Amino acid dipepetide frequency for Tepidicaulis marinus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.006AlaAla: 17.006 ± 0.192	1.036AlaCys: 1.036 ± 0.038	6.287AlaAsp: 6.287 ± 0.081	8.718AlaGlu: 8.718 ± 0.109	4.61AlaPhe: 4.61 ± 0.071	11.237AlaGly: 11.237 ± 0.111	2.542AlaHis: 2.542 ± 0.055	5.429AlaIle: 5.429 ± 0.072	4.892AlaLys: 4.892 ± 0.082	14.065AlaLeu: 14.065 ± 0.16	3.334AlaMet: 3.334 ± 0.065	2.776AlaAsn: 2.776 ± 0.056	6.011AlaPro: 6.011 ± 0.095	4.01AlaGln: 4.01 ± 0.07	8.804AlaArg: 8.804 ± 0.093	6.016AlaSer: 6.016 ± 0.084	4.381AlaThr: 4.381 ± 0.064	7.982AlaVal: 7.982 ± 0.099	1.371AlaTrp: 1.371 ± 0.036	2.815AlaTyr: 2.815 ± 0.056	0.0AlaXaa: 0.0 ± 0.0
Cys	1.003CysAla: 1.003 ± 0.036	0.111CysCys: 0.111 ± 0.01	0.501CysAsp: 0.501 ± 0.022	0.512CysGlu: 0.512 ± 0.023	0.317CysPhe: 0.317 ± 0.02	0.808CysGly: 0.808 ± 0.033	0.227CysHis: 0.227 ± 0.016	0.329CysIle: 0.329 ± 0.018	0.244CysLys: 0.244 ± 0.017	0.8CysLeu: 0.8 ± 0.031	0.158CysMet: 0.158 ± 0.012	0.201CysAsn: 0.201 ± 0.014	0.451CysPro: 0.451 ± 0.019	0.225CysGln: 0.225 ± 0.017	0.523CysArg: 0.523 ± 0.025	0.378CysSer: 0.378 ± 0.024	0.424CysThr: 0.424 ± 0.022	0.514CysVal: 0.514 ± 0.024	0.096CysTrp: 0.096 ± 0.01	0.171CysTyr: 0.171 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	6.145AspAla: 6.145 ± 0.089	0.421AspCys: 0.421 ± 0.021	2.49AspAsp: 2.49 ± 0.06	4.132AspGlu: 4.132 ± 0.076	2.204AspPhe: 2.204 ± 0.045	4.923AspGly: 4.923 ± 0.075	1.141AspHis: 1.141 ± 0.034	3.4AspIle: 3.4 ± 0.055	2.183AspLys: 2.183 ± 0.057	5.531AspLeu: 5.531 ± 0.071	1.6AspMet: 1.6 ± 0.042	1.198AspAsn: 1.198 ± 0.037	3.204AspPro: 3.204 ± 0.056	1.418AspGln: 1.418 ± 0.037	3.217AspArg: 3.217 ± 0.059	1.828AspSer: 1.828 ± 0.046	2.598AspThr: 2.598 ± 0.054	3.945AspVal: 3.945 ± 0.062	0.987AspTrp: 0.987 ± 0.029	1.601AspTyr: 1.601 ± 0.038	0.0AspXaa: 0.0 ± 0.0
Glu	9.735GluAla: 9.735 ± 0.105	0.39GluCys: 0.39 ± 0.018	3.617GluAsp: 3.617 ± 0.057	6.355GluGlu: 6.355 ± 0.086	1.935GluPhe: 1.935 ± 0.046	6.028GluGly: 6.028 ± 0.084	1.234GluHis: 1.234 ± 0.035	4.017GluIle: 4.017 ± 0.063	3.913GluLys: 3.913 ± 0.067	6.118GluLeu: 6.118 ± 0.08	1.868GluMet: 1.868 ± 0.049	2.198GluAsn: 2.198 ± 0.043	2.975GluPro: 2.975 ± 0.059	2.162GluGln: 2.162 ± 0.049	5.341GluArg: 5.341 ± 0.089	2.758GluSer: 2.758 ± 0.059	4.258GluThr: 4.258 ± 0.072	4.347GluVal: 4.347 ± 0.073	0.741GluTrp: 0.741 ± 0.027	1.195GluTyr: 1.195 ± 0.038	0.0GluXaa: 0.0 ± 0.0
Phe	4.498PheAla: 4.498 ± 0.076	0.416PheCys: 0.416 ± 0.021	2.494PheAsp: 2.494 ± 0.042	2.571PheGlu: 2.571 ± 0.053	1.7PhePhe: 1.7 ± 0.047	3.477PheGly: 3.477 ± 0.055	0.766PheHis: 0.766 ± 0.028	1.863PheIle: 1.863 ± 0.039	1.367PheLys: 1.367 ± 0.04	3.757PheLeu: 3.757 ± 0.068	0.947PheMet: 0.947 ± 0.029	1.076PheAsn: 1.076 ± 0.032	1.536PhePro: 1.536 ± 0.044	1.023PheGln: 1.023 ± 0.032	2.016PheArg: 2.016 ± 0.041	2.355PheSer: 2.355 ± 0.048	2.212PheThr: 2.212 ± 0.044	2.445PheVal: 2.445 ± 0.052	0.583PheTrp: 0.583 ± 0.026	1.013PheTyr: 1.013 ± 0.032	0.0PheXaa: 0.0 ± 0.0
Gly	10.169GlyAla: 10.169 ± 0.098	0.742GlyCys: 0.742 ± 0.028	4.383GlyAsp: 4.383 ± 0.077	6.146GlyGlu: 6.146 ± 0.085	3.73GlyPhe: 3.73 ± 0.06	7.566GlyGly: 7.566 ± 0.124	1.823GlyHis: 1.823 ± 0.045	4.645GlyIle: 4.645 ± 0.072	4.092GlyLys: 4.092 ± 0.075	9.054GlyLeu: 9.054 ± 0.1	2.323GlyMet: 2.323 ± 0.054	2.245GlyAsn: 2.245 ± 0.049	3.721GlyPro: 3.721 ± 0.06	2.776GlyGln: 2.776 ± 0.048	5.579GlyArg: 5.579 ± 0.08	4.163GlySer: 4.163 ± 0.066	4.893GlyThr: 4.893 ± 0.078	5.495GlyVal: 5.495 ± 0.077	1.287GlyTrp: 1.287 ± 0.039	2.252GlyTyr: 2.252 ± 0.048	0.0GlyXaa: 0.0 ± 0.0
His	2.192HisAla: 2.192 ± 0.051	0.221HisCys: 0.221 ± 0.018	1.035HisAsp: 1.035 ± 0.036	1.303HisGlu: 1.303 ± 0.039	0.929HisPhe: 0.929 ± 0.03	1.932HisGly: 1.932 ± 0.046	0.55HisHis: 0.55 ± 0.026	1.099HisIle: 1.099 ± 0.029	0.717HisLys: 0.717 ± 0.028	2.195HisLeu: 2.195 ± 0.05	0.568HisMet: 0.568 ± 0.023	0.5HisAsn: 0.5 ± 0.021	1.266HisPro: 1.266 ± 0.034	0.566HisGln: 0.566 ± 0.021	1.189HisArg: 1.189 ± 0.036	0.894HisSer: 0.894 ± 0.03	0.819HisThr: 0.819 ± 0.032	1.478HisVal: 1.478 ± 0.037	0.341HisTrp: 0.341 ± 0.017	0.64HisTyr: 0.64 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	6.764IleAla: 6.764 ± 0.088	0.515IleCys: 0.515 ± 0.02	3.463IleAsp: 3.463 ± 0.067	4.137IleGlu: 4.137 ± 0.061	1.84IlePhe: 1.84 ± 0.05	4.82IleGly: 4.82 ± 0.078	0.941IleHis: 0.941 ± 0.031	2.371IleIle: 2.371 ± 0.053	1.774IleLys: 1.774 ± 0.048	4.299IleLeu: 4.299 ± 0.073	1.09IleMet: 1.09 ± 0.031	1.37IleAsn: 1.37 ± 0.032	2.11IlePro: 2.11 ± 0.053	1.192IleGln: 1.192 ± 0.033	2.979IleArg: 2.979 ± 0.06	2.867IleSer: 2.867 ± 0.059	2.679IleThr: 2.679 ± 0.046	3.717IleVal: 3.717 ± 0.067	0.656IleTrp: 0.656 ± 0.026	1.228IleTyr: 1.228 ± 0.031	0.0IleXaa: 0.0 ± 0.0
Lys	5.488LysAla: 5.488 ± 0.084	0.187LysCys: 0.187 ± 0.012	2.4LysAsp: 2.4 ± 0.055	3.087LysGlu: 3.087 ± 0.057	1.024LysPhe: 1.024 ± 0.03	3.45LysGly: 3.45 ± 0.069	0.727LysHis: 0.727 ± 0.027	2.033LysIle: 2.033 ± 0.044	2.288LysLys: 2.288 ± 0.082	3.979LysLeu: 3.979 ± 0.065	0.906LysMet: 0.906 ± 0.03	1.116LysAsn: 1.116 ± 0.037	2.295LysPro: 2.295 ± 0.054	1.118LysGln: 1.118 ± 0.032	2.895LysArg: 2.895 ± 0.062	2.1LysSer: 2.1 ± 0.049	2.366LysThr: 2.366 ± 0.061	2.829LysVal: 2.829 ± 0.062	0.438LysTrp: 0.438 ± 0.022	0.786LysTyr: 0.786 ± 0.032	0.0LysXaa: 0.0 ± 0.0
Leu	12.989LeuAla: 12.989 ± 0.149	0.906LeuCys: 0.906 ± 0.03	5.663LeuAsp: 5.663 ± 0.084	6.502LeuGlu: 6.502 ± 0.093	3.853LeuPhe: 3.853 ± 0.073	8.403LeuGly: 8.403 ± 0.093	1.962LeuHis: 1.962 ± 0.048	5.313LeuIle: 5.313 ± 0.082	4.499LeuLys: 4.499 ± 0.067	9.299LeuLeu: 9.299 ± 0.127	2.529LeuMet: 2.529 ± 0.052	2.711LeuAsn: 2.711 ± 0.062	5.531LeuPro: 5.531 ± 0.085	2.786LeuGln: 2.786 ± 0.052	6.16LeuArg: 6.16 ± 0.077	6.826LeuSer: 6.826 ± 0.089	5.751LeuThr: 5.751 ± 0.078	6.428LeuVal: 6.428 ± 0.086	1.207LeuTrp: 1.207 ± 0.038	2.333LeuTyr: 2.333 ± 0.048	0.0LeuXaa: 0.0 ± 0.0
Met	3.198MetAla: 3.198 ± 0.06	0.19MetCys: 0.19 ± 0.014	1.293MetAsp: 1.293 ± 0.037	1.623MetGlu: 1.623 ± 0.043	0.676MetPhe: 0.676 ± 0.025	2.095MetGly: 2.095 ± 0.051	0.426MetHis: 0.426 ± 0.02	1.254MetIle: 1.254 ± 0.04	1.185MetLys: 1.185 ± 0.031	2.311MetLeu: 2.311 ± 0.045	0.718MetMet: 0.718 ± 0.027	0.825MetAsn: 0.825 ± 0.03	1.493MetPro: 1.493 ± 0.037	0.841MetGln: 0.841 ± 0.03	1.818MetArg: 1.818 ± 0.034	1.877MetSer: 1.877 ± 0.042	1.657MetThr: 1.657 ± 0.037	1.525MetVal: 1.525 ± 0.044	0.224MetTrp: 0.224 ± 0.017	0.324MetTyr: 0.324 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	3.081AsnAla: 3.081 ± 0.06	0.227AsnCys: 0.227 ± 0.014	1.296AsnAsp: 1.296 ± 0.033	1.644AsnGlu: 1.644 ± 0.035	0.971AsnPhe: 0.971 ± 0.033	2.436AsnGly: 2.436 ± 0.049	0.483AsnHis: 0.483 ± 0.023	1.504AsnIle: 1.504 ± 0.044	0.834AsnLys: 0.834 ± 0.026	2.615AsnLeu: 2.615 ± 0.049	0.713AsnMet: 0.713 ± 0.031	0.692AsnAsn: 0.692 ± 0.025	1.751AsnPro: 1.751 ± 0.045	0.733AsnGln: 0.733 ± 0.029	1.724AsnArg: 1.724 ± 0.042	1.17AsnSer: 1.17 ± 0.038	1.217AsnThr: 1.217 ± 0.036	2.005AsnVal: 2.005 ± 0.049	0.443AsnTrp: 0.443 ± 0.022	0.692AsnTyr: 0.692 ± 0.028	0.0AsnXaa: 0.0 ± 0.0
Pro	6.369ProAla: 6.369 ± 0.107	0.32ProCys: 0.32 ± 0.018	3.325ProAsp: 3.325 ± 0.06	4.466ProGlu: 4.466 ± 0.069	2.051ProPhe: 2.051 ± 0.041	4.627ProGly: 4.627 ± 0.073	1.096ProHis: 1.096 ± 0.034	2.048ProIle: 2.048 ± 0.046	1.875ProLys: 1.875 ± 0.053	5.11ProLeu: 5.11 ± 0.068	1.063ProMet: 1.063 ± 0.034	1.24ProAsn: 1.24 ± 0.037	2.364ProPro: 2.364 ± 0.063	1.688ProGln: 1.688 ± 0.043	2.737ProArg: 2.737 ± 0.057	2.559ProSer: 2.559 ± 0.05	1.746ProThr: 1.746 ± 0.052	3.963ProVal: 3.963 ± 0.059	0.62ProTrp: 0.62 ± 0.029	1.31ProTyr: 1.31 ± 0.038	0.0ProXaa: 0.0 ± 0.0
Gln	3.787GlnAla: 3.787 ± 0.063	0.167GlnCys: 0.167 ± 0.013	1.529GlnAsp: 1.529 ± 0.043	2.08GlnGlu: 2.08 ± 0.042	0.951GlnPhe: 0.951 ± 0.028	2.534GlnGly: 2.534 ± 0.044	0.614GlnHis: 0.614 ± 0.026	1.765GlnIle: 1.765 ± 0.045	1.427GlnLys: 1.427 ± 0.033	2.87GlnLeu: 2.87 ± 0.05	0.913GlnMet: 0.913 ± 0.03	0.966GlnAsn: 0.966 ± 0.032	1.398GlnPro: 1.398 ± 0.037	0.958GlnGln: 0.958 ± 0.032	2.108GlnArg: 2.108 ± 0.05	1.753GlnSer: 1.753 ± 0.044	1.606GlnThr: 1.606 ± 0.047	2.184GlnVal: 2.184 ± 0.048	0.305GlnTrp: 0.305 ± 0.019	0.594GlnTyr: 0.594 ± 0.027	0.0GlnXaa: 0.0 ± 0.0
Arg	7.881ArgAla: 7.881 ± 0.087	0.44ArgCys: 0.44 ± 0.022	3.264ArgAsp: 3.264 ± 0.057	4.652ArgGlu: 4.652 ± 0.071	2.885ArgPhe: 2.885 ± 0.054	4.418ArgGly: 4.418 ± 0.067	1.548ArgHis: 1.548 ± 0.038	3.532ArgIle: 3.532 ± 0.055	2.638ArgLys: 2.638 ± 0.053	7.617ArgLeu: 7.617 ± 0.089	1.74ArgMet: 1.74 ± 0.038	1.599ArgAsn: 1.599 ± 0.04	3.209ArgPro: 3.209 ± 0.067	2.466ArgGln: 2.466 ± 0.053	4.915ArgArg: 4.915 ± 0.085	2.994ArgSer: 2.994 ± 0.054	2.962ArgThr: 2.962 ± 0.052	4.183ArgVal: 4.183 ± 0.064	0.883ArgTrp: 0.883 ± 0.029	1.683ArgTyr: 1.683 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	6.264SerAla: 6.264 ± 0.081	0.365SerCys: 0.365 ± 0.02	2.832SerAsp: 2.832 ± 0.057	3.373SerGlu: 3.373 ± 0.063	2.299SerPhe: 2.299 ± 0.052	5.337SerGly: 5.337 ± 0.094	1.047SerHis: 1.047 ± 0.03	2.439SerIle: 2.439 ± 0.047	1.737SerLys: 1.737 ± 0.045	5.266SerLeu: 5.266 ± 0.084	1.303SerMet: 1.303 ± 0.04	1.257SerAsn: 1.257 ± 0.035	2.647SerPro: 2.647 ± 0.053	1.654SerGln: 1.654 ± 0.041	3.205SerArg: 3.205 ± 0.063	2.748SerSer: 2.748 ± 0.054	2.2SerThr: 2.2 ± 0.045	3.555SerVal: 3.555 ± 0.057	0.726SerTrp: 0.726 ± 0.027	1.421SerTyr: 1.421 ± 0.038	0.0SerXaa: 0.0 ± 0.0
Thr	5.779ThrAla: 5.779 ± 0.081	0.45ThrCys: 0.45 ± 0.023	2.551ThrAsp: 2.551 ± 0.052	2.816ThrGlu: 2.816 ± 0.05	1.975ThrPhe: 1.975 ± 0.041	5.329ThrGly: 5.329 ± 0.079	1.084ThrHis: 1.084 ± 0.036	2.354ThrIle: 2.354 ± 0.047	1.617ThrLys: 1.617 ± 0.037	5.471ThrLeu: 5.471 ± 0.077	1.076ThrMet: 1.076 ± 0.03	1.261ThrAsn: 1.261 ± 0.031	3.071ThrPro: 3.071 ± 0.055	1.544ThrGln: 1.544 ± 0.04	3.209ThrArg: 3.209 ± 0.052	2.53ThrSer: 2.53 ± 0.062	2.001ThrThr: 2.001 ± 0.054	3.715ThrVal: 3.715 ± 0.067	0.586ThrTrp: 0.586 ± 0.024	1.317ThrTyr: 1.317 ± 0.036	0.0ThrXaa: 0.0 ± 0.0
Val	7.054ValAla: 7.054 ± 0.097	0.534ValCys: 0.534 ± 0.021	3.58ValAsp: 3.58 ± 0.058	4.567ValGlu: 4.567 ± 0.076	2.627ValPhe: 2.627 ± 0.059	4.599ValGly: 4.599 ± 0.075	1.356ValHis: 1.356 ± 0.036	3.793ValIle: 3.793 ± 0.07	2.807ValLys: 2.807 ± 0.055	7.227ValLeu: 7.227 ± 0.092	1.769ValMet: 1.769 ± 0.039	2.034ValAsn: 2.034 ± 0.052	3.851ValPro: 3.851 ± 0.065	1.975ValGln: 1.975 ± 0.043	4.317ValArg: 4.317 ± 0.068	4.066ValSer: 4.066 ± 0.067	4.206ValThr: 4.206 ± 0.069	4.411ValVal: 4.411 ± 0.088	0.822ValTrp: 0.822 ± 0.03	1.53ValTyr: 1.53 ± 0.042	0.0ValXaa: 0.0 ± 0.0
Trp	1.34TrpAla: 1.34 ± 0.039	0.117TrpCys: 0.117 ± 0.01	0.656TrpAsp: 0.656 ± 0.025	0.706TrpGlu: 0.706 ± 0.027	0.472TrpPhe: 0.472 ± 0.022	0.921TrpGly: 0.921 ± 0.031	0.345TrpHis: 0.345 ± 0.018	0.558TrpIle: 0.558 ± 0.021	0.511TrpLys: 0.511 ± 0.022	1.635TrpLeu: 1.635 ± 0.042	0.352TrpMet: 0.352 ± 0.018	0.397TrpAsn: 0.397 ± 0.017	0.686TrpPro: 0.686 ± 0.029	0.613TrpGln: 0.613 ± 0.026	1.042TrpArg: 1.042 ± 0.035	0.648TrpSer: 0.648 ± 0.026	0.665TrpThr: 0.665 ± 0.028	0.788TrpVal: 0.788 ± 0.033	0.219TrpTrp: 0.219 ± 0.016	0.283TrpTyr: 0.283 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.579TyrAla: 2.579 ± 0.059	0.238TyrCys: 0.238 ± 0.017	1.507TyrAsp: 1.507 ± 0.042	1.794TyrGlu: 1.794 ± 0.042	1.067TyrPhe: 1.067 ± 0.033	2.146TyrGly: 2.146 ± 0.051	0.523TyrHis: 0.523 ± 0.023	1.064TyrIle: 1.064 ± 0.037	0.912TyrLys: 0.912 ± 0.038	2.433TyrLeu: 2.433 ± 0.049	0.583TyrMet: 0.583 ± 0.021	0.566TyrAsn: 0.566 ± 0.025	1.012TyrPro: 1.012 ± 0.032	0.762TyrGln: 0.762 ± 0.027	1.731TyrArg: 1.731 ± 0.042	1.146TyrSer: 1.146 ± 0.033	1.092TyrThr: 1.092 ± 0.035	1.615TyrVal: 1.615 ± 0.04	0.417TyrTrp: 0.417 ± 0.021	0.664TyrTyr: 0.664 ± 0.029	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3398 proteins (1037151 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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