Human parvovirus B19 (strain HV) (HPV B19)

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Quintoviricetes; Piccovirales; Parvoviridae; Parvovirinae; Erythroparvovirus; Primate erythroparvovirus 1; Human parvovirus B19

Average proteome isoelectric point is 7.33

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 6 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>sp|Q9PZT0-2|CAPSD-2_PAVHV Isoform of Q9PZT0 Isoform Major capsid protein VP2 of Minor capsid protein VP1 OS=Human parvovirus B19 (strain HV) OX=648237 GN=vp PE=1 SV=1
MM1 pKa = 7.42EE2 pKa = 5.69LFRR5 pKa = 11.84GVLQVSSNVLDD16 pKa = 4.09CANDD20 pKa = 3.54NWWCSLLDD28 pKa = 4.52LDD30 pKa = 4.58TSDD33 pKa = 4.51WEE35 pKa = 4.51PLTHH39 pKa = 6.33TNRR42 pKa = 11.84LMAIYY47 pKa = 9.89LSSVASKK54 pKa = 11.22LDD56 pKa = 3.69FTGGPLAGCLYY67 pKa = 10.0FFQVEE72 pKa = 4.38CNKK75 pKa = 10.02FEE77 pKa = 4.32EE78 pKa = 6.0GYY80 pKa = 10.13HH81 pKa = 4.95IHH83 pKa = 6.23VVIGGPGLNPRR94 pKa = 11.84NLTVCVEE101 pKa = 4.15GLFNNVLYY109 pKa = 10.84HH110 pKa = 7.15LVTEE114 pKa = 4.21NVKK117 pKa = 10.88LKK119 pKa = 9.87FLPGMTTKK127 pKa = 10.67GKK129 pKa = 9.46YY130 pKa = 9.84FRR132 pKa = 11.84DD133 pKa = 3.76GEE135 pKa = 4.32QFIEE139 pKa = 4.17NYY141 pKa = 9.96LMKK144 pKa = 10.45KK145 pKa = 9.83IPLNVVWCVTNIDD158 pKa = 4.51GYY160 pKa = 10.72IDD162 pKa = 3.5TCISATFRR170 pKa = 11.84RR171 pKa = 11.84GACHH175 pKa = 6.39AKK177 pKa = 10.11KK178 pKa = 10.17PRR180 pKa = 11.84ITTAINDD187 pKa = 3.84TSSDD191 pKa = 3.41AGEE194 pKa = 4.2SSGTGAEE201 pKa = 3.92VVPINGKK208 pKa = 6.92GTKK211 pKa = 10.13ASIKK215 pKa = 9.62FQTMVNWLCEE225 pKa = 3.97NRR227 pKa = 11.84VFTEE231 pKa = 4.36DD232 pKa = 2.61KK233 pKa = 10.24WKK235 pKa = 10.84LVDD238 pKa = 4.25FNQYY242 pKa = 8.33TLLSSSHH249 pKa = 6.29SGSFQIQSALKK260 pKa = 9.41LAIYY264 pKa = 10.0KK265 pKa = 8.2ATNLVPTSTFLLHH278 pKa = 6.7TDD280 pKa = 4.73FEE282 pKa = 4.74QVMCIKK288 pKa = 10.5DD289 pKa = 3.64NKK291 pKa = 9.48IVKK294 pKa = 10.06LLLCQNYY301 pKa = 10.3DD302 pKa = 3.57PLLVGQHH309 pKa = 4.24VLKK312 pKa = 10.54WIDD315 pKa = 3.44KK316 pKa = 10.25KK317 pKa = 11.02CGKK320 pKa = 10.44KK321 pKa = 8.43NTLWFYY327 pKa = 10.95GPPSTGKK334 pKa = 8.67TNLAMAIAKK343 pKa = 8.26SVPVYY348 pKa = 11.35GMVNWNNEE356 pKa = 3.9NFPFNDD362 pKa = 3.11VAGKK366 pKa = 10.34SLVVWDD372 pKa = 4.04EE373 pKa = 4.53GIIKK377 pKa = 8.56STIVEE382 pKa = 3.9AAKK385 pKa = 10.54AILGGQPTRR394 pKa = 11.84VDD396 pKa = 2.94QKK398 pKa = 9.77MRR400 pKa = 11.84GSVAVPGVPVVITSNGDD417 pKa = 2.82ITFVVSGNTTTTVHH431 pKa = 6.73AKK433 pKa = 9.85ALKK436 pKa = 10.0EE437 pKa = 3.91RR438 pKa = 11.84MVKK441 pKa = 10.64LNFTVRR447 pKa = 11.84CSPDD451 pKa = 2.98MGLLTEE457 pKa = 5.44ADD459 pKa = 3.75VQQWLTWCNAQSWDD473 pKa = 4.16HH474 pKa = 5.84YY475 pKa = 10.07EE476 pKa = 3.7NWAINYY482 pKa = 7.53TFDD485 pKa = 4.51FPGINADD492 pKa = 3.84ALHH495 pKa = 7.51PDD497 pKa = 3.8LQTTPIVTDD506 pKa = 3.41TSISSSGGEE515 pKa = 3.93SSEE518 pKa = 4.12EE519 pKa = 3.7LSEE522 pKa = 4.59SSFFNLITPGAWNTEE537 pKa = 4.41TPRR540 pKa = 11.84SSTPIPGTSSGEE552 pKa = 4.22SFVGSSVSSEE562 pKa = 3.84VVAASWEE569 pKa = 4.22EE570 pKa = 3.88AFYY573 pKa = 10.7TPLADD578 pKa = 3.63QFRR581 pKa = 11.84EE582 pKa = 4.0LLVGVDD588 pKa = 3.93YY589 pKa = 11.4VWDD592 pKa = 4.18GVRR595 pKa = 11.84GLPVCCVQHH604 pKa = 6.43INNSGGGLGLCPHH617 pKa = 7.82CINVGAWYY625 pKa = 10.11NGWKK629 pKa = 9.97FRR631 pKa = 11.84EE632 pKa = 4.2FTPDD636 pKa = 3.72LVRR639 pKa = 11.84CSCHH643 pKa = 6.95VGASNPFSVLTCKK656 pKa = 10.3KK657 pKa = 9.69CAYY660 pKa = 10.47LSGLQSFVDD669 pKa = 4.03YY670 pKa = 10.7EE671 pKa = 4.05

Molecular weight: 74.07 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>sp|P0DJZ0|11K_PAVHV Host-modulation protein 11K OS=Human parvovirus B19 (strain HV) OX=648237 GN=11K PE=1 SV=1
MM1 pKa = 7.29QMPSTQTSKK10 pKa = 10.77PPQLSQTPVSAAVVVKK26 pKa = 10.53ALKK29 pKa = 10.54NSVKK33 pKa = 10.5AAFLTSSPQAPGTLKK48 pKa = 10.27PRR50 pKa = 11.84ALVRR54 pKa = 11.84PSPGPVQEE62 pKa = 4.2NHH64 pKa = 6.39LSEE67 pKa = 4.77AQFPPKK73 pKa = 10.4LL74 pKa = 3.64

Molecular weight: 7.8 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

5

1

6

2255

74

781

375.8

41.48

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.987 ± 0.579

1.596 ± 0.718

4.169 ± 0.61

4.745 ± 0.364

3.858 ± 0.54

8.115 ± 0.961

3.193 ± 0.522

3.769 ± 0.56

5.543 ± 0.477

8.603 ± 0.756

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.173 ± 0.726

4.922 ± 0.511

7.361 ± 1.455

4.789 ± 0.76

2.661 ± 0.326

8.204 ± 0.729

7.273 ± 0.337

6.874 ± 0.775

1.863 ± 0.396

4.302 ± 0.707
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski