Lake Sarah-associated circular molecule 1

Taxonomy: Viruses; unclassified viruses

Average proteome isoelectric point is 9.19

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 1 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A126G993|A0A126G993_9VIRU Replication associated protein OS=Lake Sarah-associated circular molecule 1 OX=1685724 PE=4 SV=1
MM1 pKa = 7.81ADD3 pKa = 3.31YY4 pKa = 10.86AGKK7 pKa = 7.45TKK9 pKa = 10.8YY10 pKa = 9.71WIFVLKK16 pKa = 9.83TRR18 pKa = 11.84DD19 pKa = 3.54PARR22 pKa = 11.84SSIPIKK28 pKa = 10.22RR29 pKa = 11.84ATRR32 pKa = 11.84PTYY35 pKa = 10.21ATDD38 pKa = 3.22TKK40 pKa = 10.26SASRR44 pKa = 11.84ARR46 pKa = 11.84PHH48 pKa = 5.38LQGYY52 pKa = 9.79IEE54 pKa = 4.55MINRR58 pKa = 11.84KK59 pKa = 7.18TMIQMKK65 pKa = 10.1HH66 pKa = 6.74DD67 pKa = 3.68INPRR71 pKa = 11.84CKK73 pKa = 8.59WLPRR77 pKa = 11.84GGTALEE83 pKa = 3.91AATYY87 pKa = 9.97AKK89 pKa = 10.3KK90 pKa = 10.72DD91 pKa = 3.29NTGIYY96 pKa = 9.93EE97 pKa = 4.53DD98 pKa = 4.39GVLSKK103 pKa = 10.82SDD105 pKa = 3.13QGKK108 pKa = 9.71RR109 pKa = 11.84NDD111 pKa = 3.25MAEE114 pKa = 3.82IFKK117 pKa = 10.12MIEE120 pKa = 3.81NGADD124 pKa = 3.2EE125 pKa = 5.5ADD127 pKa = 3.34ICRR130 pKa = 11.84KK131 pKa = 10.14YY132 pKa = 9.66PGQFIRR138 pKa = 11.84YY139 pKa = 7.83HH140 pKa = 6.91AGITKK145 pKa = 10.33AISLQFQKK153 pKa = 10.65RR154 pKa = 11.84VGDD157 pKa = 3.43IEE159 pKa = 3.93IYY161 pKa = 10.45YY162 pKa = 9.89IYY164 pKa = 10.74GKK166 pKa = 8.41TGSGKK171 pKa = 8.62TSSVVKK177 pKa = 10.77KK178 pKa = 10.31EE179 pKa = 3.89GEE181 pKa = 4.25ALYY184 pKa = 8.55HH185 pKa = 6.78TYY187 pKa = 10.85DD188 pKa = 3.68QDD190 pKa = 4.19LRR192 pKa = 11.84WFDD195 pKa = 3.49GYY197 pKa = 11.18KK198 pKa = 10.05PSRR201 pKa = 11.84HH202 pKa = 5.0SAILIDD208 pKa = 4.51EE209 pKa = 4.68FNGSQKK215 pKa = 11.0AVFYY219 pKa = 11.27NKK221 pKa = 9.85ILDD224 pKa = 4.1RR225 pKa = 11.84YY226 pKa = 7.24TPWVEE231 pKa = 3.85VKK233 pKa = 10.13GAKK236 pKa = 9.63LRR238 pKa = 11.84ITAKK242 pKa = 10.3RR243 pKa = 11.84IYY245 pKa = 9.93ICSNYY250 pKa = 9.69KK251 pKa = 10.21LKK253 pKa = 10.77EE254 pKa = 3.9VANTQGWSPEE264 pKa = 3.64EE265 pKa = 3.74LEE267 pKa = 4.06QFKK270 pKa = 11.04RR271 pKa = 11.84RR272 pKa = 11.84VTKK275 pKa = 10.35FIHH278 pKa = 5.59VEE280 pKa = 4.02RR281 pKa = 11.84LPGAPPVDD289 pKa = 2.77IWAPLVPQAAEE300 pKa = 3.73PTTPVRR306 pKa = 11.84PQHH309 pKa = 4.77PHH311 pKa = 4.07GWRR314 pKa = 11.84QRR316 pKa = 11.84RR317 pKa = 11.84RR318 pKa = 11.84ATPPTCADD326 pKa = 3.91SACSGAPAGSRR337 pKa = 11.84HH338 pKa = 5.61SMRR341 pKa = 11.84VTNAPRR347 pKa = 11.84SGILCSRR354 pKa = 11.84SRR356 pKa = 11.84NRR358 pKa = 3.75

Molecular weight: 40.74 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A126G993|A0A126G993_9VIRU Replication associated protein OS=Lake Sarah-associated circular molecule 1 OX=1685724 PE=4 SV=1
MM1 pKa = 7.81ADD3 pKa = 3.31YY4 pKa = 10.86AGKK7 pKa = 7.45TKK9 pKa = 10.8YY10 pKa = 9.71WIFVLKK16 pKa = 9.83TRR18 pKa = 11.84DD19 pKa = 3.54PARR22 pKa = 11.84SSIPIKK28 pKa = 10.22RR29 pKa = 11.84ATRR32 pKa = 11.84PTYY35 pKa = 10.21ATDD38 pKa = 3.22TKK40 pKa = 10.26SASRR44 pKa = 11.84ARR46 pKa = 11.84PHH48 pKa = 5.38LQGYY52 pKa = 9.79IEE54 pKa = 4.55MINRR58 pKa = 11.84KK59 pKa = 7.18TMIQMKK65 pKa = 10.1HH66 pKa = 6.74DD67 pKa = 3.68INPRR71 pKa = 11.84CKK73 pKa = 8.59WLPRR77 pKa = 11.84GGTALEE83 pKa = 3.91AATYY87 pKa = 9.97AKK89 pKa = 10.3KK90 pKa = 10.72DD91 pKa = 3.29NTGIYY96 pKa = 9.93EE97 pKa = 4.53DD98 pKa = 4.39GVLSKK103 pKa = 10.82SDD105 pKa = 3.13QGKK108 pKa = 9.71RR109 pKa = 11.84NDD111 pKa = 3.25MAEE114 pKa = 3.82IFKK117 pKa = 10.12MIEE120 pKa = 3.81NGADD124 pKa = 3.2EE125 pKa = 5.5ADD127 pKa = 3.34ICRR130 pKa = 11.84KK131 pKa = 10.14YY132 pKa = 9.66PGQFIRR138 pKa = 11.84YY139 pKa = 7.83HH140 pKa = 6.91AGITKK145 pKa = 10.33AISLQFQKK153 pKa = 10.65RR154 pKa = 11.84VGDD157 pKa = 3.43IEE159 pKa = 3.93IYY161 pKa = 10.45YY162 pKa = 9.89IYY164 pKa = 10.74GKK166 pKa = 8.41TGSGKK171 pKa = 8.62TSSVVKK177 pKa = 10.77KK178 pKa = 10.31EE179 pKa = 3.89GEE181 pKa = 4.25ALYY184 pKa = 8.55HH185 pKa = 6.78TYY187 pKa = 10.85DD188 pKa = 3.68QDD190 pKa = 4.19LRR192 pKa = 11.84WFDD195 pKa = 3.49GYY197 pKa = 11.18KK198 pKa = 10.05PSRR201 pKa = 11.84HH202 pKa = 5.0SAILIDD208 pKa = 4.51EE209 pKa = 4.68FNGSQKK215 pKa = 11.0AVFYY219 pKa = 11.27NKK221 pKa = 9.85ILDD224 pKa = 4.1RR225 pKa = 11.84YY226 pKa = 7.24TPWVEE231 pKa = 3.85VKK233 pKa = 10.13GAKK236 pKa = 9.63LRR238 pKa = 11.84ITAKK242 pKa = 10.3RR243 pKa = 11.84IYY245 pKa = 9.93ICSNYY250 pKa = 9.69KK251 pKa = 10.21LKK253 pKa = 10.77EE254 pKa = 3.9VANTQGWSPEE264 pKa = 3.64EE265 pKa = 3.74LEE267 pKa = 4.06QFKK270 pKa = 11.04RR271 pKa = 11.84RR272 pKa = 11.84VTKK275 pKa = 10.35FIHH278 pKa = 5.59VEE280 pKa = 4.02RR281 pKa = 11.84LPGAPPVDD289 pKa = 2.77IWAPLVPQAAEE300 pKa = 3.73PTTPVRR306 pKa = 11.84PQHH309 pKa = 4.77PHH311 pKa = 4.07GWRR314 pKa = 11.84QRR316 pKa = 11.84RR317 pKa = 11.84RR318 pKa = 11.84ATPPTCADD326 pKa = 3.91SACSGAPAGSRR337 pKa = 11.84HH338 pKa = 5.61SMRR341 pKa = 11.84VTNAPRR347 pKa = 11.84SGILCSRR354 pKa = 11.84SRR356 pKa = 11.84NRR358 pKa = 3.75

Molecular weight: 40.74 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

1

0

1

358

358

358

358.0

40.74

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

8.939 ± 0.0

1.676 ± 0.0

5.028 ± 0.0

4.749 ± 0.0

2.514 ± 0.0

6.704 ± 0.0

2.514 ± 0.0

7.263 ± 0.0

8.38 ± 0.0

4.469 ± 0.0

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.955 ± 0.0

3.073 ± 0.0

6.425 ± 0.0

3.631 ± 0.0

8.939 ± 0.0

6.145 ± 0.0

6.425 ± 0.0

4.19 ± 0.0

1.955 ± 0.0

5.028 ± 0.0
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski