Amino acid dipepetide frequency for Cragig virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.17AlaAla: 6.17 ± 2.303
0.823AlaCys: 0.823 ± 0.456
3.291AlaAsp: 3.291 ± 0.72
3.702AlaGlu: 3.702 ± 0.492
2.468AlaPhe: 2.468 ± 1.368
6.17AlaGly: 6.17 ± 2.303
0.823AlaHis: 0.823 ± 0.18
3.702AlaIle: 3.702 ± 0.492
2.879AlaLys: 2.879 ± 1.596
5.759AlaLeu: 5.759 ± 0.624
1.234AlaMet: 1.234 ± 0.588
3.702AlaAsn: 3.702 ± 2.399
3.291AlaPro: 3.291 ± 2.627
2.057AlaGln: 2.057 ± 0.132
2.468AlaArg: 2.468 ± 0.732
3.702AlaSer: 3.702 ± 1.128
6.17AlaThr: 6.17 ± 1.032
4.114AlaVal: 4.114 ± 0.9
0.823AlaTrp: 0.823 ± 0.456
1.645AlaTyr: 1.645 ± 0.36
0.0AlaXaa: 0.0 ± 0.0
Cys
2.468CysAla: 2.468 ± 0.732
0.411CysCys: 0.411 ± 0.228
0.0CysAsp: 0.0 ± 0.0
0.411CysGlu: 0.411 ± 0.228
1.234CysPhe: 1.234 ± 0.048
1.234CysGly: 1.234 ± 0.684
0.823CysHis: 0.823 ± 0.18
0.823CysIle: 0.823 ± 0.18
1.234CysLys: 1.234 ± 0.048
0.411CysLeu: 0.411 ± 0.228
0.411CysMet: 0.411 ± 0.228
0.0CysAsn: 0.0 ± 0.0
0.823CysPro: 0.823 ± 0.456
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.234CysSer: 1.234 ± 0.048
0.411CysThr: 0.411 ± 0.228
2.057CysVal: 2.057 ± 0.132
0.411CysTrp: 0.411 ± 0.228
0.823CysTyr: 0.823 ± 0.456
0.0CysXaa: 0.0 ± 0.0
Asp
4.114AspAla: 4.114 ± 1.008
1.234AspCys: 1.234 ± 0.684
3.702AspAsp: 3.702 ± 0.144
2.879AspGlu: 2.879 ± 0.96
4.114AspPhe: 4.114 ± 0.264
1.645AspGly: 1.645 ± 0.276
1.234AspHis: 1.234 ± 0.684
4.114AspIle: 4.114 ± 0.264
4.114AspLys: 4.114 ± 2.279
5.759AspLeu: 5.759 ± 0.648
0.411AspMet: 0.411 ± 0.408
2.468AspAsn: 2.468 ± 0.096
3.291AspPro: 3.291 ± 1.992
1.645AspGln: 1.645 ± 0.912
2.057AspArg: 2.057 ± 0.132
3.702AspSer: 3.702 ± 1.128
4.525AspThr: 4.525 ± 1.944
4.525AspVal: 4.525 ± 0.672
0.411AspTrp: 0.411 ± 0.228
1.234AspTyr: 1.234 ± 0.048
0.0AspXaa: 0.0 ± 0.0
Glu
1.645GluAla: 1.645 ± 0.276
0.823GluCys: 0.823 ± 0.456
1.645GluAsp: 1.645 ± 0.36
4.525GluGlu: 4.525 ± 1.236
0.823GluPhe: 0.823 ± 0.18
3.291GluGly: 3.291 ± 0.084
0.411GluHis: 0.411 ± 0.228
2.879GluIle: 2.879 ± 0.324
3.291GluLys: 3.291 ± 0.084
6.17GluLeu: 6.17 ± 0.24
0.411GluMet: 0.411 ± 0.228
1.234GluAsn: 1.234 ± 0.588
0.823GluPro: 0.823 ± 0.18
1.645GluGln: 1.645 ± 0.276
1.645GluArg: 1.645 ± 0.276
3.702GluSer: 3.702 ± 0.78
2.879GluThr: 2.879 ± 0.96
4.525GluVal: 4.525 ± 1.308
1.645GluTrp: 1.645 ± 0.276
2.879GluTyr: 2.879 ± 0.96
0.0GluXaa: 0.0 ± 0.0
Phe
3.702PheAla: 3.702 ± 0.492
0.0PheCys: 0.0 ± 0.0
4.114PheAsp: 4.114 ± 0.264
0.823PheGlu: 0.823 ± 0.18
4.114PhePhe: 4.114 ± 1.008
4.114PheGly: 4.114 ± 0.372
1.234PheHis: 1.234 ± 0.588
2.468PheIle: 2.468 ± 1.368
2.468PheLys: 2.468 ± 0.732
6.17PheLeu: 6.17 ± 0.396
1.234PheMet: 1.234 ± 0.048
2.468PheAsn: 2.468 ± 0.732
2.879PhePro: 2.879 ± 0.96
3.291PheGln: 3.291 ± 0.084
2.468PheArg: 2.468 ± 0.096
4.936PheSer: 4.936 ± 1.716
5.348PheThr: 5.348 ± 1.692
3.291PheVal: 3.291 ± 0.084
0.823PheTrp: 0.823 ± 0.18
2.057PheTyr: 2.057 ± 0.132
0.0PheXaa: 0.0 ± 0.0
Gly
4.525GlyAla: 4.525 ± 1.944
2.057GlyCys: 2.057 ± 0.768
5.759GlyAsp: 5.759 ± 0.012
3.702GlyGlu: 3.702 ± 1.128
3.291GlyPhe: 3.291 ± 0.72
4.936GlyGly: 4.936 ± 1.08
0.411GlyHis: 0.411 ± 0.228
4.525GlyIle: 4.525 ± 0.6
2.468GlyLys: 2.468 ± 0.096
3.291GlyLeu: 3.291 ± 1.824
1.645GlyMet: 1.645 ± 0.36
3.291GlyAsn: 3.291 ± 0.084
2.879GlyPro: 2.879 ± 1.584
0.0GlyGln: 0.0 ± 0.0
3.291GlyArg: 3.291 ± 0.084
5.759GlySer: 5.759 ± 0.648
6.17GlyThr: 6.17 ± 0.396
5.348GlyVal: 5.348 ± 1.488
0.823GlyTrp: 0.823 ± 0.18
2.879GlyTyr: 2.879 ± 0.324
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.411HisCys: 0.411 ± 0.228
1.645HisAsp: 1.645 ± 0.912
0.823HisGlu: 0.823 ± 0.456
1.234HisPhe: 1.234 ± 0.048
1.645HisGly: 1.645 ± 0.912
0.0HisHis: 0.0 ± 0.0
0.823HisIle: 0.823 ± 0.18
2.057HisLys: 2.057 ± 0.504
3.702HisLeu: 3.702 ± 0.144
1.645HisMet: 1.645 ± 0.912
1.234HisAsn: 1.234 ± 0.048
0.823HisPro: 0.823 ± 0.456
1.234HisGln: 1.234 ± 0.684
0.823HisArg: 0.823 ± 0.18
2.468HisSer: 2.468 ± 0.54
1.234HisThr: 1.234 ± 0.048
1.234HisVal: 1.234 ± 0.048
0.823HisTrp: 0.823 ± 0.456
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.702IleAla: 3.702 ± 0.492
1.234IleCys: 1.234 ± 0.048
3.702IleAsp: 3.702 ± 0.144
1.645IleGlu: 1.645 ± 0.276
4.114IlePhe: 4.114 ± 0.264
3.702IleGly: 3.702 ± 0.492
1.234IleHis: 1.234 ± 0.048
2.879IleIle: 2.879 ± 0.324
0.823IleLys: 0.823 ± 0.456
6.582IleLeu: 6.582 ± 1.104
1.645IleMet: 1.645 ± 0.912
4.114IleAsn: 4.114 ± 0.264
2.879IlePro: 2.879 ± 0.96
1.645IleGln: 1.645 ± 0.276
2.057IleArg: 2.057 ± 0.768
5.759IleSer: 5.759 ± 1.26
2.879IleThr: 2.879 ± 0.312
4.525IleVal: 4.525 ± 1.236
1.234IleTrp: 1.234 ± 0.684
1.234IleTyr: 1.234 ± 0.684
0.0IleXaa: 0.0 ± 0.0
Lys
1.234LysAla: 1.234 ± 0.048
0.823LysCys: 0.823 ± 0.456
5.348LysAsp: 5.348 ± 1.692
2.879LysGlu: 2.879 ± 0.324
2.879LysPhe: 2.879 ± 0.324
3.702LysGly: 3.702 ± 1.416
1.645LysHis: 1.645 ± 0.36
4.525LysIle: 4.525 ± 1.236
2.468LysLys: 2.468 ± 0.732
4.525LysLeu: 4.525 ± 0.672
1.234LysMet: 1.234 ± 0.684
1.645LysAsn: 1.645 ± 0.912
2.468LysPro: 2.468 ± 0.096
3.702LysGln: 3.702 ± 1.416
2.879LysArg: 2.879 ± 0.96
4.936LysSer: 4.936 ± 1.464
1.645LysThr: 1.645 ± 0.276
2.468LysVal: 2.468 ± 0.732
1.234LysTrp: 1.234 ± 0.048
2.057LysTyr: 2.057 ± 0.132
0.0LysXaa: 0.0 ± 0.0
Leu
6.582LeuAla: 6.582 ± 0.168
1.645LeuCys: 1.645 ± 0.276
5.348LeuAsp: 5.348 ± 1.692
3.702LeuGlu: 3.702 ± 0.144
3.702LeuPhe: 3.702 ± 0.78
5.348LeuGly: 5.348 ± 0.852
1.645LeuHis: 1.645 ± 0.912
4.936LeuIle: 4.936 ± 2.1
5.348LeuLys: 5.348 ± 1.056
4.936LeuLeu: 4.936 ± 1.464
2.057LeuMet: 2.057 ± 0.504
3.702LeuAsn: 3.702 ± 1.764
5.759LeuPro: 5.759 ± 0.648
1.234LeuGln: 1.234 ± 0.048
3.291LeuArg: 3.291 ± 1.824
9.461LeuSer: 9.461 ± 0.156
8.227LeuThr: 8.227 ± 1.8
8.227LeuVal: 8.227 ± 0.108
0.0LeuTrp: 0.0 ± 0.0
2.468LeuTyr: 2.468 ± 0.732
0.0LeuXaa: 0.0 ± 0.0
Met
1.645MetAla: 1.645 ± 0.996
0.411MetCys: 0.411 ± 0.228
1.645MetAsp: 1.645 ± 0.36
1.645MetGlu: 1.645 ± 0.276
1.234MetPhe: 1.234 ± 0.684
1.234MetGly: 1.234 ± 0.048
1.234MetHis: 1.234 ± 0.048
2.057MetIle: 2.057 ± 0.132
2.468MetLys: 2.468 ± 0.732
0.0MetLeu: 0.0 ± 0.0
0.823MetMet: 0.823 ± 0.456
2.057MetAsn: 2.057 ± 0.504
0.411MetPro: 0.411 ± 0.408
0.0MetGln: 0.0 ± 0.0
1.234MetArg: 1.234 ± 1.224
2.879MetSer: 2.879 ± 0.312
1.645MetThr: 1.645 ± 0.912
1.645MetVal: 1.645 ± 0.36
0.0MetTrp: 0.0 ± 0.0
1.645MetTyr: 1.645 ± 0.276
0.0MetXaa: 0.0 ± 0.0
Asn
4.525AsnAla: 4.525 ± 1.944
0.411AsnCys: 0.411 ± 0.228
2.879AsnAsp: 2.879 ± 0.96
2.057AsnGlu: 2.057 ± 0.132
4.525AsnPhe: 4.525 ± 0.036
3.702AsnGly: 3.702 ± 0.492
1.234AsnHis: 1.234 ± 0.684
1.645AsnIle: 1.645 ± 0.912
1.234AsnLys: 1.234 ± 0.588
2.879AsnLeu: 2.879 ± 0.96
1.234AsnMet: 1.234 ± 0.588
2.057AsnAsn: 2.057 ± 1.404
2.468AsnPro: 2.468 ± 0.54
0.411AsnGln: 0.411 ± 0.408
1.645AsnArg: 1.645 ± 0.276
3.291AsnSer: 3.291 ± 0.084
3.291AsnThr: 3.291 ± 1.356
2.468AsnVal: 2.468 ± 0.096
0.0AsnTrp: 0.0 ± 0.0
1.645AsnTyr: 1.645 ± 1.632
0.0AsnXaa: 0.0 ± 0.0
Pro
3.702ProAla: 3.702 ± 3.035
0.411ProCys: 0.411 ± 0.408
4.525ProAsp: 4.525 ± 0.036
1.234ProGlu: 1.234 ± 0.048
4.525ProPhe: 4.525 ± 0.036
3.702ProGly: 3.702 ± 0.144
0.823ProHis: 0.823 ± 0.18
2.057ProIle: 2.057 ± 0.768
2.057ProLys: 2.057 ± 1.14
5.348ProLeu: 5.348 ± 0.42
2.468ProMet: 2.468 ± 0.366
0.0ProAsn: 0.0 ± 0.0
2.057ProPro: 2.057 ± 0.504
0.823ProGln: 0.823 ± 0.18
2.057ProArg: 2.057 ± 0.132
2.879ProSer: 2.879 ± 0.324
2.879ProThr: 2.879 ± 2.219
2.057ProVal: 2.057 ± 0.132
0.411ProTrp: 0.411 ± 0.408
3.702ProTyr: 3.702 ± 1.764
0.0ProXaa: 0.0 ± 0.0
Gln
1.645GlnAla: 1.645 ± 0.912
0.823GlnCys: 0.823 ± 0.18
1.234GlnAsp: 1.234 ± 0.684
1.234GlnGlu: 1.234 ± 0.048
1.234GlnPhe: 1.234 ± 0.684
0.823GlnGly: 0.823 ± 0.456
0.823GlnHis: 0.823 ± 0.456
1.645GlnIle: 1.645 ± 0.996
1.645GlnLys: 1.645 ± 0.36
4.114GlnLeu: 4.114 ± 0.372
0.823GlnMet: 0.823 ± 0.816
0.411GlnAsn: 0.411 ± 0.408
1.234GlnPro: 1.234 ± 0.588
2.057GlnGln: 2.057 ± 1.14
1.645GlnArg: 1.645 ± 0.996
4.525GlnSer: 4.525 ± 0.036
1.234GlnThr: 1.234 ± 0.684
1.645GlnVal: 1.645 ± 0.276
1.645GlnTrp: 1.645 ± 0.276
1.645GlnTyr: 1.645 ± 0.996
0.0GlnXaa: 0.0 ± 0.0
Arg
3.291ArgAla: 3.291 ± 0.72
0.0ArgCys: 0.0 ± 0.0
1.645ArgAsp: 1.645 ± 0.276
2.057ArgGlu: 2.057 ± 0.504
2.879ArgPhe: 2.879 ± 0.324
2.057ArgGly: 2.057 ± 0.132
0.411ArgHis: 0.411 ± 0.228
1.645ArgIle: 1.645 ± 0.36
2.468ArgLys: 2.468 ± 0.732
4.525ArgLeu: 4.525 ± 1.236
1.645ArgMet: 1.645 ± 0.276
1.234ArgAsn: 1.234 ± 0.684
2.057ArgPro: 2.057 ± 0.132
1.234ArgGln: 1.234 ± 0.588
3.702ArgArg: 3.702 ± 1.416
3.702ArgSer: 3.702 ± 0.78
2.468ArgThr: 2.468 ± 0.096
2.468ArgVal: 2.468 ± 1.176
0.411ArgTrp: 0.411 ± 0.408
2.057ArgTyr: 2.057 ± 0.504
0.0ArgXaa: 0.0 ± 0.0
Ser
5.759SerAla: 5.759 ± 1.26
0.823SerCys: 0.823 ± 0.456
2.468SerAsp: 2.468 ± 1.812
4.525SerGlu: 4.525 ± 0.036
4.525SerPhe: 4.525 ± 0.672
8.227SerGly: 8.227 ± 1.8
1.645SerHis: 1.645 ± 0.912
8.227SerIle: 8.227 ± 0.108
4.525SerLys: 4.525 ± 0.6
9.05SerLeu: 9.05 ± 0.564
1.645SerMet: 1.645 ± 0.912
2.057SerAsn: 2.057 ± 0.768
1.645SerPro: 1.645 ± 0.996
4.114SerGln: 4.114 ± 2.807
2.057SerArg: 2.057 ± 0.768
6.582SerSer: 6.582 ± 0.468
4.525SerThr: 4.525 ± 0.6
4.936SerVal: 4.936 ± 1.464
0.411SerTrp: 0.411 ± 0.408
4.525SerTyr: 4.525 ± 0.036
0.0SerXaa: 0.0 ± 0.0
Thr
2.879ThrAla: 2.879 ± 0.312
0.411ThrCys: 0.411 ± 0.228
1.234ThrAsp: 1.234 ± 0.048
3.291ThrGlu: 3.291 ± 1.188
4.525ThrPhe: 4.525 ± 1.944
5.348ThrGly: 5.348 ± 2.759
3.291ThrHis: 3.291 ± 1.188
3.702ThrIle: 3.702 ± 1.128
2.879ThrLys: 2.879 ± 0.96
6.17ThrLeu: 6.17 ± 0.876
3.291ThrMet: 3.291 ± 1.356
5.348ThrAsn: 5.348 ± 0.216
3.702ThrPro: 3.702 ± 0.492
2.879ThrGln: 2.879 ± 0.96
2.468ThrArg: 2.468 ± 0.732
4.114ThrSer: 4.114 ± 0.9
3.291ThrThr: 3.291 ± 0.72
5.348ThrVal: 5.348 ± 2.123
0.0ThrTrp: 0.0 ± 0.0
2.468ThrTyr: 2.468 ± 0.096
0.0ThrXaa: 0.0 ± 0.0
Val
5.759ValAla: 5.759 ± 0.012
0.411ValCys: 0.411 ± 0.228
4.936ValAsp: 4.936 ± 1.716
4.525ValGlu: 4.525 ± 0.672
3.702ValPhe: 3.702 ± 0.144
4.525ValGly: 4.525 ± 0.036
2.879ValHis: 2.879 ± 0.96
2.879ValIle: 2.879 ± 0.324
5.348ValLys: 5.348 ± 0.42
3.702ValLeu: 3.702 ± 0.144
0.823ValMet: 0.823 ± 0.18
3.291ValAsn: 3.291 ± 0.552
5.759ValPro: 5.759 ± 1.896
2.057ValGln: 2.057 ± 0.768
3.702ValArg: 3.702 ± 1.416
4.525ValSer: 4.525 ± 1.308
5.759ValThr: 5.759 ± 1.896
6.582ValVal: 6.582 ± 1.74
0.411ValTrp: 0.411 ± 0.228
2.879ValTyr: 2.879 ± 0.312
0.0ValXaa: 0.0 ± 0.0
Trp
0.411TrpAla: 0.411 ± 0.408
1.234TrpCys: 1.234 ± 0.684
0.411TrpAsp: 0.411 ± 0.228
0.411TrpGlu: 0.411 ± 0.228
0.823TrpPhe: 0.823 ± 0.456
0.411TrpGly: 0.411 ± 0.408
0.0TrpHis: 0.0 ± 0.0
0.823TrpIle: 0.823 ± 0.456
1.234TrpLys: 1.234 ± 0.048
0.0TrpLeu: 0.0 ± 0.0
0.411TrpMet: 0.411 ± 0.228
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.823TrpGln: 0.823 ± 0.18
0.823TrpArg: 0.823 ± 0.18
2.057TrpSer: 2.057 ± 0.132
0.411TrpThr: 0.411 ± 0.408
1.234TrpVal: 1.234 ± 0.684
0.0TrpTrp: 0.0 ± 0.0
0.823TrpTyr: 0.823 ± 0.18
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.234TyrAla: 1.234 ± 0.588
0.823TyrCys: 0.823 ± 0.18
1.645TyrAsp: 1.645 ± 0.36
0.823TyrGlu: 0.823 ± 0.456
2.057TyrPhe: 2.057 ± 1.14
1.234TyrGly: 1.234 ± 0.048
2.057TyrHis: 2.057 ± 0.132
1.234TyrIle: 1.234 ± 0.048
3.291TyrLys: 3.291 ± 0.552
4.525TyrLeu: 4.525 ± 0.672
0.411TyrMet: 0.411 ± 0.33
3.291TyrAsn: 3.291 ± 0.72
2.468TyrPro: 2.468 ± 0.096
1.234TyrGln: 1.234 ± 0.048
1.645TyrArg: 1.645 ± 0.276
2.057TyrSer: 2.057 ± 1.404
1.645TyrThr: 1.645 ± 0.912
5.759TyrVal: 5.759 ± 0.624
0.823TyrTrp: 0.823 ± 0.18
2.057TyrTyr: 2.057 ± 0.504
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2432 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski