Amino acid dipepetide frequency for Hubei sobemo-like virus 22

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.263AlaAla: 6.263 ± 0.497
0.0AlaCys: 0.0 ± 0.0
4.175AlaAsp: 4.175 ± 2.359
3.132AlaGlu: 3.132 ± 1.366
1.044AlaPhe: 1.044 ± 0.993
11.482AlaGly: 11.482 ± 1.987
3.132AlaHis: 3.132 ± 1.863
3.132AlaIle: 3.132 ± 0.249
4.175AlaLys: 4.175 ± 0.869
3.132AlaLeu: 3.132 ± 0.249
2.088AlaMet: 2.088 ± 0.372
1.044AlaAsn: 1.044 ± 0.993
6.263AlaPro: 6.263 ± 2.111
1.044AlaGln: 1.044 ± 0.621
5.219AlaArg: 5.219 ± 1.49
3.132AlaSer: 3.132 ± 0.249
4.175AlaThr: 4.175 ± 0.869
12.526AlaVal: 12.526 ± 5.836
3.132AlaTrp: 3.132 ± 0.249
4.175AlaTyr: 4.175 ± 0.745
0.0AlaXaa: 0.0 ± 0.0
Cys
2.088CysAla: 2.088 ± 1.242
0.0CysCys: 0.0 ± 0.0
2.088CysAsp: 2.088 ± 1.242
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
3.132CysGly: 3.132 ± 1.863
0.0CysHis: 0.0 ± 0.0
1.044CysIle: 1.044 ± 0.621
0.0CysLys: 0.0 ± 0.0
1.044CysLeu: 1.044 ± 0.993
1.044CysMet: 1.044 ± 0.621
1.044CysAsn: 1.044 ± 0.993
1.044CysPro: 1.044 ± 0.621
0.0CysGln: 0.0 ± 0.0
2.088CysArg: 2.088 ± 0.372
2.088CysSer: 2.088 ± 0.372
0.0CysThr: 0.0 ± 0.0
2.088CysVal: 2.088 ± 0.372
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
6.263AspAla: 6.263 ± 0.497
1.044AspCys: 1.044 ± 0.621
4.175AspAsp: 4.175 ± 0.745
1.044AspGlu: 1.044 ± 0.621
2.088AspPhe: 2.088 ± 0.372
3.132AspGly: 3.132 ± 1.366
1.044AspHis: 1.044 ± 0.993
2.088AspIle: 2.088 ± 0.372
1.044AspLys: 1.044 ± 0.993
3.132AspLeu: 3.132 ± 1.366
0.0AspMet: 0.0 ± 0.0
2.088AspAsn: 2.088 ± 1.986
3.132AspPro: 3.132 ± 1.366
3.132AspGln: 3.132 ± 1.366
3.132AspArg: 3.132 ± 1.863
3.132AspSer: 3.132 ± 1.863
2.088AspThr: 2.088 ± 1.986
1.044AspVal: 1.044 ± 0.621
3.132AspTrp: 3.132 ± 2.98
1.044AspTyr: 1.044 ± 0.621
0.0AspXaa: 0.0 ± 0.0
Glu
4.175GluAla: 4.175 ± 2.484
1.044GluCys: 1.044 ± 0.993
0.0GluAsp: 0.0 ± 0.0
5.219GluGlu: 5.219 ± 1.49
3.132GluPhe: 3.132 ± 0.249
3.132GluGly: 3.132 ± 0.249
2.088GluHis: 2.088 ± 1.986
2.088GluIle: 2.088 ± 1.242
2.088GluLys: 2.088 ± 1.242
5.219GluLeu: 5.219 ± 1.738
1.044GluMet: 1.044 ± 0.621
1.044GluAsn: 1.044 ± 0.621
4.175GluPro: 4.175 ± 3.973
2.088GluGln: 2.088 ± 1.242
2.088GluArg: 2.088 ± 0.372
6.263GluSer: 6.263 ± 2.111
1.044GluThr: 1.044 ± 0.993
2.088GluVal: 2.088 ± 1.242
3.132GluTrp: 3.132 ± 1.366
3.132GluTyr: 3.132 ± 1.366
0.0GluXaa: 0.0 ± 0.0
Phe
4.175PheAla: 4.175 ± 2.359
1.044PheCys: 1.044 ± 0.993
3.132PheAsp: 3.132 ± 1.366
4.175PheGlu: 4.175 ± 2.359
0.0PhePhe: 0.0 ± 0.0
2.088PheGly: 2.088 ± 0.372
1.044PheHis: 1.044 ± 0.993
4.175PheIle: 4.175 ± 0.745
0.0PheLys: 0.0 ± 0.0
4.175PheLeu: 4.175 ± 0.745
1.044PheMet: 1.044 ± 0.621
2.088PheAsn: 2.088 ± 1.986
1.044PhePro: 1.044 ± 0.621
2.088PheGln: 2.088 ± 1.242
3.132PheArg: 3.132 ± 2.98
5.219PheSer: 5.219 ± 3.104
0.0PheThr: 0.0 ± 0.0
1.044PheVal: 1.044 ± 0.993
1.044PheTrp: 1.044 ± 0.621
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
7.307GlyAla: 7.307 ± 1.118
1.044GlyCys: 1.044 ± 0.993
2.088GlyAsp: 2.088 ± 0.372
3.132GlyGlu: 3.132 ± 1.863
3.132GlyPhe: 3.132 ± 0.249
4.175GlyGly: 4.175 ± 2.359
2.088GlyHis: 2.088 ± 1.242
6.263GlyIle: 6.263 ± 0.497
6.263GlyLys: 6.263 ± 0.497
3.132GlyLeu: 3.132 ± 1.863
0.0GlyMet: 0.0 ± 0.0
2.088GlyAsn: 2.088 ± 1.242
1.044GlyPro: 1.044 ± 0.621
4.175GlyGln: 4.175 ± 2.359
4.175GlyArg: 4.175 ± 2.359
4.175GlySer: 4.175 ± 2.484
1.044GlyThr: 1.044 ± 0.993
7.307GlyVal: 7.307 ± 1.118
3.132GlyTrp: 3.132 ± 2.98
3.132GlyTyr: 3.132 ± 1.366
0.0GlyXaa: 0.0 ± 0.0
His
2.088HisAla: 2.088 ± 0.372
1.044HisCys: 1.044 ± 0.621
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
1.044HisGly: 1.044 ± 0.993
1.044HisHis: 1.044 ± 0.621
1.044HisIle: 1.044 ± 0.621
1.044HisLys: 1.044 ± 0.993
4.175HisLeu: 4.175 ± 0.745
1.044HisMet: 1.044 ± 0.993
0.0HisAsn: 0.0 ± 0.0
1.044HisPro: 1.044 ± 0.993
0.0HisGln: 0.0 ± 0.0
1.044HisArg: 1.044 ± 0.993
1.044HisSer: 1.044 ± 0.621
1.044HisThr: 1.044 ± 0.993
4.175HisVal: 4.175 ± 2.484
0.0HisTrp: 0.0 ± 0.0
1.044HisTyr: 1.044 ± 0.993
0.0HisXaa: 0.0 ± 0.0
Ile
2.088IleAla: 2.088 ± 0.372
0.0IleCys: 0.0 ± 0.0
0.0IleAsp: 0.0 ± 0.0
3.132IleGlu: 3.132 ± 1.366
2.088IlePhe: 2.088 ± 1.986
3.132IleGly: 3.132 ± 1.863
1.044IleHis: 1.044 ± 0.621
3.132IleIle: 3.132 ± 0.249
2.088IleLys: 2.088 ± 0.372
5.219IleLeu: 5.219 ± 3.104
3.132IleMet: 3.132 ± 2.98
1.044IleAsn: 1.044 ± 0.993
4.175IlePro: 4.175 ± 0.745
1.044IleGln: 1.044 ± 0.621
4.175IleArg: 4.175 ± 0.869
5.219IleSer: 5.219 ± 0.124
1.044IleThr: 1.044 ± 0.993
3.132IleVal: 3.132 ± 1.366
0.0IleTrp: 0.0 ± 0.0
1.044IleTyr: 1.044 ± 0.621
0.0IleXaa: 0.0 ± 0.0
Lys
1.044LysAla: 1.044 ± 0.993
1.044LysCys: 1.044 ± 0.621
4.175LysAsp: 4.175 ± 2.359
1.044LysGlu: 1.044 ± 0.621
2.088LysPhe: 2.088 ± 1.242
3.132LysGly: 3.132 ± 0.249
3.132LysHis: 3.132 ± 1.366
3.132LysIle: 3.132 ± 1.366
2.088LysLys: 2.088 ± 0.372
7.307LysLeu: 7.307 ± 2.732
2.088LysMet: 2.088 ± 1.986
1.044LysAsn: 1.044 ± 0.621
4.175LysPro: 4.175 ± 0.869
1.044LysGln: 1.044 ± 0.621
2.088LysArg: 2.088 ± 0.372
5.219LysSer: 5.219 ± 0.124
3.132LysThr: 3.132 ± 0.249
2.088LysVal: 2.088 ± 1.242
0.0LysTrp: 0.0 ± 0.0
3.132LysTyr: 3.132 ± 0.249
0.0LysXaa: 0.0 ± 0.0
Leu
9.395LeuAla: 9.395 ± 2.36
2.088LeuCys: 2.088 ± 0.372
4.175LeuAsp: 4.175 ± 0.869
7.307LeuGlu: 7.307 ± 1.118
5.219LeuPhe: 5.219 ± 4.966
6.263LeuGly: 6.263 ± 0.497
1.044LeuHis: 1.044 ± 0.993
3.132LeuIle: 3.132 ± 0.249
2.088LeuLys: 2.088 ± 0.372
8.351LeuLeu: 8.351 ± 0.125
1.044LeuMet: 1.044 ± 0.993
1.044LeuAsn: 1.044 ± 0.621
2.088LeuPro: 2.088 ± 1.242
4.175LeuGln: 4.175 ± 0.869
11.482LeuArg: 11.482 ± 1.241
7.307LeuSer: 7.307 ± 2.11
2.088LeuThr: 2.088 ± 1.242
9.395LeuVal: 9.395 ± 2.36
1.044LeuTrp: 1.044 ± 0.621
4.175LeuTyr: 4.175 ± 2.359
0.0LeuXaa: 0.0 ± 0.0
Met
1.044MetAla: 1.044 ± 0.621
1.044MetCys: 1.044 ± 0.621
2.088MetAsp: 2.088 ± 0.372
1.044MetGlu: 1.044 ± 0.993
1.044MetPhe: 1.044 ± 0.621
5.219MetGly: 5.219 ± 1.738
0.0MetHis: 0.0 ± 0.0
1.044MetIle: 1.044 ± 0.993
2.088MetLys: 2.088 ± 0.372
4.175MetLeu: 4.175 ± 3.973
1.044MetMet: 1.044 ± 0.621
0.0MetAsn: 0.0 ± 0.0
1.044MetPro: 1.044 ± 0.621
1.044MetGln: 1.044 ± 0.993
1.044MetArg: 1.044 ± 0.621
2.088MetSer: 2.088 ± 1.986
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
2.088MetTrp: 2.088 ± 0.372
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
0.0AsnAla: 0.0 ± 0.0
0.0AsnCys: 0.0 ± 0.0
1.044AsnAsp: 1.044 ± 0.993
2.088AsnGlu: 2.088 ± 1.986
0.0AsnPhe: 0.0 ± 0.0
1.044AsnGly: 1.044 ± 0.621
0.0AsnHis: 0.0 ± 0.0
0.0AsnIle: 0.0 ± 0.0
2.088AsnLys: 2.088 ± 1.986
3.132AsnLeu: 3.132 ± 1.366
2.088AsnMet: 2.088 ± 0.372
2.088AsnAsn: 2.088 ± 0.372
4.175AsnPro: 4.175 ± 2.484
0.0AsnGln: 0.0 ± 0.0
2.088AsnArg: 2.088 ± 0.372
1.044AsnSer: 1.044 ± 0.993
2.088AsnThr: 2.088 ± 0.372
0.0AsnVal: 0.0 ± 0.0
4.175AsnTrp: 4.175 ± 0.869
2.088AsnTyr: 2.088 ± 1.242
0.0AsnXaa: 0.0 ± 0.0
Pro
5.219ProAla: 5.219 ± 1.49
2.088ProCys: 2.088 ± 1.242
3.132ProAsp: 3.132 ± 1.366
6.263ProGlu: 6.263 ± 0.497
1.044ProPhe: 1.044 ± 0.621
2.088ProGly: 2.088 ± 0.372
2.088ProHis: 2.088 ± 0.372
2.088ProIle: 2.088 ± 0.372
3.132ProLys: 3.132 ± 1.863
3.132ProLeu: 3.132 ± 1.366
0.0ProMet: 0.0 ± 0.0
1.044ProAsn: 1.044 ± 0.993
3.132ProPro: 3.132 ± 1.863
2.088ProGln: 2.088 ± 1.242
2.088ProArg: 2.088 ± 1.242
4.175ProSer: 4.175 ± 0.869
2.088ProThr: 2.088 ± 0.372
6.263ProVal: 6.263 ± 2.111
0.0ProTrp: 0.0 ± 0.0
1.044ProTyr: 1.044 ± 0.993
0.0ProXaa: 0.0 ± 0.0
Gln
4.175GlnAla: 4.175 ± 2.484
0.0GlnCys: 0.0 ± 0.0
1.044GlnAsp: 1.044 ± 0.621
5.219GlnGlu: 5.219 ± 1.49
2.088GlnPhe: 2.088 ± 1.986
2.088GlnGly: 2.088 ± 1.986
1.044GlnHis: 1.044 ± 0.621
3.132GlnIle: 3.132 ± 0.249
1.044GlnLys: 1.044 ± 0.993
5.219GlnLeu: 5.219 ± 1.49
3.132GlnMet: 3.132 ± 1.366
1.044GlnAsn: 1.044 ± 0.621
1.044GlnPro: 1.044 ± 0.621
2.088GlnGln: 2.088 ± 1.242
2.088GlnArg: 2.088 ± 0.372
3.132GlnSer: 3.132 ± 1.863
1.044GlnThr: 1.044 ± 0.621
2.088GlnVal: 2.088 ± 1.242
0.0GlnTrp: 0.0 ± 0.0
1.044GlnTyr: 1.044 ± 0.993
0.0GlnXaa: 0.0 ± 0.0
Arg
6.263ArgAla: 6.263 ± 0.497
1.044ArgCys: 1.044 ± 0.621
2.088ArgAsp: 2.088 ± 0.372
4.175ArgGlu: 4.175 ± 0.745
3.132ArgPhe: 3.132 ± 2.98
1.044ArgGly: 1.044 ± 0.621
0.0ArgHis: 0.0 ± 0.0
3.132ArgIle: 3.132 ± 2.98
2.088ArgLys: 2.088 ± 0.372
7.307ArgLeu: 7.307 ± 1.118
0.0ArgMet: 0.0 ± 0.0
1.044ArgAsn: 1.044 ± 0.621
4.175ArgPro: 4.175 ± 2.484
4.175ArgGln: 4.175 ± 0.869
2.088ArgArg: 2.088 ± 0.372
8.351ArgSer: 8.351 ± 0.125
4.175ArgThr: 4.175 ± 0.745
7.307ArgVal: 7.307 ± 0.496
0.0ArgTrp: 0.0 ± 0.0
2.088ArgTyr: 2.088 ± 0.372
0.0ArgXaa: 0.0 ± 0.0
Ser
10.438SerAla: 10.438 ± 2.981
1.044SerCys: 1.044 ± 0.621
4.175SerAsp: 4.175 ± 0.745
1.044SerGlu: 1.044 ± 0.621
4.175SerPhe: 4.175 ± 2.484
4.175SerGly: 4.175 ± 0.745
0.0SerHis: 0.0 ± 0.0
2.088SerIle: 2.088 ± 0.372
6.263SerLys: 6.263 ± 2.111
6.263SerLeu: 6.263 ± 0.497
2.088SerMet: 2.088 ± 0.996
3.132SerAsn: 3.132 ± 1.366
2.088SerPro: 2.088 ± 1.986
6.263SerGln: 6.263 ± 2.111
5.219SerArg: 5.219 ± 0.124
7.307SerSer: 7.307 ± 1.118
4.175SerThr: 4.175 ± 0.869
7.307SerVal: 7.307 ± 1.118
1.044SerTrp: 1.044 ± 0.993
3.132SerTyr: 3.132 ± 0.249
0.0SerXaa: 0.0 ± 0.0
Thr
3.132ThrAla: 3.132 ± 2.98
1.044ThrCys: 1.044 ± 0.621
3.132ThrAsp: 3.132 ± 1.863
1.044ThrGlu: 1.044 ± 0.621
0.0ThrPhe: 0.0 ± 0.0
2.088ThrGly: 2.088 ± 1.986
1.044ThrHis: 1.044 ± 0.993
2.088ThrIle: 2.088 ± 0.372
0.0ThrLys: 0.0 ± 0.0
4.175ThrLeu: 4.175 ± 2.359
0.0ThrMet: 0.0 ± 0.0
3.132ThrAsn: 3.132 ± 0.249
0.0ThrPro: 0.0 ± 0.0
2.088ThrGln: 2.088 ± 1.242
3.132ThrArg: 3.132 ± 1.863
2.088ThrSer: 2.088 ± 0.372
2.088ThrThr: 2.088 ± 1.242
2.088ThrVal: 2.088 ± 0.372
2.088ThrTrp: 2.088 ± 1.986
2.088ThrTyr: 2.088 ± 1.242
0.0ThrXaa: 0.0 ± 0.0
Val
6.263ValAla: 6.263 ± 2.111
4.175ValCys: 4.175 ± 0.869
2.088ValAsp: 2.088 ± 1.986
3.132ValGlu: 3.132 ± 0.249
4.175ValPhe: 4.175 ± 0.869
6.263ValGly: 6.263 ± 0.497
0.0ValHis: 0.0 ± 0.0
1.044ValIle: 1.044 ± 0.621
10.438ValLys: 10.438 ± 4.595
9.395ValLeu: 9.395 ± 3.974
1.044ValMet: 1.044 ± 0.621
3.132ValAsn: 3.132 ± 0.249
5.219ValPro: 5.219 ± 1.49
1.044ValGln: 1.044 ± 0.993
6.263ValArg: 6.263 ± 0.497
7.307ValSer: 7.307 ± 1.118
2.088ValThr: 2.088 ± 1.242
9.395ValVal: 9.395 ± 3.974
1.044ValTrp: 1.044 ± 0.621
1.044ValTyr: 1.044 ± 0.621
0.0ValXaa: 0.0 ± 0.0
Trp
1.044TrpAla: 1.044 ± 0.993
0.0TrpCys: 0.0 ± 0.0
2.088TrpAsp: 2.088 ± 1.986
0.0TrpGlu: 0.0 ± 0.0
2.088TrpPhe: 2.088 ± 1.986
2.088TrpGly: 2.088 ± 1.242
1.044TrpHis: 1.044 ± 0.621
2.088TrpIle: 2.088 ± 0.372
2.088TrpLys: 2.088 ± 1.986
2.088TrpLeu: 2.088 ± 0.372
1.044TrpMet: 1.044 ± 0.993
1.044TrpAsn: 1.044 ± 0.621
1.044TrpPro: 1.044 ± 0.621
2.088TrpGln: 2.088 ± 1.986
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
3.132TrpThr: 3.132 ± 1.366
3.132TrpVal: 3.132 ± 0.249
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
0.0TyrCys: 0.0 ± 0.0
2.088TyrAsp: 2.088 ± 1.242
2.088TyrGlu: 2.088 ± 0.372
4.175TyrPhe: 4.175 ± 0.745
2.088TyrGly: 2.088 ± 1.242
1.044TyrHis: 1.044 ± 0.993
0.0TyrIle: 0.0 ± 0.0
2.088TyrLys: 2.088 ± 1.986
3.132TyrLeu: 3.132 ± 1.366
3.132TyrMet: 3.132 ± 1.894
1.044TyrAsn: 1.044 ± 0.621
2.088TyrPro: 2.088 ± 0.372
2.088TyrGln: 2.088 ± 1.242
1.044TyrArg: 1.044 ± 0.993
3.132TyrSer: 3.132 ± 0.249
0.0TyrThr: 0.0 ± 0.0
2.088TyrVal: 2.088 ± 1.242
1.044TyrTrp: 1.044 ± 0.993
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (959 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski