Amino acid dipepetide frequency for Colletotrichum trifolii

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.2AlaAla: 11.2 ± 0.079	1.138AlaCys: 1.138 ± 0.015	4.879AlaAsp: 4.879 ± 0.033	5.585AlaGlu: 5.585 ± 0.048	3.324AlaPhe: 3.324 ± 0.028	6.659AlaGly: 6.659 ± 0.045	1.855AlaHis: 1.855 ± 0.02	4.157AlaIle: 4.157 ± 0.034	4.261AlaLys: 4.261 ± 0.035	7.98AlaLeu: 7.98 ± 0.05	2.155AlaMet: 2.155 ± 0.023	3.164AlaAsn: 3.164 ± 0.024	5.425AlaPro: 5.425 ± 0.054	3.491AlaGln: 3.491 ± 0.032	5.292AlaArg: 5.292 ± 0.031	7.779AlaSer: 7.779 ± 0.044	5.659AlaThr: 5.659 ± 0.043	6.318AlaVal: 6.318 ± 0.036	1.316AlaTrp: 1.316 ± 0.018	2.249AlaTyr: 2.249 ± 0.024	0.0AlaXaa: 0.0 ± 0.0
Cys	0.99CysAla: 0.99 ± 0.016	0.26CysCys: 0.26 ± 0.008	0.667CysAsp: 0.667 ± 0.01	0.582CysGlu: 0.582 ± 0.011	0.531CysPhe: 0.531 ± 0.009	1.007CysGly: 1.007 ± 0.016	0.326CysHis: 0.326 ± 0.008	0.638CysIle: 0.638 ± 0.012	0.501CysLys: 0.501 ± 0.01	1.191CysLeu: 1.191 ± 0.018	0.269CysMet: 0.269 ± 0.008	0.443CysAsn: 0.443 ± 0.009	0.665CysPro: 0.665 ± 0.013	0.413CysGln: 0.413 ± 0.01	0.76CysArg: 0.76 ± 0.013	0.868CysSer: 0.868 ± 0.014	0.678CysThr: 0.678 ± 0.012	0.841CysVal: 0.841 ± 0.013	0.228CysTrp: 0.228 ± 0.007	0.337CysTyr: 0.337 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	5.384AspAla: 5.384 ± 0.034	0.639AspCys: 0.639 ± 0.012	4.727AspAsp: 4.727 ± 0.048	4.607AspGlu: 4.607 ± 0.04	2.362AspPhe: 2.362 ± 0.024	4.515AspGly: 4.515 ± 0.033	1.23AspHis: 1.23 ± 0.018	2.723AspIle: 2.723 ± 0.022	2.467AspLys: 2.467 ± 0.024	4.931AspLeu: 4.931 ± 0.034	1.327AspMet: 1.327 ± 0.017	1.86AspAsn: 1.86 ± 0.019	3.301AspPro: 3.301 ± 0.027	1.717AspGln: 1.717 ± 0.02	3.098AspArg: 3.098 ± 0.03	3.812AspSer: 3.812 ± 0.033	2.809AspThr: 2.809 ± 0.026	4.194AspVal: 4.194 ± 0.03	0.921AspTrp: 0.921 ± 0.012	1.555AspTyr: 1.555 ± 0.016	0.0AspXaa: 0.0 ± 0.0
Glu	5.767GluAla: 5.767 ± 0.049	0.571GluCys: 0.571 ± 0.011	4.147GluAsp: 4.147 ± 0.037	5.141GluGlu: 5.141 ± 0.059	1.871GluPhe: 1.871 ± 0.019	3.727GluGly: 3.727 ± 0.025	1.364GluHis: 1.364 ± 0.018	2.644GluIle: 2.644 ± 0.022	3.562GluLys: 3.562 ± 0.03	4.956GluLeu: 4.956 ± 0.036	1.424GluMet: 1.424 ± 0.014	2.06GluAsn: 2.06 ± 0.02	2.948GluPro: 2.948 ± 0.04	2.298GluGln: 2.298 ± 0.026	3.851GluArg: 3.851 ± 0.031	4.056GluSer: 4.056 ± 0.031	3.508GluThr: 3.508 ± 0.03	3.65GluVal: 3.65 ± 0.029	0.906GluTrp: 0.906 ± 0.014	1.566GluTyr: 1.566 ± 0.016	0.0GluXaa: 0.0 ± 0.0
Phe	3.334PheAla: 3.334 ± 0.029	0.573PheCys: 0.573 ± 0.01	2.388PheAsp: 2.388 ± 0.02	2.138PheGlu: 2.138 ± 0.019	1.653PhePhe: 1.653 ± 0.025	3.056PheGly: 3.056 ± 0.028	0.885PheHis: 0.885 ± 0.014	1.678PheIle: 1.678 ± 0.02	1.489PheLys: 1.489 ± 0.018	3.336PheLeu: 3.336 ± 0.031	0.792PheMet: 0.792 ± 0.014	1.442PheAsn: 1.442 ± 0.016	1.921PhePro: 1.921 ± 0.02	1.342PheGln: 1.342 ± 0.017	2.019PheArg: 2.019 ± 0.02	2.883PheSer: 2.883 ± 0.026	2.173PheThr: 2.173 ± 0.025	2.616PheVal: 2.616 ± 0.028	0.679PheTrp: 0.679 ± 0.012	1.132PheTyr: 1.132 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	6.067GlyAla: 6.067 ± 0.047	0.932GlyCys: 0.932 ± 0.015	3.865GlyAsp: 3.865 ± 0.03	3.679GlyGlu: 3.679 ± 0.026	2.996GlyPhe: 2.996 ± 0.025	6.784GlyGly: 6.784 ± 0.073	1.744GlyHis: 1.744 ± 0.02	3.424GlyIle: 3.424 ± 0.031	3.417GlyLys: 3.417 ± 0.028	6.265GlyLeu: 6.265 ± 0.042	1.611GlyMet: 1.611 ± 0.021	2.66GlyAsn: 2.66 ± 0.028	3.645GlyPro: 3.645 ± 0.034	2.557GlyGln: 2.557 ± 0.023	4.411GlyArg: 4.411 ± 0.033	5.781GlySer: 5.781 ± 0.054	4.255GlyThr: 4.255 ± 0.078	4.831GlyVal: 4.831 ± 0.034	1.247GlyTrp: 1.247 ± 0.016	2.172GlyTyr: 2.172 ± 0.023	0.0GlyXaa: 0.0 ± 0.0
His	1.903HisAla: 1.903 ± 0.019	0.34HisCys: 0.34 ± 0.008	1.338HisAsp: 1.338 ± 0.016	1.275HisGlu: 1.275 ± 0.016	0.93HisPhe: 0.93 ± 0.012	1.748HisGly: 1.748 ± 0.018	0.877HisHis: 0.877 ± 0.015	1.049HisIle: 1.049 ± 0.016	0.863HisLys: 0.863 ± 0.014	2.145HisLeu: 2.145 ± 0.021	0.518HisMet: 0.518 ± 0.009	0.797HisAsn: 0.797 ± 0.012	1.608HisPro: 1.608 ± 0.019	0.986HisGln: 0.986 ± 0.017	1.485HisArg: 1.485 ± 0.019	1.665HisSer: 1.665 ± 0.019	1.171HisThr: 1.171 ± 0.014	1.561HisVal: 1.561 ± 0.021	0.351HisTrp: 0.351 ± 0.009	0.666HisTyr: 0.666 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	4.069IleAla: 4.069 ± 0.028	0.644IleCys: 0.644 ± 0.011	2.628IleAsp: 2.628 ± 0.023	2.531IleGlu: 2.531 ± 0.024	1.847IlePhe: 1.847 ± 0.022	3.051IleGly: 3.051 ± 0.028	1.068IleHis: 1.068 ± 0.014	2.224IleIle: 2.224 ± 0.025	2.017IleLys: 2.017 ± 0.02	4.057IleLeu: 4.057 ± 0.032	0.972IleMet: 0.972 ± 0.014	1.653IleAsn: 1.653 ± 0.017	2.78IlePro: 2.78 ± 0.026	1.661IleGln: 1.661 ± 0.017	2.559IleArg: 2.559 ± 0.024	3.332IleSer: 3.332 ± 0.027	2.622IleThr: 2.622 ± 0.028	3.15IleVal: 3.15 ± 0.029	0.704IleTrp: 0.704 ± 0.012	1.247IleTyr: 1.247 ± 0.015	0.0IleXaa: 0.0 ± 0.0
Lys	4.378LysAla: 4.378 ± 0.039	0.49LysCys: 0.49 ± 0.012	2.721LysAsp: 2.721 ± 0.027	3.127LysGlu: 3.127 ± 0.03	1.425LysPhe: 1.425 ± 0.016	2.953LysGly: 2.953 ± 0.027	1.101LysHis: 1.101 ± 0.013	2.056LysIle: 2.056 ± 0.021	3.285LysLys: 3.285 ± 0.052	3.931LysLeu: 3.931 ± 0.029	1.018LysMet: 1.018 ± 0.015	1.661LysAsn: 1.661 ± 0.02	2.772LysPro: 2.772 ± 0.024	1.753LysGln: 1.753 ± 0.02	3.191LysArg: 3.191 ± 0.033	3.303LysSer: 3.303 ± 0.029	2.943LysThr: 2.943 ± 0.026	2.75LysVal: 2.75 ± 0.025	0.697LysTrp: 0.697 ± 0.011	1.301LysTyr: 1.301 ± 0.016	0.0LysXaa: 0.0 ± 0.0
Leu	8.348LeuAla: 8.348 ± 0.044	1.146LeuCys: 1.146 ± 0.017	5.104LeuAsp: 5.104 ± 0.034	5.173LeuGlu: 5.173 ± 0.035	3.28LeuPhe: 3.28 ± 0.031	6.155LeuGly: 6.155 ± 0.04	2.049LeuHis: 2.049 ± 0.026	3.507LeuIle: 3.507 ± 0.031	3.915LeuLys: 3.915 ± 0.036	7.964LeuLeu: 7.964 ± 0.057	1.766LeuMet: 1.766 ± 0.019	2.926LeuAsn: 2.926 ± 0.024	5.421LeuPro: 5.421 ± 0.043	3.451LeuGln: 3.451 ± 0.028	5.649LeuArg: 5.649 ± 0.035	6.725LeuSer: 6.725 ± 0.034	4.738LeuThr: 4.738 ± 0.037	5.767LeuVal: 5.767 ± 0.041	1.21LeuTrp: 1.21 ± 0.015	2.27LeuTyr: 2.27 ± 0.022	0.0LeuXaa: 0.0 ± 0.0
Met	2.448MetAla: 2.448 ± 0.022	0.253MetCys: 0.253 ± 0.007	1.258MetAsp: 1.258 ± 0.015	1.235MetGlu: 1.235 ± 0.015	0.774MetPhe: 0.774 ± 0.013	1.51MetGly: 1.51 ± 0.019	0.451MetHis: 0.451 ± 0.009	0.916MetIle: 0.916 ± 0.013	0.976MetLys: 0.976 ± 0.014	1.893MetLeu: 1.893 ± 0.021	0.607MetMet: 0.607 ± 0.012	0.756MetAsn: 0.756 ± 0.013	1.314MetPro: 1.314 ± 0.017	0.809MetGln: 0.809 ± 0.013	1.333MetArg: 1.333 ± 0.018	1.851MetSer: 1.851 ± 0.019	1.363MetThr: 1.363 ± 0.017	1.342MetVal: 1.342 ± 0.016	0.284MetTrp: 0.284 ± 0.006	0.539MetTyr: 0.539 ± 0.008	0.0MetXaa: 0.0 ± 0.0
Asn	3.127AsnAla: 3.127 ± 0.024	0.453AsnCys: 0.453 ± 0.01	1.897AsnAsp: 1.897 ± 0.02	1.843AsnGlu: 1.843 ± 0.018	1.395AsnPhe: 1.395 ± 0.017	3.043AsnGly: 3.043 ± 0.025	0.817AsnHis: 0.817 ± 0.013	1.847AsnIle: 1.847 ± 0.017	1.517AsnLys: 1.517 ± 0.017	3.103AsnLeu: 3.103 ± 0.03	0.856AsnMet: 0.856 ± 0.015	1.465AsnAsn: 1.465 ± 0.022	2.392AsnPro: 2.392 ± 0.023	1.218AsnGln: 1.218 ± 0.019	1.845AsnArg: 1.845 ± 0.016	2.494AsnSer: 2.494 ± 0.022	2.097AsnThr: 2.097 ± 0.019	2.393AsnVal: 2.393 ± 0.024	0.569AsnTrp: 0.569 ± 0.011	1.012AsnTyr: 1.012 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	6.051ProAla: 6.051 ± 0.053	0.494ProCys: 0.494 ± 0.009	3.316ProAsp: 3.316 ± 0.028	3.913ProGlu: 3.913 ± 0.039	2.054ProPhe: 2.054 ± 0.018	4.279ProGly: 4.279 ± 0.045	1.267ProHis: 1.267 ± 0.017	2.367ProIle: 2.367 ± 0.021	2.682ProLys: 2.682 ± 0.027	4.599ProLeu: 4.599 ± 0.034	1.1ProMet: 1.1 ± 0.013	2.112ProAsn: 2.112 ± 0.019	5.46ProPro: 5.46 ± 0.071	2.43ProGln: 2.43 ± 0.029	3.574ProArg: 3.574 ± 0.029	5.763ProSer: 5.763 ± 0.048	3.97ProThr: 3.97 ± 0.051	3.858ProVal: 3.858 ± 0.027	0.794ProTrp: 0.794 ± 0.012	1.454ProTyr: 1.454 ± 0.021	0.0ProXaa: 0.0 ± 0.0
Gln	3.524GlnAla: 3.524 ± 0.032	0.417GlnCys: 0.417 ± 0.01	1.97GlnAsp: 1.97 ± 0.02	2.147GlnGlu: 2.147 ± 0.021	1.205GlnPhe: 1.205 ± 0.016	2.341GlnGly: 2.341 ± 0.019	1.086GlnHis: 1.086 ± 0.018	1.67GlnIle: 1.67 ± 0.017	1.814GlnLys: 1.814 ± 0.019	3.289GlnLeu: 3.289 ± 0.03	0.907GlnMet: 0.907 ± 0.015	1.401GlnAsn: 1.401 ± 0.017	2.534GlnPro: 2.534 ± 0.031	2.714GlnGln: 2.714 ± 0.062	2.519GlnArg: 2.519 ± 0.024	2.763GlnSer: 2.763 ± 0.024	2.263GlnThr: 2.263 ± 0.028	2.194GlnVal: 2.194 ± 0.021	0.557GlnTrp: 0.557 ± 0.011	1.076GlnTyr: 1.076 ± 0.015	0.0GlnXaa: 0.0 ± 0.0
Arg	4.927ArgAla: 4.927 ± 0.03	0.738ArgCys: 0.738 ± 0.013	3.555ArgAsp: 3.555 ± 0.034	3.779ArgGlu: 3.779 ± 0.038	2.179ArgPhe: 2.179 ± 0.02	3.934ArgGly: 3.934 ± 0.032	1.623ArgHis: 1.623 ± 0.017	2.649ArgIle: 2.649 ± 0.022	3.263ArgLys: 3.263 ± 0.034	5.373ArgLeu: 5.373 ± 0.04	1.334ArgMet: 1.334 ± 0.015	2.214ArgAsn: 2.214 ± 0.02	3.625ArgPro: 3.625 ± 0.03	2.607ArgGln: 2.607 ± 0.024	5.296ArgArg: 5.296 ± 0.044	4.576ArgSer: 4.576 ± 0.041	3.244ArgThr: 3.244 ± 0.026	3.612ArgVal: 3.612 ± 0.027	0.976ArgTrp: 0.976 ± 0.014	1.622ArgTyr: 1.622 ± 0.017	0.0ArgXaa: 0.0 ± 0.0
Ser	7.025SerAla: 7.025 ± 0.043	0.857SerCys: 0.857 ± 0.012	4.103SerAsp: 4.103 ± 0.037	3.872SerGlu: 3.872 ± 0.033	2.98SerPhe: 2.98 ± 0.024	5.656SerGly: 5.656 ± 0.053	1.812SerHis: 1.812 ± 0.02	3.497SerIle: 3.497 ± 0.028	3.447SerLys: 3.447 ± 0.03	6.721SerLeu: 6.721 ± 0.043	1.66SerMet: 1.66 ± 0.017	2.705SerAsn: 2.705 ± 0.025	5.337SerPro: 5.337 ± 0.05	2.991SerGln: 2.991 ± 0.027	4.873SerArg: 4.873 ± 0.039	8.144SerSer: 8.144 ± 0.07	5.164SerThr: 5.164 ± 0.057	4.727SerVal: 4.727 ± 0.033	1.137SerTrp: 1.137 ± 0.015	1.986SerTyr: 1.986 ± 0.023	0.0SerXaa: 0.0 ± 0.0
Thr	5.694ThrAla: 5.694 ± 0.047	0.754ThrCys: 0.754 ± 0.012	2.888ThrAsp: 2.888 ± 0.022	3.006ThrGlu: 3.006 ± 0.026	2.255ThrPhe: 2.255 ± 0.022	4.346ThrGly: 4.346 ± 0.051	1.214ThrHis: 1.214 ± 0.015	2.888ThrIle: 2.888 ± 0.045	2.557ThrLys: 2.557 ± 0.025	5.057ThrLeu: 5.057 ± 0.041	1.174ThrMet: 1.174 ± 0.017	2.035ThrAsn: 2.035 ± 0.017	4.387ThrPro: 4.387 ± 0.04	2.029ThrGln: 2.029 ± 0.022	3.141ThrArg: 3.141 ± 0.022	5.11ThrSer: 5.11 ± 0.059	4.389ThrThr: 4.389 ± 0.081	4.026ThrVal: 4.026 ± 0.065	0.922ThrTrp: 0.922 ± 0.014	1.627ThrTyr: 1.627 ± 0.019	0.0ThrXaa: 0.0 ± 0.0
Val	6.16ValAla: 6.16 ± 0.043	0.877ValCys: 0.877 ± 0.013	4.065ValAsp: 4.065 ± 0.03	4.045ValGlu: 4.045 ± 0.031	2.71ValPhe: 2.71 ± 0.027	4.461ValGly: 4.461 ± 0.037	1.382ValHis: 1.382 ± 0.017	2.899ValIle: 2.899 ± 0.03	2.97ValLys: 2.97 ± 0.026	5.847ValLeu: 5.847 ± 0.039	1.421ValMet: 1.421 ± 0.016	2.297ValAsn: 2.297 ± 0.021	3.895ValPro: 3.895 ± 0.036	2.324ValGln: 2.324 ± 0.019	3.637ValArg: 3.637 ± 0.028	4.805ValSer: 4.805 ± 0.033	3.879ValThr: 3.879 ± 0.042	5.067ValVal: 5.067 ± 0.041	0.989ValTrp: 0.989 ± 0.013	1.811ValTyr: 1.811 ± 0.02	0.0ValXaa: 0.0 ± 0.0
Trp	1.263TrpAla: 1.263 ± 0.016	0.215TrpCys: 0.215 ± 0.006	0.96TrpAsp: 0.96 ± 0.015	0.85TrpGlu: 0.85 ± 0.013	0.584TrpPhe: 0.584 ± 0.011	1.007TrpGly: 1.007 ± 0.014	0.382TrpHis: 0.382 ± 0.008	0.736TrpIle: 0.736 ± 0.012	0.796TrpLys: 0.796 ± 0.013	1.403TrpLeu: 1.403 ± 0.018	0.388TrpMet: 0.388 ± 0.008	0.65TrpAsn: 0.65 ± 0.011	0.668TrpPro: 0.668 ± 0.013	0.592TrpGln: 0.592 ± 0.012	0.986TrpArg: 0.986 ± 0.014	1.085TrpSer: 1.085 ± 0.014	1.003TrpThr: 1.003 ± 0.013	0.931TrpVal: 0.931 ± 0.015	0.309TrpTrp: 0.309 ± 0.008	0.463TrpTyr: 0.463 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.224TyrAla: 2.224 ± 0.022	0.403TyrCys: 0.403 ± 0.009	1.705TyrAsp: 1.705 ± 0.02	1.491TyrGlu: 1.491 ± 0.016	1.174TyrPhe: 1.174 ± 0.016	2.112TyrGly: 2.112 ± 0.024	0.744TyrHis: 0.744 ± 0.012	1.245TyrIle: 1.245 ± 0.017	1.061TyrLys: 1.061 ± 0.014	2.524TyrLeu: 2.524 ± 0.02	0.613TyrMet: 0.613 ± 0.01	1.083TyrAsn: 1.083 ± 0.015	1.437TyrPro: 1.437 ± 0.017	1.009TyrGln: 1.009 ± 0.015	1.603TyrArg: 1.603 ± 0.02	1.898TyrSer: 1.898 ± 0.022	1.568TyrThr: 1.568 ± 0.024	1.71TyrVal: 1.71 ± 0.02	0.479TyrTrp: 0.479 ± 0.011	0.901TyrTyr: 0.901 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 12236 proteins (5682910 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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