Amino acid dipepetide frequency for Buttiauxella agrestis ATCC 33320

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.752AlaAla: 9.752 ± 0.116	1.072AlaCys: 1.072 ± 0.027	4.906AlaAsp: 4.906 ± 0.062	5.509AlaGlu: 5.509 ± 0.064	3.533AlaPhe: 3.533 ± 0.055	7.436AlaGly: 7.436 ± 0.092	1.84AlaHis: 1.84 ± 0.035	5.942AlaIle: 5.942 ± 0.075	3.944AlaLys: 3.944 ± 0.062	11.21AlaLeu: 11.21 ± 0.125	2.93AlaMet: 2.93 ± 0.05	3.278AlaAsn: 3.278 ± 0.062	3.623AlaPro: 3.623 ± 0.062	4.53AlaGln: 4.53 ± 0.068	5.051AlaArg: 5.051 ± 0.056	5.397AlaSer: 5.397 ± 0.061	4.896AlaThr: 4.896 ± 0.073	6.758AlaVal: 6.758 ± 0.082	1.533AlaTrp: 1.533 ± 0.035	1.963AlaTyr: 1.963 ± 0.038	0.0AlaXaa: 0.0 ± 0.0
Cys	0.968CysAla: 0.968 ± 0.027	0.166CysCys: 0.166 ± 0.011	0.597CysAsp: 0.597 ± 0.018	0.618CysGlu: 0.618 ± 0.021	0.419CysPhe: 0.419 ± 0.018	1.039CysGly: 1.039 ± 0.028	0.321CysHis: 0.321 ± 0.015	0.584CysIle: 0.584 ± 0.022	0.345CysLys: 0.345 ± 0.015	1.003CysLeu: 1.003 ± 0.027	0.231CysMet: 0.231 ± 0.013	0.355CysAsn: 0.355 ± 0.016	0.482CysPro: 0.482 ± 0.022	0.465CysGln: 0.465 ± 0.019	0.569CysArg: 0.569 ± 0.022	0.669CysSer: 0.669 ± 0.02	0.47CysThr: 0.47 ± 0.017	0.729CysVal: 0.729 ± 0.024	0.17CysTrp: 0.17 ± 0.012	0.326CysTyr: 0.326 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	5.03AspAla: 5.03 ± 0.07	0.529AspCys: 0.529 ± 0.019	2.877AspAsp: 2.877 ± 0.057	3.679AspGlu: 3.679 ± 0.06	2.115AspPhe: 2.115 ± 0.042	3.882AspGly: 3.882 ± 0.075	0.954AspHis: 0.954 ± 0.031	3.378AspIle: 3.378 ± 0.05	2.563AspLys: 2.563 ± 0.046	4.646AspLeu: 4.646 ± 0.062	1.322AspMet: 1.322 ± 0.03	2.376AspAsn: 2.376 ± 0.05	2.139AspPro: 2.139 ± 0.043	1.634AspGln: 1.634 ± 0.036	2.476AspArg: 2.476 ± 0.044	3.014AspSer: 3.014 ± 0.049	2.576AspThr: 2.576 ± 0.058	3.882AspVal: 3.882 ± 0.055	0.782AspTrp: 0.782 ± 0.028	1.849AspTyr: 1.849 ± 0.04	0.0AspXaa: 0.0 ± 0.0
Glu	5.103GluAla: 5.103 ± 0.071	0.472GluCys: 0.472 ± 0.019	2.433GluAsp: 2.433 ± 0.053	3.319GluGlu: 3.319 ± 0.061	1.988GluPhe: 1.988 ± 0.039	3.576GluGly: 3.576 ± 0.056	1.479GluHis: 1.479 ± 0.035	3.456GluIle: 3.456 ± 0.06	3.221GluLys: 3.221 ± 0.055	6.13GluLeu: 6.13 ± 0.078	1.856GluMet: 1.856 ± 0.037	2.53GluAsn: 2.53 ± 0.043	2.097GluPro: 2.097 ± 0.044	3.451GluGln: 3.451 ± 0.063	3.521GluArg: 3.521 ± 0.059	3.132GluSer: 3.132 ± 0.055	3.023GluThr: 3.023 ± 0.052	3.795GluVal: 3.795 ± 0.067	0.809GluTrp: 0.809 ± 0.026	1.484GluTyr: 1.484 ± 0.03	0.0GluXaa: 0.0 ± 0.0
Phe	3.804PheAla: 3.804 ± 0.059	0.523PheCys: 0.523 ± 0.02	2.361PheAsp: 2.361 ± 0.041	1.898PheGlu: 1.898 ± 0.039	1.76PhePhe: 1.76 ± 0.044	3.373PheGly: 3.373 ± 0.056	0.785PheHis: 0.785 ± 0.025	2.659PheIle: 2.659 ± 0.045	1.428PheLys: 1.428 ± 0.032	3.351PheLeu: 3.351 ± 0.057	1.036PheMet: 1.036 ± 0.028	1.821PheAsn: 1.821 ± 0.042	1.527PhePro: 1.527 ± 0.032	1.13PheGln: 1.13 ± 0.026	1.849PheArg: 1.849 ± 0.037	3.172PheSer: 3.172 ± 0.045	2.428PheThr: 2.428 ± 0.05	2.621PheVal: 2.621 ± 0.047	0.614PheTrp: 0.614 ± 0.021	1.277PheTyr: 1.277 ± 0.031	0.0PheXaa: 0.0 ± 0.0
Gly	6.132GlyAla: 6.132 ± 0.097	1.013GlyCys: 1.013 ± 0.03	3.763GlyAsp: 3.763 ± 0.08	4.538GlyGlu: 4.538 ± 0.062	3.311GlyPhe: 3.311 ± 0.055	5.41GlyGly: 5.41 ± 0.101	1.626GlyHis: 1.626 ± 0.039	5.103GlyIle: 5.103 ± 0.068	4.024GlyLys: 4.024 ± 0.065	7.498GlyLeu: 7.498 ± 0.084	2.408GlyMet: 2.408 ± 0.045	2.937GlyAsn: 2.937 ± 0.071	2.028GlyPro: 2.028 ± 0.039	2.881GlyGln: 2.881 ± 0.048	3.603GlyArg: 3.603 ± 0.057	4.411GlySer: 4.411 ± 0.062	3.842GlyThr: 3.842 ± 0.093	6.062GlyVal: 6.062 ± 0.072	1.272GlyTrp: 1.272 ± 0.032	2.633GlyTyr: 2.633 ± 0.048	0.0GlyXaa: 0.0 ± 0.0
His	1.964HisAla: 1.964 ± 0.039	0.315HisCys: 0.315 ± 0.014	1.2HisAsp: 1.2 ± 0.035	1.164HisGlu: 1.164 ± 0.027	1.105HisPhe: 1.105 ± 0.029	1.767HisGly: 1.767 ± 0.037	0.769HisHis: 0.769 ± 0.024	1.312HisIle: 1.312 ± 0.031	0.807HisLys: 0.807 ± 0.024	2.267HisLeu: 2.267 ± 0.042	0.545HisMet: 0.545 ± 0.02	0.888HisAsn: 0.888 ± 0.026	1.319HisPro: 1.319 ± 0.036	1.163HisGln: 1.163 ± 0.03	1.198HisArg: 1.198 ± 0.033	1.314HisSer: 1.314 ± 0.031	1.033HisThr: 1.033 ± 0.028	1.32HisVal: 1.32 ± 0.03	0.395HisTrp: 0.395 ± 0.016	0.854HisTyr: 0.854 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	6.433IleAla: 6.433 ± 0.081	0.712IleCys: 0.712 ± 0.021	3.535IleAsp: 3.535 ± 0.049	3.43IleGlu: 3.43 ± 0.052	2.187IlePhe: 2.187 ± 0.048	4.787IleGly: 4.787 ± 0.079	1.209IleHis: 1.209 ± 0.034	3.495IleIle: 3.495 ± 0.063	2.473IleLys: 2.473 ± 0.047	5.096IleLeu: 5.096 ± 0.084	1.32IleMet: 1.32 ± 0.034	2.825IleAsn: 2.825 ± 0.056	2.815IlePro: 2.815 ± 0.051	1.873IleGln: 1.873 ± 0.041	2.807IleArg: 2.807 ± 0.046	4.094IleSer: 4.094 ± 0.058	3.753IleThr: 3.753 ± 0.068	4.086IleVal: 4.086 ± 0.051	0.731IleTrp: 0.731 ± 0.025	1.628IleTyr: 1.628 ± 0.038	0.0IleXaa: 0.0 ± 0.0
Lys	4.16LysAla: 4.16 ± 0.058	0.264LysCys: 0.264 ± 0.014	2.17LysAsp: 2.17 ± 0.049	2.499LysGlu: 2.499 ± 0.045	1.26LysPhe: 1.26 ± 0.032	2.953LysGly: 2.953 ± 0.051	0.935LysHis: 0.935 ± 0.027	2.504LysIle: 2.504 ± 0.047	2.161LysLys: 2.161 ± 0.047	4.527LysLeu: 4.527 ± 0.066	1.349LysMet: 1.349 ± 0.034	1.82LysAsn: 1.82 ± 0.037	2.276LysPro: 2.276 ± 0.043	2.1LysGln: 2.1 ± 0.04	2.507LysArg: 2.507 ± 0.047	2.46LysSer: 2.46 ± 0.047	2.666LysThr: 2.666 ± 0.052	3.114LysVal: 3.114 ± 0.048	0.484LysTrp: 0.484 ± 0.019	1.108LysTyr: 1.108 ± 0.033	0.0LysXaa: 0.0 ± 0.0
Leu	11.261LeuAla: 11.261 ± 0.123	1.235LeuCys: 1.235 ± 0.028	5.421LeuAsp: 5.421 ± 0.073	5.637LeuGlu: 5.637 ± 0.081	4.218LeuPhe: 4.218 ± 0.071	7.396LeuGly: 7.396 ± 0.079	2.302LeuHis: 2.302 ± 0.046	5.854LeuIle: 5.854 ± 0.081	4.678LeuLys: 4.678 ± 0.066	11.667LeuLeu: 11.667 ± 0.153	3.04LeuMet: 3.04 ± 0.052	4.4LeuAsn: 4.4 ± 0.065	5.64LeuPro: 5.64 ± 0.073	4.138LeuGln: 4.138 ± 0.065	5.758LeuArg: 5.758 ± 0.081	7.167LeuSer: 7.167 ± 0.08	6.205LeuThr: 6.205 ± 0.075	7.349LeuVal: 7.349 ± 0.078	1.371LeuTrp: 1.371 ± 0.035	2.54LeuTyr: 2.54 ± 0.04	0.0LeuXaa: 0.0 ± 0.0
Met	2.84MetAla: 2.84 ± 0.046	0.211MetCys: 0.211 ± 0.011	1.227MetAsp: 1.227 ± 0.03	1.299MetGlu: 1.299 ± 0.029	0.974MetPhe: 0.974 ± 0.026	1.969MetGly: 1.969 ± 0.041	0.545MetHis: 0.545 ± 0.018	1.514MetIle: 1.514 ± 0.035	1.481MetLys: 1.481 ± 0.035	3.217MetLeu: 3.217 ± 0.057	0.912MetMet: 0.912 ± 0.026	1.112MetAsn: 1.112 ± 0.028	1.379MetPro: 1.379 ± 0.032	1.189MetGln: 1.189 ± 0.028	1.477MetArg: 1.477 ± 0.029	1.955MetSer: 1.955 ± 0.045	1.766MetThr: 1.766 ± 0.036	2.13MetVal: 2.13 ± 0.039	0.285MetTrp: 0.285 ± 0.018	0.548MetTyr: 0.548 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.564AsnAla: 3.564 ± 0.053	0.365AsnCys: 0.365 ± 0.016	2.165AsnAsp: 2.165 ± 0.054	2.062AsnGlu: 2.062 ± 0.041	1.435AsnPhe: 1.435 ± 0.037	3.226AsnGly: 3.226 ± 0.082	0.922AsnHis: 0.922 ± 0.026	2.463AsnIle: 2.463 ± 0.047	1.676AsnLys: 1.676 ± 0.043	3.713AsnLeu: 3.713 ± 0.046	1.006AsnMet: 1.006 ± 0.029	1.704AsnAsn: 1.704 ± 0.045	2.248AsnPro: 2.248 ± 0.044	1.737AsnGln: 1.737 ± 0.037	2.03AsnArg: 2.03 ± 0.039	2.318AsnSer: 2.318 ± 0.046	2.132AsnThr: 2.132 ± 0.046	2.711AsnVal: 2.711 ± 0.054	0.61AsnTrp: 0.61 ± 0.022	1.272AsnTyr: 1.272 ± 0.034	0.0AsnXaa: 0.0 ± 0.0
Pro	4.409ProAla: 4.409 ± 0.063	0.353ProCys: 0.353 ± 0.015	2.656ProAsp: 2.656 ± 0.043	3.461ProGlu: 3.461 ± 0.049	1.9ProPhe: 1.9 ± 0.038	3.37ProGly: 3.37 ± 0.053	1.031ProHis: 1.031 ± 0.028	2.074ProIle: 2.074 ± 0.041	1.603ProLys: 1.603 ± 0.041	5.039ProLeu: 5.039 ± 0.069	1.167ProMet: 1.167 ± 0.033	1.409ProAsn: 1.409 ± 0.033	1.619ProPro: 1.619 ± 0.038	2.205ProGln: 2.205 ± 0.045	1.874ProArg: 1.874 ± 0.04	2.103ProSer: 2.103 ± 0.043	2.244ProThr: 2.244 ± 0.052	3.922ProVal: 3.922 ± 0.054	0.734ProTrp: 0.734 ± 0.025	1.169ProTyr: 1.169 ± 0.028	0.0ProXaa: 0.0 ± 0.0
Gln	4.455GlnAla: 4.455 ± 0.069	0.362GlnCys: 0.362 ± 0.016	1.851GlnAsp: 1.851 ± 0.041	2.167GlnGlu: 2.167 ± 0.046	1.571GlnPhe: 1.571 ± 0.034	3.082GlnGly: 3.082 ± 0.046	1.266GlnHis: 1.266 ± 0.032	2.414GlnIle: 2.414 ± 0.04	1.945GlnLys: 1.945 ± 0.042	5.023GlnLeu: 5.023 ± 0.073	1.212GlnMet: 1.212 ± 0.028	1.603GlnAsn: 1.603 ± 0.03	2.195GlnPro: 2.195 ± 0.044	3.376GlnGln: 3.376 ± 0.066	2.872GlnArg: 2.872 ± 0.055	2.381GlnSer: 2.381 ± 0.044	2.324GlnThr: 2.324 ± 0.044	2.945GlnVal: 2.945 ± 0.051	0.705GlnTrp: 0.705 ± 0.025	1.183GlnTyr: 1.183 ± 0.032	0.0GlnXaa: 0.0 ± 0.0
Arg	4.224ArgAla: 4.224 ± 0.061	0.567ArgCys: 0.567 ± 0.022	2.783ArgAsp: 2.783 ± 0.052	3.631ArgGlu: 3.631 ± 0.067	2.462ArgPhe: 2.462 ± 0.042	3.234ArgGly: 3.234 ± 0.046	1.428ArgHis: 1.428 ± 0.036	3.259ArgIle: 3.259 ± 0.054	2.337ArgLys: 2.337 ± 0.048	6.012ArgLeu: 6.012 ± 0.087	1.567ArgMet: 1.567 ± 0.033	2.037ArgAsn: 2.037 ± 0.036	2.076ArgPro: 2.076 ± 0.038	2.724ArgGln: 2.724 ± 0.049	3.132ArgArg: 3.132 ± 0.065	2.703ArgSer: 2.703 ± 0.046	2.456ArgThr: 2.456 ± 0.042	3.751ArgVal: 3.751 ± 0.047	0.901ArgTrp: 0.901 ± 0.029	2.075ArgTyr: 2.075 ± 0.046	0.0ArgXaa: 0.0 ± 0.0
Ser	5.509SerAla: 5.509 ± 0.067	0.552SerCys: 0.552 ± 0.023	3.101SerAsp: 3.101 ± 0.048	3.314SerGlu: 3.314 ± 0.048	2.444SerPhe: 2.444 ± 0.045	5.325SerGly: 5.325 ± 0.069	1.533SerHis: 1.533 ± 0.031	3.189SerIle: 3.189 ± 0.054	2.166SerLys: 2.166 ± 0.043	6.756SerLeu: 6.756 ± 0.081	1.561SerMet: 1.561 ± 0.04	2.097SerAsn: 2.097 ± 0.045	2.612SerPro: 2.612 ± 0.045	2.738SerGln: 2.738 ± 0.046	3.296SerArg: 3.296 ± 0.05	3.61SerSer: 3.61 ± 0.057	3.184SerThr: 3.184 ± 0.049	4.328SerVal: 4.328 ± 0.06	0.975SerTrp: 0.975 ± 0.032	1.721SerTyr: 1.721 ± 0.036	0.0SerXaa: 0.0 ± 0.0
Thr	5.073ThrAla: 5.073 ± 0.078	0.495ThrCys: 0.495 ± 0.021	2.728ThrAsp: 2.728 ± 0.055	2.714ThrGlu: 2.714 ± 0.044	2.107ThrPhe: 2.107 ± 0.043	4.447ThrGly: 4.447 ± 0.084	1.253ThrHis: 1.253 ± 0.032	3.047ThrIle: 3.047 ± 0.065	1.697ThrLys: 1.697 ± 0.036	7.29ThrLeu: 7.29 ± 0.077	1.219ThrMet: 1.219 ± 0.028	1.747ThrAsn: 1.747 ± 0.045	3.238ThrPro: 3.238 ± 0.06	2.365ThrGln: 2.365 ± 0.045	2.973ThrArg: 2.973 ± 0.051	2.937ThrSer: 2.937 ± 0.057	3.009ThrThr: 3.009 ± 0.067	4.087ThrVal: 4.087 ± 0.086	0.841ThrTrp: 0.841 ± 0.022	1.236ThrTyr: 1.236 ± 0.034	0.0ThrXaa: 0.0 ± 0.0
Val	7.064ValAla: 7.064 ± 0.08	0.781ValCys: 0.781 ± 0.024	3.751ValAsp: 3.751 ± 0.059	4.069ValGlu: 4.069 ± 0.059	2.7ValPhe: 2.7 ± 0.053	5.083ValGly: 5.083 ± 0.072	1.315ValHis: 1.315 ± 0.032	4.777ValIle: 4.777 ± 0.068	3.23ValLys: 3.23 ± 0.056	7.54ValLeu: 7.54 ± 0.082	2.251ValMet: 2.251 ± 0.046	2.84ValAsn: 2.84 ± 0.049	3.012ValPro: 3.012 ± 0.044	2.449ValGln: 2.449 ± 0.047	3.591ValArg: 3.591 ± 0.061	4.598ValSer: 4.598 ± 0.055	4.423ValThr: 4.423 ± 0.088	5.787ValVal: 5.787 ± 0.077	0.983ValTrp: 0.983 ± 0.028	1.746ValTyr: 1.746 ± 0.037	0.0ValXaa: 0.0 ± 0.0
Trp	0.997TrpAla: 0.997 ± 0.027	0.169TrpCys: 0.169 ± 0.011	0.636TrpAsp: 0.636 ± 0.023	0.609TrpGlu: 0.609 ± 0.023	0.712TrpPhe: 0.712 ± 0.025	0.907TrpGly: 0.907 ± 0.03	0.465TrpHis: 0.465 ± 0.017	0.771TrpIle: 0.771 ± 0.023	0.545TrpLys: 0.545 ± 0.021	2.196TrpLeu: 2.196 ± 0.045	0.477TrpMet: 0.477 ± 0.018	0.543TrpAsn: 0.543 ± 0.022	0.648TrpPro: 0.648 ± 0.021	1.16TrpGln: 1.16 ± 0.034	1.014TrpArg: 1.014 ± 0.031	0.825TrpSer: 0.825 ± 0.027	0.563TrpThr: 0.563 ± 0.019	0.967TrpVal: 0.967 ± 0.025	0.236TrpTrp: 0.236 ± 0.014	0.413TrpTyr: 0.413 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.361TyrAla: 2.361 ± 0.04	0.37TyrCys: 0.37 ± 0.017	1.542TyrAsp: 1.542 ± 0.037	1.255TyrGlu: 1.255 ± 0.031	1.217TyrPhe: 1.217 ± 0.029	2.233TyrGly: 2.233 ± 0.046	0.721TyrHis: 0.721 ± 0.024	1.497TyrIle: 1.497 ± 0.038	0.991TyrLys: 0.991 ± 0.03	3.097TyrLeu: 3.097 ± 0.042	0.619TyrMet: 0.619 ± 0.022	1.036TyrAsn: 1.036 ± 0.032	1.372TyrPro: 1.372 ± 0.029	1.622TyrGln: 1.622 ± 0.043	1.761TyrArg: 1.761 ± 0.04	1.751TyrSer: 1.751 ± 0.04	1.507TyrThr: 1.507 ± 0.044	1.649TyrVal: 1.649 ± 0.037	0.422TyrTrp: 0.422 ± 0.017	0.902TyrTyr: 0.902 ± 0.027	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4332 proteins (1401234 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---