Amino acid dipepetide frequency for Hubei picorna-like virus 58

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.203AlaAla: 4.203 ± 0.0
0.701AlaCys: 0.701 ± 0.0
4.203AlaAsp: 4.203 ± 0.0
1.051AlaGlu: 1.051 ± 0.0
3.503AlaPhe: 3.503 ± 0.0
2.452AlaGly: 2.452 ± 0.0
0.0AlaHis: 0.0 ± 0.0
5.604AlaIle: 5.604 ± 0.0
5.604AlaLys: 5.604 ± 0.0
6.305AlaLeu: 6.305 ± 0.0
2.802AlaMet: 2.802 ± 0.0
3.853AlaAsn: 3.853 ± 0.0
2.802AlaPro: 2.802 ± 0.0
1.401AlaGln: 1.401 ± 0.0
3.853AlaArg: 3.853 ± 0.0
4.553AlaSer: 4.553 ± 0.0
3.853AlaThr: 3.853 ± 0.0
2.802AlaVal: 2.802 ± 0.0
1.401AlaTrp: 1.401 ± 0.0
1.051AlaTyr: 1.051 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.701CysAla: 0.701 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.051CysGlu: 1.051 ± 0.0
2.102CysPhe: 2.102 ± 0.0
0.701CysGly: 0.701 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.701CysIle: 0.701 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.051CysLeu: 1.051 ± 0.0
0.701CysMet: 0.701 ± 0.0
0.35CysAsn: 0.35 ± 0.0
1.051CysPro: 1.051 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
2.102CysSer: 2.102 ± 0.0
1.401CysThr: 1.401 ± 0.0
0.701CysVal: 0.701 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.35CysTyr: 0.35 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.152AspAla: 3.152 ± 0.0
0.35AspCys: 0.35 ± 0.0
2.802AspAsp: 2.802 ± 0.0
3.152AspGlu: 3.152 ± 0.0
3.503AspPhe: 3.503 ± 0.0
3.503AspGly: 3.503 ± 0.0
0.0AspHis: 0.0 ± 0.0
3.853AspIle: 3.853 ± 0.0
4.203AspLys: 4.203 ± 0.0
3.853AspLeu: 3.853 ± 0.0
2.102AspMet: 2.102 ± 0.0
2.452AspAsn: 2.452 ± 0.0
3.152AspPro: 3.152 ± 0.0
1.051AspGln: 1.051 ± 0.0
3.152AspArg: 3.152 ± 0.0
3.152AspSer: 3.152 ± 0.0
5.604AspThr: 5.604 ± 0.0
3.503AspVal: 3.503 ± 0.0
0.35AspTrp: 0.35 ± 0.0
2.102AspTyr: 2.102 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
5.604GluAla: 5.604 ± 0.0
0.35GluCys: 0.35 ± 0.0
2.802GluAsp: 2.802 ± 0.0
2.102GluGlu: 2.102 ± 0.0
3.853GluPhe: 3.853 ± 0.0
3.853GluGly: 3.853 ± 0.0
1.051GluHis: 1.051 ± 0.0
2.802GluIle: 2.802 ± 0.0
3.152GluLys: 3.152 ± 0.0
7.356GluLeu: 7.356 ± 0.0
2.102GluMet: 2.102 ± 0.0
3.853GluAsn: 3.853 ± 0.0
1.051GluPro: 1.051 ± 0.0
1.401GluGln: 1.401 ± 0.0
2.452GluArg: 2.452 ± 0.0
2.452GluSer: 2.452 ± 0.0
4.203GluThr: 4.203 ± 0.0
2.102GluVal: 2.102 ± 0.0
0.0GluTrp: 0.0 ± 0.0
2.452GluTyr: 2.452 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.102PheAla: 2.102 ± 0.0
1.051PheCys: 1.051 ± 0.0
3.853PheAsp: 3.853 ± 0.0
2.802PheGlu: 2.802 ± 0.0
2.802PhePhe: 2.802 ± 0.0
3.853PheGly: 3.853 ± 0.0
0.701PheHis: 0.701 ± 0.0
2.102PheIle: 2.102 ± 0.0
3.503PheLys: 3.503 ± 0.0
3.503PheLeu: 3.503 ± 0.0
0.701PheMet: 0.701 ± 0.0
2.802PheAsn: 2.802 ± 0.0
2.452PhePro: 2.452 ± 0.0
2.802PheGln: 2.802 ± 0.0
2.452PheArg: 2.452 ± 0.0
3.853PheSer: 3.853 ± 0.0
2.802PheThr: 2.802 ± 0.0
3.853PheVal: 3.853 ± 0.0
1.051PheTrp: 1.051 ± 0.0
1.401PheTyr: 1.401 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
3.853GlyAla: 3.853 ± 0.0
0.701GlyCys: 0.701 ± 0.0
2.802GlyAsp: 2.802 ± 0.0
1.751GlyGlu: 1.751 ± 0.0
2.802GlyPhe: 2.802 ± 0.0
2.802GlyGly: 2.802 ± 0.0
0.35GlyHis: 0.35 ± 0.0
5.954GlyIle: 5.954 ± 0.0
4.553GlyLys: 4.553 ± 0.0
5.604GlyLeu: 5.604 ± 0.0
2.452GlyMet: 2.452 ± 0.0
4.553GlyAsn: 4.553 ± 0.0
1.051GlyPro: 1.051 ± 0.0
1.401GlyGln: 1.401 ± 0.0
1.751GlyArg: 1.751 ± 0.0
4.904GlySer: 4.904 ± 0.0
4.553GlyThr: 4.553 ± 0.0
3.853GlyVal: 3.853 ± 0.0
0.35GlyTrp: 0.35 ± 0.0
1.751GlyTyr: 1.751 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.35HisAla: 0.35 ± 0.0
0.701HisCys: 0.701 ± 0.0
1.401HisAsp: 1.401 ± 0.0
1.051HisGlu: 1.051 ± 0.0
0.701HisPhe: 0.701 ± 0.0
0.35HisGly: 0.35 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.35HisIle: 0.35 ± 0.0
1.051HisLys: 1.051 ± 0.0
2.102HisLeu: 2.102 ± 0.0
0.35HisMet: 0.35 ± 0.0
0.35HisAsn: 0.35 ± 0.0
0.35HisPro: 0.35 ± 0.0
0.35HisGln: 0.35 ± 0.0
0.701HisArg: 0.701 ± 0.0
0.701HisSer: 0.701 ± 0.0
0.701HisThr: 0.701 ± 0.0
2.102HisVal: 2.102 ± 0.0
0.35HisTrp: 0.35 ± 0.0
0.35HisTyr: 0.35 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.203IleAla: 4.203 ± 0.0
1.051IleCys: 1.051 ± 0.0
2.802IleAsp: 2.802 ± 0.0
3.152IleGlu: 3.152 ± 0.0
2.452IlePhe: 2.452 ± 0.0
4.203IleGly: 4.203 ± 0.0
2.102IleHis: 2.102 ± 0.0
4.203IleIle: 4.203 ± 0.0
6.305IleLys: 6.305 ± 0.0
3.152IleLeu: 3.152 ± 0.0
1.051IleMet: 1.051 ± 0.0
3.853IleAsn: 3.853 ± 0.0
2.452IlePro: 2.452 ± 0.0
1.751IleGln: 1.751 ± 0.0
1.751IleArg: 1.751 ± 0.0
6.305IleSer: 6.305 ± 0.0
7.356IleThr: 7.356 ± 0.0
3.152IleVal: 3.152 ± 0.0
0.0IleTrp: 0.0 ± 0.0
1.751IleTyr: 1.751 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
4.904LysAla: 4.904 ± 0.0
2.102LysCys: 2.102 ± 0.0
3.152LysAsp: 3.152 ± 0.0
5.604LysGlu: 5.604 ± 0.0
3.853LysPhe: 3.853 ± 0.0
2.452LysGly: 2.452 ± 0.0
1.751LysHis: 1.751 ± 0.0
2.802LysIle: 2.802 ± 0.0
3.503LysLys: 3.503 ± 0.0
4.203LysLeu: 4.203 ± 0.0
1.401LysMet: 1.401 ± 0.0
4.553LysAsn: 4.553 ± 0.0
1.401LysPro: 1.401 ± 0.0
3.503LysGln: 3.503 ± 0.0
2.102LysArg: 2.102 ± 0.0
4.904LysSer: 4.904 ± 0.0
4.203LysThr: 4.203 ± 0.0
5.254LysVal: 5.254 ± 0.0
0.0LysTrp: 0.0 ± 0.0
3.853LysTyr: 3.853 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
5.954LeuAla: 5.954 ± 0.0
1.051LeuCys: 1.051 ± 0.0
3.853LeuAsp: 3.853 ± 0.0
3.152LeuGlu: 3.152 ± 0.0
4.203LeuPhe: 4.203 ± 0.0
5.954LeuGly: 5.954 ± 0.0
2.102LeuHis: 2.102 ± 0.0
6.655LeuIle: 6.655 ± 0.0
5.254LeuLys: 5.254 ± 0.0
5.254LeuLeu: 5.254 ± 0.0
2.802LeuMet: 2.802 ± 0.0
6.655LeuAsn: 6.655 ± 0.0
5.254LeuPro: 5.254 ± 0.0
2.802LeuGln: 2.802 ± 0.0
2.802LeuArg: 2.802 ± 0.0
2.452LeuSer: 2.452 ± 0.0
8.757LeuThr: 8.757 ± 0.0
4.553LeuVal: 4.553 ± 0.0
1.051LeuTrp: 1.051 ± 0.0
3.503LeuTyr: 3.503 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
3.853MetAla: 3.853 ± 0.0
0.35MetCys: 0.35 ± 0.0
1.401MetAsp: 1.401 ± 0.0
2.102MetGlu: 2.102 ± 0.0
1.401MetPhe: 1.401 ± 0.0
1.751MetGly: 1.751 ± 0.0
1.051MetHis: 1.051 ± 0.0
0.35MetIle: 0.35 ± 0.0
2.452MetLys: 2.452 ± 0.0
1.751MetLeu: 1.751 ± 0.0
0.35MetMet: 0.35 ± 0.0
0.35MetAsn: 0.35 ± 0.0
1.751MetPro: 1.751 ± 0.0
2.102MetGln: 2.102 ± 0.0
0.701MetArg: 0.701 ± 0.0
2.102MetSer: 2.102 ± 0.0
1.401MetThr: 1.401 ± 0.0
2.102MetVal: 2.102 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.35MetTyr: 0.35 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.853AsnAla: 3.853 ± 0.0
1.401AsnCys: 1.401 ± 0.0
1.401AsnAsp: 1.401 ± 0.0
3.503AsnGlu: 3.503 ± 0.0
2.102AsnPhe: 2.102 ± 0.0
3.152AsnGly: 3.152 ± 0.0
1.401AsnHis: 1.401 ± 0.0
3.853AsnIle: 3.853 ± 0.0
4.203AsnLys: 4.203 ± 0.0
3.853AsnLeu: 3.853 ± 0.0
2.102AsnMet: 2.102 ± 0.0
3.503AsnAsn: 3.503 ± 0.0
5.954AsnPro: 5.954 ± 0.0
3.503AsnGln: 3.503 ± 0.0
2.452AsnArg: 2.452 ± 0.0
3.503AsnSer: 3.503 ± 0.0
3.853AsnThr: 3.853 ± 0.0
2.452AsnVal: 2.452 ± 0.0
1.051AsnTrp: 1.051 ± 0.0
4.203AsnTyr: 4.203 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
1.751ProAla: 1.751 ± 0.0
0.701ProCys: 0.701 ± 0.0
4.203ProAsp: 4.203 ± 0.0
2.802ProGlu: 2.802 ± 0.0
1.401ProPhe: 1.401 ± 0.0
2.802ProGly: 2.802 ± 0.0
0.701ProHis: 0.701 ± 0.0
1.401ProIle: 1.401 ± 0.0
1.751ProLys: 1.751 ± 0.0
4.553ProLeu: 4.553 ± 0.0
0.701ProMet: 0.701 ± 0.0
2.102ProAsn: 2.102 ± 0.0
2.452ProPro: 2.452 ± 0.0
1.401ProGln: 1.401 ± 0.0
1.051ProArg: 1.051 ± 0.0
5.254ProSer: 5.254 ± 0.0
2.802ProThr: 2.802 ± 0.0
4.904ProVal: 4.904 ± 0.0
0.35ProTrp: 0.35 ± 0.0
2.102ProTyr: 2.102 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
2.452GlnAla: 2.452 ± 0.0
0.701GlnCys: 0.701 ± 0.0
1.401GlnAsp: 1.401 ± 0.0
4.553GlnGlu: 4.553 ± 0.0
2.102GlnPhe: 2.102 ± 0.0
2.452GlnGly: 2.452 ± 0.0
0.701GlnHis: 0.701 ± 0.0
2.452GlnIle: 2.452 ± 0.0
1.751GlnLys: 1.751 ± 0.0
4.553GlnLeu: 4.553 ± 0.0
1.051GlnMet: 1.051 ± 0.0
0.35GlnAsn: 0.35 ± 0.0
2.452GlnPro: 2.452 ± 0.0
1.401GlnGln: 1.401 ± 0.0
1.401GlnArg: 1.401 ± 0.0
2.452GlnSer: 2.452 ± 0.0
2.452GlnThr: 2.452 ± 0.0
1.751GlnVal: 1.751 ± 0.0
0.701GlnTrp: 0.701 ± 0.0
0.701GlnTyr: 0.701 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
1.401ArgAla: 1.401 ± 0.0
0.0ArgCys: 0.0 ± 0.0
2.452ArgAsp: 2.452 ± 0.0
2.452ArgGlu: 2.452 ± 0.0
2.452ArgPhe: 2.452 ± 0.0
2.452ArgGly: 2.452 ± 0.0
0.0ArgHis: 0.0 ± 0.0
4.904ArgIle: 4.904 ± 0.0
2.802ArgLys: 2.802 ± 0.0
4.203ArgLeu: 4.203 ± 0.0
1.051ArgMet: 1.051 ± 0.0
2.102ArgAsn: 2.102 ± 0.0
1.051ArgPro: 1.051 ± 0.0
2.452ArgGln: 2.452 ± 0.0
1.751ArgArg: 1.751 ± 0.0
2.452ArgSer: 2.452 ± 0.0
1.751ArgThr: 1.751 ± 0.0
3.853ArgVal: 3.853 ± 0.0
0.35ArgTrp: 0.35 ± 0.0
1.051ArgTyr: 1.051 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
4.203SerAla: 4.203 ± 0.0
0.0SerCys: 0.0 ± 0.0
3.503SerAsp: 3.503 ± 0.0
3.152SerGlu: 3.152 ± 0.0
2.802SerPhe: 2.802 ± 0.0
3.853SerGly: 3.853 ± 0.0
0.701SerHis: 0.701 ± 0.0
5.254SerIle: 5.254 ± 0.0
3.853SerLys: 3.853 ± 0.0
5.604SerLeu: 5.604 ± 0.0
2.452SerMet: 2.452 ± 0.0
7.706SerAsn: 7.706 ± 0.0
4.203SerPro: 4.203 ± 0.0
3.503SerGln: 3.503 ± 0.0
3.152SerArg: 3.152 ± 0.0
6.655SerSer: 6.655 ± 0.0
4.553SerThr: 4.553 ± 0.0
4.553SerVal: 4.553 ± 0.0
0.701SerTrp: 0.701 ± 0.0
2.802SerTyr: 2.802 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
3.152ThrAla: 3.152 ± 0.0
0.35ThrCys: 0.35 ± 0.0
5.604ThrAsp: 5.604 ± 0.0
3.503ThrGlu: 3.503 ± 0.0
3.503ThrPhe: 3.503 ± 0.0
5.604ThrGly: 5.604 ± 0.0
1.051ThrHis: 1.051 ± 0.0
2.102ThrIle: 2.102 ± 0.0
4.203ThrLys: 4.203 ± 0.0
7.005ThrLeu: 7.005 ± 0.0
1.051ThrMet: 1.051 ± 0.0
6.655ThrAsn: 6.655 ± 0.0
3.503ThrPro: 3.503 ± 0.0
3.503ThrGln: 3.503 ± 0.0
2.452ThrArg: 2.452 ± 0.0
4.553ThrSer: 4.553 ± 0.0
8.757ThrThr: 8.757 ± 0.0
7.706ThrVal: 7.706 ± 0.0
0.35ThrTrp: 0.35 ± 0.0
3.853ThrTyr: 3.853 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
4.553ValAla: 4.553 ± 0.0
1.401ValCys: 1.401 ± 0.0
2.802ValAsp: 2.802 ± 0.0
4.553ValGlu: 4.553 ± 0.0
2.102ValPhe: 2.102 ± 0.0
3.503ValGly: 3.503 ± 0.0
0.35ValHis: 0.35 ± 0.0
4.203ValIle: 4.203 ± 0.0
3.853ValLys: 3.853 ± 0.0
5.604ValLeu: 5.604 ± 0.0
1.751ValMet: 1.751 ± 0.0
2.452ValAsn: 2.452 ± 0.0
1.401ValPro: 1.401 ± 0.0
2.802ValGln: 2.802 ± 0.0
3.503ValArg: 3.503 ± 0.0
7.356ValSer: 7.356 ± 0.0
5.604ValThr: 5.604 ± 0.0
4.553ValVal: 4.553 ± 0.0
0.35ValTrp: 0.35 ± 0.0
3.853ValTyr: 3.853 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.701TrpAsp: 0.701 ± 0.0
1.051TrpGlu: 1.051 ± 0.0
0.35TrpPhe: 0.35 ± 0.0
0.35TrpGly: 0.35 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.35TrpLys: 0.35 ± 0.0
0.35TrpLeu: 0.35 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.35TrpAsn: 0.35 ± 0.0
0.35TrpPro: 0.35 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.051TrpArg: 1.051 ± 0.0
1.051TrpSer: 1.051 ± 0.0
0.701TrpThr: 0.701 ± 0.0
1.051TrpVal: 1.051 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.701TrpTyr: 0.701 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.102TyrAla: 2.102 ± 0.0
0.0TyrCys: 0.0 ± 0.0
3.853TyrAsp: 3.853 ± 0.0
2.452TyrGlu: 2.452 ± 0.0
2.452TyrPhe: 2.452 ± 0.0
1.751TyrGly: 1.751 ± 0.0
0.35TyrHis: 0.35 ± 0.0
3.503TyrIle: 3.503 ± 0.0
3.152TyrLys: 3.152 ± 0.0
4.203TyrLeu: 4.203 ± 0.0
0.35TyrMet: 0.35 ± 0.0
2.452TyrAsn: 2.452 ± 0.0
1.051TyrPro: 1.051 ± 0.0
0.701TyrGln: 0.701 ± 0.0
2.452TyrArg: 2.452 ± 0.0
2.452TyrSer: 2.452 ± 0.0
3.152TyrThr: 3.152 ± 0.0
1.751TyrVal: 1.751 ± 0.0
0.0TyrTrp: 0.0 ± 0.0
2.102TyrTyr: 2.102 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (2856 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski