Amino acid dipepetide frequency for Botrytis cinerea RNA virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
16.22AlaAla: 16.22 ± 0.836
0.754AlaCys: 0.754 ± 0.489
5.658AlaAsp: 5.658 ± 1.266
6.413AlaGlu: 6.413 ± 1.764
3.018AlaPhe: 3.018 ± 0.511
7.167AlaGly: 7.167 ± 1.19
3.018AlaHis: 3.018 ± 1.954
6.413AlaIle: 6.413 ± 1.688
4.149AlaLys: 4.149 ± 0.222
12.825AlaLeu: 12.825 ± 3.375
2.263AlaMet: 2.263 ± 0.013
5.658AlaAsn: 5.658 ± 0.213
7.544AlaPro: 7.544 ± 0.538
4.904AlaGln: 4.904 ± 1.755
9.808AlaArg: 9.808 ± 0.058
8.299AlaSer: 8.299 ± 0.444
6.035AlaThr: 6.035 ± 0.95
5.281AlaVal: 5.281 ± 0.524
1.509AlaTrp: 1.509 ± 0.484
6.413AlaTyr: 6.413 ± 0.209
0.0AlaXaa: 0.0 ± 0.0
Cys
1.132CysAla: 1.132 ± 0.733
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.377CysGly: 0.377 ± 0.244
0.0CysHis: 0.0 ± 0.0
1.132CysIle: 1.132 ± 0.24
0.0CysLys: 0.0 ± 0.0
1.132CysLeu: 1.132 ± 0.24
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.377CysSer: 0.377 ± 0.244
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
6.413AspAla: 6.413 ± 0.777
0.0AspCys: 0.0 ± 0.0
2.641AspAsp: 2.641 ± 0.231
0.377AspGlu: 0.377 ± 0.249
3.772AspPhe: 3.772 ± 0.471
1.509AspGly: 1.509 ± 0.502
1.509AspHis: 1.509 ± 0.977
3.018AspIle: 3.018 ± 0.511
2.641AspLys: 2.641 ± 1.217
3.772AspLeu: 3.772 ± 0.022
0.754AspMet: 0.754 ± 0.393
0.754AspAsn: 0.754 ± 0.004
1.509AspPro: 1.509 ± 0.009
0.754AspGln: 0.754 ± 0.497
3.772AspArg: 3.772 ± 1.008
4.149AspSer: 4.149 ± 0.715
1.509AspThr: 1.509 ± 0.502
1.886AspVal: 1.886 ± 0.258
0.0AspTrp: 0.0 ± 0.0
3.018AspTyr: 3.018 ± 1.004
0.0AspXaa: 0.0 ± 0.0
Glu
4.527GluAla: 4.527 ± 0.027
0.377GluCys: 0.377 ± 0.249
1.886GluAsp: 1.886 ± 0.751
2.263GluGlu: 2.263 ± 0.013
1.886GluPhe: 1.886 ± 0.258
2.263GluGly: 2.263 ± 0.48
1.509GluHis: 1.509 ± 0.009
1.886GluIle: 1.886 ± 0.258
1.509GluLys: 1.509 ± 0.484
7.922GluLeu: 7.922 ± 0.2
1.132GluMet: 1.132 ± 0.24
3.018GluAsn: 3.018 ± 1.99
2.641GluPro: 2.641 ± 0.262
2.641GluGln: 2.641 ± 0.231
3.395GluArg: 3.395 ± 0.226
2.641GluSer: 2.641 ± 0.231
2.263GluThr: 2.263 ± 0.48
1.886GluVal: 1.886 ± 0.235
0.0GluTrp: 0.0 ± 0.0
0.754GluTyr: 0.754 ± 0.004
0.0GluXaa: 0.0 ± 0.0
Phe
3.772PheAla: 3.772 ± 0.022
0.0PheCys: 0.0 ± 0.0
1.886PheAsp: 1.886 ± 0.258
2.263PheGlu: 2.263 ± 0.973
1.886PhePhe: 1.886 ± 0.235
2.263PheGly: 2.263 ± 0.506
0.377PheHis: 0.377 ± 0.249
1.132PheIle: 1.132 ± 0.24
0.0PheLys: 0.0 ± 0.0
4.527PheLeu: 4.527 ± 0.027
1.509PheMet: 1.509 ± 0.009
1.886PheAsn: 1.886 ± 0.235
4.149PhePro: 4.149 ± 0.271
1.886PheGln: 1.886 ± 0.258
1.509PheArg: 1.509 ± 0.502
5.658PheSer: 5.658 ± 1.759
3.018PheThr: 3.018 ± 0.968
3.018PheVal: 3.018 ± 0.018
0.377PheTrp: 0.377 ± 0.244
0.754PheTyr: 0.754 ± 0.004
0.0PheXaa: 0.0 ± 0.0
Gly
7.167GlyAla: 7.167 ± 1.19
0.377GlyCys: 0.377 ± 0.244
3.018GlyAsp: 3.018 ± 0.968
2.641GlyGlu: 2.641 ± 0.724
3.772GlyPhe: 3.772 ± 1.457
4.149GlyGly: 4.149 ± 0.715
1.132GlyHis: 1.132 ± 0.253
3.018GlyIle: 3.018 ± 1.004
3.395GlyLys: 3.395 ± 1.212
4.904GlyLeu: 4.904 ± 0.276
1.509GlyMet: 1.509 ± 0.484
1.886GlyAsn: 1.886 ± 0.258
1.886GlyPro: 1.886 ± 0.258
1.509GlyGln: 1.509 ± 0.009
3.395GlyArg: 3.395 ± 0.267
2.641GlySer: 2.641 ± 0.231
2.641GlyThr: 2.641 ± 0.262
2.641GlyVal: 2.641 ± 0.724
0.754GlyTrp: 0.754 ± 0.004
0.754GlyTyr: 0.754 ± 0.489
0.0GlyXaa: 0.0 ± 0.0
His
4.527HisAla: 4.527 ± 0.027
0.0HisCys: 0.0 ± 0.0
1.132HisAsp: 1.132 ± 0.24
1.132HisGlu: 1.132 ± 0.733
2.263HisPhe: 2.263 ± 0.506
2.263HisGly: 2.263 ± 0.48
0.377HisHis: 0.377 ± 0.244
1.132HisIle: 1.132 ± 0.24
1.132HisLys: 1.132 ± 0.733
3.395HisLeu: 3.395 ± 1.212
0.377HisMet: 0.377 ± 0.249
1.132HisAsn: 1.132 ± 0.253
0.377HisPro: 0.377 ± 0.244
0.377HisGln: 0.377 ± 0.249
2.641HisArg: 2.641 ± 0.231
2.641HisSer: 2.641 ± 0.724
1.509HisThr: 1.509 ± 0.484
2.641HisVal: 2.641 ± 0.755
0.0HisTrp: 0.0 ± 0.0
0.754HisTyr: 0.754 ± 0.004
0.0HisXaa: 0.0 ± 0.0
Ile
5.281IleAla: 5.281 ± 0.524
0.754IleCys: 0.754 ± 0.489
1.132IleAsp: 1.132 ± 0.746
2.641IleGlu: 2.641 ± 0.231
0.377IlePhe: 0.377 ± 0.244
1.509IleGly: 1.509 ± 0.484
0.377IleHis: 0.377 ± 0.249
1.132IleIle: 1.132 ± 0.253
1.509IleLys: 1.509 ± 0.009
6.79IleLeu: 6.79 ± 0.533
0.377IleMet: 0.377 ± 0.244
2.641IleAsn: 2.641 ± 0.755
4.149IlePro: 4.149 ± 0.271
1.886IleGln: 1.886 ± 0.235
2.263IleArg: 2.263 ± 1.466
3.018IleSer: 3.018 ± 0.511
2.263IleThr: 2.263 ± 0.48
2.641IleVal: 2.641 ± 0.262
0.0IleTrp: 0.0 ± 0.0
0.754IleTyr: 0.754 ± 0.004
0.0IleXaa: 0.0 ± 0.0
Lys
2.641LysAla: 2.641 ± 0.231
0.0LysCys: 0.0 ± 0.0
0.754LysAsp: 0.754 ± 0.489
2.263LysGlu: 2.263 ± 0.013
0.754LysPhe: 0.754 ± 0.004
1.132LysGly: 1.132 ± 0.733
1.132LysHis: 1.132 ± 0.24
3.018LysIle: 3.018 ± 0.968
0.377LysLys: 0.377 ± 0.249
5.281LysLeu: 5.281 ± 2.434
0.377LysMet: 0.377 ± 0.244
1.509LysAsn: 1.509 ± 0.502
1.509LysPro: 1.509 ± 0.009
1.509LysGln: 1.509 ± 0.009
2.641LysArg: 2.641 ± 0.262
1.509LysSer: 1.509 ± 0.009
4.527LysThr: 4.527 ± 1.452
1.132LysVal: 1.132 ± 0.24
0.754LysTrp: 0.754 ± 0.004
1.509LysTyr: 1.509 ± 0.009
0.0LysXaa: 0.0 ± 0.0
Leu
15.843LeuAla: 15.843 ± 1.878
0.377LeuCys: 0.377 ± 0.244
3.772LeuAsp: 3.772 ± 0.022
4.149LeuGlu: 4.149 ± 0.715
4.149LeuPhe: 4.149 ± 1.208
4.527LeuGly: 4.527 ± 0.466
2.641LeuHis: 2.641 ± 1.217
3.395LeuIle: 3.395 ± 0.226
4.904LeuLys: 4.904 ± 1.204
11.316LeuLeu: 11.316 ± 1.412
1.886LeuMet: 1.886 ± 0.235
4.527LeuAsn: 4.527 ± 1.452
6.79LeuPro: 6.79 ± 1.026
2.641LeuGln: 2.641 ± 0.231
9.053LeuArg: 9.053 ± 0.932
11.694LeuSer: 11.694 ± 0.316
6.79LeuThr: 6.79 ± 0.533
4.149LeuVal: 4.149 ± 0.222
1.509LeuTrp: 1.509 ± 0.502
3.018LeuTyr: 3.018 ± 0.018
0.0LeuXaa: 0.0 ± 0.0
Met
1.132MetAla: 1.132 ± 0.253
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
1.886MetGlu: 1.886 ± 0.728
0.377MetPhe: 0.377 ± 0.244
0.377MetGly: 0.377 ± 0.249
0.754MetHis: 0.754 ± 0.004
0.0MetIle: 0.0 ± 0.0
0.377MetLys: 0.377 ± 0.244
2.641MetLeu: 2.641 ± 0.724
0.754MetMet: 0.754 ± 0.004
0.377MetAsn: 0.377 ± 0.249
0.754MetPro: 0.754 ± 0.489
0.754MetGln: 0.754 ± 0.004
1.132MetArg: 1.132 ± 0.24
2.641MetSer: 2.641 ± 0.262
0.754MetThr: 0.754 ± 0.004
1.509MetVal: 1.509 ± 0.009
0.754MetTrp: 0.754 ± 0.489
1.132MetTyr: 1.132 ± 0.24
0.0MetXaa: 0.0 ± 0.0
Asn
5.658AsnAla: 5.658 ± 0.213
0.0AsnCys: 0.0 ± 0.0
1.886AsnAsp: 1.886 ± 0.235
1.886AsnGlu: 1.886 ± 0.258
1.886AsnPhe: 1.886 ± 0.258
1.886AsnGly: 1.886 ± 0.235
1.509AsnHis: 1.509 ± 0.009
1.509AsnIle: 1.509 ± 0.009
1.132AsnLys: 1.132 ± 0.733
3.772AsnLeu: 3.772 ± 0.022
1.132AsnMet: 1.132 ± 0.183
3.395AsnAsn: 3.395 ± 1.253
1.886AsnPro: 1.886 ± 0.235
0.754AsnGln: 0.754 ± 0.004
2.641AsnArg: 2.641 ± 0.755
4.527AsnSer: 4.527 ± 1.013
2.641AsnThr: 2.641 ± 0.231
3.018AsnVal: 3.018 ± 0.018
0.754AsnTrp: 0.754 ± 0.497
1.886AsnTyr: 1.886 ± 0.235
0.0AsnXaa: 0.0 ± 0.0
Pro
9.808ProAla: 9.808 ± 0.435
0.0ProCys: 0.0 ± 0.0
2.263ProAsp: 2.263 ± 0.013
1.509ProGlu: 1.509 ± 0.502
2.263ProPhe: 2.263 ± 0.999
4.527ProGly: 4.527 ± 0.466
1.886ProHis: 1.886 ± 0.235
3.395ProIle: 3.395 ± 0.267
1.886ProLys: 1.886 ± 0.258
3.772ProLeu: 3.772 ± 1.008
0.377ProMet: 0.377 ± 0.244
0.754ProAsn: 0.754 ± 0.489
3.772ProPro: 3.772 ± 1.501
2.263ProGln: 2.263 ± 0.999
3.772ProArg: 3.772 ± 1.008
6.035ProSer: 6.035 ± 0.529
4.904ProThr: 4.904 ± 2.248
5.658ProVal: 5.658 ± 1.266
0.377ProTrp: 0.377 ± 0.249
1.132ProTyr: 1.132 ± 0.746
0.0ProXaa: 0.0 ± 0.0
Gln
4.527GlnAla: 4.527 ± 0.027
0.377GlnCys: 0.377 ± 0.244
1.509GlnAsp: 1.509 ± 0.502
1.132GlnGlu: 1.132 ± 0.24
1.132GlnPhe: 1.132 ± 0.253
0.754GlnGly: 0.754 ± 0.004
1.886GlnHis: 1.886 ± 0.258
2.263GlnIle: 2.263 ± 0.999
1.509GlnLys: 1.509 ± 0.502
4.904GlnLeu: 4.904 ± 0.769
0.0GlnMet: 0.0 ± 0.0
0.754GlnAsn: 0.754 ± 0.004
2.263GlnPro: 2.263 ± 0.999
1.509GlnGln: 1.509 ± 0.009
2.641GlnArg: 2.641 ± 1.248
1.509GlnSer: 1.509 ± 0.009
1.132GlnThr: 1.132 ± 0.253
4.149GlnVal: 4.149 ± 1.257
0.377GlnTrp: 0.377 ± 0.249
1.132GlnTyr: 1.132 ± 0.733
0.0GlnXaa: 0.0 ± 0.0
Arg
7.167ArgAla: 7.167 ± 1.19
0.0ArgCys: 0.0 ± 0.0
1.886ArgAsp: 1.886 ± 0.728
4.149ArgGlu: 4.149 ± 0.764
1.886ArgPhe: 1.886 ± 0.258
3.018ArgGly: 3.018 ± 0.018
3.772ArgHis: 3.772 ± 0.515
2.263ArgIle: 2.263 ± 0.506
0.754ArgLys: 0.754 ± 0.497
4.149ArgLeu: 4.149 ± 0.715
1.132ArgMet: 1.132 ± 0.24
3.772ArgAsn: 3.772 ± 0.471
2.641ArgPro: 2.641 ± 0.755
3.018ArgGln: 3.018 ± 0.511
4.527ArgArg: 4.527 ± 0.466
5.281ArgSer: 5.281 ± 1.51
3.018ArgThr: 3.018 ± 0.968
4.904ArgVal: 4.904 ± 0.218
1.509ArgTrp: 1.509 ± 0.995
3.018ArgTyr: 3.018 ± 0.511
0.0ArgXaa: 0.0 ± 0.0
Ser
8.676SerAla: 8.676 ± 0.791
0.754SerCys: 0.754 ± 0.004
4.149SerAsp: 4.149 ± 0.764
3.018SerGlu: 3.018 ± 0.475
4.904SerPhe: 4.904 ± 1.262
4.527SerGly: 4.527 ± 0.959
2.263SerHis: 2.263 ± 0.013
3.018SerIle: 3.018 ± 1.004
5.658SerLys: 5.658 ± 0.213
10.185SerLeu: 10.185 ± 0.8
2.641SerMet: 2.641 ± 0.231
3.395SerAsn: 3.395 ± 0.719
6.79SerPro: 6.79 ± 2.012
1.509SerGln: 1.509 ± 0.502
2.263SerArg: 2.263 ± 0.48
4.149SerSer: 4.149 ± 1.75
7.922SerThr: 7.922 ± 0.293
3.772SerVal: 3.772 ± 0.515
1.886SerTrp: 1.886 ± 0.258
4.527SerTyr: 4.527 ± 0.52
0.0SerXaa: 0.0 ± 0.0
Thr
9.43ThrAla: 9.43 ± 0.795
0.0ThrCys: 0.0 ± 0.0
1.886ThrAsp: 1.886 ± 0.235
1.886ThrGlu: 1.886 ± 0.258
3.395ThrPhe: 3.395 ± 0.719
4.527ThrGly: 4.527 ± 0.027
1.509ThrHis: 1.509 ± 0.484
2.263ThrIle: 2.263 ± 0.973
1.132ThrLys: 1.132 ± 0.733
4.904ThrLeu: 4.904 ± 1.204
0.754ThrMet: 0.754 ± 0.004
2.641ThrAsn: 2.641 ± 0.724
3.395ThrPro: 3.395 ± 1.746
3.395ThrGln: 3.395 ± 0.76
2.263ThrArg: 2.263 ± 0.506
4.904ThrSer: 4.904 ± 0.276
6.413ThrThr: 6.413 ± 1.195
3.772ThrVal: 3.772 ± 0.515
1.132ThrTrp: 1.132 ± 0.733
2.641ThrTyr: 2.641 ± 0.724
0.0ThrXaa: 0.0 ± 0.0
Val
4.527ValAla: 4.527 ± 0.027
0.377ValCys: 0.377 ± 0.244
4.527ValAsp: 4.527 ± 0.52
2.641ValGlu: 2.641 ± 1.741
3.018ValPhe: 3.018 ± 0.511
3.772ValGly: 3.772 ± 0.471
3.395ValHis: 3.395 ± 0.267
1.132ValIle: 1.132 ± 0.24
1.509ValLys: 1.509 ± 0.484
6.413ValLeu: 6.413 ± 0.702
0.377ValMet: 0.377 ± 0.244
3.772ValAsn: 3.772 ± 1.008
4.904ValPro: 4.904 ± 1.755
1.886ValGln: 1.886 ± 0.751
2.263ValArg: 2.263 ± 0.013
6.035ValSer: 6.035 ± 0.457
2.641ValThr: 2.641 ± 0.724
3.772ValVal: 3.772 ± 0.471
0.754ValTrp: 0.754 ± 0.497
0.754ValTyr: 0.754 ± 0.004
0.0ValXaa: 0.0 ± 0.0
Trp
0.377TrpAla: 0.377 ± 0.249
0.0TrpCys: 0.0 ± 0.0
1.132TrpAsp: 1.132 ± 0.24
0.754TrpGlu: 0.754 ± 0.497
0.377TrpPhe: 0.377 ± 0.249
0.377TrpGly: 0.377 ± 0.244
0.377TrpHis: 0.377 ± 0.244
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.754TrpLeu: 0.754 ± 0.489
0.377TrpMet: 0.377 ± 0.249
0.754TrpAsn: 0.754 ± 0.497
0.377TrpPro: 0.377 ± 0.249
0.754TrpGln: 0.754 ± 0.497
0.754TrpArg: 0.754 ± 0.004
3.018TrpSer: 3.018 ± 0.511
0.377TrpThr: 0.377 ± 0.249
1.132TrpVal: 1.132 ± 0.24
0.377TrpTrp: 0.377 ± 0.249
0.754TrpTyr: 0.754 ± 0.489
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.527TyrAla: 4.527 ± 2.438
0.0TyrCys: 0.0 ± 0.0
2.641TyrAsp: 2.641 ± 0.231
3.395TyrGlu: 3.395 ± 0.226
0.754TyrPhe: 0.754 ± 0.497
2.263TyrGly: 2.263 ± 0.013
0.377TyrHis: 0.377 ± 0.249
0.377TyrIle: 0.377 ± 0.249
0.754TyrLys: 0.754 ± 0.004
3.772TyrLeu: 3.772 ± 0.022
0.0TyrMet: 0.0 ± 0.0
1.509TyrAsn: 1.509 ± 0.484
3.018TyrPro: 3.018 ± 0.968
1.509TyrGln: 1.509 ± 0.009
1.132TyrArg: 1.132 ± 0.253
5.281TyrSer: 5.281 ± 2.003
1.886TyrThr: 1.886 ± 0.751
1.509TyrVal: 1.509 ± 0.009
0.0TyrTrp: 0.0 ± 0.0
0.754TyrTyr: 0.754 ± 0.497
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2652 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski