Amino acid dipepetide frequency for Lignipirellula cremea

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.313AlaAla: 15.313 ± 0.127	1.355AlaCys: 1.355 ± 0.023	6.747AlaAsp: 6.747 ± 0.066	7.426AlaGlu: 7.426 ± 0.059	3.608AlaPhe: 3.608 ± 0.035	9.006AlaGly: 9.006 ± 0.09	1.764AlaHis: 1.764 ± 0.028	5.103AlaIle: 5.103 ± 0.054	3.658AlaLys: 3.658 ± 0.049	9.809AlaLeu: 9.809 ± 0.07	2.526AlaMet: 2.526 ± 0.031	2.796AlaAsn: 2.796 ± 0.037	5.781AlaPro: 5.781 ± 0.076	4.05AlaGln: 4.05 ± 0.048	6.376AlaArg: 6.376 ± 0.065	6.441AlaSer: 6.441 ± 0.06	5.343AlaThr: 5.343 ± 0.056	7.692AlaVal: 7.692 ± 0.063	1.791AlaTrp: 1.791 ± 0.031	2.35AlaTyr: 2.35 ± 0.035	0.0AlaXaa: 0.0 ± 0.0
Cys	0.897CysAla: 0.897 ± 0.021	0.278CysCys: 0.278 ± 0.013	0.691CysAsp: 0.691 ± 0.02	0.68CysGlu: 0.68 ± 0.018	0.456CysPhe: 0.456 ± 0.011	1.11CysGly: 1.11 ± 0.033	0.461CysHis: 0.461 ± 0.016	0.417CysIle: 0.417 ± 0.014	0.252CysLys: 0.252 ± 0.01	1.285CysLeu: 1.285 ± 0.026	0.214CysMet: 0.214 ± 0.009	0.297CysAsn: 0.297 ± 0.014	0.588CysPro: 0.588 ± 0.017	0.481CysGln: 0.481 ± 0.014	0.887CysArg: 0.887 ± 0.019	0.689CysSer: 0.689 ± 0.019	0.489CysThr: 0.489 ± 0.015	0.766CysVal: 0.766 ± 0.021	0.24CysTrp: 0.24 ± 0.01	0.34CysTyr: 0.34 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	6.099AspAla: 6.099 ± 0.064	0.636AspCys: 0.636 ± 0.016	3.729AspAsp: 3.729 ± 0.054	3.749AspGlu: 3.749 ± 0.043	2.381AspPhe: 2.381 ± 0.035	4.914AspGly: 4.914 ± 0.064	1.383AspHis: 1.383 ± 0.023	2.091AspIle: 2.091 ± 0.034	1.972AspLys: 1.972 ± 0.032	6.23AspLeu: 6.23 ± 0.049	1.029AspMet: 1.029 ± 0.02	1.547AspAsn: 1.547 ± 0.027	3.953AspPro: 3.953 ± 0.043	2.669AspGln: 2.669 ± 0.031	4.314AspArg: 4.314 ± 0.045	3.151AspSer: 3.151 ± 0.045	2.387AspThr: 2.387 ± 0.034	3.371AspVal: 3.371 ± 0.038	1.114AspTrp: 1.114 ± 0.019	1.735AspTyr: 1.735 ± 0.028	0.0AspXaa: 0.0 ± 0.0
Glu	6.282GluAla: 6.282 ± 0.071	0.498GluCys: 0.498 ± 0.016	2.667GluAsp: 2.667 ± 0.039	4.233GluGlu: 4.233 ± 0.054	2.281GluPhe: 2.281 ± 0.028	3.846GluGly: 3.846 ± 0.04	1.421GluHis: 1.421 ± 0.025	3.255GluIle: 3.255 ± 0.041	2.936GluLys: 2.936 ± 0.038	6.695GluLeu: 6.695 ± 0.054	1.546GluMet: 1.546 ± 0.022	2.046GluAsn: 2.046 ± 0.029	3.501GluPro: 3.501 ± 0.047	3.576GluGln: 3.576 ± 0.044	4.452GluArg: 4.452 ± 0.05	3.537GluSer: 3.537 ± 0.038	3.787GluThr: 3.787 ± 0.039	4.092GluVal: 4.092 ± 0.041	0.797GluTrp: 0.797 ± 0.02	1.466GluTyr: 1.466 ± 0.027	0.0GluXaa: 0.0 ± 0.0
Phe	3.874PheAla: 3.874 ± 0.047	0.517PheCys: 0.517 ± 0.014	2.72PheAsp: 2.72 ± 0.029	2.18PheGlu: 2.18 ± 0.03	1.467PhePhe: 1.467 ± 0.026	3.069PheGly: 3.069 ± 0.037	0.887PheHis: 0.887 ± 0.02	1.221PheIle: 1.221 ± 0.022	0.883PheLys: 0.883 ± 0.02	3.808PheLeu: 3.808 ± 0.039	0.613PheMet: 0.613 ± 0.017	1.101PheAsn: 1.101 ± 0.023	1.856PhePro: 1.856 ± 0.026	1.534PheGln: 1.534 ± 0.024	2.511PheArg: 2.511 ± 0.034	2.248PheSer: 2.248 ± 0.028	1.953PheThr: 1.953 ± 0.029	2.558PheVal: 2.558 ± 0.03	0.553PheTrp: 0.553 ± 0.015	0.994PheTyr: 0.994 ± 0.018	0.0PheXaa: 0.0 ± 0.0
Gly	7.064GlyAla: 7.064 ± 0.086	1.061GlyCys: 1.061 ± 0.032	4.875GlyAsp: 4.875 ± 0.078	5.168GlyGlu: 5.168 ± 0.044	2.99GlyPhe: 2.99 ± 0.036	6.82GlyGly: 6.82 ± 0.101	1.59GlyHis: 1.59 ± 0.029	2.958GlyIle: 2.958 ± 0.036	3.686GlyLys: 3.686 ± 0.047	7.403GlyLeu: 7.403 ± 0.064	1.887GlyMet: 1.887 ± 0.03	2.298GlyAsn: 2.298 ± 0.036	3.754GlyPro: 3.754 ± 0.039	3.375GlyGln: 3.375 ± 0.036	5.332GlyArg: 5.332 ± 0.046	4.695GlySer: 4.695 ± 0.054	2.899GlyThr: 2.899 ± 0.038	6.114GlyVal: 6.114 ± 0.061	1.332GlyTrp: 1.332 ± 0.027	2.18GlyTyr: 2.18 ± 0.026	0.0GlyXaa: 0.0 ± 0.0
His	2.18HisAla: 2.18 ± 0.032	0.35HisCys: 0.35 ± 0.014	1.282HisAsp: 1.282 ± 0.026	1.194HisGlu: 1.194 ± 0.023	0.945HisPhe: 0.945 ± 0.018	1.927HisGly: 1.927 ± 0.027	0.69HisHis: 0.69 ± 0.018	0.72HisIle: 0.72 ± 0.018	0.548HisLys: 0.548 ± 0.014	2.332HisLeu: 2.332 ± 0.034	0.358HisMet: 0.358 ± 0.012	0.606HisAsn: 0.606 ± 0.015	1.587HisPro: 1.587 ± 0.028	0.981HisGln: 0.981 ± 0.016	1.68HisArg: 1.68 ± 0.024	1.156HisSer: 1.156 ± 0.019	1.039HisThr: 1.039 ± 0.02	1.337HisVal: 1.337 ± 0.023	0.477HisTrp: 0.477 ± 0.015	0.692HisTyr: 0.692 ± 0.018	0.0HisXaa: 0.0 ± 0.0
Ile	5.185IleAla: 5.185 ± 0.049	0.544IleCys: 0.544 ± 0.013	3.414IleAsp: 3.414 ± 0.039	3.245IleGlu: 3.245 ± 0.039	1.293IlePhe: 1.293 ± 0.022	3.603IleGly: 3.603 ± 0.044	0.916IleHis: 0.916 ± 0.022	1.384IleIle: 1.384 ± 0.025	1.143IleLys: 1.143 ± 0.023	3.691IleLeu: 3.691 ± 0.043	0.601IleMet: 0.601 ± 0.015	1.286IleAsn: 1.286 ± 0.025	2.161IlePro: 2.161 ± 0.026	1.497IleGln: 1.497 ± 0.024	3.058IleArg: 3.058 ± 0.036	2.429IleSer: 2.429 ± 0.033	2.242IleThr: 2.242 ± 0.042	3.307IleVal: 3.307 ± 0.04	0.574IleTrp: 0.574 ± 0.015	1.114IleTyr: 1.114 ± 0.022	0.0IleXaa: 0.0 ± 0.0
Lys	3.476LysAla: 3.476 ± 0.047	0.29LysCys: 0.29 ± 0.01	1.499LysAsp: 1.499 ± 0.026	2.114LysGlu: 2.114 ± 0.029	1.155LysPhe: 1.155 ± 0.022	1.997LysGly: 1.997 ± 0.032	0.747LysHis: 0.747 ± 0.018	1.784LysIle: 1.784 ± 0.027	1.846LysLys: 1.846 ± 0.033	3.607LysLeu: 3.607 ± 0.043	0.863LysMet: 0.863 ± 0.021	1.124LysAsn: 1.124 ± 0.023	2.311LysPro: 2.311 ± 0.039	1.563LysGln: 1.563 ± 0.028	2.255LysArg: 2.255 ± 0.03	1.965LysSer: 1.965 ± 0.028	2.165LysThr: 2.165 ± 0.03	2.259LysVal: 2.259 ± 0.034	0.464LysTrp: 0.464 ± 0.012	0.855LysTyr: 0.855 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	13.286LeuAla: 13.286 ± 0.103	1.128LeuCys: 1.128 ± 0.021	5.856LeuAsp: 5.856 ± 0.055	6.374LeuGlu: 6.374 ± 0.063	3.578LeuPhe: 3.578 ± 0.042	7.526LeuGly: 7.526 ± 0.062	2.328LeuHis: 2.328 ± 0.034	4.058LeuIle: 4.058 ± 0.041	3.524LeuLys: 3.524 ± 0.033	12.178LeuLeu: 12.178 ± 0.098	1.857LeuMet: 1.857 ± 0.027	2.624LeuAsn: 2.624 ± 0.03	6.216LeuPro: 6.216 ± 0.056	4.564LeuGln: 4.564 ± 0.046	7.001LeuArg: 7.001 ± 0.061	6.29LeuSer: 6.29 ± 0.056	5.855LeuThr: 5.855 ± 0.058	6.843LeuVal: 6.843 ± 0.056	1.362LeuTrp: 1.362 ± 0.028	2.271LeuTyr: 2.271 ± 0.035	0.0LeuXaa: 0.0 ± 0.0
Met	2.218MetAla: 2.218 ± 0.031	0.181MetCys: 0.181 ± 0.008	0.794MetAsp: 0.794 ± 0.019	1.057MetGlu: 1.057 ± 0.022	0.724MetPhe: 0.724 ± 0.017	1.334MetGly: 1.334 ± 0.024	0.489MetHis: 0.489 ± 0.015	1.026MetIle: 1.026 ± 0.019	0.845MetLys: 0.845 ± 0.018	2.473MetLeu: 2.473 ± 0.038	0.504MetMet: 0.504 ± 0.013	0.781MetAsn: 0.781 ± 0.017	1.274MetPro: 1.274 ± 0.021	1.037MetGln: 1.037 ± 0.02	1.405MetArg: 1.405 ± 0.024	1.323MetSer: 1.323 ± 0.022	1.319MetThr: 1.319 ± 0.023	1.297MetVal: 1.297 ± 0.022	0.218MetTrp: 0.218 ± 0.009	0.428MetTyr: 0.428 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	2.744AsnAla: 2.744 ± 0.036	0.327AsnCys: 0.327 ± 0.013	1.74AsnAsp: 1.74 ± 0.031	1.55AsnGlu: 1.55 ± 0.027	1.115AsnPhe: 1.115 ± 0.024	2.511AsnGly: 2.511 ± 0.037	0.684AsnHis: 0.684 ± 0.017	1.102AsnIle: 1.102 ± 0.024	0.799AsnLys: 0.799 ± 0.018	2.921AsnLeu: 2.921 ± 0.035	0.533AsnMet: 0.533 ± 0.014	0.914AsnAsn: 0.914 ± 0.024	1.991AsnPro: 1.991 ± 0.031	1.215AsnGln: 1.215 ± 0.026	2.103AsnArg: 2.103 ± 0.03	1.588AsnSer: 1.588 ± 0.026	1.362AsnThr: 1.362 ± 0.024	1.9AsnVal: 1.9 ± 0.032	0.539AsnTrp: 0.539 ± 0.015	0.817AsnTyr: 0.817 ± 0.021	0.0AsnXaa: 0.0 ± 0.0
Pro	7.425ProAla: 7.425 ± 0.086	0.449ProCys: 0.449 ± 0.012	3.657ProAsp: 3.657 ± 0.041	4.099ProGlu: 4.099 ± 0.047	1.968ProPhe: 1.968 ± 0.028	4.779ProGly: 4.779 ± 0.055	1.337ProHis: 1.337 ± 0.025	2.249ProIle: 2.249 ± 0.029	1.651ProLys: 1.651 ± 0.033	5.625ProLeu: 5.625 ± 0.055	1.062ProMet: 1.062 ± 0.021	1.51ProAsn: 1.51 ± 0.029	4.135ProPro: 4.135 ± 0.058	2.766ProGln: 2.766 ± 0.04	3.2ProArg: 3.2 ± 0.039	3.388ProSer: 3.388 ± 0.04	3.189ProThr: 3.189 ± 0.042	4.074ProVal: 4.074 ± 0.053	0.815ProTrp: 0.815 ± 0.016	1.278ProTyr: 1.278 ± 0.021	0.0ProXaa: 0.0 ± 0.0
Gln	5.28GlnAla: 5.28 ± 0.059	0.389GlnCys: 0.389 ± 0.014	1.712GlnAsp: 1.712 ± 0.029	2.526GlnGlu: 2.526 ± 0.033	1.561GlnPhe: 1.561 ± 0.024	3.346GlnGly: 3.346 ± 0.037	1.018GlnHis: 1.018 ± 0.022	2.206GlnIle: 2.206 ± 0.027	1.544GlnLys: 1.544 ± 0.028	4.769GlnLeu: 4.769 ± 0.049	1.003GlnMet: 1.003 ± 0.019	1.212GlnAsn: 1.212 ± 0.022	2.771GlnPro: 2.771 ± 0.033	2.741GlnGln: 2.741 ± 0.056	3.228GlnArg: 3.228 ± 0.043	2.382GlnSer: 2.382 ± 0.028	2.447GlnThr: 2.447 ± 0.036	2.993GlnVal: 2.993 ± 0.04	0.67GlnTrp: 0.67 ± 0.014	0.98GlnTyr: 0.98 ± 0.02	0.0GlnXaa: 0.0 ± 0.0
Arg	5.264ArgAla: 5.264 ± 0.042	0.823ArgCys: 0.823 ± 0.018	3.711ArgAsp: 3.711 ± 0.041	4.385ArgGlu: 4.385 ± 0.053	2.963ArgPhe: 2.963 ± 0.035	4.269ArgGly: 4.269 ± 0.043	1.51ArgHis: 1.51 ± 0.027	3.396ArgIle: 3.396 ± 0.037	2.363ArgLys: 2.363 ± 0.031	8.164ArgLeu: 8.164 ± 0.07	1.749ArgMet: 1.749 ± 0.026	2.058ArgAsn: 2.058 ± 0.026	3.768ArgPro: 3.768 ± 0.044	3.617ArgGln: 3.617 ± 0.043	5.899ArgArg: 5.899 ± 0.068	4.076ArgSer: 4.076 ± 0.039	3.51ArgThr: 3.51 ± 0.041	4.296ArgVal: 4.296 ± 0.042	1.215ArgTrp: 1.215 ± 0.027	1.966ArgTyr: 1.966 ± 0.03	0.0ArgXaa: 0.0 ± 0.0
Ser	5.44SerAla: 5.44 ± 0.046	0.662SerCys: 0.662 ± 0.023	3.476SerAsp: 3.476 ± 0.038	3.189SerGlu: 3.189 ± 0.034	2.084SerPhe: 2.084 ± 0.031	5.093SerGly: 5.093 ± 0.049	1.366SerHis: 1.366 ± 0.021	2.509SerIle: 2.509 ± 0.032	1.719SerLys: 1.719 ± 0.029	6.427SerLeu: 6.427 ± 0.059	1.217SerMet: 1.217 ± 0.024	1.635SerAsn: 1.635 ± 0.03	4.208SerPro: 4.208 ± 0.043	2.736SerGln: 2.736 ± 0.036	3.965SerArg: 3.965 ± 0.038	3.751SerSer: 3.751 ± 0.053	3.028SerThr: 3.028 ± 0.034	3.729SerVal: 3.729 ± 0.037	0.933SerTrp: 0.933 ± 0.019	1.377SerTyr: 1.377 ± 0.024	0.0SerXaa: 0.0 ± 0.0
Thr	5.915ThrAla: 5.915 ± 0.061	0.558ThrCys: 0.558 ± 0.017	2.988ThrAsp: 2.988 ± 0.036	2.709ThrGlu: 2.709 ± 0.036	1.893ThrPhe: 1.893 ± 0.026	4.469ThrGly: 4.469 ± 0.055	1.127ThrHis: 1.127 ± 0.021	2.531ThrIle: 2.531 ± 0.037	1.29ThrLys: 1.29 ± 0.027	5.468ThrLeu: 5.468 ± 0.052	0.929ThrMet: 0.929 ± 0.02	1.379ThrAsn: 1.379 ± 0.023	3.993ThrPro: 3.993 ± 0.049	1.822ThrGln: 1.822 ± 0.027	3.052ThrArg: 3.052 ± 0.035	2.954ThrSer: 2.954 ± 0.031	2.902ThrThr: 2.902 ± 0.041	3.58ThrVal: 3.58 ± 0.042	0.718ThrTrp: 0.718 ± 0.019	1.176ThrTyr: 1.176 ± 0.026	0.0ThrXaa: 0.0 ± 0.0
Val	7.384ValAla: 7.384 ± 0.06	0.917ValCys: 0.917 ± 0.024	4.39ValAsp: 4.39 ± 0.045	4.735ValGlu: 4.735 ± 0.045	2.478ValPhe: 2.478 ± 0.034	4.71ValGly: 4.71 ± 0.054	1.373ValHis: 1.373 ± 0.024	3.18ValIle: 3.18 ± 0.035	2.341ValLys: 2.341 ± 0.031	7.13ValLeu: 7.13 ± 0.065	1.453ValMet: 1.453 ± 0.025	1.96ValAsn: 1.96 ± 0.03	2.781ValPro: 2.781 ± 0.031	2.621ValGln: 2.621 ± 0.034	4.782ValArg: 4.782 ± 0.049	4.049ValSer: 4.049 ± 0.039	3.57ValThr: 3.57 ± 0.04	5.447ValVal: 5.447 ± 0.052	1.143ValTrp: 1.143 ± 0.022	1.7ValTyr: 1.7 ± 0.027	0.0ValXaa: 0.0 ± 0.0
Trp	1.191TrpAla: 1.191 ± 0.02	0.192TrpCys: 0.192 ± 0.009	0.836TrpAsp: 0.836 ± 0.017	0.834TrpGlu: 0.834 ± 0.019	0.542TrpPhe: 0.542 ± 0.014	1.013TrpGly: 1.013 ± 0.02	0.349TrpHis: 0.349 ± 0.012	0.763TrpIle: 0.763 ± 0.019	0.707TrpLys: 0.707 ± 0.018	1.879TrpLeu: 1.879 ± 0.032	0.393TrpMet: 0.393 ± 0.014	0.546TrpAsn: 0.546 ± 0.017	0.768TrpPro: 0.768 ± 0.019	0.731TrpGln: 0.731 ± 0.019	1.417TrpArg: 1.417 ± 0.028	1.115TrpSer: 1.115 ± 0.025	0.877TrpThr: 0.877 ± 0.018	0.896TrpVal: 0.896 ± 0.019	0.269TrpTrp: 0.269 ± 0.011	0.34TrpTyr: 0.34 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.419TyrAla: 2.419 ± 0.031	0.364TyrCys: 0.364 ± 0.012	1.667TyrAsp: 1.667 ± 0.029	1.467TyrGlu: 1.467 ± 0.024	1.066TyrPhe: 1.066 ± 0.02	2.14TyrGly: 2.14 ± 0.033	0.645TyrHis: 0.645 ± 0.016	0.736TyrIle: 0.736 ± 0.02	0.635TyrLys: 0.635 ± 0.015	2.822TyrLeu: 2.822 ± 0.035	0.391TyrMet: 0.391 ± 0.013	0.733TyrAsn: 0.733 ± 0.018	1.257TyrPro: 1.257 ± 0.022	1.201TyrGln: 1.201 ± 0.024	2.087TyrArg: 2.087 ± 0.031	1.318TyrSer: 1.318 ± 0.024	1.088TyrThr: 1.088 ± 0.022	1.59TyrVal: 1.59 ± 0.025	0.433TyrTrp: 0.433 ± 0.015	0.844TyrTyr: 0.844 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 6917 proteins (2670640 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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