.535AsnGly: 2.535 ± 0.06	0.488AsnHis: 0.488 ± 0.021	1.392AsnIle: 1.392 ± 0.038	0.682AsnLys: 0.682 ± 0.026	2.545AsnLeu: 2.545 ± 0.046	0.719AsnMet: 0.719 ± 0.024	0.703AsnAsn: 0.703 ± 0.028	1.792AsnPro: 1.792 ± 0.041	0.713AsnGln: 0.713 ± 0.024	1.633AsnArg: 1.633 ± 0.038	1.24AsnSer: 1.24 ± 0.031	1.44AsnThr: 1.44 ± 0.052	1.874AsnVal: 1.874 ± 0.049	0.439AsnTrp: 0.439 ± 0.018	0.66AsnTyr: 0.66 ± 0.026	0.0AsnXaa: 0.0 ± 0.0
Pro	5.606ProAla: 5.606 ± 0.087	0.333ProCys: 0.333 ± 0.014	4.084ProAsp: 4.084 ± 0.065	4.096ProGlu: 4.096 ± 0.064	1.97ProPhe: 1.97 ± 0.04	4.553ProGly: 4.553 ± 0.067	1.053ProHis: 1.053 ± 0.031	2.314ProIle: 2.314 ± 0.046	1.696ProLys: 1.696 ± 0.043	4.554ProLeu: 4.554 ± 0.067	1.301ProMet: 1.301 ± 0.035	1.353ProAsn: 1.353 ± 0.035	2.233ProPro: 2.233 ± 0.058	1.808ProGln: 1.808 ± 0.04	2.724ProArg: 2.724 ± 0.051	2.527ProSer: 2.527 ± 0.047	2.388ProThr: 2.388 ± 0.054	4.268ProVal: 4.268 ± 0.069	0.634ProTrp: 0.634 ± 0.024	1.098ProTyr: 1.098 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	4.063GlnAla: 4.063 ± 0.068	0.225GlnCys: 0.225 ± 0.015	1.99GlnAsp: 1.99 ± 0.046	1.704GlnGlu: 1.704 ± 0.041	1.171GlnPhe: 1.171 ± 0.033	2.678GlnGly: 2.678 ± 0.044	0.62GlnHis: 0.62 ± 0.024	2.165GlnIle: 2.165 ± 0.041	1.102GlnLys: 1.102 ± 0.032	2.948GlnLeu: 2.948 ± 0.054	1.175GlnMet: 1.175 ± 0.033	0.988GlnAsn: 0.988 ± 0.029	1.652GlnPro: 1.652 ± 0.038	1.181GlnGln: 1.181 ± 0.037	2.206GlnArg: 2.206 ± 0.047	1.99GlnSer: 1.99 ± 0.041	2.118GlnThr: 2.118 ± 0.046	2.379GlnVal: 2.379 ± 0.043	0.383GlnTrp: 0.383 ± 0.016	0.646GlnTyr: 0.646 ± 0.027	0.0GlnXaa: 0.0 ± 0.0
Arg	7.846ArgAla: 7.846 ± 0.101	0.501ArgCys: 0.501 ± 0.019	4.19ArgAsp: 4.19 ± 0.069	3.605ArgGlu: 3.605 ± 0.064	2.66ArgPhe: 2.66 ± 0.051	4.487ArgGly: 4.487 ± 0.068	1.482ArgHis: 1.482 ± 0.035	3.629ArgIle: 3.629 ± 0.057	2.333ArgLys: 2.333 ± 0.04	6.81ArgLeu: 6.81 ± 0.086	1.921ArgMet: 1.921 ± 0.037	1.71ArgAsn: 1.71 ± 0.044	3.04ArgPro: 3.04 ± 0.048	2.289ArgGln: 2.289 ± 0.05	4.617ArgArg: 4.617 ± 0.082	3.219ArgSer: 3.219 ± 0.056	2.892ArgThr: 2.892 ± 0.058	4.615ArgVal: 4.615 ± 0.063	0.932ArgTrp: 0.932 ± 0.029	1.492ArgTyr: 1.492 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	6.064SerAla: 6.064 ± 0.079	0.435SerCys: 0.435 ± 0.02	3.563SerAsp: 3.563 ± 0.075	2.887SerGlu: 2.887 ± 0.047	2.267SerPhe: 2.267 ± 0.042	5.66SerGly: 5.66 ± 0.086	1.085SerHis: 1.085 ± 0.03	2.503SerIle: 2.503 ± 0.052	1.557SerLys: 1.557 ± 0.035	4.883SerLeu: 4.883 ± 0.068	1.378SerMet: 1.378 ± 0.038	1.378SerAsn: 1.378 ± 0.039	2.392SerPro: 2.392 ± 0.048	1.708SerGln: 1.708 ± 0.042	3.076SerArg: 3.076 ± 0.059	2.63SerSer: 2.63 ± 0.051	2.539SerThr: 2.539 ± 0.04	3.882SerVal: 3.882 ± 0.059	0.634SerTrp: 0.634 ± 0.024	1.31SerTyr: 1.31 ± 0.032	0.0SerXaa: 0.0 ± 0.0
Thr	6.425ThrAla: 6.425 ± 0.091	0.531ThrCys: 0.531 ± 0.025	3.418ThrAsp: 3.418 ± 0.078	3.049ThrGlu: 3.049 ± 0.051	2.089ThrPhe: 2.089 ± 0.044	5.636ThrGly: 5.636 ± 0.084	1.151ThrHis: 1.151 ± 0.033	2.839ThrIle: 2.839 ± 0.059	1.452ThrLys: 1.452 ± 0.031	5.994ThrLeu: 5.994 ± 0.083	1.358ThrMet: 1.358 ± 0.032	1.354ThrAsn: 1.354 ± 0.042	3.436ThrPro: 3.436 ± 0.067	1.846ThrGln: 1.846 ± 0.04	3.567ThrArg: 3.567 ± 0.058	2.792ThrSer: 2.792 ± 0.049	2.863ThrThr: 2.863 ± 0.06	4.48ThrVal: 4.48 ± 0.082	0.703ThrTrp: 0.703 ± 0.025	1.317ThrTyr: 1.317 ± 0.04	0.0ThrXaa: 0.0 ± 0.0
Val	8.523ValAla: 8.523 ± 0.093	0.637ValCys: 0.637 ± 0.025	4.24ValAsp: 4.24 ± 0.063	4.319ValGlu: 4.319 ± 0.066	2.886ValPhe: 2.886 ± 0.054	5.32ValGly: 5.32 ± 0.073	1.356ValHis: 1.356 ± 0.037	4.336ValIle: 4.336 ± 0.059	2.11ValLys: 2.11 ± 0.044	7.49ValLeu: 7.49 ± 0.071	2.137ValMet: 2.137 ± 0.038	2.024ValAsn: 2.024 ± 0.043	3.612ValPro: 3.612 ± 0.057	2.22ValGln: 2.22 ± 0.042	4.149ValArg: 4.149 ± 0.068	4.303ValSer: 4.303 ± 0.065	4.917ValThr: 4.917 ± 0.107	5.39ValVal: 5.39 ± 0.083	0.958ValTrp: 0.958 ± 0.024	1.489ValTyr: 1.489 ± 0.035	0.0ValXaa: 0.0 ± 0.0
Trp	1.337TrpAla: 1.337 ± 0.031	0.128TrpCys: 0.128 ± 0.009	0.809TrpAsp: 0.809 ± 0.029	0.664TrpGlu: 0.664 ± 0.025	0.549TrpPhe: 0.549 ± 0.022	1.048TrpGly: 1.048 ± 0.029	0.357TrpHis: 0.357 ± 0.018	0.702TrpIle: 0.702 ± 0.024	0.437TrpLys: 0.437 ± 0.017	1.617TrpLeu: 1.617 ± 0.038	0.402TrpMet: 0.402 ± 0.019	0.456TrpAsn: 0.456 ± 0.019	0.687TrpPro: 0.687 ± 0.023	0.602TrpGln: 0.602 ± 0.021	1.024TrpArg: 1.024 ± 0.031	0.79TrpSer: 0.79 ± 0.023	0.804TrpThr: 0.804 ± 0.026	0.905TrpVal: 0.905 ± 0.026	0.221TrpTrp: 0.221 ± 0.013	0.28TrpTyr: 0.28 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.477TyrAla: 2.477 ± 0.041	0.236TyrCys: 0.236 ± 0.013	1.644TyrAsp: 1.644 ± 0.043	1.241TyrGlu: 1.241 ± 0.035	0.938TyrPhe: 0.938 ± 0.031	2.178TyrGly: 2.178 ± 0.052	0.54TyrHis: 0.54 ± 0.022	0.947TyrIle: 0.947 ± 0.029	0.617TyrLys: 0.617 ± 0.022	2.306TyrLeu: 2.306 ± 0.048	0.479TyrMet: 0.479 ± 0.02	0.602TyrAsn: 0.602 ± 0.023	1.093TyrPro: 1.093 ± 0.035	0.717TyrGln: 0.717 ± 0.026	1.47TyrArg: 1.47 ± 0.042	1.179TyrSer: 1.179 ± 0.029	1.22TyrThr: 1.22 ± 0.036	1.597TyrVal: 1.597 ± 0.033	0.359TyrTrp: 0.359 ± 0.016	0.582TyrTyr: 0.582 ± 0.02	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3826 proteins (1230905 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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