Amino acid dipepetide frequency for Cotton leaf curl Gezira virus-[Cameroon]

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.915AlaAla: 2.915 ± 1.684
0.972AlaCys: 0.972 ± 0.873
1.944AlaAsp: 1.944 ± 1.358
0.0AlaGlu: 0.0 ± 0.0
0.972AlaPhe: 0.972 ± 0.96
0.972AlaGly: 0.972 ± 0.803
2.915AlaHis: 2.915 ± 1.339
0.972AlaIle: 0.972 ± 0.96
4.859AlaLys: 4.859 ± 1.908
5.831AlaLeu: 5.831 ± 2.842
0.0AlaMet: 0.0 ± 0.0
1.944AlaAsn: 1.944 ± 1.174
3.887AlaPro: 3.887 ± 1.793
0.972AlaGln: 0.972 ± 1.02
2.915AlaArg: 2.915 ± 1.462
4.859AlaSer: 4.859 ± 1.457
3.887AlaThr: 3.887 ± 2.711
0.972AlaVal: 0.972 ± 0.853
0.972AlaTrp: 0.972 ± 0.942
0.972AlaTyr: 0.972 ± 0.803
0.0AlaXaa: 0.0 ± 0.0
Cys
0.972CysAla: 0.972 ± 0.96
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.944CysGlu: 1.944 ± 1.18
1.944CysPhe: 1.944 ± 1.248
0.972CysGly: 0.972 ± 0.96
0.972CysHis: 0.972 ± 0.85
0.0CysIle: 0.0 ± 0.0
0.972CysLys: 0.972 ± 0.942
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.972CysAsn: 0.972 ± 1.02
0.0CysPro: 0.0 ± 0.0
0.972CysGln: 0.972 ± 0.803
1.944CysArg: 1.944 ± 1.212
0.972CysSer: 0.972 ± 0.803
2.915CysThr: 2.915 ± 1.914
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.944AspAla: 1.944 ± 1.212
0.972AspCys: 0.972 ± 0.85
0.972AspAsp: 0.972 ± 0.96
1.944AspGlu: 1.944 ± 1.273
1.944AspPhe: 1.944 ± 1.074
2.915AspGly: 2.915 ± 2.409
0.0AspHis: 0.0 ± 0.0
2.915AspIle: 2.915 ± 1.35
1.944AspLys: 1.944 ± 1.212
2.915AspLeu: 2.915 ± 1.486
0.972AspMet: 0.972 ± 1.205
3.887AspAsn: 3.887 ± 2.158
0.0AspPro: 0.0 ± 0.0
0.0AspGln: 0.0 ± 0.0
2.915AspArg: 2.915 ± 1.784
4.859AspSer: 4.859 ± 1.673
0.972AspThr: 0.972 ± 0.803
2.915AspVal: 2.915 ± 1.334
2.915AspTrp: 2.915 ± 1.253
0.972AspTyr: 0.972 ± 0.873
0.0AspXaa: 0.0 ± 0.0
Glu
3.887GluAla: 3.887 ± 1.78
0.0GluCys: 0.0 ± 0.0
1.944GluAsp: 1.944 ± 1.174
3.887GluGlu: 3.887 ± 3.175
2.915GluPhe: 2.915 ± 1.667
3.887GluGly: 3.887 ± 1.63
0.0GluHis: 0.0 ± 0.0
0.0GluIle: 0.0 ± 0.0
1.944GluLys: 1.944 ± 1.245
6.803GluLeu: 6.803 ± 2.492
0.972GluMet: 0.972 ± 0.853
4.859GluAsn: 4.859 ± 2.787
0.972GluPro: 0.972 ± 0.873
1.944GluGln: 1.944 ± 1.074
0.972GluArg: 0.972 ± 0.96
2.915GluSer: 2.915 ± 1.301
3.887GluThr: 3.887 ± 1.809
0.972GluVal: 0.972 ± 0.997
1.944GluTrp: 1.944 ± 1.212
0.972GluTyr: 0.972 ± 1.02
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.0PheCys: 0.0 ± 0.0
3.887PheAsp: 3.887 ± 1.172
0.972PheGlu: 0.972 ± 0.803
1.944PhePhe: 1.944 ± 1.745
1.944PheGly: 1.944 ± 1.128
2.915PheHis: 2.915 ± 1.818
1.944PheIle: 1.944 ± 1.245
3.887PheLys: 3.887 ± 1.606
8.746PheLeu: 8.746 ± 1.957
0.972PheMet: 0.972 ± 0.853
1.944PheAsn: 1.944 ± 1.133
0.972PhePro: 0.972 ± 0.803
2.915PheGln: 2.915 ± 1.259
3.887PheArg: 3.887 ± 2.655
1.944PheSer: 1.944 ± 1.322
2.915PheThr: 2.915 ± 1.918
0.972PheVal: 0.972 ± 0.803
0.0PheTrp: 0.0 ± 0.0
0.972PheTyr: 0.972 ± 0.873
0.0PheXaa: 0.0 ± 0.0
Gly
1.944GlyAla: 1.944 ± 1.307
1.944GlyCys: 1.944 ± 1.358
2.915GlyAsp: 2.915 ± 1.486
3.887GlyGlu: 3.887 ± 1.496
2.915GlyPhe: 2.915 ± 1.661
3.887GlyGly: 3.887 ± 2.236
0.972GlyHis: 0.972 ± 0.85
3.887GlyIle: 3.887 ± 1.238
2.915GlyLys: 2.915 ± 1.359
3.887GlyLeu: 3.887 ± 1.485
0.972GlyMet: 0.972 ± 0.873
2.915GlyAsn: 2.915 ± 1.45
3.887GlyPro: 3.887 ± 1.397
3.887GlyGln: 3.887 ± 1.817
0.972GlyArg: 0.972 ± 0.803
1.944GlySer: 1.944 ± 1.174
2.915GlyThr: 2.915 ± 1.253
3.887GlyVal: 3.887 ± 1.735
0.0GlyTrp: 0.0 ± 0.0
0.972GlyTyr: 0.972 ± 0.85
0.0GlyXaa: 0.0 ± 0.0
His
0.972HisAla: 0.972 ± 0.873
0.972HisCys: 0.972 ± 0.96
0.972HisAsp: 0.972 ± 0.85
1.944HisGlu: 1.944 ± 1.212
0.972HisPhe: 0.972 ± 0.803
1.944HisGly: 1.944 ± 1.144
1.944HisHis: 1.944 ± 1.057
4.859HisIle: 4.859 ± 3.217
0.972HisLys: 0.972 ± 0.853
2.915HisLeu: 2.915 ± 1.359
0.0HisMet: 0.0 ± 0.0
3.887HisAsn: 3.887 ± 1.688
3.887HisPro: 3.887 ± 2.458
2.915HisGln: 2.915 ± 1.202
3.887HisArg: 3.887 ± 1.854
0.972HisSer: 0.972 ± 0.997
1.944HisThr: 1.944 ± 1.745
1.944HisVal: 1.944 ± 0.992
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
0.972IleCys: 0.972 ± 0.803
3.887IleAsp: 3.887 ± 1.945
0.972IleGlu: 0.972 ± 0.853
0.972IlePhe: 0.972 ± 1.02
1.944IleGly: 1.944 ± 1.386
4.859IleHis: 4.859 ± 2.926
6.803IleIle: 6.803 ± 3.424
7.775IleLys: 7.775 ± 1.501
5.831IleLeu: 5.831 ± 5.1
1.944IleMet: 1.944 ± 1.115
3.887IleAsn: 3.887 ± 1.135
2.915IlePro: 2.915 ± 1.253
4.859IleGln: 4.859 ± 1.071
7.775IleArg: 7.775 ± 1.781
7.775IleSer: 7.775 ± 2.245
3.887IleThr: 3.887 ± 1.921
1.944IleVal: 1.944 ± 1.128
0.972IleTrp: 0.972 ± 0.853
0.972IleTyr: 0.972 ± 0.873
0.0IleXaa: 0.0 ± 0.0
Lys
0.0LysAla: 0.0 ± 0.0
2.915LysCys: 2.915 ± 1.59
2.915LysAsp: 2.915 ± 1.914
5.831LysGlu: 5.831 ± 1.701
1.944LysPhe: 1.944 ± 1.074
2.915LysGly: 2.915 ± 1.512
1.944LysHis: 1.944 ± 1.7
6.803LysIle: 6.803 ± 1.872
3.887LysLys: 3.887 ± 1.097
1.944LysLeu: 1.944 ± 1.144
0.972LysMet: 0.972 ± 0.725
5.831LysAsn: 5.831 ± 2.423
3.887LysPro: 3.887 ± 1.912
1.944LysGln: 1.944 ± 1.133
4.859LysArg: 4.859 ± 2.705
3.887LysSer: 3.887 ± 1.853
1.944LysThr: 1.944 ± 0.992
2.915LysVal: 2.915 ± 2.131
0.0LysTrp: 0.0 ± 0.0
3.887LysTyr: 3.887 ± 1.384
0.0LysXaa: 0.0 ± 0.0
Leu
0.972LeuAla: 0.972 ± 0.803
0.972LeuCys: 0.972 ± 1.02
2.915LeuAsp: 2.915 ± 1.993
3.887LeuGlu: 3.887 ± 1.577
3.887LeuPhe: 3.887 ± 1.689
3.887LeuGly: 3.887 ± 2.288
4.859LeuHis: 4.859 ± 2.621
6.803LeuIle: 6.803 ± 2.464
4.859LeuLys: 4.859 ± 1.974
5.831LeuLeu: 5.831 ± 2.027
1.944LeuMet: 1.944 ± 1.633
4.859LeuAsn: 4.859 ± 1.254
0.972LeuPro: 0.972 ± 0.96
5.831LeuGln: 5.831 ± 2.383
3.887LeuArg: 3.887 ± 1.689
3.887LeuSer: 3.887 ± 1.912
9.718LeuThr: 9.718 ± 2.652
3.887LeuVal: 3.887 ± 1.773
0.0LeuTrp: 0.0 ± 0.0
8.746LeuTyr: 8.746 ± 3.38
0.0LeuXaa: 0.0 ± 0.0
Met
2.915MetAla: 2.915 ± 1.371
0.972MetCys: 0.972 ± 0.997
2.915MetAsp: 2.915 ± 1.834
0.972MetGlu: 0.972 ± 0.997
2.915MetPhe: 2.915 ± 1.784
1.944MetGly: 1.944 ± 1.245
0.0MetHis: 0.0 ± 0.0
0.972MetIle: 0.972 ± 0.853
1.944MetLys: 1.944 ± 1.133
0.972MetLeu: 0.972 ± 0.85
1.944MetMet: 1.944 ± 1.806
1.944MetAsn: 1.944 ± 1.334
0.0MetPro: 0.0 ± 0.0
0.972MetGln: 0.972 ± 0.853
1.944MetArg: 1.944 ± 1.136
1.944MetSer: 1.944 ± 1.18
0.972MetThr: 0.972 ± 0.997
1.944MetVal: 1.944 ± 1.7
0.0MetTrp: 0.0 ± 0.0
1.944MetTyr: 1.944 ± 1.885
0.0MetXaa: 0.0 ± 0.0
Asn
6.803AsnAla: 6.803 ± 2.556
0.0AsnCys: 0.0 ± 0.0
2.915AsnAsp: 2.915 ± 1.259
0.972AsnGlu: 0.972 ± 0.873
2.915AsnPhe: 2.915 ± 1.334
2.915AsnGly: 2.915 ± 1.156
5.831AsnHis: 5.831 ± 2.397
3.887AsnIle: 3.887 ± 1.135
3.887AsnLys: 3.887 ± 1.731
4.859AsnLeu: 4.859 ± 2.445
2.915AsnMet: 2.915 ± 1.912
3.887AsnAsn: 3.887 ± 1.135
4.859AsnPro: 4.859 ± 1.997
3.887AsnGln: 3.887 ± 2.229
2.915AsnArg: 2.915 ± 1.34
4.859AsnSer: 4.859 ± 2.067
2.915AsnThr: 2.915 ± 1.871
3.887AsnVal: 3.887 ± 1.868
0.0AsnTrp: 0.0 ± 0.0
2.915AsnTyr: 2.915 ± 1.334
0.0AsnXaa: 0.0 ± 0.0
Pro
2.915ProAla: 2.915 ± 1.999
1.944ProCys: 1.944 ± 1.358
0.972ProAsp: 0.972 ± 0.942
0.0ProGlu: 0.0 ± 0.0
0.972ProPhe: 0.972 ± 0.85
2.915ProGly: 2.915 ± 1.487
0.972ProHis: 0.972 ± 0.803
1.944ProIle: 1.944 ± 1.057
2.915ProLys: 2.915 ± 1.72
1.944ProLeu: 1.944 ± 1.231
1.944ProMet: 1.944 ± 1.322
3.887ProAsn: 3.887 ± 1.935
0.972ProPro: 0.972 ± 0.853
3.887ProGln: 3.887 ± 2.771
1.944ProArg: 1.944 ± 1.18
7.775ProSer: 7.775 ± 2.643
5.831ProThr: 5.831 ± 2.068
2.915ProVal: 2.915 ± 1.332
0.0ProTrp: 0.0 ± 0.0
1.944ProTyr: 1.944 ± 1.128
0.0ProXaa: 0.0 ± 0.0
Gln
1.944GlnAla: 1.944 ± 1.322
0.0GlnCys: 0.0 ± 0.0
0.972GlnAsp: 0.972 ± 1.02
4.859GlnGlu: 4.859 ± 2.345
1.944GlnPhe: 1.944 ± 1.606
1.944GlnGly: 1.944 ± 1.212
1.944GlnHis: 1.944 ± 1.386
7.775GlnIle: 7.775 ± 2.259
1.944GlnLys: 1.944 ± 1.307
1.944GlnLeu: 1.944 ± 1.212
0.972GlnMet: 0.972 ± 0.96
2.915GlnAsn: 2.915 ± 1.259
2.915GlnPro: 2.915 ± 1.486
2.915GlnGln: 2.915 ± 1.673
1.944GlnArg: 1.944 ± 1.995
5.831GlnSer: 5.831 ± 2.021
3.887GlnThr: 3.887 ± 1.784
2.915GlnVal: 2.915 ± 1.784
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.887ArgAla: 3.887 ± 2.287
0.972ArgCys: 0.972 ± 0.96
3.887ArgAsp: 3.887 ± 2.272
5.831ArgGlu: 5.831 ± 3.282
3.887ArgPhe: 3.887 ± 1.764
2.915ArgGly: 2.915 ± 1.139
0.0ArgHis: 0.0 ± 0.0
2.915ArgIle: 2.915 ± 1.914
3.887ArgLys: 3.887 ± 2.034
5.831ArgLeu: 5.831 ± 2.469
2.915ArgMet: 2.915 ± 2.027
0.972ArgAsn: 0.972 ± 0.85
4.859ArgPro: 4.859 ± 2.172
1.944ArgGln: 1.944 ± 1.995
8.746ArgArg: 8.746 ± 3.651
5.831ArgSer: 5.831 ± 1.759
2.915ArgThr: 2.915 ± 1.156
1.944ArgVal: 1.944 ± 0.992
0.0ArgTrp: 0.0 ± 0.0
0.972ArgTyr: 0.972 ± 0.85
0.0ArgXaa: 0.0 ± 0.0
Ser
3.887SerAla: 3.887 ± 1.696
0.0SerCys: 0.0 ± 0.0
1.944SerAsp: 1.944 ± 1.212
2.915SerGlu: 2.915 ± 1.76
1.944SerPhe: 1.944 ± 1.057
4.859SerGly: 4.859 ± 2.199
0.972SerHis: 0.972 ± 0.85
4.859SerIle: 4.859 ± 2.445
4.859SerLys: 4.859 ± 2.27
2.915SerLeu: 2.915 ± 1.673
2.915SerMet: 2.915 ± 1.668
9.718SerAsn: 9.718 ± 3.236
7.775SerPro: 7.775 ± 2.465
2.915SerGln: 2.915 ± 1.914
2.915SerArg: 2.915 ± 1.891
17.493SerSer: 17.493 ± 5.467
9.718SerThr: 9.718 ± 3.27
1.944SerVal: 1.944 ± 1.145
0.972SerTrp: 0.972 ± 1.02
3.887SerTyr: 3.887 ± 1.402
0.0SerXaa: 0.0 ± 0.0
Thr
3.887ThrAla: 3.887 ± 1.606
1.944ThrCys: 1.944 ± 1.057
0.0ThrAsp: 0.0 ± 0.0
2.915ThrGlu: 2.915 ± 1.371
2.915ThrPhe: 2.915 ± 1.523
3.887ThrGly: 3.887 ± 1.868
6.803ThrHis: 6.803 ± 1.995
4.859ThrIle: 4.859 ± 2.629
4.859ThrLys: 4.859 ± 2.542
6.803ThrLeu: 6.803 ± 2.259
1.944ThrMet: 1.944 ± 1.144
5.831ThrAsn: 5.831 ± 2.539
2.915ThrPro: 2.915 ± 1.62
2.915ThrGln: 2.915 ± 1.569
0.972ThrArg: 0.972 ± 0.997
3.887ThrSer: 3.887 ± 2.159
2.915ThrThr: 2.915 ± 1.826
5.831ThrVal: 5.831 ± 1.719
1.944ThrTrp: 1.944 ± 1.08
0.972ThrTyr: 0.972 ± 0.96
0.0ThrXaa: 0.0 ± 0.0
Val
0.972ValAla: 0.972 ± 0.96
0.0ValCys: 0.0 ± 0.0
0.0ValAsp: 0.0 ± 0.0
0.972ValGlu: 0.972 ± 0.853
2.915ValPhe: 2.915 ± 1.202
0.972ValGly: 0.972 ± 0.85
0.0ValHis: 0.0 ± 0.0
4.859ValIle: 4.859 ± 2.089
1.944ValLys: 1.944 ± 1.074
7.775ValLeu: 7.775 ± 2.792
2.915ValMet: 2.915 ± 1.805
1.944ValAsn: 1.944 ± 1.144
1.944ValPro: 1.944 ± 1.358
2.915ValGln: 2.915 ± 1.487
3.887ValArg: 3.887 ± 2.004
2.915ValSer: 2.915 ± 1.259
1.944ValThr: 1.944 ± 1.145
0.0ValVal: 0.0 ± 0.0
0.972ValTrp: 0.972 ± 0.853
2.915ValTyr: 2.915 ± 1.784
0.0ValXaa: 0.0 ± 0.0
Trp
0.972TrpAla: 0.972 ± 1.02
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.972TrpGly: 0.972 ± 0.803
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.972TrpLeu: 0.972 ± 0.85
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.972TrpGln: 0.972 ± 1.02
0.972TrpArg: 0.972 ± 0.96
1.944TrpSer: 1.944 ± 1.358
2.915TrpThr: 2.915 ± 1.83
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.972TrpTyr: 0.972 ± 0.997
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.944TyrAla: 1.944 ± 1.074
0.0TyrCys: 0.0 ± 0.0
3.887TyrAsp: 3.887 ± 1.465
0.972TyrGlu: 0.972 ± 0.873
2.915TyrPhe: 2.915 ± 1.134
2.915TyrGly: 2.915 ± 1.577
0.0TyrHis: 0.0 ± 0.0
3.887TyrIle: 3.887 ± 1.999
0.972TyrLys: 0.972 ± 1.02
3.887TyrLeu: 3.887 ± 1.238
1.944TyrMet: 1.944 ± 1.115
1.944TyrAsn: 1.944 ± 1.133
0.972TyrPro: 0.972 ± 0.997
0.0TyrGln: 0.0 ± 0.0
4.859TyrArg: 4.859 ± 2.958
2.915TyrSer: 2.915 ± 1.871
0.0TyrThr: 0.0 ± 0.0
0.972TyrVal: 0.972 ± 0.96
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (1030 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski