Amino acid dipepetide frequency for Rice stripe virus (isolate T) (RSV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.021AlaAla: 2.021 ± 0.665
1.213AlaCys: 1.213 ± 0.865
2.223AlaAsp: 2.223 ± 0.881
3.84AlaGlu: 3.84 ± 0.512
0.606AlaPhe: 0.606 ± 0.309
2.223AlaGly: 2.223 ± 0.903
1.415AlaHis: 1.415 ± 0.82
4.446AlaIle: 4.446 ± 0.679
3.032AlaLys: 3.032 ± 0.728
5.053AlaLeu: 5.053 ± 1.89
1.617AlaMet: 1.617 ± 0.718
1.617AlaAsn: 1.617 ± 0.325
2.223AlaPro: 2.223 ± 0.555
1.415AlaGln: 1.415 ± 0.567
1.617AlaArg: 1.617 ± 0.369
2.425AlaSer: 2.425 ± 0.482
2.425AlaThr: 2.425 ± 1.135
4.446AlaVal: 4.446 ± 0.56
0.808AlaTrp: 0.808 ± 0.256
2.223AlaTyr: 2.223 ± 0.412
0.0AlaXaa: 0.0 ± 0.0
Cys
0.404CysAla: 0.404 ± 0.218
0.404CysCys: 0.404 ± 0.37
1.617CysAsp: 1.617 ± 1.234
1.213CysGlu: 1.213 ± 0.706
0.606CysPhe: 0.606 ± 0.432
0.0CysGly: 0.0 ± 0.0
0.606CysHis: 0.606 ± 0.695
1.213CysIle: 1.213 ± 0.378
1.617CysLys: 1.617 ± 1.28
1.011CysLeu: 1.011 ± 0.326
0.606CysMet: 0.606 ± 0.201
0.202CysAsn: 0.202 ± 0.109
1.011CysPro: 1.011 ± 0.782
1.011CysGln: 1.011 ± 0.382
1.011CysArg: 1.011 ± 0.278
2.021CysSer: 2.021 ± 0.684
1.415CysThr: 1.415 ± 0.573
1.415CysVal: 1.415 ± 0.44
0.404CysTrp: 0.404 ± 0.629
1.011CysTyr: 1.011 ± 0.446
0.0CysXaa: 0.0 ± 0.0
Asp
3.638AspAla: 3.638 ± 0.808
0.404AspCys: 0.404 ± 0.218
3.638AspAsp: 3.638 ± 1.659
4.042AspGlu: 4.042 ± 0.767
2.223AspPhe: 2.223 ± 0.7
2.021AspGly: 2.021 ± 0.72
2.223AspHis: 2.223 ± 1.342
4.042AspIle: 4.042 ± 0.761
4.85AspLys: 4.85 ± 0.713
4.446AspLeu: 4.446 ± 0.441
1.617AspMet: 1.617 ± 1.285
3.84AspAsn: 3.84 ± 1.094
2.829AspPro: 2.829 ± 1.149
3.638AspGln: 3.638 ± 0.924
1.011AspArg: 1.011 ± 0.545
3.638AspSer: 3.638 ± 0.778
3.436AspThr: 3.436 ± 1.992
5.053AspVal: 5.053 ± 0.529
0.404AspTrp: 0.404 ± 0.218
2.829AspTyr: 2.829 ± 0.363
0.0AspXaa: 0.0 ± 0.0
Glu
2.627GluAla: 2.627 ± 0.608
1.617GluCys: 1.617 ± 0.429
5.053GluAsp: 5.053 ± 0.746
6.265GluGlu: 6.265 ± 1.214
3.84GluPhe: 3.84 ± 1.092
2.627GluGly: 2.627 ± 0.886
1.617GluHis: 1.617 ± 0.791
3.638GluIle: 3.638 ± 0.92
4.042GluLys: 4.042 ± 1.422
6.265GluLeu: 6.265 ± 1.76
1.617GluMet: 1.617 ± 0.872
2.829GluAsn: 2.829 ± 0.595
2.021GluPro: 2.021 ± 0.652
1.819GluGln: 1.819 ± 0.981
3.84GluArg: 3.84 ± 0.598
6.265GluSer: 6.265 ± 0.704
5.457GluThr: 5.457 ± 1.482
5.053GluVal: 5.053 ± 0.673
0.202GluTrp: 0.202 ± 0.246
2.021GluTyr: 2.021 ± 0.694
0.0GluXaa: 0.0 ± 0.0
Phe
1.011PheAla: 1.011 ± 0.756
0.606PheCys: 0.606 ± 0.491
2.425PheAsp: 2.425 ± 0.533
2.829PheGlu: 2.829 ± 0.768
2.425PhePhe: 2.425 ± 0.464
1.617PheGly: 1.617 ± 0.485
1.213PheHis: 1.213 ± 0.328
3.638PheIle: 3.638 ± 0.663
4.042PheLys: 4.042 ± 1.28
4.446PheLeu: 4.446 ± 0.844
0.808PheMet: 0.808 ± 0.424
2.829PheAsn: 2.829 ± 1.076
2.223PhePro: 2.223 ± 0.489
0.808PheGln: 0.808 ± 0.438
1.617PheArg: 1.617 ± 0.718
3.638PheSer: 3.638 ± 0.79
2.021PheThr: 2.021 ± 1.245
3.234PheVal: 3.234 ± 1.11
0.606PheTrp: 0.606 ± 0.309
1.011PheTyr: 1.011 ± 0.545
0.0PheXaa: 0.0 ± 0.0
Gly
1.213GlyAla: 1.213 ± 0.511
1.011GlyCys: 1.011 ± 0.976
2.223GlyAsp: 2.223 ± 0.515
2.627GlyGlu: 2.627 ± 0.576
3.84GlyPhe: 3.84 ± 0.979
2.829GlyGly: 2.829 ± 0.83
1.415GlyHis: 1.415 ± 0.447
4.244GlyIle: 4.244 ± 1.117
2.425GlyLys: 2.425 ± 0.566
4.244GlyLeu: 4.244 ± 1.947
1.415GlyMet: 1.415 ± 0.584
1.819GlyAsn: 1.819 ± 0.425
0.808GlyPro: 0.808 ± 0.607
0.606GlyGln: 0.606 ± 0.259
2.425GlyArg: 2.425 ± 0.604
3.638GlySer: 3.638 ± 0.838
2.829GlyThr: 2.829 ± 0.726
2.223GlyVal: 2.223 ± 0.479
0.404GlyTrp: 0.404 ± 0.481
1.213GlyTyr: 1.213 ± 0.378
0.0GlyXaa: 0.0 ± 0.0
His
0.808HisAla: 0.808 ± 0.371
0.606HisCys: 0.606 ± 0.314
1.819HisAsp: 1.819 ± 0.755
1.213HisGlu: 1.213 ± 0.433
0.808HisPhe: 0.808 ± 0.256
1.213HisGly: 1.213 ± 0.301
0.606HisHis: 0.606 ± 0.462
2.425HisIle: 2.425 ± 0.981
2.627HisLys: 2.627 ± 1.323
1.819HisLeu: 1.819 ± 0.621
0.202HisMet: 0.202 ± 0.109
0.808HisAsn: 0.808 ± 0.353
2.223HisPro: 2.223 ± 1.107
1.011HisGln: 1.011 ± 1.014
1.213HisArg: 1.213 ± 0.328
2.021HisSer: 2.021 ± 1.005
0.808HisThr: 0.808 ± 0.371
1.415HisVal: 1.415 ± 0.573
0.202HisTrp: 0.202 ± 0.109
1.819HisTyr: 1.819 ± 0.67
0.0HisXaa: 0.0 ± 0.0
Ile
2.829IleAla: 2.829 ± 0.721
1.415IleCys: 1.415 ± 0.406
2.627IleAsp: 2.627 ± 0.791
6.265IleGlu: 6.265 ± 1.225
2.223IlePhe: 2.223 ± 0.555
2.627IleGly: 2.627 ± 0.479
1.819IleHis: 1.819 ± 0.612
4.042IleIle: 4.042 ± 0.719
5.659IleLys: 5.659 ± 1.203
6.063IleLeu: 6.063 ± 1.21
2.021IleMet: 2.021 ± 0.502
3.638IleAsn: 3.638 ± 0.778
3.234IlePro: 3.234 ± 0.511
3.234IleGln: 3.234 ± 0.728
2.223IleArg: 2.223 ± 0.775
7.276IleSer: 7.276 ± 0.951
5.457IleThr: 5.457 ± 1.834
4.042IleVal: 4.042 ± 0.861
1.213IleTrp: 1.213 ± 0.469
2.829IleTyr: 2.829 ± 0.684
0.0IleXaa: 0.0 ± 0.0
Lys
3.84LysAla: 3.84 ± 1.09
1.617LysCys: 1.617 ± 0.861
4.648LysAsp: 4.648 ± 1.164
7.074LysGlu: 7.074 ± 1.662
3.84LysPhe: 3.84 ± 0.861
3.436LysGly: 3.436 ± 0.313
1.819LysHis: 1.819 ± 0.621
4.446LysIle: 4.446 ± 1.037
7.68LysLys: 7.68 ± 1.426
6.467LysLeu: 6.467 ± 1.182
2.425LysMet: 2.425 ± 1.434
4.244LysAsn: 4.244 ± 0.514
3.234LysPro: 3.234 ± 1.235
1.617LysGln: 1.617 ± 0.707
3.234LysArg: 3.234 ± 0.526
5.457LysSer: 5.457 ± 1.758
6.467LysThr: 6.467 ± 0.616
5.457LysVal: 5.457 ± 1.007
0.606LysTrp: 0.606 ± 0.327
2.021LysTyr: 2.021 ± 1.126
0.0LysXaa: 0.0 ± 0.0
Leu
6.467LeuAla: 6.467 ± 1.324
1.213LeuCys: 1.213 ± 0.469
4.85LeuAsp: 4.85 ± 0.739
5.457LeuGlu: 5.457 ± 1.05
3.84LeuPhe: 3.84 ± 1.014
5.861LeuGly: 5.861 ± 0.717
1.819LeuHis: 1.819 ± 0.602
5.457LeuIle: 5.457 ± 0.65
8.892LeuLys: 8.892 ± 1.112
9.701LeuLeu: 9.701 ± 1.524
3.234LeuMet: 3.234 ± 0.671
4.244LeuAsn: 4.244 ± 0.907
3.638LeuPro: 3.638 ± 2.034
2.223LeuGln: 2.223 ± 0.395
4.648LeuArg: 4.648 ± 1.18
9.903LeuSer: 9.903 ± 0.857
3.234LeuThr: 3.234 ± 0.595
5.053LeuVal: 5.053 ± 1.469
1.617LeuTrp: 1.617 ± 0.547
4.446LeuTyr: 4.446 ± 0.458
0.0LeuXaa: 0.0 ± 0.0
Met
1.617MetAla: 1.617 ± 0.697
0.808MetCys: 0.808 ± 0.487
1.415MetAsp: 1.415 ± 0.447
2.021MetGlu: 2.021 ± 0.596
1.213MetPhe: 1.213 ± 0.589
1.011MetGly: 1.011 ± 0.422
0.404MetHis: 0.404 ± 0.196
2.627MetIle: 2.627 ± 0.842
3.436MetLys: 3.436 ± 0.792
2.829MetLeu: 2.829 ± 0.922
1.213MetMet: 1.213 ± 0.577
1.011MetAsn: 1.011 ± 0.278
1.011MetPro: 1.011 ± 0.524
0.808MetGln: 0.808 ± 0.468
0.808MetArg: 0.808 ± 0.487
1.819MetSer: 1.819 ± 0.814
1.213MetThr: 1.213 ± 0.487
1.011MetVal: 1.011 ± 0.283
0.202MetTrp: 0.202 ± 0.109
0.606MetTyr: 0.606 ± 0.327
0.0MetXaa: 0.0 ± 0.0
Asn
2.021AsnAla: 2.021 ± 0.744
1.011AsnCys: 1.011 ± 0.689
2.627AsnAsp: 2.627 ± 0.438
1.819AsnGlu: 1.819 ± 0.508
2.425AsnPhe: 2.425 ± 0.954
3.032AsnGly: 3.032 ± 1.016
0.606AsnHis: 0.606 ± 0.309
3.234AsnIle: 3.234 ± 0.511
3.234AsnLys: 3.234 ± 0.968
4.446AsnLeu: 4.446 ± 1.144
1.819AsnMet: 1.819 ± 0.535
2.021AsnAsn: 2.021 ± 0.653
1.617AsnPro: 1.617 ± 0.485
2.425AsnGln: 2.425 ± 0.932
2.425AsnArg: 2.425 ± 0.416
2.829AsnSer: 2.829 ± 1.391
2.223AsnThr: 2.223 ± 0.526
3.032AsnVal: 3.032 ± 0.54
1.213AsnTrp: 1.213 ± 0.401
2.021AsnTyr: 2.021 ± 0.764
0.0AsnXaa: 0.0 ± 0.0
Pro
2.829ProAla: 2.829 ± 0.421
0.404ProCys: 0.404 ± 0.493
2.425ProAsp: 2.425 ± 0.802
3.032ProGlu: 3.032 ± 1.402
1.617ProPhe: 1.617 ± 0.53
1.011ProGly: 1.011 ± 0.278
0.404ProHis: 0.404 ± 0.37
3.032ProIle: 3.032 ± 0.941
1.819ProLys: 1.819 ± 0.578
4.648ProLeu: 4.648 ± 1.312
0.606ProMet: 0.606 ± 0.201
1.819ProAsn: 1.819 ± 0.518
1.011ProPro: 1.011 ± 1.012
0.808ProGln: 0.808 ± 0.249
1.213ProArg: 1.213 ± 0.301
4.648ProSer: 4.648 ± 1.919
2.829ProThr: 2.829 ± 0.841
1.819ProVal: 1.819 ± 0.552
0.202ProTrp: 0.202 ± 0.109
1.011ProTyr: 1.011 ± 0.318
0.0ProXaa: 0.0 ± 0.0
Gln
1.819GlnAla: 1.819 ± 0.578
0.606GlnCys: 0.606 ± 0.432
2.627GlnAsp: 2.627 ± 0.527
2.627GlnGlu: 2.627 ± 1.416
1.415GlnPhe: 1.415 ± 0.432
1.011GlnGly: 1.011 ± 0.432
0.202GlnHis: 0.202 ± 0.109
2.021GlnIle: 2.021 ± 1.219
2.627GlnLys: 2.627 ± 0.551
3.234GlnLeu: 3.234 ± 1.532
0.808GlnMet: 0.808 ± 0.436
1.213GlnAsn: 1.213 ± 0.395
1.213GlnPro: 1.213 ± 1.199
0.808GlnGln: 0.808 ± 0.518
1.213GlnArg: 1.213 ± 0.55
1.415GlnSer: 1.415 ± 0.584
1.819GlnThr: 1.819 ± 0.385
2.021GlnVal: 2.021 ± 0.653
0.0GlnTrp: 0.0 ± 0.0
1.415GlnTyr: 1.415 ± 0.47
0.0GlnXaa: 0.0 ± 0.0
Arg
3.032ArgAla: 3.032 ± 0.874
0.808ArgCys: 0.808 ± 0.358
2.223ArgAsp: 2.223 ± 0.744
3.436ArgGlu: 3.436 ± 1.1
0.404ArgPhe: 0.404 ± 0.196
1.415ArgGly: 1.415 ± 0.567
1.213ArgHis: 1.213 ± 1.069
3.436ArgIle: 3.436 ± 1.181
3.234ArgLys: 3.234 ± 0.476
4.042ArgLeu: 4.042 ± 1.082
1.617ArgMet: 1.617 ± 0.513
1.819ArgAsn: 1.819 ± 0.741
1.213ArgPro: 1.213 ± 0.335
0.404ArgGln: 0.404 ± 0.368
1.819ArgArg: 1.819 ± 0.741
5.053ArgSer: 5.053 ± 2.203
2.425ArgThr: 2.425 ± 0.561
3.032ArgVal: 3.032 ± 0.779
0.606ArgTrp: 0.606 ± 0.327
2.223ArgTyr: 2.223 ± 0.484
0.0ArgXaa: 0.0 ± 0.0
Ser
4.244SerAla: 4.244 ± 0.996
1.617SerCys: 1.617 ± 1.351
5.659SerAsp: 5.659 ± 1.063
3.638SerGlu: 3.638 ± 0.527
4.446SerPhe: 4.446 ± 1.121
3.032SerGly: 3.032 ± 0.441
2.021SerHis: 2.021 ± 0.892
6.265SerIle: 6.265 ± 1.332
6.669SerLys: 6.669 ± 1.571
9.095SerLeu: 9.095 ± 1.132
1.415SerMet: 1.415 ± 0.388
3.436SerAsn: 3.436 ± 1.008
2.829SerPro: 2.829 ± 0.807
2.627SerGln: 2.627 ± 1.24
4.244SerArg: 4.244 ± 0.822
7.882SerSer: 7.882 ± 2.302
4.446SerThr: 4.446 ± 0.915
6.467SerVal: 6.467 ± 1.29
1.011SerTrp: 1.011 ± 0.339
3.84SerTyr: 3.84 ± 0.572
0.0SerXaa: 0.0 ± 0.0
Thr
2.021ThrAla: 2.021 ± 0.683
1.213ThrCys: 1.213 ± 0.787
3.234ThrAsp: 3.234 ± 0.511
4.244ThrGlu: 4.244 ± 1.475
2.021ThrPhe: 2.021 ± 0.521
2.829ThrGly: 2.829 ± 1.011
1.415ThrHis: 1.415 ± 0.397
4.446ThrIle: 4.446 ± 0.517
3.638ThrLys: 3.638 ± 0.965
8.286ThrLeu: 8.286 ± 1.957
2.021ThrMet: 2.021 ± 0.833
3.234ThrAsn: 3.234 ± 1.404
2.021ThrPro: 2.021 ± 0.846
1.617ThrGln: 1.617 ± 0.652
2.627ThrArg: 2.627 ± 0.952
4.042ThrSer: 4.042 ± 1.791
5.255ThrThr: 5.255 ± 1.027
3.032ThrVal: 3.032 ± 0.557
0.404ThrTrp: 0.404 ± 0.218
2.627ThrTyr: 2.627 ± 0.465
0.0ThrXaa: 0.0 ± 0.0
Val
2.425ValAla: 2.425 ± 0.657
1.213ValCys: 1.213 ± 0.589
4.85ValAsp: 4.85 ± 0.824
4.244ValGlu: 4.244 ± 0.883
2.829ValPhe: 2.829 ± 1.025
3.234ValGly: 3.234 ± 1.193
2.021ValHis: 2.021 ± 0.664
4.446ValIle: 4.446 ± 0.593
6.063ValLys: 6.063 ± 1.773
4.244ValLeu: 4.244 ± 0.896
0.606ValMet: 0.606 ± 0.309
3.436ValAsn: 3.436 ± 0.665
1.415ValPro: 1.415 ± 0.762
2.223ValGln: 2.223 ± 0.824
3.436ValArg: 3.436 ± 0.759
8.084ValSer: 8.084 ± 1.463
3.436ValThr: 3.436 ± 0.633
4.446ValVal: 4.446 ± 0.652
1.011ValTrp: 1.011 ± 0.53
3.032ValTyr: 3.032 ± 0.686
0.0ValXaa: 0.0 ± 0.0
Trp
0.202TrpAla: 0.202 ± 0.109
0.202TrpCys: 0.202 ± 0.109
0.606TrpAsp: 0.606 ± 0.259
0.202TrpGlu: 0.202 ± 0.109
1.011TrpPhe: 1.011 ± 0.553
0.808TrpGly: 0.808 ± 0.49
0.404TrpHis: 0.404 ± 0.218
1.415TrpIle: 1.415 ± 0.627
0.808TrpLys: 0.808 ± 0.611
1.213TrpLeu: 1.213 ± 0.701
0.808TrpMet: 0.808 ± 0.393
0.606TrpAsn: 0.606 ± 0.327
0.606TrpPro: 0.606 ± 0.327
0.202TrpGln: 0.202 ± 0.109
0.808TrpArg: 0.808 ± 0.436
0.606TrpSer: 0.606 ± 0.327
0.404TrpThr: 0.404 ± 0.314
0.606TrpVal: 0.606 ± 0.327
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.819TyrAla: 1.819 ± 0.425
0.808TyrCys: 0.808 ± 0.487
3.032TyrAsp: 3.032 ± 1.047
2.627TyrGlu: 2.627 ± 0.576
1.415TyrPhe: 1.415 ± 0.64
1.617TyrGly: 1.617 ± 0.594
2.425TyrHis: 2.425 ± 0.586
2.223TyrIle: 2.223 ± 0.913
3.234TyrLys: 3.234 ± 0.859
4.244TyrLeu: 4.244 ± 0.793
0.606TyrMet: 0.606 ± 0.327
1.415TyrAsn: 1.415 ± 0.573
0.808TyrPro: 0.808 ± 0.537
0.808TyrGln: 0.808 ± 0.256
2.021TyrArg: 2.021 ± 0.622
2.223TyrSer: 2.223 ± 1.239
2.627TyrThr: 2.627 ± 0.626
3.84TyrVal: 3.84 ± 1.287
0.404TyrTrp: 0.404 ± 0.269
2.021TyrTyr: 2.021 ± 0.782
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (4949 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski