Loxodonta africana (African elephant)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;

Average proteome isoelectric point is 6.78

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 25615 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|G3TQE1|G3TQE1_LOXAF Growth differentiation factor 7 OS=Loxodonta africana OX=9785 GN=GDF7 PE=3 SV=1
MM1 pKa = 7.97DD2 pKa = 3.9VLFVAILAVPLILGQEE18 pKa = 4.27YY19 pKa = 10.34EE20 pKa = 4.07NEE22 pKa = 4.26EE23 pKa = 3.97ILEE26 pKa = 4.27EE27 pKa = 4.49DD28 pKa = 4.56DD29 pKa = 4.35YY30 pKa = 11.83YY31 pKa = 11.4QVIYY35 pKa = 10.5YY36 pKa = 7.43YY37 pKa = 10.35TVTPNYY43 pKa = 10.24DD44 pKa = 3.35DD45 pKa = 5.21LGANFTVDD53 pKa = 3.14YY54 pKa = 11.04SVFEE58 pKa = 4.27SEE60 pKa = 5.49DD61 pKa = 3.21RR62 pKa = 11.84LNRR65 pKa = 11.84LDD67 pKa = 4.01KK68 pKa = 11.08DD69 pKa = 3.49VTEE72 pKa = 4.33AVEE75 pKa = 4.25TNINLEE81 pKa = 4.25TEE83 pKa = 4.39RR84 pKa = 11.84QDD86 pKa = 3.15HH87 pKa = 6.58LKK89 pKa = 10.26PVTRR93 pKa = 11.84KK94 pKa = 8.95PVTMEE99 pKa = 4.05PPSVLSQSLNTTLQSPDD116 pKa = 3.61LNDD119 pKa = 3.7AVSSLQSPVPLILSWALIQGGIYY142 pKa = 8.11FTT144 pKa = 4.52

Molecular weight: 16.38 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|G3TT54|G3TT54_LOXAF MAGE domain-containing protein OS=Loxodonta africana OX=9785 PE=4 SV=1
MM1 pKa = 7.57SSHH4 pKa = 5.15KK5 pKa = 8.91TFRR8 pKa = 11.84IKK10 pKa = 10.64RR11 pKa = 11.84FLAKK15 pKa = 9.71KK16 pKa = 9.58QKK18 pKa = 8.69QNRR21 pKa = 11.84PIPQWIRR28 pKa = 11.84MKK30 pKa = 9.89TGNKK34 pKa = 8.61IRR36 pKa = 11.84YY37 pKa = 7.09NSKK40 pKa = 8.3RR41 pKa = 11.84RR42 pKa = 11.84HH43 pKa = 3.95WRR45 pKa = 11.84RR46 pKa = 11.84TKK48 pKa = 10.83LGLL51 pKa = 3.67

Molecular weight: 6.41 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

20017

5598

25615

13857996

19

28447

541.0

60.37

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.816 ± 0.014

2.236 ± 0.013

4.759 ± 0.01

6.889 ± 0.018

3.851 ± 0.013

6.367 ± 0.021

2.56 ± 0.008

4.592 ± 0.014

5.712 ± 0.02

10.182 ± 0.02

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.195 ± 0.006

3.657 ± 0.011

6.11 ± 0.023

4.693 ± 0.013

5.498 ± 0.012

8.341 ± 0.021

5.371 ± 0.01

6.18 ± 0.014

1.194 ± 0.006

2.783 ± 0.009
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski