Amino acid dipepetide frequency for Stemphylium lycopersici

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.337AlaAla: 9.337 ± 0.057	1.05AlaCys: 1.05 ± 0.017	4.414AlaAsp: 4.414 ± 0.026	5.413AlaGlu: 5.413 ± 0.045	3.225AlaPhe: 3.225 ± 0.025	5.88AlaGly: 5.88 ± 0.043	1.984AlaHis: 1.984 ± 0.018	4.271AlaIle: 4.271 ± 0.033	4.501AlaLys: 4.501 ± 0.035	7.671AlaLeu: 7.671 ± 0.045	2.112AlaMet: 2.112 ± 0.025	3.247AlaAsn: 3.247 ± 0.021	5.586AlaPro: 5.586 ± 0.045	3.77AlaGln: 3.77 ± 0.035	5.025AlaArg: 5.025 ± 0.037	7.71AlaSer: 7.71 ± 0.05	5.638AlaThr: 5.638 ± 0.034	5.278AlaVal: 5.278 ± 0.036	1.177AlaTrp: 1.177 ± 0.017	2.287AlaTyr: 2.287 ± 0.023	0.0AlaXaa: 0.0 ± 0.0
Cys	0.939CysAla: 0.939 ± 0.015	0.221CysCys: 0.221 ± 0.008	0.649CysAsp: 0.649 ± 0.013	0.602CysGlu: 0.602 ± 0.012	0.498CysPhe: 0.498 ± 0.011	0.885CysGly: 0.885 ± 0.016	0.293CysHis: 0.293 ± 0.008	0.657CysIle: 0.657 ± 0.013	0.494CysLys: 0.494 ± 0.011	1.093CysLeu: 1.093 ± 0.015	0.266CysMet: 0.266 ± 0.007	0.44CysAsn: 0.44 ± 0.01	0.63CysPro: 0.63 ± 0.013	0.403CysGln: 0.403 ± 0.01	0.636CysArg: 0.636 ± 0.012	0.826CysSer: 0.826 ± 0.015	0.695CysThr: 0.695 ± 0.013	0.756CysVal: 0.756 ± 0.012	0.19CysTrp: 0.19 ± 0.005	0.337CysTyr: 0.337 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	5.273AspAla: 5.273 ± 0.03	0.612AspCys: 0.612 ± 0.011	4.448AspAsp: 4.448 ± 0.044	4.585AspGlu: 4.585 ± 0.037	2.24AspPhe: 2.24 ± 0.02	3.991AspGly: 3.991 ± 0.031	1.209AspHis: 1.209 ± 0.017	2.913AspIle: 2.913 ± 0.024	2.452AspLys: 2.452 ± 0.027	4.756AspLeu: 4.756 ± 0.032	1.413AspMet: 1.413 ± 0.018	1.883AspAsn: 1.883 ± 0.019	3.244AspPro: 3.244 ± 0.027	1.883AspGln: 1.883 ± 0.02	2.978AspArg: 2.978 ± 0.029	3.965AspSer: 3.965 ± 0.031	3.109AspThr: 3.109 ± 0.025	3.789AspVal: 3.789 ± 0.03	0.913AspTrp: 0.913 ± 0.014	1.626AspTyr: 1.626 ± 0.02	0.0AspXaa: 0.0 ± 0.0
Glu	5.733GluAla: 5.733 ± 0.041	0.615GluCys: 0.615 ± 0.011	4.36GluAsp: 4.36 ± 0.036	5.714GluGlu: 5.714 ± 0.061	1.855GluPhe: 1.855 ± 0.021	3.9GluGly: 3.9 ± 0.032	1.504GluHis: 1.504 ± 0.018	2.882GluIle: 2.882 ± 0.024	3.961GluLys: 3.961 ± 0.041	5.044GluLeu: 5.044 ± 0.039	1.497GluMet: 1.497 ± 0.014	2.254GluAsn: 2.254 ± 0.022	2.921GluPro: 2.921 ± 0.046	2.719GluGln: 2.719 ± 0.029	4.068GluArg: 4.068 ± 0.037	4.131GluSer: 4.131 ± 0.034	3.425GluThr: 3.425 ± 0.028	3.497GluVal: 3.497 ± 0.03	0.919GluTrp: 0.919 ± 0.016	1.708GluTyr: 1.708 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	3.191PheAla: 3.191 ± 0.029	0.512PheCys: 0.512 ± 0.01	2.302PheAsp: 2.302 ± 0.022	2.134PheGlu: 2.134 ± 0.022	1.574PhePhe: 1.574 ± 0.019	2.873PheGly: 2.873 ± 0.029	0.859PheHis: 0.859 ± 0.014	1.673PheIle: 1.673 ± 0.02	1.533PheLys: 1.533 ± 0.017	3.241PheLeu: 3.241 ± 0.026	0.777PheMet: 0.777 ± 0.012	1.457PheAsn: 1.457 ± 0.015	1.898PhePro: 1.898 ± 0.02	1.369PheGln: 1.369 ± 0.015	1.851PheArg: 1.851 ± 0.021	2.932PheSer: 2.932 ± 0.026	2.179PheThr: 2.179 ± 0.022	2.298PheVal: 2.298 ± 0.021	0.618PheTrp: 0.618 ± 0.011	1.052PheTyr: 1.052 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	5.576GlyAla: 5.576 ± 0.043	0.845GlyCys: 0.845 ± 0.014	3.617GlyAsp: 3.617 ± 0.027	3.774GlyGlu: 3.774 ± 0.032	2.779GlyPhe: 2.779 ± 0.026	6.059GlyGly: 6.059 ± 0.063	1.675GlyHis: 1.675 ± 0.023	3.374GlyIle: 3.374 ± 0.031	3.617GlyLys: 3.617 ± 0.034	5.738GlyLeu: 5.738 ± 0.04	1.699GlyMet: 1.699 ± 0.021	2.576GlyAsn: 2.576 ± 0.025	3.281GlyPro: 3.281 ± 0.029	2.559GlyGln: 2.559 ± 0.025	4.022GlyArg: 4.022 ± 0.033	5.483GlySer: 5.483 ± 0.036	3.927GlyThr: 3.927 ± 0.027	4.276GlyVal: 4.276 ± 0.034	1.163GlyTrp: 1.163 ± 0.018	2.176GlyTyr: 2.176 ± 0.025	0.0GlyXaa: 0.0 ± 0.0
His	2.049HisAla: 2.049 ± 0.022	0.314HisCys: 0.314 ± 0.009	1.372HisAsp: 1.372 ± 0.015	1.395HisGlu: 1.395 ± 0.016	0.928HisPhe: 0.928 ± 0.013	1.703HisGly: 1.703 ± 0.021	0.898HisHis: 0.898 ± 0.019	1.213HisIle: 1.213 ± 0.015	0.969HisLys: 0.969 ± 0.013	2.186HisLeu: 2.186 ± 0.02	0.541HisMet: 0.541 ± 0.01	0.884HisAsn: 0.884 ± 0.013	1.665HisPro: 1.665 ± 0.018	1.037HisGln: 1.037 ± 0.017	1.485HisArg: 1.485 ± 0.019	1.878HisSer: 1.878 ± 0.02	1.387HisThr: 1.387 ± 0.018	1.505HisVal: 1.505 ± 0.016	0.344HisTrp: 0.344 ± 0.008	0.723HisTyr: 0.723 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	4.339IleAla: 4.339 ± 0.032	0.677IleCys: 0.677 ± 0.012	2.806IleAsp: 2.806 ± 0.023	2.849IleGlu: 2.849 ± 0.027	1.854IlePhe: 1.854 ± 0.022	3.081IleGly: 3.081 ± 0.029	1.146IleHis: 1.146 ± 0.016	2.314IleIle: 2.314 ± 0.023	2.216IleLys: 2.216 ± 0.023	4.145IleLeu: 4.145 ± 0.031	1.005IleMet: 1.005 ± 0.016	1.755IleAsn: 1.755 ± 0.02	2.977IlePro: 2.977 ± 0.025	1.839IleGln: 1.839 ± 0.018	2.566IleArg: 2.566 ± 0.024	3.63IleSer: 3.63 ± 0.03	2.865IleThr: 2.865 ± 0.026	3.053IleVal: 3.053 ± 0.029	0.693IleTrp: 0.693 ± 0.013	1.349IleTyr: 1.349 ± 0.018	0.0IleXaa: 0.0 ± 0.0
Lys	4.6LysAla: 4.6 ± 0.034	0.49LysCys: 0.49 ± 0.011	3.006LysAsp: 3.006 ± 0.03	3.681LysGlu: 3.681 ± 0.037	1.442LysPhe: 1.442 ± 0.017	3.147LysGly: 3.147 ± 0.029	1.21LysHis: 1.21 ± 0.018	2.244LysIle: 2.244 ± 0.021	3.762LysLys: 3.762 ± 0.049	4.045LysLeu: 4.045 ± 0.032	1.117LysMet: 1.117 ± 0.014	1.837LysAsn: 1.837 ± 0.02	2.956LysPro: 2.956 ± 0.033	2.028LysGln: 2.028 ± 0.022	3.599LysArg: 3.599 ± 0.028	3.544LysSer: 3.544 ± 0.035	2.981LysThr: 2.981 ± 0.025	2.755LysVal: 2.755 ± 0.026	0.694LysTrp: 0.694 ± 0.011	1.369LysTyr: 1.369 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	7.53LeuAla: 7.53 ± 0.042	1.09LeuCys: 1.09 ± 0.016	4.918LeuAsp: 4.918 ± 0.033	5.281LeuGlu: 5.281 ± 0.042	3.116LeuPhe: 3.116 ± 0.03	5.569LeuGly: 5.569 ± 0.042	2.196LeuHis: 2.196 ± 0.022	3.655LeuIle: 3.655 ± 0.032	4.149LeuLys: 4.149 ± 0.032	7.678LeuLeu: 7.678 ± 0.055	1.7LeuMet: 1.7 ± 0.019	3.1LeuAsn: 3.1 ± 0.023	5.457LeuPro: 5.457 ± 0.034	3.749LeuGln: 3.749 ± 0.03	5.423LeuArg: 5.423 ± 0.037	6.864LeuSer: 6.864 ± 0.041	4.609LeuThr: 4.609 ± 0.033	5.067LeuVal: 5.067 ± 0.034	1.133LeuTrp: 1.133 ± 0.018	2.258LeuTyr: 2.258 ± 0.021	0.0LeuXaa: 0.0 ± 0.0
Met	2.278MetAla: 2.278 ± 0.022	0.237MetCys: 0.237 ± 0.007	1.332MetAsp: 1.332 ± 0.018	1.305MetGlu: 1.305 ± 0.015	0.759MetPhe: 0.759 ± 0.012	1.557MetGly: 1.557 ± 0.02	0.52MetHis: 0.52 ± 0.01	0.946MetIle: 0.946 ± 0.013	1.061MetLys: 1.061 ± 0.013	1.87MetLeu: 1.87 ± 0.019	0.619MetMet: 0.619 ± 0.012	0.855MetAsn: 0.855 ± 0.013	1.412MetPro: 1.412 ± 0.019	0.974MetGln: 0.974 ± 0.014	1.346MetArg: 1.346 ± 0.014	1.951MetSer: 1.951 ± 0.022	1.349MetThr: 1.349 ± 0.016	1.306MetVal: 1.306 ± 0.017	0.271MetTrp: 0.271 ± 0.008	0.605MetTyr: 0.605 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.422AsnAla: 3.422 ± 0.026	0.415AsnCys: 0.415 ± 0.009	2.022AsnAsp: 2.022 ± 0.02	2.101AsnGlu: 2.101 ± 0.021	1.412AsnPhe: 1.412 ± 0.016	3.126AsnGly: 3.126 ± 0.026	0.857AsnHis: 0.857 ± 0.015	2.009AsnIle: 2.009 ± 0.02	1.674AsnLys: 1.674 ± 0.019	3.11AsnLeu: 3.11 ± 0.024	0.919AsnMet: 0.919 ± 0.013	1.583AsnAsn: 1.583 ± 0.023	2.441AsnPro: 2.441 ± 0.022	1.373AsnGln: 1.373 ± 0.018	1.917AsnArg: 1.917 ± 0.02	2.72AsnSer: 2.72 ± 0.024	2.357AsnThr: 2.357 ± 0.023	2.416AsnVal: 2.416 ± 0.022	0.575AsnTrp: 0.575 ± 0.01	1.059AsnTyr: 1.059 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	5.761ProAla: 5.761 ± 0.047	0.472ProCys: 0.472 ± 0.009	3.146ProAsp: 3.146 ± 0.025	3.902ProGlu: 3.902 ± 0.041	2.071ProPhe: 2.071 ± 0.022	3.815ProGly: 3.815 ± 0.033	1.467ProHis: 1.467 ± 0.018	2.608ProIle: 2.608 ± 0.025	2.897ProLys: 2.897 ± 0.028	4.628ProLeu: 4.628 ± 0.029	1.198ProMet: 1.198 ± 0.017	2.356ProAsn: 2.356 ± 0.025	5.649ProPro: 5.649 ± 0.088	2.749ProGln: 2.749 ± 0.034	3.468ProArg: 3.468 ± 0.034	6.196ProSer: 6.196 ± 0.056	4.392ProThr: 4.392 ± 0.034	3.55ProVal: 3.55 ± 0.029	0.72ProTrp: 0.72 ± 0.013	1.579ProTyr: 1.579 ± 0.021	0.0ProXaa: 0.0 ± 0.0
Gln	3.682GlnAla: 3.682 ± 0.03	0.443GlnCys: 0.443 ± 0.01	2.223GlnAsp: 2.223 ± 0.024	2.506GlnGlu: 2.506 ± 0.021	1.263GlnPhe: 1.263 ± 0.014	2.485GlnGly: 2.485 ± 0.026	1.244GlnHis: 1.244 ± 0.018	1.846GlnIle: 1.846 ± 0.019	2.116GlnLys: 2.116 ± 0.022	3.398GlnLeu: 3.398 ± 0.031	0.92GlnMet: 0.92 ± 0.015	1.628GlnAsn: 1.628 ± 0.02	2.785GlnPro: 2.785 ± 0.035	2.967GlnGln: 2.967 ± 0.062	2.736GlnArg: 2.736 ± 0.027	3.231GlnSer: 3.231 ± 0.033	2.368GlnThr: 2.368 ± 0.021	2.118GlnVal: 2.118 ± 0.019	0.577GlnTrp: 0.577 ± 0.011	1.251GlnTyr: 1.251 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	4.759ArgAla: 4.759 ± 0.032	0.638ArgCys: 0.638 ± 0.011	3.301ArgAsp: 3.301 ± 0.03	3.748ArgGlu: 3.748 ± 0.034	2.044ArgPhe: 2.044 ± 0.019	3.636ArgGly: 3.636 ± 0.036	1.536ArgHis: 1.536 ± 0.019	2.864ArgIle: 2.864 ± 0.022	3.598ArgLys: 3.598 ± 0.031	5.113ArgLeu: 5.113 ± 0.032	1.366ArgMet: 1.366 ± 0.015	2.373ArgAsn: 2.373 ± 0.023	3.566ArgPro: 3.566 ± 0.035	2.645ArgGln: 2.645 ± 0.028	4.884ArgArg: 4.884 ± 0.045	4.745ArgSer: 4.745 ± 0.048	3.319ArgThr: 3.319 ± 0.027	3.156ArgVal: 3.156 ± 0.023	0.877ArgTrp: 0.877 ± 0.014	1.617ArgTyr: 1.617 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	6.922SerAla: 6.922 ± 0.039	0.815SerCys: 0.815 ± 0.014	4.218SerAsp: 4.218 ± 0.028	4.182SerGlu: 4.182 ± 0.035	2.948SerPhe: 2.948 ± 0.026	5.399SerGly: 5.399 ± 0.04	2.008SerHis: 2.008 ± 0.022	3.815SerIle: 3.815 ± 0.03	3.808SerLys: 3.808 ± 0.035	6.672SerLeu: 6.672 ± 0.044	1.782SerMet: 1.782 ± 0.02	3.074SerAsn: 3.074 ± 0.024	5.711SerPro: 5.711 ± 0.057	3.287SerGln: 3.287 ± 0.031	4.83SerArg: 4.83 ± 0.04	8.493SerSer: 8.493 ± 0.076	5.697SerThr: 5.697 ± 0.044	4.388SerVal: 4.388 ± 0.029	1.058SerTrp: 1.058 ± 0.015	2.102SerTyr: 2.102 ± 0.021	0.0SerXaa: 0.0 ± 0.0
Thr	5.49ThrAla: 5.49 ± 0.034	0.746ThrCys: 0.746 ± 0.014	2.869ThrAsp: 2.869 ± 0.024	3.201ThrGlu: 3.201 ± 0.029	2.285ThrPhe: 2.285 ± 0.02	4.106ThrGly: 4.106 ± 0.03	1.366ThrHis: 1.366 ± 0.014	3.026ThrIle: 3.026 ± 0.024	2.785ThrLys: 2.785 ± 0.028	5.208ThrLeu: 5.208 ± 0.034	1.271ThrMet: 1.271 ± 0.015	2.217ThrAsn: 2.217 ± 0.02	4.76ThrPro: 4.76 ± 0.042	2.242ThrGln: 2.242 ± 0.023	3.152ThrArg: 3.152 ± 0.027	5.453ThrSer: 5.453 ± 0.037	4.453ThrThr: 4.453 ± 0.037	3.617ThrVal: 3.617 ± 0.028	0.847ThrTrp: 0.847 ± 0.013	1.639ThrTyr: 1.639 ± 0.018	0.0ThrXaa: 0.0 ± 0.0
Val	5.304ValAla: 5.304 ± 0.033	0.73ValCys: 0.73 ± 0.011	3.661ValAsp: 3.661 ± 0.027	3.881ValGlu: 3.881 ± 0.029	2.329ValPhe: 2.329 ± 0.022	3.983ValGly: 3.983 ± 0.033	1.394ValHis: 1.394 ± 0.019	2.751ValIle: 2.751 ± 0.023	2.947ValLys: 2.947 ± 0.028	5.19ValLeu: 5.19 ± 0.038	1.311ValMet: 1.311 ± 0.015	2.163ValAsn: 2.163 ± 0.021	3.524ValPro: 3.524 ± 0.028	2.463ValGln: 2.463 ± 0.02	3.311ValArg: 3.311 ± 0.024	4.381ValSer: 4.381 ± 0.034	3.405ValThr: 3.405 ± 0.029	4.127ValVal: 4.127 ± 0.036	0.85ValTrp: 0.85 ± 0.013	1.676ValTyr: 1.676 ± 0.02	0.0ValXaa: 0.0 ± 0.0
Trp	1.128TrpAla: 1.128 ± 0.017	0.196TrpCys: 0.196 ± 0.007	0.923TrpAsp: 0.923 ± 0.016	0.835TrpGlu: 0.835 ± 0.012	0.533TrpPhe: 0.533 ± 0.011	0.926TrpGly: 0.926 ± 0.015	0.359TrpHis: 0.359 ± 0.009	0.734TrpIle: 0.734 ± 0.012	0.812TrpLys: 0.812 ± 0.012	1.291TrpLeu: 1.291 ± 0.019	0.371TrpMet: 0.371 ± 0.009	0.641TrpAsn: 0.641 ± 0.01	0.601TrpPro: 0.601 ± 0.009	0.586TrpGln: 0.586 ± 0.011	0.905TrpArg: 0.905 ± 0.014	1.054TrpSer: 1.054 ± 0.016	0.89TrpThr: 0.89 ± 0.015	0.852TrpVal: 0.852 ± 0.014	0.267TrpTrp: 0.267 ± 0.007	0.434TrpTyr: 0.434 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.26TyrAla: 2.26 ± 0.019	0.396TyrCys: 0.396 ± 0.009	1.691TyrAsp: 1.691 ± 0.017	1.617TyrGlu: 1.617 ± 0.019	1.168TyrPhe: 1.168 ± 0.015	2.096TyrGly: 2.096 ± 0.025	0.752TyrHis: 0.752 ± 0.012	1.366TyrIle: 1.366 ± 0.016	1.159TyrLys: 1.159 ± 0.014	2.466TyrLeu: 2.466 ± 0.023	0.67TyrMet: 0.67 ± 0.012	1.185TyrAsn: 1.185 ± 0.017	1.559TyrPro: 1.559 ± 0.02	1.146TyrGln: 1.146 ± 0.015	1.582TyrArg: 1.582 ± 0.017	2.024TyrSer: 2.024 ± 0.023	1.686TyrThr: 1.686 ± 0.019	1.576TyrVal: 1.576 ± 0.019	0.451TyrTrp: 0.451 ± 0.009	0.934TyrTyr: 0.934 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 9079 proteins (5419111 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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