Latimeria chalumnae (Coelacanth)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; Sarcopterygii; Coelacanthimorpha; Coelacanthiformes; Coelacanthidae; Latimeria

Average proteome isoelectric point is 6.75

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 23431 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|H3AV62|H3AV62_LATCH G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Latimeria chalumnae OX=7897 PE=3 SV=1
MM1 pKa = 7.86EE2 pKa = 5.02FQQLVDD8 pKa = 5.63IADD11 pKa = 3.8KK12 pKa = 10.17WCSNTPFEE20 pKa = 5.67LIAAEE25 pKa = 4.02EE26 pKa = 4.38AEE28 pKa = 4.32TRR30 pKa = 11.84LDD32 pKa = 4.43FYY34 pKa = 11.42ADD36 pKa = 3.72PGVSFYY42 pKa = 10.98VLCPDD47 pKa = 4.55NGSGDD52 pKa = 3.85NFHH55 pKa = 6.35VWSEE59 pKa = 4.48SEE61 pKa = 3.97DD62 pKa = 3.63CLPFLQLAQDD72 pKa = 4.45YY73 pKa = 10.71ISSCGKK79 pKa = 8.61KK80 pKa = 7.81TLSEE84 pKa = 3.84ILEE87 pKa = 4.28KK88 pKa = 10.82VFKK91 pKa = 10.7SFKK94 pKa = 9.93PLLGLPDD101 pKa = 3.59VDD103 pKa = 5.25DD104 pKa = 6.2DD105 pKa = 5.32AFEE108 pKa = 5.6DD109 pKa = 3.97YY110 pKa = 10.98NADD113 pKa = 3.62VEE115 pKa = 4.48EE116 pKa = 4.72EE117 pKa = 4.21EE118 pKa = 5.26PEE120 pKa = 4.6ADD122 pKa = 3.62HH123 pKa = 6.03QQMGISQQQ131 pKa = 3.15

Molecular weight: 14.84 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|H3B7D2|H3B7D2_LATCH Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Latimeria chalumnae OX=7897 GN=RPN1 PE=3 SV=1
PP1 pKa = 7.75RR2 pKa = 11.84LLLSTQTLNPPRR14 pKa = 11.84PLLSTQTLNPPRR26 pKa = 11.84PLLSTQTLNPPRR38 pKa = 11.84PLLSTQTLNPSRR50 pKa = 11.84PPLSTQTLNPSRR62 pKa = 11.84PPLSTQTLNPPRR74 pKa = 11.84ALLSTQTLNPPRR86 pKa = 11.84SLSTQTLNPPRR97 pKa = 11.84SLLSTQTLNPPRR109 pKa = 11.84PPLSTQTLNPPRR121 pKa = 11.84PPLSTQTLNPPRR133 pKa = 11.84PPLSTQTLNPPRR145 pKa = 11.84PPLSTQTLNPPRR157 pKa = 11.84PLLSMQTLNPSRR169 pKa = 11.84PLLSTT174 pKa = 3.87

Molecular weight: 19.0 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

19568

3863

23431

12138361

15

21846

518.0

58.29

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.11 ± 0.011

2.285 ± 0.015

4.946 ± 0.01

7.092 ± 0.022

3.975 ± 0.012

5.783 ± 0.021

2.521 ± 0.008

5.15 ± 0.012

6.625 ± 0.018

9.645 ± 0.021

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.273 ± 0.006

4.346 ± 0.011

5.121 ± 0.018

4.707 ± 0.015

5.126 ± 0.013

8.288 ± 0.019

5.578 ± 0.012

6.241 ± 0.013

1.193 ± 0.005

2.994 ± 0.009
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski