Amino acid dipepetide frequency for Bogoriella caseilytica

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	20.292AlaAla: 20.292 ± 0.236	0.765AlaCys: 0.765 ± 0.03	7.346AlaAsp: 7.346 ± 0.104	10.391AlaGlu: 10.391 ± 0.124	3.411AlaPhe: 3.411 ± 0.065	13.483AlaGly: 13.483 ± 0.147	2.742AlaHis: 2.742 ± 0.056	4.937AlaIle: 4.937 ± 0.077	1.975AlaLys: 1.975 ± 0.053	14.557AlaLeu: 14.557 ± 0.178	2.884AlaMet: 2.884 ± 0.05	1.908AlaAsn: 1.908 ± 0.045	6.724AlaPro: 6.724 ± 0.1	4.379AlaGln: 4.379 ± 0.077	9.412AlaArg: 9.412 ± 0.133	6.636AlaSer: 6.636 ± 0.086	7.369AlaThr: 7.369 ± 0.095	11.82AlaVal: 11.82 ± 0.144	1.946AlaTrp: 1.946 ± 0.049	2.236AlaTyr: 2.236 ± 0.053	0.0AlaXaa: 0.0 ± 0.0
Cys	0.718CysAla: 0.718 ± 0.032	0.052CysCys: 0.052 ± 0.007	0.319CysAsp: 0.319 ± 0.019	0.32CysGlu: 0.32 ± 0.019	0.165CysPhe: 0.165 ± 0.013	0.652CysGly: 0.652 ± 0.026	0.138CysHis: 0.138 ± 0.011	0.149CysIle: 0.149 ± 0.011	0.044CysLys: 0.044 ± 0.006	0.53CysLeu: 0.53 ± 0.024	0.078CysMet: 0.078 ± 0.009	0.103CysAsn: 0.103 ± 0.011	0.331CysPro: 0.331 ± 0.022	0.159CysGln: 0.159 ± 0.012	0.346CysArg: 0.346 ± 0.021	0.321CysSer: 0.321 ± 0.018	0.362CysThr: 0.362 ± 0.021	0.413CysVal: 0.413 ± 0.022	0.091CysTrp: 0.091 ± 0.013	0.102CysTyr: 0.102 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	7.169AspAla: 7.169 ± 0.105	0.271AspCys: 0.271 ± 0.017	3.629AspAsp: 3.629 ± 0.083	4.267AspGlu: 4.267 ± 0.084	1.684AspPhe: 1.684 ± 0.047	5.972AspGly: 5.972 ± 0.095	1.393AspHis: 1.393 ± 0.04	1.998AspIle: 1.998 ± 0.048	0.693AspLys: 0.693 ± 0.03	6.701AspLeu: 6.701 ± 0.087	0.861AspMet: 0.861 ± 0.031	0.858AspAsn: 0.858 ± 0.033	4.275AspPro: 4.275 ± 0.075	1.726AspGln: 1.726 ± 0.048	3.928AspArg: 3.928 ± 0.059	2.644AspSer: 2.644 ± 0.055	2.424AspThr: 2.424 ± 0.052	5.358AspVal: 5.358 ± 0.084	0.838AspTrp: 0.838 ± 0.03	1.202AspTyr: 1.202 ± 0.04	0.0AspXaa: 0.0 ± 0.0
Glu	8.686GluAla: 8.686 ± 0.126	0.291GluCys: 0.291 ± 0.019	3.944GluAsp: 3.944 ± 0.069	4.571GluGlu: 4.571 ± 0.076	1.589GluPhe: 1.589 ± 0.043	4.903GluGly: 4.903 ± 0.086	1.966GluHis: 1.966 ± 0.043	3.18GluIle: 3.18 ± 0.067	1.111GluLys: 1.111 ± 0.042	7.577GluLeu: 7.577 ± 0.097	1.139GluMet: 1.139 ± 0.035	1.427GluAsn: 1.427 ± 0.042	4.141GluPro: 4.141 ± 0.137	2.723GluGln: 2.723 ± 0.055	5.635GluArg: 5.635 ± 0.08	3.219GluSer: 3.219 ± 0.063	3.256GluThr: 3.256 ± 0.067	5.894GluVal: 5.894 ± 0.087	0.856GluTrp: 0.856 ± 0.028	1.177GluTyr: 1.177 ± 0.035	0.0GluXaa: 0.0 ± 0.0
Phe	3.625PheAla: 3.625 ± 0.071	0.164PheCys: 0.164 ± 0.015	1.886PheAsp: 1.886 ± 0.047	1.66PheGlu: 1.66 ± 0.045	0.979PhePhe: 0.979 ± 0.037	2.849PheGly: 2.849 ± 0.067	0.58PheHis: 0.58 ± 0.025	0.961PheIle: 0.961 ± 0.036	0.336PheLys: 0.336 ± 0.02	2.693PheLeu: 2.693 ± 0.056	0.445PheMet: 0.445 ± 0.022	0.509PheAsn: 0.509 ± 0.023	1.281PhePro: 1.281 ± 0.039	0.739PheGln: 0.739 ± 0.027	1.662PheArg: 1.662 ± 0.045	1.8PheSer: 1.8 ± 0.051	2.052PheThr: 2.052 ± 0.054	2.285PheVal: 2.285 ± 0.056	0.461PheTrp: 0.461 ± 0.024	0.597PheTyr: 0.597 ± 0.028	0.0PheXaa: 0.0 ± 0.0
Gly	11.674GlyAla: 11.674 ± 0.135	0.509GlyCys: 0.509 ± 0.022	4.763GlyAsp: 4.763 ± 0.084	6.303GlyGlu: 6.303 ± 0.113	2.839GlyPhe: 2.839 ± 0.063	7.969GlyGly: 7.969 ± 0.131	2.069GlyHis: 2.069 ± 0.048	3.839GlyIle: 3.839 ± 0.065	1.769GlyLys: 1.769 ± 0.053	9.05GlyLeu: 9.05 ± 0.119	2.099GlyMet: 2.099 ± 0.048	1.637GlyAsn: 1.637 ± 0.049	4.727GlyPro: 4.727 ± 0.08	3.102GlyGln: 3.102 ± 0.061	6.452GlyArg: 6.452 ± 0.085	5.628GlySer: 5.628 ± 0.085	5.492GlyThr: 5.492 ± 0.078	7.759GlyVal: 7.759 ± 0.108	1.653GlyTrp: 1.653 ± 0.045	2.177GlyTyr: 2.177 ± 0.051	0.0GlyXaa: 0.0 ± 0.0
His	2.745HisAla: 2.745 ± 0.06	0.147HisCys: 0.147 ± 0.012	1.379HisAsp: 1.379 ± 0.042	1.441HisGlu: 1.441 ± 0.039	0.576HisPhe: 0.576 ± 0.024	2.237HisGly: 2.237 ± 0.05	0.722HisHis: 0.722 ± 0.032	0.685HisIle: 0.685 ± 0.026	0.235HisLys: 0.235 ± 0.016	2.536HisLeu: 2.536 ± 0.056	0.341HisMet: 0.341 ± 0.019	0.344HisAsn: 0.344 ± 0.022	1.595HisPro: 1.595 ± 0.049	0.767HisGln: 0.767 ± 0.028	1.947HisArg: 1.947 ± 0.049	1.107HisSer: 1.107 ± 0.036	1.169HisThr: 1.169 ± 0.032	1.755HisVal: 1.755 ± 0.049	0.357HisTrp: 0.357 ± 0.018	0.483HisTyr: 0.483 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	5.711IleAla: 5.711 ± 0.088	0.271IleCys: 0.271 ± 0.016	2.881IleAsp: 2.881 ± 0.054	2.75IleGlu: 2.75 ± 0.056	1.073IlePhe: 1.073 ± 0.04	3.846IleGly: 3.846 ± 0.075	0.737IleHis: 0.737 ± 0.026	1.491IleIle: 1.491 ± 0.042	0.612IleLys: 0.612 ± 0.025	3.416IleLeu: 3.416 ± 0.061	0.616IleMet: 0.616 ± 0.026	0.812IleAsn: 0.812 ± 0.032	2.161IlePro: 2.161 ± 0.052	0.869IleGln: 0.869 ± 0.03	2.371IleArg: 2.371 ± 0.051	2.358IleSer: 2.358 ± 0.054	2.524IleThr: 2.524 ± 0.063	3.42IleVal: 3.42 ± 0.067	0.485IleTrp: 0.485 ± 0.024	0.755IleTyr: 0.755 ± 0.03	0.0IleXaa: 0.0 ± 0.0
Lys	1.852LysAla: 1.852 ± 0.054	0.05LysCys: 0.05 ± 0.007	0.842LysAsp: 0.842 ± 0.035	0.817LysGlu: 0.817 ± 0.03	0.283LysPhe: 0.283 ± 0.018	1.13LysGly: 1.13 ± 0.042	0.38LysHis: 0.38 ± 0.021	0.637LysIle: 0.637 ± 0.026	0.572LysLys: 0.572 ± 0.031	1.416LysLeu: 1.416 ± 0.046	0.259LysMet: 0.259 ± 0.017	0.405LysAsn: 0.405 ± 0.022	0.953LysPro: 0.953 ± 0.039	0.554LysGln: 0.554 ± 0.024	1.208LysArg: 1.208 ± 0.039	0.855LysSer: 0.855 ± 0.033	0.939LysThr: 0.939 ± 0.036	1.275LysVal: 1.275 ± 0.039	0.158LysTrp: 0.158 ± 0.013	0.343LysTyr: 0.343 ± 0.02	0.0LysXaa: 0.0 ± 0.0
Leu	15.496LeuAla: 15.496 ± 0.165	0.582LeuCys: 0.582 ± 0.028	6.553LeuAsp: 6.553 ± 0.096	6.168LeuGlu: 6.168 ± 0.086	2.509LeuPhe: 2.509 ± 0.066	9.544LeuGly: 9.544 ± 0.101	2.133LeuHis: 2.133 ± 0.049	4.059LeuIle: 4.059 ± 0.08	1.347LeuLys: 1.347 ± 0.046	10.653LeuLeu: 10.653 ± 0.14	1.809LeuMet: 1.809 ± 0.047	1.718LeuAsn: 1.718 ± 0.047	6.112LeuPro: 6.112 ± 0.071	2.657LeuGln: 2.657 ± 0.055	7.952LeuArg: 7.952 ± 0.111	5.931LeuSer: 5.931 ± 0.089	6.816LeuThr: 6.816 ± 0.089	8.749LeuVal: 8.749 ± 0.123	1.34LeuTrp: 1.34 ± 0.044	1.591LeuTyr: 1.591 ± 0.044	0.0LeuXaa: 0.0 ± 0.0
Met	2.564MetAla: 2.564 ± 0.053	0.109MetCys: 0.109 ± 0.009	0.938MetAsp: 0.938 ± 0.031	0.811MetGlu: 0.811 ± 0.029	0.481MetPhe: 0.481 ± 0.021	1.445MetGly: 1.445 ± 0.037	0.353MetHis: 0.353 ± 0.018	0.839MetIle: 0.839 ± 0.029	0.333MetLys: 0.333 ± 0.019	1.993MetLeu: 1.993 ± 0.05	0.367MetMet: 0.367 ± 0.016	0.484MetAsn: 0.484 ± 0.024	1.146MetPro: 1.146 ± 0.04	0.485MetGln: 0.485 ± 0.022	1.533MetArg: 1.533 ± 0.038	1.547MetSer: 1.547 ± 0.031	1.709MetThr: 1.709 ± 0.04	1.551MetVal: 1.551 ± 0.037	0.226MetTrp: 0.226 ± 0.014	0.31MetTyr: 0.31 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	2.093AsnAla: 2.093 ± 0.048	0.086AsnCys: 0.086 ± 0.01	1.014AsnAsp: 1.014 ± 0.032	0.997AsnGlu: 0.997 ± 0.031	0.593AsnPhe: 0.593 ± 0.024	1.622AsnGly: 1.622 ± 0.047	0.418AsnHis: 0.418 ± 0.023	0.703AsnIle: 0.703 ± 0.027	0.251AsnLys: 0.251 ± 0.021	1.827AsnLeu: 1.827 ± 0.048	0.345AsnMet: 0.345 ± 0.017	0.425AsnAsn: 0.425 ± 0.022	1.397AsnPro: 1.397 ± 0.038	0.525AsnGln: 0.525 ± 0.026	1.158AsnArg: 1.158 ± 0.032	0.99AsnSer: 0.99 ± 0.033	1.11AsnThr: 1.11 ± 0.049	1.485AsnVal: 1.485 ± 0.049	0.275AsnTrp: 0.275 ± 0.019	0.488AsnTyr: 0.488 ± 0.025	0.0AsnXaa: 0.0 ± 0.0
Pro	8.176ProAla: 8.176 ± 0.122	0.207ProCys: 0.207 ± 0.014	3.69ProAsp: 3.69 ± 0.068	5.08ProGlu: 5.08 ± 0.082	1.446ProPhe: 1.446 ± 0.038	6.331ProGly: 6.331 ± 0.093	1.349ProHis: 1.349 ± 0.038	1.702ProIle: 1.702 ± 0.042	0.726ProLys: 0.726 ± 0.034	4.776ProLeu: 4.776 ± 0.086	1.042ProMet: 1.042 ± 0.035	0.87ProAsn: 0.87 ± 0.032	3.031ProPro: 3.031 ± 0.086	1.942ProGln: 1.942 ± 0.055	3.557ProArg: 3.557 ± 0.065	3.183ProSer: 3.183 ± 0.06	3.137ProThr: 3.137 ± 0.128	4.963ProVal: 4.963 ± 0.081	0.935ProTrp: 0.935 ± 0.031	1.061ProTyr: 1.061 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	4.243GlnAla: 4.243 ± 0.074	0.139GlnCys: 0.139 ± 0.014	1.57GlnAsp: 1.57 ± 0.046	1.839GlnGlu: 1.839 ± 0.046	0.745GlnPhe: 0.745 ± 0.029	2.321GlnGly: 2.321 ± 0.051	0.784GlnHis: 0.784 ± 0.032	1.458GlnIle: 1.458 ± 0.042	0.398GlnLys: 0.398 ± 0.019	3.255GlnLeu: 3.255 ± 0.065	0.627GlnMet: 0.627 ± 0.03	0.585GlnAsn: 0.585 ± 0.024	1.811GlnPro: 1.811 ± 0.048	1.324GlnGln: 1.324 ± 0.045	2.794GlnArg: 2.794 ± 0.064	1.471GlnSer: 1.471 ± 0.044	1.483GlnThr: 1.483 ± 0.039	2.88GlnVal: 2.88 ± 0.057	0.547GlnTrp: 0.547 ± 0.023	0.605GlnTyr: 0.605 ± 0.028	0.0GlnXaa: 0.0 ± 0.0
Arg	9.38ArgAla: 9.38 ± 0.136	0.395ArgCys: 0.395 ± 0.023	3.687ArgAsp: 3.687 ± 0.069	5.142ArgGlu: 5.142 ± 0.087	2.047ArgPhe: 2.047 ± 0.052	5.54ArgGly: 5.54 ± 0.086	1.9ArgHis: 1.9 ± 0.048	3.027ArgIle: 3.027 ± 0.059	1.24ArgLys: 1.24 ± 0.044	7.629ArgLeu: 7.629 ± 0.115	1.749ArgMet: 1.749 ± 0.044	1.249ArgAsn: 1.249 ± 0.035	3.977ArgPro: 3.977 ± 0.065	2.416ArgGln: 2.416 ± 0.05	7.144ArgArg: 7.144 ± 0.141	4.331ArgSer: 4.331 ± 0.083	4.294ArgThr: 4.294 ± 0.062	5.528ArgVal: 5.528 ± 0.072	1.385ArgTrp: 1.385 ± 0.042	1.657ArgTyr: 1.657 ± 0.044	0.0ArgXaa: 0.0 ± 0.0
Ser	7.66SerAla: 7.66 ± 0.089	0.304SerCys: 0.304 ± 0.018	2.856SerAsp: 2.856 ± 0.052	3.393SerGlu: 3.393 ± 0.065	1.794SerPhe: 1.794 ± 0.05	6.194SerGly: 6.194 ± 0.094	1.139SerHis: 1.139 ± 0.033	2.053SerIle: 2.053 ± 0.049	0.767SerLys: 0.767 ± 0.03	5.331SerLeu: 5.331 ± 0.077	1.243SerMet: 1.243 ± 0.039	0.959SerAsn: 0.959 ± 0.033	3.268SerPro: 3.268 ± 0.062	1.549SerGln: 1.549 ± 0.04	3.86SerArg: 3.86 ± 0.066	3.479SerSer: 3.479 ± 0.075	3.373SerThr: 3.373 ± 0.064	4.361SerVal: 4.361 ± 0.071	1.053SerTrp: 1.053 ± 0.036	1.267SerTyr: 1.267 ± 0.043	0.0SerXaa: 0.0 ± 0.0
Thr	7.937ThrAla: 7.937 ± 0.1	0.295ThrCys: 0.295 ± 0.017	3.327ThrAsp: 3.327 ± 0.072	3.8ThrGlu: 3.8 ± 0.112	1.833ThrPhe: 1.833 ± 0.048	6.105ThrGly: 6.105 ± 0.098	1.103ThrHis: 1.103 ± 0.032	2.335ThrIle: 2.335 ± 0.059	0.833ThrLys: 0.833 ± 0.03	5.805ThrLeu: 5.805 ± 0.079	1.103ThrMet: 1.103 ± 0.033	1.044ThrAsn: 1.044 ± 0.046	3.548ThrPro: 3.548 ± 0.071	1.481ThrGln: 1.481 ± 0.048	3.47ThrArg: 3.47 ± 0.068	3.401ThrSer: 3.401 ± 0.057	3.713ThrThr: 3.713 ± 0.064	5.581ThrVal: 5.581 ± 0.087	0.981ThrTrp: 0.981 ± 0.029	1.278ThrTyr: 1.278 ± 0.04	0.0ThrXaa: 0.0 ± 0.0
Val	11.276ValAla: 11.276 ± 0.137	0.5ValCys: 0.5 ± 0.023	5.166ValAsp: 5.166 ± 0.076	5.45ValGlu: 5.45 ± 0.09	2.378ValPhe: 2.378 ± 0.057	6.448ValGly: 6.448 ± 0.095	1.929ValHis: 1.929 ± 0.049	3.896ValIle: 3.896 ± 0.07	1.223ValLys: 1.223 ± 0.044	9.925ValLeu: 9.925 ± 0.12	1.627ValMet: 1.627 ± 0.041	1.608ValAsn: 1.608 ± 0.046	4.866ValPro: 4.866 ± 0.074	2.192ValGln: 2.192 ± 0.049	6.208ValArg: 6.208 ± 0.094	4.842ValSer: 4.842 ± 0.076	5.731ValThr: 5.731 ± 0.114	8.47ValVal: 8.47 ± 0.122	1.068ValTrp: 1.068 ± 0.036	1.394ValTyr: 1.394 ± 0.036	0.0ValXaa: 0.0 ± 0.0
Trp	1.569TrpAla: 1.569 ± 0.037	0.119TrpCys: 0.119 ± 0.01	0.861TrpAsp: 0.861 ± 0.029	0.863TrpGlu: 0.863 ± 0.031	0.502TrpPhe: 0.502 ± 0.026	1.091TrpGly: 1.091 ± 0.038	0.376TrpHis: 0.376 ± 0.019	0.634TrpIle: 0.634 ± 0.027	0.222TrpLys: 0.222 ± 0.014	1.73TrpLeu: 1.73 ± 0.051	0.335TrpMet: 0.335 ± 0.018	0.446TrpAsn: 0.446 ± 0.023	0.781TrpPro: 0.781 ± 0.03	0.666TrpGln: 0.666 ± 0.028	1.379TrpArg: 1.379 ± 0.045	1.046TrpSer: 1.046 ± 0.036	0.945TrpThr: 0.945 ± 0.033	1.107TrpVal: 1.107 ± 0.036	0.401TrpTrp: 0.401 ± 0.023	0.313TrpTyr: 0.313 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.348TyrAla: 2.348 ± 0.05	0.134TyrCys: 0.134 ± 0.014	1.24TyrAsp: 1.24 ± 0.04	1.221TyrGlu: 1.221 ± 0.037	0.635TyrPhe: 0.635 ± 0.027	1.829TyrGly: 1.829 ± 0.045	0.357TyrHis: 0.357 ± 0.02	0.576TyrIle: 0.576 ± 0.028	0.244TyrLys: 0.244 ± 0.017	2.316TyrLeu: 2.316 ± 0.05	0.257TyrMet: 0.257 ± 0.016	0.411TyrAsn: 0.411 ± 0.023	1.081TyrPro: 1.081 ± 0.03	0.623TyrGln: 0.623 ± 0.025	1.703TyrArg: 1.703 ± 0.047	1.114TyrSer: 1.114 ± 0.039	1.075TyrThr: 1.075 ± 0.037	1.543TyrVal: 1.543 ± 0.043	0.33TyrTrp: 0.33 ± 0.02	0.458TyrTyr: 0.458 ± 0.023	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2844 proteins (992085 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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