Trypanosoma rangeli

Taxonomy: cellular organisms; Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina; Trypanosomatida; Trypanosomatidae; Trypanosoma; Herpetosoma

Average proteome isoelectric point is 6.86

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 10070 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A422NHB0|A0A422NHB0_TRYRA Uncharacterized protein OS=Trypanosoma rangeli OX=5698 GN=TraAM80_04960 PE=4 SV=1
MM1 pKa = 7.18FAVDD5 pKa = 5.44LLDD8 pKa = 4.35ALAEE12 pKa = 4.01AAVILLFDD20 pKa = 4.1WTPTSACGDD29 pKa = 3.69EE30 pKa = 5.45DD31 pKa = 4.34NDD33 pKa = 4.43GEE35 pKa = 4.32IGSEE39 pKa = 3.93RR40 pKa = 11.84FTGLNSWSSLDD51 pKa = 3.38SCFPRR56 pKa = 11.84SQMNTTLSANNASLTASRR74 pKa = 11.84TLSLDD79 pKa = 3.16CSSFLQVAAEE89 pKa = 4.75EE90 pKa = 4.46IQTTPSEE97 pKa = 4.17QLVGSQDD104 pKa = 3.45HH105 pKa = 5.82YY106 pKa = 11.38CWTNEE111 pKa = 3.57YY112 pKa = 10.3EE113 pKa = 4.43YY114 pKa = 10.76FNSSSSTPSSWAVPVRR130 pKa = 11.84SLEE133 pKa = 4.04QKK135 pKa = 10.44

Molecular weight: 14.77 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A422NW00|A0A422NW00_TRYRA V-type proton ATPase proteolipid subunit OS=Trypanosoma rangeli OX=5698 GN=TraAM80_02012 PE=3 SV=1
MM1 pKa = 7.77PSTVARR7 pKa = 11.84EE8 pKa = 3.91RR9 pKa = 11.84NKK11 pKa = 10.56AAVRR15 pKa = 11.84RR16 pKa = 11.84LFARR20 pKa = 11.84DD21 pKa = 3.87HH22 pKa = 6.42VPSPAPWKK30 pKa = 10.4CHH32 pKa = 5.01TVHH35 pKa = 6.73CADD38 pKa = 3.42GTLPPGMHH46 pKa = 7.24LSKK49 pKa = 10.56QCEE52 pKa = 3.97LAHH55 pKa = 5.37EE56 pKa = 4.61VGRR59 pKa = 11.84GTAAAVAVAAAAATSSPHH77 pKa = 5.74SRR79 pKa = 11.84AVDD82 pKa = 3.47YY83 pKa = 10.96GNPFCSCYY91 pKa = 10.96SMNRR95 pKa = 11.84KK96 pKa = 8.53IARR99 pKa = 11.84HH100 pKa = 4.77EE101 pKa = 4.05WATSRR106 pKa = 11.84AEE108 pKa = 3.93KK109 pKa = 10.65GKK111 pKa = 10.09LQGGPLNPHH120 pKa = 5.91KK121 pKa = 10.45SARR124 pKa = 11.84EE125 pKa = 3.29RR126 pKa = 11.84RR127 pKa = 11.84AAIEE131 pKa = 3.94HH132 pKa = 6.52EE133 pKa = 4.28EE134 pKa = 4.21AILRR138 pKa = 11.84YY139 pKa = 8.86EE140 pKa = 3.81LSIPRR145 pKa = 11.84RR146 pKa = 11.84RR147 pKa = 11.84VAGHH151 pKa = 7.44LLHH154 pKa = 6.78LTAAQLSTSQPMPRR168 pKa = 11.84ARR170 pKa = 11.84TMDD173 pKa = 3.48RR174 pKa = 11.84LVEE177 pKa = 3.98HH178 pKa = 7.24RR179 pKa = 11.84KK180 pKa = 10.04GCWVLHH186 pKa = 5.23NPYY189 pKa = 9.85RR190 pKa = 11.84QQLLRR195 pKa = 11.84GEE197 pKa = 4.25PVMTRR202 pKa = 11.84IMHH205 pKa = 5.98GEE207 pKa = 3.97FYY209 pKa = 10.61EE210 pKa = 4.18PQRR213 pKa = 11.84NEE215 pKa = 3.45QNTINFSQANKK226 pKa = 9.79RR227 pKa = 11.84HH228 pKa = 4.85VQVASSINHH237 pKa = 6.13AMHH240 pKa = 6.98SSRR243 pKa = 11.84NTRR246 pKa = 3.1

Molecular weight: 27.65 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

10070

0

10070

4520539

93

5642

448.9

49.76

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

9.199 ± 0.026

2.138 ± 0.012

4.771 ± 0.015

6.859 ± 0.024

3.636 ± 0.017

6.549 ± 0.02

2.672 ± 0.011

3.6 ± 0.017

4.123 ± 0.021

9.986 ± 0.024

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.471 ± 0.009

3.223 ± 0.013

4.995 ± 0.019

3.996 ± 0.016

7.276 ± 0.024

7.526 ± 0.024

5.691 ± 0.017

7.577 ± 0.018

1.225 ± 0.008

2.427 ± 0.012
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski