Amino acid dipepetide frequency for Bovine adenovirus 6

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.193AlaAla: 5.193 ± 0.965
0.903AlaCys: 0.903 ± 0.304
2.258AlaAsp: 2.258 ± 0.48
3.048AlaGlu: 3.048 ± 0.561
2.822AlaPhe: 2.822 ± 0.592
2.371AlaGly: 2.371 ± 0.601
0.903AlaHis: 0.903 ± 0.365
4.064AlaIle: 4.064 ± 0.52
3.387AlaLys: 3.387 ± 0.688
5.532AlaLeu: 5.532 ± 0.828
1.58AlaMet: 1.58 ± 0.622
2.822AlaAsn: 2.822 ± 0.66
2.935AlaPro: 2.935 ± 0.576
2.597AlaGln: 2.597 ± 0.584
2.484AlaArg: 2.484 ± 0.755
3.387AlaSer: 3.387 ± 0.608
2.709AlaThr: 2.709 ± 0.618
2.484AlaVal: 2.484 ± 0.592
0.564AlaTrp: 0.564 ± 0.222
2.032AlaTyr: 2.032 ± 0.739
0.0AlaXaa: 0.0 ± 0.0
Cys
0.677CysAla: 0.677 ± 0.362
0.903CysCys: 0.903 ± 0.563
1.016CysAsp: 1.016 ± 0.371
1.693CysGlu: 1.693 ± 0.579
1.468CysPhe: 1.468 ± 0.389
1.58CysGly: 1.58 ± 0.494
1.129CysHis: 1.129 ± 0.438
1.468CysIle: 1.468 ± 0.488
2.258CysLys: 2.258 ± 0.63
2.145CysLeu: 2.145 ± 0.718
0.564CysMet: 0.564 ± 0.288
1.58CysAsn: 1.58 ± 0.362
0.903CysPro: 0.903 ± 0.464
0.564CysGln: 0.564 ± 0.246
0.452CysArg: 0.452 ± 0.24
2.371CysSer: 2.371 ± 0.485
0.564CysThr: 0.564 ± 0.226
1.355CysVal: 1.355 ± 0.6
0.113CysTrp: 0.113 ± 0.097
0.903CysTyr: 0.903 ± 0.369
0.0CysXaa: 0.0 ± 0.0
Asp
2.709AspAla: 2.709 ± 0.458
0.903AspCys: 0.903 ± 0.251
2.484AspAsp: 2.484 ± 0.391
3.5AspGlu: 3.5 ± 0.576
2.371AspPhe: 2.371 ± 0.672
1.919AspGly: 1.919 ± 0.469
0.79AspHis: 0.79 ± 0.332
3.838AspIle: 3.838 ± 0.83
2.484AspLys: 2.484 ± 0.613
4.177AspLeu: 4.177 ± 0.596
1.355AspMet: 1.355 ± 0.391
2.822AspAsn: 2.822 ± 0.725
2.371AspPro: 2.371 ± 0.506
1.129AspGln: 1.129 ± 0.301
2.484AspArg: 2.484 ± 0.613
2.935AspSer: 2.935 ± 0.47
3.048AspThr: 3.048 ± 0.481
2.258AspVal: 2.258 ± 0.531
0.564AspTrp: 0.564 ± 0.249
2.371AspTyr: 2.371 ± 0.468
0.0AspXaa: 0.0 ± 0.0
Glu
2.371GluAla: 2.371 ± 0.568
1.58GluCys: 1.58 ± 0.507
3.274GluAsp: 3.274 ± 0.617
5.419GluGlu: 5.419 ± 0.967
2.484GluPhe: 2.484 ± 0.578
2.709GluGly: 2.709 ± 0.771
0.677GluHis: 0.677 ± 0.234
3.725GluIle: 3.725 ± 0.7
5.645GluLys: 5.645 ± 1.163
4.177GluLeu: 4.177 ± 0.567
1.468GluMet: 1.468 ± 0.469
4.516GluAsn: 4.516 ± 0.607
2.032GluPro: 2.032 ± 0.516
1.693GluGln: 1.693 ± 0.386
2.709GluArg: 2.709 ± 0.601
4.29GluSer: 4.29 ± 0.64
3.048GluThr: 3.048 ± 0.539
2.371GluVal: 2.371 ± 0.442
1.242GluTrp: 1.242 ± 0.385
1.129GluTyr: 1.129 ± 0.29
0.0GluXaa: 0.0 ± 0.0
Phe
2.032PheAla: 2.032 ± 0.5
1.919PheCys: 1.919 ± 0.59
2.258PheAsp: 2.258 ± 0.528
1.919PheGlu: 1.919 ± 0.349
3.5PhePhe: 3.5 ± 0.615
1.693PheGly: 1.693 ± 0.499
1.693PheHis: 1.693 ± 0.436
4.177PheIle: 4.177 ± 0.773
2.597PheLys: 2.597 ± 0.603
5.532PheLeu: 5.532 ± 0.914
1.242PheMet: 1.242 ± 0.498
3.387PheAsn: 3.387 ± 0.512
2.935PhePro: 2.935 ± 0.719
2.597PheGln: 2.597 ± 0.512
2.484PheArg: 2.484 ± 0.675
3.838PheSer: 3.838 ± 0.47
2.484PheThr: 2.484 ± 0.657
3.274PheVal: 3.274 ± 0.497
0.903PheTrp: 0.903 ± 0.399
2.371PheTyr: 2.371 ± 0.419
0.0PheXaa: 0.0 ± 0.0
Gly
3.161GlyAla: 3.161 ± 0.668
1.016GlyCys: 1.016 ± 0.431
2.709GlyAsp: 2.709 ± 0.537
2.145GlyGlu: 2.145 ± 0.485
2.935GlyPhe: 2.935 ± 0.412
2.709GlyGly: 2.709 ± 0.561
1.355GlyHis: 1.355 ± 0.476
2.822GlyIle: 2.822 ± 0.433
3.951GlyLys: 3.951 ± 0.787
3.5GlyLeu: 3.5 ± 0.727
0.564GlyMet: 0.564 ± 0.251
3.725GlyAsn: 3.725 ± 0.91
1.919GlyPro: 1.919 ± 0.478
2.145GlyGln: 2.145 ± 0.603
2.597GlyArg: 2.597 ± 0.686
3.161GlySer: 3.161 ± 0.663
3.161GlyThr: 3.161 ± 0.599
2.822GlyVal: 2.822 ± 0.633
0.903GlyTrp: 0.903 ± 0.264
2.032GlyTyr: 2.032 ± 0.466
0.0GlyXaa: 0.0 ± 0.0
His
0.677HisAla: 0.677 ± 0.34
2.145HisCys: 2.145 ± 0.852
0.677HisAsp: 0.677 ± 0.329
0.677HisGlu: 0.677 ± 0.286
1.242HisPhe: 1.242 ± 0.393
1.242HisGly: 1.242 ± 0.54
0.452HisHis: 0.452 ± 0.193
1.355HisIle: 1.355 ± 0.409
0.677HisLys: 0.677 ± 0.244
2.145HisLeu: 2.145 ± 0.554
0.564HisMet: 0.564 ± 0.235
1.355HisAsn: 1.355 ± 0.385
1.355HisPro: 1.355 ± 0.369
0.452HisGln: 0.452 ± 0.322
1.58HisArg: 1.58 ± 0.346
2.032HisSer: 2.032 ± 0.474
1.242HisThr: 1.242 ± 0.243
1.58HisVal: 1.58 ± 0.389
0.113HisTrp: 0.113 ± 0.113
0.903HisTyr: 0.903 ± 0.365
0.0HisXaa: 0.0 ± 0.0
Ile
3.613IleAla: 3.613 ± 0.603
1.355IleCys: 1.355 ± 0.406
3.161IleAsp: 3.161 ± 0.646
3.5IleGlu: 3.5 ± 0.524
2.145IlePhe: 2.145 ± 0.664
3.048IleGly: 3.048 ± 0.608
1.129IleHis: 1.129 ± 0.244
2.597IleIle: 2.597 ± 0.457
4.629IleLys: 4.629 ± 0.786
6.322IleLeu: 6.322 ± 0.945
0.677IleMet: 0.677 ± 0.175
3.613IleAsn: 3.613 ± 0.556
4.177IlePro: 4.177 ± 0.703
2.709IleGln: 2.709 ± 0.626
2.709IleArg: 2.709 ± 0.807
4.403IleSer: 4.403 ± 0.747
3.838IleThr: 3.838 ± 0.721
3.387IleVal: 3.387 ± 0.604
0.452IleTrp: 0.452 ± 0.187
1.693IleTyr: 1.693 ± 0.442
0.0IleXaa: 0.0 ± 0.0
Lys
3.387LysAla: 3.387 ± 0.806
1.806LysCys: 1.806 ± 0.611
3.5LysAsp: 3.5 ± 0.675
2.822LysGlu: 2.822 ± 0.695
3.387LysPhe: 3.387 ± 0.642
2.484LysGly: 2.484 ± 0.395
1.806LysHis: 1.806 ± 0.556
4.064LysIle: 4.064 ± 0.922
5.193LysLys: 5.193 ± 1.259
7.225LysLeu: 7.225 ± 1.218
0.79LysMet: 0.79 ± 0.305
3.387LysAsn: 3.387 ± 0.721
3.274LysPro: 3.274 ± 0.903
3.5LysGln: 3.5 ± 0.762
3.838LysArg: 3.838 ± 0.812
3.613LysSer: 3.613 ± 0.869
4.403LysThr: 4.403 ± 0.69
2.032LysVal: 2.032 ± 0.5
1.355LysTrp: 1.355 ± 0.381
3.951LysTyr: 3.951 ± 0.571
0.0LysXaa: 0.0 ± 0.0
Leu
5.306LeuAla: 5.306 ± 0.71
1.693LeuCys: 1.693 ± 0.543
3.838LeuAsp: 3.838 ± 0.763
4.403LeuGlu: 4.403 ± 0.689
4.403LeuPhe: 4.403 ± 0.789
4.403LeuGly: 4.403 ± 0.783
2.597LeuHis: 2.597 ± 0.74
6.096LeuIle: 6.096 ± 1.035
8.354LeuLys: 8.354 ± 1.058
9.822LeuLeu: 9.822 ± 1.11
2.258LeuMet: 2.258 ± 0.426
6.322LeuAsn: 6.322 ± 0.73
5.645LeuPro: 5.645 ± 0.704
5.532LeuGln: 5.532 ± 0.718
4.967LeuArg: 4.967 ± 0.792
7.564LeuSer: 7.564 ± 1.21
8.467LeuThr: 8.467 ± 1.607
3.613LeuVal: 3.613 ± 0.628
1.355LeuTrp: 1.355 ± 0.507
4.177LeuTyr: 4.177 ± 0.613
0.0LeuXaa: 0.0 ± 0.0
Met
2.032MetAla: 2.032 ± 0.499
0.452MetCys: 0.452 ± 0.213
1.355MetAsp: 1.355 ± 0.354
1.693MetGlu: 1.693 ± 0.367
1.129MetPhe: 1.129 ± 0.427
0.903MetGly: 0.903 ± 0.322
0.226MetHis: 0.226 ± 0.175
1.016MetIle: 1.016 ± 0.369
1.468MetLys: 1.468 ± 0.451
2.258MetLeu: 2.258 ± 0.515
0.452MetMet: 0.452 ± 0.205
1.468MetAsn: 1.468 ± 0.488
1.129MetPro: 1.129 ± 0.461
0.903MetGln: 0.903 ± 0.292
0.79MetArg: 0.79 ± 0.277
1.016MetSer: 1.016 ± 0.303
1.242MetThr: 1.242 ± 0.287
0.339MetVal: 0.339 ± 0.182
0.339MetTrp: 0.339 ± 0.174
1.129MetTyr: 1.129 ± 0.375
0.0MetXaa: 0.0 ± 0.0
Asn
3.951AsnAla: 3.951 ± 0.752
1.693AsnCys: 1.693 ± 0.423
2.258AsnAsp: 2.258 ± 0.453
3.387AsnGlu: 3.387 ± 0.615
3.613AsnPhe: 3.613 ± 0.591
2.258AsnGly: 2.258 ± 0.547
1.58AsnHis: 1.58 ± 0.399
3.951AsnIle: 3.951 ± 0.782
2.484AsnLys: 2.484 ± 0.575
6.435AsnLeu: 6.435 ± 0.873
2.258AsnMet: 2.258 ± 0.61
3.951AsnAsn: 3.951 ± 0.637
3.387AsnPro: 3.387 ± 0.663
2.484AsnGln: 2.484 ± 0.62
2.935AsnArg: 2.935 ± 0.677
4.854AsnSer: 4.854 ± 1.077
4.629AsnThr: 4.629 ± 0.778
3.951AsnVal: 3.951 ± 0.742
0.564AsnTrp: 0.564 ± 0.33
2.822AsnTyr: 2.822 ± 0.634
0.0AsnXaa: 0.0 ± 0.0
Pro
1.919ProAla: 1.919 ± 0.503
0.79ProCys: 0.79 ± 0.397
2.935ProAsp: 2.935 ± 0.637
4.064ProGlu: 4.064 ± 0.583
4.629ProPhe: 4.629 ± 0.682
1.919ProGly: 1.919 ± 0.407
0.564ProHis: 0.564 ± 0.233
2.709ProIle: 2.709 ± 0.298
2.145ProLys: 2.145 ± 0.421
4.854ProLeu: 4.854 ± 0.868
1.806ProMet: 1.806 ± 0.446
3.387ProAsn: 3.387 ± 0.917
4.064ProPro: 4.064 ± 0.859
2.145ProGln: 2.145 ± 0.58
1.806ProArg: 1.806 ± 0.395
3.951ProSer: 3.951 ± 0.707
2.822ProThr: 2.822 ± 0.448
3.725ProVal: 3.725 ± 0.694
0.79ProTrp: 0.79 ± 0.281
2.145ProTyr: 2.145 ± 0.645
0.0ProXaa: 0.0 ± 0.0
Gln
2.484GlnAla: 2.484 ± 0.603
0.903GlnCys: 0.903 ± 0.454
1.468GlnAsp: 1.468 ± 0.462
2.145GlnGlu: 2.145 ± 0.616
1.242GlnPhe: 1.242 ± 0.485
2.145GlnGly: 2.145 ± 0.398
1.016GlnHis: 1.016 ± 0.332
3.274GlnIle: 3.274 ± 0.556
3.838GlnLys: 3.838 ± 0.532
4.967GlnLeu: 4.967 ± 0.536
1.016GlnMet: 1.016 ± 0.301
3.387GlnAsn: 3.387 ± 0.593
2.258GlnPro: 2.258 ± 0.517
2.145GlnGln: 2.145 ± 0.477
2.371GlnArg: 2.371 ± 0.543
2.935GlnSer: 2.935 ± 0.611
2.597GlnThr: 2.597 ± 0.509
2.032GlnVal: 2.032 ± 0.401
0.903GlnTrp: 0.903 ± 0.288
1.468GlnTyr: 1.468 ± 0.388
0.0GlnXaa: 0.0 ± 0.0
Arg
2.371ArgAla: 2.371 ± 0.629
0.903ArgCys: 0.903 ± 0.447
2.032ArgAsp: 2.032 ± 0.633
2.709ArgGlu: 2.709 ± 0.615
1.806ArgPhe: 1.806 ± 0.419
2.935ArgGly: 2.935 ± 0.461
0.677ArgHis: 0.677 ± 0.257
2.371ArgIle: 2.371 ± 0.445
2.935ArgLys: 2.935 ± 0.649
5.08ArgLeu: 5.08 ± 0.747
1.016ArgMet: 1.016 ± 0.335
3.161ArgAsn: 3.161 ± 0.559
2.484ArgPro: 2.484 ± 0.577
2.032ArgGln: 2.032 ± 0.521
4.064ArgArg: 4.064 ± 1.167
2.935ArgSer: 2.935 ± 0.688
2.822ArgThr: 2.822 ± 0.488
2.371ArgVal: 2.371 ± 0.534
0.903ArgTrp: 0.903 ± 0.242
1.468ArgTyr: 1.468 ± 0.393
0.0ArgXaa: 0.0 ± 0.0
Ser
3.951SerAla: 3.951 ± 0.877
1.468SerCys: 1.468 ± 0.511
3.161SerAsp: 3.161 ± 0.828
5.193SerGlu: 5.193 ± 0.684
3.838SerPhe: 3.838 ± 0.596
4.854SerGly: 4.854 ± 0.925
1.58SerHis: 1.58 ± 0.372
3.274SerIle: 3.274 ± 0.559
4.29SerLys: 4.29 ± 0.774
8.806SerLeu: 8.806 ± 1.238
1.129SerMet: 1.129 ± 0.348
4.29SerAsn: 4.29 ± 0.582
3.387SerPro: 3.387 ± 0.765
4.064SerGln: 4.064 ± 0.742
3.161SerArg: 3.161 ± 0.679
5.08SerSer: 5.08 ± 0.739
2.822SerThr: 2.822 ± 0.429
2.709SerVal: 2.709 ± 0.512
1.129SerTrp: 1.129 ± 0.434
3.387SerTyr: 3.387 ± 0.469
0.0SerXaa: 0.0 ± 0.0
Thr
4.29ThrAla: 4.29 ± 1.0
0.79ThrCys: 0.79 ± 0.307
3.274ThrAsp: 3.274 ± 0.625
3.048ThrGlu: 3.048 ± 0.528
3.5ThrPhe: 3.5 ± 0.561
3.5ThrGly: 3.5 ± 0.63
1.693ThrHis: 1.693 ± 0.441
2.371ThrIle: 2.371 ± 0.532
3.161ThrLys: 3.161 ± 0.585
5.758ThrLeu: 5.758 ± 0.83
1.016ThrMet: 1.016 ± 0.242
2.935ThrAsn: 2.935 ± 0.971
3.274ThrPro: 3.274 ± 0.525
2.822ThrGln: 2.822 ± 0.46
2.371ThrArg: 2.371 ± 0.442
3.951ThrSer: 3.951 ± 0.585
3.838ThrThr: 3.838 ± 0.651
4.854ThrVal: 4.854 ± 0.775
0.677ThrTrp: 0.677 ± 0.267
3.387ThrTyr: 3.387 ± 0.648
0.0ThrXaa: 0.0 ± 0.0
Val
1.806ValAla: 1.806 ± 0.562
0.79ValCys: 0.79 ± 0.355
2.597ValAsp: 2.597 ± 0.469
2.822ValGlu: 2.822 ± 0.469
2.258ValPhe: 2.258 ± 0.591
2.371ValGly: 2.371 ± 0.481
1.242ValHis: 1.242 ± 0.404
3.161ValIle: 3.161 ± 0.715
3.161ValLys: 3.161 ± 0.576
5.419ValLeu: 5.419 ± 0.701
0.226ValMet: 0.226 ± 0.144
2.822ValAsn: 2.822 ± 0.618
2.822ValPro: 2.822 ± 0.688
1.693ValGln: 1.693 ± 0.409
1.919ValArg: 1.919 ± 0.442
4.741ValSer: 4.741 ± 0.651
3.613ValThr: 3.613 ± 0.644
2.709ValVal: 2.709 ± 0.495
0.677ValTrp: 0.677 ± 0.277
2.822ValTyr: 2.822 ± 0.625
0.0ValXaa: 0.0 ± 0.0
Trp
0.79TrpAla: 0.79 ± 0.307
0.564TrpCys: 0.564 ± 0.32
0.677TrpAsp: 0.677 ± 0.197
0.903TrpGlu: 0.903 ± 0.523
0.564TrpPhe: 0.564 ± 0.247
1.129TrpGly: 1.129 ± 0.325
0.113TrpHis: 0.113 ± 0.138
0.452TrpIle: 0.452 ± 0.234
1.58TrpLys: 1.58 ± 0.662
1.242TrpLeu: 1.242 ± 0.473
0.339TrpMet: 0.339 ± 0.17
1.016TrpAsn: 1.016 ± 0.338
0.79TrpPro: 0.79 ± 0.348
0.79TrpGln: 0.79 ± 0.267
0.113TrpArg: 0.113 ± 0.107
1.016TrpSer: 1.016 ± 0.31
1.129TrpThr: 1.129 ± 0.313
0.226TrpVal: 0.226 ± 0.186
0.226TrpTrp: 0.226 ± 0.158
0.903TrpTyr: 0.903 ± 0.322
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.355TyrAla: 1.355 ± 0.373
1.129TyrCys: 1.129 ± 0.35
1.58TyrAsp: 1.58 ± 0.59
1.468TyrGlu: 1.468 ± 0.423
3.613TyrPhe: 3.613 ± 0.628
3.161TyrGly: 3.161 ± 0.717
1.242TyrHis: 1.242 ± 0.376
2.371TyrIle: 2.371 ± 0.545
1.58TyrLys: 1.58 ± 0.5
5.419TyrLeu: 5.419 ± 0.84
0.903TyrMet: 0.903 ± 0.382
3.5TyrAsn: 3.5 ± 0.645
2.032TyrPro: 2.032 ± 0.422
2.597TyrGln: 2.597 ± 0.653
1.242TyrArg: 1.242 ± 0.36
3.5TyrSer: 3.5 ± 0.767
2.032TyrThr: 2.032 ± 0.475
1.58TyrVal: 1.58 ± 0.479
0.79TyrTrp: 0.79 ± 0.421
1.693TyrTyr: 1.693 ± 0.365
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 30 proteins (8859 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski