Amino acid dipepetide frequency for Aglaonema bacilliform virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.438AlaAla: 2.438 ± 1.131
0.0AlaCys: 0.0 ± 0.0
1.95AlaAsp: 1.95 ± 1.827
3.901AlaGlu: 3.901 ± 1.41
1.95AlaPhe: 1.95 ± 0.905
0.488AlaGly: 0.488 ± 0.226
0.488AlaHis: 0.488 ± 0.226
5.363AlaIle: 5.363 ± 5.632
2.925AlaLys: 2.925 ± 6.453
4.876AlaLeu: 4.876 ± 2.262
1.463AlaMet: 1.463 ± 0.679
1.95AlaAsn: 1.95 ± 1.563
1.95AlaPro: 1.95 ± 0.905
3.413AlaGln: 3.413 ± 1.474
1.95AlaArg: 1.95 ± 0.905
5.363AlaSer: 5.363 ± 1.432
3.413AlaThr: 3.413 ± 1.474
2.925AlaVal: 2.925 ± 1.357
0.488AlaTrp: 0.488 ± 1.995
2.925AlaTyr: 2.925 ± 1.568
0.0AlaXaa: 0.0 ± 0.0
Cys
1.463CysAla: 1.463 ± 0.679
1.463CysCys: 1.463 ± 0.679
0.0CysAsp: 0.0 ± 0.0
0.488CysGlu: 0.488 ± 0.226
0.975CysPhe: 0.975 ± 0.452
0.488CysGly: 0.488 ± 0.226
0.488CysHis: 0.488 ± 0.226
0.488CysIle: 0.488 ± 0.226
2.438CysLys: 2.438 ± 1.131
1.95CysLeu: 1.95 ± 1.563
0.488CysMet: 0.488 ± 0.226
0.975CysAsn: 0.975 ± 0.452
0.488CysPro: 0.488 ± 0.226
0.975CysGln: 0.975 ± 0.452
0.975CysArg: 0.975 ± 0.452
0.0CysSer: 0.0 ± 0.0
0.975CysThr: 0.975 ± 0.452
1.95CysVal: 1.95 ± 1.827
0.0CysTrp: 0.0 ± 0.0
0.488CysTyr: 0.488 ± 0.226
0.0CysXaa: 0.0 ± 0.0
Asp
1.95AspAla: 1.95 ± 0.905
1.463AspCys: 1.463 ± 0.679
4.388AspAsp: 4.388 ± 2.036
2.438AspGlu: 2.438 ± 1.131
1.95AspPhe: 1.95 ± 1.827
2.925AspGly: 2.925 ± 1.357
0.975AspHis: 0.975 ± 0.452
4.876AspIle: 4.876 ± 2.262
2.438AspLys: 2.438 ± 1.131
6.338AspLeu: 6.338 ± 0.863
0.0AspMet: 0.0 ± 0.0
2.925AspAsn: 2.925 ± 1.357
3.901AspPro: 3.901 ± 1.81
1.463AspGln: 1.463 ± 0.679
2.925AspArg: 2.925 ± 1.388
1.95AspSer: 1.95 ± 0.905
3.901AspThr: 3.901 ± 1.81
1.463AspVal: 1.463 ± 0.679
0.975AspTrp: 0.975 ± 0.452
2.925AspTyr: 2.925 ± 1.357
0.0AspXaa: 0.0 ± 0.0
Glu
4.876GluAla: 4.876 ± 3.908
0.975GluCys: 0.975 ± 0.452
4.876GluAsp: 4.876 ± 1.388
10.726GluGlu: 10.726 ± 3.466
1.463GluPhe: 1.463 ± 0.679
4.388GluGly: 4.388 ± 2.036
1.463GluHis: 1.463 ± 0.679
2.925GluIle: 2.925 ± 2.446
7.314GluLys: 7.314 ± 9.794
6.338GluLeu: 6.338 ± 2.878
0.488GluMet: 0.488 ± 0.226
2.925GluAsn: 2.925 ± 1.357
1.95GluPro: 1.95 ± 2.898
2.925GluGln: 2.925 ± 2.446
2.438GluArg: 2.438 ± 1.131
3.901GluSer: 3.901 ± 3.125
1.95GluThr: 1.95 ± 0.905
4.876GluVal: 4.876 ± 3.375
1.95GluTrp: 1.95 ± 1.563
4.388GluTyr: 4.388 ± 1.387
0.0GluXaa: 0.0 ± 0.0
Phe
1.463PheAla: 1.463 ± 1.983
0.975PheCys: 0.975 ± 0.452
1.95PheAsp: 1.95 ± 0.905
1.95PheGlu: 1.95 ± 0.905
0.488PhePhe: 0.488 ± 0.226
0.488PheGly: 0.488 ± 0.226
1.463PheHis: 1.463 ± 0.679
3.901PheIle: 3.901 ± 1.81
2.438PheLys: 2.438 ± 1.461
2.925PheLeu: 2.925 ± 1.357
0.0PheMet: 0.0 ± 0.0
1.95PheAsn: 1.95 ± 0.905
0.488PhePro: 0.488 ± 0.226
3.413PheGln: 3.413 ± 1.351
1.95PheArg: 1.95 ± 1.563
1.463PheSer: 1.463 ± 0.679
2.438PheThr: 2.438 ± 1.687
0.488PheVal: 0.488 ± 0.226
0.975PheTrp: 0.975 ± 0.452
1.463PheTyr: 1.463 ± 0.679
0.0PheXaa: 0.0 ± 0.0
Gly
2.438GlyAla: 2.438 ± 1.687
0.975GlyCys: 0.975 ± 0.452
2.438GlyAsp: 2.438 ± 1.131
3.413GlyGlu: 3.413 ± 1.584
2.438GlyPhe: 2.438 ± 1.687
1.463GlyGly: 1.463 ± 0.679
1.95GlyHis: 1.95 ± 1.563
3.901GlyIle: 3.901 ± 1.81
2.438GlyLys: 2.438 ± 1.131
3.901GlyLeu: 3.901 ± 3.654
0.488GlyMet: 0.488 ± 0.226
2.438GlyAsn: 2.438 ± 1.131
2.438GlyPro: 2.438 ± 1.687
1.95GlyGln: 1.95 ± 0.905
1.95GlyArg: 1.95 ± 0.905
2.438GlySer: 2.438 ± 1.131
1.95GlyThr: 1.95 ± 1.827
2.438GlyVal: 2.438 ± 1.131
0.975GlyTrp: 0.975 ± 0.452
2.438GlyTyr: 2.438 ± 1.131
0.0GlyXaa: 0.0 ± 0.0
His
1.463HisAla: 1.463 ± 0.679
0.488HisCys: 0.488 ± 0.226
1.463HisAsp: 1.463 ± 0.679
2.925HisGlu: 2.925 ± 1.357
1.463HisPhe: 1.463 ± 0.679
0.975HisGly: 0.975 ± 0.452
0.488HisHis: 0.488 ± 0.226
3.413HisIle: 3.413 ± 1.584
1.463HisLys: 1.463 ± 0.679
4.388HisLeu: 4.388 ± 1.387
0.0HisMet: 0.0 ± 0.0
2.925HisAsn: 2.925 ± 1.388
0.975HisPro: 0.975 ± 0.452
0.488HisGln: 0.488 ± 0.226
1.95HisArg: 1.95 ± 0.905
1.463HisSer: 1.463 ± 0.679
1.463HisThr: 1.463 ± 1.689
0.975HisVal: 0.975 ± 0.452
0.0HisTrp: 0.0 ± 0.0
1.463HisTyr: 1.463 ± 0.679
0.0HisXaa: 0.0 ± 0.0
Ile
2.925IleAla: 2.925 ± 1.357
1.463IleCys: 1.463 ± 0.679
2.925IleAsp: 2.925 ± 1.357
8.289IleGlu: 8.289 ± 5.607
2.438IlePhe: 2.438 ± 1.131
3.901IleGly: 3.901 ± 1.41
2.438IleHis: 2.438 ± 1.131
5.851IleIle: 5.851 ± 1.686
4.388IleLys: 4.388 ± 3.51
8.776IleLeu: 8.776 ± 0.271
1.463IleMet: 1.463 ± 0.679
3.413IleAsn: 3.413 ± 1.474
7.801IlePro: 7.801 ± 2.049
5.363IleGln: 5.363 ± 2.488
2.438IleArg: 2.438 ± 1.131
6.338IleSer: 6.338 ± 2.941
6.338IleThr: 6.338 ± 3.035
3.901IleVal: 3.901 ± 1.81
0.975IleTrp: 0.975 ± 0.452
1.95IleTyr: 1.95 ± 1.563
0.0IleXaa: 0.0 ± 0.0
Lys
2.925LysAla: 2.925 ± 1.568
1.463LysCys: 1.463 ± 1.983
2.925LysAsp: 2.925 ± 1.357
3.901LysGlu: 3.901 ± 9.292
2.925LysPhe: 2.925 ± 1.357
2.438LysGly: 2.438 ± 1.131
1.95LysHis: 1.95 ± 0.905
6.826LysIle: 6.826 ± 2.679
4.388LysLys: 4.388 ± 1.767
6.826LysLeu: 6.826 ± 9.158
1.95LysMet: 1.95 ± 0.905
4.876LysAsn: 4.876 ± 5.344
1.463LysPro: 1.463 ± 1.983
3.901LysGln: 3.901 ± 4.333
4.388LysArg: 4.388 ± 1.387
4.388LysSer: 4.388 ± 5.57
2.438LysThr: 2.438 ± 1.687
2.438LysVal: 2.438 ± 1.687
0.975LysTrp: 0.975 ± 1.835
2.438LysTyr: 2.438 ± 1.131
0.0LysXaa: 0.0 ± 0.0
Leu
3.901LeuAla: 3.901 ± 1.41
2.438LeuCys: 2.438 ± 1.131
6.826LeuAsp: 6.826 ± 1.991
7.314LeuGlu: 7.314 ± 12.226
2.925LeuPhe: 2.925 ± 1.388
5.851LeuGly: 5.851 ± 3.49
3.413LeuHis: 3.413 ± 1.584
6.338LeuIle: 6.338 ± 0.863
5.851LeuLys: 5.851 ± 4.891
7.801LeuLeu: 7.801 ± 4.935
0.488LeuMet: 0.488 ± 0.226
3.413LeuAsn: 3.413 ± 1.584
5.363LeuPro: 5.363 ± 2.488
6.338LeuGln: 6.338 ± 2.878
5.363LeuArg: 5.363 ± 1.432
6.826LeuSer: 6.826 ± 6.993
4.876LeuThr: 4.876 ± 1.459
4.388LeuVal: 4.388 ± 2.036
0.0LeuTrp: 0.0 ± 0.0
2.438LeuTyr: 2.438 ± 1.131
0.0LeuXaa: 0.0 ± 0.0
Met
0.975MetAla: 0.975 ± 0.452
0.488MetCys: 0.488 ± 0.226
0.975MetAsp: 0.975 ± 0.452
0.975MetGlu: 0.975 ± 0.452
0.488MetPhe: 0.488 ± 0.226
0.488MetGly: 0.488 ± 0.226
0.975MetHis: 0.975 ± 0.452
0.0MetIle: 0.0 ± 0.0
0.975MetLys: 0.975 ± 0.452
1.95MetLeu: 1.95 ± 0.905
0.488MetMet: 0.488 ± 0.226
1.463MetAsn: 1.463 ± 0.679
1.463MetPro: 1.463 ± 0.679
1.95MetGln: 1.95 ± 0.905
0.488MetArg: 0.488 ± 0.226
2.925MetSer: 2.925 ± 2.446
1.463MetThr: 1.463 ± 0.679
0.488MetVal: 0.488 ± 0.226
0.0MetTrp: 0.0 ± 0.0
0.488MetTyr: 0.488 ± 0.226
0.0MetXaa: 0.0 ± 0.0
Asn
1.463AsnAla: 1.463 ± 1.983
0.488AsnCys: 0.488 ± 0.226
1.95AsnAsp: 1.95 ± 0.905
2.438AsnGlu: 2.438 ± 1.461
0.975AsnPhe: 0.975 ± 1.835
0.488AsnGly: 0.488 ± 0.226
0.0AsnHis: 0.0 ± 0.0
5.851AsnIle: 5.851 ± 2.715
4.388AsnLys: 4.388 ± 1.387
6.338AsnLeu: 6.338 ± 4.665
0.975AsnMet: 0.975 ± 0.452
0.488AsnAsn: 0.488 ± 2.329
2.438AsnPro: 2.438 ± 2.672
2.438AsnGln: 2.438 ± 1.131
0.488AsnArg: 0.488 ± 0.226
4.876AsnSer: 4.876 ± 2.262
5.363AsnThr: 5.363 ± 1.432
1.463AsnVal: 1.463 ± 0.679
0.488AsnTrp: 0.488 ± 0.226
2.925AsnTyr: 2.925 ± 1.357
0.0AsnXaa: 0.0 ± 0.0
Pro
3.413ProAla: 3.413 ± 3.806
0.488ProCys: 0.488 ± 0.226
4.876ProAsp: 4.876 ± 2.262
2.438ProGlu: 2.438 ± 1.687
1.463ProPhe: 1.463 ± 0.679
3.413ProGly: 3.413 ± 1.584
1.463ProHis: 1.463 ± 0.679
2.438ProIle: 2.438 ± 1.131
1.95ProLys: 1.95 ± 2.898
3.901ProLeu: 3.901 ± 1.81
1.95ProMet: 1.95 ± 0.838
0.975ProAsn: 0.975 ± 0.452
4.388ProPro: 4.388 ± 2.036
4.388ProGln: 4.388 ± 2.036
0.488ProArg: 0.488 ± 0.226
5.851ProSer: 5.851 ± 2.715
5.363ProThr: 5.363 ± 1.315
0.975ProVal: 0.975 ± 0.452
0.0ProTrp: 0.0 ± 0.0
2.925ProTyr: 2.925 ± 1.357
0.0ProXaa: 0.0 ± 0.0
Gln
3.901GlnAla: 3.901 ± 1.41
0.0GlnCys: 0.0 ± 0.0
2.438GlnAsp: 2.438 ± 1.131
5.851GlnGlu: 5.851 ± 1.508
0.488GlnPhe: 0.488 ± 1.995
3.413GlnGly: 3.413 ± 1.584
3.413GlnHis: 3.413 ± 1.584
5.363GlnIle: 5.363 ± 3.25
4.388GlnLys: 4.388 ± 7.186
6.826GlnLeu: 6.826 ± 1.742
0.975GlnMet: 0.975 ± 1.33
2.438GlnAsn: 2.438 ± 1.687
2.438GlnPro: 2.438 ± 1.131
5.363GlnGln: 5.363 ± 2.841
4.388GlnArg: 4.388 ± 2.036
1.463GlnSer: 1.463 ± 1.689
0.488GlnThr: 0.488 ± 0.226
3.413GlnVal: 3.413 ± 1.584
0.488GlnTrp: 0.488 ± 0.226
1.463GlnTyr: 1.463 ± 0.679
0.0GlnXaa: 0.0 ± 0.0
Arg
2.925ArgAla: 2.925 ± 1.357
0.488ArgCys: 0.488 ± 0.226
1.95ArgAsp: 1.95 ± 0.905
2.925ArgGlu: 2.925 ± 1.388
0.488ArgPhe: 0.488 ± 0.226
0.975ArgGly: 0.975 ± 0.452
0.975ArgHis: 0.975 ± 0.452
4.876ArgIle: 4.876 ± 2.262
3.901ArgLys: 3.901 ± 1.81
5.363ArgLeu: 5.363 ± 1.56
2.925ArgMet: 2.925 ± 1.357
3.901ArgAsn: 3.901 ± 1.81
4.388ArgPro: 4.388 ± 2.036
1.463ArgGln: 1.463 ± 0.679
2.438ArgArg: 2.438 ± 1.461
3.413ArgSer: 3.413 ± 1.584
2.438ArgThr: 2.438 ± 1.131
3.413ArgVal: 3.413 ± 4.133
1.95ArgTrp: 1.95 ± 1.563
0.975ArgTyr: 0.975 ± 0.452
0.0ArgXaa: 0.0 ± 0.0
Ser
1.95SerAla: 1.95 ± 0.905
1.95SerCys: 1.95 ± 0.905
1.95SerAsp: 1.95 ± 0.905
3.901SerGlu: 3.901 ± 1.41
3.413SerPhe: 3.413 ± 1.584
3.413SerGly: 3.413 ± 1.474
1.95SerHis: 1.95 ± 1.563
6.338SerIle: 6.338 ± 2.941
3.413SerLys: 3.413 ± 1.474
5.363SerLeu: 5.363 ± 6.895
0.975SerMet: 0.975 ± 0.452
2.438SerAsn: 2.438 ± 1.131
4.876SerPro: 4.876 ± 2.262
3.901SerGln: 3.901 ± 1.81
6.338SerArg: 6.338 ± 2.73
7.314SerSer: 7.314 ± 2.691
4.388SerThr: 4.388 ± 1.767
3.413SerVal: 3.413 ± 5.353
0.488SerTrp: 0.488 ± 0.226
1.95SerTyr: 1.95 ± 1.827
0.0SerXaa: 0.0 ± 0.0
Thr
4.876ThrAla: 4.876 ± 3.908
0.488ThrCys: 0.488 ± 0.226
3.413ThrAsp: 3.413 ± 1.584
4.388ThrGlu: 4.388 ± 1.387
0.488ThrPhe: 0.488 ± 0.226
4.876ThrGly: 4.876 ± 3.375
1.95ThrHis: 1.95 ± 0.905
5.363ThrIle: 5.363 ± 2.488
4.388ThrLys: 4.388 ± 6.594
2.438ThrLeu: 2.438 ± 1.687
1.95ThrMet: 1.95 ± 1.045
1.95ThrAsn: 1.95 ± 1.827
0.975ThrPro: 0.975 ± 0.452
6.826ThrGln: 6.826 ± 0.637
2.925ThrArg: 2.925 ± 1.357
3.413ThrSer: 3.413 ± 1.584
3.413ThrThr: 3.413 ± 1.584
0.975ThrVal: 0.975 ± 0.452
0.488ThrTrp: 0.488 ± 0.226
2.925ThrTyr: 2.925 ± 1.357
0.0ThrXaa: 0.0 ± 0.0
Val
1.95ValAla: 1.95 ± 0.905
0.975ValCys: 0.975 ± 1.835
1.95ValAsp: 1.95 ± 0.905
1.463ValGlu: 1.463 ± 0.679
5.363ValPhe: 5.363 ± 2.488
1.463ValGly: 1.463 ± 0.679
2.925ValHis: 2.925 ± 1.388
4.388ValIle: 4.388 ± 1.767
2.438ValLys: 2.438 ± 1.687
1.463ValLeu: 1.463 ± 1.983
1.463ValMet: 1.463 ± 0.679
1.95ValAsn: 1.95 ± 3.669
1.463ValPro: 1.463 ± 0.679
0.488ValGln: 0.488 ± 0.226
4.388ValArg: 4.388 ± 2.036
3.413ValSer: 3.413 ± 1.351
2.925ValThr: 2.925 ± 1.568
1.463ValVal: 1.463 ± 0.679
0.488ValTrp: 0.488 ± 0.226
1.463ValTyr: 1.463 ± 1.983
0.0ValXaa: 0.0 ± 0.0
Trp
0.488TrpAla: 0.488 ± 0.226
0.488TrpCys: 0.488 ± 0.226
0.488TrpAsp: 0.488 ± 0.226
1.463TrpGlu: 1.463 ± 1.689
0.0TrpPhe: 0.0 ± 0.0
0.488TrpGly: 0.488 ± 0.226
0.488TrpHis: 0.488 ± 0.226
1.95TrpIle: 1.95 ± 0.905
0.975TrpLys: 0.975 ± 1.835
0.975TrpLeu: 0.975 ± 0.452
0.0TrpMet: 0.0 ± 0.0
0.488TrpAsn: 0.488 ± 0.226
0.488TrpPro: 0.488 ± 0.226
0.488TrpGln: 0.488 ± 0.226
0.975TrpArg: 0.975 ± 0.452
0.0TrpSer: 0.0 ± 0.0
1.463TrpThr: 1.463 ± 0.679
0.488TrpVal: 0.488 ± 1.995
0.488TrpTrp: 0.488 ± 0.226
0.975TrpTyr: 0.975 ± 1.835
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.438TyrAla: 2.438 ± 1.131
0.0TyrCys: 0.0 ± 0.0
2.438TyrAsp: 2.438 ± 1.461
1.95TyrGlu: 1.95 ± 0.905
0.488TyrPhe: 0.488 ± 0.226
2.438TyrGly: 2.438 ± 1.131
0.975TyrHis: 0.975 ± 0.452
2.925TyrIle: 2.925 ± 1.568
2.925TyrLys: 2.925 ± 1.568
3.413TyrLeu: 3.413 ± 1.351
0.488TyrMet: 0.488 ± 0.226
2.438TyrAsn: 2.438 ± 1.131
3.413TyrPro: 3.413 ± 1.584
1.95TyrGln: 1.95 ± 1.827
2.925TyrArg: 2.925 ± 1.357
2.925TyrSer: 2.925 ± 1.357
1.463TyrThr: 1.463 ± 1.689
1.95TyrVal: 1.95 ± 0.905
1.463TyrTrp: 1.463 ± 0.679
2.925TyrTyr: 2.925 ± 1.357
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (2052 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski