Amino acid dipepetide frequency for Sanxia water strider virus 7

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.968AlaAla: 2.968 ± 1.493
0.66AlaCys: 0.66 ± 0.332
3.298AlaAsp: 3.298 ± 0.996
1.979AlaGlu: 1.979 ± 0.995
3.298AlaPhe: 3.298 ± 1.015
2.968AlaGly: 2.968 ± 1.057
1.979AlaHis: 1.979 ± 0.995
5.277AlaIle: 5.277 ± 1.087
2.639AlaLys: 2.639 ± 1.785
4.617AlaLeu: 4.617 ± 0.779
0.0AlaMet: 0.0 ± 0.0
1.979AlaAsn: 1.979 ± 0.542
2.639AlaPro: 2.639 ± 0.454
0.989AlaGln: 0.989 ± 0.566
2.639AlaArg: 2.639 ± 1.08
3.958AlaSer: 3.958 ± 0.503
3.298AlaThr: 3.298 ± 2.878
5.277AlaVal: 5.277 ± 2.131
1.319AlaTrp: 1.319 ± 0.86
1.649AlaTyr: 1.649 ± 0.498
0.0AlaXaa: 0.0 ± 0.0
Cys
1.649CysAla: 1.649 ± 0.498
0.33CysCys: 0.33 ± 0.166
0.989CysAsp: 0.989 ± 0.498
1.649CysGlu: 1.649 ± 0.829
1.649CysPhe: 1.649 ± 0.498
0.989CysGly: 0.989 ± 0.498
0.0CysHis: 0.0 ± 0.0
1.319CysIle: 1.319 ± 0.664
0.66CysLys: 0.66 ± 0.332
0.989CysLeu: 0.989 ± 0.498
0.989CysMet: 0.989 ± 0.498
1.319CysAsn: 1.319 ± 0.664
0.66CysPro: 0.66 ± 0.663
0.989CysGln: 0.989 ± 0.498
2.309CysArg: 2.309 ± 1.161
1.649CysSer: 1.649 ± 0.839
2.639CysThr: 2.639 ± 1.327
0.33CysVal: 0.33 ± 0.166
0.33CysTrp: 0.33 ± 0.166
1.319CysTyr: 1.319 ± 0.664
0.0CysXaa: 0.0 ± 0.0
Asp
3.298AspAla: 3.298 ± 3.81
2.309AspCys: 2.309 ± 1.161
3.298AspAsp: 3.298 ± 1.659
3.298AspGlu: 3.298 ± 1.015
3.958AspPhe: 3.958 ± 0.433
1.979AspGly: 1.979 ± 0.852
0.989AspHis: 0.989 ± 0.498
4.617AspIle: 4.617 ± 0.779
3.298AspLys: 3.298 ± 0.996
5.937AspLeu: 5.937 ± 1.832
0.66AspMet: 0.66 ± 0.663
1.979AspAsn: 1.979 ± 0.995
3.298AspPro: 3.298 ± 1.731
1.319AspGln: 1.319 ± 0.507
4.288AspArg: 4.288 ± 0.635
4.617AspSer: 4.617 ± 1.694
2.309AspThr: 2.309 ± 0.629
3.628AspVal: 3.628 ± 1.286
1.319AspTrp: 1.319 ± 0.664
2.968AspTyr: 2.968 ± 1.057
0.0AspXaa: 0.0 ± 0.0
Glu
1.979GluAla: 1.979 ± 0.542
1.649GluCys: 1.649 ± 0.498
2.968GluAsp: 2.968 ± 1.699
3.298GluGlu: 3.298 ± 1.731
2.968GluPhe: 2.968 ± 0.368
3.298GluGly: 3.298 ± 0.753
0.989GluHis: 0.989 ± 0.498
4.617GluIle: 4.617 ± 1.065
2.639GluLys: 2.639 ± 1.785
4.288GluLeu: 4.288 ± 0.283
2.309GluMet: 2.309 ± 1.161
2.639GluAsn: 2.639 ± 0.743
2.309GluPro: 2.309 ± 0.629
2.968GluGln: 2.968 ± 1.691
0.989GluArg: 0.989 ± 0.498
5.937GluSer: 5.937 ± 2.051
2.309GluThr: 2.309 ± 1.062
3.298GluVal: 3.298 ± 0.346
0.33GluTrp: 0.33 ± 0.166
1.319GluTyr: 1.319 ± 0.664
0.0GluXaa: 0.0 ± 0.0
Phe
3.958PheAla: 3.958 ± 1.416
2.309PheCys: 2.309 ± 0.576
2.639PheAsp: 2.639 ± 0.454
0.66PheGlu: 0.66 ± 0.332
1.319PhePhe: 1.319 ± 0.507
4.288PheGly: 4.288 ± 1.162
0.989PheHis: 0.989 ± 0.498
2.968PheIle: 2.968 ± 0.874
2.309PheLys: 2.309 ± 1.161
5.277PheLeu: 5.277 ± 1.087
0.33PheMet: 0.33 ± 0.166
3.298PheAsn: 3.298 ± 1.015
2.309PhePro: 2.309 ± 1.763
1.979PheGln: 1.979 ± 0.852
3.628PheArg: 3.628 ± 0.399
4.947PheSer: 4.947 ± 1.366
2.968PheThr: 2.968 ± 0.874
4.617PheVal: 4.617 ± 1.484
1.319PheTrp: 1.319 ± 0.664
2.309PheTyr: 2.309 ± 1.161
0.0PheXaa: 0.0 ± 0.0
Gly
2.968GlyAla: 2.968 ± 0.916
0.989GlyCys: 0.989 ± 0.498
3.298GlyAsp: 3.298 ± 1.679
3.298GlyGlu: 3.298 ± 1.659
4.617GlyPhe: 4.617 ± 1.258
0.989GlyGly: 0.989 ± 0.91
0.66GlyHis: 0.66 ± 0.986
2.309GlyIle: 2.309 ± 1.161
4.617GlyLys: 4.617 ± 1.153
4.947GlyLeu: 4.947 ± 1.785
2.309GlyMet: 2.309 ± 0.629
0.989GlyAsn: 0.989 ± 0.498
1.979GlyPro: 1.979 ± 0.995
1.649GlyGln: 1.649 ± 0.839
1.979GlyArg: 1.979 ± 0.852
2.968GlySer: 2.968 ± 1.057
3.628GlyThr: 3.628 ± 1.58
3.628GlyVal: 3.628 ± 1.35
0.0GlyTrp: 0.0 ± 0.0
1.319GlyTyr: 1.319 ± 0.664
0.33GlyXaa: 0.33 ± 0.166
His
0.66HisAla: 0.66 ± 0.332
0.33HisCys: 0.33 ± 0.166
0.66HisAsp: 0.66 ± 0.986
0.66HisGlu: 0.66 ± 0.332
0.989HisPhe: 0.989 ± 0.498
2.639HisGly: 2.639 ± 0.965
0.0HisHis: 0.0 ± 0.0
1.979HisIle: 1.979 ± 0.716
0.33HisLys: 0.33 ± 0.166
1.979HisLeu: 1.979 ± 0.852
1.319HisMet: 1.319 ± 0.664
0.0HisAsn: 0.0 ± 0.0
1.979HisPro: 1.979 ± 0.995
0.66HisGln: 0.66 ± 0.332
0.33HisArg: 0.33 ± 0.166
0.989HisSer: 0.989 ± 0.498
1.649HisThr: 1.649 ± 0.839
0.989HisVal: 0.989 ± 0.498
0.0HisTrp: 0.0 ± 0.0
1.319HisTyr: 1.319 ± 0.664
0.0HisXaa: 0.0 ± 0.0
Ile
3.298IleAla: 3.298 ± 1.659
1.979IleCys: 1.979 ± 0.995
5.937IleAsp: 5.937 ± 1.405
5.277IleGlu: 5.277 ± 1.087
3.298IlePhe: 3.298 ± 1.015
4.288IleGly: 4.288 ± 1.739
1.319IleHis: 1.319 ± 0.664
3.628IleIle: 3.628 ± 1.58
5.277IleLys: 5.277 ± 1.521
3.958IleLeu: 3.958 ± 1.278
0.66IleMet: 0.66 ± 0.663
2.309IleAsn: 2.309 ± 1.062
5.277IlePro: 5.277 ± 0.298
2.968IleGln: 2.968 ± 1.493
3.958IleArg: 3.958 ± 2.819
5.607IleSer: 5.607 ± 0.734
2.309IleThr: 2.309 ± 1.882
3.958IleVal: 3.958 ± 1.314
0.989IleTrp: 0.989 ± 0.91
2.968IleTyr: 2.968 ± 0.991
0.0IleXaa: 0.0 ± 0.0
Lys
3.628LysAla: 3.628 ± 1.028
0.66LysCys: 0.66 ± 0.332
2.968LysAsp: 2.968 ± 1.537
2.968LysGlu: 2.968 ± 2.544
2.309LysPhe: 2.309 ± 1.161
2.968LysGly: 2.968 ± 0.874
2.309LysHis: 2.309 ± 1.161
2.309LysIle: 2.309 ± 0.629
4.288LysLys: 4.288 ± 3.869
3.298LysLeu: 3.298 ± 1.624
0.66LysMet: 0.66 ± 0.663
1.649LysAsn: 1.649 ± 0.866
4.617LysPro: 4.617 ± 1.709
3.298LysGln: 3.298 ± 3.467
3.628LysArg: 3.628 ± 1.564
6.596LysSer: 6.596 ± 1.3
3.298LysThr: 3.298 ± 3.315
3.628LysVal: 3.628 ± 4.09
2.309LysTrp: 2.309 ± 1.161
2.968LysTyr: 2.968 ± 0.368
0.0LysXaa: 0.0 ± 0.0
Leu
2.968LeuAla: 2.968 ± 0.874
2.639LeuCys: 2.639 ± 1.327
6.926LeuAsp: 6.926 ± 1.229
4.617LeuGlu: 4.617 ± 1.258
2.968LeuPhe: 2.968 ± 1.493
3.958LeuGly: 3.958 ± 0.503
2.309LeuHis: 2.309 ± 1.763
6.926LeuIle: 6.926 ± 1.229
5.607LeuLys: 5.607 ± 1.6
5.277LeuLeu: 5.277 ± 1.38
1.649LeuMet: 1.649 ± 0.683
2.639LeuAsn: 2.639 ± 1.648
4.947LeuPro: 4.947 ± 3.736
3.298LeuGln: 3.298 ± 1.731
2.968LeuArg: 2.968 ± 1.493
7.586LeuSer: 7.586 ± 2.219
2.968LeuThr: 2.968 ± 0.874
6.266LeuVal: 6.266 ± 0.695
0.989LeuTrp: 0.989 ± 0.566
1.979LeuTyr: 1.979 ± 0.852
0.0LeuXaa: 0.0 ± 0.0
Met
1.979MetAla: 1.979 ± 0.716
1.319MetCys: 1.319 ± 0.664
1.649MetAsp: 1.649 ± 0.498
0.66MetGlu: 0.66 ± 0.332
0.989MetPhe: 0.989 ± 0.91
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
2.309MetIle: 2.309 ± 1.161
0.989MetLys: 0.989 ± 0.498
0.989MetLeu: 0.989 ± 2.065
0.0MetMet: 0.0 ± 0.0
0.989MetAsn: 0.989 ± 0.566
0.33MetPro: 0.33 ± 0.166
0.66MetGln: 0.66 ± 0.332
1.319MetArg: 1.319 ± 1.74
4.288MetSer: 4.288 ± 0.635
0.989MetThr: 0.989 ± 0.498
0.66MetVal: 0.66 ± 0.332
0.33MetTrp: 0.33 ± 0.166
0.989MetTyr: 0.989 ± 0.91
0.0MetXaa: 0.0 ± 0.0
Asn
2.309AsnAla: 2.309 ± 1.062
2.309AsnCys: 2.309 ± 0.629
1.319AsnAsp: 1.319 ± 0.86
2.968AsnGlu: 2.968 ± 0.916
1.649AsnPhe: 1.649 ± 0.829
0.66AsnGly: 0.66 ± 0.332
0.989AsnHis: 0.989 ± 0.498
2.639AsnIle: 2.639 ± 0.743
2.639AsnLys: 2.639 ± 0.454
4.288AsnLeu: 4.288 ± 0.283
0.33AsnMet: 0.33 ± 0.166
3.298AsnAsn: 3.298 ± 0.996
2.639AsnPro: 2.639 ± 1.327
1.649AsnGln: 1.649 ± 0.829
2.968AsnArg: 2.968 ± 0.991
4.288AsnSer: 4.288 ± 1.201
2.309AsnThr: 2.309 ± 0.895
2.309AsnVal: 2.309 ± 1.062
0.0AsnTrp: 0.0 ± 0.0
1.319AsnTyr: 1.319 ± 0.507
0.0AsnXaa: 0.0 ± 0.0
Pro
2.309ProAla: 2.309 ± 0.895
1.319ProCys: 1.319 ± 0.664
4.288ProAsp: 4.288 ± 1.225
3.958ProGlu: 3.958 ± 2.265
3.628ProPhe: 3.628 ± 1.35
2.968ProGly: 2.968 ± 1.057
1.649ProHis: 1.649 ± 0.839
3.628ProIle: 3.628 ± 0.399
2.639ProLys: 2.639 ± 2.652
3.628ProLeu: 3.628 ± 1.286
1.979ProMet: 1.979 ± 1.113
3.628ProAsn: 3.628 ± 1.492
2.639ProPro: 2.639 ± 1.08
3.298ProGln: 3.298 ± 0.346
1.979ProArg: 1.979 ± 0.542
3.298ProSer: 3.298 ± 0.753
3.628ProThr: 3.628 ± 0.591
2.639ProVal: 2.639 ± 1.08
0.33ProTrp: 0.33 ± 0.166
2.968ProTyr: 2.968 ± 1.691
0.0ProXaa: 0.0 ± 0.0
Gln
3.298GlnAla: 3.298 ± 1.015
0.0GlnCys: 0.0 ± 0.0
0.66GlnAsp: 0.66 ± 0.332
2.309GlnGlu: 2.309 ± 1.161
1.979GlnPhe: 1.979 ± 0.995
2.309GlnGly: 2.309 ± 1.763
0.33GlnHis: 0.33 ± 0.166
3.958GlnIle: 3.958 ± 0.503
0.989GlnLys: 0.989 ± 0.498
1.979GlnLeu: 1.979 ± 1.132
0.989GlnMet: 0.989 ± 2.065
0.66GlnAsn: 0.66 ± 0.332
4.947GlnPro: 4.947 ± 1.494
1.649GlnGln: 1.649 ± 2.026
1.649GlnArg: 1.649 ± 0.498
2.968GlnSer: 2.968 ± 2.544
2.968GlnThr: 2.968 ± 0.368
2.968GlnVal: 2.968 ± 1.537
0.0GlnTrp: 0.0 ± 0.0
1.649GlnTyr: 1.649 ± 0.866
0.0GlnXaa: 0.0 ± 0.0
Arg
2.639ArgAla: 2.639 ± 0.965
0.66ArgCys: 0.66 ± 0.332
2.309ArgAsp: 2.309 ± 1.161
2.309ArgGlu: 2.309 ± 2.11
5.277ArgPhe: 5.277 ± 1.197
3.298ArgGly: 3.298 ± 1.731
0.0ArgHis: 0.0 ± 0.0
3.958ArgIle: 3.958 ± 2.265
4.617ArgLys: 4.617 ± 0.168
3.958ArgLeu: 3.958 ± 1.085
0.33ArgMet: 0.33 ± 1.083
3.628ArgAsn: 3.628 ± 1.028
2.639ArgPro: 2.639 ± 1.327
1.319ArgGln: 1.319 ± 0.664
3.298ArgArg: 3.298 ± 1.015
3.298ArgSer: 3.298 ± 1.437
3.298ArgThr: 3.298 ± 2.553
1.979ArgVal: 1.979 ± 2.268
1.319ArgTrp: 1.319 ± 0.664
1.649ArgTyr: 1.649 ± 0.829
0.0ArgXaa: 0.0 ± 0.0
Ser
2.639SerAla: 2.639 ± 0.743
0.0SerCys: 0.0 ± 0.0
5.607SerAsp: 5.607 ± 0.449
5.277SerGlu: 5.277 ± 2.102
6.266SerPhe: 6.266 ± 0.77
5.607SerGly: 5.607 ± 0.449
1.979SerHis: 1.979 ± 0.995
7.256SerIle: 7.256 ± 0.798
5.277SerLys: 5.277 ± 3.57
7.916SerLeu: 7.916 ± 0.198
2.309SerMet: 2.309 ± 0.895
4.947SerAsn: 4.947 ± 0.931
3.298SerPro: 3.298 ± 1.437
2.968SerGln: 2.968 ± 0.991
3.958SerArg: 3.958 ± 2.261
8.905SerSer: 8.905 ± 1.259
5.607SerThr: 5.607 ± 1.216
5.607SerVal: 5.607 ± 0.81
0.33SerTrp: 0.33 ± 0.166
4.617SerTyr: 4.617 ± 0.779
0.0SerXaa: 0.0 ± 0.0
Thr
2.639ThrAla: 2.639 ± 1.08
0.989ThrCys: 0.989 ± 0.498
3.298ThrAsp: 3.298 ± 0.346
2.309ThrGlu: 2.309 ± 1.161
2.639ThrPhe: 2.639 ± 0.743
1.649ThrGly: 1.649 ± 0.829
1.649ThrHis: 1.649 ± 0.866
3.958ThrIle: 3.958 ± 1.085
4.288ThrLys: 4.288 ± 2.119
6.596ThrLeu: 6.596 ± 0.729
1.649ThrMet: 1.649 ± 0.839
1.979ThrAsn: 1.979 ± 0.542
2.309ThrPro: 2.309 ± 2.765
1.649ThrGln: 1.649 ± 0.829
2.968ThrArg: 2.968 ± 1.884
5.937ThrSer: 5.937 ± 2.38
4.617ThrThr: 4.617 ± 2.257
4.288ThrVal: 4.288 ± 2.119
1.319ThrTrp: 1.319 ± 0.86
1.979ThrTyr: 1.979 ± 0.852
0.0ThrXaa: 0.0 ± 0.0
Val
4.288ValAla: 4.288 ± 0.283
1.319ValCys: 1.319 ± 0.664
4.617ValAsp: 4.617 ± 1.694
4.288ValGlu: 4.288 ± 2.904
2.309ValPhe: 2.309 ± 0.629
1.979ValGly: 1.979 ± 0.995
0.66ValHis: 0.66 ± 0.332
3.298ValIle: 3.298 ± 1.165
3.958ValLys: 3.958 ± 3.978
4.617ValLeu: 4.617 ± 2.75
1.649ValMet: 1.649 ± 0.762
3.298ValAsn: 3.298 ± 0.996
5.607ValPro: 5.607 ± 1.245
2.639ValGln: 2.639 ± 1.785
2.309ValArg: 2.309 ± 1.161
8.575ValSer: 8.575 ± 2.104
3.958ValThr: 3.958 ± 0.433
4.617ValVal: 4.617 ± 2.123
0.0ValTrp: 0.0 ± 0.0
0.66ValTyr: 0.66 ± 0.986
0.0ValXaa: 0.0 ± 0.0
Trp
0.33TrpAla: 0.33 ± 0.166
0.33TrpCys: 0.33 ± 0.166
0.33TrpAsp: 0.33 ± 0.166
0.33TrpGlu: 0.33 ± 1.083
0.0TrpPhe: 0.0 ± 0.0
0.33TrpGly: 0.33 ± 0.166
0.33TrpHis: 0.33 ± 0.166
0.66TrpIle: 0.66 ± 0.663
0.33TrpLys: 0.33 ± 0.166
1.649TrpLeu: 1.649 ± 0.829
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.66TrpPro: 0.66 ± 0.332
0.0TrpGln: 0.0 ± 0.0
1.979TrpArg: 1.979 ± 0.852
1.649TrpSer: 1.649 ± 0.839
1.319TrpThr: 1.319 ± 0.664
1.649TrpVal: 1.649 ± 0.829
0.0TrpTrp: 0.0 ± 0.0
1.649TrpTyr: 1.649 ± 0.839
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.628TyrAla: 3.628 ± 1.35
0.66TyrCys: 0.66 ± 0.332
1.979TyrAsp: 1.979 ± 0.852
0.989TyrGlu: 0.989 ± 0.498
2.309TyrPhe: 2.309 ± 1.161
2.309TyrGly: 2.309 ± 0.629
0.33TyrHis: 0.33 ± 0.166
1.649TyrIle: 1.649 ± 0.866
2.968TyrLys: 2.968 ± 1.537
3.298TyrLeu: 3.298 ± 1.659
0.989TyrMet: 0.989 ± 0.498
1.649TyrAsn: 1.649 ± 0.839
1.649TyrPro: 1.649 ± 0.839
2.309TyrGln: 2.309 ± 0.895
2.639TyrArg: 2.639 ± 0.454
2.309TyrSer: 2.309 ± 0.629
2.639TyrThr: 2.639 ± 0.743
2.309TyrVal: 2.309 ± 1.161
0.989TyrTrp: 0.989 ± 0.91
2.968TyrTyr: 2.968 ± 1.537
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.33XaaAsp: 0.33 ± 0.166
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (3033 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski