Amino acid dipepetide frequency for Hubei picorna-like virus 48

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.469AlaAla: 8.469 ± 0.0
1.016AlaCys: 1.016 ± 0.0
3.388AlaAsp: 3.388 ± 0.0
7.791AlaGlu: 7.791 ± 0.0
2.371AlaPhe: 2.371 ± 0.0
4.065AlaGly: 4.065 ± 0.0
4.065AlaHis: 4.065 ± 0.0
5.081AlaIle: 5.081 ± 0.0
3.049AlaLys: 3.049 ± 0.0
7.453AlaLeu: 7.453 ± 0.0
3.049AlaMet: 3.049 ± 0.0
3.049AlaAsn: 3.049 ± 0.0
3.388AlaPro: 3.388 ± 0.0
1.355AlaGln: 1.355 ± 0.0
4.065AlaArg: 4.065 ± 0.0
3.388AlaSer: 3.388 ± 0.0
3.049AlaThr: 3.049 ± 0.0
4.743AlaVal: 4.743 ± 0.0
1.016AlaTrp: 1.016 ± 0.0
2.371AlaTyr: 2.371 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.339CysAla: 0.339 ± 0.0
0.339CysCys: 0.339 ± 0.0
1.694CysAsp: 1.694 ± 0.0
0.678CysGlu: 0.678 ± 0.0
0.0CysPhe: 0.0 ± 0.0
1.355CysGly: 1.355 ± 0.0
1.016CysHis: 1.016 ± 0.0
0.678CysIle: 0.678 ± 0.0
1.694CysLys: 1.694 ± 0.0
1.355CysLeu: 1.355 ± 0.0
0.0CysMet: 0.0 ± 0.0
1.355CysAsn: 1.355 ± 0.0
0.339CysPro: 0.339 ± 0.0
0.339CysGln: 0.339 ± 0.0
0.339CysArg: 0.339 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.339CysVal: 0.339 ± 0.0
0.339CysTrp: 0.339 ± 0.0
1.694CysTyr: 1.694 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.065AspAla: 4.065 ± 0.0
0.339AspCys: 0.339 ± 0.0
4.743AspAsp: 4.743 ± 0.0
5.42AspGlu: 5.42 ± 0.0
3.388AspPhe: 3.388 ± 0.0
1.694AspGly: 1.694 ± 0.0
1.355AspHis: 1.355 ± 0.0
1.694AspIle: 1.694 ± 0.0
2.71AspLys: 2.71 ± 0.0
3.726AspLeu: 3.726 ± 0.0
1.694AspMet: 1.694 ± 0.0
2.371AspAsn: 2.371 ± 0.0
2.033AspPro: 2.033 ± 0.0
3.388AspGln: 3.388 ± 0.0
2.71AspArg: 2.71 ± 0.0
1.694AspSer: 1.694 ± 0.0
3.049AspThr: 3.049 ± 0.0
6.098AspVal: 6.098 ± 0.0
0.339AspTrp: 0.339 ± 0.0
2.371AspTyr: 2.371 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
6.436GluAla: 6.436 ± 0.0
0.339GluCys: 0.339 ± 0.0
3.049GluAsp: 3.049 ± 0.0
10.163GluGlu: 10.163 ± 0.0
3.049GluPhe: 3.049 ± 0.0
5.42GluGly: 5.42 ± 0.0
0.339GluHis: 0.339 ± 0.0
3.049GluIle: 3.049 ± 0.0
3.388GluLys: 3.388 ± 0.0
6.436GluLeu: 6.436 ± 0.0
3.726GluMet: 3.726 ± 0.0
3.726GluAsn: 3.726 ± 0.0
2.371GluPro: 2.371 ± 0.0
1.355GluGln: 1.355 ± 0.0
3.726GluArg: 3.726 ± 0.0
4.404GluSer: 4.404 ± 0.0
2.71GluThr: 2.71 ± 0.0
5.759GluVal: 5.759 ± 0.0
2.71GluTrp: 2.71 ± 0.0
2.371GluTyr: 2.371 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
1.694PheAla: 1.694 ± 0.0
0.339PheCys: 0.339 ± 0.0
3.049PheAsp: 3.049 ± 0.0
3.049PheGlu: 3.049 ± 0.0
3.049PhePhe: 3.049 ± 0.0
2.033PheGly: 2.033 ± 0.0
1.016PheHis: 1.016 ± 0.0
4.743PheIle: 4.743 ± 0.0
3.049PheLys: 3.049 ± 0.0
3.388PheLeu: 3.388 ± 0.0
1.355PheMet: 1.355 ± 0.0
2.71PheAsn: 2.71 ± 0.0
2.033PhePro: 2.033 ± 0.0
2.71PheGln: 2.71 ± 0.0
2.033PheArg: 2.033 ± 0.0
2.033PheSer: 2.033 ± 0.0
4.404PheThr: 4.404 ± 0.0
3.388PheVal: 3.388 ± 0.0
0.339PheTrp: 0.339 ± 0.0
1.694PheTyr: 1.694 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
3.388GlyAla: 3.388 ± 0.0
1.016GlyCys: 1.016 ± 0.0
3.726GlyAsp: 3.726 ± 0.0
4.743GlyGlu: 4.743 ± 0.0
3.388GlyPhe: 3.388 ± 0.0
2.71GlyGly: 2.71 ± 0.0
1.355GlyHis: 1.355 ± 0.0
5.42GlyIle: 5.42 ± 0.0
5.081GlyLys: 5.081 ± 0.0
5.42GlyLeu: 5.42 ± 0.0
1.694GlyMet: 1.694 ± 0.0
2.71GlyAsn: 2.71 ± 0.0
1.694GlyPro: 1.694 ± 0.0
2.033GlyGln: 2.033 ± 0.0
2.71GlyArg: 2.71 ± 0.0
3.726GlySer: 3.726 ± 0.0
2.371GlyThr: 2.371 ± 0.0
4.743GlyVal: 4.743 ± 0.0
0.678GlyTrp: 0.678 ± 0.0
2.371GlyTyr: 2.371 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
2.033HisAla: 2.033 ± 0.0
0.0HisCys: 0.0 ± 0.0
1.016HisAsp: 1.016 ± 0.0
0.678HisGlu: 0.678 ± 0.0
1.694HisPhe: 1.694 ± 0.0
1.016HisGly: 1.016 ± 0.0
0.678HisHis: 0.678 ± 0.0
1.016HisIle: 1.016 ± 0.0
1.016HisLys: 1.016 ± 0.0
1.355HisLeu: 1.355 ± 0.0
0.678HisMet: 0.678 ± 0.0
0.678HisAsn: 0.678 ± 0.0
0.339HisPro: 0.339 ± 0.0
1.016HisGln: 1.016 ± 0.0
0.678HisArg: 0.678 ± 0.0
1.694HisSer: 1.694 ± 0.0
2.371HisThr: 2.371 ± 0.0
1.355HisVal: 1.355 ± 0.0
0.0HisTrp: 0.0 ± 0.0
1.694HisTyr: 1.694 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.743IleAla: 4.743 ± 0.0
0.678IleCys: 0.678 ± 0.0
2.033IleAsp: 2.033 ± 0.0
3.726IleGlu: 3.726 ± 0.0
1.694IlePhe: 1.694 ± 0.0
1.694IleGly: 1.694 ± 0.0
1.694IleHis: 1.694 ± 0.0
1.355IleIle: 1.355 ± 0.0
0.339IleLys: 0.339 ± 0.0
5.42IleLeu: 5.42 ± 0.0
1.016IleMet: 1.016 ± 0.0
1.016IleAsn: 1.016 ± 0.0
6.098IlePro: 6.098 ± 0.0
2.033IleGln: 2.033 ± 0.0
2.371IleArg: 2.371 ± 0.0
5.42IleSer: 5.42 ± 0.0
2.71IleThr: 2.71 ± 0.0
4.065IleVal: 4.065 ± 0.0
0.678IleTrp: 0.678 ± 0.0
0.678IleTyr: 0.678 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
3.726LysAla: 3.726 ± 0.0
1.694LysCys: 1.694 ± 0.0
4.404LysAsp: 4.404 ± 0.0
3.049LysGlu: 3.049 ± 0.0
1.016LysPhe: 1.016 ± 0.0
3.726LysGly: 3.726 ± 0.0
1.355LysHis: 1.355 ± 0.0
2.033LysIle: 2.033 ± 0.0
4.404LysLys: 4.404 ± 0.0
5.42LysLeu: 5.42 ± 0.0
1.016LysMet: 1.016 ± 0.0
2.371LysAsn: 2.371 ± 0.0
1.355LysPro: 1.355 ± 0.0
2.371LysGln: 2.371 ± 0.0
2.033LysArg: 2.033 ± 0.0
5.081LysSer: 5.081 ± 0.0
4.743LysThr: 4.743 ± 0.0
2.033LysVal: 2.033 ± 0.0
0.339LysTrp: 0.339 ± 0.0
2.71LysTyr: 2.71 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
6.775LeuAla: 6.775 ± 0.0
1.694LeuCys: 1.694 ± 0.0
3.388LeuAsp: 3.388 ± 0.0
4.065LeuGlu: 4.065 ± 0.0
3.726LeuPhe: 3.726 ± 0.0
7.791LeuGly: 7.791 ± 0.0
1.016LeuHis: 1.016 ± 0.0
4.404LeuIle: 4.404 ± 0.0
5.759LeuLys: 5.759 ± 0.0
5.759LeuLeu: 5.759 ± 0.0
1.694LeuMet: 1.694 ± 0.0
3.049LeuAsn: 3.049 ± 0.0
5.081LeuPro: 5.081 ± 0.0
2.371LeuGln: 2.371 ± 0.0
6.098LeuArg: 6.098 ± 0.0
4.743LeuSer: 4.743 ± 0.0
6.098LeuThr: 6.098 ± 0.0
5.759LeuVal: 5.759 ± 0.0
0.339LeuTrp: 0.339 ± 0.0
2.371LeuTyr: 2.371 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
3.726MetAla: 3.726 ± 0.0
0.678MetCys: 0.678 ± 0.0
1.355MetAsp: 1.355 ± 0.0
3.049MetGlu: 3.049 ± 0.0
0.339MetPhe: 0.339 ± 0.0
0.678MetGly: 0.678 ± 0.0
0.678MetHis: 0.678 ± 0.0
1.355MetIle: 1.355 ± 0.0
3.049MetLys: 3.049 ± 0.0
1.355MetLeu: 1.355 ± 0.0
0.678MetMet: 0.678 ± 0.0
1.694MetAsn: 1.694 ± 0.0
0.678MetPro: 0.678 ± 0.0
1.016MetGln: 1.016 ± 0.0
1.355MetArg: 1.355 ± 0.0
1.016MetSer: 1.016 ± 0.0
4.065MetThr: 4.065 ± 0.0
2.371MetVal: 2.371 ± 0.0
1.016MetTrp: 1.016 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.694AsnAla: 1.694 ± 0.0
0.678AsnCys: 0.678 ± 0.0
2.371AsnAsp: 2.371 ± 0.0
2.71AsnGlu: 2.71 ± 0.0
2.371AsnPhe: 2.371 ± 0.0
3.388AsnGly: 3.388 ± 0.0
0.339AsnHis: 0.339 ± 0.0
2.033AsnIle: 2.033 ± 0.0
3.049AsnLys: 3.049 ± 0.0
2.033AsnLeu: 2.033 ± 0.0
0.0AsnMet: 0.0 ± 0.0
3.049AsnAsn: 3.049 ± 0.0
1.355AsnPro: 1.355 ± 0.0
2.033AsnGln: 2.033 ± 0.0
2.71AsnArg: 2.71 ± 0.0
1.694AsnSer: 1.694 ± 0.0
5.759AsnThr: 5.759 ± 0.0
1.694AsnVal: 1.694 ± 0.0
1.355AsnTrp: 1.355 ± 0.0
3.388AsnTyr: 3.388 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
3.388ProAla: 3.388 ± 0.0
0.678ProCys: 0.678 ± 0.0
1.694ProAsp: 1.694 ± 0.0
2.71ProGlu: 2.71 ± 0.0
1.694ProPhe: 1.694 ± 0.0
4.065ProGly: 4.065 ± 0.0
2.033ProHis: 2.033 ± 0.0
1.355ProIle: 1.355 ± 0.0
0.678ProLys: 0.678 ± 0.0
3.049ProLeu: 3.049 ± 0.0
0.678ProMet: 0.678 ± 0.0
3.049ProAsn: 3.049 ± 0.0
2.371ProPro: 2.371 ± 0.0
3.049ProGln: 3.049 ± 0.0
1.694ProArg: 1.694 ± 0.0
4.404ProSer: 4.404 ± 0.0
2.033ProThr: 2.033 ± 0.0
3.726ProVal: 3.726 ± 0.0
1.355ProTrp: 1.355 ± 0.0
2.371ProTyr: 2.371 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
3.388GlnAla: 3.388 ± 0.0
0.0GlnCys: 0.0 ± 0.0
3.049GlnAsp: 3.049 ± 0.0
1.355GlnGlu: 1.355 ± 0.0
2.033GlnPhe: 2.033 ± 0.0
3.726GlnGly: 3.726 ± 0.0
0.0GlnHis: 0.0 ± 0.0
2.371GlnIle: 2.371 ± 0.0
3.388GlnLys: 3.388 ± 0.0
2.033GlnLeu: 2.033 ± 0.0
2.371GlnMet: 2.371 ± 0.0
0.339GlnAsn: 0.339 ± 0.0
1.355GlnPro: 1.355 ± 0.0
1.694GlnGln: 1.694 ± 0.0
4.065GlnArg: 4.065 ± 0.0
1.694GlnSer: 1.694 ± 0.0
2.033GlnThr: 2.033 ± 0.0
2.033GlnVal: 2.033 ± 0.0
0.678GlnTrp: 0.678 ± 0.0
1.355GlnTyr: 1.355 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.033ArgAla: 2.033 ± 0.0
1.355ArgCys: 1.355 ± 0.0
3.388ArgAsp: 3.388 ± 0.0
5.081ArgGlu: 5.081 ± 0.0
3.726ArgPhe: 3.726 ± 0.0
4.743ArgGly: 4.743 ± 0.0
0.678ArgHis: 0.678 ± 0.0
3.726ArgIle: 3.726 ± 0.0
1.355ArgLys: 1.355 ± 0.0
5.081ArgLeu: 5.081 ± 0.0
1.016ArgMet: 1.016 ± 0.0
1.694ArgAsn: 1.694 ± 0.0
1.694ArgPro: 1.694 ± 0.0
2.371ArgGln: 2.371 ± 0.0
4.065ArgArg: 4.065 ± 0.0
2.033ArgSer: 2.033 ± 0.0
3.049ArgThr: 3.049 ± 0.0
4.404ArgVal: 4.404 ± 0.0
1.355ArgTrp: 1.355 ± 0.0
2.71ArgTyr: 2.71 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
2.033SerAla: 2.033 ± 0.0
1.355SerCys: 1.355 ± 0.0
3.726SerAsp: 3.726 ± 0.0
4.065SerGlu: 4.065 ± 0.0
2.71SerPhe: 2.71 ± 0.0
3.388SerGly: 3.388 ± 0.0
0.0SerHis: 0.0 ± 0.0
2.033SerIle: 2.033 ± 0.0
2.033SerLys: 2.033 ± 0.0
7.114SerLeu: 7.114 ± 0.0
2.033SerMet: 2.033 ± 0.0
3.388SerAsn: 3.388 ± 0.0
2.71SerPro: 2.71 ± 0.0
1.016SerGln: 1.016 ± 0.0
2.71SerArg: 2.71 ± 0.0
2.71SerSer: 2.71 ± 0.0
6.098SerThr: 6.098 ± 0.0
5.081SerVal: 5.081 ± 0.0
1.355SerTrp: 1.355 ± 0.0
0.678SerTyr: 0.678 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
8.13ThrAla: 8.13 ± 0.0
0.678ThrCys: 0.678 ± 0.0
2.371ThrAsp: 2.371 ± 0.0
5.081ThrGlu: 5.081 ± 0.0
4.065ThrPhe: 4.065 ± 0.0
3.388ThrGly: 3.388 ± 0.0
0.678ThrHis: 0.678 ± 0.0
2.033ThrIle: 2.033 ± 0.0
2.71ThrLys: 2.71 ± 0.0
4.743ThrLeu: 4.743 ± 0.0
1.355ThrMet: 1.355 ± 0.0
2.033ThrAsn: 2.033 ± 0.0
3.726ThrPro: 3.726 ± 0.0
2.71ThrGln: 2.71 ± 0.0
6.098ThrArg: 6.098 ± 0.0
5.42ThrSer: 5.42 ± 0.0
7.453ThrThr: 7.453 ± 0.0
7.114ThrVal: 7.114 ± 0.0
0.0ThrTrp: 0.0 ± 0.0
2.033ThrTyr: 2.033 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
8.469ValAla: 8.469 ± 0.0
0.339ValCys: 0.339 ± 0.0
4.404ValAsp: 4.404 ± 0.0
5.42ValGlu: 5.42 ± 0.0
3.388ValPhe: 3.388 ± 0.0
3.726ValGly: 3.726 ± 0.0
1.694ValHis: 1.694 ± 0.0
2.371ValIle: 2.371 ± 0.0
4.743ValLys: 4.743 ± 0.0
6.436ValLeu: 6.436 ± 0.0
3.726ValMet: 3.726 ± 0.0
3.049ValAsn: 3.049 ± 0.0
4.065ValPro: 4.065 ± 0.0
3.726ValGln: 3.726 ± 0.0
3.388ValArg: 3.388 ± 0.0
2.371ValSer: 2.371 ± 0.0
3.726ValThr: 3.726 ± 0.0
5.42ValVal: 5.42 ± 0.0
0.339ValTrp: 0.339 ± 0.0
1.016ValTyr: 1.016 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.339TrpCys: 0.339 ± 0.0
0.678TrpAsp: 0.678 ± 0.0
0.678TrpGlu: 0.678 ± 0.0
1.016TrpPhe: 1.016 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.339TrpHis: 0.339 ± 0.0
0.678TrpIle: 0.678 ± 0.0
1.355TrpLys: 1.355 ± 0.0
1.694TrpLeu: 1.694 ± 0.0
0.678TrpMet: 0.678 ± 0.0
0.339TrpAsn: 0.339 ± 0.0
0.678TrpPro: 0.678 ± 0.0
0.678TrpGln: 0.678 ± 0.0
0.339TrpArg: 0.339 ± 0.0
0.678TrpSer: 0.678 ± 0.0
3.049TrpThr: 3.049 ± 0.0
1.694TrpVal: 1.694 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.339TrpTyr: 0.339 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.694TyrAla: 1.694 ± 0.0
0.339TyrCys: 0.339 ± 0.0
1.355TyrAsp: 1.355 ± 0.0
1.016TyrGlu: 1.016 ± 0.0
3.388TyrPhe: 3.388 ± 0.0
2.371TyrGly: 2.371 ± 0.0
0.678TyrHis: 0.678 ± 0.0
2.033TyrIle: 2.033 ± 0.0
2.033TyrLys: 2.033 ± 0.0
2.71TyrLeu: 2.71 ± 0.0
1.355TyrMet: 1.355 ± 0.0
2.033TyrAsn: 2.033 ± 0.0
2.71TyrPro: 2.71 ± 0.0
1.694TyrGln: 1.694 ± 0.0
2.371TyrArg: 2.371 ± 0.0
2.033TyrSer: 2.033 ± 0.0
3.049TyrThr: 3.049 ± 0.0
0.339TyrVal: 0.339 ± 0.0
1.016TyrTrp: 1.016 ± 0.0
0.339TyrTyr: 0.339 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (2953 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski