Amino acid dipepetide frequency for Plantago lanceolata latent virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.184AlaAla: 4.184 ± 1.041
0.0AlaCys: 0.0 ± 0.0
3.347AlaAsp: 3.347 ± 1.284
2.51AlaGlu: 2.51 ± 0.896
3.347AlaPhe: 3.347 ± 1.618
3.347AlaGly: 3.347 ± 1.278
1.674AlaHis: 1.674 ± 0.809
4.184AlaIle: 4.184 ± 1.544
5.858AlaLys: 5.858 ± 1.545
3.347AlaLeu: 3.347 ± 1.424
2.51AlaMet: 2.51 ± 1.124
5.858AlaAsn: 5.858 ± 2.066
0.0AlaPro: 0.0 ± 0.0
3.347AlaGln: 3.347 ± 1.618
6.695AlaArg: 6.695 ± 1.481
1.674AlaSer: 1.674 ± 1.093
8.368AlaThr: 8.368 ± 2.108
0.0AlaVal: 0.0 ± 0.0
1.674AlaTrp: 1.674 ± 0.848
1.674AlaTyr: 1.674 ± 0.92
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
2.51CysAsp: 2.51 ± 0.896
0.837CysGlu: 0.837 ± 0.899
0.0CysPhe: 0.0 ± 0.0
0.837CysGly: 0.837 ± 0.641
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.837CysLys: 0.837 ± 0.641
1.674CysLeu: 1.674 ± 0.809
0.837CysMet: 0.837 ± 0.998
2.51CysAsn: 2.51 ± 1.285
0.0CysPro: 0.0 ± 0.0
1.674CysGln: 1.674 ± 0.809
1.674CysArg: 1.674 ± 1.832
0.837CysSer: 0.837 ± 0.916
0.0CysThr: 0.0 ± 0.0
0.837CysVal: 0.837 ± 0.78
0.0CysTrp: 0.0 ± 0.0
0.837CysTyr: 0.837 ± 0.916
0.0CysXaa: 0.0 ± 0.0
Asp
4.184AspAla: 4.184 ± 2.129
0.837AspCys: 0.837 ± 0.78
0.837AspAsp: 0.837 ± 0.641
0.837AspGlu: 0.837 ± 0.899
3.347AspPhe: 3.347 ± 1.152
6.695AspGly: 6.695 ± 1.525
1.674AspHis: 1.674 ± 0.848
5.021AspIle: 5.021 ± 2.427
2.51AspLys: 2.51 ± 1.499
4.184AspLeu: 4.184 ± 1.751
0.0AspMet: 0.0 ± 0.0
1.674AspAsn: 1.674 ± 1.157
2.51AspPro: 2.51 ± 1.36
1.674AspGln: 1.674 ± 0.952
1.674AspArg: 1.674 ± 0.848
1.674AspSer: 1.674 ± 1.072
3.347AspThr: 3.347 ± 0.615
1.674AspVal: 1.674 ± 1.072
1.674AspTrp: 1.674 ± 0.809
5.021AspTyr: 5.021 ± 1.166
0.0AspXaa: 0.0 ± 0.0
Glu
5.021GluAla: 5.021 ± 3.265
0.0GluCys: 0.0 ± 0.0
0.0GluAsp: 0.0 ± 0.0
4.184GluGlu: 4.184 ± 2.038
2.51GluPhe: 2.51 ± 1.334
1.674GluGly: 1.674 ± 1.036
0.837GluHis: 0.837 ± 0.689
4.184GluIle: 4.184 ± 1.865
2.51GluLys: 2.51 ± 1.067
1.674GluLeu: 1.674 ± 0.967
1.674GluMet: 1.674 ± 0.822
2.51GluAsn: 2.51 ± 0.896
5.021GluPro: 5.021 ± 2.427
3.347GluGln: 3.347 ± 1.507
4.184GluArg: 4.184 ± 0.81
4.184GluSer: 4.184 ± 0.81
3.347GluThr: 3.347 ± 1.75
2.51GluVal: 2.51 ± 1.931
0.837GluTrp: 0.837 ± 0.641
4.184GluTyr: 4.184 ± 1.709
0.0GluXaa: 0.0 ± 0.0
Phe
0.837PheAla: 0.837 ± 0.916
0.0PheCys: 0.0 ± 0.0
2.51PheAsp: 2.51 ± 0.791
1.674PheGlu: 1.674 ± 1.157
0.837PhePhe: 0.837 ± 0.998
0.0PheGly: 0.0 ± 0.0
0.0PheHis: 0.0 ± 0.0
0.0PheIle: 0.0 ± 0.0
0.837PheLys: 0.837 ± 0.78
5.021PheLeu: 5.021 ± 2.068
0.837PheMet: 0.837 ± 0.998
2.51PheAsn: 2.51 ± 1.16
1.674PhePro: 1.674 ± 0.809
3.347PheGln: 3.347 ± 1.221
2.51PheArg: 2.51 ± 2.34
0.0PheSer: 0.0 ± 0.0
3.347PheThr: 3.347 ± 1.634
2.51PheVal: 2.51 ± 0.929
0.837PheTrp: 0.837 ± 0.916
3.347PheTyr: 3.347 ± 1.221
0.0PheXaa: 0.0 ± 0.0
Gly
1.674GlyAla: 1.674 ± 0.848
0.0GlyCys: 0.0 ± 0.0
1.674GlyAsp: 1.674 ± 0.809
3.347GlyGlu: 3.347 ± 2.492
0.837GlyPhe: 0.837 ± 0.899
2.51GlyGly: 2.51 ± 1.499
0.837GlyHis: 0.837 ± 0.78
1.674GlyIle: 1.674 ± 0.92
6.695GlyLys: 6.695 ± 1.959
1.674GlyLeu: 1.674 ± 1.996
0.837GlyMet: 0.837 ± 0.845
2.51GlyAsn: 2.51 ± 0.791
2.51GlyPro: 2.51 ± 0.929
1.674GlyGln: 1.674 ± 1.996
4.184GlyArg: 4.184 ± 2.376
3.347GlySer: 3.347 ± 2.234
3.347GlyThr: 3.347 ± 1.347
3.347GlyVal: 3.347 ± 1.347
0.837GlyTrp: 0.837 ± 0.78
1.674GlyTyr: 1.674 ± 1.56
0.0GlyXaa: 0.0 ± 0.0
His
1.674HisAla: 1.674 ± 0.809
1.674HisCys: 1.674 ± 0.809
0.837HisAsp: 0.837 ± 0.78
0.837HisGlu: 0.837 ± 0.641
0.0HisPhe: 0.0 ± 0.0
0.837HisGly: 0.837 ± 0.998
1.674HisHis: 1.674 ± 0.809
0.837HisIle: 0.837 ± 0.641
0.0HisLys: 0.0 ± 0.0
2.51HisLeu: 2.51 ± 0.791
0.0HisMet: 0.0 ± 0.0
1.674HisAsn: 1.674 ± 0.848
2.51HisPro: 2.51 ± 0.929
1.674HisGln: 1.674 ± 0.809
1.674HisArg: 1.674 ± 0.848
2.51HisSer: 2.51 ± 1.588
0.837HisThr: 0.837 ± 0.998
2.51HisVal: 2.51 ± 0.791
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.184IleAla: 4.184 ± 1.544
0.0IleCys: 0.0 ± 0.0
4.184IleAsp: 4.184 ± 2.054
4.184IleGlu: 4.184 ± 1.715
2.51IlePhe: 2.51 ± 0.929
0.0IleGly: 0.0 ± 0.0
0.0IleHis: 0.0 ± 0.0
4.184IleIle: 4.184 ± 1.451
1.674IleLys: 1.674 ± 0.809
4.184IleLeu: 4.184 ± 1.327
0.0IleMet: 0.0 ± 0.0
1.674IleAsn: 1.674 ± 1.157
5.021IlePro: 5.021 ± 1.415
3.347IleGln: 3.347 ± 1.142
1.674IleArg: 1.674 ± 1.419
0.837IleSer: 0.837 ± 0.998
6.695IleThr: 6.695 ± 2.733
3.347IleVal: 3.347 ± 1.608
1.674IleTrp: 1.674 ± 0.809
1.674IleTyr: 1.674 ± 1.321
0.0IleXaa: 0.0 ± 0.0
Lys
2.51LysAla: 2.51 ± 0.791
1.674LysCys: 1.674 ± 0.809
5.021LysAsp: 5.021 ± 1.376
1.674LysGlu: 1.674 ± 0.952
0.0LysPhe: 0.0 ± 0.0
1.674LysGly: 1.674 ± 1.56
2.51LysHis: 2.51 ± 1.287
2.51LysIle: 2.51 ± 1.334
3.347LysLys: 3.347 ± 1.865
0.837LysLeu: 0.837 ± 0.899
0.0LysMet: 0.0 ± 0.0
2.51LysAsn: 2.51 ± 0.791
1.674LysPro: 1.674 ± 0.809
2.51LysGln: 2.51 ± 0.929
7.531LysArg: 7.531 ± 3.494
5.858LysSer: 5.858 ± 1.354
3.347LysThr: 3.347 ± 2.001
3.347LysVal: 3.347 ± 1.608
0.0LysTrp: 0.0 ± 0.0
4.184LysTyr: 4.184 ± 1.488
0.0LysXaa: 0.0 ± 0.0
Leu
3.347LeuAla: 3.347 ± 1.618
1.674LeuCys: 1.674 ± 0.952
2.51LeuAsp: 2.51 ± 1.36
3.347LeuGlu: 3.347 ± 1.284
0.837LeuPhe: 0.837 ± 0.916
5.021LeuGly: 5.021 ± 1.252
5.021LeuHis: 5.021 ± 1.217
5.858LeuIle: 5.858 ± 2.322
3.347LeuLys: 3.347 ± 1.618
6.695LeuLeu: 6.695 ± 2.721
0.0LeuMet: 0.0 ± 0.0
3.347LeuAsn: 3.347 ± 1.834
4.184LeuPro: 4.184 ± 1.16
5.021LeuGln: 5.021 ± 1.734
4.184LeuArg: 4.184 ± 1.85
3.347LeuSer: 3.347 ± 2.055
6.695LeuThr: 6.695 ± 3.236
5.021LeuVal: 5.021 ± 1.42
0.0LeuTrp: 0.0 ± 0.0
10.879LeuTyr: 10.879 ± 0.69
0.0LeuXaa: 0.0 ± 0.0
Met
1.674MetAla: 1.674 ± 1.246
0.0MetCys: 0.0 ± 0.0
0.837MetAsp: 0.837 ± 0.78
1.674MetGlu: 1.674 ± 1.321
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.837MetIle: 0.837 ± 0.998
0.0MetLys: 0.0 ± 0.0
0.837MetLeu: 0.837 ± 0.998
0.837MetMet: 0.837 ± 0.78
0.837MetAsn: 0.837 ± 0.998
2.51MetPro: 2.51 ± 0.929
1.674MetGln: 1.674 ± 0.864
0.0MetArg: 0.0 ± 0.0
0.0MetSer: 0.0 ± 0.0
0.0MetThr: 0.0 ± 0.0
0.837MetVal: 0.837 ± 0.78
0.0MetTrp: 0.0 ± 0.0
1.674MetTyr: 1.674 ± 1.282
0.0MetXaa: 0.0 ± 0.0
Asn
2.51AsnAla: 2.51 ± 2.34
0.837AsnCys: 0.837 ± 0.916
0.837AsnAsp: 0.837 ± 0.78
2.51AsnGlu: 2.51 ± 0.837
1.674AsnPhe: 1.674 ± 0.809
3.347AsnGly: 3.347 ± 1.62
2.51AsnHis: 2.51 ± 0.929
1.674AsnIle: 1.674 ± 0.809
0.0AsnLys: 0.0 ± 0.0
7.531AsnLeu: 7.531 ± 2.921
0.0AsnMet: 0.0 ± 0.0
0.837AsnAsn: 0.837 ± 0.998
2.51AsnPro: 2.51 ± 1.81
0.0AsnGln: 0.0 ± 0.0
0.0AsnArg: 0.0 ± 0.0
8.368AsnSer: 8.368 ± 1.724
5.858AsnThr: 5.858 ± 1.631
5.021AsnVal: 5.021 ± 2.997
0.0AsnTrp: 0.0 ± 0.0
2.51AsnTyr: 2.51 ± 1.287
0.0AsnXaa: 0.0 ± 0.0
Pro
0.0ProAla: 0.0 ± 0.0
0.837ProCys: 0.837 ± 0.641
5.858ProAsp: 5.858 ± 1.98
8.368ProGlu: 8.368 ± 3.086
1.674ProPhe: 1.674 ± 1.282
2.51ProGly: 2.51 ± 1.124
1.674ProHis: 1.674 ± 0.809
5.021ProIle: 5.021 ± 1.857
5.858ProLys: 5.858 ± 2.126
4.184ProLeu: 4.184 ± 1.457
0.0ProMet: 0.0 ± 0.0
3.347ProAsn: 3.347 ± 1.618
3.347ProPro: 3.347 ± 1.75
2.51ProGln: 2.51 ± 1.029
5.858ProArg: 5.858 ± 2.126
4.184ProSer: 4.184 ± 1.298
5.858ProThr: 5.858 ± 3.493
2.51ProVal: 2.51 ± 0.929
0.0ProTrp: 0.0 ± 0.0
1.674ProTyr: 1.674 ± 0.809
0.0ProXaa: 0.0 ± 0.0
Gln
1.674GlnAla: 1.674 ± 1.799
0.0GlnCys: 0.0 ± 0.0
3.347GlnAsp: 3.347 ± 1.103
5.021GlnGlu: 5.021 ± 1.916
1.674GlnPhe: 1.674 ± 0.848
1.674GlnGly: 1.674 ± 0.809
0.837GlnHis: 0.837 ± 0.998
0.0GlnIle: 0.0 ± 0.0
3.347GlnLys: 3.347 ± 1.781
6.695GlnLeu: 6.695 ± 2.89
0.837GlnMet: 0.837 ± 0.862
1.674GlnAsn: 1.674 ± 1.996
7.531GlnPro: 7.531 ± 2.884
1.674GlnGln: 1.674 ± 0.809
0.0GlnArg: 0.0 ± 0.0
5.858GlnSer: 5.858 ± 1.297
2.51GlnThr: 2.51 ± 2.001
2.51GlnVal: 2.51 ± 0.896
3.347GlnTrp: 3.347 ± 0.834
0.837GlnTyr: 0.837 ± 0.78
0.0GlnXaa: 0.0 ± 0.0
Arg
3.347ArgAla: 3.347 ± 1.221
0.0ArgCys: 0.0 ± 0.0
4.184ArgAsp: 4.184 ± 1.397
1.674ArgGlu: 1.674 ± 1.832
5.858ArgPhe: 5.858 ± 2.38
2.51ArgGly: 2.51 ± 0.896
2.51ArgHis: 2.51 ± 1.499
4.184ArgIle: 4.184 ± 2.402
3.347ArgLys: 3.347 ± 1.331
5.021ArgLeu: 5.021 ± 1.9
1.674ArgMet: 1.674 ± 1.072
3.347ArgAsn: 3.347 ± 1.75
2.51ArgPro: 2.51 ± 1.459
5.021ArgGln: 5.021 ± 2.385
7.531ArgArg: 7.531 ± 4.309
8.368ArgSer: 8.368 ± 1.394
0.837ArgThr: 0.837 ± 0.998
5.858ArgVal: 5.858 ± 1.18
3.347ArgTrp: 3.347 ± 0.834
2.51ArgTyr: 2.51 ± 0.929
0.0ArgXaa: 0.0 ± 0.0
Ser
4.184SerAla: 4.184 ± 1.255
1.674SerCys: 1.674 ± 1.153
4.184SerAsp: 4.184 ± 1.003
3.347SerGlu: 3.347 ± 1.024
2.51SerPhe: 2.51 ± 1.495
4.184SerGly: 4.184 ± 1.054
0.0SerHis: 0.0 ± 0.0
0.0SerIle: 0.0 ± 0.0
3.347SerLys: 3.347 ± 1.422
5.858SerLeu: 5.858 ± 2.786
0.837SerMet: 0.837 ± 0.689
3.347SerAsn: 3.347 ± 1.834
8.368SerPro: 8.368 ± 7.622
4.184SerGln: 4.184 ± 1.614
10.042SerArg: 10.042 ± 2.253
6.695SerSer: 6.695 ± 4.3
5.858SerThr: 5.858 ± 3.404
5.021SerVal: 5.021 ± 1.514
0.0SerTrp: 0.0 ± 0.0
4.184SerTyr: 4.184 ± 1.523
0.0SerXaa: 0.0 ± 0.0
Thr
6.695ThrAla: 6.695 ± 2.121
0.0ThrCys: 0.0 ± 0.0
1.674ThrAsp: 1.674 ± 0.848
3.347ThrGlu: 3.347 ± 1.741
0.837ThrPhe: 0.837 ± 0.78
3.347ThrGly: 3.347 ± 1.331
0.837ThrHis: 0.837 ± 0.998
5.858ThrIle: 5.858 ± 1.787
3.347ThrLys: 3.347 ± 1.152
2.51ThrLeu: 2.51 ± 1.191
0.0ThrMet: 0.0 ± 0.618
3.347ThrAsn: 3.347 ± 1.024
3.347ThrPro: 3.347 ± 1.75
5.021ThrGln: 5.021 ± 2.421
3.347ThrArg: 3.347 ± 1.618
12.552ThrSer: 12.552 ± 7.156
6.695ThrThr: 6.695 ± 1.23
3.347ThrVal: 3.347 ± 1.352
2.51ThrTrp: 2.51 ± 0.929
5.021ThrTyr: 5.021 ± 1.442
0.0ThrXaa: 0.0 ± 0.0
Val
4.184ValAla: 4.184 ± 0.81
2.51ValCys: 2.51 ± 1.287
2.51ValAsp: 2.51 ± 1.067
1.674ValGlu: 1.674 ± 0.809
0.0ValPhe: 0.0 ± 0.0
2.51ValGly: 2.51 ± 1.402
0.837ValHis: 0.837 ± 0.78
1.674ValIle: 1.674 ± 0.848
5.021ValLys: 5.021 ± 3.514
9.205ValLeu: 9.205 ± 2.801
1.674ValMet: 1.674 ± 1.067
2.51ValAsn: 2.51 ± 1.124
4.184ValPro: 4.184 ± 1.255
3.347ValGln: 3.347 ± 1.618
4.184ValArg: 4.184 ± 2.427
2.51ValSer: 2.51 ± 1.562
0.837ValThr: 0.837 ± 0.78
1.674ValVal: 1.674 ± 1.072
0.0ValTrp: 0.0 ± 0.0
1.674ValTyr: 1.674 ± 1.56
0.0ValXaa: 0.0 ± 0.0
Trp
5.021TrpAla: 5.021 ± 2.427
0.837TrpCys: 0.837 ± 0.899
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.837TrpHis: 0.837 ± 0.78
0.0TrpIle: 0.0 ± 0.0
0.837TrpLys: 0.837 ± 0.78
0.837TrpLeu: 0.837 ± 0.899
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
1.674TrpPro: 1.674 ± 0.809
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
4.184TrpSer: 4.184 ± 1.177
2.51TrpThr: 2.51 ± 1.094
0.837TrpVal: 0.837 ± 0.78
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
6.695TyrAla: 6.695 ± 1.525
3.347TyrCys: 3.347 ± 1.915
4.184TyrAsp: 4.184 ± 1.041
3.347TyrGlu: 3.347 ± 1.221
4.184TyrPhe: 4.184 ± 2.705
2.51TyrGly: 2.51 ± 1.757
0.0TyrHis: 0.0 ± 0.0
3.347TyrIle: 3.347 ± 1.347
0.0TyrLys: 0.0 ± 0.0
5.858TyrLeu: 5.858 ± 1.676
0.837TyrMet: 0.837 ± 0.586
2.51TyrAsn: 2.51 ± 1.287
4.184TyrPro: 4.184 ± 1.054
0.0TyrGln: 0.0 ± 0.0
6.695TyrArg: 6.695 ± 2.034
0.837TyrSer: 0.837 ± 0.998
4.184TyrThr: 4.184 ± 1.397
0.0TyrVal: 0.0 ± 0.0
0.837TyrTrp: 0.837 ± 0.899
0.837TyrTyr: 0.837 ± 0.641
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1196 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski