Human papillomavirus type 63

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Mupapillomavirus; Mupapillomavirus 2

Average proteome isoelectric point is 6.32

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 8 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>sp|Q07861|VL1_HPV63 Major capsid protein L1 OS=Human papillomavirus type 63 OX=28311 GN=L1 PE=3 SV=1
MM1 pKa = 8.43VGEE4 pKa = 4.26QPNIGDD10 pKa = 3.93LVSQEE15 pKa = 4.23EE16 pKa = 4.4PSVLDD21 pKa = 3.64LNCYY25 pKa = 9.73EE26 pKa = 5.5DD27 pKa = 4.04IPAEE31 pKa = 4.19EE32 pKa = 4.82EE33 pKa = 3.91EE34 pKa = 4.47SEE36 pKa = 4.27YY37 pKa = 10.49PYY39 pKa = 10.91AIVLPCGLCDD49 pKa = 3.32QLLRR53 pKa = 11.84LTCVSDD59 pKa = 4.3LSTLTRR65 pKa = 11.84LEE67 pKa = 3.89EE68 pKa = 4.12LLLGSLRR75 pKa = 11.84IVCPLCAIRR84 pKa = 11.84HH85 pKa = 4.55QRR87 pKa = 11.84HH88 pKa = 4.89

Molecular weight: 9.87 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>sp|Q07847|VE1_HPV63 Replication protein E1 OS=Human papillomavirus type 63 OX=28311 GN=E1 PE=3 SV=1
MM1 pKa = 7.77KK2 pKa = 9.51LTILTKK8 pKa = 10.19RR9 pKa = 11.84FRR11 pKa = 11.84SSSPLRR17 pKa = 11.84TSGSPTDD24 pKa = 4.12TNPATQGQSTQTARR38 pKa = 11.84KK39 pKa = 9.71AEE41 pKa = 4.42TKK43 pKa = 10.29GSRR46 pKa = 11.84HH47 pKa = 5.82HH48 pKa = 6.81PKK50 pKa = 10.25SPAVRR55 pKa = 11.84KK56 pKa = 9.16RR57 pKa = 11.84RR58 pKa = 11.84PYY60 pKa = 9.11GRR62 pKa = 11.84RR63 pKa = 11.84RR64 pKa = 11.84SRR66 pKa = 11.84SPRR69 pKa = 11.84DD70 pKa = 3.19TTLRR74 pKa = 11.84RR75 pKa = 11.84GEE77 pKa = 4.32GEE79 pKa = 4.03SARR82 pKa = 11.84ASAGSGEE89 pKa = 4.11RR90 pKa = 11.84VAFISPGDD98 pKa = 3.59VGTSTRR104 pKa = 11.84SPPKK108 pKa = 10.02GGQSRR113 pKa = 11.84LRR115 pKa = 11.84RR116 pKa = 11.84LIQEE120 pKa = 4.19ARR122 pKa = 11.84DD123 pKa = 3.62PPIICLKK130 pKa = 10.6GGPNQLKK137 pKa = 9.9CLRR140 pKa = 11.84YY141 pKa = 9.61RR142 pKa = 11.84IKK144 pKa = 10.82ASNSSDD150 pKa = 3.42FEE152 pKa = 4.89SISTTWHH159 pKa = 5.37WVHH162 pKa = 6.35NKK164 pKa = 8.2CTDD167 pKa = 3.49RR168 pKa = 11.84VGHH171 pKa = 6.2ARR173 pKa = 11.84MLVRR177 pKa = 11.84FISTEE182 pKa = 3.62QRR184 pKa = 11.84DD185 pKa = 3.6RR186 pKa = 11.84FLDD189 pKa = 3.52KK190 pKa = 11.1VVVPKK195 pKa = 10.47SVSVILGAFDD205 pKa = 3.95GSS207 pKa = 3.59

Molecular weight: 22.98 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

8

0

8

2580

88

618

322.5

36.41

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.969 ± 0.434

1.822 ± 0.572

6.395 ± 0.307

6.085 ± 0.644

3.76 ± 0.445

5.581 ± 0.772

2.016 ± 0.192

5.349 ± 0.73

4.574 ± 0.827

8.566 ± 0.933

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.705 ± 0.31

4.457 ± 0.665

6.202 ± 0.969

4.729 ± 0.355

7.403 ± 1.207

8.295 ± 0.814

6.318 ± 0.561

6.279 ± 0.357

1.24 ± 0.354

3.256 ± 0.25
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski