Amino acid dipepetide frequency for Avian metaavulavirus 8

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.198AlaAla: 4.198 ± 0.928
0.8AlaCys: 0.8 ± 0.371
3.199AlaAsp: 3.199 ± 0.72
2.799AlaGlu: 2.799 ± 0.414
1.399AlaPhe: 1.399 ± 0.695
3.599AlaGly: 3.599 ± 1.256
0.8AlaHis: 0.8 ± 0.371
4.998AlaIle: 4.998 ± 0.616
2.799AlaLys: 2.799 ± 1.1
6.997AlaLeu: 6.997 ± 2.344
1.999AlaMet: 1.999 ± 0.678
2.199AlaAsn: 2.199 ± 0.593
2.399AlaPro: 2.399 ± 0.6
2.799AlaGln: 2.799 ± 1.059
3.998AlaArg: 3.998 ± 0.756
6.198AlaSer: 6.198 ± 1.23
3.599AlaThr: 3.599 ± 0.982
4.198AlaVal: 4.198 ± 1.472
0.2AlaTrp: 0.2 ± 0.282
1.399AlaTyr: 1.399 ± 0.389
0.0AlaXaa: 0.0 ± 0.0
Cys
1.0CysAla: 1.0 ± 0.292
0.4CysCys: 0.4 ± 0.256
1.399CysAsp: 1.399 ± 0.709
0.8CysGlu: 0.8 ± 0.331
0.8CysPhe: 0.8 ± 0.344
0.4CysGly: 0.4 ± 0.386
0.2CysHis: 0.2 ± 0.132
0.8CysIle: 0.8 ± 0.283
1.799CysLys: 1.799 ± 0.577
2.199CysLeu: 2.199 ± 0.488
0.4CysMet: 0.4 ± 0.264
1.2CysAsn: 1.2 ± 0.435
0.6CysPro: 0.6 ± 0.301
1.399CysGln: 1.399 ± 0.46
1.399CysArg: 1.399 ± 0.661
1.799CysSer: 1.799 ± 0.44
1.2CysThr: 1.2 ± 0.427
1.2CysVal: 1.2 ± 0.425
0.0CysTrp: 0.0 ± 0.0
0.4CysTyr: 0.4 ± 0.19
0.0CysXaa: 0.0 ± 0.0
Asp
3.199AspAla: 3.199 ± 0.949
0.6AspCys: 0.6 ± 0.234
3.798AspAsp: 3.798 ± 0.686
3.199AspGlu: 3.199 ± 0.821
1.999AspPhe: 1.999 ± 0.45
2.599AspGly: 2.599 ± 0.776
1.0AspHis: 1.0 ± 0.482
5.598AspIle: 5.598 ± 0.821
2.399AspLys: 2.399 ± 1.139
6.198AspLeu: 6.198 ± 0.891
0.8AspMet: 0.8 ± 0.413
2.999AspAsn: 2.999 ± 0.787
3.599AspPro: 3.599 ± 0.98
1.799AspGln: 1.799 ± 0.521
2.399AspArg: 2.399 ± 0.504
2.999AspSer: 2.999 ± 0.703
3.998AspThr: 3.998 ± 0.801
2.199AspVal: 2.199 ± 0.556
0.0AspTrp: 0.0 ± 0.0
1.599AspTyr: 1.599 ± 0.51
0.0AspXaa: 0.0 ± 0.0
Glu
1.599GluAla: 1.599 ± 0.524
1.599GluCys: 1.599 ± 0.582
1.799GluAsp: 1.799 ± 0.556
4.998GluGlu: 4.998 ± 1.79
2.199GluPhe: 2.199 ± 0.86
2.999GluGly: 2.999 ± 0.72
0.8GluHis: 0.8 ± 0.283
6.198GluIle: 6.198 ± 1.642
3.998GluLys: 3.998 ± 1.273
5.398GluLeu: 5.398 ± 1.413
1.2GluMet: 1.2 ± 0.594
2.399GluAsn: 2.399 ± 0.593
1.2GluPro: 1.2 ± 0.616
1.999GluGln: 1.999 ± 0.896
0.8GluArg: 0.8 ± 0.371
3.998GluSer: 3.998 ± 0.758
3.599GluThr: 3.599 ± 0.632
2.199GluVal: 2.199 ± 0.32
1.0GluTrp: 1.0 ± 0.363
2.799GluTyr: 2.799 ± 0.999
0.0GluXaa: 0.0 ± 0.0
Phe
1.999PheAla: 1.999 ± 0.356
0.6PheCys: 0.6 ± 0.245
1.599PheAsp: 1.599 ± 0.873
1.0PheGlu: 1.0 ± 0.66
2.199PhePhe: 2.199 ± 0.906
2.399PheGly: 2.399 ± 0.493
1.2PheHis: 1.2 ± 1.217
1.799PheIle: 1.799 ± 0.524
2.399PheLys: 2.399 ± 0.964
3.199PheLeu: 3.199 ± 1.129
0.8PheMet: 0.8 ± 0.367
2.399PheAsn: 2.399 ± 1.009
0.6PhePro: 0.6 ± 0.504
0.2PheGln: 0.2 ± 0.132
1.599PheArg: 1.599 ± 0.379
2.999PheSer: 2.999 ± 0.853
1.799PheThr: 1.799 ± 0.49
2.999PheVal: 2.999 ± 0.488
0.2PheTrp: 0.2 ± 0.218
0.4PheTyr: 0.4 ± 0.19
0.0PheXaa: 0.0 ± 0.0
Gly
2.399GlyAla: 2.399 ± 0.756
1.0GlyCys: 1.0 ± 0.814
4.398GlyAsp: 4.398 ± 1.2
2.799GlyGlu: 2.799 ± 0.286
2.199GlyPhe: 2.199 ± 1.234
2.399GlyGly: 2.399 ± 0.558
2.199GlyHis: 2.199 ± 0.672
3.199GlyIle: 3.199 ± 0.691
2.199GlyLys: 2.199 ± 1.441
4.398GlyLeu: 4.398 ± 0.624
0.6GlyMet: 0.6 ± 0.396
3.998GlyAsn: 3.998 ± 1.662
2.199GlyPro: 2.199 ± 0.309
1.599GlyGln: 1.599 ± 0.318
3.599GlyArg: 3.599 ± 1.089
4.398GlySer: 4.398 ± 0.961
3.599GlyThr: 3.599 ± 1.017
3.599GlyVal: 3.599 ± 1.143
0.0GlyTrp: 0.0 ± 0.0
1.0GlyTyr: 1.0 ± 0.446
0.0GlyXaa: 0.0 ± 0.0
His
1.0HisAla: 1.0 ± 0.619
0.2HisCys: 0.2 ± 0.132
1.399HisAsp: 1.399 ± 0.72
0.2HisGlu: 0.2 ± 0.132
0.2HisPhe: 0.2 ± 0.132
1.0HisGly: 1.0 ± 0.352
0.8HisHis: 0.8 ± 0.528
2.199HisIle: 2.199 ± 0.568
0.8HisLys: 0.8 ± 0.528
1.999HisLeu: 1.999 ± 0.909
0.4HisMet: 0.4 ± 0.19
1.399HisAsn: 1.399 ± 0.512
2.399HisPro: 2.399 ± 0.825
0.8HisGln: 0.8 ± 0.287
0.6HisArg: 0.6 ± 0.262
1.399HisSer: 1.399 ± 0.478
0.8HisThr: 0.8 ± 0.528
0.6HisVal: 0.6 ± 0.245
0.6HisTrp: 0.6 ± 0.546
0.4HisTyr: 0.4 ± 0.264
0.0HisXaa: 0.0 ± 0.0
Ile
6.397IleAla: 6.397 ± 1.223
1.0IleCys: 1.0 ± 0.446
3.998IleAsp: 3.998 ± 0.567
3.399IleGlu: 3.399 ± 0.746
2.999IlePhe: 2.999 ± 0.783
5.398IleGly: 5.398 ± 1.717
1.599IleHis: 1.599 ± 0.451
4.398IleIle: 4.398 ± 1.242
6.797IleLys: 6.797 ± 0.931
5.998IleLeu: 5.998 ± 1.589
1.599IleMet: 1.599 ± 0.418
3.199IleAsn: 3.199 ± 0.751
3.798IlePro: 3.798 ± 1.297
4.398IleGln: 4.398 ± 0.852
2.799IleArg: 2.799 ± 0.954
8.197IleSer: 8.197 ± 1.167
3.399IleThr: 3.399 ± 1.051
3.998IleVal: 3.998 ± 1.676
1.2IleTrp: 1.2 ± 0.687
1.799IleTyr: 1.799 ± 0.381
0.0IleXaa: 0.0 ± 0.0
Lys
1.999LysAla: 1.999 ± 1.012
1.0LysCys: 1.0 ± 0.482
1.999LysAsp: 1.999 ± 0.477
4.998LysGlu: 4.998 ± 1.13
2.199LysPhe: 2.199 ± 0.372
2.399LysGly: 2.399 ± 0.992
0.8LysHis: 0.8 ± 0.528
2.999LysIle: 2.999 ± 0.96
2.999LysLys: 2.999 ± 1.521
5.398LysLeu: 5.398 ± 1.743
1.999LysMet: 1.999 ± 0.741
2.199LysAsn: 2.199 ± 0.803
2.399LysPro: 2.399 ± 1.442
2.599LysGln: 2.599 ± 0.597
2.799LysArg: 2.799 ± 0.842
6.597LysSer: 6.597 ± 1.074
3.399LysThr: 3.399 ± 0.622
2.399LysVal: 2.399 ± 0.78
0.2LysTrp: 0.2 ± 0.132
1.0LysTyr: 1.0 ± 0.264
0.0LysXaa: 0.0 ± 0.0
Leu
6.597LeuAla: 6.597 ± 1.128
2.599LeuCys: 2.599 ± 0.814
5.998LeuAsp: 5.998 ± 0.591
6.397LeuGlu: 6.397 ± 1.113
3.199LeuPhe: 3.199 ± 1.501
4.798LeuGly: 4.798 ± 1.104
2.799LeuHis: 2.799 ± 0.683
5.798LeuIle: 5.798 ± 1.006
6.397LeuLys: 6.397 ± 0.721
8.397LeuLeu: 8.397 ± 1.568
1.999LeuMet: 1.999 ± 0.942
4.798LeuAsn: 4.798 ± 1.034
3.199LeuPro: 3.199 ± 0.747
3.798LeuGln: 3.798 ± 0.964
4.198LeuArg: 4.198 ± 0.922
10.796LeuSer: 10.796 ± 1.858
7.997LeuThr: 7.997 ± 1.226
6.198LeuVal: 6.198 ± 0.908
2.199LeuTrp: 2.199 ± 0.82
3.798LeuTyr: 3.798 ± 0.777
0.0LeuXaa: 0.0 ± 0.0
Met
1.799MetAla: 1.799 ± 0.691
0.6MetCys: 0.6 ± 0.262
2.199MetAsp: 2.199 ± 0.735
0.4MetGlu: 0.4 ± 0.264
0.6MetPhe: 0.6 ± 0.592
1.599MetGly: 1.599 ± 1.036
0.4MetHis: 0.4 ± 0.264
1.399MetIle: 1.399 ± 0.727
0.4MetLys: 0.4 ± 0.186
2.199MetLeu: 2.199 ± 0.471
0.4MetMet: 0.4 ± 0.346
0.8MetAsn: 0.8 ± 0.344
0.8MetPro: 0.8 ± 0.528
0.4MetGln: 0.4 ± 0.284
1.799MetArg: 1.799 ± 0.495
2.599MetSer: 2.599 ± 0.503
1.599MetThr: 1.599 ± 0.324
1.0MetVal: 1.0 ± 0.434
0.2MetTrp: 0.2 ± 0.132
1.0MetTyr: 1.0 ± 0.317
0.0MetXaa: 0.0 ± 0.0
Asn
2.799AsnAla: 2.799 ± 0.697
0.6AsnCys: 0.6 ± 0.234
2.199AsnAsp: 2.199 ± 1.117
2.799AsnGlu: 2.799 ± 0.496
1.0AsnPhe: 1.0 ± 0.351
2.399AsnGly: 2.399 ± 0.56
0.4AsnHis: 0.4 ± 0.264
4.598AsnIle: 4.598 ± 0.874
1.999AsnLys: 1.999 ± 0.787
5.598AsnLeu: 5.598 ± 1.226
1.599AsnMet: 1.599 ± 0.438
1.399AsnAsn: 1.399 ± 0.834
3.199AsnPro: 3.199 ± 0.693
5.198AsnGln: 5.198 ± 1.176
1.399AsnArg: 1.399 ± 0.492
5.198AsnSer: 5.198 ± 0.416
3.599AsnThr: 3.599 ± 1.362
1.0AsnVal: 1.0 ± 0.597
0.4AsnTrp: 0.4 ± 0.264
2.799AsnTyr: 2.799 ± 0.69
0.0AsnXaa: 0.0 ± 0.0
Pro
2.199ProAla: 2.199 ± 1.046
0.0ProCys: 0.0 ± 0.0
2.399ProAsp: 2.399 ± 0.47
3.199ProGlu: 3.199 ± 0.777
1.0ProPhe: 1.0 ± 0.351
2.599ProGly: 2.599 ± 1.117
0.4ProHis: 0.4 ± 0.362
3.199ProIle: 3.199 ± 0.942
1.999ProLys: 1.999 ± 0.677
3.998ProLeu: 3.998 ± 0.591
1.2ProMet: 1.2 ± 0.345
1.599ProAsn: 1.599 ± 0.7
3.199ProPro: 3.199 ± 1.58
3.199ProGln: 3.199 ± 1.724
2.399ProArg: 2.399 ± 0.411
3.798ProSer: 3.798 ± 0.887
2.999ProThr: 2.999 ± 1.225
3.199ProVal: 3.199 ± 0.666
0.4ProTrp: 0.4 ± 0.225
1.999ProTyr: 1.999 ± 0.747
0.0ProXaa: 0.0 ± 0.0
Gln
2.399GlnAla: 2.399 ± 1.293
0.6GlnCys: 0.6 ± 0.262
2.199GlnAsp: 2.199 ± 0.386
1.799GlnGlu: 1.799 ± 0.401
1.999GlnPhe: 1.999 ± 0.471
2.999GlnGly: 2.999 ± 0.999
0.2GlnHis: 0.2 ± 0.132
3.599GlnIle: 3.599 ± 0.776
1.799GlnLys: 1.799 ± 0.295
5.598GlnLeu: 5.598 ± 1.061
0.6GlnMet: 0.6 ± 0.396
2.399GlnAsn: 2.399 ± 1.436
1.2GlnPro: 1.2 ± 0.459
2.599GlnGln: 2.599 ± 0.669
1.399GlnArg: 1.399 ± 0.709
4.998GlnSer: 4.998 ± 1.611
2.999GlnThr: 2.999 ± 1.173
4.798GlnVal: 4.798 ± 1.037
0.4GlnTrp: 0.4 ± 0.264
1.999GlnTyr: 1.999 ± 0.377
0.0GlnXaa: 0.0 ± 0.0
Arg
3.798ArgAla: 3.798 ± 0.646
1.0ArgCys: 1.0 ± 0.327
1.399ArgAsp: 1.399 ± 0.485
1.999ArgGlu: 1.999 ± 0.5
1.0ArgPhe: 1.0 ± 0.673
2.399ArgGly: 2.399 ± 0.6
1.399ArgHis: 1.399 ± 0.531
3.798ArgIle: 3.798 ± 0.914
1.999ArgLys: 1.999 ± 0.92
5.398ArgLeu: 5.398 ± 1.89
0.4ArgMet: 0.4 ± 0.421
2.999ArgAsn: 2.999 ± 0.795
2.399ArgPro: 2.399 ± 0.989
1.2ArgGln: 1.2 ± 0.368
1.999ArgArg: 1.999 ± 0.703
4.798ArgSer: 4.798 ± 1.043
2.399ArgThr: 2.399 ± 0.834
3.798ArgVal: 3.798 ± 0.65
0.8ArgTrp: 0.8 ± 0.379
1.2ArgTyr: 1.2 ± 0.368
0.0ArgXaa: 0.0 ± 0.0
Ser
5.198SerAla: 5.198 ± 0.627
2.799SerCys: 2.799 ± 0.579
4.798SerAsp: 4.798 ± 0.997
5.798SerGlu: 5.798 ± 1.055
2.999SerPhe: 2.999 ± 0.747
3.798SerGly: 3.798 ± 0.538
2.799SerHis: 2.799 ± 0.801
8.197SerIle: 8.197 ± 1.998
4.398SerLys: 4.398 ± 1.05
11.795SerLeu: 11.795 ± 2.678
2.799SerMet: 2.799 ± 0.927
4.198SerAsn: 4.198 ± 0.669
3.199SerPro: 3.199 ± 0.78
4.598SerGln: 4.598 ± 0.823
5.198SerArg: 5.198 ± 0.694
12.395SerSer: 12.395 ± 2.655
5.398SerThr: 5.398 ± 0.778
6.597SerVal: 6.597 ± 1.311
1.599SerTrp: 1.599 ± 0.566
1.599SerTyr: 1.599 ± 0.443
0.0SerXaa: 0.0 ± 0.0
Thr
5.598ThrAla: 5.598 ± 0.892
1.599ThrCys: 1.599 ± 0.617
2.799ThrAsp: 2.799 ± 0.477
2.199ThrGlu: 2.199 ± 0.661
1.799ThrPhe: 1.799 ± 0.742
2.999ThrGly: 2.999 ± 0.759
1.0ThrHis: 1.0 ± 0.412
5.998ThrIle: 5.998 ± 1.48
2.999ThrLys: 2.999 ± 1.085
6.397ThrLeu: 6.397 ± 1.036
1.0ThrMet: 1.0 ± 0.491
2.799ThrAsn: 2.799 ± 0.821
4.398ThrPro: 4.398 ± 0.96
2.799ThrGln: 2.799 ± 0.745
3.199ThrArg: 3.199 ± 0.467
5.798ThrSer: 5.798 ± 0.846
9.996ThrThr: 9.996 ± 2.43
3.998ThrVal: 3.998 ± 1.544
0.6ThrTrp: 0.6 ± 0.245
1.799ThrTyr: 1.799 ± 0.679
0.0ThrXaa: 0.0 ± 0.0
Val
3.798ValAla: 3.798 ± 1.236
1.2ValCys: 1.2 ± 0.425
3.399ValAsp: 3.399 ± 0.699
2.199ValGlu: 2.199 ± 0.448
1.599ValPhe: 1.599 ± 0.49
3.199ValGly: 3.199 ± 0.554
0.4ValHis: 0.4 ± 0.264
4.798ValIle: 4.798 ± 0.87
3.399ValLys: 3.399 ± 0.577
5.198ValLeu: 5.198 ± 1.27
1.2ValMet: 1.2 ± 0.482
5.998ValAsn: 5.998 ± 1.787
2.599ValPro: 2.599 ± 1.222
2.599ValGln: 2.599 ± 0.845
2.399ValArg: 2.399 ± 0.7
5.798ValSer: 5.798 ± 0.808
5.198ValThr: 5.198 ± 1.663
2.999ValVal: 2.999 ± 0.989
0.0ValTrp: 0.0 ± 0.0
1.599ValTyr: 1.599 ± 0.589
0.0ValXaa: 0.0 ± 0.0
Trp
0.4TrpAla: 0.4 ± 0.19
0.4TrpCys: 0.4 ± 0.369
0.4TrpAsp: 0.4 ± 0.264
0.6TrpGlu: 0.6 ± 0.501
0.2TrpPhe: 0.2 ± 0.282
0.6TrpGly: 0.6 ± 0.522
0.0TrpHis: 0.0 ± 0.0
0.6TrpIle: 0.6 ± 0.245
0.0TrpLys: 0.0 ± 0.0
1.599TrpLeu: 1.599 ± 0.402
0.4TrpMet: 0.4 ± 0.182
0.0TrpAsn: 0.0 ± 0.0
0.6TrpPro: 0.6 ± 0.387
0.6TrpGln: 0.6 ± 0.478
0.8TrpArg: 0.8 ± 0.344
1.799TrpSer: 1.799 ± 0.44
0.4TrpThr: 0.4 ± 0.19
1.0TrpVal: 1.0 ± 0.354
0.2TrpTrp: 0.2 ± 0.218
0.4TrpTyr: 0.4 ± 0.19
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.199TyrAla: 2.199 ± 0.424
0.8TyrCys: 0.8 ± 0.266
1.599TyrAsp: 1.599 ± 0.468
1.2TyrGlu: 1.2 ± 0.276
0.8TyrPhe: 0.8 ± 0.245
1.2TyrGly: 1.2 ± 0.381
0.0TyrHis: 0.0 ± 0.0
2.199TyrIle: 2.199 ± 0.431
0.8TyrLys: 0.8 ± 0.371
3.998TyrLeu: 3.998 ± 1.412
0.6TyrMet: 0.6 ± 0.262
1.2TyrAsn: 1.2 ± 0.391
1.2TyrPro: 1.2 ± 0.905
1.999TyrGln: 1.999 ± 0.538
1.399TyrArg: 1.399 ± 0.422
3.599TyrSer: 3.599 ± 0.864
1.799TyrThr: 1.799 ± 0.578
1.599TyrVal: 1.599 ± 0.662
0.8TyrTrp: 0.8 ± 0.262
0.6TyrTyr: 0.6 ± 0.234
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (5003 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski