Amino acid dipepetide frequency for Gyrovirus 4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.282AlaAla: 5.282 ± 0.391
3.521AlaCys: 3.521 ± 3.376
3.521AlaAsp: 3.521 ± 2.079
8.803AlaGlu: 8.803 ± 0.257
7.042AlaPhe: 7.042 ± 4.158
1.761AlaGly: 1.761 ± 1.688
0.0AlaHis: 0.0 ± 0.0
0.0AlaIle: 0.0 ± 0.0
1.761AlaLys: 1.761 ± 1.04
3.521AlaLeu: 3.521 ± 0.648
0.0AlaMet: 0.0 ± 0.0
1.761AlaAsn: 1.761 ± 1.04
1.761AlaPro: 1.761 ± 1.688
1.761AlaGln: 1.761 ± 1.04
5.282AlaArg: 5.282 ± 5.063
1.761AlaSer: 1.761 ± 1.04
3.521AlaThr: 3.521 ± 2.079
3.521AlaVal: 3.521 ± 0.648
3.521AlaTrp: 3.521 ± 2.079
3.521AlaTyr: 3.521 ± 2.079
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
1.761CysPhe: 1.761 ± 1.688
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.761CysPro: 1.761 ± 1.688
0.0CysGln: 0.0 ± 0.0
5.282CysArg: 5.282 ± 5.063
0.0CysSer: 0.0 ± 0.0
1.761CysThr: 1.761 ± 1.688
0.0CysVal: 0.0 ± 0.0
1.761CysTrp: 1.761 ± 1.688
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
7.042AspAla: 7.042 ± 6.751
0.0AspCys: 0.0 ± 0.0
0.0AspAsp: 0.0 ± 0.0
0.0AspGlu: 0.0 ± 0.0
1.761AspPhe: 1.761 ± 1.04
1.761AspGly: 1.761 ± 1.688
1.761AspHis: 1.761 ± 1.688
1.761AspIle: 1.761 ± 1.04
0.0AspLys: 0.0 ± 0.0
5.282AspLeu: 5.282 ± 2.336
0.0AspMet: 0.0 ± 0.0
0.0AspAsn: 0.0 ± 0.0
5.282AspPro: 5.282 ± 2.336
1.761AspGln: 1.761 ± 1.04
1.761AspArg: 1.761 ± 1.688
8.803AspSer: 8.803 ± 2.984
1.761AspThr: 1.761 ± 1.04
3.521AspVal: 3.521 ± 2.079
1.761AspTrp: 1.761 ± 1.04
1.761AspTyr: 1.761 ± 1.688
0.0AspXaa: 0.0 ± 0.0
Glu
0.0GluAla: 0.0 ± 0.0
1.761GluCys: 1.761 ± 1.688
1.761GluAsp: 1.761 ± 1.688
1.761GluGlu: 1.761 ± 1.688
5.282GluPhe: 5.282 ± 0.391
7.042GluGly: 7.042 ± 6.751
0.0GluHis: 0.0 ± 0.0
1.761GluIle: 1.761 ± 1.688
0.0GluLys: 0.0 ± 0.0
3.521GluLeu: 3.521 ± 2.079
0.0GluMet: 0.0 ± 0.0
1.761GluAsn: 1.761 ± 1.04
3.521GluPro: 3.521 ± 0.648
0.0GluGln: 0.0 ± 0.0
0.0GluArg: 0.0 ± 0.0
3.521GluSer: 3.521 ± 3.376
5.282GluThr: 5.282 ± 0.391
3.521GluVal: 3.521 ± 3.376
3.521GluTrp: 3.521 ± 3.376
1.761GluTyr: 1.761 ± 1.04
0.0GluXaa: 0.0 ± 0.0
Phe
3.521PheAla: 3.521 ± 2.079
0.0PheCys: 0.0 ± 0.0
0.0PheAsp: 0.0 ± 0.0
1.761PheGlu: 1.761 ± 1.04
1.761PhePhe: 1.761 ± 1.04
3.521PheGly: 3.521 ± 2.079
0.0PheHis: 0.0 ± 0.0
0.0PheIle: 0.0 ± 0.0
5.282PheLys: 5.282 ± 0.391
7.042PheLeu: 7.042 ± 1.296
0.0PheMet: 0.0 ± 0.0
5.282PheAsn: 5.282 ± 0.391
1.761PhePro: 1.761 ± 1.04
5.282PheGln: 5.282 ± 0.391
10.563PheArg: 10.563 ± 0.783
7.042PheSer: 7.042 ± 1.431
5.282PheThr: 5.282 ± 0.391
3.521PheVal: 3.521 ± 0.648
0.0PheTrp: 0.0 ± 0.0
1.761PheTyr: 1.761 ± 1.04
0.0PheXaa: 0.0 ± 0.0
Gly
5.282GlyAla: 5.282 ± 2.336
0.0GlyCys: 0.0 ± 0.0
5.282GlyAsp: 5.282 ± 5.063
3.521GlyGlu: 3.521 ± 0.648
0.0GlyPhe: 0.0 ± 0.0
17.606GlyGly: 17.606 ± 11.423
0.0GlyHis: 0.0 ± 0.0
5.282GlyIle: 5.282 ± 5.063
3.521GlyLys: 3.521 ± 0.648
1.761GlyLeu: 1.761 ± 1.04
0.0GlyMet: 0.0 ± 0.0
3.521GlyAsn: 3.521 ± 0.648
3.521GlyPro: 3.521 ± 0.648
3.521GlyGln: 3.521 ± 2.079
5.282GlyArg: 5.282 ± 3.119
3.521GlySer: 3.521 ± 0.648
12.324GlyThr: 12.324 ± 3.633
5.282GlyVal: 5.282 ± 2.336
3.521GlyTrp: 3.521 ± 2.079
1.761GlyTyr: 1.761 ± 1.04
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
1.761HisPhe: 1.761 ± 1.04
0.0HisGly: 0.0 ± 0.0
1.761HisHis: 1.761 ± 1.04
1.761HisIle: 1.761 ± 1.04
0.0HisLys: 0.0 ± 0.0
1.761HisLeu: 1.761 ± 1.04
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
3.521HisPro: 3.521 ± 2.079
1.761HisGln: 1.761 ± 1.04
3.521HisArg: 3.521 ± 0.648
3.521HisSer: 3.521 ± 0.648
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
1.761HisTrp: 1.761 ± 1.688
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.761IleAla: 1.761 ± 1.688
0.0IleCys: 0.0 ± 0.0
1.761IleAsp: 1.761 ± 1.688
3.521IleGlu: 3.521 ± 0.648
1.761IlePhe: 1.761 ± 1.04
1.761IleGly: 1.761 ± 1.688
0.0IleHis: 0.0 ± 0.0
0.0IleIle: 0.0 ± 0.0
1.761IleLys: 1.761 ± 1.04
3.521IleLeu: 3.521 ± 0.648
0.0IleMet: 0.0 ± 0.0
1.761IleAsn: 1.761 ± 1.04
0.0IlePro: 0.0 ± 0.0
1.761IleGln: 1.761 ± 1.04
1.761IleArg: 1.761 ± 1.04
3.521IleSer: 3.521 ± 0.648
0.0IleThr: 0.0 ± 0.0
1.761IleVal: 1.761 ± 1.04
0.0IleTrp: 0.0 ± 0.0
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
1.761LysAla: 1.761 ± 1.04
0.0LysCys: 0.0 ± 0.0
0.0LysAsp: 0.0 ± 0.0
1.761LysGlu: 1.761 ± 1.688
3.521LysPhe: 3.521 ± 2.079
1.761LysGly: 1.761 ± 1.04
0.0LysHis: 0.0 ± 0.0
0.0LysIle: 0.0 ± 0.0
1.761LysLys: 1.761 ± 1.688
1.761LysLeu: 1.761 ± 1.688
0.0LysMet: 0.0 ± 0.0
0.0LysAsn: 0.0 ± 0.0
3.521LysPro: 3.521 ± 3.376
1.761LysGln: 1.761 ± 1.688
8.803LysArg: 8.803 ± 2.984
1.761LysSer: 1.761 ± 1.04
7.042LysThr: 7.042 ± 4.158
5.282LysVal: 5.282 ± 3.119
0.0LysTrp: 0.0 ± 0.0
1.761LysTyr: 1.761 ± 1.04
0.0LysXaa: 0.0 ± 0.0
Leu
8.803LeuAla: 8.803 ± 5.198
0.0LeuCys: 0.0 ± 0.0
3.521LeuAsp: 3.521 ± 0.648
5.282LeuGlu: 5.282 ± 5.063
7.042LeuPhe: 7.042 ± 4.158
0.0LeuGly: 0.0 ± 0.0
0.0LeuHis: 0.0 ± 0.0
0.0LeuIle: 0.0 ± 0.0
3.521LeuLys: 3.521 ± 0.648
12.324LeuLeu: 12.324 ± 0.905
0.0LeuMet: 0.0 ± 0.0
3.521LeuAsn: 3.521 ± 2.079
3.521LeuPro: 3.521 ± 2.079
1.761LeuGln: 1.761 ± 1.04
5.282LeuArg: 5.282 ± 2.336
8.803LeuSer: 8.803 ± 0.257
7.042LeuThr: 7.042 ± 1.431
0.0LeuVal: 0.0 ± 0.0
0.0LeuTrp: 0.0 ± 0.0
1.761LeuTyr: 1.761 ± 1.04
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
3.521MetGly: 3.521 ± 3.376
1.761MetHis: 1.761 ± 1.04
0.0MetIle: 0.0 ± 0.0
1.761MetLys: 1.761 ± 1.04
0.0MetLeu: 0.0 ± 0.0
1.761MetMet: 1.761 ± 1.045
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
3.521MetArg: 3.521 ± 0.648
0.0MetSer: 0.0 ± 0.0
0.0MetThr: 0.0 ± 0.0
1.761MetVal: 1.761 ± 1.04
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.521AsnAla: 3.521 ± 2.079
0.0AsnCys: 0.0 ± 0.0
1.761AsnAsp: 1.761 ± 1.04
1.761AsnGlu: 1.761 ± 1.04
3.521AsnPhe: 3.521 ± 0.648
0.0AsnGly: 0.0 ± 0.0
3.521AsnHis: 3.521 ± 0.648
1.761AsnIle: 1.761 ± 1.04
1.761AsnLys: 1.761 ± 1.04
1.761AsnLeu: 1.761 ± 1.04
0.0AsnMet: 0.0 ± 0.0
1.761AsnAsn: 1.761 ± 1.04
0.0AsnPro: 0.0 ± 0.0
1.761AsnGln: 1.761 ± 1.04
1.761AsnArg: 1.761 ± 1.04
1.761AsnSer: 1.761 ± 1.04
5.282AsnThr: 5.282 ± 3.119
0.0AsnVal: 0.0 ± 0.0
1.761AsnTrp: 1.761 ± 1.04
3.521AsnTyr: 3.521 ± 0.648
0.0AsnXaa: 0.0 ± 0.0
Pro
1.761ProAla: 1.761 ± 1.688
0.0ProCys: 0.0 ± 0.0
5.282ProAsp: 5.282 ± 0.391
0.0ProGlu: 0.0 ± 0.0
1.761ProPhe: 1.761 ± 1.688
8.803ProGly: 8.803 ± 0.257
0.0ProHis: 0.0 ± 0.0
1.761ProIle: 1.761 ± 1.688
5.282ProLys: 5.282 ± 2.336
3.521ProLeu: 3.521 ± 2.079
0.0ProMet: 0.0 ± 0.0
0.0ProAsn: 0.0 ± 0.0
1.761ProPro: 1.761 ± 1.688
1.761ProGln: 1.761 ± 1.688
3.521ProArg: 3.521 ± 3.376
3.521ProSer: 3.521 ± 2.079
3.521ProThr: 3.521 ± 2.079
1.761ProVal: 1.761 ± 1.688
3.521ProTrp: 3.521 ± 2.079
3.521ProTyr: 3.521 ± 2.079
0.0ProXaa: 0.0 ± 0.0
Gln
1.761GlnAla: 1.761 ± 1.04
0.0GlnCys: 0.0 ± 0.0
1.761GlnAsp: 1.761 ± 1.04
0.0GlnGlu: 0.0 ± 0.0
0.0GlnPhe: 0.0 ± 0.0
1.761GlnGly: 1.761 ± 1.04
3.521GlnHis: 3.521 ± 2.079
0.0GlnIle: 0.0 ± 0.0
1.761GlnLys: 1.761 ± 1.04
7.042GlnLeu: 7.042 ± 1.431
0.0GlnMet: 0.0 ± 0.0
1.761GlnAsn: 1.761 ± 1.04
0.0GlnPro: 0.0 ± 0.0
1.761GlnGln: 1.761 ± 1.04
1.761GlnArg: 1.761 ± 1.04
1.761GlnSer: 1.761 ± 1.04
1.761GlnThr: 1.761 ± 1.688
5.282GlnVal: 5.282 ± 0.391
5.282GlnTrp: 5.282 ± 0.391
3.521GlnTyr: 3.521 ± 2.079
0.0GlnXaa: 0.0 ± 0.0
Arg
3.521ArgAla: 3.521 ± 0.648
1.761ArgCys: 1.761 ± 1.688
1.761ArgAsp: 1.761 ± 1.688
3.521ArgGlu: 3.521 ± 3.376
7.042ArgPhe: 7.042 ± 1.296
8.803ArgGly: 8.803 ± 0.257
3.521ArgHis: 3.521 ± 2.079
1.761ArgIle: 1.761 ± 1.04
7.042ArgLys: 7.042 ± 1.296
3.521ArgLeu: 3.521 ± 0.648
5.282ArgMet: 5.282 ± 2.336
3.521ArgAsn: 3.521 ± 0.648
7.042ArgPro: 7.042 ± 4.158
0.0ArgGln: 0.0 ± 0.0
15.845ArgArg: 15.845 ± 3.901
7.042ArgSer: 7.042 ± 1.431
0.0ArgThr: 0.0 ± 0.0
10.563ArgVal: 10.563 ± 1.945
3.521ArgTrp: 3.521 ± 2.079
1.761ArgTyr: 1.761 ± 1.04
0.0ArgXaa: 0.0 ± 0.0
Ser
7.042SerAla: 7.042 ± 1.431
0.0SerCys: 0.0 ± 0.0
7.042SerAsp: 7.042 ± 4.024
1.761SerGlu: 1.761 ± 1.04
8.803SerPhe: 8.803 ± 2.984
10.563SerGly: 10.563 ± 0.783
3.521SerHis: 3.521 ± 0.648
5.282SerIle: 5.282 ± 0.391
1.761SerLys: 1.761 ± 1.04
5.282SerLeu: 5.282 ± 3.119
3.521SerMet: 3.521 ± 2.079
1.761SerAsn: 1.761 ± 1.04
5.282SerPro: 5.282 ± 0.391
3.521SerGln: 3.521 ± 2.079
1.761SerArg: 1.761 ± 1.688
3.521SerSer: 3.521 ± 3.376
7.042SerThr: 7.042 ± 6.751
5.282SerVal: 5.282 ± 0.391
0.0SerTrp: 0.0 ± 0.0
3.521SerTyr: 3.521 ± 2.079
0.0SerXaa: 0.0 ± 0.0
Thr
3.521ThrAla: 3.521 ± 0.648
0.0ThrCys: 0.0 ± 0.0
7.042ThrAsp: 7.042 ± 1.431
7.042ThrGlu: 7.042 ± 4.024
0.0ThrPhe: 0.0 ± 0.0
7.042ThrGly: 7.042 ± 1.296
0.0ThrHis: 0.0 ± 0.0
0.0ThrIle: 0.0 ± 0.0
0.0ThrLys: 0.0 ± 0.0
3.521ThrLeu: 3.521 ± 2.079
0.0ThrMet: 0.0 ± 0.804
3.521ThrAsn: 3.521 ± 2.079
7.042ThrPro: 7.042 ± 1.296
3.521ThrGln: 3.521 ± 2.079
3.521ThrArg: 3.521 ± 2.079
12.324ThrSer: 12.324 ± 0.905
0.0ThrThr: 0.0 ± 0.0
3.521ThrVal: 3.521 ± 0.648
1.761ThrTrp: 1.761 ± 1.04
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
0.0ValAla: 0.0 ± 0.0
5.282ValCys: 5.282 ± 5.063
3.521ValAsp: 3.521 ± 3.376
5.282ValGlu: 5.282 ± 5.063
7.042ValPhe: 7.042 ± 4.158
1.761ValGly: 1.761 ± 1.688
0.0ValHis: 0.0 ± 0.0
1.761ValIle: 1.761 ± 1.04
1.761ValLys: 1.761 ± 1.04
3.521ValLeu: 3.521 ± 2.079
0.0ValMet: 0.0 ± 0.0
3.521ValAsn: 3.521 ± 2.079
1.761ValPro: 1.761 ± 1.688
5.282ValGln: 5.282 ± 0.391
8.803ValArg: 8.803 ± 5.198
8.803ValSer: 8.803 ± 0.257
1.761ValThr: 1.761 ± 1.04
3.521ValVal: 3.521 ± 2.079
0.0ValTrp: 0.0 ± 0.0
1.761ValTyr: 1.761 ± 1.04
0.0ValXaa: 0.0 ± 0.0
Trp
3.521TrpAla: 3.521 ± 2.079
0.0TrpCys: 0.0 ± 0.0
1.761TrpAsp: 1.761 ± 1.688
0.0TrpGlu: 0.0 ± 0.0
1.761TrpPhe: 1.761 ± 1.688
3.521TrpGly: 3.521 ± 2.079
1.761TrpHis: 1.761 ± 1.04
0.0TrpIle: 0.0 ± 0.0
3.521TrpLys: 3.521 ± 0.648
1.761TrpLeu: 1.761 ± 1.688
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
3.521TrpGln: 3.521 ± 2.079
3.521TrpArg: 3.521 ± 2.079
3.521TrpSer: 3.521 ± 0.648
1.761TrpThr: 1.761 ± 1.04
1.761TrpVal: 1.761 ± 1.04
1.761TrpTrp: 1.761 ± 1.04
1.761TrpTyr: 1.761 ± 1.04
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.521TyrAla: 3.521 ± 2.079
0.0TyrCys: 0.0 ± 0.0
0.0TyrAsp: 0.0 ± 0.0
0.0TyrGlu: 0.0 ± 0.0
1.761TyrPhe: 1.761 ± 1.04
3.521TyrGly: 3.521 ± 0.648
0.0TyrHis: 0.0 ± 0.0
3.521TyrIle: 3.521 ± 2.079
0.0TyrLys: 0.0 ± 0.0
1.761TyrLeu: 1.761 ± 1.04
1.761TyrMet: 1.761 ± 1.688
3.521TyrAsn: 3.521 ± 2.079
0.0TyrPro: 0.0 ± 0.0
0.0TyrGln: 0.0 ± 0.0
5.282TyrArg: 5.282 ± 3.119
1.761TyrSer: 1.761 ± 1.04
0.0TyrThr: 0.0 ± 0.0
5.282TyrVal: 5.282 ± 3.119
1.761TyrTrp: 1.761 ± 1.04
1.761TyrTyr: 1.761 ± 1.04
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (569 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski