Amino acid dipepetide frequency for Wenling crustacean virus 9

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.639AlaAla: 3.639 ± 1.722
0.91AlaCys: 0.91 ± 0.892
4.548AlaAsp: 4.548 ± 0.526
3.335AlaGlu: 3.335 ± 0.493
3.639AlaPhe: 3.639 ± 1.28
4.245AlaGly: 4.245 ± 4.212
2.122AlaHis: 2.122 ± 0.876
4.245AlaIle: 4.245 ± 1.236
4.245AlaLys: 4.245 ± 0.137
6.367AlaLeu: 6.367 ± 2.007
2.122AlaMet: 2.122 ± 0.619
1.819AlaAsn: 1.819 ± 1.667
1.516AlaPro: 1.516 ± 0.724
2.426AlaGln: 2.426 ± 0.642
4.245AlaArg: 4.245 ± 1.491
3.032AlaSer: 3.032 ± 1.21
1.819AlaThr: 1.819 ± 0.633
4.851AlaVal: 4.851 ± 1.355
0.303AlaTrp: 0.303 ± 0.163
2.122AlaTyr: 2.122 ± 0.932
0.0AlaXaa: 0.0 ± 0.0
Cys
1.516CysAla: 1.516 ± 0.374
0.606CysCys: 0.606 ± 0.644
0.91CysAsp: 0.91 ± 0.966
0.91CysGlu: 0.91 ± 0.966
0.91CysPhe: 0.91 ± 0.49
1.516CysGly: 1.516 ± 1.158
0.303CysHis: 0.303 ± 0.322
1.213CysIle: 1.213 ± 0.294
0.303CysLys: 0.303 ± 0.322
2.729CysLeu: 2.729 ± 0.592
0.303CysMet: 0.303 ± 0.163
0.303CysAsn: 0.303 ± 0.322
0.606CysPro: 0.606 ± 0.644
0.91CysGln: 0.91 ± 0.966
0.91CysArg: 0.91 ± 0.519
0.91CysSer: 0.91 ± 0.519
3.335CysThr: 3.335 ± 2.194
2.729CysVal: 2.729 ± 0.942
0.0CysTrp: 0.0 ± 0.0
0.303CysTyr: 0.303 ± 0.163
0.0CysXaa: 0.0 ± 0.0
Asp
5.155AspAla: 5.155 ± 1.703
1.516AspCys: 1.516 ± 0.724
2.729AspAsp: 2.729 ± 1.061
2.426AspGlu: 2.426 ± 1.307
2.426AspPhe: 2.426 ± 0.844
2.426AspGly: 2.426 ± 0.901
1.213AspHis: 1.213 ± 0.654
4.548AspIle: 4.548 ± 0.991
3.942AspLys: 3.942 ± 0.282
4.245AspLeu: 4.245 ± 1.488
1.213AspMet: 1.213 ± 0.654
1.819AspAsn: 1.819 ± 1.034
3.032AspPro: 3.032 ± 0.749
1.213AspGln: 1.213 ± 0.806
3.639AspArg: 3.639 ± 1.489
3.335AspSer: 3.335 ± 0.763
3.639AspThr: 3.639 ± 1.266
5.458AspVal: 5.458 ± 0.533
0.91AspTrp: 0.91 ± 0.49
3.032AspTyr: 3.032 ± 1.222
0.0AspXaa: 0.0 ± 0.0
Glu
3.942GluAla: 3.942 ± 0.711
1.213GluCys: 1.213 ± 0.294
1.819GluAsp: 1.819 ± 0.585
1.819GluGlu: 1.819 ± 0.394
2.426GluPhe: 2.426 ± 1.52
2.729GluGly: 2.729 ± 1.061
0.91GluHis: 0.91 ± 0.892
3.639GluIle: 3.639 ± 1.17
3.032GluLys: 3.032 ± 0.866
5.761GluLeu: 5.761 ± 2.283
1.819GluMet: 1.819 ± 0.656
1.213GluAsn: 1.213 ± 0.783
2.729GluPro: 2.729 ± 0.942
0.606GluGln: 0.606 ± 0.211
1.819GluArg: 1.819 ± 0.394
2.122GluSer: 2.122 ± 0.599
2.729GluThr: 2.729 ± 1.061
3.032GluVal: 3.032 ± 0.795
1.213GluTrp: 1.213 ± 0.654
1.516GluTyr: 1.516 ± 0.694
0.0GluXaa: 0.0 ± 0.0
Phe
2.729PheAla: 2.729 ± 1.471
0.606PheCys: 0.606 ± 0.211
1.213PheAsp: 1.213 ± 0.783
2.426PheGlu: 2.426 ± 0.901
2.729PhePhe: 2.729 ± 0.57
2.729PheGly: 2.729 ± 1.141
2.426PheHis: 2.426 ± 0.5
3.032PheIle: 3.032 ± 0.663
2.729PheLys: 2.729 ± 1.141
4.548PheLeu: 4.548 ± 0.991
1.516PheMet: 1.516 ± 0.817
3.032PheAsn: 3.032 ± 1.491
1.213PhePro: 1.213 ± 0.654
1.819PheGln: 1.819 ± 0.394
2.426PheArg: 2.426 ± 0.642
2.122PheSer: 2.122 ± 0.915
3.942PheThr: 3.942 ± 0.724
3.335PheVal: 3.335 ± 3.365
0.303PheTrp: 0.303 ± 0.163
0.91PheTyr: 0.91 ± 0.197
0.0PheXaa: 0.0 ± 0.0
Gly
2.426GlyAla: 2.426 ± 2.797
1.819GlyCys: 1.819 ± 1.479
3.942GlyAsp: 3.942 ± 1.015
2.122GlyGlu: 2.122 ± 0.876
3.942GlyPhe: 3.942 ± 1.326
2.426GlyGly: 2.426 ± 1.52
2.122GlyHis: 2.122 ± 1.698
3.032GlyIle: 3.032 ± 1.055
1.819GlyLys: 1.819 ± 0.722
5.761GlyLeu: 5.761 ± 0.808
2.122GlyMet: 2.122 ± 0.599
3.032GlyAsn: 3.032 ± 0.866
2.426GlyPro: 2.426 ± 0.721
1.819GlyGln: 1.819 ± 0.637
0.606GlyArg: 0.606 ± 0.327
4.851GlySer: 4.851 ± 1.053
3.032GlyThr: 3.032 ± 0.779
4.548GlyVal: 4.548 ± 0.071
0.0GlyTrp: 0.0 ± 0.0
1.516GlyTyr: 1.516 ± 0.812
0.0GlyXaa: 0.0 ± 0.0
His
1.213HisAla: 1.213 ± 0.838
0.0HisCys: 0.0 ± 0.0
1.213HisAsp: 1.213 ± 0.654
0.606HisGlu: 0.606 ± 0.211
1.213HisPhe: 1.213 ± 0.806
1.516HisGly: 1.516 ± 0.694
0.91HisHis: 0.91 ± 0.49
1.819HisIle: 1.819 ± 0.394
3.032HisLys: 3.032 ± 1.21
1.819HisLeu: 1.819 ± 0.394
1.213HisMet: 1.213 ± 0.806
1.819HisAsn: 1.819 ± 0.633
2.426HisPro: 2.426 ± 0.56
0.91HisGln: 0.91 ± 0.197
1.213HisArg: 1.213 ± 0.422
1.819HisSer: 1.819 ± 0.633
2.122HisThr: 2.122 ± 0.599
1.213HisVal: 1.213 ± 0.422
0.303HisTrp: 0.303 ± 0.163
0.91HisTyr: 0.91 ± 0.197
0.0HisXaa: 0.0 ± 0.0
Ile
4.851IleAla: 4.851 ± 1.808
1.213IleCys: 1.213 ± 0.838
4.851IleAsp: 4.851 ± 0.212
3.942IleGlu: 3.942 ± 1.015
1.516IlePhe: 1.516 ± 0.694
3.942IleGly: 3.942 ± 1.91
1.516IleHis: 1.516 ± 0.433
3.942IleIle: 3.942 ± 1.199
3.639IleLys: 3.639 ± 0.59
5.761IleLeu: 5.761 ± 0.296
1.213IleMet: 1.213 ± 0.294
2.426IleAsn: 2.426 ± 1.243
7.277IlePro: 7.277 ± 2.02
3.335IleGln: 3.335 ± 1.016
2.122IleArg: 2.122 ± 0.618
6.367IleSer: 6.367 ± 1.38
6.064IleThr: 6.064 ± 1.336
5.155IleVal: 5.155 ± 1.32
0.91IleTrp: 0.91 ± 0.966
3.335IleTyr: 3.335 ± 1.762
0.0IleXaa: 0.0 ± 0.0
Lys
2.729LysAla: 2.729 ± 0.441
2.426LysCys: 2.426 ± 1.243
2.426LysAsp: 2.426 ± 0.589
2.426LysGlu: 2.426 ± 0.5
3.032LysPhe: 3.032 ± 0.866
3.032LysGly: 3.032 ± 2.442
1.213LysHis: 1.213 ± 0.422
4.245LysIle: 4.245 ± 1.15
2.122LysLys: 2.122 ± 0.618
5.458LysLeu: 5.458 ± 1.408
1.516LysMet: 1.516 ± 0.817
3.639LysAsn: 3.639 ± 0.59
1.819LysPro: 1.819 ± 0.585
0.91LysGln: 0.91 ± 0.197
3.032LysArg: 3.032 ± 1.389
3.942LysSer: 3.942 ± 0.932
3.639LysThr: 3.639 ± 0.247
4.548LysVal: 4.548 ± 1.077
0.91LysTrp: 0.91 ± 0.49
3.639LysTyr: 3.639 ± 0.883
0.0LysXaa: 0.0 ± 0.0
Leu
4.851LeuAla: 4.851 ± 0.212
0.606LeuCys: 0.606 ± 0.211
3.639LeuAsp: 3.639 ± 1.17
5.155LeuGlu: 5.155 ± 1.053
3.335LeuPhe: 3.335 ± 0.751
4.548LeuGly: 4.548 ± 1.597
1.516LeuHis: 1.516 ± 0.374
5.458LeuIle: 5.458 ± 0.899
6.974LeuLys: 6.974 ± 1.074
8.49LeuLeu: 8.49 ± 1.129
1.819LeuMet: 1.819 ± 0.832
4.851LeuAsn: 4.851 ± 1.14
5.761LeuPro: 5.761 ± 1.587
3.639LeuGln: 3.639 ± 0.454
4.245LeuArg: 4.245 ± 0.389
6.671LeuSer: 6.671 ± 1.442
6.671LeuThr: 6.671 ± 1.865
5.458LeuVal: 5.458 ± 1.755
0.606LeuTrp: 0.606 ± 0.327
5.761LeuTyr: 5.761 ± 1.221
0.0LeuXaa: 0.0 ± 0.0
Met
1.819MetAla: 1.819 ± 1.663
0.303MetCys: 0.303 ± 0.163
0.91MetAsp: 0.91 ± 0.49
1.819MetGlu: 1.819 ± 0.85
1.213MetPhe: 1.213 ± 0.294
0.91MetGly: 0.91 ± 0.49
1.213MetHis: 1.213 ± 0.294
0.606MetIle: 0.606 ± 0.327
2.729MetLys: 2.729 ± 0.704
2.122MetLeu: 2.122 ± 0.474
0.303MetMet: 0.303 ± 0.971
0.606MetAsn: 0.606 ± 0.327
1.213MetPro: 1.213 ± 0.294
0.91MetGln: 0.91 ± 0.49
1.516MetArg: 1.516 ± 0.817
0.91MetSer: 0.91 ± 0.833
1.819MetThr: 1.819 ± 0.585
1.516MetVal: 1.516 ± 0.812
0.606MetTrp: 0.606 ± 0.327
1.516MetTyr: 1.516 ± 0.694
0.0MetXaa: 0.0 ± 0.0
Asn
1.516AsnAla: 1.516 ± 0.433
1.516AsnCys: 1.516 ± 0.724
3.032AsnAsp: 3.032 ± 0.438
1.819AsnGlu: 1.819 ± 0.637
1.819AsnPhe: 1.819 ± 1.667
2.729AsnGly: 2.729 ± 1.061
0.91AsnHis: 0.91 ± 0.966
5.458AsnIle: 5.458 ± 1.079
3.032AsnLys: 3.032 ± 1.055
3.639AsnLeu: 3.639 ± 0.247
0.606AsnMet: 0.606 ± 0.327
1.516AsnAsn: 1.516 ± 0.694
2.426AsnPro: 2.426 ± 0.5
3.639AsnGln: 3.639 ± 1.274
2.122AsnArg: 2.122 ± 1.144
3.639AsnSer: 3.639 ± 0.883
3.032AsnThr: 3.032 ± 0.438
3.639AsnVal: 3.639 ± 1.17
0.91AsnTrp: 0.91 ± 0.197
2.426AsnTyr: 2.426 ± 1.003
0.0AsnXaa: 0.0 ± 0.0
Pro
2.426ProAla: 2.426 ± 0.5
0.91ProCys: 0.91 ± 0.197
4.245ProAsp: 4.245 ± 0.945
1.819ProGlu: 1.819 ± 0.585
2.122ProPhe: 2.122 ± 0.618
2.122ProGly: 2.122 ± 0.932
0.91ProHis: 0.91 ± 0.49
3.032ProIle: 3.032 ± 0.428
2.426ProLys: 2.426 ± 0.56
3.639ProLeu: 3.639 ± 0.59
0.91ProMet: 0.91 ± 0.49
2.729ProAsn: 2.729 ± 1.109
0.606ProPro: 0.606 ± 0.327
0.91ProGln: 0.91 ± 0.197
1.819ProArg: 1.819 ± 0.394
4.245ProSer: 4.245 ± 0.947
2.426ProThr: 2.426 ± 0.56
3.942ProVal: 3.942 ± 0.293
0.606ProTrp: 0.606 ± 0.211
2.426ProTyr: 2.426 ± 0.589
0.0ProXaa: 0.0 ± 0.0
Gln
3.335GlnAla: 3.335 ± 1.38
1.213GlnCys: 1.213 ± 0.422
2.729GlnAsp: 2.729 ± 0.57
3.639GlnGlu: 3.639 ± 1.17
1.516GlnPhe: 1.516 ± 0.859
2.729GlnGly: 2.729 ± 0.441
1.819GlnHis: 1.819 ± 0.394
2.729GlnIle: 2.729 ± 1.141
1.819GlnLys: 1.819 ± 2.67
2.729GlnLeu: 2.729 ± 0.592
0.606GlnMet: 0.606 ± 0.327
3.942GlnAsn: 3.942 ± 1.326
0.606GlnPro: 0.606 ± 0.211
2.122GlnGln: 2.122 ± 0.474
2.122GlnArg: 2.122 ± 1.144
1.819GlnSer: 1.819 ± 0.637
2.122GlnThr: 2.122 ± 0.575
3.942GlnVal: 3.942 ± 0.282
0.0GlnTrp: 0.0 ± 0.0
0.606GlnTyr: 0.606 ± 0.211
0.0GlnXaa: 0.0 ± 0.0
Arg
3.032ArgAla: 3.032 ± 1.438
1.213ArgCys: 1.213 ± 0.422
3.335ArgAsp: 3.335 ± 1.323
2.729ArgGlu: 2.729 ± 1.47
1.516ArgPhe: 1.516 ± 0.812
2.729ArgGly: 2.729 ± 1.061
2.122ArgHis: 2.122 ± 0.932
3.335ArgIle: 3.335 ± 0.493
1.516ArgLys: 1.516 ± 0.433
2.729ArgLeu: 2.729 ± 1.061
1.819ArgMet: 1.819 ± 0.637
2.122ArgAsn: 2.122 ± 1.144
1.516ArgPro: 1.516 ± 0.812
2.729ArgGln: 2.729 ± 1.109
1.516ArgArg: 1.516 ± 0.374
4.245ArgSer: 4.245 ± 1.154
4.245ArgThr: 4.245 ± 1.15
2.729ArgVal: 2.729 ± 0.722
0.303ArgTrp: 0.303 ± 0.163
1.819ArgTyr: 1.819 ± 0.637
0.0ArgXaa: 0.0 ± 0.0
Ser
3.335SerAla: 3.335 ± 0.493
1.516SerCys: 1.516 ± 0.374
5.155SerAsp: 5.155 ± 0.83
1.819SerGlu: 1.819 ± 0.98
4.548SerPhe: 4.548 ± 0.071
2.729SerGly: 2.729 ± 0.57
0.91SerHis: 0.91 ± 0.833
7.884SerIle: 7.884 ± 2.096
2.729SerLys: 2.729 ± 0.704
6.974SerLeu: 6.974 ± 1.074
1.213SerMet: 1.213 ± 0.654
3.032SerAsn: 3.032 ± 0.749
0.91SerPro: 0.91 ± 0.519
2.426SerGln: 2.426 ± 0.5
4.548SerArg: 4.548 ± 1.123
3.942SerSer: 3.942 ± 0.293
3.639SerThr: 3.639 ± 1.656
5.155SerVal: 5.155 ± 0.578
0.91SerTrp: 0.91 ± 0.519
2.122SerTyr: 2.122 ± 0.575
0.0SerXaa: 0.0 ± 0.0
Thr
5.761ThrAla: 5.761 ± 1.221
2.426ThrCys: 2.426 ± 1.676
5.155ThrAsp: 5.155 ± 1.308
2.426ThrGlu: 2.426 ± 1.52
1.819ThrPhe: 1.819 ± 0.633
4.851ThrGly: 4.851 ± 2.073
0.606ThrHis: 0.606 ± 0.327
5.155ThrIle: 5.155 ± 3.232
2.729ThrLys: 2.729 ± 1.061
5.458ThrLeu: 5.458 ± 0.899
0.91ThrMet: 0.91 ± 0.49
4.851ThrAsn: 4.851 ± 0.212
3.032ThrPro: 3.032 ± 0.795
4.548ThrGln: 4.548 ± 1.3
3.335ThrArg: 3.335 ± 0.309
3.942ThrSer: 3.942 ± 1.574
3.639ThrThr: 3.639 ± 0.947
2.426ThrVal: 2.426 ± 0.56
1.213ThrTrp: 1.213 ± 0.422
4.548ThrTyr: 4.548 ± 1.408
0.0ThrXaa: 0.0 ± 0.0
Val
3.942ValAla: 3.942 ± 2.251
0.91ValCys: 0.91 ± 0.966
3.942ValAsp: 3.942 ± 0.711
3.639ValGlu: 3.639 ± 0.247
4.245ValPhe: 4.245 ± 1.125
3.639ValGly: 3.639 ± 0.59
2.426ValHis: 2.426 ± 0.589
6.367ValIle: 6.367 ± 0.562
4.548ValLys: 4.548 ± 1.455
5.761ValLeu: 5.761 ± 1.246
0.606ValMet: 0.606 ± 0.644
4.245ValAsn: 4.245 ± 1.483
2.729ValPro: 2.729 ± 1.109
3.942ValGln: 3.942 ± 0.282
2.122ValArg: 2.122 ± 0.599
4.851ValSer: 4.851 ± 1.65
6.064ValThr: 6.064 ± 1.326
4.245ValVal: 4.245 ± 0.137
0.606ValTrp: 0.606 ± 0.211
2.122ValTyr: 2.122 ± 0.474
0.0ValXaa: 0.0 ± 0.0
Trp
0.91TrpAla: 0.91 ± 0.519
0.0TrpCys: 0.0 ± 0.0
0.303TrpAsp: 0.303 ± 0.163
0.0TrpGlu: 0.0 ± 0.0
0.606TrpPhe: 0.606 ± 0.644
0.91TrpGly: 0.91 ± 0.197
0.606TrpHis: 0.606 ± 0.327
0.0TrpIle: 0.0 ± 0.0
0.303TrpLys: 0.303 ± 0.163
1.516TrpLeu: 1.516 ± 0.817
0.606TrpMet: 0.606 ± 0.327
0.0TrpAsn: 0.0 ± 0.0
0.303TrpPro: 0.303 ± 0.322
0.606TrpGln: 0.606 ± 0.327
0.303TrpArg: 0.303 ± 0.163
0.606TrpSer: 0.606 ± 0.327
1.819TrpThr: 1.819 ± 1.039
0.91TrpVal: 0.91 ± 0.49
0.0TrpTrp: 0.0 ± 0.0
0.91TrpTyr: 0.91 ± 0.49
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.426TyrAla: 2.426 ± 0.844
0.303TyrCys: 0.303 ± 0.322
1.819TyrAsp: 1.819 ± 0.394
1.213TyrGlu: 1.213 ± 0.294
1.213TyrPhe: 1.213 ± 0.422
0.91TyrGly: 0.91 ± 0.197
1.516TyrHis: 1.516 ± 0.374
3.639TyrIle: 3.639 ± 0.789
3.032TyrLys: 3.032 ± 0.749
4.851TyrLeu: 4.851 ± 0.212
1.819TyrMet: 1.819 ± 0.85
2.426TyrAsn: 2.426 ± 1.613
2.122TyrPro: 2.122 ± 0.474
2.729TyrGln: 2.729 ± 2.732
3.639TyrArg: 3.639 ± 1.961
2.122TyrSer: 2.122 ± 0.742
3.032TyrThr: 3.032 ± 1.21
2.122TyrVal: 2.122 ± 0.474
0.606TyrTrp: 0.606 ± 0.327
0.91TyrTyr: 0.91 ± 0.49
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (3299 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski