Amino acid dipepetide frequency for Arsenophonus endosymbiont of Bemisia tabaci Asia II 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.141AlaAla: 7.141 ± 0.159
0.951AlaCys: 0.951 ± 0.05
4.173AlaAsp: 4.173 ± 0.112
5.593AlaGlu: 5.593 ± 0.135
2.881AlaPhe: 2.881 ± 0.084
5.623AlaGly: 5.623 ± 0.148
1.508AlaHis: 1.508 ± 0.06
6.505AlaIle: 6.505 ± 0.135
5.495AlaLys: 5.495 ± 0.123
8.386AlaLeu: 8.386 ± 0.152
2.164AlaMet: 2.164 ± 0.079
3.778AlaAsn: 3.778 ± 0.122
2.508AlaPro: 2.508 ± 0.087
3.306AlaGln: 3.306 ± 0.103
3.891AlaArg: 3.891 ± 0.118
4.11AlaSer: 4.11 ± 0.11
4.259AlaThr: 4.259 ± 0.11
5.198AlaVal: 5.198 ± 0.12
0.796AlaTrp: 0.796 ± 0.039
2.253AlaTyr: 2.253 ± 0.082
0.0AlaXaa: 0.0 ± 0.0
Cys
0.732CysAla: 0.732 ± 0.038
0.231CysCys: 0.231 ± 0.026
0.671CysAsp: 0.671 ± 0.045
0.55CysGlu: 0.55 ± 0.038
0.54CysPhe: 0.54 ± 0.037
0.909CysGly: 0.909 ± 0.053
0.388CysHis: 0.388 ± 0.028
0.722CysIle: 0.722 ± 0.043
0.457CysLys: 0.457 ± 0.032
1.1CysLeu: 1.1 ± 0.045
0.243CysMet: 0.243 ± 0.026
0.359CysAsn: 0.359 ± 0.03
0.457CysPro: 0.457 ± 0.033
0.653CysGln: 0.653 ± 0.037
0.563CysArg: 0.563 ± 0.042
0.732CysSer: 0.732 ± 0.043
0.484CysThr: 0.484 ± 0.034
0.644CysVal: 0.644 ± 0.04
0.216CysTrp: 0.216 ± 0.025
0.474CysTyr: 0.474 ± 0.034
0.0CysXaa: 0.0 ± 0.0
Asp
3.697AspAla: 3.697 ± 0.087
0.609AspCys: 0.609 ± 0.036
2.795AspAsp: 2.795 ± 0.084
3.631AspGlu: 3.631 ± 0.095
2.27AspPhe: 2.27 ± 0.073
3.218AspGly: 3.218 ± 0.089
0.987AspHis: 0.987 ± 0.042
4.409AspIle: 4.409 ± 0.105
3.495AspLys: 3.495 ± 0.093
4.842AspLeu: 4.842 ± 0.124
1.373AspMet: 1.373 ± 0.059
2.712AspAsn: 2.712 ± 0.093
2.14AspPro: 2.14 ± 0.069
1.774AspGln: 1.774 ± 0.068
2.417AspArg: 2.417 ± 0.084
2.903AspSer: 2.903 ± 0.095
2.375AspThr: 2.375 ± 0.074
3.363AspVal: 3.363 ± 0.089
0.744AspTrp: 0.744 ± 0.047
2.027AspTyr: 2.027 ± 0.078
0.0AspXaa: 0.0 ± 0.0
Glu
4.429GluAla: 4.429 ± 0.126
0.521GluCys: 0.521 ± 0.037
2.353GluAsp: 2.353 ± 0.08
3.64GluGlu: 3.64 ± 0.104
2.034GluPhe: 2.034 ± 0.073
3.211GluGly: 3.211 ± 0.094
1.378GluHis: 1.378 ± 0.058
4.672GluIle: 4.672 ± 0.109
4.616GluLys: 4.616 ± 0.118
6.389GluLeu: 6.389 ± 0.13
1.71GluMet: 1.71 ± 0.069
2.958GluAsn: 2.958 ± 0.102
1.766GluPro: 1.766 ± 0.065
3.751GluGln: 3.751 ± 0.106
3.508GluArg: 3.508 ± 0.111
2.928GluSer: 2.928 ± 0.088
2.913GluThr: 2.913 ± 0.091
3.68GluVal: 3.68 ± 0.102
0.663GluTrp: 0.663 ± 0.044
1.692GluTyr: 1.692 ± 0.062
0.0GluXaa: 0.0 ± 0.0
Phe
3.122PheAla: 3.122 ± 0.083
0.592PheCys: 0.592 ± 0.04
2.373PheAsp: 2.373 ± 0.076
1.936PheGlu: 1.936 ± 0.067
1.719PhePhe: 1.719 ± 0.088
2.749PheGly: 2.749 ± 0.075
0.87PheHis: 0.87 ± 0.05
3.449PheIle: 3.449 ± 0.111
1.847PheLys: 1.847 ± 0.07
3.328PheLeu: 3.328 ± 0.104
1.019PheMet: 1.019 ± 0.049
2.218PheAsn: 2.218 ± 0.078
1.447PhePro: 1.447 ± 0.059
1.238PheGln: 1.238 ± 0.062
1.697PheArg: 1.697 ± 0.064
3.262PheSer: 3.262 ± 0.093
2.23PheThr: 2.23 ± 0.077
2.203PheVal: 2.203 ± 0.088
0.491PheTrp: 0.491 ± 0.035
1.427PheTyr: 1.427 ± 0.062
0.0PheXaa: 0.0 ± 0.0
Gly
4.665GlyAla: 4.665 ± 0.126
0.85GlyCys: 0.85 ± 0.046
3.279GlyAsp: 3.279 ± 0.087
3.854GlyGlu: 3.854 ± 0.116
2.864GlyPhe: 2.864 ± 0.097
4.436GlyGly: 4.436 ± 0.132
1.56GlyHis: 1.56 ± 0.065
5.249GlyIle: 5.249 ± 0.137
4.311GlyLys: 4.311 ± 0.117
6.323GlyLeu: 6.323 ± 0.142
1.825GlyMet: 1.825 ± 0.066
2.793GlyAsn: 2.793 ± 0.089
1.663GlyPro: 1.663 ± 0.068
2.847GlyGln: 2.847 ± 0.078
3.274GlyArg: 3.274 ± 0.09
3.643GlySer: 3.643 ± 0.098
3.117GlyThr: 3.117 ± 0.091
4.343GlyVal: 4.343 ± 0.111
0.946GlyTrp: 0.946 ± 0.047
2.366GlyTyr: 2.366 ± 0.077
0.0GlyXaa: 0.0 ± 0.0
His
1.67HisAla: 1.67 ± 0.065
0.359HisCys: 0.359 ± 0.033
1.059HisAsp: 1.059 ± 0.06
1.088HisGlu: 1.088 ± 0.047
1.073HisPhe: 1.073 ± 0.053
1.555HisGly: 1.555 ± 0.063
0.742HisHis: 0.742 ± 0.046
1.697HisIle: 1.697 ± 0.067
1.081HisLys: 1.081 ± 0.048
2.346HisLeu: 2.346 ± 0.077
0.538HisMet: 0.538 ± 0.036
1.042HisAsn: 1.042 ± 0.052
1.132HisPro: 1.132 ± 0.054
1.265HisGln: 1.265 ± 0.062
1.125HisArg: 1.125 ± 0.051
1.317HisSer: 1.317 ± 0.06
1.127HisThr: 1.127 ± 0.052
1.145HisVal: 1.145 ± 0.059
0.354HisTrp: 0.354 ± 0.029
0.943HisTyr: 0.943 ± 0.048
0.0HisXaa: 0.0 ± 0.0
Ile
6.915IleAla: 6.915 ± 0.144
0.936IleCys: 0.936 ± 0.05
4.621IleAsp: 4.621 ± 0.101
5.043IleGlu: 5.043 ± 0.11
2.913IlePhe: 2.913 ± 0.102
5.227IleGly: 5.227 ± 0.135
1.597IleHis: 1.597 ± 0.061
6.141IleIle: 6.141 ± 0.134
4.606IleLys: 4.606 ± 0.107
6.998IleLeu: 6.998 ± 0.149
1.756IleMet: 1.756 ± 0.073
4.382IleAsn: 4.382 ± 0.136
3.026IlePro: 3.026 ± 0.087
2.763IleGln: 2.763 ± 0.089
3.594IleArg: 3.594 ± 0.096
5.264IleSer: 5.264 ± 0.108
4.726IleThr: 4.726 ± 0.107
4.677IleVal: 4.677 ± 0.118
0.781IleTrp: 0.781 ± 0.041
2.314IleTyr: 2.314 ± 0.08
0.0IleXaa: 0.0 ± 0.0
Lys
4.655LysAla: 4.655 ± 0.13
0.41LysCys: 0.41 ± 0.033
2.707LysAsp: 2.707 ± 0.095
3.508LysGlu: 3.508 ± 0.099
1.887LysPhe: 1.887 ± 0.073
3.481LysGly: 3.481 ± 0.108
1.194LysHis: 1.194 ± 0.06
4.802LysIle: 4.802 ± 0.119
4.2LysLys: 4.2 ± 0.13
6.178LysLeu: 6.178 ± 0.12
1.717LysMet: 1.717 ± 0.065
3.115LysAsn: 3.115 ± 0.096
2.366LysPro: 2.366 ± 0.085
3.385LysGln: 3.385 ± 0.099
3.176LysArg: 3.176 ± 0.102
3.336LysSer: 3.336 ± 0.086
3.39LysThr: 3.39 ± 0.1
3.66LysVal: 3.66 ± 0.093
0.607LysTrp: 0.607 ± 0.036
1.771LysTyr: 1.771 ± 0.069
0.0LysXaa: 0.0 ± 0.0
Leu
9.632LeuAla: 9.632 ± 0.166
1.145LeuCys: 1.145 ± 0.056
5.367LeuAsp: 5.367 ± 0.124
5.49LeuGlu: 5.49 ± 0.131
4.07LeuPhe: 4.07 ± 0.128
6.05LeuGly: 6.05 ± 0.131
2.093LeuHis: 2.093 ± 0.079
7.617LeuIle: 7.617 ± 0.162
5.822LeuLys: 5.822 ± 0.141
11.027LeuLeu: 11.027 ± 0.227
2.587LeuMet: 2.587 ± 0.074
4.935LeuAsn: 4.935 ± 0.103
4.982LeuPro: 4.982 ± 0.102
4.2LeuGln: 4.2 ± 0.117
5.188LeuArg: 5.188 ± 0.114
7.165LeuSer: 7.165 ± 0.155
6.436LeuThr: 6.436 ± 0.132
6.234LeuVal: 6.234 ± 0.134
1.132LeuTrp: 1.132 ± 0.057
2.894LeuTyr: 2.894 ± 0.087
0.0LeuXaa: 0.0 ± 0.0
Met
2.329MetAla: 2.329 ± 0.066
0.187MetCys: 0.187 ± 0.02
1.184MetAsp: 1.184 ± 0.052
1.27MetGlu: 1.27 ± 0.071
0.722MetPhe: 0.722 ± 0.044
1.648MetGly: 1.648 ± 0.062
0.516MetHis: 0.516 ± 0.038
1.84MetIle: 1.84 ± 0.077
1.602MetLys: 1.602 ± 0.067
2.901MetLeu: 2.901 ± 0.094
0.737MetMet: 0.737 ± 0.046
1.184MetAsn: 1.184 ± 0.053
1.277MetPro: 1.277 ± 0.056
1.221MetGln: 1.221 ± 0.058
1.42MetArg: 1.42 ± 0.054
1.678MetSer: 1.678 ± 0.062
1.432MetThr: 1.432 ± 0.062
1.651MetVal: 1.651 ± 0.069
0.189MetTrp: 0.189 ± 0.023
0.511MetTyr: 0.511 ± 0.033
0.0MetXaa: 0.0 ± 0.0
Asn
3.279AsnAla: 3.279 ± 0.096
0.464AsnCys: 0.464 ± 0.038
2.545AsnAsp: 2.545 ± 0.079
2.646AsnGlu: 2.646 ± 0.077
1.847AsnPhe: 1.847 ± 0.071
3.061AsnGly: 3.061 ± 0.101
1.108AsnHis: 1.108 ± 0.054
4.267AsnIle: 4.267 ± 0.126
3.095AsnLys: 3.095 ± 0.092
4.495AsnLeu: 4.495 ± 0.131
1.196AsnMet: 1.196 ± 0.05
3.088AsnAsn: 3.088 ± 0.101
2.051AsnPro: 2.051 ± 0.062
2.449AsnGln: 2.449 ± 0.08
2.267AsnArg: 2.267 ± 0.077
2.926AsnSer: 2.926 ± 0.089
2.339AsnThr: 2.339 ± 0.084
2.609AsnVal: 2.609 ± 0.078
0.73AsnTrp: 0.73 ± 0.045
1.781AsnTyr: 1.781 ± 0.065
0.0AsnXaa: 0.0 ± 0.0
Pro
3.338ProAla: 3.338 ± 0.115
0.339ProCys: 0.339 ± 0.029
2.37ProAsp: 2.37 ± 0.066
2.732ProGlu: 2.732 ± 0.081
1.602ProPhe: 1.602 ± 0.065
2.331ProGly: 2.331 ± 0.072
0.882ProHis: 0.882 ± 0.044
3.041ProIle: 3.041 ± 0.1
1.968ProLys: 1.968 ± 0.075
4.134ProLeu: 4.134 ± 0.112
0.951ProMet: 0.951 ± 0.048
1.786ProAsn: 1.786 ± 0.064
1.349ProPro: 1.349 ± 0.092
1.675ProGln: 1.675 ± 0.067
1.444ProArg: 1.444 ± 0.066
2.307ProSer: 2.307 ± 0.092
2.299ProThr: 2.299 ± 0.074
2.719ProVal: 2.719 ± 0.088
0.474ProTrp: 0.474 ± 0.039
1.263ProTyr: 1.263 ± 0.067
0.0ProXaa: 0.0 ± 0.0
Gln
3.916GlnAla: 3.916 ± 0.118
0.45GlnCys: 0.45 ± 0.035
1.855GlnAsp: 1.855 ± 0.069
2.233GlnGlu: 2.233 ± 0.071
1.882GlnPhe: 1.882 ± 0.076
2.675GlnGly: 2.675 ± 0.078
1.29GlnHis: 1.29 ± 0.065
3.464GlnIle: 3.464 ± 0.107
2.68GlnLys: 2.68 ± 0.084
5.787GlnLeu: 5.787 ± 0.134
1.091GlnMet: 1.091 ± 0.06
2.004GlnAsn: 2.004 ± 0.073
1.896GlnPro: 1.896 ± 0.074
3.741GlnGln: 3.741 ± 0.143
2.673GlnArg: 2.673 ± 0.084
2.614GlnSer: 2.614 ± 0.078
2.179GlnThr: 2.179 ± 0.079
2.894GlnVal: 2.894 ± 0.094
0.614GlnTrp: 0.614 ± 0.044
1.548GlnTyr: 1.548 ± 0.062
0.0GlnXaa: 0.0 ± 0.0
Arg
3.687ArgAla: 3.687 ± 0.104
0.533ArgCys: 0.533 ± 0.035
2.545ArgAsp: 2.545 ± 0.091
3.181ArgGlu: 3.181 ± 0.093
2.255ArgPhe: 2.255 ± 0.078
2.84ArgGly: 2.84 ± 0.09
1.353ArgHis: 1.353 ± 0.065
3.837ArgIle: 3.837 ± 0.102
2.845ArgLys: 2.845 ± 0.095
5.583ArgLeu: 5.583 ± 0.123
1.24ArgMet: 1.24 ± 0.052
2.105ArgAsn: 2.105 ± 0.077
1.887ArgPro: 1.887 ± 0.063
2.96ArgGln: 2.96 ± 0.1
3.066ArgArg: 3.066 ± 0.102
2.695ArgSer: 2.695 ± 0.083
2.198ArgThr: 2.198 ± 0.076
2.948ArgVal: 2.948 ± 0.087
0.695ArgTrp: 0.695 ± 0.048
1.97ArgTyr: 1.97 ± 0.074
0.0ArgXaa: 0.0 ± 0.0
Ser
4.689SerAla: 4.689 ± 0.112
0.658SerCys: 0.658 ± 0.044
3.238SerAsp: 3.238 ± 0.103
3.311SerGlu: 3.311 ± 0.092
2.486SerPhe: 2.486 ± 0.076
4.397SerGly: 4.397 ± 0.096
1.567SerHis: 1.567 ± 0.05
4.277SerIle: 4.277 ± 0.116
3.004SerLys: 3.004 ± 0.099
6.637SerLeu: 6.637 ± 0.129
1.459SerMet: 1.459 ± 0.056
2.712SerAsn: 2.712 ± 0.095
2.393SerPro: 2.393 ± 0.096
2.918SerGln: 2.918 ± 0.088
2.967SerArg: 2.967 ± 0.08
4.087SerSer: 4.087 ± 0.135
3.053SerThr: 3.053 ± 0.093
3.925SerVal: 3.925 ± 0.101
0.816SerTrp: 0.816 ± 0.056
1.906SerTyr: 1.906 ± 0.074
0.0SerXaa: 0.0 ± 0.0
Thr
4.311ThrAla: 4.311 ± 0.11
0.513ThrCys: 0.513 ± 0.036
2.889ThrAsp: 2.889 ± 0.09
3.277ThrGlu: 3.277 ± 0.098
1.882ThrPhe: 1.882 ± 0.069
3.911ThrGly: 3.911 ± 0.102
1.15ThrHis: 1.15 ± 0.046
4.161ThrIle: 4.161 ± 0.105
2.763ThrLys: 2.763 ± 0.092
6.075ThrLeu: 6.075 ± 0.12
1.211ThrMet: 1.211 ± 0.056
2.257ThrAsn: 2.257 ± 0.084
2.601ThrPro: 2.601 ± 0.081
2.186ThrGln: 2.186 ± 0.081
2.412ThrArg: 2.412 ± 0.078
2.967ThrSer: 2.967 ± 0.083
3.019ThrThr: 3.019 ± 0.085
3.427ThrVal: 3.427 ± 0.103
0.526ThrTrp: 0.526 ± 0.032
1.464ThrTyr: 1.464 ± 0.067
0.0ThrXaa: 0.0 ± 0.0
Val
5.345ValAla: 5.345 ± 0.14
0.644ValCys: 0.644 ± 0.048
3.552ValAsp: 3.552 ± 0.099
3.881ValGlu: 3.881 ± 0.109
2.326ValPhe: 2.326 ± 0.082
4.159ValGly: 4.159 ± 0.11
1.11ValHis: 1.11 ± 0.047
5.198ValIle: 5.198 ± 0.128
3.763ValLys: 3.763 ± 0.107
5.895ValLeu: 5.895 ± 0.126
1.724ValMet: 1.724 ± 0.068
2.948ValAsn: 2.948 ± 0.098
2.28ValPro: 2.28 ± 0.073
1.928ValGln: 1.928 ± 0.072
3.073ValArg: 3.073 ± 0.099
3.989ValSer: 3.989 ± 0.109
3.606ValThr: 3.606 ± 0.103
4.237ValVal: 4.237 ± 0.098
0.653ValTrp: 0.653 ± 0.044
1.572ValTyr: 1.572 ± 0.065
0.0ValXaa: 0.0 ± 0.0
Trp
0.685TrpAla: 0.685 ± 0.04
0.209TrpCys: 0.209 ± 0.024
0.477TrpAsp: 0.477 ± 0.032
0.45TrpGlu: 0.45 ± 0.028
0.531TrpPhe: 0.531 ± 0.03
0.626TrpGly: 0.626 ± 0.038
0.391TrpHis: 0.391 ± 0.027
0.808TrpIle: 0.808 ± 0.04
0.533TrpLys: 0.533 ± 0.041
1.963TrpLeu: 1.963 ± 0.084
0.319TrpMet: 0.319 ± 0.03
0.435TrpAsn: 0.435 ± 0.035
0.496TrpPro: 0.496 ± 0.038
1.066TrpGln: 1.066 ± 0.06
0.742TrpArg: 0.742 ± 0.051
0.717TrpSer: 0.717 ± 0.041
0.378TrpThr: 0.378 ± 0.033
0.663TrpVal: 0.663 ± 0.044
0.167TrpTrp: 0.167 ± 0.021
0.391TrpTyr: 0.391 ± 0.032
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.282TyrAla: 2.282 ± 0.088
0.526TyrCys: 0.526 ± 0.037
1.729TyrAsp: 1.729 ± 0.069
1.498TyrGlu: 1.498 ± 0.053
1.435TyrPhe: 1.435 ± 0.068
2.103TyrGly: 2.103 ± 0.071
0.975TyrHis: 0.975 ± 0.058
2.125TyrIle: 2.125 ± 0.07
1.363TyrLys: 1.363 ± 0.064
3.677TyrLeu: 3.677 ± 0.102
0.634TyrMet: 0.634 ± 0.038
1.432TyrAsn: 1.432 ± 0.056
1.287TyrPro: 1.287 ± 0.053
2.154TyrGln: 2.154 ± 0.083
1.926TyrArg: 1.926 ± 0.079
1.862TyrSer: 1.862 ± 0.072
1.439TyrThr: 1.439 ± 0.06
1.665TyrVal: 1.665 ± 0.055
0.452TyrTrp: 0.452 ± 0.037
1.137TyrTyr: 1.137 ± 0.053
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1589 proteins (407097 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski