Ursus maritimus (Polar bear) (Thalarctos maritimus)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Laurasiatheria;

Average proteome isoelectric point is 6.76

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 25970 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A384DKV9|A0A384DKV9_URSMA Galectin OS=Ursus maritimus OX=29073 GN=LOC103679897 PE=4 SV=1
DDD2 pKa = 4.43MLLRR6 pKa = 11.84LAEEE10 pKa = 4.18AQITDDD16 pKa = 3.38VRR18 pKa = 11.84VLDDD22 pKa = 5.37PTQEEE27 pKa = 4.42QLGSTCYYY35 pKa = 9.98SGWGSVEEE43 pKa = 3.63DDD45 pKa = 2.95KK46 pKa = 11.07VYYY49 pKa = 10.16DDD51 pKa = 4.2DD52 pKa = 4.31QCVDDD57 pKa = 5.31EEE59 pKa = 4.32LSNDDD64 pKa = 3.05CAKKK68 pKa = 9.9HHH70 pKa = 4.89QKKK73 pKa = 9.09TEEE76 pKa = 4.94MLCAGQLEEE85 pKa = 4.69GKKK88 pKa = 8.05DD89 pKa = 3.21CAGDDD94 pKa = 3.05GGPLICDDD102 pKa = 3.58VLQGITSW

Molecular weight: 11.7 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A384DEZ4|A0A384DEZ4_URSMA protein EMSY isoform X1 OS=Ursus maritimus OX=29073 GN=LOC103678066 PE=4 SV=1
MM1 pKa = 7.57SSHH4 pKa = 5.15KK5 pKa = 8.91TFRR8 pKa = 11.84IKK10 pKa = 10.64RR11 pKa = 11.84FLAKK15 pKa = 9.71KK16 pKa = 9.58QKK18 pKa = 8.69QNRR21 pKa = 11.84PIPQWIRR28 pKa = 11.84MKK30 pKa = 9.89TGNKK34 pKa = 8.61IRR36 pKa = 11.84YY37 pKa = 7.09NSKK40 pKa = 8.3RR41 pKa = 11.84RR42 pKa = 11.84HH43 pKa = 3.95WRR45 pKa = 11.84RR46 pKa = 11.84TKK48 pKa = 10.83LGLL51 pKa = 3.67

Molecular weight: 6.41 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

19368

6602

25970

14166585

27

34289

545.5

60.86

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.705 ± 0.013

2.267 ± 0.013

4.768 ± 0.012

7.052 ± 0.022

3.765 ± 0.012

6.405 ± 0.022

2.622 ± 0.008

4.468 ± 0.014

5.821 ± 0.019

9.968 ± 0.021

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.183 ± 0.008

3.644 ± 0.011

6.142 ± 0.021

4.739 ± 0.014

5.583 ± 0.015

8.383 ± 0.019

5.398 ± 0.013

6.12 ± 0.014

1.216 ± 0.006

2.691 ± 0.009
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski