Amino acid dipepetide frequency for Rhynchobatus djiddensis adomavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.954AlaAla: 7.954 ± 1.348
1.21AlaCys: 1.21 ± 0.404
4.496AlaAsp: 4.496 ± 0.955
3.285AlaGlu: 3.285 ± 0.874
2.075AlaPhe: 2.075 ± 1.18
5.188AlaGly: 5.188 ± 0.938
2.248AlaHis: 2.248 ± 0.554
3.977AlaIle: 3.977 ± 0.704
2.421AlaLys: 2.421 ± 1.011
6.571AlaLeu: 6.571 ± 0.522
1.038AlaMet: 1.038 ± 0.269
4.323AlaAsn: 4.323 ± 1.165
3.458AlaPro: 3.458 ± 0.465
1.556AlaGln: 1.556 ± 0.43
5.706AlaArg: 5.706 ± 1.298
4.842AlaSer: 4.842 ± 1.619
5.361AlaThr: 5.361 ± 1.239
2.94AlaVal: 2.94 ± 1.032
0.519AlaTrp: 0.519 ± 0.208
1.556AlaTyr: 1.556 ± 0.532
0.0AlaXaa: 0.0 ± 0.0
Cys
1.038CysAla: 1.038 ± 0.232
1.038CysCys: 1.038 ± 0.602
0.346CysAsp: 0.346 ± 0.201
0.692CysGlu: 0.692 ± 0.312
1.383CysPhe: 1.383 ± 0.632
1.729CysGly: 1.729 ± 0.365
0.519CysHis: 0.519 ± 0.181
2.075CysIle: 2.075 ± 0.571
0.346CysLys: 0.346 ± 0.201
1.729CysLeu: 1.729 ± 0.393
0.519CysMet: 0.519 ± 0.301
1.038CysAsn: 1.038 ± 0.553
0.865CysPro: 0.865 ± 0.341
0.519CysGln: 0.519 ± 0.301
1.556CysArg: 1.556 ± 0.533
2.767CysSer: 2.767 ± 0.578
1.902CysThr: 1.902 ± 0.374
1.038CysVal: 1.038 ± 0.371
0.0CysTrp: 0.0 ± 0.0
0.865CysTyr: 0.865 ± 0.416
0.0CysXaa: 0.0 ± 0.0
Asp
5.188AspAla: 5.188 ± 0.762
1.383AspCys: 1.383 ± 0.535
3.631AspAsp: 3.631 ± 1.342
2.94AspGlu: 2.94 ± 0.992
0.346AspPhe: 0.346 ± 0.369
3.977AspGly: 3.977 ± 0.981
1.21AspHis: 1.21 ± 0.379
5.879AspIle: 5.879 ± 0.962
1.21AspLys: 1.21 ± 0.473
3.285AspLeu: 3.285 ± 1.047
2.075AspMet: 2.075 ± 0.45
2.767AspAsn: 2.767 ± 0.563
1.383AspPro: 1.383 ± 0.536
2.075AspGln: 2.075 ± 0.345
3.977AspArg: 3.977 ± 0.766
5.533AspSer: 5.533 ± 1.182
4.669AspThr: 4.669 ± 0.413
4.323AspVal: 4.323 ± 1.036
0.173AspTrp: 0.173 ± 0.184
1.383AspTyr: 1.383 ± 0.532
0.0AspXaa: 0.0 ± 0.0
Glu
3.113GluAla: 3.113 ± 0.641
1.556GluCys: 1.556 ± 0.576
2.075GluAsp: 2.075 ± 0.49
8.646GluGlu: 8.646 ± 1.902
1.038GluPhe: 1.038 ± 0.545
5.533GluGly: 5.533 ± 1.928
1.902GluHis: 1.902 ± 0.456
3.804GluIle: 3.804 ± 1.2
3.285GluLys: 3.285 ± 0.616
3.631GluLeu: 3.631 ± 0.894
2.248GluMet: 2.248 ± 0.578
1.556GluAsn: 1.556 ± 0.361
1.729GluPro: 1.729 ± 0.903
3.977GluGln: 3.977 ± 0.771
4.842GluArg: 4.842 ± 0.99
3.458GluSer: 3.458 ± 0.814
2.767GluThr: 2.767 ± 0.286
1.383GluVal: 1.383 ± 0.621
0.346GluTrp: 0.346 ± 0.153
1.21GluTyr: 1.21 ± 0.615
0.0GluXaa: 0.0 ± 0.0
Phe
1.556PheAla: 1.556 ± 1.038
0.692PheCys: 0.692 ± 0.25
1.729PheAsp: 1.729 ± 1.023
1.21PheGlu: 1.21 ± 0.652
0.519PhePhe: 0.519 ± 0.385
1.729PheGly: 1.729 ± 0.507
0.519PheHis: 0.519 ± 0.324
2.248PheIle: 2.248 ± 1.16
1.729PheLys: 1.729 ± 0.486
1.902PheLeu: 1.902 ± 0.83
1.383PheMet: 1.383 ± 0.782
1.729PheAsn: 1.729 ± 0.298
2.767PhePro: 2.767 ± 0.616
1.729PheGln: 1.729 ± 0.669
1.383PheArg: 1.383 ± 0.697
1.902PheSer: 1.902 ± 0.576
2.594PheThr: 2.594 ± 0.761
1.383PheVal: 1.383 ± 0.329
0.519PheTrp: 0.519 ± 0.28
0.865PheTyr: 0.865 ± 0.243
0.0PheXaa: 0.0 ± 0.0
Gly
4.496GlyAla: 4.496 ± 1.384
1.383GlyCys: 1.383 ± 0.505
3.977GlyAsp: 3.977 ± 1.316
4.669GlyGlu: 4.669 ± 1.533
1.21GlyPhe: 1.21 ± 0.369
10.548GlyGly: 10.548 ± 3.742
2.767GlyHis: 2.767 ± 0.848
3.631GlyIle: 3.631 ± 0.614
2.767GlyLys: 2.767 ± 0.618
4.496GlyLeu: 4.496 ± 1.372
1.383GlyMet: 1.383 ± 0.38
3.113GlyAsn: 3.113 ± 0.506
3.458GlyPro: 3.458 ± 0.71
2.594GlyGln: 2.594 ± 0.879
4.669GlyArg: 4.669 ± 1.183
7.436GlySer: 7.436 ± 2.319
5.879GlyThr: 5.879 ± 1.239
3.113GlyVal: 3.113 ± 0.946
0.865GlyTrp: 0.865 ± 0.595
1.902GlyTyr: 1.902 ± 0.566
0.0GlyXaa: 0.0 ± 0.0
His
1.038HisAla: 1.038 ± 0.301
0.865HisCys: 0.865 ± 0.239
1.21HisAsp: 1.21 ± 0.507
0.692HisGlu: 0.692 ± 0.282
1.383HisPhe: 1.383 ± 0.669
2.421HisGly: 2.421 ± 0.536
0.346HisHis: 0.346 ± 0.153
1.038HisIle: 1.038 ± 0.645
0.346HisLys: 0.346 ± 0.153
1.729HisLeu: 1.729 ± 0.866
0.519HisMet: 0.519 ± 0.209
1.21HisAsn: 1.21 ± 0.33
1.729HisPro: 1.729 ± 0.639
1.729HisGln: 1.729 ± 0.8
2.421HisArg: 2.421 ± 0.932
3.458HisSer: 3.458 ± 0.776
1.556HisThr: 1.556 ± 0.642
1.729HisVal: 1.729 ± 0.752
0.173HisTrp: 0.173 ± 0.219
1.038HisTyr: 1.038 ± 0.553
0.0HisXaa: 0.0 ± 0.0
Ile
4.496IleAla: 4.496 ± 0.45
0.865IleCys: 0.865 ± 0.378
4.323IleAsp: 4.323 ± 0.655
2.94IleGlu: 2.94 ± 0.567
2.94IlePhe: 2.94 ± 0.945
3.458IleGly: 3.458 ± 0.721
1.729IleHis: 1.729 ± 0.421
1.902IleIle: 1.902 ± 0.588
1.729IleLys: 1.729 ± 0.828
4.496IleLeu: 4.496 ± 1.228
1.21IleMet: 1.21 ± 0.69
4.842IleAsn: 4.842 ± 1.136
3.977IlePro: 3.977 ± 1.749
1.556IleGln: 1.556 ± 0.712
1.902IleArg: 1.902 ± 0.4
4.323IleSer: 4.323 ± 0.484
5.361IleThr: 5.361 ± 0.961
2.248IleVal: 2.248 ± 0.766
0.0IleTrp: 0.0 ± 0.0
1.038IleTyr: 1.038 ± 0.461
0.0IleXaa: 0.0 ± 0.0
Lys
2.767LysAla: 2.767 ± 0.49
0.865LysCys: 0.865 ± 0.296
1.902LysAsp: 1.902 ± 0.805
2.594LysGlu: 2.594 ± 0.636
0.346LysPhe: 0.346 ± 0.2
3.631LysGly: 3.631 ± 0.608
1.038LysHis: 1.038 ± 0.302
1.21LysIle: 1.21 ± 0.501
2.248LysLys: 2.248 ± 1.074
3.285LysLeu: 3.285 ± 0.97
1.038LysMet: 1.038 ± 0.716
1.556LysAsn: 1.556 ± 0.471
1.038LysPro: 1.038 ± 0.73
1.556LysGln: 1.556 ± 0.744
4.669LysArg: 4.669 ± 0.71
2.421LysSer: 2.421 ± 1.204
2.594LysThr: 2.594 ± 0.511
2.767LysVal: 2.767 ± 1.006
0.0LysTrp: 0.0 ± 0.0
1.729LysTyr: 1.729 ± 0.747
0.0LysXaa: 0.0 ± 0.0
Leu
6.225LeuAla: 6.225 ± 1.176
1.383LeuCys: 1.383 ± 0.33
3.285LeuAsp: 3.285 ± 1.072
3.631LeuGlu: 3.631 ± 0.781
2.248LeuPhe: 2.248 ± 0.791
4.496LeuGly: 4.496 ± 0.925
2.594LeuHis: 2.594 ± 0.722
2.421LeuIle: 2.421 ± 0.671
2.94LeuLys: 2.94 ± 1.294
6.225LeuLeu: 6.225 ± 0.869
1.556LeuMet: 1.556 ± 0.612
2.767LeuAsn: 2.767 ± 0.885
6.398LeuPro: 6.398 ± 1.357
5.188LeuGln: 5.188 ± 0.596
4.15LeuArg: 4.15 ± 0.993
7.609LeuSer: 7.609 ± 1.565
6.225LeuThr: 6.225 ± 1.308
3.458LeuVal: 3.458 ± 0.467
0.346LeuTrp: 0.346 ± 0.249
2.248LeuTyr: 2.248 ± 0.507
0.0LeuXaa: 0.0 ± 0.0
Met
1.038MetAla: 1.038 ± 0.324
0.865MetCys: 0.865 ± 0.357
1.729MetAsp: 1.729 ± 0.262
1.729MetGlu: 1.729 ± 0.614
0.519MetPhe: 0.519 ± 0.397
1.556MetGly: 1.556 ± 0.348
0.173MetHis: 0.173 ± 0.1
0.865MetIle: 0.865 ± 0.357
0.865MetLys: 0.865 ± 0.562
1.729MetLeu: 1.729 ± 1.104
0.346MetMet: 0.346 ± 0.166
0.173MetAsn: 0.173 ± 0.1
1.383MetPro: 1.383 ± 0.484
1.556MetGln: 1.556 ± 0.492
3.285MetArg: 3.285 ± 0.778
2.421MetSer: 2.421 ± 0.826
2.248MetThr: 2.248 ± 0.996
0.519MetVal: 0.519 ± 0.324
0.173MetTrp: 0.173 ± 0.238
0.346MetTyr: 0.346 ± 0.372
0.0MetXaa: 0.0 ± 0.0
Asn
2.421AsnAla: 2.421 ± 0.335
0.692AsnCys: 0.692 ± 0.224
1.902AsnAsp: 1.902 ± 0.507
3.113AsnGlu: 3.113 ± 0.795
0.865AsnPhe: 0.865 ± 0.254
5.361AsnGly: 5.361 ± 0.732
0.865AsnHis: 0.865 ± 0.344
3.804AsnIle: 3.804 ± 0.788
1.556AsnLys: 1.556 ± 0.71
2.594AsnLeu: 2.594 ± 0.983
1.038AsnMet: 1.038 ± 0.197
2.94AsnAsn: 2.94 ± 1.162
2.594AsnPro: 2.594 ± 0.478
1.038AsnGln: 1.038 ± 0.389
2.421AsnArg: 2.421 ± 0.756
3.113AsnSer: 3.113 ± 0.612
3.113AsnThr: 3.113 ± 0.998
4.15AsnVal: 4.15 ± 1.027
0.346AsnTrp: 0.346 ± 0.276
1.383AsnTyr: 1.383 ± 0.427
0.0AsnXaa: 0.0 ± 0.0
Pro
4.842ProAla: 4.842 ± 1.012
0.865ProCys: 0.865 ± 0.502
2.421ProAsp: 2.421 ± 0.23
2.075ProGlu: 2.075 ± 0.488
3.113ProPhe: 3.113 ± 0.633
2.421ProGly: 2.421 ± 0.569
1.383ProHis: 1.383 ± 0.328
5.015ProIle: 5.015 ± 1.215
2.075ProLys: 2.075 ± 0.588
6.225ProLeu: 6.225 ± 1.054
1.383ProMet: 1.383 ± 1.099
2.248ProAsn: 2.248 ± 0.714
4.15ProPro: 4.15 ± 1.863
2.421ProGln: 2.421 ± 0.363
1.902ProArg: 1.902 ± 0.617
6.571ProSer: 6.571 ± 1.489
3.285ProThr: 3.285 ± 0.411
4.15ProVal: 4.15 ± 0.716
0.346ProTrp: 0.346 ± 0.153
0.865ProTyr: 0.865 ± 0.322
0.0ProXaa: 0.0 ± 0.0
Gln
3.285GlnAla: 3.285 ± 0.581
0.865GlnCys: 0.865 ± 0.347
1.383GlnAsp: 1.383 ± 0.338
1.902GlnGlu: 1.902 ± 0.549
1.038GlnPhe: 1.038 ± 0.552
2.248GlnGly: 2.248 ± 0.423
1.556GlnHis: 1.556 ± 0.59
2.248GlnIle: 2.248 ± 0.516
1.556GlnLys: 1.556 ± 0.876
2.767GlnLeu: 2.767 ± 0.997
1.21GlnMet: 1.21 ± 0.313
1.038GlnAsn: 1.038 ± 0.449
2.421GlnPro: 2.421 ± 0.349
2.075GlnGln: 2.075 ± 0.497
3.977GlnArg: 3.977 ± 1.558
5.015GlnSer: 5.015 ± 0.683
2.594GlnThr: 2.594 ± 0.368
2.767GlnVal: 2.767 ± 0.622
0.346GlnTrp: 0.346 ± 0.201
1.729GlnTyr: 1.729 ± 0.609
0.0GlnXaa: 0.0 ± 0.0
Arg
3.113ArgAla: 3.113 ± 0.725
1.383ArgCys: 1.383 ± 0.328
3.631ArgAsp: 3.631 ± 0.676
4.669ArgGlu: 4.669 ± 0.53
2.421ArgPhe: 2.421 ± 0.704
5.015ArgGly: 5.015 ± 1.809
1.556ArgHis: 1.556 ± 0.403
1.902ArgIle: 1.902 ± 0.674
4.323ArgLys: 4.323 ± 1.263
6.744ArgLeu: 6.744 ± 1.286
1.038ArgMet: 1.038 ± 0.308
2.94ArgAsn: 2.94 ± 1.014
4.669ArgPro: 4.669 ± 0.674
3.458ArgGln: 3.458 ± 1.814
6.571ArgArg: 6.571 ± 0.734
6.398ArgSer: 6.398 ± 1.212
2.594ArgThr: 2.594 ± 0.83
2.94ArgVal: 2.94 ± 0.757
0.173ArgTrp: 0.173 ± 0.218
2.248ArgTyr: 2.248 ± 0.493
0.0ArgXaa: 0.0 ± 0.0
Ser
7.09SerAla: 7.09 ± 1.438
1.556SerCys: 1.556 ± 0.438
6.744SerAsp: 6.744 ± 1.662
5.533SerGlu: 5.533 ± 0.96
3.285SerPhe: 3.285 ± 0.746
5.706SerGly: 5.706 ± 1.385
1.383SerHis: 1.383 ± 0.446
5.533SerIle: 5.533 ± 1.199
3.113SerLys: 3.113 ± 0.641
6.398SerLeu: 6.398 ± 1.163
0.692SerMet: 0.692 ± 0.401
5.015SerAsn: 5.015 ± 1.488
5.879SerPro: 5.879 ± 1.201
2.94SerGln: 2.94 ± 0.847
4.323SerArg: 4.323 ± 1.045
10.721SerSer: 10.721 ± 3.127
9.338SerThr: 9.338 ± 1.882
4.15SerVal: 4.15 ± 0.847
1.21SerTrp: 1.21 ± 0.442
2.075SerTyr: 2.075 ± 0.471
0.0SerXaa: 0.0 ± 0.0
Thr
5.015ThrAla: 5.015 ± 1.059
1.729ThrCys: 1.729 ± 0.543
6.917ThrAsp: 6.917 ± 0.8
5.015ThrGlu: 5.015 ± 1.011
3.285ThrPhe: 3.285 ± 0.891
4.15ThrGly: 4.15 ± 0.808
1.383ThrHis: 1.383 ± 0.434
3.804ThrIle: 3.804 ± 0.497
1.902ThrLys: 1.902 ± 0.469
6.398ThrLeu: 6.398 ± 1.061
1.729ThrMet: 1.729 ± 0.505
2.767ThrAsn: 2.767 ± 0.661
4.323ThrPro: 4.323 ± 1.324
2.767ThrGln: 2.767 ± 0.538
3.804ThrArg: 3.804 ± 0.432
6.398ThrSer: 6.398 ± 1.576
7.609ThrThr: 7.609 ± 0.753
5.015ThrVal: 5.015 ± 0.649
0.173ThrTrp: 0.173 ± 0.219
1.902ThrTyr: 1.902 ± 0.465
0.0ThrXaa: 0.0 ± 0.0
Val
3.977ValAla: 3.977 ± 0.542
1.556ValCys: 1.556 ± 0.529
3.458ValAsp: 3.458 ± 0.879
1.729ValGlu: 1.729 ± 0.5
0.865ValPhe: 0.865 ± 0.415
2.421ValGly: 2.421 ± 0.78
2.075ValHis: 2.075 ± 0.808
2.421ValIle: 2.421 ± 0.662
2.94ValLys: 2.94 ± 0.717
2.94ValLeu: 2.94 ± 0.64
1.21ValMet: 1.21 ± 0.281
2.421ValAsn: 2.421 ± 0.678
4.15ValPro: 4.15 ± 0.521
1.902ValGln: 1.902 ± 0.538
4.323ValArg: 4.323 ± 1.133
5.015ValSer: 5.015 ± 1.123
4.323ValThr: 4.323 ± 0.709
2.767ValVal: 2.767 ± 1.192
0.346ValTrp: 0.346 ± 0.222
1.729ValTyr: 1.729 ± 0.487
0.0ValXaa: 0.0 ± 0.0
Trp
0.519TrpAla: 0.519 ± 0.388
0.173TrpCys: 0.173 ± 0.219
0.346TrpAsp: 0.346 ± 0.153
0.173TrpGlu: 0.173 ± 0.278
0.346TrpPhe: 0.346 ± 0.153
0.692TrpGly: 0.692 ± 0.359
0.0TrpHis: 0.0 ± 0.0
0.173TrpIle: 0.173 ± 0.1
0.346TrpLys: 0.346 ± 0.374
0.346TrpLeu: 0.346 ± 0.327
0.173TrpMet: 0.173 ± 0.184
0.346TrpAsn: 0.346 ± 0.2
0.173TrpPro: 0.173 ± 0.218
0.692TrpGln: 0.692 ± 0.399
0.346TrpArg: 0.346 ± 0.249
0.173TrpSer: 0.173 ± 0.1
0.692TrpThr: 0.692 ± 0.49
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.519TrpTyr: 0.519 ± 0.324
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.556TyrAla: 1.556 ± 1.206
1.038TyrCys: 1.038 ± 0.691
1.902TyrAsp: 1.902 ± 0.768
0.865TyrGlu: 0.865 ± 0.576
0.865TyrPhe: 0.865 ± 0.578
2.075TyrGly: 2.075 ± 0.858
1.383TyrHis: 1.383 ± 0.592
1.556TyrIle: 1.556 ± 0.829
1.556TyrLys: 1.556 ± 0.687
1.902TyrLeu: 1.902 ± 0.465
1.556TyrMet: 1.556 ± 0.571
0.519TyrAsn: 0.519 ± 0.229
1.21TyrPro: 1.21 ± 0.527
0.692TyrGln: 0.692 ± 0.328
1.556TyrArg: 1.556 ± 0.379
3.113TyrSer: 3.113 ± 0.71
1.383TyrThr: 1.383 ± 0.664
1.729TyrVal: 1.729 ± 0.315
0.173TyrTrp: 0.173 ± 0.278
0.173TyrTyr: 0.173 ± 0.272
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (5784 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski