Amino acid dipepetide frequency for Taenia asiatica (Asian tapeworm)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.705AlaAla: 7.705 ± 0.082	1.518AlaCys: 1.518 ± 0.021	3.589AlaAsp: 3.589 ± 0.032	4.732AlaGlu: 4.732 ± 0.048	3.138AlaPhe: 3.138 ± 0.027	4.05AlaGly: 4.05 ± 0.039	1.572AlaHis: 1.572 ± 0.017	3.691AlaIle: 3.691 ± 0.031	3.583AlaLys: 3.583 ± 0.035	7.142AlaLeu: 7.142 ± 0.045	1.688AlaMet: 1.688 ± 0.02	3.026AlaAsn: 3.026 ± 0.025	3.899AlaPro: 3.899 ± 0.039	2.557AlaGln: 2.557 ± 0.027	3.91AlaArg: 3.91 ± 0.032	7.347AlaSer: 7.347 ± 0.052	4.907AlaThr: 4.907 ± 0.042	5.281AlaVal: 5.281 ± 0.036	0.747AlaTrp: 0.747 ± 0.013	1.973AlaTyr: 1.973 ± 0.025	0.002AlaXaa: 0.002 ± 0.001
Cys	1.336CysAla: 1.336 ± 0.02	0.621CysCys: 0.621 ± 0.014	1.05CysAsp: 1.05 ± 0.018	1.214CysGlu: 1.214 ± 0.019	0.911CysPhe: 0.911 ± 0.014	1.417CysGly: 1.417 ± 0.023	0.576CysHis: 0.576 ± 0.011	1.109CysIle: 1.109 ± 0.018	0.858CysLys: 0.858 ± 0.017	2.48CysLeu: 2.48 ± 0.029	0.404CysMet: 0.404 ± 0.009	0.748CysAsn: 0.748 ± 0.014	1.178CysPro: 1.178 ± 0.023	0.831CysGln: 0.831 ± 0.014	1.373CysArg: 1.373 ± 0.02	1.796CysSer: 1.796 ± 0.02	1.042CysThr: 1.042 ± 0.018	1.409CysVal: 1.409 ± 0.02	0.227CysTrp: 0.227 ± 0.008	0.545CysTyr: 0.545 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	3.917AspAla: 3.917 ± 0.03	1.031AspCys: 1.031 ± 0.018	3.246AspAsp: 3.246 ± 0.05	3.871AspGlu: 3.871 ± 0.037	2.322AspPhe: 2.322 ± 0.025	3.335AspGly: 3.335 ± 0.045	1.026AspHis: 1.026 ± 0.017	2.524AspIle: 2.524 ± 0.025	2.045AspLys: 2.045 ± 0.027	5.159AspLeu: 5.159 ± 0.036	1.0AspMet: 1.0 ± 0.016	1.806AspAsn: 1.806 ± 0.021	2.631AspPro: 2.631 ± 0.027	1.609AspGln: 1.609 ± 0.02	2.707AspArg: 2.707 ± 0.028	4.187AspSer: 4.187 ± 0.035	2.41AspThr: 2.41 ± 0.021	3.531AspVal: 3.531 ± 0.032	0.64AspTrp: 0.64 ± 0.013	1.506AspTyr: 1.506 ± 0.022	0.0AspXaa: 0.0 ± 0.0
Glu	5.456GluAla: 5.456 ± 0.043	1.168GluCys: 1.168 ± 0.018	3.631GluAsp: 3.631 ± 0.036	6.217GluGlu: 6.217 ± 0.079	2.135GluPhe: 2.135 ± 0.024	3.631GluGly: 3.631 ± 0.033	1.291GluHis: 1.291 ± 0.015	3.038GluIle: 3.038 ± 0.032	3.608GluLys: 3.608 ± 0.038	5.463GluLeu: 5.463 ± 0.044	1.628GluMet: 1.628 ± 0.019	2.578GluAsn: 2.578 ± 0.028	2.436GluPro: 2.436 ± 0.032	2.231GluGln: 2.231 ± 0.025	3.77GluArg: 3.77 ± 0.034	4.584GluSer: 4.584 ± 0.035	3.319GluThr: 3.319 ± 0.029	4.537GluVal: 4.537 ± 0.043	0.66GluTrp: 0.66 ± 0.014	1.481GluTyr: 1.481 ± 0.02	0.001GluXaa: 0.001 ± 0.0
Phe	2.818PheAla: 2.818 ± 0.027	0.978PheCys: 0.978 ± 0.015	2.234PheAsp: 2.234 ± 0.025	2.207PheGlu: 2.207 ± 0.023	1.868PhePhe: 1.868 ± 0.025	2.366PheGly: 2.366 ± 0.029	1.069PheHis: 1.069 ± 0.015	2.045PheIle: 2.045 ± 0.023	1.663PheLys: 1.663 ± 0.021	3.984PheLeu: 3.984 ± 0.04	0.801PheMet: 0.801 ± 0.013	1.627PheAsn: 1.627 ± 0.02	1.943PhePro: 1.943 ± 0.022	1.393PheGln: 1.393 ± 0.019	2.239PheArg: 2.239 ± 0.023	3.508PheSer: 3.508 ± 0.031	2.354PheThr: 2.354 ± 0.023	2.721PheVal: 2.721 ± 0.027	0.453PheTrp: 0.453 ± 0.012	1.328PheTyr: 1.328 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	4.015GlyAla: 4.015 ± 0.034	1.235GlyCys: 1.235 ± 0.022	3.307GlyAsp: 3.307 ± 0.036	3.725GlyGlu: 3.725 ± 0.055	2.321GlyPhe: 2.321 ± 0.027	5.705GlyGly: 5.705 ± 0.074	1.352GlyHis: 1.352 ± 0.019	2.761GlyIle: 2.761 ± 0.034	2.775GlyLys: 2.775 ± 0.031	5.168GlyLeu: 5.168 ± 0.039	1.217GlyMet: 1.217 ± 0.015	2.247GlyAsn: 2.247 ± 0.022	2.662GlyPro: 2.662 ± 0.092	2.006GlyGln: 2.006 ± 0.025	3.628GlyArg: 3.628 ± 0.037	5.27GlySer: 5.27 ± 0.045	3.115GlyThr: 3.115 ± 0.027	4.066GlyVal: 4.066 ± 0.033	0.641GlyTrp: 0.641 ± 0.012	1.581GlyTyr: 1.581 ± 0.023	0.0GlyXaa: 0.0 ± 0.0
His	1.473HisAla: 1.473 ± 0.016	0.63HisCys: 0.63 ± 0.013	0.958HisAsp: 0.958 ± 0.015	1.235HisGlu: 1.235 ± 0.017	1.181HisPhe: 1.181 ± 0.015	1.261HisGly: 1.261 ± 0.016	1.029HisHis: 1.029 ± 0.026	1.168HisIle: 1.168 ± 0.015	0.929HisLys: 0.929 ± 0.014	2.973HisLeu: 2.973 ± 0.026	0.478HisMet: 0.478 ± 0.01	0.847HisAsn: 0.847 ± 0.013	1.639HisPro: 1.639 ± 0.021	1.231HisGln: 1.231 ± 0.019	1.826HisArg: 1.826 ± 0.022	2.187HisSer: 2.187 ± 0.024	1.203HisThr: 1.203 ± 0.019	1.373HisVal: 1.373 ± 0.017	0.323HisTrp: 0.323 ± 0.008	0.739HisTyr: 0.739 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	3.658IleAla: 3.658 ± 0.03	1.201IleCys: 1.201 ± 0.019	2.666IleAsp: 2.666 ± 0.026	2.82IleGlu: 2.82 ± 0.029	2.182IlePhe: 2.182 ± 0.026	2.714IleGly: 2.714 ± 0.03	1.214IleHis: 1.214 ± 0.016	2.451IleIle: 2.451 ± 0.027	2.166IleLys: 2.166 ± 0.021	4.627IleLeu: 4.627 ± 0.036	0.919IleMet: 0.919 ± 0.014	1.999IleAsn: 1.999 ± 0.02	2.739IlePro: 2.739 ± 0.03	1.818IleGln: 1.818 ± 0.024	2.894IleArg: 2.894 ± 0.025	4.274IleSer: 4.274 ± 0.03	2.816IleThr: 2.816 ± 0.027	3.087IleVal: 3.087 ± 0.027	0.529IleTrp: 0.529 ± 0.011	1.457IleTyr: 1.457 ± 0.021	0.0IleXaa: 0.0 ± 0.0
Lys	3.564LysAla: 3.564 ± 0.033	0.9LysCys: 0.9 ± 0.017	2.174LysAsp: 2.174 ± 0.028	3.276LysGlu: 3.276 ± 0.036	1.585LysPhe: 1.585 ± 0.019	2.291LysGly: 2.291 ± 0.037	1.125LysHis: 1.125 ± 0.018	2.259LysIle: 2.259 ± 0.026	3.046LysLys: 3.046 ± 0.048	4.377LysLeu: 4.377 ± 0.039	1.19LysMet: 1.19 ± 0.019	1.848LysAsn: 1.848 ± 0.024	2.517LysPro: 2.517 ± 0.03	1.905LysGln: 1.905 ± 0.021	3.555LysArg: 3.555 ± 0.032	3.968LysSer: 3.968 ± 0.033	2.612LysThr: 2.612 ± 0.027	2.989LysVal: 2.989 ± 0.031	0.515LysTrp: 0.515 ± 0.011	1.232LysTyr: 1.232 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	7.322LeuAla: 7.322 ± 0.051	2.054LeuCys: 2.054 ± 0.024	4.769LeuAsp: 4.769 ± 0.039	5.96LeuGlu: 5.96 ± 0.057	3.857LeuPhe: 3.857 ± 0.036	4.769LeuGly: 4.769 ± 0.034	2.657LeuHis: 2.657 ± 0.026	4.779LeuIle: 4.779 ± 0.039	4.809LeuLys: 4.809 ± 0.037	10.57LeuLeu: 10.57 ± 0.082	2.045LeuMet: 2.045 ± 0.018	3.889LeuAsn: 3.889 ± 0.031	6.196LeuPro: 6.196 ± 0.047	4.417LeuGln: 4.417 ± 0.037	6.655LeuArg: 6.655 ± 0.045	8.483LeuSer: 8.483 ± 0.047	5.65LeuThr: 5.65 ± 0.036	5.986LeuVal: 5.986 ± 0.043	1.008LeuTrp: 1.008 ± 0.017	2.359LeuTyr: 2.359 ± 0.024	0.001LeuXaa: 0.001 ± 0.0
Met	1.795MetAla: 1.795 ± 0.021	0.4MetCys: 0.4 ± 0.01	1.223MetAsp: 1.223 ± 0.015	1.622MetGlu: 1.622 ± 0.02	0.664MetPhe: 0.664 ± 0.012	1.245MetGly: 1.245 ± 0.017	0.533MetHis: 0.533 ± 0.009	0.876MetIle: 0.876 ± 0.013	1.098MetLys: 1.098 ± 0.016	2.028MetLeu: 2.028 ± 0.023	0.503MetMet: 0.503 ± 0.011	0.86MetAsn: 0.86 ± 0.015	1.208MetPro: 1.208 ± 0.017	0.935MetGln: 0.935 ± 0.015	1.433MetArg: 1.433 ± 0.017	1.706MetSer: 1.706 ± 0.021	1.193MetThr: 1.193 ± 0.016	1.35MetVal: 1.35 ± 0.018	0.214MetTrp: 0.214 ± 0.007	0.475MetTyr: 0.475 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.147AsnAla: 3.147 ± 0.028	0.853AsnCys: 0.853 ± 0.016	1.952AsnAsp: 1.952 ± 0.022	2.411AsnGlu: 2.411 ± 0.027	1.696AsnPhe: 1.696 ± 0.021	2.645AsnGly: 2.645 ± 0.032	0.94AsnHis: 0.94 ± 0.014	1.901AsnIle: 1.901 ± 0.02	1.6AsnLys: 1.6 ± 0.023	3.995AsnLeu: 3.995 ± 0.033	0.76AsnMet: 0.76 ± 0.013	1.584AsnAsn: 1.584 ± 0.022	2.222AsnPro: 2.222 ± 0.022	1.548AsnGln: 1.548 ± 0.017	2.363AsnArg: 2.363 ± 0.022	3.434AsnSer: 3.434 ± 0.029	2.127AsnThr: 2.127 ± 0.021	2.516AsnVal: 2.516 ± 0.021	0.47AsnTrp: 0.47 ± 0.011	1.158AsnTyr: 1.158 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	3.653ProAla: 3.653 ± 0.033	0.969ProCys: 0.969 ± 0.019	2.57ProAsp: 2.57 ± 0.032	3.103ProGlu: 3.103 ± 0.031	2.099ProPhe: 2.099 ± 0.023	2.934ProGly: 2.934 ± 0.073	1.412ProHis: 1.412 ± 0.018	2.699ProIle: 2.699 ± 0.031	2.471ProLys: 2.471 ± 0.031	5.513ProLeu: 5.513 ± 0.044	1.114ProMet: 1.114 ± 0.018	2.219ProAsn: 2.219 ± 0.024	6.438ProPro: 6.438 ± 0.093	2.383ProGln: 2.383 ± 0.032	3.134ProArg: 3.134 ± 0.034	6.311ProSer: 6.311 ± 0.052	3.945ProThr: 3.945 ± 0.034	3.467ProVal: 3.467 ± 0.033	0.533ProTrp: 0.533 ± 0.011	1.324ProTyr: 1.324 ± 0.019	0.0ProXaa: 0.0 ± 0.0
Gln	2.752GlnAla: 2.752 ± 0.029	0.781GlnCys: 0.781 ± 0.017	1.439GlnAsp: 1.439 ± 0.018	2.218GlnGlu: 2.218 ± 0.023	1.364GlnPhe: 1.364 ± 0.018	1.693GlnGly: 1.693 ± 0.029	1.192GlnHis: 1.192 ± 0.018	1.927GlnIle: 1.927 ± 0.021	1.932GlnLys: 1.932 ± 0.025	4.245GlnLeu: 4.245 ± 0.038	1.075GlnMet: 1.075 ± 0.015	1.555GlnAsn: 1.555 ± 0.021	2.491GlnPro: 2.491 ± 0.038	3.069GlnGln: 3.069 ± 0.072	2.926GlnArg: 2.926 ± 0.029	3.334GlnSer: 3.334 ± 0.032	2.232GlnThr: 2.232 ± 0.022	2.295GlnVal: 2.295 ± 0.023	0.478GlnTrp: 0.478 ± 0.01	0.897GlnTyr: 0.897 ± 0.013	0.0GlnXaa: 0.0 ± 0.0
Arg	3.916ArgAla: 3.916 ± 0.034	1.42ArgCys: 1.42 ± 0.017	2.746ArgAsp: 2.746 ± 0.025	3.52ArgGlu: 3.52 ± 0.033	2.518ArgPhe: 2.518 ± 0.024	3.439ArgGly: 3.439 ± 0.041	1.795ArgHis: 1.795 ± 0.022	3.193ArgIle: 3.193 ± 0.028	3.249ArgLys: 3.249 ± 0.032	7.034ArgLeu: 7.034 ± 0.052	1.39ArgMet: 1.39 ± 0.016	2.393ArgAsn: 2.393 ± 0.025	3.192ArgPro: 3.192 ± 0.03	2.82ArgGln: 2.82 ± 0.024	5.639ArgArg: 5.639 ± 0.049	5.225ArgSer: 5.225 ± 0.041	2.998ArgThr: 2.998 ± 0.028	3.706ArgVal: 3.706 ± 0.028	0.758ArgTrp: 0.758 ± 0.013	1.665ArgTyr: 1.665 ± 0.02	0.001ArgXaa: 0.001 ± 0.0
Ser	6.872SerAla: 6.872 ± 0.049	1.702SerCys: 1.702 ± 0.02	4.376SerAsp: 4.376 ± 0.039	4.847SerGlu: 4.847 ± 0.041	3.164SerPhe: 3.164 ± 0.029	5.842SerGly: 5.842 ± 0.049	2.109SerHis: 2.109 ± 0.021	4.112SerIle: 4.112 ± 0.032	3.937SerLys: 3.937 ± 0.038	8.529SerLeu: 8.529 ± 0.045	1.803SerMet: 1.803 ± 0.02	3.506SerAsn: 3.506 ± 0.026	5.725SerPro: 5.725 ± 0.051	3.428SerGln: 3.428 ± 0.032	5.318SerArg: 5.318 ± 0.039	10.874SerSer: 10.874 ± 0.106	6.363SerThr: 6.363 ± 0.051	5.712SerVal: 5.712 ± 0.037	0.851SerTrp: 0.851 ± 0.014	1.904SerTyr: 1.904 ± 0.022	0.001SerXaa: 0.001 ± 0.0
Thr	4.992ThrAla: 4.992 ± 0.045	1.207ThrCys: 1.207 ± 0.021	2.846ThrAsp: 2.846 ± 0.026	3.33ThrGlu: 3.33 ± 0.029	2.253ThrPhe: 2.253 ± 0.024	3.47ThrGly: 3.47 ± 0.03	1.269ThrHis: 1.269 ± 0.017	2.688ThrIle: 2.688 ± 0.024	2.48ThrLys: 2.48 ± 0.025	5.22ThrLeu: 5.22 ± 0.04	1.158ThrMet: 1.158 ± 0.016	2.357ThrAsn: 2.357 ± 0.025	3.863ThrPro: 3.863 ± 0.036	1.982ThrGln: 1.982 ± 0.023	2.966ThrArg: 2.966 ± 0.027	6.116ThrSer: 6.116 ± 0.049	4.557ThrThr: 4.557 ± 0.053	3.902ThrVal: 3.902 ± 0.031	0.605ThrTrp: 0.605 ± 0.012	1.447ThrTyr: 1.447 ± 0.021	0.0ThrXaa: 0.0 ± 0.0
Val	5.175ValAla: 5.175 ± 0.038	1.556ValCys: 1.556 ± 0.021	3.842ValAsp: 3.842 ± 0.032	4.458ValGlu: 4.458 ± 0.037	2.616ValPhe: 2.616 ± 0.025	3.938ValGly: 3.938 ± 0.035	1.497ValHis: 1.497 ± 0.019	3.117ValIle: 3.117 ± 0.028	3.052ValLys: 3.052 ± 0.029	5.733ValLeu: 5.733 ± 0.037	1.335ValMet: 1.335 ± 0.017	2.728ValAsn: 2.728 ± 0.025	3.422ValPro: 3.422 ± 0.028	2.278ValGln: 2.278 ± 0.025	3.62ValArg: 3.62 ± 0.029	5.431ValSer: 5.431 ± 0.036	3.835ValThr: 3.835 ± 0.036	4.691ValVal: 4.691 ± 0.032	0.701ValTrp: 0.701 ± 0.014	1.816ValTyr: 1.816 ± 0.02	0.001ValXaa: 0.001 ± 0.0
Trp	0.612TrpAla: 0.612 ± 0.012	0.264TrpCys: 0.264 ± 0.008	0.541TrpAsp: 0.541 ± 0.014	0.556TrpGlu: 0.556 ± 0.011	0.459TrpPhe: 0.459 ± 0.011	0.48TrpGly: 0.48 ± 0.011	0.291TrpHis: 0.291 ± 0.008	0.628TrpIle: 0.628 ± 0.012	0.563TrpLys: 0.563 ± 0.012	1.17TrpLeu: 1.17 ± 0.018	0.309TrpMet: 0.309 ± 0.009	0.499TrpAsn: 0.499 ± 0.01	0.541TrpPro: 0.541 ± 0.01	0.439TrpGln: 0.439 ± 0.01	0.878TrpArg: 0.878 ± 0.014	0.94TrpSer: 0.94 ± 0.015	0.618TrpThr: 0.618 ± 0.013	0.6TrpVal: 0.6 ± 0.014	0.165TrpTrp: 0.165 ± 0.007	0.298TrpTyr: 0.298 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.879TyrAla: 1.879 ± 0.02	0.638TyrCys: 0.638 ± 0.014	1.345TyrAsp: 1.345 ± 0.02	1.54TyrGlu: 1.54 ± 0.018	1.266TyrPhe: 1.266 ± 0.016	1.57TyrGly: 1.57 ± 0.021	0.736TyrHis: 0.736 ± 0.013	1.264TyrIle: 1.264 ± 0.018	1.064TyrLys: 1.064 ± 0.016	2.828TyrLeu: 2.828 ± 0.025	0.544TyrMet: 0.544 ± 0.012	1.007TyrAsn: 1.007 ± 0.016	1.351TyrPro: 1.351 ± 0.019	1.012TyrGln: 1.012 ± 0.015	1.78TyrArg: 1.78 ± 0.023	1.996TyrSer: 1.996 ± 0.023	1.411TyrThr: 1.411 ± 0.018	1.621TyrVal: 1.621 ± 0.02	0.332TyrTrp: 0.332 ± 0.009	0.882TyrTyr: 0.882 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.001XaaLeu: 0.001 ± 0.0	0.001XaaMet: 0.001 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.001XaaThr: 0.001 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.001XaaTrp: 0.001 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.037XaaXaa: 0.037 ± 0.009

Statistics based on 10244 proteins (4944211 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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