Plasmodium falciparum MaliPS096_E11

Taxonomy: cellular organisms; Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania); Plasmodium falciparum

Average proteome isoelectric point is 7.27

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 6301 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A024WTS0|A0A024WTS0_PLAFA Uncharacterized protein OS=Plasmodium falciparum MaliPS096_E11 OX=1036727 GN=PFMALIP_01815 PE=4 SV=1
MM1 pKa = 7.67IIFKK5 pKa = 10.23RR6 pKa = 11.84YY7 pKa = 10.07HH8 pKa = 5.89NIKK11 pKa = 10.4NNNCISFSDD20 pKa = 3.93YY21 pKa = 10.72EE22 pKa = 4.08RR23 pKa = 11.84SIKK26 pKa = 10.51NFSISSHH33 pKa = 6.56AEE35 pKa = 3.52NNYY38 pKa = 10.85DD39 pKa = 4.96NIINEE44 pKa = 4.05YY45 pKa = 10.83KK46 pKa = 10.35KK47 pKa = 10.82IKK49 pKa = 10.25DD50 pKa = 3.18INNNINILSSVHH62 pKa = 5.32RR63 pKa = 11.84KK64 pKa = 9.39GRR66 pKa = 11.84ILYY69 pKa = 10.44DD70 pKa = 3.23SFLEE74 pKa = 4.26INKK77 pKa = 9.96LEE79 pKa = 3.98NDD81 pKa = 3.44KK82 pKa = 11.25KK83 pKa = 10.63EE84 pKa = 3.95KK85 pKa = 10.29HH86 pKa = 5.8EE87 pKa = 5.03KK88 pKa = 9.08EE89 pKa = 5.05DD90 pKa = 3.63EE91 pKa = 4.3YY92 pKa = 11.41EE93 pKa = 4.79DD94 pKa = 3.75NDD96 pKa = 3.54EE97 pKa = 4.82SFLEE101 pKa = 4.27TEE103 pKa = 4.36EE104 pKa = 5.43YY105 pKa = 10.63EE106 pKa = 5.04DD107 pKa = 3.65NDD109 pKa = 3.4EE110 pKa = 4.88SFLEE114 pKa = 4.27TEE116 pKa = 4.31EE117 pKa = 4.96YY118 pKa = 10.67EE119 pKa = 4.38DD120 pKa = 5.87NEE122 pKa = 4.17DD123 pKa = 3.12EE124 pKa = 5.44KK125 pKa = 11.7YY126 pKa = 11.23NKK128 pKa = 10.66DD129 pKa = 3.3EE130 pKa = 4.73DD131 pKa = 4.72DD132 pKa = 3.82YY133 pKa = 12.03AEE135 pKa = 4.56SFIEE139 pKa = 3.89TDD141 pKa = 3.16EE142 pKa = 4.8YY143 pKa = 11.26EE144 pKa = 4.63DD145 pKa = 5.45NEE147 pKa = 4.08DD148 pKa = 3.71DD149 pKa = 5.58KK150 pKa = 11.96YY151 pKa = 11.9NKK153 pKa = 10.66DD154 pKa = 3.3EE155 pKa = 4.87DD156 pKa = 4.61DD157 pKa = 3.87YY158 pKa = 11.83SEE160 pKa = 5.04SFIEE164 pKa = 3.93TDD166 pKa = 3.1EE167 pKa = 4.55YY168 pKa = 11.52DD169 pKa = 3.9DD170 pKa = 5.5NEE172 pKa = 4.04EE173 pKa = 3.73EE174 pKa = 4.76QYY176 pKa = 11.76NKK178 pKa = 11.05DD179 pKa = 3.38EE180 pKa = 5.19DD181 pKa = 4.78DD182 pKa = 4.05YY183 pKa = 11.83ADD185 pKa = 4.26SFIEE189 pKa = 3.97TDD191 pKa = 3.06HH192 pKa = 7.24YY193 pKa = 11.51EE194 pKa = 4.24NNDD197 pKa = 3.55DD198 pKa = 3.99KK199 pKa = 11.85NEE201 pKa = 3.94EE202 pKa = 3.99EE203 pKa = 4.99EE204 pKa = 4.86EE205 pKa = 4.67YY206 pKa = 11.24NDD208 pKa = 3.48QDD210 pKa = 3.52NDD212 pKa = 3.23YY213 pKa = 10.63GYY215 pKa = 11.45NFLEE219 pKa = 4.06TDD221 pKa = 3.53EE222 pKa = 5.23YY223 pKa = 11.47DD224 pKa = 3.88DD225 pKa = 4.98SEE227 pKa = 4.85EE228 pKa = 3.89YY229 pKa = 10.55DD230 pKa = 3.93YY231 pKa = 11.81DD232 pKa = 3.85DD233 pKa = 4.63KK234 pKa = 11.76EE235 pKa = 4.35YY236 pKa = 11.54GEE238 pKa = 4.57SFLEE242 pKa = 4.63KK243 pKa = 10.98EE244 pKa = 4.55EE245 pKa = 4.74DD246 pKa = 3.7DD247 pKa = 4.18EE248 pKa = 5.6AAMTAEE254 pKa = 3.98EE255 pKa = 4.57LVEE258 pKa = 4.21LEE260 pKa = 3.97NTEE263 pKa = 4.55DD264 pKa = 3.71VNTPTMVEE272 pKa = 4.08TEE274 pKa = 4.75EE275 pKa = 4.58IDD277 pKa = 3.94SDD279 pKa = 4.02EE280 pKa = 4.7NGNKK284 pKa = 9.75SSSSISYY291 pKa = 9.29ISSIVFLMVTLLYY304 pKa = 10.86FMNN307 pKa = 4.61

Molecular weight: 36.95 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A024WV09|A0A024WV09_PLAFA Uncharacterized protein OS=Plasmodium falciparum MaliPS096_E11 OX=1036727 GN=PFMALIP_01150 PE=3 SV=1
MM1 pKa = 7.61VIRR4 pKa = 11.84EE5 pKa = 4.44SVSRR9 pKa = 11.84IYY11 pKa = 10.84VGNLPSHH18 pKa = 6.2VSSRR22 pKa = 11.84DD23 pKa = 3.23VEE25 pKa = 4.32NEE27 pKa = 3.08FRR29 pKa = 11.84KK30 pKa = 10.51YY31 pKa = 11.3GNILKK36 pKa = 10.22CDD38 pKa = 3.51VKK40 pKa = 10.59KK41 pKa = 9.2TVSGAAFAFIEE52 pKa = 4.59FEE54 pKa = 4.33DD55 pKa = 4.29ARR57 pKa = 11.84DD58 pKa = 3.3AADD61 pKa = 4.76AIKK64 pKa = 10.62EE65 pKa = 3.83KK66 pKa = 10.72DD67 pKa = 3.39GCDD70 pKa = 3.44FEE72 pKa = 5.57GNKK75 pKa = 10.04LRR77 pKa = 11.84VEE79 pKa = 4.49VPFNARR85 pKa = 11.84EE86 pKa = 3.83NGRR89 pKa = 11.84YY90 pKa = 7.71NARR93 pKa = 11.84GGGRR97 pKa = 11.84GMMHH101 pKa = 7.62RR102 pKa = 11.84GPKK105 pKa = 9.07SRR107 pKa = 11.84RR108 pKa = 11.84GRR110 pKa = 11.84YY111 pKa = 7.77VVEE114 pKa = 4.12VTGLPISGSWQDD126 pKa = 3.96LKK128 pKa = 11.61DD129 pKa = 3.59HH130 pKa = 6.28LRR132 pKa = 11.84EE133 pKa = 4.28AGEE136 pKa = 4.55CGHH139 pKa = 7.27ADD141 pKa = 3.39VFKK144 pKa = 10.97DD145 pKa = 3.4GTGEE149 pKa = 3.83VSFFNKK155 pKa = 10.15DD156 pKa = 3.38DD157 pKa = 3.63MLEE160 pKa = 4.66AIDD163 pKa = 4.88KK164 pKa = 10.54FNGSIFRR171 pKa = 11.84SHH173 pKa = 6.72EE174 pKa = 4.13GEE176 pKa = 3.77KK177 pKa = 10.71SKK179 pKa = 10.98ISIRR183 pKa = 11.84QKK185 pKa = 8.21KK186 pKa = 5.84TLWRR190 pKa = 11.84RR191 pKa = 11.84DD192 pKa = 3.2DD193 pKa = 3.74GGYY196 pKa = 10.49GRR198 pKa = 11.84YY199 pKa = 9.35NSRR202 pKa = 11.84HH203 pKa = 5.55RR204 pKa = 11.84SYY206 pKa = 11.42SSRR209 pKa = 11.84SYY211 pKa = 10.69SRR213 pKa = 11.84SGKK216 pKa = 9.73RR217 pKa = 11.84SYY219 pKa = 9.89TRR221 pKa = 11.84SRR223 pKa = 11.84SRR225 pKa = 11.84SYY227 pKa = 11.08SSRR230 pKa = 11.84SYY232 pKa = 10.75SRR234 pKa = 11.84SRR236 pKa = 11.84SSSSRR241 pKa = 11.84SRR243 pKa = 11.84SRR245 pKa = 11.84SMDD248 pKa = 3.04RR249 pKa = 11.84RR250 pKa = 11.84RR251 pKa = 11.84DD252 pKa = 3.43TYY254 pKa = 11.14DD255 pKa = 2.76KK256 pKa = 10.51KK257 pKa = 10.76RR258 pKa = 11.84SYY260 pKa = 10.91SRR262 pKa = 11.84SLSYY266 pKa = 9.54QEE268 pKa = 3.97RR269 pKa = 11.84RR270 pKa = 11.84RR271 pKa = 11.84NNRR274 pKa = 11.84TISKK278 pKa = 9.6SRR280 pKa = 11.84SRR282 pKa = 11.84SRR284 pKa = 11.84TNSRR288 pKa = 11.84SSSWSHH294 pKa = 5.94KK295 pKa = 9.54RR296 pKa = 11.84RR297 pKa = 11.84HH298 pKa = 5.26

Molecular weight: 34.56 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

6244

57

6301

3932225

10

10148

624.1

73.67

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

1.966 ± 0.022

1.828 ± 0.016

6.304 ± 0.03

6.936 ± 0.043

4.472 ± 0.028

2.822 ± 0.027

2.407 ± 0.015

9.336 ± 0.044

11.767 ± 0.038

7.672 ± 0.032

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.214 ± 0.013

14.319 ± 0.085

1.973 ± 0.019

2.755 ± 0.015

2.675 ± 0.018

6.389 ± 0.024

4.109 ± 0.019

3.751 ± 0.02

0.518 ± 0.009

5.789 ± 0.029
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski