Amino acid dipepetide frequency for Aquisalimonas asiatica

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	14.094AlaAla: 14.094 ± 0.155	1.121AlaCys: 1.121 ± 0.036	7.285AlaAsp: 7.285 ± 0.093	7.392AlaGlu: 7.392 ± 0.097	4.028AlaPhe: 4.028 ± 0.061	10.558AlaGly: 10.558 ± 0.156	2.36AlaHis: 2.36 ± 0.046	4.998AlaIle: 4.998 ± 0.072	1.779AlaLys: 1.779 ± 0.05	13.294AlaLeu: 13.294 ± 0.128	3.334AlaMet: 3.334 ± 0.054	2.326AlaAsn: 2.326 ± 0.047	4.842AlaPro: 4.842 ± 0.076	3.406AlaGln: 3.406 ± 0.054	8.803AlaArg: 8.803 ± 0.099	5.63AlaSer: 5.63 ± 0.074	5.49AlaThr: 5.49 ± 0.07	9.201AlaVal: 9.201 ± 0.115	1.673AlaTrp: 1.673 ± 0.043	2.514AlaTyr: 2.514 ± 0.045	0.0AlaXaa: 0.0 ± 0.0
Cys	0.9CysAla: 0.9 ± 0.028	0.121CysCys: 0.121 ± 0.011	0.495CysAsp: 0.495 ± 0.022	0.483CysGlu: 0.483 ± 0.018	0.297CysPhe: 0.297 ± 0.015	0.888CysGly: 0.888 ± 0.032	0.275CysHis: 0.275 ± 0.017	0.377CysIle: 0.377 ± 0.018	0.142CysLys: 0.142 ± 0.01	0.83CysLeu: 0.83 ± 0.026	0.189CysMet: 0.189 ± 0.014	0.211CysAsn: 0.211 ± 0.012	0.496CysPro: 0.496 ± 0.02	0.266CysGln: 0.266 ± 0.014	0.687CysArg: 0.687 ± 0.029	0.464CysSer: 0.464 ± 0.02	0.451CysThr: 0.451 ± 0.02	0.602CysVal: 0.602 ± 0.023	0.136CysTrp: 0.136 ± 0.011	0.235CysTyr: 0.235 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	8.155AspAla: 8.155 ± 0.098	0.48AspCys: 0.48 ± 0.022	5.061AspAsp: 5.061 ± 0.089	4.368AspGlu: 4.368 ± 0.073	1.979AspPhe: 1.979 ± 0.045	6.184AspGly: 6.184 ± 0.079	1.72AspHis: 1.72 ± 0.044	2.646AspIle: 2.646 ± 0.051	1.15AspLys: 1.15 ± 0.036	6.026AspLeu: 6.026 ± 0.071	1.526AspMet: 1.526 ± 0.03	1.576AspAsn: 1.576 ± 0.043	3.624AspPro: 3.624 ± 0.058	2.247AspGln: 2.247 ± 0.039	4.869AspArg: 4.869 ± 0.071	2.813AspSer: 2.813 ± 0.056	3.475AspThr: 3.475 ± 0.058	4.898AspVal: 4.898 ± 0.077	1.103AspTrp: 1.103 ± 0.032	1.738AspTyr: 1.738 ± 0.038	0.0AspXaa: 0.0 ± 0.0
Glu	7.868GluAla: 7.868 ± 0.095	0.396GluCys: 0.396 ± 0.018	3.547GluAsp: 3.547 ± 0.063	4.058GluGlu: 4.058 ± 0.078	1.708GluPhe: 1.708 ± 0.046	4.665GluGly: 4.665 ± 0.078	1.805GluHis: 1.805 ± 0.046	2.726GluIle: 2.726 ± 0.056	1.438GluLys: 1.438 ± 0.044	6.509GluLeu: 6.509 ± 0.081	1.47GluMet: 1.47 ± 0.038	1.56GluAsn: 1.56 ± 0.035	3.471GluPro: 3.471 ± 0.069	3.428GluGln: 3.428 ± 0.054	6.626GluArg: 6.626 ± 0.083	3.145GluSer: 3.145 ± 0.049	3.74GluThr: 3.74 ± 0.063	4.366GluVal: 4.366 ± 0.069	0.889GluTrp: 0.889 ± 0.031	1.319GluTyr: 1.319 ± 0.036	0.0GluXaa: 0.0 ± 0.0
Phe	3.456PheAla: 3.456 ± 0.06	0.336PheCys: 0.336 ± 0.016	2.327PheAsp: 2.327 ± 0.049	2.01PheGlu: 2.01 ± 0.045	1.321PhePhe: 1.321 ± 0.035	3.299PheGly: 3.299 ± 0.063	0.861PheHis: 0.861 ± 0.026	1.464PheIle: 1.464 ± 0.04	0.643PheLys: 0.643 ± 0.024	3.266PheLeu: 3.266 ± 0.062	0.858PheMet: 0.858 ± 0.029	0.963PheAsn: 0.963 ± 0.029	1.541PhePro: 1.541 ± 0.032	1.24PheGln: 1.24 ± 0.034	2.54PheArg: 2.54 ± 0.051	1.931PheSer: 1.931 ± 0.045	1.841PheThr: 1.841 ± 0.037	2.46PheVal: 2.46 ± 0.048	0.515PheTrp: 0.515 ± 0.024	0.856PheTyr: 0.856 ± 0.026	0.0PheXaa: 0.0 ± 0.0
Gly	8.738GlyAla: 8.738 ± 0.136	0.912GlyCys: 0.912 ± 0.026	5.799GlyAsp: 5.799 ± 0.096	5.832GlyGlu: 5.832 ± 0.081	3.309GlyPhe: 3.309 ± 0.06	7.59GlyGly: 7.59 ± 0.129	2.167GlyHis: 2.167 ± 0.041	4.149GlyIle: 4.149 ± 0.072	2.13GlyLys: 2.13 ± 0.04	9.139GlyLeu: 9.139 ± 0.096	2.516GlyMet: 2.516 ± 0.046	2.154GlyAsn: 2.154 ± 0.046	3.235GlyPro: 3.235 ± 0.054	3.043GlyGln: 3.043 ± 0.049	6.529GlyArg: 6.529 ± 0.078	4.516GlySer: 4.516 ± 0.086	4.441GlyThr: 4.441 ± 0.069	7.273GlyVal: 7.273 ± 0.091	1.463GlyTrp: 1.463 ± 0.037	2.473GlyTyr: 2.473 ± 0.048	0.0GlyXaa: 0.0 ± 0.0
His	2.693HisAla: 2.693 ± 0.05	0.262HisCys: 0.262 ± 0.014	1.563HisAsp: 1.563 ± 0.038	1.272HisGlu: 1.272 ± 0.036	0.825HisPhe: 0.825 ± 0.026	2.53HisGly: 2.53 ± 0.047	0.764HisHis: 0.764 ± 0.028	0.879HisIle: 0.879 ± 0.028	0.385HisLys: 0.385 ± 0.019	2.453HisLeu: 2.453 ± 0.048	0.583HisMet: 0.583 ± 0.021	0.593HisAsn: 0.593 ± 0.021	1.54HisPro: 1.54 ± 0.04	0.83HisGln: 0.83 ± 0.022	1.95HisArg: 1.95 ± 0.041	0.999HisSer: 0.999 ± 0.026	1.125HisThr: 1.125 ± 0.034	1.673HisVal: 1.673 ± 0.034	0.478HisTrp: 0.478 ± 0.021	0.715HisTyr: 0.715 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	5.282IleAla: 5.282 ± 0.074	0.377IleCys: 0.377 ± 0.017	2.953IleAsp: 2.953 ± 0.049	2.749IleGlu: 2.749 ± 0.05	1.206IlePhe: 1.206 ± 0.039	4.11IleGly: 4.11 ± 0.067	1.147IleHis: 1.147 ± 0.03	1.96IleIle: 1.96 ± 0.047	0.939IleLys: 0.939 ± 0.031	3.706IleLeu: 3.706 ± 0.066	0.963IleMet: 0.963 ± 0.028	1.432IleAsn: 1.432 ± 0.04	2.273IlePro: 2.273 ± 0.048	1.475IleGln: 1.475 ± 0.035	3.415IleArg: 3.415 ± 0.048	2.225IleSer: 2.225 ± 0.043	2.569IleThr: 2.569 ± 0.051	3.078IleVal: 3.078 ± 0.064	0.473IleTrp: 0.473 ± 0.019	0.99IleTyr: 0.99 ± 0.028	0.0IleXaa: 0.0 ± 0.0
Lys	2.355LysAla: 2.355 ± 0.058	0.128LysCys: 0.128 ± 0.011	1.185LysAsp: 1.185 ± 0.036	1.237LysGlu: 1.237 ± 0.039	0.437LysPhe: 0.437 ± 0.021	1.695LysGly: 1.695 ± 0.046	0.51LysHis: 0.51 ± 0.025	0.739LysIle: 0.739 ± 0.027	0.676LysLys: 0.676 ± 0.034	1.864LysLeu: 1.864 ± 0.047	0.39LysMet: 0.39 ± 0.018	0.478LysAsn: 0.478 ± 0.021	1.136LysPro: 1.136 ± 0.033	0.836LysGln: 0.836 ± 0.031	1.774LysArg: 1.774 ± 0.051	1.018LysSer: 1.018 ± 0.03	1.161LysThr: 1.161 ± 0.035	1.496LysVal: 1.496 ± 0.044	0.216LysTrp: 0.216 ± 0.013	0.44LysTyr: 0.44 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	12.778LeuAla: 12.778 ± 0.123	0.965LeuCys: 0.965 ± 0.03	7.066LeuAsp: 7.066 ± 0.085	7.027LeuGlu: 7.027 ± 0.083	3.739LeuPhe: 3.739 ± 0.062	8.612LeuGly: 8.612 ± 0.095	2.336LeuHis: 2.336 ± 0.048	4.362LeuIle: 4.362 ± 0.061	2.219LeuLys: 2.219 ± 0.055	11.098LeuLeu: 11.098 ± 0.134	2.364LeuMet: 2.364 ± 0.045	2.572LeuAsn: 2.572 ± 0.047	5.731LeuPro: 5.731 ± 0.08	3.803LeuGln: 3.803 ± 0.063	8.114LeuArg: 8.114 ± 0.101	5.479LeuSer: 5.479 ± 0.072	5.438LeuThr: 5.438 ± 0.072	7.966LeuVal: 7.966 ± 0.089	1.306LeuTrp: 1.306 ± 0.044	2.219LeuTyr: 2.219 ± 0.043	0.0LeuXaa: 0.0 ± 0.0
Met	3.162MetAla: 3.162 ± 0.053	0.151MetCys: 0.151 ± 0.011	1.66MetAsp: 1.66 ± 0.039	1.579MetGlu: 1.579 ± 0.033	0.626MetPhe: 0.626 ± 0.026	2.006MetGly: 2.006 ± 0.044	0.522MetHis: 0.522 ± 0.021	1.062MetIle: 1.062 ± 0.031	0.678MetLys: 0.678 ± 0.024	2.507MetLeu: 2.507 ± 0.054	0.549MetMet: 0.549 ± 0.023	0.759MetAsn: 0.759 ± 0.025	1.363MetPro: 1.363 ± 0.034	0.949MetGln: 0.949 ± 0.03	1.769MetArg: 1.769 ± 0.036	1.399MetSer: 1.399 ± 0.035	1.731MetThr: 1.731 ± 0.04	1.851MetVal: 1.851 ± 0.042	0.204MetTrp: 0.204 ± 0.011	0.382MetTyr: 0.382 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	2.822AsnAla: 2.822 ± 0.05	0.208AsnCys: 0.208 ± 0.014	1.461AsnAsp: 1.461 ± 0.04	1.346AsnGlu: 1.346 ± 0.034	0.729AsnPhe: 0.729 ± 0.027	2.211AsnGly: 2.211 ± 0.046	0.615AsnHis: 0.615 ± 0.024	1.161AsnIle: 1.161 ± 0.035	0.483AsnLys: 0.483 ± 0.02	2.452AsnLeu: 2.452 ± 0.047	0.588AsnMet: 0.588 ± 0.021	0.665AsnAsn: 0.665 ± 0.025	1.7AsnPro: 1.7 ± 0.037	0.921AsnGln: 0.921 ± 0.027	2.017AsnArg: 2.017 ± 0.042	1.026AsnSer: 1.026 ± 0.033	1.366AsnThr: 1.366 ± 0.039	1.91AsnVal: 1.91 ± 0.05	0.392AsnTrp: 0.392 ± 0.019	0.615AsnTyr: 0.615 ± 0.024	0.0AsnXaa: 0.0 ± 0.0
Pro	5.562ProAla: 5.562 ± 0.071	0.328ProCys: 0.328 ± 0.019	4.33ProAsp: 4.33 ± 0.064	4.587ProGlu: 4.587 ± 0.081	1.697ProPhe: 1.697 ± 0.042	4.916ProGly: 4.916 ± 0.075	1.031ProHis: 1.031 ± 0.03	1.698ProIle: 1.698 ± 0.034	0.879ProLys: 0.879 ± 0.031	4.935ProLeu: 4.935 ± 0.07	1.25ProMet: 1.25 ± 0.03	1.045ProAsn: 1.045 ± 0.029	2.433ProPro: 2.433 ± 0.053	1.518ProGln: 1.518 ± 0.032	3.241ProArg: 3.241 ± 0.057	2.23ProSer: 2.23 ± 0.046	2.08ProThr: 2.08 ± 0.044	4.56ProVal: 4.56 ± 0.064	0.897ProTrp: 0.897 ± 0.031	1.143ProTyr: 1.143 ± 0.03	0.001ProXaa: 0.001 ± 0.001
Gln	4.586GlnAla: 4.586 ± 0.069	0.241GlnCys: 0.241 ± 0.014	1.973GlnAsp: 1.973 ± 0.036	2.193GlnGlu: 2.193 ± 0.052	1.109GlnPhe: 1.109 ± 0.03	3.015GlnGly: 3.015 ± 0.053	0.86GlnHis: 0.86 ± 0.028	1.377GlnIle: 1.377 ± 0.038	0.691GlnLys: 0.691 ± 0.031	3.655GlnLeu: 3.655 ± 0.063	0.785GlnMet: 0.785 ± 0.027	0.713GlnAsn: 0.713 ± 0.027	1.994GlnPro: 1.994 ± 0.047	1.782GlnGln: 1.782 ± 0.048	3.483GlnArg: 3.483 ± 0.058	1.774GlnSer: 1.774 ± 0.04	1.691GlnThr: 1.691 ± 0.036	2.847GlnVal: 2.847 ± 0.055	0.576GlnTrp: 0.576 ± 0.022	0.814GlnTyr: 0.814 ± 0.026	0.0GlnXaa: 0.0 ± 0.0
Arg	7.661ArgAla: 7.661 ± 0.085	0.638ArgCys: 0.638 ± 0.024	5.174ArgAsp: 5.174 ± 0.064	5.719ArgGlu: 5.719 ± 0.09	3.116ArgPhe: 3.116 ± 0.056	5.38ArgGly: 5.38 ± 0.064	2.244ArgHis: 2.244 ± 0.041	3.885ArgIle: 3.885 ± 0.058	1.775ArgLys: 1.775 ± 0.05	9.155ArgLeu: 9.155 ± 0.094	2.155ArgMet: 2.155 ± 0.048	2.087ArgAsn: 2.087 ± 0.043	3.616ArgPro: 3.616 ± 0.049	3.301ArgGln: 3.301 ± 0.054	6.971ArgArg: 6.971 ± 0.103	3.748ArgSer: 3.748 ± 0.065	3.573ArgThr: 3.573 ± 0.059	5.992ArgVal: 5.992 ± 0.069	1.219ArgTrp: 1.219 ± 0.035	2.276ArgTyr: 2.276 ± 0.049	0.0ArgXaa: 0.0 ± 0.0
Ser	5.316SerAla: 5.316 ± 0.076	0.36SerCys: 0.36 ± 0.019	3.144SerAsp: 3.144 ± 0.059	2.998SerGlu: 2.998 ± 0.058	1.603SerPhe: 1.603 ± 0.031	5.474SerGly: 5.474 ± 0.07	1.083SerHis: 1.083 ± 0.031	2.147SerIle: 2.147 ± 0.047	0.888SerLys: 0.888 ± 0.035	5.254SerLeu: 5.254 ± 0.076	1.389SerMet: 1.389 ± 0.038	1.25SerAsn: 1.25 ± 0.035	2.534SerPro: 2.534 ± 0.046	1.584SerGln: 1.584 ± 0.037	3.921SerArg: 3.921 ± 0.058	2.595SerSer: 2.595 ± 0.05	2.414SerThr: 2.414 ± 0.048	3.904SerVal: 3.904 ± 0.058	0.669SerTrp: 0.669 ± 0.024	1.084SerTyr: 1.084 ± 0.026	0.0SerXaa: 0.0 ± 0.0
Thr	5.973ThrAla: 5.973 ± 0.093	0.415ThrCys: 0.415 ± 0.018	3.096ThrAsp: 3.096 ± 0.053	2.874ThrGlu: 2.874 ± 0.046	1.726ThrPhe: 1.726 ± 0.038	5.228ThrGly: 5.228 ± 0.071	1.04ThrHis: 1.04 ± 0.031	2.265ThrIle: 2.265 ± 0.049	0.757ThrLys: 0.757 ± 0.026	6.127ThrLeu: 6.127 ± 0.073	1.155ThrMet: 1.155 ± 0.033	1.142ThrAsn: 1.142 ± 0.032	3.185ThrPro: 3.185 ± 0.046	1.462ThrGln: 1.462 ± 0.04	3.753ThrArg: 3.753 ± 0.056	2.415ThrSer: 2.415 ± 0.045	2.741ThrThr: 2.741 ± 0.056	4.64ThrVal: 4.64 ± 0.063	0.71ThrTrp: 0.71 ± 0.027	1.136ThrTyr: 1.136 ± 0.031	0.0ThrXaa: 0.0 ± 0.0
Val	9.105ValAla: 9.105 ± 0.107	0.691ValCys: 0.691 ± 0.027	5.3ValAsp: 5.3 ± 0.074	4.918ValGlu: 4.918 ± 0.079	2.769ValPhe: 2.769 ± 0.052	5.869ValGly: 5.869 ± 0.078	1.742ValHis: 1.742 ± 0.035	3.912ValIle: 3.912 ± 0.06	1.414ValLys: 1.414 ± 0.041	8.218ValLeu: 8.218 ± 0.097	1.966ValMet: 1.966 ± 0.046	2.14ValAsn: 2.14 ± 0.05	3.751ValPro: 3.751 ± 0.061	2.314ValGln: 2.314 ± 0.042	5.728ValArg: 5.728 ± 0.076	4.2ValSer: 4.2 ± 0.05	4.601ValThr: 4.601 ± 0.075	6.533ValVal: 6.533 ± 0.09	0.918ValTrp: 0.918 ± 0.029	1.746ValTyr: 1.746 ± 0.041	0.0ValXaa: 0.0 ± 0.0
Trp	1.246TrpAla: 1.246 ± 0.032	0.15TrpCys: 0.15 ± 0.011	0.772TrpAsp: 0.772 ± 0.029	0.807TrpGlu: 0.807 ± 0.026	0.593TrpPhe: 0.593 ± 0.024	0.999TrpGly: 0.999 ± 0.031	0.391TrpHis: 0.391 ± 0.017	0.626TrpIle: 0.626 ± 0.022	0.275TrpLys: 0.275 ± 0.014	2.08TrpLeu: 2.08 ± 0.05	0.386TrpMet: 0.386 ± 0.019	0.416TrpAsn: 0.416 ± 0.019	0.705TrpPro: 0.705 ± 0.023	0.767TrpGln: 0.767 ± 0.026	1.261TrpArg: 1.261 ± 0.034	0.793TrpSer: 0.793 ± 0.028	0.664TrpThr: 0.664 ± 0.023	0.971TrpVal: 0.971 ± 0.03	0.258TrpTrp: 0.258 ± 0.017	0.374TrpTyr: 0.374 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.376TyrAla: 2.376 ± 0.046	0.265TyrCys: 0.265 ± 0.013	1.443TyrAsp: 1.443 ± 0.037	1.286TyrGlu: 1.286 ± 0.033	0.909TyrPhe: 0.909 ± 0.027	2.179TyrGly: 2.179 ± 0.047	0.639TyrHis: 0.639 ± 0.024	0.89TyrIle: 0.89 ± 0.024	0.428TyrLys: 0.428 ± 0.018	2.625TyrLeu: 2.625 ± 0.05	0.494TyrMet: 0.494 ± 0.02	0.604TyrAsn: 0.604 ± 0.022	1.192TyrPro: 1.192 ± 0.035	0.99TyrGln: 0.99 ± 0.027	2.237TyrArg: 2.237 ± 0.049	1.211TyrSer: 1.211 ± 0.032	1.249TyrThr: 1.249 ± 0.033	1.613TyrVal: 1.613 ± 0.04	0.439TyrTrp: 0.439 ± 0.018	0.728TyrTyr: 0.728 ± 0.028	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.001XaaGlu: 0.001 ± 0.001	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.002XaaXaa: 0.002 ± 0.002

Statistics based on 3698 proteins (1223554 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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