Amino acid dipepetide frequency for Setaria viridis (Green bristlegrass) (Setaria italica subsp. viridis)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	13.902AlaAla: 13.902 ± 0.051	1.665AlaCys: 1.665 ± 0.009	4.233AlaAsp: 4.233 ± 0.016	5.071AlaGlu: 5.071 ± 0.021	2.953AlaPhe: 2.953 ± 0.013	6.829AlaGly: 6.829 ± 0.025	1.796AlaHis: 1.796 ± 0.011	3.58AlaIle: 3.58 ± 0.016	3.753AlaLys: 3.753 ± 0.018	8.043AlaLeu: 8.043 ± 0.026	2.215AlaMet: 2.215 ± 0.011	2.552AlaAsn: 2.552 ± 0.012	5.3AlaPro: 5.3 ± 0.031	2.533AlaGln: 2.533 ± 0.013	5.568AlaArg: 5.568 ± 0.023	7.615AlaSer: 7.615 ± 0.025	4.698AlaThr: 4.698 ± 0.019	6.577AlaVal: 6.577 ± 0.024	1.021AlaTrp: 1.021 ± 0.008	1.928AlaTyr: 1.928 ± 0.012	0.0AlaXaa: 0.0 ± 0.0
Cys	1.421CysAla: 1.421 ± 0.009	0.643CysCys: 0.643 ± 0.007	0.902CysAsp: 0.902 ± 0.007	0.835CysGlu: 0.835 ± 0.007	0.847CysPhe: 0.847 ± 0.007	1.542CysGly: 1.542 ± 0.011	0.53CysHis: 0.53 ± 0.006	0.934CysIle: 0.934 ± 0.007	1.002CysLys: 1.002 ± 0.01	1.887CysLeu: 1.887 ± 0.012	0.478CysMet: 0.478 ± 0.005	0.745CysAsn: 0.745 ± 0.007	1.07CysPro: 1.07 ± 0.009	0.618CysGln: 0.618 ± 0.006	1.368CysArg: 1.368 ± 0.01	1.964CysSer: 1.964 ± 0.011	0.97CysThr: 0.97 ± 0.008	1.145CysVal: 1.145 ± 0.009	0.288CysTrp: 0.288 ± 0.004	0.545CysTyr: 0.545 ± 0.006	0.0CysXaa: 0.0 ± 0.0
Asp	4.818AspAla: 4.818 ± 0.017	0.907AspCys: 0.907 ± 0.007	4.014AspAsp: 4.014 ± 0.022	3.851AspGlu: 3.851 ± 0.019	1.992AspPhe: 1.992 ± 0.01	4.549AspGly: 4.549 ± 0.017	1.27AspHis: 1.27 ± 0.009	2.643AspIle: 2.643 ± 0.014	2.385AspLys: 2.385 ± 0.011	4.898AspLeu: 4.898 ± 0.021	1.392AspMet: 1.392 ± 0.009	1.756AspAsn: 1.756 ± 0.012	2.773AspPro: 2.773 ± 0.013	1.627AspGln: 1.627 ± 0.012	2.717AspArg: 2.717 ± 0.015	3.725AspSer: 3.725 ± 0.016	2.23AspThr: 2.23 ± 0.011	3.73AspVal: 3.73 ± 0.015	0.699AspTrp: 0.699 ± 0.007	1.396AspTyr: 1.396 ± 0.01	0.0AspXaa: 0.0 ± 0.0
Glu	5.43GluAla: 5.43 ± 0.024	0.889GluCys: 0.889 ± 0.007	3.721GluAsp: 3.721 ± 0.018	5.575GluGlu: 5.575 ± 0.031	1.999GluPhe: 1.999 ± 0.01	3.697GluGly: 3.697 ± 0.015	1.425GluHis: 1.425 ± 0.009	2.912GluIle: 2.912 ± 0.014	3.682GluLys: 3.682 ± 0.019	5.869GluLeu: 5.869 ± 0.023	1.632GluMet: 1.632 ± 0.01	2.232GluAsn: 2.232 ± 0.012	2.437GluPro: 2.437 ± 0.014	2.308GluGln: 2.308 ± 0.014	3.568GluArg: 3.568 ± 0.017	3.792GluSer: 3.792 ± 0.019	2.532GluThr: 2.532 ± 0.014	4.063GluVal: 4.063 ± 0.016	0.722GluTrp: 0.722 ± 0.006	1.449GluTyr: 1.449 ± 0.01	0.0GluXaa: 0.0 ± 0.0
Phe	2.792PheAla: 2.792 ± 0.014	0.804PheCys: 0.804 ± 0.007	2.072PheAsp: 2.072 ± 0.012	1.836PheGlu: 1.836 ± 0.01	1.674PhePhe: 1.674 ± 0.013	2.818PheGly: 2.818 ± 0.016	1.016PheHis: 1.016 ± 0.008	1.61PheIle: 1.61 ± 0.012	1.528PheLys: 1.528 ± 0.009	3.891PheLeu: 3.891 ± 0.018	0.854PheMet: 0.854 ± 0.007	1.281PheAsn: 1.281 ± 0.009	1.886PhePro: 1.886 ± 0.011	1.273PheGln: 1.273 ± 0.008	2.061PheArg: 2.061 ± 0.011	3.271PheSer: 3.271 ± 0.016	1.745PheThr: 1.745 ± 0.01	2.564PheVal: 2.564 ± 0.012	0.518PheTrp: 0.518 ± 0.006	1.053PheTyr: 1.053 ± 0.01	0.0PheXaa: 0.0 ± 0.0
Gly	6.407GlyAla: 6.407 ± 0.025	1.507GlyCys: 1.507 ± 0.01	3.948GlyAsp: 3.948 ± 0.015	3.868GlyGlu: 3.868 ± 0.016	2.788GlyPhe: 2.788 ± 0.016	7.77GlyGly: 7.77 ± 0.043	1.784GlyHis: 1.784 ± 0.011	3.077GlyIle: 3.077 ± 0.014	3.561GlyLys: 3.561 ± 0.017	5.941GlyLeu: 5.941 ± 0.02	1.62GlyMet: 1.62 ± 0.01	2.721GlyAsn: 2.721 ± 0.014	2.983GlyPro: 2.983 ± 0.014	2.182GlyGln: 2.182 ± 0.011	4.907GlyArg: 4.907 ± 0.02	6.266GlySer: 6.266 ± 0.022	3.542GlyThr: 3.542 ± 0.016	4.589GlyVal: 4.589 ± 0.017	1.022GlyTrp: 1.022 ± 0.009	2.039GlyTyr: 2.039 ± 0.015	0.0GlyXaa: 0.0 ± 0.0
His	1.952HisAla: 1.952 ± 0.012	0.565HisCys: 0.565 ± 0.006	1.274HisAsp: 1.274 ± 0.009	1.271HisGlu: 1.271 ± 0.008	0.915HisPhe: 0.915 ± 0.007	2.167HisGly: 2.167 ± 0.012	1.068HisHis: 1.068 ± 0.009	1.078HisIle: 1.078 ± 0.008	1.007HisLys: 1.007 ± 0.007	2.592HisLeu: 2.592 ± 0.014	0.585HisMet: 0.585 ± 0.005	0.807HisAsn: 0.807 ± 0.007	1.609HisPro: 1.609 ± 0.011	1.007HisGln: 1.007 ± 0.008	1.753HisArg: 1.753 ± 0.011	1.782HisSer: 1.782 ± 0.011	0.98HisThr: 0.98 ± 0.008	1.61HisVal: 1.61 ± 0.01	0.313HisTrp: 0.313 ± 0.004	0.65HisTyr: 0.65 ± 0.006	0.0HisXaa: 0.0 ± 0.0
Ile	3.46IleAla: 3.46 ± 0.018	0.978IleCys: 0.978 ± 0.008	2.461IleAsp: 2.461 ± 0.011	2.462IleGlu: 2.462 ± 0.013	1.74IlePhe: 1.74 ± 0.011	2.944IleGly: 2.944 ± 0.015	1.115IleHis: 1.115 ± 0.008	2.202IleIle: 2.202 ± 0.013	2.182IleLys: 2.182 ± 0.011	4.321IleLeu: 4.321 ± 0.019	1.003IleMet: 1.003 ± 0.007	1.636IleAsn: 1.636 ± 0.01	2.481IlePro: 2.481 ± 0.017	1.617IleGln: 1.617 ± 0.01	2.437IleArg: 2.437 ± 0.012	3.814IleSer: 3.814 ± 0.017	2.202IleThr: 2.202 ± 0.012	2.956IleVal: 2.956 ± 0.016	0.61IleTrp: 0.61 ± 0.006	1.207IleTyr: 1.207 ± 0.008	0.0IleXaa: 0.0 ± 0.0
Lys	3.83LysAla: 3.83 ± 0.017	0.833LysCys: 0.833 ± 0.008	2.723LysAsp: 2.723 ± 0.015	3.669LysGlu: 3.669 ± 0.017	1.606LysPhe: 1.606 ± 0.01	3.052LysGly: 3.052 ± 0.015	1.193LysHis: 1.193 ± 0.01	2.461LysIle: 2.461 ± 0.013	3.588LysLys: 3.588 ± 0.02	4.878LysLeu: 4.878 ± 0.02	1.248LysMet: 1.248 ± 0.009	1.933LysAsn: 1.933 ± 0.01	2.347LysPro: 2.347 ± 0.015	1.957LysGln: 1.957 ± 0.013	3.173LysArg: 3.173 ± 0.016	3.438LysSer: 3.438 ± 0.016	2.169LysThr: 2.169 ± 0.012	3.239LysVal: 3.239 ± 0.014	0.608LysTrp: 0.608 ± 0.007	1.31LysTyr: 1.31 ± 0.008	0.0LysXaa: 0.0 ± 0.0
Leu	8.159LeuAla: 8.159 ± 0.025	1.916LeuCys: 1.916 ± 0.011	5.09LeuAsp: 5.09 ± 0.018	5.796LeuGlu: 5.796 ± 0.026	3.385LeuPhe: 3.385 ± 0.016	5.992LeuGly: 5.992 ± 0.018	2.769LeuHis: 2.769 ± 0.016	3.671LeuIle: 3.671 ± 0.016	4.768LeuLys: 4.768 ± 0.021	10.642LeuLeu: 10.642 ± 0.042	2.045LeuMet: 2.045 ± 0.01	3.065LeuAsn: 3.065 ± 0.015	5.984LeuPro: 5.984 ± 0.022	4.179LeuGln: 4.179 ± 0.019	6.396LeuArg: 6.396 ± 0.023	7.852LeuSer: 7.852 ± 0.033	4.19LeuThr: 4.19 ± 0.018	6.503LeuVal: 6.503 ± 0.02	1.165LeuTrp: 1.165 ± 0.009	2.266LeuTyr: 2.266 ± 0.013	0.0LeuXaa: 0.0 ± 0.0
Met	2.608MetAla: 2.608 ± 0.013	0.364MetCys: 0.364 ± 0.004	1.458MetAsp: 1.458 ± 0.009	1.834MetGlu: 1.834 ± 0.01	0.783MetPhe: 0.783 ± 0.007	1.517MetGly: 1.517 ± 0.01	0.594MetHis: 0.594 ± 0.006	0.987MetIle: 0.987 ± 0.007	1.277MetLys: 1.277 ± 0.009	2.285MetLeu: 2.285 ± 0.012	0.665MetMet: 0.665 ± 0.007	0.827MetAsn: 0.827 ± 0.007	1.303MetPro: 1.303 ± 0.01	0.957MetGln: 0.957 ± 0.008	1.367MetArg: 1.367 ± 0.008	1.712MetSer: 1.712 ± 0.009	1.02MetThr: 1.02 ± 0.008	1.667MetVal: 1.667 ± 0.012	0.279MetTrp: 0.279 ± 0.004	0.57MetTyr: 0.57 ± 0.006	0.0MetXaa: 0.0 ± 0.0
Asn	2.596AsnAla: 2.596 ± 0.015	0.734AsnCys: 0.734 ± 0.007	1.688AsnAsp: 1.688 ± 0.01	1.867AsnGlu: 1.867 ± 0.011	1.436AsnPhe: 1.436 ± 0.009	2.795AsnGly: 2.795 ± 0.013	0.889AsnHis: 0.889 ± 0.007	1.948AsnIle: 1.948 ± 0.012	1.817AsnLys: 1.817 ± 0.011	3.677AsnLeu: 3.677 ± 0.024	0.945AsnMet: 0.945 ± 0.007	1.643AsnAsn: 1.643 ± 0.014	1.89AsnPro: 1.89 ± 0.011	1.307AsnGln: 1.307 ± 0.01	1.773AsnArg: 1.773 ± 0.011	2.901AsnSer: 2.901 ± 0.017	1.692AsnThr: 1.692 ± 0.009	2.225AsnVal: 2.225 ± 0.011	0.447AsnTrp: 0.447 ± 0.005	0.973AsnTyr: 0.973 ± 0.008	0.0AsnXaa: 0.0 ± 0.0
Pro	5.865ProAla: 5.865 ± 0.027	1.019ProCys: 1.019 ± 0.008	2.783ProAsp: 2.783 ± 0.015	3.324ProGlu: 3.324 ± 0.015	1.907ProPhe: 1.907 ± 0.01	3.578ProGly: 3.578 ± 0.016	1.284ProHis: 1.284 ± 0.008	1.926ProIle: 1.926 ± 0.011	2.3ProLys: 2.3 ± 0.013	4.677ProLeu: 4.677 ± 0.02	1.124ProMet: 1.124 ± 0.009	1.872ProAsn: 1.872 ± 0.012	6.001ProPro: 6.001 ± 0.045	1.909ProGln: 1.909 ± 0.013	3.602ProArg: 3.602 ± 0.018	5.648ProSer: 5.648 ± 0.025	2.875ProThr: 2.875 ± 0.02	3.585ProVal: 3.585 ± 0.016	0.727ProTrp: 0.727 ± 0.007	1.266ProTyr: 1.266 ± 0.009	0.0ProXaa: 0.0 ± 0.0
Gln	2.747GlnAla: 2.747 ± 0.016	0.625GlnCys: 0.625 ± 0.006	1.676GlnAsp: 1.676 ± 0.01	2.387GlnGlu: 2.387 ± 0.014	1.165GlnPhe: 1.165 ± 0.008	2.25GlnGly: 2.25 ± 0.012	1.032GlnHis: 1.032 ± 0.01	1.571GlnIle: 1.571 ± 0.011	1.894GlnLys: 1.894 ± 0.013	3.566GlnLeu: 3.566 ± 0.016	0.945GlnMet: 0.945 ± 0.008	1.365GlnAsn: 1.365 ± 0.011	2.012GlnPro: 2.012 ± 0.014	2.28GlnGln: 2.28 ± 0.026	2.29GlnArg: 2.29 ± 0.013	2.506GlnSer: 2.506 ± 0.013	1.477GlnThr: 1.477 ± 0.011	2.264GlnVal: 2.264 ± 0.011	0.464GlnTrp: 0.464 ± 0.005	0.892GlnTyr: 0.892 ± 0.008	0.0GlnXaa: 0.0 ± 0.0
Arg	5.279ArgAla: 5.279 ± 0.02	1.366ArgCys: 1.366 ± 0.009	3.021ArgAsp: 3.021 ± 0.015	3.464ArgGlu: 3.464 ± 0.017	2.231ArgPhe: 2.231 ± 0.012	4.368ArgGly: 4.368 ± 0.023	1.723ArgHis: 1.723 ± 0.009	2.639ArgIle: 2.639 ± 0.011	3.38ArgLys: 3.38 ± 0.015	5.995ArgLeu: 5.995 ± 0.023	1.497ArgMet: 1.497 ± 0.009	2.168ArgAsn: 2.168 ± 0.013	3.486ArgPro: 3.486 ± 0.019	2.102ArgGln: 2.102 ± 0.011	6.513ArgArg: 6.513 ± 0.031	5.063ArgSer: 5.063 ± 0.02	2.733ArgThr: 2.733 ± 0.014	3.764ArgVal: 3.764 ± 0.015	1.012ArgTrp: 1.012 ± 0.008	1.567ArgTyr: 1.567 ± 0.009	0.0ArgXaa: 0.0 ± 0.0
Ser	6.719SerAla: 6.719 ± 0.021	1.817SerCys: 1.817 ± 0.011	4.086SerAsp: 4.086 ± 0.017	4.102SerGlu: 4.102 ± 0.019	3.309SerPhe: 3.309 ± 0.015	6.075SerGly: 6.075 ± 0.025	1.822SerHis: 1.822 ± 0.011	3.655SerIle: 3.655 ± 0.015	3.854SerLys: 3.854 ± 0.017	7.843SerLeu: 7.843 ± 0.029	2.026SerMet: 2.026 ± 0.011	3.116SerAsn: 3.116 ± 0.017	5.063SerPro: 5.063 ± 0.028	2.575SerGln: 2.575 ± 0.015	4.893SerArg: 4.893 ± 0.016	10.18SerSer: 10.18 ± 0.041	4.535SerThr: 4.535 ± 0.021	4.95SerVal: 4.95 ± 0.018	1.161SerTrp: 1.161 ± 0.009	2.117SerTyr: 2.117 ± 0.012	0.0SerXaa: 0.0 ± 0.0
Thr	4.417ThrAla: 4.417 ± 0.019	0.969ThrCys: 0.969 ± 0.007	2.319ThrAsp: 2.319 ± 0.011	2.597ThrGlu: 2.597 ± 0.015	1.768ThrPhe: 1.768 ± 0.011	3.515ThrGly: 3.515 ± 0.016	0.962ThrHis: 0.962 ± 0.007	2.222ThrIle: 2.222 ± 0.012	2.202ThrLys: 2.202 ± 0.013	4.264ThrLeu: 4.264 ± 0.016	1.197ThrMet: 1.197 ± 0.007	1.743ThrAsn: 1.743 ± 0.011	2.926ThrPro: 2.926 ± 0.021	1.345ThrGln: 1.345 ± 0.01	2.636ThrArg: 2.636 ± 0.012	4.322ThrSer: 4.322 ± 0.019	2.98ThrThr: 2.98 ± 0.014	3.437ThrVal: 3.437 ± 0.016	0.622ThrTrp: 0.622 ± 0.006	1.241ThrTyr: 1.241 ± 0.01	0.0ThrXaa: 0.0 ± 0.0
Val	6.565ValAla: 6.565 ± 0.021	1.23ValCys: 1.23 ± 0.009	3.786ValAsp: 3.786 ± 0.016	4.048ValGlu: 4.048 ± 0.017	2.452ValPhe: 2.452 ± 0.014	4.322ValGly: 4.322 ± 0.016	1.672ValHis: 1.672 ± 0.01	2.864ValIle: 2.864 ± 0.015	3.123ValLys: 3.123 ± 0.017	6.689ValLeu: 6.689 ± 0.023	1.532ValMet: 1.532 ± 0.01	2.103ValAsn: 2.103 ± 0.01	3.883ValPro: 3.883 ± 0.016	2.317ValGln: 2.317 ± 0.012	3.796ValArg: 3.796 ± 0.018	5.068ValSer: 5.068 ± 0.019	3.272ValThr: 3.272 ± 0.017	5.295ValVal: 5.295 ± 0.023	0.812ValTrp: 0.812 ± 0.007	1.757ValTyr: 1.757 ± 0.011	0.0ValXaa: 0.0 ± 0.0
Trp	0.98TrpAla: 0.98 ± 0.007	0.285TrpCys: 0.285 ± 0.004	0.675TrpAsp: 0.675 ± 0.006	0.737TrpGlu: 0.737 ± 0.007	0.495TrpPhe: 0.495 ± 0.005	0.758TrpGly: 0.758 ± 0.007	0.338TrpHis: 0.338 ± 0.005	0.619TrpIle: 0.619 ± 0.007	0.743TrpLys: 0.743 ± 0.006	1.294TrpLeu: 1.294 ± 0.01	0.371TrpMet: 0.371 ± 0.005	0.588TrpAsn: 0.588 ± 0.006	0.636TrpPro: 0.636 ± 0.006	0.469TrpGln: 0.469 ± 0.005	1.083TrpArg: 1.083 ± 0.009	1.027TrpSer: 1.027 ± 0.009	0.64TrpThr: 0.64 ± 0.006	0.807TrpVal: 0.807 ± 0.008	0.262TrpTrp: 0.262 ± 0.004	0.337TrpTyr: 0.337 ± 0.004	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.886TyrAla: 1.886 ± 0.012	0.617TyrCys: 0.617 ± 0.006	1.441TyrAsp: 1.441 ± 0.01	1.342TyrGlu: 1.342 ± 0.009	1.099TyrPhe: 1.099 ± 0.009	1.987TyrGly: 1.987 ± 0.013	0.699TyrHis: 0.699 ± 0.006	1.226TyrIle: 1.226 ± 0.008	1.212TyrLys: 1.212 ± 0.009	2.581TyrLeu: 2.581 ± 0.015	0.7TyrMet: 0.7 ± 0.007	1.09TyrAsn: 1.09 ± 0.008	1.202TyrPro: 1.202 ± 0.009	0.848TyrGln: 0.848 ± 0.007	1.469TyrArg: 1.469 ± 0.01	1.95TyrSer: 1.95 ± 0.012	1.202TyrThr: 1.202 ± 0.009	1.618TyrVal: 1.618 ± 0.009	0.395TyrTrp: 0.395 ± 0.005	0.906TyrTyr: 0.906 ± 0.009	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 46514 proteins (18246505 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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