Human papillomavirus type 54

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Alphapapillomavirus; Alphapapillomavirus 13

Average proteome isoelectric point is 6.71

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A0P0E4X8|A0A0P0E4X8_HPV54 Replication protein E1 OS=Human papillomavirus type 54 OX=1671798 GN=E1 PE=3 SV=1
MM1 pKa = 7.42HH2 pKa = 7.27GNVATIEE9 pKa = 4.75DD10 pKa = 3.98IVLDD14 pKa = 4.33LKK16 pKa = 11.04PEE18 pKa = 4.29PFDD21 pKa = 3.97LYY23 pKa = 10.99CRR25 pKa = 11.84EE26 pKa = 3.97QLEE29 pKa = 4.58DD30 pKa = 4.18SDD32 pKa = 6.06AEE34 pKa = 4.35DD35 pKa = 3.78EE36 pKa = 4.6TAVTQPDD43 pKa = 3.3KK44 pKa = 11.19QAFKK48 pKa = 11.07VLSQCGGVCCKK59 pKa = 8.05TVRR62 pKa = 11.84LCVYY66 pKa = 8.46STHH69 pKa = 5.9TGIRR73 pKa = 11.84VLQEE77 pKa = 4.48LLHH80 pKa = 6.48QDD82 pKa = 3.31ALQIVCPTCASRR94 pKa = 11.84LL95 pKa = 3.75

Molecular weight: 10.57 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A0P0EGW8|A0A0P0EGW8_HPV54 Major capsid protein L1 OS=Human papillomavirus type 54 OX=1671798 GN=L1 PE=3 SV=1
MM1 pKa = 6.89QWVFIIWMQNTKK13 pKa = 10.69CIMWILKK20 pKa = 9.96RR21 pKa = 11.84KK22 pKa = 8.03HH23 pKa = 6.61LSMGNMDD30 pKa = 4.01SGRR33 pKa = 11.84CVWAAASFFLLHH45 pKa = 6.93LYY47 pKa = 9.4LVPKK51 pKa = 9.85RR52 pKa = 11.84HH53 pKa = 5.82CQYY56 pKa = 11.23PLLALLNTPDD66 pKa = 3.46QPIPHH71 pKa = 6.88HH72 pKa = 7.04VPTTPQKK79 pKa = 9.8QSRR82 pKa = 11.84ARR84 pKa = 11.84RR85 pKa = 11.84RR86 pKa = 11.84LEE88 pKa = 3.88NEE90 pKa = 4.22LEE92 pKa = 4.35STAQTSNHH100 pKa = 6.06TAPQTPWAVTTTGTSVTITTRR121 pKa = 11.84TKK123 pKa = 10.76DD124 pKa = 3.18GTQVVVTLHH133 pKa = 6.19LL134 pKa = 4.29

Molecular weight: 15.37 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2370

95

633

338.6

38.04

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.54 ± 0.238

2.785 ± 0.812

5.738 ± 0.527

4.81 ± 0.596

3.629 ± 0.44

5.823 ± 0.456

2.785 ± 0.538

4.895 ± 0.376

4.852 ± 0.73

8.101 ± 0.54

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.278 ± 0.268

4.008 ± 0.584

6.709 ± 1.103

4.937 ± 0.329

5.57 ± 0.209

7.089 ± 0.853

7.722 ± 1.007

6.329 ± 0.31

1.688 ± 0.361

3.713 ± 0.346
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski