Plasmodium falciparum UGT5.1

Taxonomy: cellular organisms; Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania); Plasmodium falciparum

Average proteome isoelectric point is 7.25

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 5904 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|W7JYT6|W7JYT6_PLAFA Uncharacterized protein OS=Plasmodium falciparum UGT5.1 OX=1237627 GN=C923_02547 PE=4 SV=1
MM1 pKa = 7.58EE2 pKa = 6.01EE3 pKa = 3.93IVDD6 pKa = 4.39DD7 pKa = 4.22GMEE10 pKa = 4.32EE11 pKa = 3.7IDD13 pKa = 4.67LNEE16 pKa = 4.22NSDD19 pKa = 4.44FIHH22 pKa = 7.4DD23 pKa = 4.13GNPLGEE29 pKa = 4.28YY30 pKa = 10.96SNMEE34 pKa = 4.0YY35 pKa = 10.9EE36 pKa = 4.48LLNEE40 pKa = 4.48VSASTDD46 pKa = 3.38FSDD49 pKa = 3.5YY50 pKa = 11.01HH51 pKa = 7.75SVVDD55 pKa = 3.89EE56 pKa = 4.68DD57 pKa = 5.63LINFNDD63 pKa = 3.99DD64 pKa = 3.11VTLEE68 pKa = 4.2TQSMIAHH75 pKa = 6.92GGSLSEE81 pKa = 4.27IEE83 pKa = 4.17EE84 pKa = 4.39TGDD87 pKa = 3.66LSSDD91 pKa = 3.24VDD93 pKa = 3.74RR94 pKa = 11.84LLSSIEE100 pKa = 3.84TTPRR104 pKa = 11.84DD105 pKa = 3.48DD106 pKa = 3.26VVYY109 pKa = 10.56IRR111 pKa = 11.84GDD113 pKa = 3.33IILGEE118 pKa = 4.14DD119 pKa = 3.84EE120 pKa = 5.19IIIEE124 pKa = 4.18NGEE127 pKa = 4.12IILNNTDD134 pKa = 3.64EE135 pKa = 4.7LFEE138 pKa = 5.13DD139 pKa = 4.03VPEE142 pKa = 4.08MLEE145 pKa = 4.01NANLLEE151 pKa = 4.49DD152 pKa = 3.8RR153 pKa = 11.84EE154 pKa = 4.66HH155 pKa = 7.44VFEE158 pKa = 4.42YY159 pKa = 10.54NISVANEE166 pKa = 3.48NTTNQNSYY174 pKa = 10.71NFNAPQDD181 pKa = 4.02NTLTNYY187 pKa = 10.32NISRR191 pKa = 11.84FLQRR195 pKa = 11.84YY196 pKa = 6.69GTTTPNTQHH205 pKa = 6.75NISIHH210 pKa = 6.53RR211 pKa = 11.84DD212 pKa = 3.18GHH214 pKa = 5.2SLRR217 pKa = 11.84SDD219 pKa = 3.19TNIYY223 pKa = 10.86DD224 pKa = 4.61RR225 pKa = 11.84INGPSIRR232 pKa = 11.84EE233 pKa = 3.67NSLYY237 pKa = 10.28PGSFEE242 pKa = 3.77MAQYY246 pKa = 11.03ADD248 pKa = 4.72RR249 pKa = 11.84YY250 pKa = 10.15QMGHH254 pKa = 6.64TIAEE258 pKa = 4.43GFLYY262 pKa = 10.73

Molecular weight: 29.85 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|W7K5D7|W7K5D7_PLAFA Uncharacterized protein OS=Plasmodium falciparum UGT5.1 OX=1237627 GN=C923_00101 PE=3 SV=1
MM1 pKa = 7.39LVNLGPMLVKK11 pKa = 10.76LGPKK15 pKa = 9.81LVIIRR20 pKa = 11.84PISVNLRR27 pKa = 11.84PKK29 pKa = 10.07LVKK32 pKa = 10.38LGPMLVKK39 pKa = 10.39LRR41 pKa = 11.84PMLAKK46 pKa = 10.42LRR48 pKa = 11.84PKK50 pKa = 10.44LVMLGPIFAKK60 pKa = 10.35LRR62 pKa = 11.84PTLVTLRR69 pKa = 11.84PKK71 pKa = 10.75LVMLGPKK78 pKa = 9.91LVTLRR83 pKa = 11.84PTLVTLRR90 pKa = 11.84PTLVTLRR97 pKa = 11.84PTLVTLRR104 pKa = 11.84PKK106 pKa = 10.74YY107 pKa = 11.22VMLGPILLTYY117 pKa = 10.45RR118 pKa = 11.84PILVLVKK125 pKa = 10.34LRR127 pKa = 11.84PVLVKK132 pKa = 10.08VRR134 pKa = 11.84PISVNVRR141 pKa = 11.84PKK143 pKa = 10.83LLVKK147 pKa = 10.55LRR149 pKa = 11.84PKK151 pKa = 9.91LVKK154 pKa = 10.11VRR156 pKa = 11.84PILLKK161 pKa = 10.47VRR163 pKa = 11.84PISVKK168 pKa = 10.1IKK170 pKa = 10.15PKK172 pKa = 10.1SKK174 pKa = 9.77LVKK177 pKa = 9.69VRR179 pKa = 11.84PMLSKK184 pKa = 10.64LRR186 pKa = 11.84SKK188 pKa = 10.28LVKK191 pKa = 10.12VRR193 pKa = 11.84PKK195 pKa = 10.24LVKK198 pKa = 10.06VRR200 pKa = 11.84PKK202 pKa = 10.79LLVTLRR208 pKa = 11.84PMLVKK213 pKa = 10.57LRR215 pKa = 11.84AKK217 pKa = 9.86LVKK220 pKa = 9.84LRR222 pKa = 11.84PMLVKK227 pKa = 10.28VRR229 pKa = 11.84PYY231 pKa = 10.27LVKK234 pKa = 10.61LRR236 pKa = 11.84PLLVNVRR243 pKa = 11.84HH244 pKa = 6.28KK245 pKa = 10.58LVKK248 pKa = 10.13VRR250 pKa = 11.84PP251 pKa = 3.81

Molecular weight: 28.7 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

5865

39

5904

3939455

12

10314

667.3

78.74

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

1.96 ± 0.024

1.798 ± 0.018

6.388 ± 0.028

6.979 ± 0.039

4.399 ± 0.024

2.82 ± 0.031

2.427 ± 0.013

9.308 ± 0.039

11.738 ± 0.037

7.622 ± 0.031

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.212 ± 0.015

14.436 ± 0.095

1.957 ± 0.02

2.766 ± 0.014

2.652 ± 0.017

6.404 ± 0.024

4.11 ± 0.018

3.759 ± 0.023

0.502 ± 0.009

5.763 ± 0.027
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski