Amino acid dipepetide frequency for Wenzhou shrimp virus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.131AlaAla: 9.131 ± 1.308
0.945AlaCys: 0.945 ± 0.427
3.463AlaAsp: 3.463 ± 0.913
6.297AlaGlu: 6.297 ± 0.673
1.889AlaPhe: 1.889 ± 0.545
4.093AlaGly: 4.093 ± 1.485
3.149AlaHis: 3.149 ± 0.803
2.834AlaIle: 2.834 ± 1.473
3.778AlaLys: 3.778 ± 1.539
5.668AlaLeu: 5.668 ± 1.504
2.519AlaMet: 2.519 ± 0.561
2.834AlaAsn: 2.834 ± 0.979
5.668AlaPro: 5.668 ± 1.51
3.778AlaGln: 3.778 ± 1.304
6.297AlaArg: 6.297 ± 1.177
4.723AlaSer: 4.723 ± 0.76
6.297AlaThr: 6.297 ± 2.435
6.612AlaVal: 6.612 ± 0.88
1.259AlaTrp: 1.259 ± 0.655
2.204AlaTyr: 2.204 ± 0.805
0.0AlaXaa: 0.0 ± 0.0
Cys
0.63CysAla: 0.63 ± 0.494
0.945CysCys: 0.945 ± 0.491
2.519CysAsp: 2.519 ± 0.581
0.63CysGlu: 0.63 ± 0.327
1.574CysPhe: 1.574 ± 0.47
1.259CysGly: 1.259 ± 0.655
0.0CysHis: 0.0 ± 0.0
0.63CysIle: 0.63 ± 0.552
1.574CysLys: 1.574 ± 0.637
0.945CysLeu: 0.945 ± 0.491
0.315CysMet: 0.315 ± 0.164
0.315CysAsn: 0.315 ± 0.164
0.945CysPro: 0.945 ± 0.345
0.945CysGln: 0.945 ± 0.491
0.315CysArg: 0.315 ± 0.517
1.574CysSer: 1.574 ± 0.64
0.315CysThr: 0.315 ± 0.164
1.574CysVal: 1.574 ± 0.429
0.0CysTrp: 0.0 ± 0.0
0.945CysTyr: 0.945 ± 0.491
0.0CysXaa: 0.0 ± 0.0
Asp
4.093AspAla: 4.093 ± 1.479
0.63AspCys: 0.63 ± 0.327
5.353AspAsp: 5.353 ± 2.661
7.242AspGlu: 7.242 ± 1.927
2.519AspPhe: 2.519 ± 1.603
5.668AspGly: 5.668 ± 1.908
0.945AspHis: 0.945 ± 0.491
3.778AspIle: 3.778 ± 1.585
2.519AspLys: 2.519 ± 0.827
4.723AspLeu: 4.723 ± 0.455
0.945AspMet: 0.945 ± 1.066
2.834AspAsn: 2.834 ± 0.769
4.408AspPro: 4.408 ± 1.586
1.259AspGln: 1.259 ± 0.587
2.834AspArg: 2.834 ± 0.979
3.463AspSer: 3.463 ± 1.768
2.834AspThr: 2.834 ± 0.769
7.242AspVal: 7.242 ± 1.863
1.259AspTrp: 1.259 ± 0.418
1.889AspTyr: 1.889 ± 0.486
0.0AspXaa: 0.0 ± 0.0
Glu
4.093GluAla: 4.093 ± 0.806
0.63GluCys: 0.63 ± 0.327
3.149GluAsp: 3.149 ± 1.054
6.927GluGlu: 6.927 ± 1.439
3.463GluPhe: 3.463 ± 0.393
4.093GluGly: 4.093 ± 0.845
2.204GluHis: 2.204 ± 0.86
5.982GluIle: 5.982 ± 1.013
4.408GluLys: 4.408 ± 1.063
5.353GluLeu: 5.353 ± 1.739
1.259GluMet: 1.259 ± 0.701
1.889GluAsn: 1.889 ± 0.574
4.093GluPro: 4.093 ± 0.882
4.093GluGln: 4.093 ± 1.149
5.353GluArg: 5.353 ± 1.331
2.519GluSer: 2.519 ± 0.952
3.149GluThr: 3.149 ± 0.719
3.149GluVal: 3.149 ± 1.245
0.63GluTrp: 0.63 ± 0.932
3.149GluTyr: 3.149 ± 1.398
0.0GluXaa: 0.0 ± 0.0
Phe
3.463PheAla: 3.463 ± 0.868
1.574PheCys: 1.574 ± 0.818
4.093PheAsp: 4.093 ± 1.736
2.204PheGlu: 2.204 ± 0.688
1.889PhePhe: 1.889 ± 0.566
2.834PheGly: 2.834 ± 0.634
0.945PheHis: 0.945 ± 0.534
0.945PheIle: 0.945 ± 0.491
4.093PheLys: 4.093 ± 0.882
3.463PheLeu: 3.463 ± 0.986
1.259PheMet: 1.259 ± 0.711
4.093PheAsn: 4.093 ± 1.682
1.574PhePro: 1.574 ± 0.998
1.889PheGln: 1.889 ± 0.727
0.63PheArg: 0.63 ± 0.85
2.204PheSer: 2.204 ± 0.679
0.945PheThr: 0.945 ± 0.427
2.834PheVal: 2.834 ± 1.848
0.0PheTrp: 0.0 ± 0.0
1.574PheTyr: 1.574 ± 1.169
0.0PheXaa: 0.0 ± 0.0
Gly
5.038GlyAla: 5.038 ± 2.092
1.574GlyCys: 1.574 ± 0.909
5.038GlyAsp: 5.038 ± 1.2
7.242GlyGlu: 7.242 ± 0.81
1.889GlyPhe: 1.889 ± 0.737
3.149GlyGly: 3.149 ± 0.719
0.945GlyHis: 0.945 ± 0.427
3.463GlyIle: 3.463 ± 0.834
3.149GlyLys: 3.149 ± 1.12
2.519GlyLeu: 2.519 ± 0.825
1.259GlyMet: 1.259 ± 0.655
2.519GlyAsn: 2.519 ± 1.908
1.574GlyPro: 1.574 ± 0.636
2.519GlyGln: 2.519 ± 0.404
2.834GlyArg: 2.834 ± 0.659
4.093GlySer: 4.093 ± 1.677
2.834GlyThr: 2.834 ± 0.762
2.834GlyVal: 2.834 ± 1.099
0.315GlyTrp: 0.315 ± 0.164
1.889GlyTyr: 1.889 ± 1.067
0.0GlyXaa: 0.0 ± 0.0
His
1.259HisAla: 1.259 ± 0.655
0.63HisCys: 0.63 ± 0.327
1.259HisAsp: 1.259 ± 0.564
2.204HisGlu: 2.204 ± 1.241
1.574HisPhe: 1.574 ± 0.636
1.259HisGly: 1.259 ± 0.418
1.574HisHis: 1.574 ± 0.47
1.889HisIle: 1.889 ± 0.855
0.945HisLys: 0.945 ± 0.491
3.778HisLeu: 3.778 ± 1.056
0.63HisMet: 0.63 ± 0.552
0.945HisAsn: 0.945 ± 0.491
1.259HisPro: 1.259 ± 1.105
0.945HisGln: 0.945 ± 0.345
0.945HisArg: 0.945 ± 0.345
1.574HisSer: 1.574 ± 0.429
1.889HisThr: 1.889 ± 0.982
1.889HisVal: 1.889 ± 0.982
0.945HisTrp: 0.945 ± 0.491
0.63HisTyr: 0.63 ± 0.552
0.0HisXaa: 0.0 ± 0.0
Ile
5.353IleAla: 5.353 ± 0.886
0.945IleCys: 0.945 ± 0.577
2.204IleAsp: 2.204 ± 1.777
5.982IleGlu: 5.982 ± 1.688
1.259IlePhe: 1.259 ± 1.105
1.574IleGly: 1.574 ± 0.818
0.945IleHis: 0.945 ± 0.577
2.834IleIle: 2.834 ± 0.697
2.519IleLys: 2.519 ± 0.701
3.149IleLeu: 3.149 ± 1.054
0.63IleMet: 0.63 ± 0.327
2.204IleAsn: 2.204 ± 0.688
4.408IlePro: 4.408 ± 1.104
1.889IleGln: 1.889 ± 0.408
3.149IleArg: 3.149 ± 1.106
4.093IleSer: 4.093 ± 0.845
4.093IleThr: 4.093 ± 2.194
5.668IleVal: 5.668 ± 0.984
0.0IleTrp: 0.0 ± 0.0
2.519IleTyr: 2.519 ± 0.993
0.0IleXaa: 0.0 ± 0.0
Lys
3.463LysAla: 3.463 ± 1.291
1.889LysCys: 1.889 ± 0.545
2.519LysAsp: 2.519 ± 0.707
3.778LysGlu: 3.778 ± 0.894
2.204LysPhe: 2.204 ± 0.688
3.778LysGly: 3.778 ± 0.634
3.149LysHis: 3.149 ± 1.134
2.519LysIle: 2.519 ± 0.837
4.408LysLys: 4.408 ± 1.745
7.242LysLeu: 7.242 ± 1.612
0.945LysMet: 0.945 ± 0.491
5.038LysAsn: 5.038 ± 2.065
2.519LysPro: 2.519 ± 0.896
1.889LysGln: 1.889 ± 0.545
1.574LysArg: 1.574 ± 0.818
2.834LysSer: 2.834 ± 1.114
3.149LysThr: 3.149 ± 1.281
4.093LysVal: 4.093 ± 0.655
0.63LysTrp: 0.63 ± 0.327
1.259LysTyr: 1.259 ± 0.353
0.0LysXaa: 0.0 ± 0.0
Leu
5.668LeuAla: 5.668 ± 1.621
0.945LeuCys: 0.945 ± 0.491
4.093LeuAsp: 4.093 ± 1.201
3.149LeuGlu: 3.149 ± 0.678
5.038LeuPhe: 5.038 ± 1.395
4.408LeuGly: 4.408 ± 1.349
2.519LeuHis: 2.519 ± 1.136
5.038LeuIle: 5.038 ± 0.681
5.353LeuLys: 5.353 ± 0.886
6.297LeuLeu: 6.297 ± 0.812
1.259LeuMet: 1.259 ± 0.62
3.149LeuAsn: 3.149 ± 0.351
4.723LeuPro: 4.723 ± 1.445
1.889LeuGln: 1.889 ± 0.545
3.778LeuArg: 3.778 ± 1.164
4.093LeuSer: 4.093 ± 1.732
5.038LeuThr: 5.038 ± 3.49
4.093LeuVal: 4.093 ± 1.223
0.63LeuTrp: 0.63 ± 0.327
3.149LeuTyr: 3.149 ± 0.844
0.0LeuXaa: 0.0 ± 0.0
Met
0.945MetAla: 0.945 ± 0.577
0.945MetCys: 0.945 ± 0.491
1.259MetAsp: 1.259 ± 0.701
1.259MetGlu: 1.259 ± 1.278
0.945MetPhe: 0.945 ± 0.345
1.574MetGly: 1.574 ± 0.818
1.259MetHis: 1.259 ± 1.278
1.259MetIle: 1.259 ± 1.029
2.204MetLys: 2.204 ± 0.681
1.889MetLeu: 1.889 ± 0.982
0.0MetMet: 0.0 ± 0.0
0.63MetAsn: 0.63 ± 0.327
1.259MetPro: 1.259 ± 0.816
1.574MetGln: 1.574 ± 0.694
2.204MetArg: 2.204 ± 0.681
0.945MetSer: 0.945 ± 0.491
1.259MetThr: 1.259 ± 0.988
1.259MetVal: 1.259 ± 0.564
0.0MetTrp: 0.0 ± 0.0
0.945MetTyr: 0.945 ± 0.427
0.0MetXaa: 0.0 ± 0.0
Asn
5.038AsnAla: 5.038 ± 0.94
0.315AsnCys: 0.315 ± 0.164
2.834AsnAsp: 2.834 ± 0.97
1.259AsnGlu: 1.259 ± 0.418
0.63AsnPhe: 0.63 ± 0.327
2.834AsnGly: 2.834 ± 1.191
2.519AsnHis: 2.519 ± 0.707
5.038AsnIle: 5.038 ± 1.844
1.259AsnLys: 1.259 ± 0.655
3.149AsnLeu: 3.149 ± 0.487
1.259AsnMet: 1.259 ± 0.773
1.259AsnAsn: 1.259 ± 0.353
1.574AsnPro: 1.574 ± 0.47
2.204AsnGln: 2.204 ± 1.146
2.519AsnArg: 2.519 ± 0.827
3.778AsnSer: 3.778 ± 0.785
1.889AsnThr: 1.889 ± 0.545
3.778AsnVal: 3.778 ± 1.41
0.63AsnTrp: 0.63 ± 0.408
0.945AsnTyr: 0.945 ± 0.427
0.0AsnXaa: 0.0 ± 0.0
Pro
4.408ProAla: 4.408 ± 0.845
1.574ProCys: 1.574 ± 0.527
3.778ProAsp: 3.778 ± 0.833
3.463ProGlu: 3.463 ± 0.713
2.204ProPhe: 2.204 ± 2.24
2.519ProGly: 2.519 ± 2.399
0.945ProHis: 0.945 ± 0.534
2.204ProIle: 2.204 ± 1.141
1.889ProLys: 1.889 ± 0.566
5.353ProLeu: 5.353 ± 1.684
0.63ProMet: 0.63 ± 0.552
3.149ProAsn: 3.149 ± 0.941
3.778ProPro: 3.778 ± 1.477
0.945ProGln: 0.945 ± 0.808
1.889ProArg: 1.889 ± 0.566
2.834ProSer: 2.834 ± 0.979
4.408ProThr: 4.408 ± 0.774
5.668ProVal: 5.668 ± 1.136
0.315ProTrp: 0.315 ± 0.164
1.259ProTyr: 1.259 ± 0.564
0.0ProXaa: 0.0 ± 0.0
Gln
4.408GlnAla: 4.408 ± 1.376
0.0GlnCys: 0.0 ± 0.0
1.889GlnAsp: 1.889 ± 0.545
2.204GlnGlu: 2.204 ± 0.86
1.574GlnPhe: 1.574 ± 1.322
2.519GlnGly: 2.519 ± 1.174
0.945GlnHis: 0.945 ± 0.345
2.519GlnIle: 2.519 ± 0.581
0.945GlnLys: 0.945 ± 0.427
2.204GlnLeu: 2.204 ± 0.681
2.204GlnMet: 2.204 ± 0.862
2.204GlnAsn: 2.204 ± 0.64
3.149GlnPro: 3.149 ± 0.612
1.259GlnGln: 1.259 ± 0.655
1.889GlnArg: 1.889 ± 0.738
1.574GlnSer: 1.574 ± 0.909
0.63GlnThr: 0.63 ± 0.327
2.519GlnVal: 2.519 ± 0.581
0.63GlnTrp: 0.63 ± 0.327
1.574GlnTyr: 1.574 ± 0.527
0.0GlnXaa: 0.0 ± 0.0
Arg
2.519ArgAla: 2.519 ± 1.174
0.315ArgCys: 0.315 ± 0.517
3.149ArgAsp: 3.149 ± 0.94
2.519ArgGlu: 2.519 ± 0.674
3.778ArgPhe: 3.778 ± 1.249
2.834ArgGly: 2.834 ± 1.473
1.574ArgHis: 1.574 ± 0.818
3.778ArgIle: 3.778 ± 0.833
4.408ArgLys: 4.408 ± 1.847
2.834ArgLeu: 2.834 ± 1.51
0.945ArgMet: 0.945 ± 0.534
1.574ArgAsn: 1.574 ± 0.429
1.889ArgPro: 1.889 ± 0.73
2.204ArgGln: 2.204 ± 0.688
2.519ArgArg: 2.519 ± 0.825
4.093ArgSer: 4.093 ± 1.045
1.574ArgThr: 1.574 ± 0.47
5.038ArgVal: 5.038 ± 2.508
0.63ArgTrp: 0.63 ± 0.494
2.204ArgTyr: 2.204 ± 1.263
0.0ArgXaa: 0.0 ± 0.0
Ser
4.093SerAla: 4.093 ± 1.706
0.945SerCys: 0.945 ± 0.848
5.668SerAsp: 5.668 ± 1.259
2.834SerGlu: 2.834 ± 0.659
2.834SerPhe: 2.834 ± 1.175
3.149SerGly: 3.149 ± 1.252
0.945SerHis: 0.945 ± 0.491
3.149SerIle: 3.149 ± 0.351
4.723SerLys: 4.723 ± 1.51
4.093SerLeu: 4.093 ± 2.325
2.204SerMet: 2.204 ± 0.931
1.259SerAsn: 1.259 ± 0.62
3.463SerPro: 3.463 ± 1.088
1.259SerGln: 1.259 ± 0.655
3.149SerArg: 3.149 ± 0.583
5.982SerSer: 5.982 ± 3.803
5.038SerThr: 5.038 ± 2.443
3.778SerVal: 3.778 ± 1.166
0.315SerTrp: 0.315 ± 0.164
1.889SerTyr: 1.889 ± 0.486
0.0SerXaa: 0.0 ± 0.0
Thr
6.612ThrAla: 6.612 ± 1.343
0.945ThrCys: 0.945 ± 0.491
3.149ThrAsp: 3.149 ± 0.859
2.204ThrGlu: 2.204 ± 0.499
2.519ThrPhe: 2.519 ± 2.219
1.259ThrGly: 1.259 ± 0.418
0.945ThrHis: 0.945 ± 0.491
3.778ThrIle: 3.778 ± 0.894
5.038ThrLys: 5.038 ± 0.994
4.723ThrLeu: 4.723 ± 4.048
1.259ThrMet: 1.259 ± 0.655
1.889ThrAsn: 1.889 ± 0.573
3.778ThrPro: 3.778 ± 1.787
2.519ThrGln: 2.519 ± 0.825
2.519ThrArg: 2.519 ± 1.751
3.463ThrSer: 3.463 ± 3.355
3.149ThrThr: 3.149 ± 3.091
3.778ThrVal: 3.778 ± 2.404
1.574ThrTrp: 1.574 ± 0.818
3.149ThrTyr: 3.149 ± 2.381
0.0ThrXaa: 0.0 ± 0.0
Val
8.816ValAla: 8.816 ± 1.032
1.574ValCys: 1.574 ± 0.64
5.668ValAsp: 5.668 ± 1.133
4.723ValGlu: 4.723 ± 1.012
3.149ValPhe: 3.149 ± 0.871
4.408ValGly: 4.408 ± 0.774
0.945ValHis: 0.945 ± 0.491
2.519ValIle: 2.519 ± 0.909
3.463ValLys: 3.463 ± 0.8
4.093ValLeu: 4.093 ± 0.758
1.889ValMet: 1.889 ± 0.69
4.093ValAsn: 4.093 ± 1.239
2.519ValPro: 2.519 ± 0.686
1.889ValGln: 1.889 ± 0.566
3.463ValArg: 3.463 ± 2.918
4.093ValSer: 4.093 ± 1.813
4.723ValThr: 4.723 ± 1.623
5.982ValVal: 5.982 ± 1.393
0.63ValTrp: 0.63 ± 0.552
3.149ValTyr: 3.149 ± 1.241
0.0ValXaa: 0.0 ± 0.0
Trp
0.945TrpAla: 0.945 ± 0.427
0.315TrpCys: 0.315 ± 0.164
0.63TrpAsp: 0.63 ± 0.327
0.315TrpGlu: 0.315 ± 0.616
0.315TrpPhe: 0.315 ± 0.164
0.315TrpGly: 0.315 ± 0.164
0.945TrpHis: 0.945 ± 0.491
0.315TrpIle: 0.315 ± 0.164
1.259TrpLys: 1.259 ± 0.655
0.945TrpLeu: 0.945 ± 0.345
0.315TrpMet: 0.315 ± 0.164
0.315TrpAsn: 0.315 ± 0.164
0.0TrpPro: 0.0 ± 0.0
0.945TrpGln: 0.945 ± 0.491
0.945TrpArg: 0.945 ± 0.491
0.945TrpSer: 0.945 ± 1.086
1.259TrpThr: 1.259 ± 0.564
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.463TyrAla: 3.463 ± 0.913
0.315TyrCys: 0.315 ± 0.164
4.723TyrAsp: 4.723 ± 3.479
3.149TyrGlu: 3.149 ± 0.351
1.259TyrPhe: 1.259 ± 1.131
3.149TyrGly: 3.149 ± 1.241
0.63TyrHis: 0.63 ± 0.327
0.945TyrIle: 0.945 ± 0.722
0.945TyrLys: 0.945 ± 0.491
1.889TyrLeu: 1.889 ± 0.982
1.574TyrMet: 1.574 ± 0.475
2.519TyrAsn: 2.519 ± 0.827
0.63TyrPro: 0.63 ± 0.612
1.259TyrGln: 1.259 ± 0.816
1.574TyrArg: 1.574 ± 1.414
1.889TyrSer: 1.889 ± 1.592
3.778TyrThr: 3.778 ± 1.642
0.0TyrVal: 0.0 ± 0.0
0.63TyrTrp: 0.63 ± 0.327
1.889TyrTyr: 1.889 ± 1.254
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (3177 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski