Amino acid dipepetide frequency for Solanum nodiflorum mottle virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.36AlaAla: 7.36 ± 1.464
1.472AlaCys: 1.472 ± 0.568
2.453AlaAsp: 2.453 ± 0.619
5.397AlaGlu: 5.397 ± 1.035
1.472AlaPhe: 1.472 ± 1.116
3.435AlaGly: 3.435 ± 2.471
0.981AlaHis: 0.981 ± 0.357
0.981AlaIle: 0.981 ± 0.536
3.435AlaLys: 3.435 ± 1.235
4.907AlaLeu: 4.907 ± 0.946
1.472AlaMet: 1.472 ± 0.618
1.963AlaAsn: 1.963 ± 0.786
4.416AlaPro: 4.416 ± 1.633
0.981AlaGln: 0.981 ± 0.536
1.472AlaArg: 1.472 ± 0.42
9.323AlaSer: 9.323 ± 2.531
5.397AlaThr: 5.397 ± 2.618
5.397AlaVal: 5.397 ± 1.132
1.472AlaTrp: 1.472 ± 0.499
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.981CysAla: 0.981 ± 0.65
0.0CysCys: 0.0 ± 0.0
1.472CysAsp: 1.472 ± 1.334
0.491CysGlu: 0.491 ± 0.31
0.981CysPhe: 0.981 ± 0.62
0.491CysGly: 0.491 ± 0.718
0.491CysHis: 0.491 ± 0.62
1.472CysIle: 1.472 ± 0.568
0.981CysLys: 0.981 ± 0.62
1.963CysLeu: 1.963 ± 0.75
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.491CysPro: 0.491 ± 0.31
1.963CysGln: 1.963 ± 0.714
0.491CysArg: 0.491 ± 0.31
1.963CysSer: 1.963 ± 0.787
1.963CysThr: 1.963 ± 0.323
0.491CysVal: 0.491 ± 0.62
0.0CysTrp: 0.0 ± 0.0
0.491CysTyr: 0.491 ± 0.31
0.0CysXaa: 0.0 ± 0.0
Asp
1.472AspAla: 1.472 ± 2.155
0.981AspCys: 0.981 ± 0.536
4.416AspAsp: 4.416 ± 1.496
3.435AspGlu: 3.435 ± 1.988
2.453AspPhe: 2.453 ± 0.81
2.944AspGly: 2.944 ± 0.998
0.981AspHis: 0.981 ± 0.62
2.453AspIle: 2.453 ± 0.619
1.963AspLys: 1.963 ± 0.323
4.907AspLeu: 4.907 ± 1.03
1.472AspMet: 1.472 ± 0.499
0.981AspAsn: 0.981 ± 1.071
2.944AspPro: 2.944 ± 0.998
0.981AspGln: 0.981 ± 0.65
0.981AspArg: 0.981 ± 0.62
6.379AspSer: 6.379 ± 1.43
0.981AspThr: 0.981 ± 1.071
2.453AspVal: 2.453 ± 0.81
0.981AspTrp: 0.981 ± 0.65
1.472AspTyr: 1.472 ± 0.568
0.0AspXaa: 0.0 ± 0.0
Glu
2.453GluAla: 2.453 ± 1.033
0.491GluCys: 0.491 ± 0.445
0.491GluAsp: 0.491 ± 0.718
3.435GluGlu: 3.435 ± 1.096
5.397GluPhe: 5.397 ± 1.035
4.907GluGly: 4.907 ± 1.925
0.491GluHis: 0.491 ± 0.718
4.907GluIle: 4.907 ± 0.599
2.453GluLys: 2.453 ± 0.474
11.286GluLeu: 11.286 ± 2.867
0.491GluMet: 0.491 ± 0.445
3.925GluAsn: 3.925 ± 1.207
5.888GluPro: 5.888 ± 0.49
0.491GluGln: 0.491 ± 0.31
4.907GluArg: 4.907 ± 1.439
8.342GluSer: 8.342 ± 1.926
4.907GluThr: 4.907 ± 1.193
5.397GluVal: 5.397 ± 1.951
1.472GluTrp: 1.472 ± 0.93
2.944GluTyr: 2.944 ± 0.998
0.0GluXaa: 0.0 ± 0.0
Phe
1.472PheAla: 1.472 ± 0.568
0.981PheCys: 0.981 ± 0.62
1.963PheAsp: 1.963 ± 0.504
1.472PheGlu: 1.472 ± 0.42
0.0PhePhe: 0.0 ± 0.0
5.397PheGly: 5.397 ± 1.133
0.0PheHis: 0.0 ± 0.0
1.963PheIle: 1.963 ± 0.786
0.981PheLys: 0.981 ± 0.357
1.472PheLeu: 1.472 ± 0.93
0.491PheMet: 0.491 ± 0.31
0.981PheAsn: 0.981 ± 0.65
0.0PhePro: 0.0 ± 0.0
2.944PheGln: 2.944 ± 0.421
2.944PheArg: 2.944 ± 1.328
4.907PheSer: 4.907 ± 1.882
0.0PheThr: 0.0 ± 0.0
1.963PheVal: 1.963 ± 0.75
0.491PheTrp: 0.491 ± 0.31
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
5.888GlyAla: 5.888 ± 2.214
0.981GlyCys: 0.981 ± 0.62
4.907GlyAsp: 4.907 ± 1.324
4.907GlyGlu: 4.907 ± 0.742
2.944GlyPhe: 2.944 ± 0.421
2.944GlyGly: 2.944 ± 0.421
1.472GlyHis: 1.472 ± 0.93
3.925GlyIle: 3.925 ± 0.646
3.925GlyLys: 3.925 ± 1.429
6.379GlyLeu: 6.379 ± 1.65
2.453GlyMet: 2.453 ± 0.474
1.963GlyAsn: 1.963 ± 1.724
3.925GlyPro: 3.925 ± 1.429
1.963GlyGln: 1.963 ± 0.68
3.435GlyArg: 3.435 ± 0.639
8.342GlySer: 8.342 ± 1.473
0.491GlyThr: 0.491 ± 0.62
5.888GlyVal: 5.888 ± 2.143
2.944GlyTrp: 2.944 ± 0.998
0.491GlyTyr: 0.491 ± 0.62
0.0GlyXaa: 0.0 ± 0.0
His
0.491HisAla: 0.491 ± 0.31
0.491HisCys: 0.491 ± 0.31
0.0HisAsp: 0.0 ± 0.0
0.981HisGlu: 0.981 ± 0.62
0.0HisPhe: 0.0 ± 0.0
1.472HisGly: 1.472 ± 0.499
1.472HisHis: 1.472 ± 0.568
0.981HisIle: 0.981 ± 1.071
1.472HisLys: 1.472 ± 0.499
1.472HisLeu: 1.472 ± 0.568
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.491HisPro: 0.491 ± 0.31
0.0HisGln: 0.0 ± 0.0
1.963HisArg: 1.963 ± 0.9
2.453HisSer: 2.453 ± 0.474
2.453HisThr: 2.453 ± 0.81
1.963HisVal: 1.963 ± 0.75
0.0HisTrp: 0.0 ± 0.0
0.491HisTyr: 0.491 ± 0.31
0.0HisXaa: 0.0 ± 0.0
Ile
4.907IleAla: 4.907 ± 0.946
0.0IleCys: 0.0 ± 0.0
2.944IleAsp: 2.944 ± 1.454
1.472IleGlu: 1.472 ± 0.618
0.0IlePhe: 0.0 ± 0.0
2.944IleGly: 2.944 ± 0.998
0.981IleHis: 0.981 ± 0.357
1.472IleIle: 1.472 ± 1.334
2.453IleLys: 2.453 ± 0.81
4.416IleLeu: 4.416 ± 1.36
0.491IleMet: 0.491 ± 0.31
0.981IleAsn: 0.981 ± 0.62
4.416IlePro: 4.416 ± 1.132
1.472IleGln: 1.472 ± 0.42
2.453IleArg: 2.453 ± 0.81
4.416IleSer: 4.416 ± 1.802
2.944IleThr: 2.944 ± 0.586
4.416IleVal: 4.416 ± 0.636
0.0IleTrp: 0.0 ± 0.0
1.963IleTyr: 1.963 ± 0.714
0.0IleXaa: 0.0 ± 0.0
Lys
3.435LysAla: 3.435 ± 0.682
0.981LysCys: 0.981 ± 0.357
0.491LysAsp: 0.491 ± 0.31
7.851LysGlu: 7.851 ± 2.09
2.453LysPhe: 2.453 ± 0.614
6.869LysGly: 6.869 ± 1.738
1.963LysHis: 1.963 ± 1.239
0.981LysIle: 0.981 ± 0.357
2.453LysLys: 2.453 ± 0.619
5.397LysLeu: 5.397 ± 0.517
0.981LysMet: 0.981 ± 0.357
1.472LysAsn: 1.472 ± 0.568
5.888LysPro: 5.888 ± 1.762
1.963LysGln: 1.963 ± 1.239
2.453LysArg: 2.453 ± 0.853
2.453LysSer: 2.453 ± 0.473
1.963LysThr: 1.963 ± 0.75
2.944LysVal: 2.944 ± 0.998
0.981LysTrp: 0.981 ± 1.239
1.472LysTyr: 1.472 ± 0.499
0.0LysXaa: 0.0 ± 0.0
Leu
3.925LeuAla: 3.925 ± 0.801
2.453LeuCys: 2.453 ± 0.474
6.869LeuAsp: 6.869 ± 0.961
7.36LeuGlu: 7.36 ± 1.594
2.944LeuPhe: 2.944 ± 1.073
3.435LeuGly: 3.435 ± 0.328
2.453LeuHis: 2.453 ± 0.619
6.869LeuIle: 6.869 ± 0.241
8.342LeuLys: 8.342 ± 1.107
10.795LeuLeu: 10.795 ± 1.709
1.963LeuMet: 1.963 ± 0.818
2.944LeuAsn: 2.944 ± 0.832
8.342LeuPro: 8.342 ± 2.062
0.981LeuGln: 0.981 ± 0.357
4.416LeuArg: 4.416 ± 2.015
7.851LeuSer: 7.851 ± 1.055
6.379LeuThr: 6.379 ± 0.881
7.851LeuVal: 7.851 ± 2.414
0.981LeuTrp: 0.981 ± 0.62
4.416LeuTyr: 4.416 ± 0.636
0.0LeuXaa: 0.0 ± 0.0
Met
2.453MetAla: 2.453 ± 0.473
0.0MetCys: 0.0 ± 0.0
0.491MetAsp: 0.491 ± 0.445
1.472MetGlu: 1.472 ± 0.42
0.491MetPhe: 0.491 ± 0.31
3.435MetGly: 3.435 ± 1.02
0.491MetHis: 0.491 ± 0.31
2.453MetIle: 2.453 ± 0.81
0.491MetLys: 0.491 ± 0.31
1.963MetLeu: 1.963 ± 0.75
0.0MetMet: 0.0 ± 0.0
0.491MetAsn: 0.491 ± 0.62
0.981MetPro: 0.981 ± 1.071
0.0MetGln: 0.0 ± 0.0
0.491MetArg: 0.491 ± 0.31
1.963MetSer: 1.963 ± 0.68
0.0MetThr: 0.0 ± 0.0
1.963MetVal: 1.963 ± 1.724
1.472MetTrp: 1.472 ± 0.499
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.963AsnAla: 1.963 ± 0.996
0.981AsnCys: 0.981 ± 0.763
0.981AsnAsp: 0.981 ± 0.62
2.944AsnGlu: 2.944 ± 0.733
1.963AsnPhe: 1.963 ± 0.323
2.944AsnGly: 2.944 ± 0.535
0.0AsnHis: 0.0 ± 0.0
0.0AsnIle: 0.0 ± 0.0
2.453AsnLys: 2.453 ± 0.81
4.416AsnLeu: 4.416 ± 1.607
0.981AsnMet: 0.981 ± 0.473
0.491AsnAsn: 0.491 ± 0.62
1.963AsnPro: 1.963 ± 2.17
0.981AsnGln: 0.981 ± 0.357
0.981AsnArg: 0.981 ± 0.62
2.944AsnSer: 2.944 ± 0.998
1.963AsnThr: 1.963 ± 2.17
0.981AsnVal: 0.981 ± 0.763
0.981AsnTrp: 0.981 ± 0.357
1.963AsnTyr: 1.963 ± 0.714
0.0AsnXaa: 0.0 ± 0.0
Pro
6.869ProAla: 6.869 ± 1.508
0.981ProCys: 0.981 ± 0.65
3.925ProAsp: 3.925 ± 0.826
3.925ProGlu: 3.925 ± 0.812
0.491ProPhe: 0.491 ± 0.718
4.416ProGly: 4.416 ± 0.914
2.453ProHis: 2.453 ± 0.81
3.435ProIle: 3.435 ± 2.189
2.453ProLys: 2.453 ± 0.81
6.379ProLeu: 6.379 ± 1.459
1.472ProMet: 1.472 ± 0.571
3.435ProAsn: 3.435 ± 0.726
1.472ProPro: 1.472 ± 1.859
0.491ProGln: 0.491 ± 0.31
2.453ProArg: 2.453 ± 1.114
7.36ProSer: 7.36 ± 1.418
2.944ProThr: 2.944 ± 0.809
2.453ProVal: 2.453 ± 1.07
1.472ProTrp: 1.472 ± 0.618
2.453ProTyr: 2.453 ± 0.81
0.0ProXaa: 0.0 ± 0.0
Gln
1.963GlnAla: 1.963 ± 0.75
0.491GlnCys: 0.491 ± 0.31
0.0GlnAsp: 0.0 ± 0.0
2.453GlnGlu: 2.453 ± 1.033
0.981GlnPhe: 0.981 ± 0.357
0.0GlnGly: 0.0 ± 0.0
0.0GlnHis: 0.0 ± 0.0
2.453GlnIle: 2.453 ± 0.81
0.981GlnLys: 0.981 ± 0.891
4.416GlnLeu: 4.416 ± 1.464
0.981GlnMet: 0.981 ± 0.357
0.981GlnAsn: 0.981 ± 0.357
2.453GlnPro: 2.453 ± 1.081
0.0GlnGln: 0.0 ± 0.0
2.944GlnArg: 2.944 ± 1.491
0.491GlnSer: 0.491 ± 0.62
1.472GlnThr: 1.472 ± 0.618
0.491GlnVal: 0.491 ± 0.31
0.0GlnTrp: 0.0 ± 0.0
1.472GlnTyr: 1.472 ± 1.859
0.0GlnXaa: 0.0 ± 0.0
Arg
2.944ArgAla: 2.944 ± 0.421
0.981ArgCys: 0.981 ± 0.62
2.453ArgAsp: 2.453 ± 0.614
5.888ArgGlu: 5.888 ± 0.894
1.963ArgPhe: 1.963 ± 0.9
3.925ArgGly: 3.925 ± 0.251
0.981ArgHis: 0.981 ± 0.65
0.981ArgIle: 0.981 ± 0.62
2.944ArgLys: 2.944 ± 0.809
5.397ArgLeu: 5.397 ± 1.133
1.472ArgMet: 1.472 ± 0.499
1.472ArgAsn: 1.472 ± 1.116
2.944ArgPro: 2.944 ± 1.107
1.963ArgGln: 1.963 ± 0.68
5.888ArgArg: 5.888 ± 4.011
4.907ArgSer: 4.907 ± 1.436
0.0ArgThr: 0.0 ± 0.0
5.888ArgVal: 5.888 ± 0.795
0.981ArgTrp: 0.981 ± 0.536
2.453ArgTyr: 2.453 ± 0.474
0.0ArgXaa: 0.0 ± 0.0
Ser
2.944SerAla: 2.944 ± 0.535
0.491SerCys: 0.491 ± 0.445
4.907SerAsp: 4.907 ± 1.03
5.888SerGlu: 5.888 ± 1.538
2.453SerPhe: 2.453 ± 0.81
6.869SerGly: 6.869 ± 0.951
0.981SerHis: 0.981 ± 0.62
2.453SerIle: 2.453 ± 1.136
8.342SerLys: 8.342 ± 1.634
12.758SerLeu: 12.758 ± 2.228
1.472SerMet: 1.472 ± 0.687
2.944SerAsn: 2.944 ± 0.86
4.907SerPro: 4.907 ± 2.545
3.925SerGln: 3.925 ± 1.429
9.814SerArg: 9.814 ± 2.361
12.758SerSer: 12.758 ± 4.847
9.323SerThr: 9.323 ± 3.171
7.851SerVal: 7.851 ± 1.084
0.981SerTrp: 0.981 ± 0.536
2.944SerTyr: 2.944 ± 1.833
0.0SerXaa: 0.0 ± 0.0
Thr
6.379ThrAla: 6.379 ± 1.836
1.963ThrCys: 1.963 ± 0.504
2.453ThrAsp: 2.453 ± 1.979
3.925ThrGlu: 3.925 ± 1.954
1.963ThrPhe: 1.963 ± 0.323
2.453ThrGly: 2.453 ± 0.81
0.491ThrHis: 0.491 ± 0.31
2.453ThrIle: 2.453 ± 0.614
1.472ThrLys: 1.472 ± 0.568
5.397ThrLeu: 5.397 ± 0.84
1.963ThrMet: 1.963 ± 0.996
1.963ThrAsn: 1.963 ± 0.874
2.944ThrPro: 2.944 ± 1.295
1.472ThrGln: 1.472 ± 0.42
1.963ThrArg: 1.963 ± 0.504
5.888ThrSer: 5.888 ± 1.172
3.925ThrThr: 3.925 ± 1.993
3.925ThrVal: 3.925 ± 1.572
0.491ThrTrp: 0.491 ± 0.31
0.981ThrTyr: 0.981 ± 1.071
0.0ThrXaa: 0.0 ± 0.0
Val
2.453ValAla: 2.453 ± 0.474
1.963ValCys: 1.963 ± 1.57
3.435ValAsp: 3.435 ± 0.699
9.814ValGlu: 9.814 ± 2.421
1.472ValPhe: 1.472 ± 0.93
7.36ValGly: 7.36 ± 1.207
1.472ValHis: 1.472 ± 0.42
2.944ValIle: 2.944 ± 1.072
3.435ValLys: 3.435 ± 0.568
2.944ValLeu: 2.944 ± 0.84
1.472ValMet: 1.472 ± 1.859
2.944ValAsn: 2.944 ± 1.107
3.435ValPro: 3.435 ± 0.682
1.963ValGln: 1.963 ± 0.323
2.944ValArg: 2.944 ± 0.998
6.379ValSer: 6.379 ± 2.169
4.416ValThr: 4.416 ± 1.829
3.925ValVal: 3.925 ± 1.234
0.981ValTrp: 0.981 ± 0.357
4.416ValTyr: 4.416 ± 1.075
0.0ValXaa: 0.0 ± 0.0
Trp
3.435TrpAla: 3.435 ± 0.568
0.0TrpCys: 0.0 ± 0.0
0.491TrpAsp: 0.491 ± 0.31
0.491TrpGlu: 0.491 ± 0.31
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.981TrpIle: 0.981 ± 0.536
1.472TrpLys: 1.472 ± 0.568
0.981TrpLeu: 0.981 ± 0.536
0.981TrpMet: 0.981 ± 0.357
0.491TrpAsn: 0.491 ± 0.31
1.963TrpPro: 1.963 ± 0.75
0.0TrpGln: 0.0 ± 0.0
0.981TrpArg: 0.981 ± 1.071
3.925TrpSer: 3.925 ± 1.499
0.491TrpThr: 0.491 ± 0.31
0.491TrpVal: 0.491 ± 0.31
0.981TrpTrp: 0.981 ± 0.357
0.981TrpTyr: 0.981 ± 0.536
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
0.491TyrCys: 0.491 ± 0.31
0.491TyrAsp: 0.491 ± 0.62
1.472TyrGlu: 1.472 ± 0.42
0.0TyrPhe: 0.0 ± 0.0
3.925TyrGly: 3.925 ± 0.945
0.491TyrHis: 0.491 ± 0.31
0.981TyrIle: 0.981 ± 0.357
2.944TyrLys: 2.944 ± 0.421
3.925TyrLeu: 3.925 ± 1.298
0.0TyrMet: 0.0 ± 0.0
2.944TyrAsn: 2.944 ± 1.072
1.472TyrPro: 1.472 ± 0.499
0.491TyrGln: 0.491 ± 0.62
2.453TyrArg: 2.453 ± 1.476
1.963TyrSer: 1.963 ± 0.714
2.453TyrThr: 2.453 ± 1.951
3.435TyrVal: 3.435 ± 1.692
1.472TyrTrp: 1.472 ± 0.568
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (2039 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski