Amino acid dipepetide frequency for Furculomyces boomerangus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	2.94AlaAla: 2.94 ± 0.047	0.618AlaCys: 0.618 ± 0.015	2.28AlaAsp: 2.28 ± 0.03	2.887AlaGlu: 2.887 ± 0.037	2.088AlaPhe: 2.088 ± 0.03	2.527AlaGly: 2.527 ± 0.037	0.887AlaHis: 0.887 ± 0.018	3.686AlaIle: 3.686 ± 0.036	3.578AlaLys: 3.578 ± 0.041	4.565AlaLeu: 4.565 ± 0.049	1.067AlaMet: 1.067 ± 0.023	2.8AlaAsn: 2.8 ± 0.033	1.783AlaPro: 1.783 ± 0.03	1.772AlaGln: 1.772 ± 0.03	1.99AlaArg: 1.99 ± 0.029	4.344AlaSer: 4.344 ± 0.048	2.733AlaThr: 2.733 ± 0.036	2.789AlaVal: 2.789 ± 0.038	0.393AlaTrp: 0.393 ± 0.013	1.507AlaTyr: 1.507 ± 0.023	0.0AlaXaa: 0.0 ± 0.0
Cys	0.511CysAla: 0.511 ± 0.015	0.219CysCys: 0.219 ± 0.009	0.607CysAsp: 0.607 ± 0.017	0.664CysGlu: 0.664 ± 0.018	0.63CysPhe: 0.63 ± 0.015	0.846CysGly: 0.846 ± 0.018	0.235CysHis: 0.235 ± 0.01	0.898CysIle: 0.898 ± 0.018	0.816CysLys: 0.816 ± 0.021	1.162CysLeu: 1.162 ± 0.023	0.268CysMet: 0.268 ± 0.01	0.637CysAsn: 0.637 ± 0.015	0.508CysPro: 0.508 ± 0.014	0.317CysGln: 0.317 ± 0.011	0.449CysArg: 0.449 ± 0.013	1.009CysSer: 1.009 ± 0.02	0.688CysThr: 0.688 ± 0.019	0.72CysVal: 0.72 ± 0.017	0.127CysTrp: 0.127 ± 0.006	0.431CysTyr: 0.431 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	2.187AspAla: 2.187 ± 0.031	0.612AspCys: 0.612 ± 0.015	2.83AspAsp: 2.83 ± 0.037	3.691AspGlu: 3.691 ± 0.042	2.773AspPhe: 2.773 ± 0.03	2.703AspGly: 2.703 ± 0.037	0.986AspHis: 0.986 ± 0.03	4.688AspIle: 4.688 ± 0.04	3.558AspLys: 3.558 ± 0.036	4.92AspLeu: 4.92 ± 0.038	1.166AspMet: 1.166 ± 0.023	3.232AspAsn: 3.232 ± 0.033	2.296AspPro: 2.296 ± 0.032	1.987AspGln: 1.987 ± 0.028	1.757AspArg: 1.757 ± 0.025	5.655AspSer: 5.655 ± 0.055	3.233AspThr: 3.233 ± 0.035	2.831AspVal: 2.831 ± 0.031	0.474AspTrp: 0.474 ± 0.013	2.045AspTyr: 2.045 ± 0.027	0.0AspXaa: 0.0 ± 0.0
Glu	2.92GluAla: 2.92 ± 0.039	0.706GluCys: 0.706 ± 0.016	3.204GluAsp: 3.204 ± 0.038	4.483GluGlu: 4.483 ± 0.067	2.76GluPhe: 2.76 ± 0.03	2.385GluGly: 2.385 ± 0.029	1.227GluHis: 1.227 ± 0.021	5.176GluIle: 5.176 ± 0.047	6.294GluLys: 6.294 ± 0.054	5.634GluLeu: 5.634 ± 0.059	1.532GluMet: 1.532 ± 0.024	5.992GluAsn: 5.992 ± 0.058	2.162GluPro: 2.162 ± 0.042	2.336GluGln: 2.336 ± 0.03	2.458GluArg: 2.458 ± 0.031	5.972GluSer: 5.972 ± 0.057	4.118GluThr: 4.118 ± 0.042	2.577GluVal: 2.577 ± 0.032	0.593GluTrp: 0.593 ± 0.015	2.598GluTyr: 2.598 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	2.083PheAla: 2.083 ± 0.03	0.644PheCys: 0.644 ± 0.014	2.895PheAsp: 2.895 ± 0.035	2.986PheGlu: 2.986 ± 0.032	1.912PhePhe: 1.912 ± 0.029	3.235PheGly: 3.235 ± 0.04	0.765PheHis: 0.765 ± 0.015	2.888PheIle: 2.888 ± 0.035	2.863PheLys: 2.863 ± 0.032	3.71PheLeu: 3.71 ± 0.039	0.963PheMet: 0.963 ± 0.017	2.552PheAsn: 2.552 ± 0.027	1.688PhePro: 1.688 ± 0.024	1.435PheGln: 1.435 ± 0.021	1.532PheArg: 1.532 ± 0.024	4.466PheSer: 4.466 ± 0.042	2.249PheThr: 2.249 ± 0.027	2.682PheVal: 2.682 ± 0.034	0.455PheTrp: 0.455 ± 0.013	1.657PheTyr: 1.657 ± 0.023	0.0PheXaa: 0.0 ± 0.0
Gly	2.592GlyAla: 2.592 ± 0.046	0.692GlyCys: 0.692 ± 0.018	2.527GlyAsp: 2.527 ± 0.031	2.63GlyGlu: 2.63 ± 0.04	2.714GlyPhe: 2.714 ± 0.036	3.436GlyGly: 3.436 ± 0.061	1.052GlyHis: 1.052 ± 0.021	4.198GlyIle: 4.198 ± 0.033	3.945GlyLys: 3.945 ± 0.04	4.571GlyLeu: 4.571 ± 0.039	1.222GlyMet: 1.222 ± 0.025	3.684GlyAsn: 3.684 ± 0.041	1.586GlyPro: 1.586 ± 0.027	1.527GlyGln: 1.527 ± 0.029	2.056GlyArg: 2.056 ± 0.034	4.977GlySer: 4.977 ± 0.052	2.954GlyThr: 2.954 ± 0.037	3.096GlyVal: 3.096 ± 0.043	0.573GlyTrp: 0.573 ± 0.017	2.316GlyTyr: 2.316 ± 0.03	0.0GlyXaa: 0.0 ± 0.0
His	0.807HisAla: 0.807 ± 0.018	0.232HisCys: 0.232 ± 0.008	0.835HisAsp: 0.835 ± 0.017	1.076HisGlu: 1.076 ± 0.018	0.878HisPhe: 0.878 ± 0.016	1.03HisGly: 1.03 ± 0.02	0.48HisHis: 0.48 ± 0.016	1.349HisIle: 1.349 ± 0.024	1.519HisLys: 1.519 ± 0.027	1.764HisLeu: 1.764 ± 0.027	0.38HisMet: 0.38 ± 0.01	1.23HisAsn: 1.23 ± 0.021	1.071HisPro: 1.071 ± 0.02	0.804HisGln: 0.804 ± 0.017	0.807HisArg: 0.807 ± 0.02	1.864HisSer: 1.864 ± 0.028	1.063HisThr: 1.063 ± 0.017	0.964HisVal: 0.964 ± 0.017	0.166HisTrp: 0.166 ± 0.007	0.661HisTyr: 0.661 ± 0.014	0.0HisXaa: 0.0 ± 0.0
Ile	3.397IleAla: 3.397 ± 0.04	0.913IleCys: 0.913 ± 0.02	4.343IleAsp: 4.343 ± 0.037	4.794IleGlu: 4.794 ± 0.045	3.002IlePhe: 3.002 ± 0.035	3.648IleGly: 3.648 ± 0.042	1.509IleHis: 1.509 ± 0.021	4.464IleIle: 4.464 ± 0.045	5.594IleLys: 5.594 ± 0.056	6.32IleLeu: 6.32 ± 0.05	1.305IleMet: 1.305 ± 0.023	5.192IleAsn: 5.192 ± 0.052	3.719IlePro: 3.719 ± 0.034	2.869IleGln: 2.869 ± 0.033	2.691IleArg: 2.691 ± 0.031	7.446IleSer: 7.446 ± 0.058	3.626IleThr: 3.626 ± 0.035	3.95IleVal: 3.95 ± 0.038	0.57IleTrp: 0.57 ± 0.015	2.443IleTyr: 2.443 ± 0.027	0.0IleXaa: 0.0 ± 0.0
Lys	3.608LysAla: 3.608 ± 0.044	0.805LysCys: 0.805 ± 0.024	4.079LysAsp: 4.079 ± 0.037	5.051LysGlu: 5.051 ± 0.05	2.645LysPhe: 2.645 ± 0.026	3.038LysGly: 3.038 ± 0.031	1.698LysHis: 1.698 ± 0.029	5.633LysIle: 5.633 ± 0.053	7.513LysLys: 7.513 ± 0.092	6.949LysLeu: 6.949 ± 0.051	1.676LysMet: 1.676 ± 0.022	6.892LysAsn: 6.892 ± 0.064	3.495LysPro: 3.495 ± 0.046	3.028LysGln: 3.028 ± 0.033	3.513LysArg: 3.513 ± 0.037	7.429LysSer: 7.429 ± 0.071	5.239LysThr: 5.239 ± 0.052	3.914LysVal: 3.914 ± 0.039	0.608LysTrp: 0.608 ± 0.014	2.923LysTyr: 2.923 ± 0.033	0.0LysXaa: 0.0 ± 0.0
Leu	4.75LeuAla: 4.75 ± 0.048	1.142LeuCys: 1.142 ± 0.02	5.234LeuAsp: 5.234 ± 0.047	6.619LeuGlu: 6.619 ± 0.059	3.943LeuPhe: 3.943 ± 0.041	4.937LeuGly: 4.937 ± 0.049	1.496LeuHis: 1.496 ± 0.021	5.439LeuIle: 5.439 ± 0.052	6.655LeuLys: 6.655 ± 0.054	8.131LeuLeu: 8.131 ± 0.065	1.834LeuMet: 1.834 ± 0.025	5.624LeuAsn: 5.624 ± 0.045	3.733LeuPro: 3.733 ± 0.043	3.186LeuGln: 3.186 ± 0.034	3.36LeuArg: 3.36 ± 0.038	8.301LeuSer: 8.301 ± 0.062	4.098LeuThr: 4.098 ± 0.04	5.679LeuVal: 5.679 ± 0.052	0.804LeuTrp: 0.804 ± 0.019	3.057LeuTyr: 3.057 ± 0.036	0.0LeuXaa: 0.0 ± 0.0
Met	1.239MetAla: 1.239 ± 0.022	0.261MetCys: 0.261 ± 0.008	1.341MetAsp: 1.341 ± 0.019	1.451MetGlu: 1.451 ± 0.021	1.033MetPhe: 1.033 ± 0.021	1.175MetGly: 1.175 ± 0.022	0.361MetHis: 0.361 ± 0.011	1.426MetIle: 1.426 ± 0.021	1.461MetLys: 1.461 ± 0.019	1.834MetLeu: 1.834 ± 0.025	0.506MetMet: 0.506 ± 0.014	1.511MetAsn: 1.511 ± 0.023	0.752MetPro: 0.752 ± 0.016	0.678MetGln: 0.678 ± 0.014	0.8MetArg: 0.8 ± 0.015	1.721MetSer: 1.721 ± 0.025	0.99MetThr: 0.99 ± 0.018	1.26MetVal: 1.26 ± 0.022	0.186MetTrp: 0.186 ± 0.007	0.771MetTyr: 0.771 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	2.747AsnAla: 2.747 ± 0.035	0.689AsnCys: 0.689 ± 0.017	3.654AsnAsp: 3.654 ± 0.039	4.566AsnGlu: 4.566 ± 0.045	2.892AsnPhe: 2.892 ± 0.033	3.554AsnGly: 3.554 ± 0.036	1.433AsnHis: 1.433 ± 0.022	5.558AsnIle: 5.558 ± 0.052	5.557AsnLys: 5.557 ± 0.06	6.077AsnLeu: 6.077 ± 0.053	1.541AsnMet: 1.541 ± 0.022	6.032AsnAsn: 6.032 ± 0.078	3.483AsnPro: 3.483 ± 0.04	3.358AsnGln: 3.358 ± 0.042	2.636AsnArg: 2.636 ± 0.034	7.691AsnSer: 7.691 ± 0.076	4.859AsnThr: 4.859 ± 0.052	3.492AsnVal: 3.492 ± 0.035	0.534AsnTrp: 0.534 ± 0.011	2.558AsnTyr: 2.558 ± 0.028	0.0AsnXaa: 0.0 ± 0.0
Pro	1.853ProAla: 1.853 ± 0.03	0.352ProCys: 0.352 ± 0.015	2.095ProAsp: 2.095 ± 0.032	3.276ProGlu: 3.276 ± 0.031	1.652ProPhe: 1.652 ± 0.026	2.119ProGly: 2.119 ± 0.035	0.764ProHis: 0.764 ± 0.017	3.049ProIle: 3.049 ± 0.034	3.666ProLys: 3.666 ± 0.049	3.376ProLeu: 3.376 ± 0.037	0.704ProMet: 0.704 ± 0.015	3.237ProAsn: 3.237 ± 0.037	2.117ProPro: 2.117 ± 0.044	1.868ProGln: 1.868 ± 0.035	1.551ProArg: 1.551 ± 0.025	4.036ProSer: 4.036 ± 0.056	2.971ProThr: 2.971 ± 0.049	2.464ProVal: 2.464 ± 0.04	0.305ProTrp: 0.305 ± 0.01	1.266ProTyr: 1.266 ± 0.022	0.0ProXaa: 0.0 ± 0.0
Gln	1.794GlnAla: 1.794 ± 0.029	0.349GlnCys: 0.349 ± 0.011	1.72GlnAsp: 1.72 ± 0.024	2.351GlnGlu: 2.351 ± 0.028	1.38GlnPhe: 1.38 ± 0.019	1.501GlnGly: 1.501 ± 0.028	0.722GlnHis: 0.722 ± 0.017	2.793GlnIle: 2.793 ± 0.03	3.396GlnLys: 3.396 ± 0.035	3.224GlnLeu: 3.224 ± 0.04	0.834GlnMet: 0.834 ± 0.019	3.595GlnAsn: 3.595 ± 0.052	1.573GlnPro: 1.573 ± 0.027	1.857GlnGln: 1.857 ± 0.043	1.529GlnArg: 1.529 ± 0.026	3.297GlnSer: 3.297 ± 0.032	2.596GlnThr: 2.596 ± 0.037	1.931GlnVal: 1.931 ± 0.03	0.283GlnTrp: 0.283 ± 0.01	1.244GlnTyr: 1.244 ± 0.023	0.0GlnXaa: 0.0 ± 0.0
Arg	1.954ArgAla: 1.954 ± 0.029	0.422ArgCys: 0.422 ± 0.012	1.991ArgAsp: 1.991 ± 0.032	2.24ArgGlu: 2.24 ± 0.031	1.843ArgPhe: 1.843 ± 0.023	1.908ArgGly: 1.908 ± 0.036	0.797ArgHis: 0.797 ± 0.021	2.986ArgIle: 2.986 ± 0.032	3.435ArgLys: 3.435 ± 0.036	3.419ArgLeu: 3.419 ± 0.039	0.895ArgMet: 0.895 ± 0.018	2.993ArgAsn: 2.993 ± 0.03	1.357ArgPro: 1.357 ± 0.028	1.361ArgGln: 1.361 ± 0.02	1.947ArgArg: 1.947 ± 0.031	3.285ArgSer: 3.285 ± 0.046	2.016ArgThr: 2.016 ± 0.025	2.189ArgVal: 2.189 ± 0.027	0.38ArgTrp: 0.38 ± 0.013	1.434ArgTyr: 1.434 ± 0.024	0.0ArgXaa: 0.0 ± 0.0
Ser	4.322SerAla: 4.322 ± 0.043	0.949SerCys: 0.949 ± 0.024	5.194SerAsp: 5.194 ± 0.055	6.236SerGlu: 6.236 ± 0.059	4.273SerPhe: 4.273 ± 0.043	5.45SerGly: 5.45 ± 0.06	1.67SerHis: 1.67 ± 0.025	6.892SerIle: 6.892 ± 0.059	7.969SerLys: 7.969 ± 0.067	8.284SerLeu: 8.284 ± 0.067	1.808SerMet: 1.808 ± 0.022	7.04SerAsn: 7.04 ± 0.074	3.976SerPro: 3.976 ± 0.056	3.687SerGln: 3.687 ± 0.04	3.753SerArg: 3.753 ± 0.045	10.954SerSer: 10.954 ± 0.187	6.094SerThr: 6.094 ± 0.08	5.236SerVal: 5.236 ± 0.053	0.723SerTrp: 0.723 ± 0.015	2.885SerTyr: 2.885 ± 0.039	0.0SerXaa: 0.0 ± 0.0
Thr	2.624ThrAla: 2.624 ± 0.032	0.676ThrCys: 0.676 ± 0.018	3.019ThrAsp: 3.019 ± 0.036	3.762ThrGlu: 3.762 ± 0.035	2.5ThrPhe: 2.5 ± 0.031	3.064ThrGly: 3.064 ± 0.037	1.049ThrHis: 1.049 ± 0.022	4.146ThrIle: 4.146 ± 0.043	5.038ThrLys: 5.038 ± 0.044	4.893ThrLeu: 4.893 ± 0.049	1.009ThrMet: 1.009 ± 0.018	4.481ThrAsn: 4.481 ± 0.047	3.081ThrPro: 3.081 ± 0.042	2.363ThrGln: 2.363 ± 0.027	2.283ThrArg: 2.283 ± 0.027	5.613ThrSer: 5.613 ± 0.069	3.825ThrThr: 3.825 ± 0.068	3.11ThrVal: 3.11 ± 0.042	0.445ThrTrp: 0.445 ± 0.013	1.493ThrTyr: 1.493 ± 0.024	0.0ThrXaa: 0.0 ± 0.0
Val	2.921ValAla: 2.921 ± 0.039	0.846ValCys: 0.846 ± 0.017	3.44ValAsp: 3.44 ± 0.035	3.742ValGlu: 3.742 ± 0.059	2.616ValPhe: 2.616 ± 0.033	3.182ValGly: 3.182 ± 0.044	1.034ValHis: 1.034 ± 0.019	3.425ValIle: 3.425 ± 0.04	3.509ValLys: 3.509 ± 0.032	5.163ValLeu: 5.163 ± 0.048	1.062ValMet: 1.062 ± 0.02	3.121ValAsn: 3.121 ± 0.035	2.531ValPro: 2.531 ± 0.036	1.873ValGln: 1.873 ± 0.024	1.975ValArg: 1.975 ± 0.025	5.211ValSer: 5.211 ± 0.044	2.605ValThr: 2.605 ± 0.037	3.728ValVal: 3.728 ± 0.063	0.551ValTrp: 0.551 ± 0.014	2.219ValTyr: 2.219 ± 0.031	0.0ValXaa: 0.0 ± 0.0
Trp	0.487TrpAla: 0.487 ± 0.014	0.13TrpCys: 0.13 ± 0.006	0.543TrpAsp: 0.543 ± 0.013	0.537TrpGlu: 0.537 ± 0.015	0.424TrpPhe: 0.424 ± 0.011	0.447TrpGly: 0.447 ± 0.013	0.157TrpHis: 0.157 ± 0.007	0.699TrpIle: 0.699 ± 0.015	0.662TrpLys: 0.662 ± 0.015	0.778TrpLeu: 0.778 ± 0.017	0.197TrpMet: 0.197 ± 0.008	0.567TrpAsn: 0.567 ± 0.013	0.263TrpPro: 0.263 ± 0.009	0.248TrpGln: 0.248 ± 0.009	0.39TrpArg: 0.39 ± 0.011	0.703TrpSer: 0.703 ± 0.016	0.45TrpThr: 0.45 ± 0.014	0.534TrpVal: 0.534 ± 0.013	0.141TrpTrp: 0.141 ± 0.006	0.291TrpTyr: 0.291 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.498TyrAla: 1.498 ± 0.024	0.487TyrCys: 0.487 ± 0.014	1.793TyrAsp: 1.793 ± 0.026	2.085TyrGlu: 2.085 ± 0.025	1.703TyrPhe: 1.703 ± 0.027	2.165TyrGly: 2.165 ± 0.032	0.66TyrHis: 0.66 ± 0.016	2.404TyrIle: 2.404 ± 0.03	2.706TyrLys: 2.706 ± 0.031	3.25TyrLeu: 3.25 ± 0.04	0.784TyrMet: 0.784 ± 0.014	2.495TyrAsn: 2.495 ± 0.032	1.546TyrPro: 1.546 ± 0.03	1.413TyrGln: 1.413 ± 0.023	1.377TyrArg: 1.377 ± 0.025	3.421TyrSer: 3.421 ± 0.036	2.067TyrThr: 2.067 ± 0.027	1.608TyrVal: 1.608 ± 0.023	0.336TyrTrp: 0.336 ± 0.011	1.46TyrTyr: 1.46 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 6645 proteins (3304190 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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