Hepatitis E virus genotype 1 (isolate Human/China/HeBei/1987) (HEV)
Taxonomy: Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes; Hepelivirales; Hepeviridae; Orthohepevirus; Orthohepevirus A
Average proteome isoelectric point is 7.76
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Virtual 2D-PAGE plot for 4 proteins (isoelectric point calculated using IPC2_protein)
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Summary statistics related to proteome-wise predictions
Protein with the lowest isoelectric point:
>sp|Q81870|ORF3_HEVCH Protein ORF3 OS=Hepatitis E virus genotype 1 (isolate Human/China/HeBei/1987) OX=652674 GN=ORF3 PE=1 SV=2
MM1 pKa = 7.57EE2 pKa = 4.63AHH4 pKa = 6.14QFIKK8 pKa = 10.91APGITTAIEE17 pKa = 3.89QAALAAANSALANAVVVRR35 pKa = 11.84PFLSHH40 pKa = 4.88QQIEE44 pKa = 4.15ILINLMQPRR53 pKa = 11.84QLVFRR58 pKa = 11.84PEE60 pKa = 4.24VFWNHH65 pKa = 6.73PIQRR69 pKa = 11.84VIHH72 pKa = 6.4NEE74 pKa = 3.55LEE76 pKa = 4.32LYY78 pKa = 10.41CRR80 pKa = 11.84ARR82 pKa = 11.84SGRR85 pKa = 11.84CLEE88 pKa = 4.45IGAHH92 pKa = 5.74PRR94 pKa = 11.84SINDD98 pKa = 3.23NPNVVHH104 pKa = 7.25RR105 pKa = 11.84CFLRR109 pKa = 11.84PAGRR113 pKa = 11.84DD114 pKa = 3.29VQRR117 pKa = 11.84WYY119 pKa = 8.92TAPTRR124 pKa = 11.84GPAANCRR131 pKa = 11.84RR132 pKa = 11.84SALRR136 pKa = 11.84GLPAADD142 pKa = 3.02RR143 pKa = 11.84TYY145 pKa = 11.23CFDD148 pKa = 4.22GFSGCNFPAEE158 pKa = 4.34TGVALYY164 pKa = 10.02SLHH167 pKa = 7.32DD168 pKa = 3.86MSPSDD173 pKa = 3.32VAEE176 pKa = 3.74AMFRR180 pKa = 11.84HH181 pKa = 5.77GMTRR185 pKa = 11.84LYY187 pKa = 10.76AALHH191 pKa = 6.09LPPEE195 pKa = 4.34VLLPPGTYY203 pKa = 8.37RR204 pKa = 11.84TASYY208 pKa = 11.29LLIHH212 pKa = 7.25DD213 pKa = 4.03GRR215 pKa = 11.84RR216 pKa = 11.84VVVTYY221 pKa = 10.7EE222 pKa = 4.09GDD224 pKa = 3.0TSAGYY229 pKa = 9.57NHH231 pKa = 7.39DD232 pKa = 3.79VSNLRR237 pKa = 11.84SWIRR241 pKa = 11.84TTKK244 pKa = 9.32VTGDD248 pKa = 3.46HH249 pKa = 6.7PLVIEE254 pKa = 4.17RR255 pKa = 11.84VRR257 pKa = 11.84AIGCHH262 pKa = 5.35FVLLLTAAPEE272 pKa = 4.21PSPTPYY278 pKa = 10.22VPYY281 pKa = 10.04PRR283 pKa = 11.84STEE286 pKa = 3.98VYY288 pKa = 8.33VRR290 pKa = 11.84SIFGPGGTPSLFPTSCSTKK309 pKa = 8.79STFHH313 pKa = 6.86AVPAHH318 pKa = 5.0IWDD321 pKa = 3.72RR322 pKa = 11.84LMLFGATLDD331 pKa = 4.16DD332 pKa = 4.5QAFCCSRR339 pKa = 11.84LMTYY343 pKa = 10.53LRR345 pKa = 11.84GISYY349 pKa = 10.34KK350 pKa = 9.24VTVGTLVANEE360 pKa = 4.02GWNASEE366 pKa = 4.24VALTAVITAAYY377 pKa = 8.25LTICHH382 pKa = 5.39QRR384 pKa = 11.84YY385 pKa = 9.04LRR387 pKa = 11.84TQAISKK393 pKa = 9.62GMRR396 pKa = 11.84RR397 pKa = 11.84LEE399 pKa = 3.98RR400 pKa = 11.84EE401 pKa = 3.86HH402 pKa = 6.01AQKK405 pKa = 10.82FITRR409 pKa = 11.84LYY411 pKa = 9.12SWLFEE416 pKa = 4.19KK417 pKa = 10.38SGRR420 pKa = 11.84DD421 pKa = 3.81YY422 pKa = 11.22IPGRR426 pKa = 11.84QLEE429 pKa = 4.96FYY431 pKa = 9.31AQCRR435 pKa = 11.84RR436 pKa = 11.84WLSAGFHH443 pKa = 6.74LDD445 pKa = 3.18PRR447 pKa = 11.84VLVFDD452 pKa = 4.62EE453 pKa = 5.0SAPCHH458 pKa = 6.34CRR460 pKa = 11.84TAIRR464 pKa = 11.84KK465 pKa = 8.45AVSKK469 pKa = 8.75FCCFMKK475 pKa = 10.28WLGQEE480 pKa = 4.51CTCFLQPAEE489 pKa = 4.45GAVGDD494 pKa = 3.92QGHH497 pKa = 7.22DD498 pKa = 3.24NEE500 pKa = 5.13AYY502 pKa = 9.75EE503 pKa = 5.0GSDD506 pKa = 3.26VDD508 pKa = 3.98PAEE511 pKa = 4.27SAISDD516 pKa = 3.23ISGSYY521 pKa = 8.87VVPGTALQPLYY532 pKa = 10.5QALDD536 pKa = 3.68LPAEE540 pKa = 4.14IVARR544 pKa = 11.84AGRR547 pKa = 11.84LTATVKK553 pKa = 10.33VSQVDD558 pKa = 3.62GRR560 pKa = 11.84IDD562 pKa = 4.13CEE564 pKa = 4.03TLLGNKK570 pKa = 7.47TFRR573 pKa = 11.84TSFVDD578 pKa = 4.03GAVLEE583 pKa = 4.68TNGPEE588 pKa = 3.75RR589 pKa = 11.84HH590 pKa = 6.04NLSFDD595 pKa = 3.43ASQSTMAAGPFSLTYY610 pKa = 9.96AASAAGLEE618 pKa = 4.15VRR620 pKa = 11.84YY621 pKa = 9.82VAAGLDD627 pKa = 3.58HH628 pKa = 7.04RR629 pKa = 11.84AVFAPGVSPRR639 pKa = 11.84SAPGEE644 pKa = 4.02VTAFCSALYY653 pKa = 10.21RR654 pKa = 11.84FNRR657 pKa = 11.84EE658 pKa = 3.7AQRR661 pKa = 11.84LSLTGNFWFHH671 pKa = 7.12PEE673 pKa = 3.77GLLGPFAPFSPGHH686 pKa = 4.97VWEE689 pKa = 4.76SANPFCGEE697 pKa = 3.8STLYY701 pKa = 9.5TRR703 pKa = 11.84TWSEE707 pKa = 3.43VDD709 pKa = 3.47AVSSPAQPDD718 pKa = 3.32LGFISEE724 pKa = 4.13PSIPSRR730 pKa = 11.84AATLTPAAPLPPPAPDD746 pKa = 4.08PSPTPSAPARR756 pKa = 11.84GEE758 pKa = 3.93PAPGATARR766 pKa = 11.84APAITHH772 pKa = 4.41QAARR776 pKa = 11.84HH777 pKa = 5.03RR778 pKa = 11.84RR779 pKa = 11.84LLFTYY784 pKa = 9.96PDD786 pKa = 3.74GSKK789 pKa = 10.66VFAGSLFEE797 pKa = 4.89STCTWLVNASNVDD810 pKa = 3.37HH811 pKa = 7.14RR812 pKa = 11.84PGGGLCHH819 pKa = 7.09AFYY822 pKa = 10.77QRR824 pKa = 11.84YY825 pKa = 7.18PASFDD830 pKa = 3.19AASFVMRR837 pKa = 11.84DD838 pKa = 2.94GAAAYY843 pKa = 7.51TLTPRR848 pKa = 11.84PIIHH852 pKa = 6.92AVAPDD857 pKa = 3.25YY858 pKa = 10.93RR859 pKa = 11.84LEE861 pKa = 4.62HH862 pKa = 5.83NPKK865 pKa = 9.04MLEE868 pKa = 3.4AAYY871 pKa = 10.5RR872 pKa = 11.84EE873 pKa = 4.4TCSRR877 pKa = 11.84LGTAAYY883 pKa = 8.09PLLGTGIYY891 pKa = 9.13QVPIGPSFDD900 pKa = 2.74AWEE903 pKa = 4.29RR904 pKa = 11.84NHH906 pKa = 7.21RR907 pKa = 11.84PGDD910 pKa = 3.68EE911 pKa = 4.4LYY913 pKa = 10.98LPEE916 pKa = 4.92LAARR920 pKa = 11.84WFEE923 pKa = 4.47ANRR926 pKa = 11.84PTCPTLTITEE936 pKa = 4.34DD937 pKa = 3.34VARR940 pKa = 11.84TANLAIEE947 pKa = 4.89LDD949 pKa = 3.67SATDD953 pKa = 3.23VGRR956 pKa = 11.84ACAGCRR962 pKa = 11.84VTPGVVQYY970 pKa = 10.88QFTAGVPGSGKK981 pKa = 10.06SRR983 pKa = 11.84SITQADD989 pKa = 3.35VDD991 pKa = 4.37VVVVPTRR998 pKa = 11.84EE999 pKa = 3.81LRR1001 pKa = 11.84NAWRR1005 pKa = 11.84RR1006 pKa = 11.84RR1007 pKa = 11.84GFAAFTPHH1015 pKa = 5.07TAARR1019 pKa = 11.84VTQGRR1024 pKa = 11.84RR1025 pKa = 11.84VVIDD1029 pKa = 3.97EE1030 pKa = 4.65APSLPPHH1037 pKa = 6.87LLLLHH1042 pKa = 5.78MQRR1045 pKa = 11.84AATVHH1050 pKa = 6.56LLGDD1054 pKa = 4.18PNQIPAIDD1062 pKa = 4.12FEE1064 pKa = 4.73HH1065 pKa = 6.99AGLVPAIRR1073 pKa = 11.84PDD1075 pKa = 3.84LAPTSWWHH1083 pKa = 4.24VTHH1086 pKa = 7.31RR1087 pKa = 11.84CPADD1091 pKa = 3.22VCEE1094 pKa = 5.5LIRR1097 pKa = 11.84GAYY1100 pKa = 9.61PMIQTTSRR1108 pKa = 11.84VLRR1111 pKa = 11.84SLFWGEE1117 pKa = 3.62PAVGQKK1123 pKa = 10.54LVFTQAAKK1131 pKa = 10.21AANPGSVTVHH1141 pKa = 6.28EE1142 pKa = 4.71AQGATYY1148 pKa = 10.23TEE1150 pKa = 4.16TTIIATADD1158 pKa = 3.21ARR1160 pKa = 11.84GLIQSSRR1167 pKa = 11.84AHH1169 pKa = 6.84AIVALTRR1176 pKa = 11.84HH1177 pKa = 5.34TEE1179 pKa = 3.6KK1180 pKa = 10.78CVIIDD1185 pKa = 3.46APGLLRR1191 pKa = 11.84EE1192 pKa = 4.41VGISDD1197 pKa = 5.48AIVNNFFLAGGEE1209 pKa = 4.15IGHH1212 pKa = 5.98QRR1214 pKa = 11.84PSVIPRR1220 pKa = 11.84GNPDD1224 pKa = 3.52ANVDD1228 pKa = 3.72TLAAFPPSCQISAFHH1243 pKa = 6.15QLAEE1247 pKa = 4.37EE1248 pKa = 4.52LGHH1251 pKa = 6.77RR1252 pKa = 11.84PAPVAAVLPPCPEE1265 pKa = 4.2LEE1267 pKa = 4.08QGLLYY1272 pKa = 10.62LPQEE1276 pKa = 4.29LTTCDD1281 pKa = 3.24SVVTFEE1287 pKa = 4.48LTDD1290 pKa = 3.41IVHH1293 pKa = 6.8CRR1295 pKa = 11.84MAAPSQRR1302 pKa = 11.84KK1303 pKa = 8.38AVLSTLVGHH1312 pKa = 6.18YY1313 pKa = 10.13GRR1315 pKa = 11.84RR1316 pKa = 11.84TKK1318 pKa = 10.6LYY1320 pKa = 8.81NASHH1324 pKa = 6.61SDD1326 pKa = 3.4VRR1328 pKa = 11.84DD1329 pKa = 3.31SLARR1333 pKa = 11.84FIPAIGHH1340 pKa = 4.85VQVTTCEE1347 pKa = 3.94LYY1349 pKa = 10.59EE1350 pKa = 4.06LVEE1353 pKa = 4.12AMVEE1357 pKa = 4.04KK1358 pKa = 10.67GQDD1361 pKa = 3.16GSAVLEE1367 pKa = 4.15LDD1369 pKa = 3.29LCNRR1373 pKa = 11.84DD1374 pKa = 3.02VSRR1377 pKa = 11.84ITFFQKK1383 pKa = 10.55DD1384 pKa = 3.93CNKK1387 pKa = 8.61FTTGEE1392 pKa = 4.24TIAHH1396 pKa = 5.9GKK1398 pKa = 8.77VGQGISAWSKK1408 pKa = 6.94TFCALFGPWFRR1419 pKa = 11.84AIEE1422 pKa = 4.02KK1423 pKa = 10.41AILALLPQGVFYY1435 pKa = 11.34GDD1437 pKa = 4.07AFDD1440 pKa = 4.55DD1441 pKa = 4.43TVFSAAVAAARR1452 pKa = 11.84ASMVFEE1458 pKa = 4.4NDD1460 pKa = 2.7FSEE1463 pKa = 5.59FDD1465 pKa = 3.36STQNNFSLGLEE1476 pKa = 4.07CAIMVEE1482 pKa = 4.49CGMPQWLIRR1491 pKa = 11.84LYY1493 pKa = 10.88HH1494 pKa = 7.17LIRR1497 pKa = 11.84SAWILQAPKK1506 pKa = 10.26EE1507 pKa = 4.23SLRR1510 pKa = 11.84GFWKK1514 pKa = 10.1KK1515 pKa = 10.16HH1516 pKa = 4.77SGEE1519 pKa = 4.38PGTLLWNTVWNMAVITHH1536 pKa = 6.96CYY1538 pKa = 10.1DD1539 pKa = 3.28FRR1541 pKa = 11.84DD1542 pKa = 3.76LQVAAFKK1549 pKa = 11.05GDD1551 pKa = 3.77DD1552 pKa = 4.07SIVLCSEE1559 pKa = 4.01YY1560 pKa = 10.33RR1561 pKa = 11.84QSPGAAVLIAGCGLKK1576 pKa = 10.61LKK1578 pKa = 10.73VDD1580 pKa = 4.42FRR1582 pKa = 11.84PIGLYY1587 pKa = 10.44AGVVVAPGLGALPDD1601 pKa = 3.62VVRR1604 pKa = 11.84FAGRR1608 pKa = 11.84LTEE1611 pKa = 4.5KK1612 pKa = 10.41NWGPGPEE1619 pKa = 3.87RR1620 pKa = 11.84AKK1622 pKa = 10.26QLRR1625 pKa = 11.84LAVSDD1630 pKa = 4.18FLRR1633 pKa = 11.84KK1634 pKa = 8.27LTNVAQMCVDD1644 pKa = 3.66VVSRR1648 pKa = 11.84VYY1650 pKa = 10.56GVSPGLVHH1658 pKa = 6.67NLIGMLQAVADD1669 pKa = 4.89GKK1671 pKa = 10.94AHH1673 pKa = 5.47FTEE1676 pKa = 4.66SVKK1679 pKa = 10.67PVLDD1683 pKa = 3.58LTNSILCRR1691 pKa = 11.84VEE1693 pKa = 3.75
MM1 pKa = 7.57EE2 pKa = 4.63AHH4 pKa = 6.14QFIKK8 pKa = 10.91APGITTAIEE17 pKa = 3.89QAALAAANSALANAVVVRR35 pKa = 11.84PFLSHH40 pKa = 4.88QQIEE44 pKa = 4.15ILINLMQPRR53 pKa = 11.84QLVFRR58 pKa = 11.84PEE60 pKa = 4.24VFWNHH65 pKa = 6.73PIQRR69 pKa = 11.84VIHH72 pKa = 6.4NEE74 pKa = 3.55LEE76 pKa = 4.32LYY78 pKa = 10.41CRR80 pKa = 11.84ARR82 pKa = 11.84SGRR85 pKa = 11.84CLEE88 pKa = 4.45IGAHH92 pKa = 5.74PRR94 pKa = 11.84SINDD98 pKa = 3.23NPNVVHH104 pKa = 7.25RR105 pKa = 11.84CFLRR109 pKa = 11.84PAGRR113 pKa = 11.84DD114 pKa = 3.29VQRR117 pKa = 11.84WYY119 pKa = 8.92TAPTRR124 pKa = 11.84GPAANCRR131 pKa = 11.84RR132 pKa = 11.84SALRR136 pKa = 11.84GLPAADD142 pKa = 3.02RR143 pKa = 11.84TYY145 pKa = 11.23CFDD148 pKa = 4.22GFSGCNFPAEE158 pKa = 4.34TGVALYY164 pKa = 10.02SLHH167 pKa = 7.32DD168 pKa = 3.86MSPSDD173 pKa = 3.32VAEE176 pKa = 3.74AMFRR180 pKa = 11.84HH181 pKa = 5.77GMTRR185 pKa = 11.84LYY187 pKa = 10.76AALHH191 pKa = 6.09LPPEE195 pKa = 4.34VLLPPGTYY203 pKa = 8.37RR204 pKa = 11.84TASYY208 pKa = 11.29LLIHH212 pKa = 7.25DD213 pKa = 4.03GRR215 pKa = 11.84RR216 pKa = 11.84VVVTYY221 pKa = 10.7EE222 pKa = 4.09GDD224 pKa = 3.0TSAGYY229 pKa = 9.57NHH231 pKa = 7.39DD232 pKa = 3.79VSNLRR237 pKa = 11.84SWIRR241 pKa = 11.84TTKK244 pKa = 9.32VTGDD248 pKa = 3.46HH249 pKa = 6.7PLVIEE254 pKa = 4.17RR255 pKa = 11.84VRR257 pKa = 11.84AIGCHH262 pKa = 5.35FVLLLTAAPEE272 pKa = 4.21PSPTPYY278 pKa = 10.22VPYY281 pKa = 10.04PRR283 pKa = 11.84STEE286 pKa = 3.98VYY288 pKa = 8.33VRR290 pKa = 11.84SIFGPGGTPSLFPTSCSTKK309 pKa = 8.79STFHH313 pKa = 6.86AVPAHH318 pKa = 5.0IWDD321 pKa = 3.72RR322 pKa = 11.84LMLFGATLDD331 pKa = 4.16DD332 pKa = 4.5QAFCCSRR339 pKa = 11.84LMTYY343 pKa = 10.53LRR345 pKa = 11.84GISYY349 pKa = 10.34KK350 pKa = 9.24VTVGTLVANEE360 pKa = 4.02GWNASEE366 pKa = 4.24VALTAVITAAYY377 pKa = 8.25LTICHH382 pKa = 5.39QRR384 pKa = 11.84YY385 pKa = 9.04LRR387 pKa = 11.84TQAISKK393 pKa = 9.62GMRR396 pKa = 11.84RR397 pKa = 11.84LEE399 pKa = 3.98RR400 pKa = 11.84EE401 pKa = 3.86HH402 pKa = 6.01AQKK405 pKa = 10.82FITRR409 pKa = 11.84LYY411 pKa = 9.12SWLFEE416 pKa = 4.19KK417 pKa = 10.38SGRR420 pKa = 11.84DD421 pKa = 3.81YY422 pKa = 11.22IPGRR426 pKa = 11.84QLEE429 pKa = 4.96FYY431 pKa = 9.31AQCRR435 pKa = 11.84RR436 pKa = 11.84WLSAGFHH443 pKa = 6.74LDD445 pKa = 3.18PRR447 pKa = 11.84VLVFDD452 pKa = 4.62EE453 pKa = 5.0SAPCHH458 pKa = 6.34CRR460 pKa = 11.84TAIRR464 pKa = 11.84KK465 pKa = 8.45AVSKK469 pKa = 8.75FCCFMKK475 pKa = 10.28WLGQEE480 pKa = 4.51CTCFLQPAEE489 pKa = 4.45GAVGDD494 pKa = 3.92QGHH497 pKa = 7.22DD498 pKa = 3.24NEE500 pKa = 5.13AYY502 pKa = 9.75EE503 pKa = 5.0GSDD506 pKa = 3.26VDD508 pKa = 3.98PAEE511 pKa = 4.27SAISDD516 pKa = 3.23ISGSYY521 pKa = 8.87VVPGTALQPLYY532 pKa = 10.5QALDD536 pKa = 3.68LPAEE540 pKa = 4.14IVARR544 pKa = 11.84AGRR547 pKa = 11.84LTATVKK553 pKa = 10.33VSQVDD558 pKa = 3.62GRR560 pKa = 11.84IDD562 pKa = 4.13CEE564 pKa = 4.03TLLGNKK570 pKa = 7.47TFRR573 pKa = 11.84TSFVDD578 pKa = 4.03GAVLEE583 pKa = 4.68TNGPEE588 pKa = 3.75RR589 pKa = 11.84HH590 pKa = 6.04NLSFDD595 pKa = 3.43ASQSTMAAGPFSLTYY610 pKa = 9.96AASAAGLEE618 pKa = 4.15VRR620 pKa = 11.84YY621 pKa = 9.82VAAGLDD627 pKa = 3.58HH628 pKa = 7.04RR629 pKa = 11.84AVFAPGVSPRR639 pKa = 11.84SAPGEE644 pKa = 4.02VTAFCSALYY653 pKa = 10.21RR654 pKa = 11.84FNRR657 pKa = 11.84EE658 pKa = 3.7AQRR661 pKa = 11.84LSLTGNFWFHH671 pKa = 7.12PEE673 pKa = 3.77GLLGPFAPFSPGHH686 pKa = 4.97VWEE689 pKa = 4.76SANPFCGEE697 pKa = 3.8STLYY701 pKa = 9.5TRR703 pKa = 11.84TWSEE707 pKa = 3.43VDD709 pKa = 3.47AVSSPAQPDD718 pKa = 3.32LGFISEE724 pKa = 4.13PSIPSRR730 pKa = 11.84AATLTPAAPLPPPAPDD746 pKa = 4.08PSPTPSAPARR756 pKa = 11.84GEE758 pKa = 3.93PAPGATARR766 pKa = 11.84APAITHH772 pKa = 4.41QAARR776 pKa = 11.84HH777 pKa = 5.03RR778 pKa = 11.84RR779 pKa = 11.84LLFTYY784 pKa = 9.96PDD786 pKa = 3.74GSKK789 pKa = 10.66VFAGSLFEE797 pKa = 4.89STCTWLVNASNVDD810 pKa = 3.37HH811 pKa = 7.14RR812 pKa = 11.84PGGGLCHH819 pKa = 7.09AFYY822 pKa = 10.77QRR824 pKa = 11.84YY825 pKa = 7.18PASFDD830 pKa = 3.19AASFVMRR837 pKa = 11.84DD838 pKa = 2.94GAAAYY843 pKa = 7.51TLTPRR848 pKa = 11.84PIIHH852 pKa = 6.92AVAPDD857 pKa = 3.25YY858 pKa = 10.93RR859 pKa = 11.84LEE861 pKa = 4.62HH862 pKa = 5.83NPKK865 pKa = 9.04MLEE868 pKa = 3.4AAYY871 pKa = 10.5RR872 pKa = 11.84EE873 pKa = 4.4TCSRR877 pKa = 11.84LGTAAYY883 pKa = 8.09PLLGTGIYY891 pKa = 9.13QVPIGPSFDD900 pKa = 2.74AWEE903 pKa = 4.29RR904 pKa = 11.84NHH906 pKa = 7.21RR907 pKa = 11.84PGDD910 pKa = 3.68EE911 pKa = 4.4LYY913 pKa = 10.98LPEE916 pKa = 4.92LAARR920 pKa = 11.84WFEE923 pKa = 4.47ANRR926 pKa = 11.84PTCPTLTITEE936 pKa = 4.34DD937 pKa = 3.34VARR940 pKa = 11.84TANLAIEE947 pKa = 4.89LDD949 pKa = 3.67SATDD953 pKa = 3.23VGRR956 pKa = 11.84ACAGCRR962 pKa = 11.84VTPGVVQYY970 pKa = 10.88QFTAGVPGSGKK981 pKa = 10.06SRR983 pKa = 11.84SITQADD989 pKa = 3.35VDD991 pKa = 4.37VVVVPTRR998 pKa = 11.84EE999 pKa = 3.81LRR1001 pKa = 11.84NAWRR1005 pKa = 11.84RR1006 pKa = 11.84RR1007 pKa = 11.84GFAAFTPHH1015 pKa = 5.07TAARR1019 pKa = 11.84VTQGRR1024 pKa = 11.84RR1025 pKa = 11.84VVIDD1029 pKa = 3.97EE1030 pKa = 4.65APSLPPHH1037 pKa = 6.87LLLLHH1042 pKa = 5.78MQRR1045 pKa = 11.84AATVHH1050 pKa = 6.56LLGDD1054 pKa = 4.18PNQIPAIDD1062 pKa = 4.12FEE1064 pKa = 4.73HH1065 pKa = 6.99AGLVPAIRR1073 pKa = 11.84PDD1075 pKa = 3.84LAPTSWWHH1083 pKa = 4.24VTHH1086 pKa = 7.31RR1087 pKa = 11.84CPADD1091 pKa = 3.22VCEE1094 pKa = 5.5LIRR1097 pKa = 11.84GAYY1100 pKa = 9.61PMIQTTSRR1108 pKa = 11.84VLRR1111 pKa = 11.84SLFWGEE1117 pKa = 3.62PAVGQKK1123 pKa = 10.54LVFTQAAKK1131 pKa = 10.21AANPGSVTVHH1141 pKa = 6.28EE1142 pKa = 4.71AQGATYY1148 pKa = 10.23TEE1150 pKa = 4.16TTIIATADD1158 pKa = 3.21ARR1160 pKa = 11.84GLIQSSRR1167 pKa = 11.84AHH1169 pKa = 6.84AIVALTRR1176 pKa = 11.84HH1177 pKa = 5.34TEE1179 pKa = 3.6KK1180 pKa = 10.78CVIIDD1185 pKa = 3.46APGLLRR1191 pKa = 11.84EE1192 pKa = 4.41VGISDD1197 pKa = 5.48AIVNNFFLAGGEE1209 pKa = 4.15IGHH1212 pKa = 5.98QRR1214 pKa = 11.84PSVIPRR1220 pKa = 11.84GNPDD1224 pKa = 3.52ANVDD1228 pKa = 3.72TLAAFPPSCQISAFHH1243 pKa = 6.15QLAEE1247 pKa = 4.37EE1248 pKa = 4.52LGHH1251 pKa = 6.77RR1252 pKa = 11.84PAPVAAVLPPCPEE1265 pKa = 4.2LEE1267 pKa = 4.08QGLLYY1272 pKa = 10.62LPQEE1276 pKa = 4.29LTTCDD1281 pKa = 3.24SVVTFEE1287 pKa = 4.48LTDD1290 pKa = 3.41IVHH1293 pKa = 6.8CRR1295 pKa = 11.84MAAPSQRR1302 pKa = 11.84KK1303 pKa = 8.38AVLSTLVGHH1312 pKa = 6.18YY1313 pKa = 10.13GRR1315 pKa = 11.84RR1316 pKa = 11.84TKK1318 pKa = 10.6LYY1320 pKa = 8.81NASHH1324 pKa = 6.61SDD1326 pKa = 3.4VRR1328 pKa = 11.84DD1329 pKa = 3.31SLARR1333 pKa = 11.84FIPAIGHH1340 pKa = 4.85VQVTTCEE1347 pKa = 3.94LYY1349 pKa = 10.59EE1350 pKa = 4.06LVEE1353 pKa = 4.12AMVEE1357 pKa = 4.04KK1358 pKa = 10.67GQDD1361 pKa = 3.16GSAVLEE1367 pKa = 4.15LDD1369 pKa = 3.29LCNRR1373 pKa = 11.84DD1374 pKa = 3.02VSRR1377 pKa = 11.84ITFFQKK1383 pKa = 10.55DD1384 pKa = 3.93CNKK1387 pKa = 8.61FTTGEE1392 pKa = 4.24TIAHH1396 pKa = 5.9GKK1398 pKa = 8.77VGQGISAWSKK1408 pKa = 6.94TFCALFGPWFRR1419 pKa = 11.84AIEE1422 pKa = 4.02KK1423 pKa = 10.41AILALLPQGVFYY1435 pKa = 11.34GDD1437 pKa = 4.07AFDD1440 pKa = 4.55DD1441 pKa = 4.43TVFSAAVAAARR1452 pKa = 11.84ASMVFEE1458 pKa = 4.4NDD1460 pKa = 2.7FSEE1463 pKa = 5.59FDD1465 pKa = 3.36STQNNFSLGLEE1476 pKa = 4.07CAIMVEE1482 pKa = 4.49CGMPQWLIRR1491 pKa = 11.84LYY1493 pKa = 10.88HH1494 pKa = 7.17LIRR1497 pKa = 11.84SAWILQAPKK1506 pKa = 10.26EE1507 pKa = 4.23SLRR1510 pKa = 11.84GFWKK1514 pKa = 10.1KK1515 pKa = 10.16HH1516 pKa = 4.77SGEE1519 pKa = 4.38PGTLLWNTVWNMAVITHH1536 pKa = 6.96CYY1538 pKa = 10.1DD1539 pKa = 3.28FRR1541 pKa = 11.84DD1542 pKa = 3.76LQVAAFKK1549 pKa = 11.05GDD1551 pKa = 3.77DD1552 pKa = 4.07SIVLCSEE1559 pKa = 4.01YY1560 pKa = 10.33RR1561 pKa = 11.84QSPGAAVLIAGCGLKK1576 pKa = 10.61LKK1578 pKa = 10.73VDD1580 pKa = 4.42FRR1582 pKa = 11.84PIGLYY1587 pKa = 10.44AGVVVAPGLGALPDD1601 pKa = 3.62VVRR1604 pKa = 11.84FAGRR1608 pKa = 11.84LTEE1611 pKa = 4.5KK1612 pKa = 10.41NWGPGPEE1619 pKa = 3.87RR1620 pKa = 11.84AKK1622 pKa = 10.26QLRR1625 pKa = 11.84LAVSDD1630 pKa = 4.18FLRR1633 pKa = 11.84KK1634 pKa = 8.27LTNVAQMCVDD1644 pKa = 3.66VVSRR1648 pKa = 11.84VYY1650 pKa = 10.56GVSPGLVHH1658 pKa = 6.67NLIGMLQAVADD1669 pKa = 4.89GKK1671 pKa = 10.94AHH1673 pKa = 5.47FTEE1676 pKa = 4.66SVKK1679 pKa = 10.67PVLDD1683 pKa = 3.58LTNSILCRR1691 pKa = 11.84VEE1693 pKa = 3.75
Molecular weight: 185.05 kDa
Isoelectric point according different methods:
Protein with the highest isoelectric point:
>sp|Q81871|CAPSD_HEVCH Secreted protein ORF2 OS=Hepatitis E virus genotype 1 (isolate Human/China/HeBei/1987) OX=652674 GN=ORF2 PE=1 SV=1
MM1 pKa = 7.75GSRR4 pKa = 11.84PCALGLFCCCSSCFCLCCPRR24 pKa = 11.84HH25 pKa = 5.95RR26 pKa = 11.84PVSRR30 pKa = 11.84LAAAVGGAAAVPAVVSGVTGLILSPSQSPIFIQPTPSPPMSPLRR74 pKa = 11.84PGLDD78 pKa = 2.99LVFANPPDD86 pKa = 3.5HH87 pKa = 6.75SAPLGVTRR95 pKa = 11.84PSAPPLPHH103 pKa = 7.32VVDD106 pKa = 5.35LPQLGPRR113 pKa = 11.84RR114 pKa = 3.8
MM1 pKa = 7.75GSRR4 pKa = 11.84PCALGLFCCCSSCFCLCCPRR24 pKa = 11.84HH25 pKa = 5.95RR26 pKa = 11.84PVSRR30 pKa = 11.84LAAAVGGAAAVPAVVSGVTGLILSPSQSPIFIQPTPSPPMSPLRR74 pKa = 11.84PGLDD78 pKa = 2.99LVFANPPDD86 pKa = 3.5HH87 pKa = 6.75SAPLGVTRR95 pKa = 11.84PSAPPLPHH103 pKa = 7.32VVDD106 pKa = 5.35LPQLGPRR113 pKa = 11.84RR114 pKa = 3.8
Molecular weight: 11.68 kDa
Isoelectric point according different methods:
Peptides (in silico digests for buttom-up proteomics)
Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.| Try ESI |
 |
|---|
| ChTry ESI |
|
|---|
| ArgC ESI |
|
|---|
| LysN ESI |
|
|---|
| TryLysC ESI |
|
|---|
| Try MALDI |
|
|---|
| ChTry MALDI |
|
|---|
| ArgC MALDI |
|
|---|
| LysN MALDI |
|
|---|
| TryLysC MALDI |
|
|---|
| Try LTQ |
|
|---|
| ChTry LTQ |
|
|---|
| ArgC LTQ |
|
|---|
| LysN LTQ |
|
|---|
| TryLysC LTQ |
|
|---|
| Try MSlow |
|
|---|
| ChTry MSlow |
|
|---|
| ArgC MSlow |
|
|---|
| LysN MSlow |
|
|---|
| TryLysC MSlow |
|
|---|
| Try MShigh |
|
|---|
| ChTry MShigh |
|
|---|
| ArgC MShigh |
|
|---|
| LysN MShigh |
|
|---|
| TryLysC MShigh |
|
|---|
General Statistics
Number of major isoforms |
Number of additional isoforms |
Number of all proteins |
Number of amino acids |
Min. Seq. Length |
Max. Seq. Length |
Avg. Seq. Length |
Avg. Mol. Weight |
|---|---|---|---|---|---|---|---|
3112 |
114 |
1693 |
778.0 |
84.22 |
Amino acid frequency
Ala |
Cys |
Asp |
Glu |
Phe |
Gly |
His |
Ile |
Lys |
Leu |
|---|---|---|---|---|---|---|---|---|---|
11.215 ± 0.339 | 1.96 ± 0.629 |
4.434 ± 0.116 | 4.145 ± 0.554 |
3.695 ± 0.553 | 7.455 ± 0.295 |
2.603 ± 0.411 | 3.792 ± 0.319 |
1.832 ± 0.257 | 9.383 ± 0.284 |
Met |
Asn |
Gln |
Pro |
Arg |
Ser |
Thr |
Val |
Trp |
Tyr |
|---|---|---|---|---|---|---|---|---|---|
1.285 ± 0.057 | 2.988 ± 0.25 |
7.841 ± 0.79 | 3.503 ± 0.155 |
7.23 ± 0.068 | 7.294 ± 0.759 |
7.712 ± 0.996 | 7.262 ± 0.248 |
1.285 ± 0.181 | 3.085 ± 0.284 |
Most of the basic statistics you can see at this page can be downloaded from this CSV file
See this proteome in:
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here
| Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 | Contact: Lukasz P. Kozlowski |