Amino acid dipepetide frequency for Chondromyces crocatus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.838AlaAla: 16.838 ± 0.12	1.785AlaCys: 1.785 ± 0.036	5.604AlaAsp: 5.604 ± 0.044	7.656AlaGlu: 7.656 ± 0.069	3.811AlaPhe: 3.811 ± 0.04	10.745AlaGly: 10.745 ± 0.08	2.696AlaHis: 2.696 ± 0.029	4.55AlaIle: 4.55 ± 0.04	2.852AlaLys: 2.852 ± 0.042	15.377AlaLeu: 15.377 ± 0.106	2.519AlaMet: 2.519 ± 0.031	1.936AlaAsn: 1.936 ± 0.03	8.146AlaPro: 8.146 ± 0.07	4.11AlaGln: 4.11 ± 0.04	11.022AlaArg: 11.022 ± 0.084	8.19AlaSer: 8.19 ± 0.059	6.874AlaThr: 6.874 ± 0.053	8.514AlaVal: 8.514 ± 0.063	1.775AlaTrp: 1.775 ± 0.026	2.197AlaTyr: 2.197 ± 0.029	0.0AlaXaa: 0.0 ± 0.0
Cys	1.485CysAla: 1.485 ± 0.026	0.167CysCys: 0.167 ± 0.008	0.822CysAsp: 0.822 ± 0.026	0.68CysGlu: 0.68 ± 0.017	0.326CysPhe: 0.326 ± 0.012	1.223CysGly: 1.223 ± 0.032	0.287CysHis: 0.287 ± 0.01	0.373CysIle: 0.373 ± 0.011	0.243CysLys: 0.243 ± 0.01	0.881CysLeu: 0.881 ± 0.017	0.175CysMet: 0.175 ± 0.008	0.359CysAsn: 0.359 ± 0.016	0.738CysPro: 0.738 ± 0.02	0.343CysGln: 0.343 ± 0.014	0.759CysArg: 0.759 ± 0.015	0.876CysSer: 0.876 ± 0.022	0.714CysThr: 0.714 ± 0.022	0.899CysVal: 0.899 ± 0.021	0.17CysTrp: 0.17 ± 0.011	0.203CysTyr: 0.203 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	7.647AspAla: 7.647 ± 0.053	0.586AspCys: 0.586 ± 0.021	3.635AspAsp: 3.635 ± 0.053	4.078AspGlu: 4.078 ± 0.042	1.643AspPhe: 1.643 ± 0.024	5.868AspGly: 5.868 ± 0.085	1.158AspHis: 1.158 ± 0.021	1.775AspIle: 1.775 ± 0.028	1.117AspLys: 1.117 ± 0.025	5.961AspLeu: 5.961 ± 0.055	0.791AspMet: 0.791 ± 0.017	0.867AspAsn: 0.867 ± 0.029	4.269AspPro: 4.269 ± 0.039	1.454AspGln: 1.454 ± 0.025	4.133AspArg: 4.133 ± 0.036	1.809AspSer: 1.809 ± 0.026	2.464AspThr: 2.464 ± 0.03	4.58AspVal: 4.58 ± 0.035	0.663AspTrp: 0.663 ± 0.016	0.971AspTyr: 0.971 ± 0.019	0.0AspXaa: 0.0 ± 0.0
Glu	8.865GluAla: 8.865 ± 0.067	0.477GluCys: 0.477 ± 0.013	3.009GluAsp: 3.009 ± 0.033	4.098GluGlu: 4.098 ± 0.05	1.291GluPhe: 1.291 ± 0.02	5.886GluGly: 5.886 ± 0.046	1.55GluHis: 1.55 ± 0.024	2.666GluIle: 2.666 ± 0.034	1.674GluLys: 1.674 ± 0.031	6.446GluLeu: 6.446 ± 0.067	1.147GluMet: 1.147 ± 0.021	1.063GluAsn: 1.063 ± 0.019	3.626GluPro: 3.626 ± 0.04	2.473GluGln: 2.473 ± 0.031	6.352GluArg: 6.352 ± 0.064	2.694GluSer: 2.694 ± 0.031	2.947GluThr: 2.947 ± 0.033	5.074GluVal: 5.074 ± 0.044	0.531GluTrp: 0.531 ± 0.013	0.849GluTyr: 0.849 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	3.512PheAla: 3.512 ± 0.03	0.363PheCys: 0.363 ± 0.01	2.223PheAsp: 2.223 ± 0.028	2.068PheGlu: 2.068 ± 0.026	1.127PhePhe: 1.127 ± 0.02	3.006PheGly: 3.006 ± 0.035	0.739PheHis: 0.739 ± 0.018	0.988PheIle: 0.988 ± 0.019	0.634PheLys: 0.634 ± 0.016	2.83PheLeu: 2.83 ± 0.032	0.518PheMet: 0.518 ± 0.013	0.64PheAsn: 0.64 ± 0.017	1.544PhePro: 1.544 ± 0.023	1.003PheGln: 1.003 ± 0.016	2.103PheArg: 2.103 ± 0.026	1.872PheSer: 1.872 ± 0.023	1.736PheThr: 1.736 ± 0.024	2.44PheVal: 2.44 ± 0.031	0.4PheTrp: 0.4 ± 0.012	0.674PheTyr: 0.674 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	11.6GlyAla: 11.6 ± 0.084	1.312GlyCys: 1.312 ± 0.03	5.137GlyAsp: 5.137 ± 0.057	5.832GlyGlu: 5.832 ± 0.054	2.814GlyPhe: 2.814 ± 0.034	9.53GlyGly: 9.53 ± 0.112	1.919GlyHis: 1.919 ± 0.026	3.382GlyIle: 3.382 ± 0.031	2.698GlyLys: 2.698 ± 0.034	7.925GlyLeu: 7.925 ± 0.054	1.999GlyMet: 1.999 ± 0.028	2.026GlyAsn: 2.026 ± 0.039	4.572GlyPro: 4.572 ± 0.047	2.933GlyGln: 2.933 ± 0.038	6.843GlyArg: 6.843 ± 0.053	5.674GlySer: 5.674 ± 0.055	5.326GlyThr: 5.326 ± 0.059	6.961GlyVal: 6.961 ± 0.057	1.281GlyTrp: 1.281 ± 0.023	1.893GlyTyr: 1.893 ± 0.03	0.0GlyXaa: 0.0 ± 0.0
His	2.966HisAla: 2.966 ± 0.037	0.257HisCys: 0.257 ± 0.009	1.301HisAsp: 1.301 ± 0.021	1.38HisGlu: 1.38 ± 0.023	0.706HisPhe: 0.706 ± 0.014	2.091HisGly: 2.091 ± 0.024	0.682HisHis: 0.682 ± 0.017	0.652HisIle: 0.652 ± 0.014	0.357HisLys: 0.357 ± 0.012	2.515HisLeu: 2.515 ± 0.032	0.288HisMet: 0.288 ± 0.009	0.341HisAsn: 0.341 ± 0.01	1.679HisPro: 1.679 ± 0.026	0.651HisGln: 0.651 ± 0.016	1.832HisArg: 1.832 ± 0.025	0.767HisSer: 0.767 ± 0.017	0.975HisThr: 0.975 ± 0.02	1.816HisVal: 1.816 ± 0.025	0.28HisTrp: 0.28 ± 0.009	0.473HisTyr: 0.473 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	5.019IleAla: 5.019 ± 0.043	0.362IleCys: 0.362 ± 0.011	2.69IleAsp: 2.69 ± 0.03	2.764IleGlu: 2.764 ± 0.031	1.002IlePhe: 1.002 ± 0.022	3.179IleGly: 3.179 ± 0.033	0.88IleHis: 0.88 ± 0.017	1.082IleIle: 1.082 ± 0.022	0.816IleLys: 0.816 ± 0.019	3.16IleLeu: 3.16 ± 0.039	0.416IleMet: 0.416 ± 0.013	0.731IleAsn: 0.731 ± 0.017	2.191IlePro: 2.191 ± 0.028	1.138IleGln: 1.138 ± 0.017	2.426IleArg: 2.426 ± 0.029	1.886IleSer: 1.886 ± 0.026	2.084IleThr: 2.084 ± 0.03	2.878IleVal: 2.878 ± 0.036	0.359IleTrp: 0.359 ± 0.012	0.758IleTyr: 0.758 ± 0.017	0.0IleXaa: 0.0 ± 0.0
Lys	2.926LysAla: 2.926 ± 0.044	0.16LysCys: 0.16 ± 0.009	1.216LysAsp: 1.216 ± 0.021	1.451LysGlu: 1.451 ± 0.025	0.564LysPhe: 0.564 ± 0.016	1.97LysGly: 1.97 ± 0.034	0.494LysHis: 0.494 ± 0.014	1.029LysIle: 1.029 ± 0.021	1.009LysLys: 1.009 ± 0.029	2.601LysLeu: 2.601 ± 0.038	0.44LysMet: 0.44 ± 0.013	0.564LysAsn: 0.564 ± 0.014	1.611LysPro: 1.611 ± 0.028	0.801LysGln: 0.801 ± 0.019	1.968LysArg: 1.968 ± 0.033	1.259LysSer: 1.259 ± 0.022	1.312LysThr: 1.312 ± 0.021	1.92LysVal: 1.92 ± 0.032	0.188LysTrp: 0.188 ± 0.008	0.407LysTyr: 0.407 ± 0.014	0.0LysXaa: 0.0 ± 0.0
Leu	13.255LeuAla: 13.255 ± 0.098	1.136LeuCys: 1.136 ± 0.017	6.707LeuAsp: 6.707 ± 0.051	6.239LeuGlu: 6.239 ± 0.061	3.121LeuPhe: 3.121 ± 0.03	9.639LeuGly: 9.639 ± 0.071	2.337LeuHis: 2.337 ± 0.031	3.122LeuIle: 3.122 ± 0.04	2.254LeuLys: 2.254 ± 0.035	11.049LeuLeu: 11.049 ± 0.093	1.469LeuMet: 1.469 ± 0.021	1.675LeuAsn: 1.675 ± 0.026	6.486LeuPro: 6.486 ± 0.058	2.951LeuGln: 2.951 ± 0.033	8.912LeuArg: 8.912 ± 0.07	6.705LeuSer: 6.705 ± 0.049	5.531LeuThr: 5.531 ± 0.046	8.147LeuVal: 8.147 ± 0.057	1.274LeuTrp: 1.274 ± 0.022	1.876LeuTyr: 1.876 ± 0.032	0.0LeuXaa: 0.0 ± 0.0
Met	2.212MetAla: 2.212 ± 0.029	0.133MetCys: 0.133 ± 0.007	0.787MetAsp: 0.787 ± 0.016	0.903MetGlu: 0.903 ± 0.018	0.465MetPhe: 0.465 ± 0.013	1.493MetGly: 1.493 ± 0.021	0.392MetHis: 0.392 ± 0.01	0.687MetIle: 0.687 ± 0.014	0.64MetLys: 0.64 ± 0.017	1.829MetLeu: 1.829 ± 0.026	0.387MetMet: 0.387 ± 0.012	0.504MetAsn: 0.504 ± 0.013	1.201MetPro: 1.201 ± 0.019	0.574MetGln: 0.574 ± 0.015	1.562MetArg: 1.562 ± 0.023	1.342MetSer: 1.342 ± 0.017	1.186MetThr: 1.186 ± 0.021	1.311MetVal: 1.311 ± 0.021	0.149MetTrp: 0.149 ± 0.007	0.263MetTyr: 0.263 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	2.344AsnAla: 2.344 ± 0.031	0.257AsnCys: 0.257 ± 0.016	1.158AsnAsp: 1.158 ± 0.026	1.073AsnGlu: 1.073 ± 0.02	0.578AsnPhe: 0.578 ± 0.014	1.911AsnGly: 1.911 ± 0.04	0.45AsnHis: 0.45 ± 0.012	0.733AsnIle: 0.733 ± 0.018	0.404AsnLys: 0.404 ± 0.013	1.914AsnLeu: 1.914 ± 0.026	0.301AsnMet: 0.301 ± 0.009	0.508AsnAsn: 0.508 ± 0.019	1.493AsnPro: 1.493 ± 0.025	0.644AsnGln: 0.644 ± 0.018	1.254AsnArg: 1.254 ± 0.022	0.836AsnSer: 0.836 ± 0.019	1.022AsnThr: 1.022 ± 0.028	1.498AsnVal: 1.498 ± 0.022	0.214AsnTrp: 0.214 ± 0.009	0.413AsnTyr: 0.413 ± 0.012	0.0AsnXaa: 0.0 ± 0.0
Pro	7.843ProAla: 7.843 ± 0.065	0.608ProCys: 0.608 ± 0.017	3.654ProAsp: 3.654 ± 0.042	4.727ProGlu: 4.727 ± 0.042	1.95ProPhe: 1.95 ± 0.026	5.982ProGly: 5.982 ± 0.054	1.257ProHis: 1.257 ± 0.019	2.023ProIle: 2.023 ± 0.028	1.362ProLys: 1.362 ± 0.025	5.997ProLeu: 5.997 ± 0.058	1.192ProMet: 1.192 ± 0.022	1.173ProAsn: 1.173 ± 0.023	5.645ProPro: 5.645 ± 0.086	1.762ProGln: 1.762 ± 0.022	4.697ProArg: 4.697 ± 0.045	4.75ProSer: 4.75 ± 0.051	3.568ProThr: 3.568 ± 0.041	4.319ProVal: 4.319 ± 0.039	0.853ProTrp: 0.853 ± 0.019	1.079ProTyr: 1.079 ± 0.016	0.0ProXaa: 0.0 ± 0.0
Gln	3.87GlnAla: 3.87 ± 0.038	0.357GlnCys: 0.357 ± 0.013	1.329GlnAsp: 1.329 ± 0.023	1.735GlnGlu: 1.735 ± 0.027	0.79GlnPhe: 0.79 ± 0.015	2.928GlnGly: 2.928 ± 0.035	0.756GlnHis: 0.756 ± 0.017	1.327GlnIle: 1.327 ± 0.02	0.858GlnLys: 0.858 ± 0.022	3.157GlnLeu: 3.157 ± 0.035	0.557GlnMet: 0.557 ± 0.012	0.658GlnAsn: 0.658 ± 0.015	1.934GlnPro: 1.934 ± 0.034	1.219GlnGln: 1.219 ± 0.028	3.011GlnArg: 3.011 ± 0.035	1.521GlnSer: 1.521 ± 0.024	1.459GlnThr: 1.459 ± 0.024	2.513GlnVal: 2.513 ± 0.029	0.34GlnTrp: 0.34 ± 0.01	0.506GlnTyr: 0.506 ± 0.013	0.0GlnXaa: 0.0 ± 0.0
Arg	10.476ArgAla: 10.476 ± 0.086	0.927ArgCys: 0.927 ± 0.019	4.246ArgAsp: 4.246 ± 0.04	5.083ArgGlu: 5.083 ± 0.048	2.955ArgPhe: 2.955 ± 0.031	6.462ArgGly: 6.462 ± 0.055	1.867ArgHis: 1.867 ± 0.025	3.344ArgIle: 3.344 ± 0.036	1.962ArgLys: 1.962 ± 0.03	8.655ArgLeu: 8.655 ± 0.061	1.718ArgMet: 1.718 ± 0.024	1.389ArgAsn: 1.389 ± 0.022	4.545ArgPro: 4.545 ± 0.046	2.237ArgGln: 2.237 ± 0.027	7.211ArgArg: 7.211 ± 0.07	4.619ArgSer: 4.619 ± 0.039	3.976ArgThr: 3.976 ± 0.036	6.276ArgVal: 6.276 ± 0.053	1.356ArgTrp: 1.356 ± 0.025	1.816ArgTyr: 1.816 ± 0.023	0.0ArgXaa: 0.0 ± 0.0
Ser	7.319SerAla: 7.319 ± 0.056	0.784SerCys: 0.784 ± 0.022	2.892SerAsp: 2.892 ± 0.032	3.153SerGlu: 3.153 ± 0.04	2.031SerPhe: 2.031 ± 0.026	5.935SerGly: 5.935 ± 0.051	1.061SerHis: 1.061 ± 0.018	2.145SerIle: 2.145 ± 0.029	1.296SerLys: 1.296 ± 0.026	5.869SerLeu: 5.869 ± 0.051	1.158SerMet: 1.158 ± 0.018	1.195SerAsn: 1.195 ± 0.025	4.342SerPro: 4.342 ± 0.046	1.536SerGln: 1.536 ± 0.024	4.254SerArg: 4.254 ± 0.04	4.333SerSer: 4.333 ± 0.056	3.565SerThr: 3.565 ± 0.037	4.193SerVal: 4.193 ± 0.035	0.822SerTrp: 0.822 ± 0.017	1.112SerTyr: 1.112 ± 0.02	0.0SerXaa: 0.0 ± 0.0
Thr	6.206ThrAla: 6.206 ± 0.051	0.83ThrCys: 0.83 ± 0.026	2.548ThrAsp: 2.548 ± 0.034	2.754ThrGlu: 2.754 ± 0.028	1.816ThrPhe: 1.816 ± 0.025	4.958ThrGly: 4.958 ± 0.048	1.106ThrHis: 1.106 ± 0.019	1.946ThrIle: 1.946 ± 0.028	1.137ThrLys: 1.137 ± 0.022	6.109ThrLeu: 6.109 ± 0.048	0.951ThrMet: 0.951 ± 0.017	1.048ThrAsn: 1.048 ± 0.02	4.364ThrPro: 4.364 ± 0.044	1.585ThrGln: 1.585 ± 0.02	3.988ThrArg: 3.988 ± 0.037	3.676ThrSer: 3.676 ± 0.04	3.579ThrThr: 3.579 ± 0.052	4.024ThrVal: 4.024 ± 0.04	0.855ThrTrp: 0.855 ± 0.019	1.163ThrTyr: 1.163 ± 0.022	0.0ThrXaa: 0.0 ± 0.0
Val	9.404ValAla: 9.404 ± 0.064	0.884ValCys: 0.884 ± 0.022	4.665ValAsp: 4.665 ± 0.041	5.101ValGlu: 5.101 ± 0.047	2.311ValPhe: 2.311 ± 0.026	6.107ValGly: 6.107 ± 0.057	1.668ValHis: 1.668 ± 0.022	2.862ValIle: 2.862 ± 0.033	1.8ValLys: 1.8 ± 0.027	8.061ValLeu: 8.061 ± 0.06	1.341ValMet: 1.341 ± 0.023	1.522ValAsn: 1.522 ± 0.025	4.397ValPro: 4.397 ± 0.039	2.338ValGln: 2.338 ± 0.03	6.092ValArg: 6.092 ± 0.05	4.386ValSer: 4.386 ± 0.037	4.538ValThr: 4.538 ± 0.04	6.661ValVal: 6.661 ± 0.062	0.897ValTrp: 0.897 ± 0.02	1.416ValTyr: 1.416 ± 0.021	0.0ValXaa: 0.0 ± 0.0
Trp	1.253TrpAla: 1.253 ± 0.021	0.129TrpCys: 0.129 ± 0.007	0.65TrpAsp: 0.65 ± 0.014	0.694TrpGlu: 0.694 ± 0.015	0.43TrpPhe: 0.43 ± 0.012	1.022TrpGly: 1.022 ± 0.021	0.286TrpHis: 0.286 ± 0.01	0.607TrpIle: 0.607 ± 0.014	0.369TrpLys: 0.369 ± 0.012	1.533TrpLeu: 1.533 ± 0.023	0.32TrpMet: 0.32 ± 0.01	0.375TrpAsn: 0.375 ± 0.012	0.643TrpPro: 0.643 ± 0.016	0.443TrpGln: 0.443 ± 0.012	1.025TrpArg: 1.025 ± 0.017	0.983TrpSer: 0.983 ± 0.022	0.807TrpThr: 0.807 ± 0.019	0.908TrpVal: 0.908 ± 0.019	0.203TrpTrp: 0.203 ± 0.009	0.248TrpTyr: 0.248 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.157TyrAla: 2.157 ± 0.028	0.21TyrCys: 0.21 ± 0.009	1.2TyrAsp: 1.2 ± 0.023	1.252TyrGlu: 1.252 ± 0.021	0.689TyrPhe: 0.689 ± 0.013	1.724TyrGly: 1.724 ± 0.025	0.421TyrHis: 0.421 ± 0.012	0.529TyrIle: 0.529 ± 0.012	0.405TyrLys: 0.405 ± 0.013	2.017TyrLeu: 2.017 ± 0.026	0.332TyrMet: 0.332 ± 0.01	0.429TyrAsn: 0.429 ± 0.012	1.018TyrPro: 1.018 ± 0.018	0.63TyrGln: 0.63 ± 0.014	1.678TyrArg: 1.678 ± 0.027	0.816TyrSer: 0.816 ± 0.018	0.981TyrThr: 0.981 ± 0.018	1.516TyrVal: 1.516 ± 0.025	0.314TyrTrp: 0.314 ± 0.012	0.472TyrTyr: 0.472 ± 0.013	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 8327 proteins (3359666 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---