Amino acid dipepetide frequency for Hubei sobemo-like virus 5

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.903AlaAla: 6.903 ± 0.062
0.0AlaCys: 0.0 ± 0.0
1.972AlaAsp: 1.972 ± 0.752
1.972AlaGlu: 1.972 ± 0.752
2.959AlaPhe: 2.959 ± 0.271
3.945AlaGly: 3.945 ± 3.218
2.959AlaHis: 2.959 ± 1.985
0.986AlaIle: 0.986 ± 0.481
1.972AlaLys: 1.972 ± 0.962
10.848AlaLeu: 10.848 ± 3.576
2.959AlaMet: 2.959 ± 1.985
1.972AlaAsn: 1.972 ± 0.962
6.903AlaPro: 6.903 ± 0.062
5.917AlaGln: 5.917 ± 1.171
2.959AlaArg: 2.959 ± 1.443
5.917AlaSer: 5.917 ± 2.885
10.848AlaThr: 10.848 ± 3.28
5.917AlaVal: 5.917 ± 2.256
6.903AlaTrp: 6.903 ± 1.776
5.917AlaTyr: 5.917 ± 2.256
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.986CysAsp: 0.986 ± 0.481
1.972CysGlu: 1.972 ± 0.962
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.986CysHis: 0.986 ± 0.481
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.972CysLeu: 1.972 ± 0.962
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.972CysPro: 1.972 ± 0.752
0.0CysGln: 0.0 ± 0.0
0.986CysArg: 0.986 ± 0.481
0.986CysSer: 0.986 ± 1.233
0.986CysThr: 0.986 ± 1.233
0.986CysVal: 0.986 ± 0.481
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.945AspAla: 3.945 ± 1.504
0.986AspCys: 0.986 ± 1.233
3.945AspAsp: 3.945 ± 1.504
1.972AspGlu: 1.972 ± 0.962
2.959AspPhe: 2.959 ± 1.443
4.931AspGly: 4.931 ± 1.023
0.0AspHis: 0.0 ± 0.0
1.972AspIle: 1.972 ± 0.752
0.986AspLys: 0.986 ± 0.481
1.972AspLeu: 1.972 ± 2.466
0.986AspMet: 0.986 ± 1.233
1.972AspAsn: 1.972 ± 0.962
3.945AspPro: 3.945 ± 0.21
0.986AspGln: 0.986 ± 0.481
3.945AspArg: 3.945 ± 0.21
3.945AspSer: 3.945 ± 0.21
0.986AspThr: 0.986 ± 1.233
3.945AspVal: 3.945 ± 4.932
1.972AspTrp: 1.972 ± 0.752
1.972AspTyr: 1.972 ± 0.962
0.0AspXaa: 0.0 ± 0.0
Glu
5.917GluAla: 5.917 ± 2.885
0.986GluCys: 0.986 ± 1.233
4.931GluAsp: 4.931 ± 2.404
1.972GluGlu: 1.972 ± 0.752
2.959GluPhe: 2.959 ± 0.271
0.0GluGly: 0.0 ± 0.0
0.0GluHis: 0.0 ± 0.0
3.945GluIle: 3.945 ± 1.923
0.0GluLys: 0.0 ± 0.0
3.945GluLeu: 3.945 ± 1.923
1.972GluMet: 1.972 ± 0.503
4.931GluAsn: 4.931 ± 2.404
6.903GluPro: 6.903 ± 0.062
2.959GluGln: 2.959 ± 0.271
5.917GluArg: 5.917 ± 1.171
2.959GluSer: 2.959 ± 1.443
1.972GluThr: 1.972 ± 0.962
3.945GluVal: 3.945 ± 1.504
1.972GluTrp: 1.972 ± 0.962
0.986GluTyr: 0.986 ± 0.481
0.0GluXaa: 0.0 ± 0.0
Phe
2.959PheAla: 2.959 ± 1.985
0.0PheCys: 0.0 ± 0.0
2.959PheAsp: 2.959 ± 0.271
1.972PheGlu: 1.972 ± 0.962
0.0PhePhe: 0.0 ± 0.0
4.931PheGly: 4.931 ± 2.737
0.986PheHis: 0.986 ± 0.481
1.972PheIle: 1.972 ± 0.962
0.986PheLys: 0.986 ± 0.481
2.959PheLeu: 2.959 ± 0.271
0.986PheMet: 0.986 ± 0.481
0.986PheAsn: 0.986 ± 0.481
2.959PhePro: 2.959 ± 0.271
2.959PheGln: 2.959 ± 1.443
1.972PheArg: 1.972 ± 0.752
5.917PheSer: 5.917 ± 1.171
0.986PheThr: 0.986 ± 0.481
0.986PheVal: 0.986 ± 0.481
0.0PheTrp: 0.0 ± 0.0
0.986PheTyr: 0.986 ± 1.233
0.0PheXaa: 0.0 ± 0.0
Gly
3.945GlyAla: 3.945 ± 1.923
0.986GlyCys: 0.986 ± 0.481
2.959GlyAsp: 2.959 ± 1.985
0.986GlyGlu: 0.986 ± 0.481
5.917GlyPhe: 5.917 ± 0.543
1.972GlyGly: 1.972 ± 0.962
1.972GlyHis: 1.972 ± 0.962
4.931GlyIle: 4.931 ± 1.023
1.972GlyLys: 1.972 ± 0.752
4.931GlyLeu: 4.931 ± 1.023
3.945GlyMet: 3.945 ± 0.21
0.986GlyAsn: 0.986 ± 0.481
1.972GlyPro: 1.972 ± 0.752
1.972GlyGln: 1.972 ± 2.466
1.972GlyArg: 1.972 ± 0.962
10.848GlySer: 10.848 ± 1.566
2.959GlyThr: 2.959 ± 1.443
1.972GlyVal: 1.972 ± 0.752
1.972GlyTrp: 1.972 ± 2.466
1.972GlyTyr: 1.972 ± 0.752
0.0GlyXaa: 0.0 ± 0.0
His
0.986HisAla: 0.986 ± 1.233
0.986HisCys: 0.986 ± 0.481
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
3.945HisGly: 3.945 ± 0.21
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.986HisLys: 0.986 ± 1.233
2.959HisLeu: 2.959 ± 1.443
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
2.959HisPro: 2.959 ± 1.443
0.986HisGln: 0.986 ± 0.481
0.0HisArg: 0.0 ± 0.0
0.986HisSer: 0.986 ± 0.481
0.986HisThr: 0.986 ± 1.233
1.972HisVal: 1.972 ± 0.962
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
6.903IleAla: 6.903 ± 1.652
0.986IleCys: 0.986 ± 0.481
1.972IleAsp: 1.972 ± 2.466
2.959IleGlu: 2.959 ± 1.443
0.0IlePhe: 0.0 ± 0.0
0.986IleGly: 0.986 ± 0.481
0.986IleHis: 0.986 ± 0.481
2.959IleIle: 2.959 ± 0.271
0.986IleLys: 0.986 ± 0.481
1.972IleLeu: 1.972 ± 0.752
1.972IleMet: 1.972 ± 0.752
3.945IleAsn: 3.945 ± 0.21
0.986IlePro: 0.986 ± 1.233
3.945IleGln: 3.945 ± 1.923
1.972IleArg: 1.972 ± 0.962
1.972IleSer: 1.972 ± 0.962
2.959IleThr: 2.959 ± 1.985
0.0IleVal: 0.0 ± 0.0
0.0IleTrp: 0.0 ± 0.0
0.986IleTyr: 0.986 ± 1.233
0.0IleXaa: 0.0 ± 0.0
Lys
1.972LysAla: 1.972 ± 0.752
0.0LysCys: 0.0 ± 0.0
0.0LysAsp: 0.0 ± 0.0
2.959LysGlu: 2.959 ± 1.443
1.972LysPhe: 1.972 ± 0.752
1.972LysGly: 1.972 ± 0.962
1.972LysHis: 1.972 ± 0.752
0.986LysIle: 0.986 ± 0.481
2.959LysLys: 2.959 ± 1.443
2.959LysLeu: 2.959 ± 0.271
0.0LysMet: 0.0 ± 0.0
1.972LysAsn: 1.972 ± 0.962
0.0LysPro: 0.0 ± 0.0
0.0LysGln: 0.0 ± 0.0
0.986LysArg: 0.986 ± 1.233
1.972LysSer: 1.972 ± 2.466
1.972LysThr: 1.972 ± 0.962
0.986LysVal: 0.986 ± 0.481
0.0LysTrp: 0.0 ± 0.0
0.986LysTyr: 0.986 ± 1.233
0.0LysXaa: 0.0 ± 0.0
Leu
9.862LeuAla: 9.862 ± 3.761
0.986LeuCys: 0.986 ± 0.481
1.972LeuAsp: 1.972 ± 0.962
6.903LeuGlu: 6.903 ± 3.489
3.945LeuPhe: 3.945 ± 0.21
2.959LeuGly: 2.959 ± 0.271
0.986LeuHis: 0.986 ± 0.481
3.945LeuIle: 3.945 ± 0.21
4.931LeuLys: 4.931 ± 2.404
12.821LeuLeu: 12.821 ± 4.032
1.972LeuMet: 1.972 ± 0.752
3.945LeuAsn: 3.945 ± 0.21
3.945LeuPro: 3.945 ± 1.504
4.931LeuGln: 4.931 ± 0.69
6.903LeuArg: 6.903 ± 3.489
3.945LeuSer: 3.945 ± 1.504
8.876LeuThr: 8.876 ± 0.9
3.945LeuVal: 3.945 ± 1.504
1.972LeuTrp: 1.972 ± 0.752
2.959LeuTyr: 2.959 ± 0.271
0.0LeuXaa: 0.0 ± 0.0
Met
2.959MetAla: 2.959 ± 1.443
0.0MetCys: 0.0 ± 0.0
0.986MetAsp: 0.986 ± 0.481
1.972MetGlu: 1.972 ± 0.752
0.986MetPhe: 0.986 ± 0.481
2.959MetGly: 2.959 ± 1.985
0.0MetHis: 0.0 ± 0.0
0.986MetIle: 0.986 ± 1.233
0.986MetLys: 0.986 ± 1.233
4.931MetLeu: 4.931 ± 0.69
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
0.986MetGln: 0.986 ± 0.481
1.972MetArg: 1.972 ± 0.752
0.0MetSer: 0.0 ± 0.0
1.972MetThr: 1.972 ± 0.962
0.986MetVal: 0.986 ± 1.233
0.986MetTrp: 0.986 ± 0.481
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.945AsnAla: 3.945 ± 1.923
1.972AsnCys: 1.972 ± 0.752
0.986AsnAsp: 0.986 ± 0.481
1.972AsnGlu: 1.972 ± 0.962
0.0AsnPhe: 0.0 ± 0.0
1.972AsnGly: 1.972 ± 0.752
1.972AsnHis: 1.972 ± 0.962
0.0AsnIle: 0.0 ± 0.0
0.986AsnLys: 0.986 ± 1.233
0.986AsnLeu: 0.986 ± 1.233
0.0AsnMet: 0.0 ± 0.0
4.931AsnAsn: 4.931 ± 2.404
2.959AsnPro: 2.959 ± 0.271
0.986AsnGln: 0.986 ± 0.481
2.959AsnArg: 2.959 ± 1.443
3.945AsnSer: 3.945 ± 0.21
3.945AsnThr: 3.945 ± 1.923
1.972AsnVal: 1.972 ± 0.962
0.0AsnTrp: 0.0 ± 0.0
1.972AsnTyr: 1.972 ± 0.962
0.0AsnXaa: 0.0 ± 0.0
Pro
3.945ProAla: 3.945 ± 0.21
0.0ProCys: 0.0 ± 0.0
6.903ProAsp: 6.903 ± 3.489
7.89ProGlu: 7.89 ± 3.847
0.0ProPhe: 0.0 ± 0.0
5.917ProGly: 5.917 ± 1.171
0.0ProHis: 0.0 ± 0.0
1.972ProIle: 1.972 ± 0.752
0.986ProLys: 0.986 ± 0.481
6.903ProLeu: 6.903 ± 5.203
0.986ProMet: 0.986 ± 0.481
3.945ProAsn: 3.945 ± 1.504
3.945ProPro: 3.945 ± 1.923
1.972ProGln: 1.972 ± 2.466
3.945ProArg: 3.945 ± 1.923
8.876ProSer: 8.876 ± 2.614
3.945ProThr: 3.945 ± 1.923
2.959ProVal: 2.959 ± 1.443
1.972ProTrp: 1.972 ± 0.752
0.986ProTyr: 0.986 ± 0.481
0.0ProXaa: 0.0 ± 0.0
Gln
2.959GlnAla: 2.959 ± 1.443
1.972GlnCys: 1.972 ± 0.962
2.959GlnAsp: 2.959 ± 1.985
2.959GlnGlu: 2.959 ± 1.443
2.959GlnPhe: 2.959 ± 1.443
2.959GlnGly: 2.959 ± 0.271
0.986GlnHis: 0.986 ± 0.481
0.0GlnIle: 0.0 ± 0.0
0.0GlnLys: 0.0 ± 0.0
5.917GlnLeu: 5.917 ± 0.543
1.972GlnMet: 1.972 ± 0.752
1.972GlnAsn: 1.972 ± 0.962
5.917GlnPro: 5.917 ± 2.885
9.862GlnGln: 9.862 ± 3.095
3.945GlnArg: 3.945 ± 0.21
5.917GlnSer: 5.917 ± 1.171
4.931GlnThr: 4.931 ± 0.69
0.0GlnVal: 0.0 ± 0.0
0.0GlnTrp: 0.0 ± 0.0
1.972GlnTyr: 1.972 ± 0.752
0.0GlnXaa: 0.0 ± 0.0
Arg
7.89ArgAla: 7.89 ± 3.009
0.0ArgCys: 0.0 ± 0.0
2.959ArgAsp: 2.959 ± 1.443
5.917ArgGlu: 5.917 ± 1.171
0.986ArgPhe: 0.986 ± 0.481
2.959ArgGly: 2.959 ± 1.443
0.0ArgHis: 0.0 ± 0.0
2.959ArgIle: 2.959 ± 0.271
0.0ArgLys: 0.0 ± 0.0
7.89ArgLeu: 7.89 ± 0.419
0.0ArgMet: 0.0 ± 0.0
1.972ArgAsn: 1.972 ± 0.962
2.959ArgPro: 2.959 ± 1.443
4.931ArgGln: 4.931 ± 1.023
6.903ArgArg: 6.903 ± 0.062
3.945ArgSer: 3.945 ± 1.923
4.931ArgThr: 4.931 ± 1.023
4.931ArgVal: 4.931 ± 0.69
2.959ArgTrp: 2.959 ± 1.985
0.986ArgTyr: 0.986 ± 0.481
0.0ArgXaa: 0.0 ± 0.0
Ser
7.89SerAla: 7.89 ± 3.009
0.0SerCys: 0.0 ± 0.0
4.931SerAsp: 4.931 ± 1.023
3.945SerGlu: 3.945 ± 0.21
2.959SerPhe: 2.959 ± 3.699
7.89SerGly: 7.89 ± 1.295
1.972SerHis: 1.972 ± 0.752
1.972SerIle: 1.972 ± 0.962
1.972SerLys: 1.972 ± 0.752
4.931SerLeu: 4.931 ± 1.023
2.959SerMet: 2.959 ± 1.244
1.972SerAsn: 1.972 ± 0.962
7.89SerPro: 7.89 ± 3.847
5.917SerGln: 5.917 ± 2.885
7.89SerArg: 7.89 ± 0.419
13.807SerSer: 13.807 ± 5.018
4.931SerThr: 4.931 ± 2.404
0.986SerVal: 0.986 ± 0.481
0.986SerTrp: 0.986 ± 0.481
4.931SerTyr: 4.931 ± 2.404
0.0SerXaa: 0.0 ± 0.0
Thr
10.848ThrAla: 10.848 ± 0.148
0.0ThrCys: 0.0 ± 0.0
2.959ThrAsp: 2.959 ± 1.985
5.917ThrGlu: 5.917 ± 1.171
2.959ThrPhe: 2.959 ± 1.443
4.931ThrGly: 4.931 ± 1.023
0.0ThrHis: 0.0 ± 0.0
1.972ThrIle: 1.972 ± 0.752
0.0ThrLys: 0.0 ± 0.0
2.959ThrLeu: 2.959 ± 1.985
1.972ThrMet: 1.972 ± 0.962
0.0ThrAsn: 0.0 ± 0.0
5.917ThrPro: 5.917 ± 1.171
2.959ThrGln: 2.959 ± 1.443
4.931ThrArg: 4.931 ± 0.69
6.903ThrSer: 6.903 ± 0.062
2.959ThrThr: 2.959 ± 0.271
2.959ThrVal: 2.959 ± 1.443
0.0ThrTrp: 0.0 ± 0.0
2.959ThrTyr: 2.959 ± 0.271
0.0ThrXaa: 0.0 ± 0.0
Val
0.0ValAla: 0.0 ± 0.0
0.986ValCys: 0.986 ± 0.481
1.972ValAsp: 1.972 ± 0.752
1.972ValGlu: 1.972 ± 0.962
1.972ValPhe: 1.972 ± 0.962
0.986ValGly: 0.986 ± 0.481
0.986ValHis: 0.986 ± 0.481
4.931ValIle: 4.931 ± 1.023
3.945ValLys: 3.945 ± 3.218
6.903ValLeu: 6.903 ± 3.489
0.0ValMet: 0.0 ± 0.0
2.959ValAsn: 2.959 ± 1.985
1.972ValPro: 1.972 ± 0.752
3.945ValGln: 3.945 ± 0.21
2.959ValArg: 2.959 ± 0.271
2.959ValSer: 2.959 ± 1.443
1.972ValThr: 1.972 ± 0.962
2.959ValVal: 2.959 ± 1.443
0.986ValTrp: 0.986 ± 0.481
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
3.945TrpAla: 3.945 ± 1.504
0.0TrpCys: 0.0 ± 0.0
0.986TrpAsp: 0.986 ± 0.481
2.959TrpGlu: 2.959 ± 1.443
1.972TrpPhe: 1.972 ± 0.752
1.972TrpGly: 1.972 ± 0.962
0.0TrpHis: 0.0 ± 0.0
0.986TrpIle: 0.986 ± 0.481
0.0TrpLys: 0.0 ± 0.0
1.972TrpLeu: 1.972 ± 0.752
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
1.972TrpPro: 1.972 ± 2.466
0.986TrpGln: 0.986 ± 0.481
1.972TrpArg: 1.972 ± 0.962
2.959TrpSer: 2.959 ± 1.985
0.986TrpThr: 0.986 ± 1.233
0.986TrpVal: 0.986 ± 1.233
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.959TyrAla: 2.959 ± 1.985
0.986TyrCys: 0.986 ± 0.481
0.986TyrAsp: 0.986 ± 1.233
0.986TyrGlu: 0.986 ± 0.481
2.959TyrPhe: 2.959 ± 0.271
2.959TyrGly: 2.959 ± 0.271
0.986TyrHis: 0.986 ± 0.481
1.972TyrIle: 1.972 ± 0.962
1.972TyrLys: 1.972 ± 0.962
1.972TyrLeu: 1.972 ± 0.752
0.0TyrMet: 0.0 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
1.972TyrPro: 1.972 ± 2.466
2.959TyrGln: 2.959 ± 1.443
0.986TyrArg: 0.986 ± 1.233
1.972TyrSer: 1.972 ± 0.752
0.0TyrThr: 0.0 ± 0.0
1.972TyrVal: 1.972 ± 0.962
1.972TyrTrp: 1.972 ± 0.962
1.972TyrTyr: 1.972 ± 0.962
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1015 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski