Amino acid dipepetide frequency for Robbsia andropogonis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.368AlaAla: 16.368 ± 0.161	1.308AlaCys: 1.308 ± 0.036	6.557AlaAsp: 6.557 ± 0.081	5.562AlaGlu: 5.562 ± 0.075	4.405AlaPhe: 4.405 ± 0.056	9.509AlaGly: 9.509 ± 0.087	2.85AlaHis: 2.85 ± 0.05	6.047AlaIle: 6.047 ± 0.074	3.593AlaLys: 3.593 ± 0.059	14.291AlaLeu: 14.291 ± 0.131	3.499AlaMet: 3.499 ± 0.051	3.305AlaAsn: 3.305 ± 0.055	5.65AlaPro: 5.65 ± 0.074	4.845AlaGln: 4.845 ± 0.059	8.908AlaArg: 8.908 ± 0.095	7.757AlaSer: 7.757 ± 0.081	6.62AlaThr: 6.62 ± 0.068	8.698AlaVal: 8.698 ± 0.085	1.687AlaTrp: 1.687 ± 0.043	2.734AlaTyr: 2.734 ± 0.048	0.0AlaXaa: 0.0 ± 0.0
Cys	1.206CysAla: 1.206 ± 0.031	0.136CysCys: 0.136 ± 0.009	0.596CysAsp: 0.596 ± 0.021	0.474CysGlu: 0.474 ± 0.019	0.349CysPhe: 0.349 ± 0.015	0.963CysGly: 0.963 ± 0.026	0.268CysHis: 0.268 ± 0.012	0.448CysIle: 0.448 ± 0.018	0.232CysLys: 0.232 ± 0.013	0.881CysLeu: 0.881 ± 0.026	0.216CysMet: 0.216 ± 0.011	0.248CysAsn: 0.248 ± 0.012	0.424CysPro: 0.424 ± 0.018	0.245CysGln: 0.245 ± 0.014	0.622CysArg: 0.622 ± 0.02	0.534CysSer: 0.534 ± 0.02	0.49CysThr: 0.49 ± 0.018	0.745CysVal: 0.745 ± 0.025	0.133CysTrp: 0.133 ± 0.01	0.23CysTyr: 0.23 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	8.258AspAla: 8.258 ± 0.096	0.483AspCys: 0.483 ± 0.021	3.41AspAsp: 3.41 ± 0.05	3.034AspGlu: 3.034 ± 0.049	1.945AspPhe: 1.945 ± 0.034	4.958AspGly: 4.958 ± 0.069	1.228AspHis: 1.228 ± 0.034	2.975AspIle: 2.975 ± 0.045	1.659AspLys: 1.659 ± 0.034	5.158AspLeu: 5.158 ± 0.056	1.356AspMet: 1.356 ± 0.028	1.473AspAsn: 1.473 ± 0.041	3.009AspPro: 3.009 ± 0.043	1.718AspGln: 1.718 ± 0.036	3.596AspArg: 3.596 ± 0.048	2.508AspSer: 2.508 ± 0.045	3.13AspThr: 3.13 ± 0.048	4.579AspVal: 4.579 ± 0.05	0.917AspTrp: 0.917 ± 0.028	1.431AspTyr: 1.431 ± 0.032	0.0AspXaa: 0.0 ± 0.0
Glu	5.885GluAla: 5.885 ± 0.063	0.4GluCys: 0.4 ± 0.019	2.093GluAsp: 2.093 ± 0.042	2.14GluGlu: 2.14 ± 0.047	1.428GluPhe: 1.428 ± 0.032	3.244GluGly: 3.244 ± 0.057	1.261GluHis: 1.261 ± 0.035	2.694GluIle: 2.694 ± 0.047	1.878GluLys: 1.878 ± 0.041	4.236GluLeu: 4.236 ± 0.063	1.278GluMet: 1.278 ± 0.032	1.441GluAsn: 1.441 ± 0.032	2.044GluPro: 2.044 ± 0.038	2.291GluGln: 2.291 ± 0.039	4.104GluArg: 4.104 ± 0.062	2.637GluSer: 2.637 ± 0.041	2.895GluThr: 2.895 ± 0.049	3.241GluVal: 3.241 ± 0.05	0.742GluTrp: 0.742 ± 0.023	1.039GluTyr: 1.039 ± 0.026	0.0GluXaa: 0.0 ± 0.0
Phe	4.403PheAla: 4.403 ± 0.064	0.43PheCys: 0.43 ± 0.019	2.703PheAsp: 2.703 ± 0.042	1.805PheGlu: 1.805 ± 0.034	1.377PhePhe: 1.377 ± 0.038	3.474PheGly: 3.474 ± 0.06	0.813PheHis: 0.813 ± 0.025	1.639PheIle: 1.639 ± 0.033	1.057PheLys: 1.057 ± 0.029	3.03PheLeu: 3.03 ± 0.049	0.76PheMet: 0.76 ± 0.025	1.14PheAsn: 1.14 ± 0.031	1.554PhePro: 1.554 ± 0.033	1.125PheGln: 1.125 ± 0.026	1.975PheArg: 1.975 ± 0.036	2.446PheSer: 2.446 ± 0.047	1.984PheThr: 1.984 ± 0.041	2.85PheVal: 2.85 ± 0.046	0.471PheTrp: 0.471 ± 0.017	0.948PheTyr: 0.948 ± 0.026	0.0PheXaa: 0.0 ± 0.0
Gly	9.116GlyAla: 9.116 ± 0.088	0.808GlyCys: 0.808 ± 0.025	4.167GlyAsp: 4.167 ± 0.058	3.82GlyGlu: 3.82 ± 0.06	3.256GlyPhe: 3.256 ± 0.051	6.333GlyGly: 6.333 ± 0.085	1.875GlyHis: 1.875 ± 0.04	4.445GlyIle: 4.445 ± 0.059	3.069GlyLys: 3.069 ± 0.054	7.808GlyLeu: 7.808 ± 0.092	2.334GlyMet: 2.334 ± 0.04	2.489GlyAsn: 2.489 ± 0.05	2.907GlyPro: 2.907 ± 0.047	2.783GlyGln: 2.783 ± 0.05	5.203GlyArg: 5.203 ± 0.069	4.528GlySer: 4.528 ± 0.057	4.767GlyThr: 4.767 ± 0.07	6.512GlyVal: 6.512 ± 0.075	1.367GlyTrp: 1.367 ± 0.031	2.315GlyTyr: 2.315 ± 0.044	0.0GlyXaa: 0.0 ± 0.0
His	3.349HisAla: 3.349 ± 0.052	0.281HisCys: 0.281 ± 0.017	1.465HisAsp: 1.465 ± 0.035	1.059HisGlu: 1.059 ± 0.028	1.007HisPhe: 1.007 ± 0.027	2.193HisGly: 2.193 ± 0.042	0.707HisHis: 0.707 ± 0.026	1.062HisIle: 1.062 ± 0.03	0.481HisLys: 0.481 ± 0.02	2.235HisLeu: 2.235 ± 0.043	0.528HisMet: 0.528 ± 0.021	0.526HisAsn: 0.526 ± 0.02	1.536HisPro: 1.536 ± 0.034	0.77HisGln: 0.77 ± 0.023	1.777HisArg: 1.777 ± 0.039	1.082HisSer: 1.082 ± 0.029	1.165HisThr: 1.165 ± 0.029	1.79HisVal: 1.79 ± 0.034	0.436HisTrp: 0.436 ± 0.018	0.737HisTyr: 0.737 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	7.162IleAla: 7.162 ± 0.073	0.51IleCys: 0.51 ± 0.019	3.85IleAsp: 3.85 ± 0.058	2.949IleGlu: 2.949 ± 0.044	1.505IlePhe: 1.505 ± 0.035	4.946IleGly: 4.946 ± 0.063	0.955IleHis: 0.955 ± 0.024	1.974IleIle: 1.974 ± 0.042	1.456IleLys: 1.456 ± 0.036	3.901IleLeu: 3.901 ± 0.061	0.848IleMet: 0.848 ± 0.024	1.531IleAsn: 1.531 ± 0.037	2.282IlePro: 2.282 ± 0.04	1.402IleGln: 1.402 ± 0.031	3.017IleArg: 3.017 ± 0.051	2.885IleSer: 2.885 ± 0.047	2.782IleThr: 2.782 ± 0.045	4.419IleVal: 4.419 ± 0.056	0.545IleTrp: 0.545 ± 0.018	1.046IleTyr: 1.046 ± 0.027	0.0IleXaa: 0.0 ± 0.0
Lys	3.514LysAla: 3.514 ± 0.066	0.175LysCys: 0.175 ± 0.012	1.441LysAsp: 1.441 ± 0.035	1.354LysGlu: 1.354 ± 0.039	0.802LysPhe: 0.802 ± 0.023	2.128LysGly: 2.128 ± 0.039	0.73LysHis: 0.73 ± 0.023	1.649LysIle: 1.649 ± 0.031	1.177LysLys: 1.177 ± 0.04	3.03LysLeu: 3.03 ± 0.045	0.836LysMet: 0.836 ± 0.026	0.869LysAsn: 0.869 ± 0.028	1.717LysPro: 1.717 ± 0.035	1.341LysGln: 1.341 ± 0.031	2.385LysArg: 2.385 ± 0.048	1.805LysSer: 1.805 ± 0.039	1.966LysThr: 1.966 ± 0.042	2.236LysVal: 2.236 ± 0.044	0.381LysTrp: 0.381 ± 0.019	0.734LysTyr: 0.734 ± 0.023	0.0LysXaa: 0.0 ± 0.0
Leu	12.874LeuAla: 12.874 ± 0.126	1.058LeuCys: 1.058 ± 0.028	5.96LeuAsp: 5.96 ± 0.06	4.484LeuGlu: 4.484 ± 0.059	3.557LeuPhe: 3.557 ± 0.06	7.661LeuGly: 7.661 ± 0.087	2.493LeuHis: 2.493 ± 0.043	4.878LeuIle: 4.878 ± 0.077	3.096LeuLys: 3.096 ± 0.053	10.29LeuLeu: 10.29 ± 0.128	2.394LeuMet: 2.394 ± 0.046	2.679LeuAsn: 2.679 ± 0.041	5.934LeuPro: 5.934 ± 0.078	3.563LeuGln: 3.563 ± 0.057	7.362LeuArg: 7.362 ± 0.08	7.043LeuSer: 7.043 ± 0.063	5.794LeuThr: 5.794 ± 0.07	6.837LeuVal: 6.837 ± 0.075	1.117LeuTrp: 1.117 ± 0.029	2.144LeuTyr: 2.144 ± 0.041	0.0LeuXaa: 0.0 ± 0.0
Met	2.839MetAla: 2.839 ± 0.044	0.173MetCys: 0.173 ± 0.01	1.072MetAsp: 1.072 ± 0.027	0.875MetGlu: 0.875 ± 0.024	0.766MetPhe: 0.766 ± 0.024	1.631MetGly: 1.631 ± 0.039	0.685MetHis: 0.685 ± 0.019	1.218MetIle: 1.218 ± 0.033	0.891MetLys: 0.891 ± 0.026	2.841MetLeu: 2.841 ± 0.048	0.657MetMet: 0.657 ± 0.025	0.839MetAsn: 0.839 ± 0.023	1.678MetPro: 1.678 ± 0.035	1.144MetGln: 1.144 ± 0.027	2.011MetArg: 2.011 ± 0.039	1.813MetSer: 1.813 ± 0.036	1.73MetThr: 1.73 ± 0.035	1.711MetVal: 1.711 ± 0.034	0.213MetTrp: 0.213 ± 0.012	0.439MetTyr: 0.439 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	3.937AsnAla: 3.937 ± 0.058	0.239AsnCys: 0.239 ± 0.013	1.625AsnAsp: 1.625 ± 0.037	1.23AsnGlu: 1.23 ± 0.033	0.941AsnPhe: 0.941 ± 0.026	2.684AsnGly: 2.684 ± 0.048	0.598AsnHis: 0.598 ± 0.021	1.327AsnIle: 1.327 ± 0.034	0.783AsnLys: 0.783 ± 0.028	2.641AsnLeu: 2.641 ± 0.045	0.616AsnMet: 0.616 ± 0.02	0.9AsnAsn: 0.9 ± 0.03	1.679AsnPro: 1.679 ± 0.031	0.991AsnGln: 0.991 ± 0.025	1.785AsnArg: 1.785 ± 0.035	1.341AsnSer: 1.341 ± 0.035	1.63AsnThr: 1.63 ± 0.036	2.382AsnVal: 2.382 ± 0.04	0.431AsnTrp: 0.431 ± 0.02	0.694AsnTyr: 0.694 ± 0.027	0.0AsnXaa: 0.0 ± 0.0
Pro	5.923ProAla: 5.923 ± 0.072	0.337ProCys: 0.337 ± 0.016	3.303ProAsp: 3.303 ± 0.05	2.78ProGlu: 2.78 ± 0.043	1.879ProPhe: 1.879 ± 0.036	4.113ProGly: 4.113 ± 0.052	1.304ProHis: 1.304 ± 0.031	2.364ProIle: 2.364 ± 0.033	1.364ProLys: 1.364 ± 0.031	5.074ProLeu: 5.074 ± 0.069	1.258ProMet: 1.258 ± 0.03	1.451ProAsn: 1.451 ± 0.031	2.525ProPro: 2.525 ± 0.051	1.658ProGln: 1.658 ± 0.038	2.97ProArg: 2.97 ± 0.055	3.28ProSer: 3.28 ± 0.047	2.886ProThr: 2.886 ± 0.044	4.148ProVal: 4.148 ± 0.053	0.649ProTrp: 0.649 ± 0.022	1.244ProTyr: 1.244 ± 0.029	0.0ProXaa: 0.0 ± 0.0
Gln	4.795GlnAla: 4.795 ± 0.072	0.33GlnCys: 0.33 ± 0.016	1.545GlnAsp: 1.545 ± 0.036	1.32GlnGlu: 1.32 ± 0.03	1.234GlnPhe: 1.234 ± 0.028	2.595GlnGly: 2.595 ± 0.05	0.957GlnHis: 0.957 ± 0.027	1.942GlnIle: 1.942 ± 0.042	1.082GlnLys: 1.082 ± 0.027	3.556GlnLeu: 3.556 ± 0.051	1.008GlnMet: 1.008 ± 0.026	0.993GlnAsn: 0.993 ± 0.025	1.842GlnPro: 1.842 ± 0.037	1.779GlnGln: 1.779 ± 0.041	3.107GlnArg: 3.107 ± 0.042	2.235GlnSer: 2.235 ± 0.037	2.076GlnThr: 2.076 ± 0.042	2.552GlnVal: 2.552 ± 0.046	0.636GlnTrp: 0.636 ± 0.019	0.947GlnTyr: 0.947 ± 0.023	0.0GlnXaa: 0.0 ± 0.0
Arg	7.922ArgAla: 7.922 ± 0.096	0.68ArgCys: 0.68 ± 0.021	4.332ArgAsp: 4.332 ± 0.063	3.818ArgGlu: 3.818 ± 0.058	2.953ArgPhe: 2.953 ± 0.044	4.738ArgGly: 4.738 ± 0.073	2.046ArgHis: 2.046 ± 0.037	3.831ArgIle: 3.831 ± 0.052	2.028ArgLys: 2.028 ± 0.036	7.257ArgLeu: 7.257 ± 0.095	1.883ArgMet: 1.883 ± 0.036	2.021ArgAsn: 2.021 ± 0.038	3.069ArgPro: 3.069 ± 0.046	2.828ArgGln: 2.828 ± 0.05	5.372ArgArg: 5.372 ± 0.079	3.553ArgSer: 3.553 ± 0.055	3.646ArgThr: 3.646 ± 0.052	5.042ArgVal: 5.042 ± 0.066	1.137ArgTrp: 1.137 ± 0.029	2.091ArgTyr: 2.091 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	7.219SerAla: 7.219 ± 0.087	0.454SerCys: 0.454 ± 0.016	3.344SerAsp: 3.344 ± 0.052	2.646SerGlu: 2.646 ± 0.045	2.098SerPhe: 2.098 ± 0.04	5.524SerGly: 5.524 ± 0.075	1.344SerHis: 1.344 ± 0.028	3.028SerIle: 3.028 ± 0.039	1.715SerLys: 1.715 ± 0.036	5.881SerLeu: 5.881 ± 0.073	1.544SerMet: 1.544 ± 0.034	1.9SerAsn: 1.9 ± 0.04	3.006SerPro: 3.006 ± 0.049	1.88SerGln: 1.88 ± 0.04	4.073SerArg: 4.073 ± 0.052	3.661SerSer: 3.661 ± 0.073	3.525SerThr: 3.525 ± 0.066	4.569SerVal: 4.569 ± 0.06	0.797SerTrp: 0.797 ± 0.025	1.388SerTyr: 1.388 ± 0.036	0.0SerXaa: 0.0 ± 0.0
Thr	6.43ThrAla: 6.43 ± 0.073	0.426ThrCys: 0.426 ± 0.019	2.932ThrAsp: 2.932 ± 0.042	2.358ThrGlu: 2.358 ± 0.036	2.092ThrPhe: 2.092 ± 0.038	4.69ThrGly: 4.69 ± 0.067	1.448ThrHis: 1.448 ± 0.034	2.799ThrIle: 2.799 ± 0.044	1.318ThrLys: 1.318 ± 0.035	6.935ThrLeu: 6.935 ± 0.076	1.373ThrMet: 1.373 ± 0.031	1.435ThrAsn: 1.435 ± 0.04	3.732ThrPro: 3.732 ± 0.051	2.047ThrGln: 2.047 ± 0.038	3.599ThrArg: 3.599 ± 0.05	3.44ThrSer: 3.44 ± 0.059	3.281ThrThr: 3.281 ± 0.063	4.673ThrVal: 4.673 ± 0.061	0.692ThrTrp: 0.692 ± 0.022	1.261ThrTyr: 1.261 ± 0.038	0.0ThrXaa: 0.0 ± 0.0
Val	9.054ValAla: 9.054 ± 0.079	0.791ValCys: 0.791 ± 0.022	4.405ValAsp: 4.405 ± 0.061	3.651ValGlu: 3.651 ± 0.057	2.786ValPhe: 2.786 ± 0.041	5.592ValGly: 5.592 ± 0.078	1.581ValHis: 1.581 ± 0.036	3.969ValIle: 3.969 ± 0.052	2.352ValLys: 2.352 ± 0.043	7.731ValLeu: 7.731 ± 0.076	1.998ValMet: 1.998 ± 0.041	2.11ValAsn: 2.11 ± 0.039	3.994ValPro: 3.994 ± 0.051	2.417ValGln: 2.417 ± 0.041	5.058ValArg: 5.058 ± 0.059	4.961ValSer: 4.961 ± 0.068	4.623ValThr: 4.623 ± 0.055	6.051ValVal: 6.051 ± 0.076	0.952ValTrp: 0.952 ± 0.029	1.575ValTyr: 1.575 ± 0.037	0.0ValXaa: 0.0 ± 0.0
Trp	1.15TrpAla: 1.15 ± 0.031	0.156TrpCys: 0.156 ± 0.011	0.596TrpAsp: 0.596 ± 0.023	0.517TrpGlu: 0.517 ± 0.02	0.566TrpPhe: 0.566 ± 0.021	0.815TrpGly: 0.815 ± 0.026	0.475TrpHis: 0.475 ± 0.018	0.755TrpIle: 0.755 ± 0.026	0.377TrpLys: 0.377 ± 0.017	1.872TrpLeu: 1.872 ± 0.039	0.383TrpMet: 0.383 ± 0.019	0.435TrpAsn: 0.435 ± 0.019	0.677TrpPro: 0.677 ± 0.022	0.753TrpGln: 0.753 ± 0.02	1.395TrpArg: 1.395 ± 0.034	0.834TrpSer: 0.834 ± 0.025	0.704TrpThr: 0.704 ± 0.022	0.908TrpVal: 0.908 ± 0.023	0.211TrpTrp: 0.211 ± 0.012	0.328TrpTyr: 0.328 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.788TyrAla: 2.788 ± 0.049	0.264TyrCys: 0.264 ± 0.012	1.431TyrAsp: 1.431 ± 0.036	1.095TyrGlu: 1.095 ± 0.027	1.04TyrPhe: 1.04 ± 0.026	2.109TyrGly: 2.109 ± 0.043	0.568TyrHis: 0.568 ± 0.02	0.922TyrIle: 0.922 ± 0.026	0.661TyrLys: 0.661 ± 0.024	2.569TyrLeu: 2.569 ± 0.047	0.456TyrMet: 0.456 ± 0.018	0.666TyrAsn: 0.666 ± 0.021	1.25TyrPro: 1.25 ± 0.03	0.953TyrGln: 0.953 ± 0.026	1.928TyrArg: 1.928 ± 0.041	1.255TyrSer: 1.255 ± 0.032	1.268TyrThr: 1.268 ± 0.035	1.71TyrVal: 1.71 ± 0.033	0.394TyrTrp: 0.394 ± 0.019	0.636TyrTyr: 0.636 ± 0.024	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4737 proteins (1470760 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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