Amino acid dipepetide frequency for Xanthomonas phage f30-Xaj

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
14.75AlaAla: 14.75 ± 1.872
0.382AlaCys: 0.382 ± 0.159
6.114AlaAsp: 6.114 ± 0.74
6.572AlaGlu: 6.572 ± 0.856
3.363AlaPhe: 3.363 ± 0.458
7.795AlaGly: 7.795 ± 1.271
1.834AlaHis: 1.834 ± 0.421
5.044AlaIle: 5.044 ± 0.6
6.037AlaLys: 6.037 ± 0.66
8.101AlaLeu: 8.101 ± 0.703
4.05AlaMet: 4.05 ± 0.631
3.592AlaAsn: 3.592 ± 0.648
4.585AlaPro: 4.585 ± 1.038
5.579AlaGln: 5.579 ± 0.61
5.502AlaArg: 5.502 ± 0.592
5.961AlaSer: 5.961 ± 0.548
6.19AlaThr: 6.19 ± 0.803
6.649AlaVal: 6.649 ± 0.81
2.063AlaTrp: 2.063 ± 0.459
2.751AlaTyr: 2.751 ± 0.597
0.0AlaXaa: 0.0 ± 0.0
Cys
0.535CysAla: 0.535 ± 0.212
0.0CysCys: 0.0 ± 0.0
0.535CysAsp: 0.535 ± 0.228
0.459CysGlu: 0.459 ± 0.204
0.382CysPhe: 0.382 ± 0.203
0.535CysGly: 0.535 ± 0.255
0.076CysHis: 0.076 ± 0.068
0.459CysIle: 0.459 ± 0.191
0.382CysLys: 0.382 ± 0.203
0.688CysLeu: 0.688 ± 0.213
0.153CysMet: 0.153 ± 0.13
0.688CysAsn: 0.688 ± 0.21
0.153CysPro: 0.153 ± 0.134
0.535CysGln: 0.535 ± 0.272
0.459CysArg: 0.459 ± 0.222
0.229CysSer: 0.229 ± 0.146
0.764CysThr: 0.764 ± 0.302
0.229CysVal: 0.229 ± 0.123
0.076CysTrp: 0.076 ± 0.095
0.306CysTyr: 0.306 ± 0.178
0.0CysXaa: 0.0 ± 0.0
Asp
6.802AspAla: 6.802 ± 0.642
0.459AspCys: 0.459 ± 0.213
3.974AspAsp: 3.974 ± 0.615
3.286AspGlu: 3.286 ± 0.452
3.286AspPhe: 3.286 ± 0.463
5.044AspGly: 5.044 ± 0.661
0.841AspHis: 0.841 ± 0.323
3.286AspIle: 3.286 ± 0.397
3.515AspLys: 3.515 ± 0.495
4.28AspLeu: 4.28 ± 0.601
1.528AspMet: 1.528 ± 0.359
2.904AspAsn: 2.904 ± 0.47
2.446AspPro: 2.446 ± 0.414
2.522AspGln: 2.522 ± 0.504
3.668AspArg: 3.668 ± 0.53
3.821AspSer: 3.821 ± 0.65
2.904AspThr: 2.904 ± 0.475
4.203AspVal: 4.203 ± 0.612
0.994AspTrp: 0.994 ± 0.242
1.758AspTyr: 1.758 ± 0.423
0.0AspXaa: 0.0 ± 0.0
Glu
6.037GluAla: 6.037 ± 0.686
0.306GluCys: 0.306 ± 0.154
3.21GluAsp: 3.21 ± 0.428
4.127GluGlu: 4.127 ± 0.573
2.522GluPhe: 2.522 ± 0.421
4.356GluGly: 4.356 ± 0.428
1.758GluHis: 1.758 ± 0.374
2.14GluIle: 2.14 ± 0.446
2.904GluLys: 2.904 ± 0.55
6.725GluLeu: 6.725 ± 0.677
1.605GluMet: 1.605 ± 0.277
2.675GluAsn: 2.675 ± 0.556
1.834GluPro: 1.834 ± 0.394
2.904GluGln: 2.904 ± 0.49
2.904GluArg: 2.904 ± 0.483
2.522GluSer: 2.522 ± 0.452
2.828GluThr: 2.828 ± 0.314
3.363GluVal: 3.363 ± 0.489
1.605GluTrp: 1.605 ± 0.396
2.598GluTyr: 2.598 ± 0.491
0.0GluXaa: 0.0 ± 0.0
Phe
3.286PheAla: 3.286 ± 0.489
0.382PheCys: 0.382 ± 0.154
2.751PheAsp: 2.751 ± 0.466
1.299PheGlu: 1.299 ± 0.311
0.841PhePhe: 0.841 ± 0.275
3.286PheGly: 3.286 ± 0.469
0.994PheHis: 0.994 ± 0.243
1.452PheIle: 1.452 ± 0.372
1.299PheLys: 1.299 ± 0.385
2.598PheLeu: 2.598 ± 0.409
0.688PheMet: 0.688 ± 0.212
1.528PheAsn: 1.528 ± 0.425
1.299PhePro: 1.299 ± 0.365
1.452PheGln: 1.452 ± 0.27
1.834PheArg: 1.834 ± 0.345
2.675PheSer: 2.675 ± 0.437
1.605PheThr: 1.605 ± 0.345
2.522PheVal: 2.522 ± 0.677
0.153PheTrp: 0.153 ± 0.091
1.605PheTyr: 1.605 ± 0.38
0.0PheXaa: 0.0 ± 0.0
Gly
8.024GlyAla: 8.024 ± 1.021
0.688GlyCys: 0.688 ± 0.275
5.35GlyAsp: 5.35 ± 0.655
4.662GlyGlu: 4.662 ± 0.592
2.598GlyPhe: 2.598 ± 0.352
7.566GlyGly: 7.566 ± 0.961
1.299GlyHis: 1.299 ± 0.425
3.821GlyIle: 3.821 ± 0.591
4.968GlyLys: 4.968 ± 0.646
5.732GlyLeu: 5.732 ± 0.548
2.904GlyMet: 2.904 ± 0.477
3.974GlyAsn: 3.974 ± 0.466
2.446GlyPro: 2.446 ± 0.474
3.592GlyGln: 3.592 ± 0.547
4.815GlyArg: 4.815 ± 0.703
5.579GlySer: 5.579 ± 0.86
5.273GlyThr: 5.273 ± 0.683
5.502GlyVal: 5.502 ± 0.618
1.376GlyTrp: 1.376 ± 0.356
2.751GlyTyr: 2.751 ± 0.427
0.0GlyXaa: 0.0 ± 0.0
His
1.758HisAla: 1.758 ± 0.368
0.153HisCys: 0.153 ± 0.121
1.758HisAsp: 1.758 ± 0.378
1.299HisGlu: 1.299 ± 0.251
0.459HisPhe: 0.459 ± 0.208
1.452HisGly: 1.452 ± 0.346
0.688HisHis: 0.688 ± 0.251
1.146HisIle: 1.146 ± 0.246
1.223HisLys: 1.223 ± 0.478
0.994HisLeu: 0.994 ± 0.302
0.459HisMet: 0.459 ± 0.175
0.994HisAsn: 0.994 ± 0.326
1.146HisPro: 1.146 ± 0.342
0.535HisGln: 0.535 ± 0.267
1.376HisArg: 1.376 ± 0.358
1.146HisSer: 1.146 ± 0.28
1.07HisThr: 1.07 ± 0.308
1.223HisVal: 1.223 ± 0.388
0.535HisTrp: 0.535 ± 0.178
1.07HisTyr: 1.07 ± 0.356
0.0HisXaa: 0.0 ± 0.0
Ile
5.12IleAla: 5.12 ± 0.696
0.382IleCys: 0.382 ± 0.171
3.133IleAsp: 3.133 ± 0.436
3.439IleGlu: 3.439 ± 0.466
1.452IlePhe: 1.452 ± 0.408
3.286IleGly: 3.286 ± 0.501
1.223IleHis: 1.223 ± 0.409
1.758IleIle: 1.758 ± 0.377
2.293IleLys: 2.293 ± 0.485
2.981IleLeu: 2.981 ± 0.383
1.07IleMet: 1.07 ± 0.203
3.21IleAsn: 3.21 ± 0.509
2.522IlePro: 2.522 ± 0.384
1.681IleGln: 1.681 ± 0.277
2.828IleArg: 2.828 ± 0.347
1.528IleSer: 1.528 ± 0.331
2.904IleThr: 2.904 ± 0.459
2.751IleVal: 2.751 ± 0.435
0.306IleTrp: 0.306 ± 0.146
0.841IleTyr: 0.841 ± 0.207
0.0IleXaa: 0.0 ± 0.0
Lys
5.808LysAla: 5.808 ± 0.71
0.153LysCys: 0.153 ± 0.118
3.515LysAsp: 3.515 ± 0.563
2.828LysGlu: 2.828 ± 0.568
1.987LysPhe: 1.987 ± 0.32
3.515LysGly: 3.515 ± 0.636
1.299LysHis: 1.299 ± 0.298
2.216LysIle: 2.216 ± 0.396
1.452LysLys: 1.452 ± 0.47
4.891LysLeu: 4.891 ± 0.759
1.223LysMet: 1.223 ± 0.293
1.758LysAsn: 1.758 ± 0.299
2.446LysPro: 2.446 ± 0.499
2.216LysGln: 2.216 ± 0.438
4.127LysArg: 4.127 ± 0.813
2.14LysSer: 2.14 ± 0.389
2.369LysThr: 2.369 ± 0.329
2.981LysVal: 2.981 ± 0.624
1.07LysTrp: 1.07 ± 0.249
2.446LysTyr: 2.446 ± 0.4
0.0LysXaa: 0.0 ± 0.0
Leu
7.719LeuAla: 7.719 ± 0.979
1.146LeuCys: 1.146 ± 0.376
5.426LeuAsp: 5.426 ± 0.459
5.502LeuGlu: 5.502 ± 0.704
1.299LeuPhe: 1.299 ± 0.302
5.885LeuGly: 5.885 ± 0.561
1.911LeuHis: 1.911 ± 0.463
3.286LeuIle: 3.286 ± 0.558
4.203LeuLys: 4.203 ± 0.641
7.107LeuLeu: 7.107 ± 0.791
1.758LeuMet: 1.758 ± 0.276
3.363LeuAsn: 3.363 ± 0.488
3.745LeuPro: 3.745 ± 0.586
3.363LeuGln: 3.363 ± 0.629
6.037LeuArg: 6.037 ± 0.617
5.044LeuSer: 5.044 ± 0.616
5.35LeuThr: 5.35 ± 0.473
5.273LeuVal: 5.273 ± 0.748
1.07LeuTrp: 1.07 ± 0.272
2.522LeuTyr: 2.522 ± 0.48
0.0LeuXaa: 0.0 ± 0.0
Met
2.675MetAla: 2.675 ± 0.445
0.0MetCys: 0.0 ± 0.0
2.446MetAsp: 2.446 ± 0.422
1.681MetGlu: 1.681 ± 0.431
0.841MetPhe: 0.841 ± 0.222
2.14MetGly: 2.14 ± 0.442
0.459MetHis: 0.459 ± 0.166
0.917MetIle: 0.917 ± 0.274
1.146MetLys: 1.146 ± 0.362
2.522MetLeu: 2.522 ± 0.364
0.535MetMet: 0.535 ± 0.22
0.688MetAsn: 0.688 ± 0.202
0.841MetPro: 0.841 ± 0.253
1.452MetGln: 1.452 ± 0.339
2.369MetArg: 2.369 ± 0.639
2.522MetSer: 2.522 ± 0.359
1.681MetThr: 1.681 ± 0.324
1.605MetVal: 1.605 ± 0.357
0.229MetTrp: 0.229 ± 0.126
0.841MetTyr: 0.841 ± 0.282
0.0MetXaa: 0.0 ± 0.0
Asn
4.509AsnAla: 4.509 ± 0.614
0.382AsnCys: 0.382 ± 0.167
2.446AsnAsp: 2.446 ± 0.399
2.293AsnGlu: 2.293 ± 0.36
1.299AsnPhe: 1.299 ± 0.331
4.509AsnGly: 4.509 ± 0.577
0.917AsnHis: 0.917 ± 0.237
1.987AsnIle: 1.987 ± 0.375
2.369AsnLys: 2.369 ± 0.472
2.598AsnLeu: 2.598 ± 0.399
1.452AsnMet: 1.452 ± 0.313
1.528AsnAsn: 1.528 ± 0.388
2.216AsnPro: 2.216 ± 0.363
1.911AsnGln: 1.911 ± 0.404
2.522AsnArg: 2.522 ± 0.468
2.598AsnSer: 2.598 ± 0.451
3.057AsnThr: 3.057 ± 0.683
2.216AsnVal: 2.216 ± 0.457
0.841AsnTrp: 0.841 ± 0.252
1.223AsnTyr: 1.223 ± 0.283
0.0AsnXaa: 0.0 ± 0.0
Pro
4.28ProAla: 4.28 ± 1.151
0.382ProCys: 0.382 ± 0.177
2.598ProAsp: 2.598 ± 0.429
2.598ProGlu: 2.598 ± 0.403
1.223ProPhe: 1.223 ± 0.353
3.057ProGly: 3.057 ± 0.632
0.688ProHis: 0.688 ± 0.289
1.223ProIle: 1.223 ± 0.359
2.14ProLys: 2.14 ± 0.44
3.363ProLeu: 3.363 ± 0.436
1.299ProMet: 1.299 ± 0.284
2.063ProAsn: 2.063 ± 0.333
1.605ProPro: 1.605 ± 0.493
1.146ProGln: 1.146 ± 0.245
1.376ProArg: 1.376 ± 0.268
2.598ProSer: 2.598 ± 0.446
3.439ProThr: 3.439 ± 0.622
3.592ProVal: 3.592 ± 0.761
0.764ProTrp: 0.764 ± 0.219
0.917ProTyr: 0.917 ± 0.287
0.0ProXaa: 0.0 ± 0.0
Gln
5.808GlnAla: 5.808 ± 0.891
0.306GlnCys: 0.306 ± 0.171
1.834GlnAsp: 1.834 ± 0.368
2.522GlnGlu: 2.522 ± 0.513
1.987GlnPhe: 1.987 ± 0.321
4.127GlnGly: 4.127 ± 0.565
0.611GlnHis: 0.611 ± 0.19
1.987GlnIle: 1.987 ± 0.368
1.834GlnLys: 1.834 ± 0.362
3.668GlnLeu: 3.668 ± 0.525
1.146GlnMet: 1.146 ± 0.267
1.376GlnAsn: 1.376 ± 0.292
1.376GlnPro: 1.376 ± 0.456
2.751GlnGln: 2.751 ± 0.567
3.21GlnArg: 3.21 ± 0.652
2.522GlnSer: 2.522 ± 0.515
3.21GlnThr: 3.21 ± 0.659
2.293GlnVal: 2.293 ± 0.413
0.841GlnTrp: 0.841 ± 0.226
1.299GlnTyr: 1.299 ± 0.31
0.0GlnXaa: 0.0 ± 0.0
Arg
5.885ArgAla: 5.885 ± 0.767
0.611ArgCys: 0.611 ± 0.237
3.21ArgAsp: 3.21 ± 0.435
3.363ArgGlu: 3.363 ± 0.674
2.063ArgPhe: 2.063 ± 0.411
4.433ArgGly: 4.433 ± 0.618
1.376ArgHis: 1.376 ± 0.226
3.439ArgIle: 3.439 ± 0.614
4.738ArgLys: 4.738 ± 0.669
4.662ArgLeu: 4.662 ± 0.693
2.14ArgMet: 2.14 ± 0.391
2.751ArgAsn: 2.751 ± 0.382
2.063ArgPro: 2.063 ± 0.414
2.598ArgGln: 2.598 ± 0.392
3.21ArgArg: 3.21 ± 0.59
3.133ArgSer: 3.133 ± 0.426
2.675ArgThr: 2.675 ± 0.491
4.662ArgVal: 4.662 ± 0.5
0.841ArgTrp: 0.841 ± 0.252
2.522ArgTyr: 2.522 ± 0.456
0.0ArgXaa: 0.0 ± 0.0
Ser
6.19SerAla: 6.19 ± 0.669
0.459SerCys: 0.459 ± 0.22
3.21SerAsp: 3.21 ± 0.492
3.133SerGlu: 3.133 ± 0.358
1.911SerPhe: 1.911 ± 0.468
6.267SerGly: 6.267 ± 0.804
0.764SerHis: 0.764 ± 0.291
2.904SerIle: 2.904 ± 0.423
2.063SerLys: 2.063 ± 0.417
4.815SerLeu: 4.815 ± 0.523
1.528SerMet: 1.528 ± 0.234
2.751SerAsn: 2.751 ± 0.469
2.293SerPro: 2.293 ± 0.357
2.063SerGln: 2.063 ± 0.376
3.515SerArg: 3.515 ± 0.556
3.133SerSer: 3.133 ± 0.55
4.127SerThr: 4.127 ± 0.538
4.127SerVal: 4.127 ± 0.661
1.299SerTrp: 1.299 ± 0.329
1.528SerTyr: 1.528 ± 0.477
0.0SerXaa: 0.0 ± 0.0
Thr
7.413ThrAla: 7.413 ± 0.848
0.306ThrCys: 0.306 ± 0.192
2.751ThrAsp: 2.751 ± 0.444
3.286ThrGlu: 3.286 ± 0.565
1.911ThrPhe: 1.911 ± 0.37
6.343ThrGly: 6.343 ± 0.64
0.917ThrHis: 0.917 ± 0.214
2.751ThrIle: 2.751 ± 0.419
2.904ThrLys: 2.904 ± 0.608
4.815ThrLeu: 4.815 ± 0.552
0.917ThrMet: 0.917 ± 0.302
2.14ThrAsn: 2.14 ± 0.332
2.598ThrPro: 2.598 ± 0.432
3.363ThrGln: 3.363 ± 0.538
3.133ThrArg: 3.133 ± 0.437
4.05ThrSer: 4.05 ± 0.693
4.28ThrThr: 4.28 ± 0.748
4.356ThrVal: 4.356 ± 0.691
0.841ThrTrp: 0.841 ± 0.273
2.446ThrTyr: 2.446 ± 0.479
0.0ThrXaa: 0.0 ± 0.0
Val
5.961ValAla: 5.961 ± 0.694
0.459ValCys: 0.459 ± 0.184
3.821ValAsp: 3.821 ± 0.663
3.515ValGlu: 3.515 ± 0.477
1.834ValPhe: 1.834 ± 0.347
5.655ValGly: 5.655 ± 0.634
1.758ValHis: 1.758 ± 0.36
2.522ValIle: 2.522 ± 0.401
2.904ValLys: 2.904 ± 0.398
6.267ValLeu: 6.267 ± 0.799
1.987ValMet: 1.987 ± 0.397
2.522ValAsn: 2.522 ± 0.666
3.286ValPro: 3.286 ± 0.421
2.598ValGln: 2.598 ± 0.465
4.127ValArg: 4.127 ± 0.585
4.509ValSer: 4.509 ± 0.617
4.356ValThr: 4.356 ± 0.606
4.509ValVal: 4.509 ± 0.673
1.223ValTrp: 1.223 ± 0.295
2.216ValTyr: 2.216 ± 0.462
0.0ValXaa: 0.0 ± 0.0
Trp
1.299TrpAla: 1.299 ± 0.309
0.459TrpCys: 0.459 ± 0.193
0.764TrpAsp: 0.764 ± 0.263
0.917TrpGlu: 0.917 ± 0.261
0.994TrpPhe: 0.994 ± 0.226
0.764TrpGly: 0.764 ± 0.191
0.611TrpHis: 0.611 ± 0.213
0.917TrpIle: 0.917 ± 0.286
0.994TrpLys: 0.994 ± 0.244
1.758TrpLeu: 1.758 ± 0.362
0.535TrpMet: 0.535 ± 0.194
0.764TrpAsn: 0.764 ± 0.309
0.382TrpPro: 0.382 ± 0.179
0.917TrpGln: 0.917 ± 0.239
0.841TrpArg: 0.841 ± 0.191
0.917TrpSer: 0.917 ± 0.288
0.688TrpThr: 0.688 ± 0.228
1.376TrpVal: 1.376 ± 0.274
0.229TrpTrp: 0.229 ± 0.119
0.841TrpTyr: 0.841 ± 0.253
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.057TyrAla: 3.057 ± 0.564
0.229TyrCys: 0.229 ± 0.137
2.675TyrAsp: 2.675 ± 0.452
2.14TyrGlu: 2.14 ± 0.426
1.299TyrPhe: 1.299 ± 0.309
2.981TyrGly: 2.981 ± 0.429
0.459TyrHis: 0.459 ± 0.208
1.452TyrIle: 1.452 ± 0.407
1.07TyrLys: 1.07 ± 0.304
2.446TyrLeu: 2.446 ± 0.432
0.535TyrMet: 0.535 ± 0.244
1.605TyrAsn: 1.605 ± 0.38
1.07TyrPro: 1.07 ± 0.278
1.528TyrGln: 1.528 ± 0.438
2.522TyrArg: 2.522 ± 0.41
1.452TyrSer: 1.452 ± 0.318
2.751TyrThr: 2.751 ± 0.682
2.598TyrVal: 2.598 ± 0.49
0.611TyrTrp: 0.611 ± 0.264
0.917TyrTyr: 0.917 ± 0.263
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 53 proteins (13086 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski