Amino acid dipepetide frequency for Lysinibacillus contaminans

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.11AlaAla: 6.11 ± 0.085
0.643AlaCys: 0.643 ± 0.022
3.669AlaAsp: 3.669 ± 0.065
4.925AlaGlu: 4.925 ± 0.088
3.544AlaPhe: 3.544 ± 0.063
5.204AlaGly: 5.204 ± 0.081
1.439AlaHis: 1.439 ± 0.045
6.862AlaIle: 6.862 ± 0.092
4.982AlaLys: 4.982 ± 0.087
8.015AlaLeu: 8.015 ± 0.104
2.297AlaMet: 2.297 ± 0.049
3.027AlaAsn: 3.027 ± 0.054
2.14AlaPro: 2.14 ± 0.051
2.796AlaGln: 2.796 ± 0.054
2.677AlaArg: 2.677 ± 0.053
4.374AlaSer: 4.374 ± 0.076
4.406AlaThr: 4.406 ± 0.067
5.706AlaVal: 5.706 ± 0.076
0.644AlaTrp: 0.644 ± 0.025
2.572AlaTyr: 2.572 ± 0.048
0.0AlaXaa: 0.0 ± 0.0
Cys
0.468CysAla: 0.468 ± 0.02
0.106CysCys: 0.106 ± 0.012
0.366CysAsp: 0.366 ± 0.02
0.472CysGlu: 0.472 ± 0.024
0.322CysPhe: 0.322 ± 0.017
0.664CysGly: 0.664 ± 0.026
0.169CysHis: 0.169 ± 0.011
0.641CysIle: 0.641 ± 0.025
0.37CysLys: 0.37 ± 0.021
0.644CysLeu: 0.644 ± 0.025
0.192CysMet: 0.192 ± 0.013
0.29CysAsn: 0.29 ± 0.015
0.3CysPro: 0.3 ± 0.016
0.21CysGln: 0.21 ± 0.014
0.267CysArg: 0.267 ± 0.015
0.468CysSer: 0.468 ± 0.022
0.399CysThr: 0.399 ± 0.019
0.467CysVal: 0.467 ± 0.022
0.066CysTrp: 0.066 ± 0.008
0.265CysTyr: 0.265 ± 0.016
0.0CysXaa: 0.0 ± 0.0
Asp
3.827AspAla: 3.827 ± 0.063
0.373AspCys: 0.373 ± 0.021
2.404AspAsp: 2.404 ± 0.052
4.482AspGlu: 4.482 ± 0.062
2.573AspPhe: 2.573 ± 0.045
3.325AspGly: 3.325 ± 0.066
0.953AspHis: 0.953 ± 0.032
4.246AspIle: 4.246 ± 0.056
2.896AspLys: 2.896 ± 0.053
4.782AspLeu: 4.782 ± 0.065
1.343AspMet: 1.343 ± 0.04
1.82AspAsn: 1.82 ± 0.045
1.66AspPro: 1.66 ± 0.045
1.555AspGln: 1.555 ± 0.038
1.883AspArg: 1.883 ± 0.043
2.433AspSer: 2.433 ± 0.049
2.591AspThr: 2.591 ± 0.051
3.977AspVal: 3.977 ± 0.06
0.559AspTrp: 0.559 ± 0.024
2.082AspTyr: 2.082 ± 0.045
0.0AspXaa: 0.0 ± 0.0
Glu
5.698GluAla: 5.698 ± 0.092
0.365GluCys: 0.365 ± 0.019
3.68GluAsp: 3.68 ± 0.066
6.559GluGlu: 6.559 ± 0.1
2.46GluPhe: 2.46 ± 0.048
4.02GluGly: 4.02 ± 0.059
1.509GluHis: 1.509 ± 0.041
5.522GluIle: 5.522 ± 0.086
6.089GluLys: 6.089 ± 0.081
7.004GluLeu: 7.004 ± 0.09
2.266GluMet: 2.266 ± 0.044
3.662GluAsn: 3.662 ± 0.057
1.906GluPro: 1.906 ± 0.046
3.885GluGln: 3.885 ± 0.078
3.324GluArg: 3.324 ± 0.064
3.404GluSer: 3.404 ± 0.055
3.782GluThr: 3.782 ± 0.069
5.16GluVal: 5.16 ± 0.085
0.774GluTrp: 0.774 ± 0.025
2.085GluTyr: 2.085 ± 0.042
0.0GluXaa: 0.0 ± 0.0
Phe
3.396PheAla: 3.396 ± 0.06
0.353PheCys: 0.353 ± 0.021
2.532PheAsp: 2.532 ± 0.056
3.078PheGlu: 3.078 ± 0.058
2.355PhePhe: 2.355 ± 0.063
3.355PheGly: 3.355 ± 0.065
0.88PheHis: 0.88 ± 0.032
4.091PheIle: 4.091 ± 0.082
2.438PheLys: 2.438 ± 0.048
4.41PheLeu: 4.41 ± 0.08
1.277PheMet: 1.277 ± 0.035
2.012PheAsn: 2.012 ± 0.043
1.508PhePro: 1.508 ± 0.039
1.48PheGln: 1.48 ± 0.039
1.379PheArg: 1.379 ± 0.033
3.235PheSer: 3.235 ± 0.055
2.909PheThr: 2.909 ± 0.059
3.493PheVal: 3.493 ± 0.064
0.438PheTrp: 0.438 ± 0.026
1.745PheTyr: 1.745 ± 0.039
0.0PheXaa: 0.0 ± 0.0
Gly
5.012GlyAla: 5.012 ± 0.085
0.595GlyCys: 0.595 ± 0.026
3.196GlyAsp: 3.196 ± 0.055
4.42GlyGlu: 4.42 ± 0.068
3.39GlyPhe: 3.39 ± 0.053
4.5GlyGly: 4.5 ± 0.086
1.314GlyHis: 1.314 ± 0.039
5.838GlyIle: 5.838 ± 0.085
4.477GlyLys: 4.477 ± 0.066
6.294GlyLeu: 6.294 ± 0.092
2.065GlyMet: 2.065 ± 0.05
2.555GlyAsn: 2.555 ± 0.06
1.6GlyPro: 1.6 ± 0.042
2.312GlyGln: 2.312 ± 0.051
2.43GlyArg: 2.43 ± 0.055
3.702GlySer: 3.702 ± 0.065
3.977GlyThr: 3.977 ± 0.067
5.132GlyVal: 5.132 ± 0.082
0.716GlyTrp: 0.716 ± 0.026
2.716GlyTyr: 2.716 ± 0.05
0.0GlyXaa: 0.0 ± 0.0
His
1.473HisAla: 1.473 ± 0.041
0.203HisCys: 0.203 ± 0.015
0.92HisAsp: 0.92 ± 0.032
1.366HisGlu: 1.366 ± 0.039
1.06HisPhe: 1.06 ± 0.034
1.316HisGly: 1.316 ± 0.037
0.595HisHis: 0.595 ± 0.026
1.517HisIle: 1.517 ± 0.037
1.013HisLys: 1.013 ± 0.031
2.048HisLeu: 2.048 ± 0.048
0.539HisMet: 0.539 ± 0.022
0.806HisAsn: 0.806 ± 0.027
0.975HisPro: 0.975 ± 0.033
0.774HisGln: 0.774 ± 0.028
0.801HisArg: 0.801 ± 0.029
1.133HisSer: 1.133 ± 0.032
1.111HisThr: 1.111 ± 0.04
1.429HisVal: 1.429 ± 0.042
0.212HisTrp: 0.212 ± 0.014
0.85HisTyr: 0.85 ± 0.031
0.0HisXaa: 0.0 ± 0.0
Ile
6.815IleAla: 6.815 ± 0.082
0.651IleCys: 0.651 ± 0.025
4.316IleAsp: 4.316 ± 0.074
6.134IleGlu: 6.134 ± 0.085
3.567IlePhe: 3.567 ± 0.07
6.126IleGly: 6.126 ± 0.088
1.651IleHis: 1.651 ± 0.041
6.069IleIle: 6.069 ± 0.095
3.933IleLys: 3.933 ± 0.066
7.489IleLeu: 7.489 ± 0.095
1.994IleMet: 1.994 ± 0.043
3.169IleAsn: 3.169 ± 0.059
3.083IlePro: 3.083 ± 0.06
3.058IleGln: 3.058 ± 0.059
3.027IleArg: 3.027 ± 0.06
5.034IleSer: 5.034 ± 0.07
4.603IleThr: 4.603 ± 0.071
6.282IleVal: 6.282 ± 0.092
0.671IleTrp: 0.671 ± 0.027
2.527IleTyr: 2.527 ± 0.05
0.0IleXaa: 0.0 ± 0.0
Lys
4.516LysAla: 4.516 ± 0.077
0.332LysCys: 0.332 ± 0.02
3.443LysAsp: 3.443 ± 0.069
5.957LysGlu: 5.957 ± 0.093
2.057LysPhe: 2.057 ± 0.045
3.944LysGly: 3.944 ± 0.057
1.277LysHis: 1.277 ± 0.033
4.756LysIle: 4.756 ± 0.069
5.228LysLys: 5.228 ± 0.079
5.789LysLeu: 5.789 ± 0.076
2.215LysMet: 2.215 ± 0.041
3.28LysAsn: 3.28 ± 0.06
2.082LysPro: 2.082 ± 0.053
2.842LysGln: 2.842 ± 0.059
2.775LysArg: 2.775 ± 0.05
3.349LysSer: 3.349 ± 0.067
3.497LysThr: 3.497 ± 0.057
4.474LysVal: 4.474 ± 0.073
0.861LysTrp: 0.861 ± 0.031
2.274LysTyr: 2.274 ± 0.049
0.0LysXaa: 0.0 ± 0.0
Leu
8.052LeuAla: 8.052 ± 0.096
0.689LeuCys: 0.689 ± 0.027
4.677LeuAsp: 4.677 ± 0.066
6.431LeuGlu: 6.431 ± 0.092
4.931LeuPhe: 4.931 ± 0.097
6.307LeuGly: 6.307 ± 0.102
2.008LeuHis: 2.008 ± 0.051
7.072LeuIle: 7.072 ± 0.102
6.11LeuLys: 6.11 ± 0.072
10.466LeuLeu: 10.466 ± 0.153
2.681LeuMet: 2.681 ± 0.05
4.23LeuAsn: 4.23 ± 0.075
3.849LeuPro: 3.849 ± 0.051
4.325LeuGln: 4.325 ± 0.073
3.567LeuArg: 3.567 ± 0.069
6.445LeuSer: 6.445 ± 0.076
6.081LeuThr: 6.081 ± 0.071
6.784LeuVal: 6.784 ± 0.102
0.76LeuTrp: 0.76 ± 0.029
3.181LeuTyr: 3.181 ± 0.065
0.0LeuXaa: 0.0 ± 0.0
Met
2.132MetAla: 2.132 ± 0.043
0.152MetCys: 0.152 ± 0.012
1.472MetAsp: 1.472 ± 0.039
1.877MetGlu: 1.877 ± 0.046
1.107MetPhe: 1.107 ± 0.032
1.736MetGly: 1.736 ± 0.045
0.552MetHis: 0.552 ± 0.026
2.16MetIle: 2.16 ± 0.044
2.445MetLys: 2.445 ± 0.053
2.797MetLeu: 2.797 ± 0.059
0.989MetMet: 0.989 ± 0.032
1.523MetAsn: 1.523 ± 0.042
1.119MetPro: 1.119 ± 0.04
1.266MetGln: 1.266 ± 0.036
1.196MetArg: 1.196 ± 0.032
1.708MetSer: 1.708 ± 0.039
1.927MetThr: 1.927 ± 0.05
1.667MetVal: 1.667 ± 0.042
0.214MetTrp: 0.214 ± 0.014
0.83MetTyr: 0.83 ± 0.032
0.0MetXaa: 0.0 ± 0.0
Asn
3.178AsnAla: 3.178 ± 0.063
0.33AsnCys: 0.33 ± 0.019
2.192AsnAsp: 2.192 ± 0.047
3.439AsnGlu: 3.439 ± 0.067
1.842AsnPhe: 1.842 ± 0.044
3.261AsnGly: 3.261 ± 0.06
0.906AsnHis: 0.906 ± 0.029
3.505AsnIle: 3.505 ± 0.06
2.73AsnLys: 2.73 ± 0.061
3.821AsnLeu: 3.821 ± 0.062
1.184AsnMet: 1.184 ± 0.032
1.995AsnAsn: 1.995 ± 0.051
2.028AsnPro: 2.028 ± 0.082
1.527AsnGln: 1.527 ± 0.031
1.829AsnArg: 1.829 ± 0.042
2.32AsnSer: 2.32 ± 0.052
2.339AsnThr: 2.339 ± 0.055
3.199AsnVal: 3.199 ± 0.058
0.467AsnTrp: 0.467 ± 0.019
1.58AsnTyr: 1.58 ± 0.038
0.0AsnXaa: 0.0 ± 0.0
Pro
2.241ProAla: 2.241 ± 0.052
0.189ProCys: 0.189 ± 0.013
1.717ProAsp: 1.717 ± 0.044
2.595ProGlu: 2.595 ± 0.06
1.912ProPhe: 1.912 ± 0.04
2.01ProGly: 2.01 ± 0.049
0.738ProHis: 0.738 ± 0.025
2.886ProIle: 2.886 ± 0.051
2.078ProLys: 2.078 ± 0.048
3.362ProLeu: 3.362 ± 0.062
0.888ProMet: 0.888 ± 0.034
1.634ProAsn: 1.634 ± 0.041
0.907ProPro: 0.907 ± 0.042
1.141ProGln: 1.141 ± 0.034
0.905ProArg: 0.905 ± 0.028
2.158ProSer: 2.158 ± 0.042
2.175ProThr: 2.175 ± 0.047
2.681ProVal: 2.681 ± 0.061
0.314ProTrp: 0.314 ± 0.019
1.31ProTyr: 1.31 ± 0.036
0.0ProXaa: 0.0 ± 0.0
Gln
3.026GlnAla: 3.026 ± 0.06
0.206GlnCys: 0.206 ± 0.015
1.716GlnAsp: 1.716 ± 0.037
2.885GlnGlu: 2.885 ± 0.066
1.736GlnPhe: 1.736 ± 0.042
2.105GlnGly: 2.105 ± 0.044
0.851GlnHis: 0.851 ± 0.029
2.803GlnIle: 2.803 ± 0.058
2.63GlnLys: 2.63 ± 0.052
4.376GlnLeu: 4.376 ± 0.074
1.201GlnMet: 1.201 ± 0.037
1.728GlnAsn: 1.728 ± 0.044
1.166GlnPro: 1.166 ± 0.03
2.231GlnGln: 2.231 ± 0.052
1.497GlnArg: 1.497 ± 0.04
2.232GlnSer: 2.232 ± 0.05
2.181GlnThr: 2.181 ± 0.046
2.589GlnVal: 2.589 ± 0.057
0.416GlnTrp: 0.416 ± 0.019
1.473GlnTyr: 1.473 ± 0.037
0.0GlnXaa: 0.0 ± 0.0
Arg
2.665ArgAla: 2.665 ± 0.047
0.233ArgCys: 0.233 ± 0.017
1.98ArgAsp: 1.98 ± 0.044
2.891ArgGlu: 2.891 ± 0.06
1.843ArgPhe: 1.843 ± 0.046
2.221ArgGly: 2.221 ± 0.049
0.754ArgHis: 0.754 ± 0.03
2.886ArgIle: 2.886 ± 0.053
2.778ArgLys: 2.778 ± 0.052
3.782ArgLeu: 3.782 ± 0.081
1.187ArgMet: 1.187 ± 0.031
1.67ArgAsn: 1.67 ± 0.039
1.153ArgPro: 1.153 ± 0.034
1.545ArgGln: 1.545 ± 0.04
1.536ArgArg: 1.536 ± 0.049
1.938ArgSer: 1.938 ± 0.047
2.06ArgThr: 2.06 ± 0.043
2.649ArgVal: 2.649 ± 0.055
0.33ArgTrp: 0.33 ± 0.02
1.376ArgTyr: 1.376 ± 0.037
0.0ArgXaa: 0.0 ± 0.0
Ser
3.968SerAla: 3.968 ± 0.063
0.391SerCys: 0.391 ± 0.022
2.66SerAsp: 2.66 ± 0.052
3.721SerGlu: 3.721 ± 0.065
3.19SerPhe: 3.19 ± 0.063
4.119SerGly: 4.119 ± 0.056
1.101SerHis: 1.101 ± 0.034
5.315SerIle: 5.315 ± 0.072
3.73SerLys: 3.73 ± 0.063
5.862SerLeu: 5.862 ± 0.077
1.765SerMet: 1.765 ± 0.04
2.589SerAsn: 2.589 ± 0.06
1.929SerPro: 1.929 ± 0.037
1.864SerGln: 1.864 ± 0.043
1.987SerArg: 1.987 ± 0.049
3.807SerSer: 3.807 ± 0.073
3.488SerThr: 3.488 ± 0.064
4.156SerVal: 4.156 ± 0.058
0.585SerTrp: 0.585 ± 0.027
2.248SerTyr: 2.248 ± 0.046
0.0SerXaa: 0.0 ± 0.0
Thr
4.567ThrAla: 4.567 ± 0.068
0.365ThrCys: 0.365 ± 0.02
2.765ThrAsp: 2.765 ± 0.053
3.659ThrGlu: 3.659 ± 0.061
2.816ThrPhe: 2.816 ± 0.059
4.082ThrGly: 4.082 ± 0.067
1.133ThrHis: 1.133 ± 0.031
4.999ThrIle: 4.999 ± 0.07
3.593ThrLys: 3.593 ± 0.053
5.662ThrLeu: 5.662 ± 0.078
1.54ThrMet: 1.54 ± 0.041
2.712ThrAsn: 2.712 ± 0.057
2.267ThrPro: 2.267 ± 0.051
1.79ThrGln: 1.79 ± 0.043
1.821ThrArg: 1.821 ± 0.046
3.532ThrSer: 3.532 ± 0.066
3.457ThrThr: 3.457 ± 0.065
4.542ThrVal: 4.542 ± 0.067
0.515ThrTrp: 0.515 ± 0.023
2.139ThrTyr: 2.139 ± 0.039
0.0ThrXaa: 0.0 ± 0.0
Val
5.837ValAla: 5.837 ± 0.088
0.585ValCys: 0.585 ± 0.023
3.636ValAsp: 3.636 ± 0.057
5.153ValGlu: 5.153 ± 0.084
3.305ValPhe: 3.305 ± 0.057
4.904ValGly: 4.904 ± 0.087
1.374ValHis: 1.374 ± 0.038
5.64ValIle: 5.64 ± 0.081
4.679ValLys: 4.679 ± 0.074
7.349ValLeu: 7.349 ± 0.087
1.997ValMet: 1.997 ± 0.049
3.032ValAsn: 3.032 ± 0.056
2.669ValPro: 2.669 ± 0.057
2.734ValGln: 2.734 ± 0.055
2.727ValArg: 2.727 ± 0.053
4.535ValSer: 4.535 ± 0.068
4.477ValThr: 4.477 ± 0.07
5.559ValVal: 5.559 ± 0.085
0.576ValTrp: 0.576 ± 0.026
2.307ValTyr: 2.307 ± 0.049
0.0ValXaa: 0.0 ± 0.0
Trp
0.607TrpAla: 0.607 ± 0.023
0.069TrpCys: 0.069 ± 0.008
0.46TrpAsp: 0.46 ± 0.022
0.535TrpGlu: 0.535 ± 0.025
0.482TrpPhe: 0.482 ± 0.023
0.621TrpGly: 0.621 ± 0.024
0.224TrpHis: 0.224 ± 0.015
0.782TrpIle: 0.782 ± 0.031
0.596TrpLys: 0.596 ± 0.022
1.167TrpLeu: 1.167 ± 0.036
0.333TrpMet: 0.333 ± 0.018
0.397TrpAsn: 0.397 ± 0.019
0.248TrpPro: 0.248 ± 0.015
0.478TrpGln: 0.478 ± 0.022
0.396TrpArg: 0.396 ± 0.02
0.582TrpSer: 0.582 ± 0.023
0.535TrpThr: 0.535 ± 0.021
0.648TrpVal: 0.648 ± 0.026
0.124TrpTrp: 0.124 ± 0.01
0.313TrpTyr: 0.313 ± 0.02
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.445TyrAla: 2.445 ± 0.05
0.316TyrCys: 0.316 ± 0.018
1.963TyrAsp: 1.963 ± 0.052
2.575TyrGlu: 2.575 ± 0.047
1.868TyrPhe: 1.868 ± 0.039
2.421TyrGly: 2.421 ± 0.049
0.714TyrHis: 0.714 ± 0.024
2.607TyrIle: 2.607 ± 0.05
2.151TyrLys: 2.151 ± 0.042
3.53TyrLeu: 3.53 ± 0.061
0.916TyrMet: 0.916 ± 0.027
1.54TyrAsn: 1.54 ± 0.039
1.253TyrPro: 1.253 ± 0.036
1.237TyrGln: 1.237 ± 0.033
1.452TyrArg: 1.452 ± 0.042
2.087TyrSer: 2.087 ± 0.049
1.963TyrThr: 1.963 ± 0.047
2.479TyrVal: 2.479 ± 0.044
0.356TyrTrp: 0.356 ± 0.019
1.493TyrTyr: 1.493 ± 0.042
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3656 proteins (1067738 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski